HFE gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_139010.3	NP_620579.1	hereditary hemochromatosis protein isoform 10 precursor
NM_139004.3	NP_620573.1	hereditary hemochromatosis protein isoform 4 precursor
NM_139004.2	NP_620573.1	hereditary hemochromatosis protein isoform 4 precursor
NM_139010.2	NP_620579.1	hereditary hemochromatosis protein isoform 10 precursor
NM_139007.2	NP_620576.1	hereditary hemochromatosis protein isoform 7 precursor
NM_139011.3	NP_620580.1	hereditary hemochromatosis protein isoform 11 precursor
NM_139009.2	NP_620578.1	hereditary hemochromatosis protein isoform 9 precursor
NM_139006.3	NP_620575.1	hereditary hemochromatosis protein isoform 6 precursor
XM_011514543.3	XP_011512845.1	hereditary hemochromatosis protein isoform X1
NM_139008.2	NP_620577.1	hereditary hemochromatosis protein isoform 8 precursor
NM_139003.2	NP_620572.1	hereditary hemochromatosis protein isoform 3 precursor
NM_139011.2	NP_620580.1	hereditary hemochromatosis protein isoform 11 precursor
NM_139006.2	NP_620575.1	hereditary hemochromatosis protein isoform 6 precursor
NM_139008.3	NP_620577.1	hereditary hemochromatosis protein isoform 8 precursor
NM_139003.3	NP_620572.1	hereditary hemochromatosis protein isoform 3 precursor
NM_139009.3	NP_620578.1	hereditary hemochromatosis protein isoform 9 precursor
NM_000410.3	NP_000401.1	hereditary hemochromatosis protein isoform 1 precursor
NM_001300749.1	NP_001287678.1	hereditary hemochromatosis protein isoform 12 precursor
XM_011514543.2	XP_011512845.1	hereditary hemochromatosis protein isoform X1
NM_139007.3	NP_620576.1	hereditary hemochromatosis protein isoform 7 precursor
NM_001300749.2	NP_001287678.1	hereditary hemochromatosis protein isoform 12 precursor

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24991	NM_000410.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu24713	NM_139011.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu24786	NM_139006.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$195.30 $279.00
OHu24803	NM_139010.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu24911	NM_139003.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu24959	NM_139008.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu24974	NM_139004.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu25027	NM_139009.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu25063	NM_139007.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu40281	NM_001300749.2 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant 12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu58198	XM_011514543.3 Latest version!	Homo sapiens homeostatic iron regulator (HFE), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu24974	NM_139004.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu24803	NM_139010.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu24713	NM_139011.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu24786	NM_139006.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$195.30 $279.00
OHu24959	NM_139008.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu24911	NM_139003.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu25027	NM_139009.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu58198	XM_011514543.2	Homo sapiens hemochromatosis (HFE), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu25063	NM_139007.2	Homo sapiens homeostatic iron regulator (HFE), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu40281	NM_001300749.1	Homo sapiens homeostatic iron regulator (HFE), transcript variant 12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

HFE ( NM_000410.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000401.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24991
Clone ID Related Accession (Same CDS sequence)	NM_000410.3
Accession Version	NM_000410.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249337.1, AF115265.1 and U91328.1. This sequence is a reference standard in the RefSeqGene project. On Apr 10, 2006 this sequence version replaced NM_000410.2. Transcript Variant: This variant (1) encodes the longest isoform. CCDS Note: This CCDS ID represents the longest isoform encoded by the HFE gene. This isoform contains both a Class I Histocompatibility antigen (MHC_I) and an Immunoglobulin constant region (IGc) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.105052.1, SRR1660807.164609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000401.1
CDS	161..1207
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_000410.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000410.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139011.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620580.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 11, mRNA.

Price & Availability↑

CloneID	OHu24713
Clone ID Related Accession (Same CDS sequence)	NM_139011.3 , NM_139011.2
Accession Version	NM_139011.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 11 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249338.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139011.2. Transcript Variant: This variant (11) lacks a large internal part of the coding region but the reading frame is maintained, as compared to variant 1. The protein encoded is the shortest isoform (11). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks three internal coding exons compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that lacks both the Class I Histocompatibility antigen (MHC_I) and Immunoglobulin constant region (IGc) domains. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA996319.1, AJ249338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620580.1
CDS	13..243
Translation	MGPRARPALLLLMLLQTAVLQGRLLQPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139011.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139011.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139011.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620580.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 11, mRNA.

Price & Availability↑

CloneID	OHu24713
Clone ID Related Accession (Same CDS sequence)	NM_139011.3 , NM_139011.2
Accession Version	NM_139011.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 11 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249338.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139011.1. Transcript Variant: This variant (11) lacks a large internal part of the coding region but the reading frame is maintained, as compared to variant 1. The protein encoded is the shortest isoform (11). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks three internal coding exons compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that lacks both the Class I Histocompatibility antigen (MHC_I) and Immunoglobulin constant region (IGc) domains. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ249338.1, DA996319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620580.1
CDS	161..391
Translation	MGPRARPALLLLMLLQTAVLQGRLLQPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139011.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139011.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139006.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620575.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu24786
Clone ID Related Accession (Same CDS sequence)	NM_139006.3 , NM_139006.2
Accession Version	NM_139006.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 6 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF079407.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139006.2. Transcript Variant: This variant (6) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 6). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF079407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2155628 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGAC CACTCTACGG TGTCGGGCCT TGAACTACTA CCCCCAGAAC 
ATCACCATGA AGTGGCTGAA GGATAAGCAG CCAATGGATG CCAAGGAGTT CGAACCTAAA 
GACGTATTGC CCAATGGGGA TGGGACCTAC CAGGGCTGGA TAACCTTGGC TGTACCCCCT 
GGGGAAGAGC AGAGATATAC GTGCCAGGTG GAGCACCCAG GCCTGGATCA GCCCCTCATT 
GTGATCTGGG AGCCCTCACC GTCTGGCACC CTAGTCATTG GAGTCATCAG TGGAATTGCT 
GTTTTTGTCG TCATCTTGTT CATTGGAATT TTGTTCATAA TATTAAGGAA GAGGCAGGGT 
TCAAGAGGAG CCATGGGGCA CTACGTCTTA GCTGAACGTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620575.1
CDS	13..1017
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139006.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139006.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGAC CACTCTACGG TGTCGGGCCT TGAACTACTA CCCCCAGAAC 
ATCACCATGA AGTGGCTGAA GGATAAGCAG CCAATGGATG CCAAGGAGTT CGAACCTAAA 
GACGTATTGC CCAATGGGGA TGGGACCTAC CAGGGCTGGA TAACCTTGGC TGTACCCCCT 
GGGGAAGAGC AGAGATATAC GTGCCAGGTG GAGCACCCAG GCCTGGATCA GCCCCTCATT 
GTGATCTGGG AGCCCTCACC GTCTGGCACC CTAGTCATTG GAGTCATCAG TGGAATTGCT 
GTTTTTGTCG TCATCTTGTT CATTGGAATT TTGTTCATAA TATTAAGGAA GAGGCAGGGT 
TCAAGAGGAG CCATGGGGCA CTACGTCTTA GCTGAACGTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139006.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620575.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu24786
Clone ID Related Accession (Same CDS sequence)	NM_139006.3 , NM_139006.2
Accession Version	NM_139006.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 6 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249335.1, AF079407.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139006.1. Transcript Variant: This variant (6) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 6). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF079407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2155628 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGAC CACTCTACGG TGTCGGGCCT TGAACTACTA CCCCCAGAAC 
ATCACCATGA AGTGGCTGAA GGATAAGCAG CCAATGGATG CCAAGGAGTT CGAACCTAAA 
GACGTATTGC CCAATGGGGA TGGGACCTAC CAGGGCTGGA TAACCTTGGC TGTACCCCCT 
GGGGAAGAGC AGAGATATAC GTGCCAGGTG GAGCACCCAG GCCTGGATCA GCCCCTCATT 
GTGATCTGGG AGCCCTCACC GTCTGGCACC CTAGTCATTG GAGTCATCAG TGGAATTGCT 
GTTTTTGTCG TCATCTTGTT CATTGGAATT TTGTTCATAA TATTAAGGAA GAGGCAGGGT 
TCAAGAGGAG CCATGGGGCA CTACGTCTTA GCTGAACGTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620575.1
CDS	161..1165
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139006.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139006.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGAC CACTCTACGG TGTCGGGCCT TGAACTACTA CCCCCAGAAC 
ATCACCATGA AGTGGCTGAA GGATAAGCAG CCAATGGATG CCAAGGAGTT CGAACCTAAA 
GACGTATTGC CCAATGGGGA TGGGACCTAC CAGGGCTGGA TAACCTTGGC TGTACCCCCT 
GGGGAAGAGC AGAGATATAC GTGCCAGGTG GAGCACCCAG GCCTGGATCA GCCCCTCATT 
GTGATCTGGG AGCCCTCACC GTCTGGCACC CTAGTCATTG GAGTCATCAG TGGAATTGCT 
GTTTTTGTCG TCATCTTGTT CATTGGAATT TTGTTCATAA TATTAAGGAA GAGGCAGGGT 
TCAAGAGGAG CCATGGGGCA CTACGTCTTA GCTGAACGTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139010.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620579.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 10, mRNA.

Price & Availability↑

CloneID	OHu24803
Clone ID Related Accession (Same CDS sequence)	NM_139010.3 , NM_139010.2
Accession Version	NM_139010.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 10 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ250635.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139010.2. Transcript Variant: This variant (10) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 10). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks two internal coding exons compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that lacks the entire Class I Histocompatibility antigen (MHC_I) domain, but the Immunoglobulin constant region (IGc) domain is included. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.506667.1, AJ250635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620579.1
CDS	13..519
Translation	MGPRARPALLLLMLLQTAVLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139010.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139010.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139010.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620579.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 10, mRNA.

Price & Availability↑

CloneID	OHu24803
Clone ID Related Accession (Same CDS sequence)	NM_139010.3 , NM_139010.2
Accession Version	NM_139010.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 10 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ250635.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139010.1. Transcript Variant: This variant (10) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 10). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks two internal coding exons compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that lacks the entire Class I Histocompatibility antigen (MHC_I) domain, but the Immunoglobulin constant region (IGc) domain is included. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ250635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620579.1
CDS	161..667
Translation	MGPRARPALLLLMLLQTAVLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139010.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139010.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139003.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620572.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu24911
Clone ID Related Accession (Same CDS sequence)	NM_139003.2 , NM_139003.3
Accession Version	NM_139003.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249335.1, AF149804.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139003.1. Transcript Variant: This variant (3) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF149804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465414 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGACCACTCT ACGGTGTCGG 
GCCTTGAACT ACTACCCCCA GAACATCACC ATGAAGTGGC TGAAGGATAA GCAGCCAATG 
GATGCCAAGG AGTTCGAACC TAAAGACGTA TTGCCCAATG GGGATGGGAC CTACCAGGGC 
TGGATAACCT TGGCTGTACC CCCTGGGGAA GAGCAGAGAT ATACGTGCCA GGTGGAGCAC 
CCAGGCCTGG ATCAGCCCCT CATTGTGATC TGGGAGCCCT CACCGTCTGG CACCCTAGTC 
ATTGGAGTCA TCAGTGGAAT TGCTGTTTTT GTCGTCATCT TGTTCATTGG AATTTTGTTC 
ATAATATTAA GGAAGAGGCA GGGTTCAAGA GGAGCCATGG GGCACTACGT CTTAGCTGAA 
CGTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620572.1
CDS	161..889
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139003.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139003.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGACCACTCT ACGGTGTCGG 
GCCTTGAACT ACTACCCCCA GAACATCACC ATGAAGTGGC TGAAGGATAA GCAGCCAATG 
GATGCCAAGG AGTTCGAACC TAAAGACGTA TTGCCCAATG GGGATGGGAC CTACCAGGGC 
TGGATAACCT TGGCTGTACC CCCTGGGGAA GAGCAGAGAT ATACGTGCCA GGTGGAGCAC 
CCAGGCCTGG ATCAGCCCCT CATTGTGATC TGGGAGCCCT CACCGTCTGG CACCCTAGTC 
ATTGGAGTCA TCAGTGGAAT TGCTGTTTTT GTCGTCATCT TGTTCATTGG AATTTTGTTC 
ATAATATTAA GGAAGAGGCA GGGTTCAAGA GGAGCCATGG GGCACTACGT CTTAGCTGAA 
CGTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139003.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620572.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu24911
Clone ID Related Accession (Same CDS sequence)	NM_139003.2 , NM_139003.3
Accession Version	NM_139003.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249335.1, AF149804.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139003.2. Transcript Variant: This variant (3) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF149804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465414 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGACCACTCT ACGGTGTCGG 
GCCTTGAACT ACTACCCCCA GAACATCACC ATGAAGTGGC TGAAGGATAA GCAGCCAATG 
GATGCCAAGG AGTTCGAACC TAAAGACGTA TTGCCCAATG GGGATGGGAC CTACCAGGGC 
TGGATAACCT TGGCTGTACC CCCTGGGGAA GAGCAGAGAT ATACGTGCCA GGTGGAGCAC 
CCAGGCCTGG ATCAGCCCCT CATTGTGATC TGGGAGCCCT CACCGTCTGG CACCCTAGTC 
ATTGGAGTCA TCAGTGGAAT TGCTGTTTTT GTCGTCATCT TGTTCATTGG AATTTTGTTC 
ATAATATTAA GGAAGAGGCA GGGTTCAAGA GGAGCCATGG GGCACTACGT CTTAGCTGAA 
CGTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620572.1
CDS	13..741
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139003.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139003.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGACCACTCT ACGGTGTCGG 
GCCTTGAACT ACTACCCCCA GAACATCACC ATGAAGTGGC TGAAGGATAA GCAGCCAATG 
GATGCCAAGG AGTTCGAACC TAAAGACGTA TTGCCCAATG GGGATGGGAC CTACCAGGGC 
TGGATAACCT TGGCTGTACC CCCTGGGGAA GAGCAGAGAT ATACGTGCCA GGTGGAGCAC 
CCAGGCCTGG ATCAGCCCCT CATTGTGATC TGGGAGCCCT CACCGTCTGG CACCCTAGTC 
ATTGGAGTCA TCAGTGGAAT TGCTGTTTTT GTCGTCATCT TGTTCATTGG AATTTTGTTC 
ATAATATTAA GGAAGAGGCA GGGTTCAAGA GGAGCCATGG GGCACTACGT CTTAGCTGAA 
CGTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139008.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620577.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu24959
Clone ID Related Accession (Same CDS sequence)	NM_139008.2 , NM_139008.3
Accession Version	NM_139008.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 8 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249335.1, AF079409.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139008.1. Transcript Variant: This variant (8) lacks two internal in-frame segments of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 8). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF079409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155628, SAMEA2159080 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGACCACT 
CTACGGTGTC GGGCCTTGAA CTACTACCCC CAGAACATCA CCATGAAGTG GCTGAAGGAT 
AAGCAGCCAA TGGATGCCAA GGAGTTCGAA CCTAAAGACG TATTGCCCAA TGGGGATGGG 
ACCTACCAGG GCTGGATAAC CTTGGCTGTA CCCCCTGGGG AAGAGCAGAG ATATACGTGC 
CAGGTGGAGC ACCCAGGCCT GGATCAGCCC CTCATTGTGA TCTGGGAGCC CTCACCGTCT 
GGCACCCTAG TCATTGGAGT CATCAGTGGA ATTGCTGTTT TTGTCGTCAT CTTGTTCATT 
GGAATTTTGT TCATAATATT AAGGAAGAGG CAGGGTTCAA GAGGAGCCAT GGGGCACTAC 
GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620577.1
CDS	161..901
Translation	MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139008.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139008.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGACCACT 
CTACGGTGTC GGGCCTTGAA CTACTACCCC CAGAACATCA CCATGAAGTG GCTGAAGGAT 
AAGCAGCCAA TGGATGCCAA GGAGTTCGAA CCTAAAGACG TATTGCCCAA TGGGGATGGG 
ACCTACCAGG GCTGGATAAC CTTGGCTGTA CCCCCTGGGG AAGAGCAGAG ATATACGTGC 
CAGGTGGAGC ACCCAGGCCT GGATCAGCCC CTCATTGTGA TCTGGGAGCC CTCACCGTCT 
GGCACCCTAG TCATTGGAGT CATCAGTGGA ATTGCTGTTT TTGTCGTCAT CTTGTTCATT 
GGAATTTTGT TCATAATATT AAGGAAGAGG CAGGGTTCAA GAGGAGCCAT GGGGCACTAC 
GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139008.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620577.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu24959
Clone ID Related Accession (Same CDS sequence)	NM_139008.2 , NM_139008.3
Accession Version	NM_139008.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 8 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF079409.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139008.2. Transcript Variant: This variant (8) lacks two internal in-frame segments of the coding region, as compared to variant 1, resulting in a shorter protein (isoform 8). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF079409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155628, SAMEA2159080 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGACCACT 
CTACGGTGTC GGGCCTTGAA CTACTACCCC CAGAACATCA CCATGAAGTG GCTGAAGGAT 
AAGCAGCCAA TGGATGCCAA GGAGTTCGAA CCTAAAGACG TATTGCCCAA TGGGGATGGG 
ACCTACCAGG GCTGGATAAC CTTGGCTGTA CCCCCTGGGG AAGAGCAGAG ATATACGTGC 
CAGGTGGAGC ACCCAGGCCT GGATCAGCCC CTCATTGTGA TCTGGGAGCC CTCACCGTCT 
GGCACCCTAG TCATTGGAGT CATCAGTGGA ATTGCTGTTT TTGTCGTCAT CTTGTTCATT 
GGAATTTTGT TCATAATATT AAGGAAGAGG CAGGGTTCAA GAGGAGCCAT GGGGCACTAC 
GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620577.1
CDS	13..753
Translation	MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139008.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139008.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGACCACT 
CTACGGTGTC GGGCCTTGAA CTACTACCCC CAGAACATCA CCATGAAGTG GCTGAAGGAT 
AAGCAGCCAA TGGATGCCAA GGAGTTCGAA CCTAAAGACG TATTGCCCAA TGGGGATGGG 
ACCTACCAGG GCTGGATAAC CTTGGCTGTA CCCCCTGGGG AAGAGCAGAG ATATACGTGC 
CAGGTGGAGC ACCCAGGCCT GGATCAGCCC CTCATTGTGA TCTGGGAGCC CTCACCGTCT 
GGCACCCTAG TCATTGGAGT CATCAGTGGA ATTGCTGTTT TTGTCGTCAT CTTGTTCATT 
GGAATTTTGT TCATAATATT AAGGAAGAGG CAGGGTTCAA GAGGAGCCAT GGGGCACTAC 
GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139004.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620573.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu24974
Clone ID Related Accession (Same CDS sequence)	NM_139004.3 , NM_139004.2
Accession Version	NM_139004.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249337.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139004.2. Transcript Variant: This variant (4) lacks an internal in-frame segment of the coding region, compared to variant 1, resulting in a shorter protein (isoform 4). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks an internal coding exon compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that includes the Immunoglobulin constant region (IGc) domain but lacks a portion of the Class I Histocompatibility antigen (MHC_I) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF144242.1, AJ249337.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGCCTCCTTT GGTGAAGGTG 
ACACATCATG TGACCTCTTC AGTGACCACT CTACGGTGTC GGGCCTTGAA CTACTACCCC 
CAGAACATCA CCATGAAGTG GCTGAAGGAT AAGCAGCCAA TGGATGCCAA GGAGTTCGAA 
CCTAAAGACG TATTGCCCAA TGGGGATGGG ACCTACCAGG GCTGGATAAC CTTGGCTGTA 
CCCCCTGGGG AAGAGCAGAG ATATACGTGC CAGGTGGAGC ACCCAGGCCT GGATCAGCCC 
CTCATTGTGA TCTGGGAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620573.1
CDS	13..783
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139004.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139004.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGCCTCCTTT GGTGAAGGTG 
ACACATCATG TGACCTCTTC AGTGACCACT CTACGGTGTC GGGCCTTGAA CTACTACCCC 
CAGAACATCA CCATGAAGTG GCTGAAGGAT AAGCAGCCAA TGGATGCCAA GGAGTTCGAA 
CCTAAAGACG TATTGCCCAA TGGGGATGGG ACCTACCAGG GCTGGATAAC CTTGGCTGTA 
CCCCCTGGGG AAGAGCAGAG ATATACGTGC CAGGTGGAGC ACCCAGGCCT GGATCAGCCC 
CTCATTGTGA TCTGGGAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139004.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620573.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu24974
Clone ID Related Accession (Same CDS sequence)	NM_139004.3 , NM_139004.2
Accession Version	NM_139004.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249337.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139004.1. Transcript Variant: This variant (4) lacks an internal in-frame segment of the coding region, compared to variant 1, resulting in a shorter protein (isoform 4). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks an internal coding exon compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that includes the Immunoglobulin constant region (IGc) domain but lacks a portion of the Class I Histocompatibility antigen (MHC_I) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ249337.1, AF144242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGCCTCCTTT GGTGAAGGTG 
ACACATCATG TGACCTCTTC AGTGACCACT CTACGGTGTC GGGCCTTGAA CTACTACCCC 
CAGAACATCA CCATGAAGTG GCTGAAGGAT AAGCAGCCAA TGGATGCCAA GGAGTTCGAA 
CCTAAAGACG TATTGCCCAA TGGGGATGGG ACCTACCAGG GCTGGATAAC CTTGGCTGTA 
CCCCCTGGGG AAGAGCAGAG ATATACGTGC CAGGTGGAGC ACCCAGGCCT GGATCAGCCC 
CTCATTGTGA TCTGGGAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620573.1
CDS	161..931
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139004.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139004.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG TGCCTCCTTT GGTGAAGGTG 
ACACATCATG TGACCTCTTC AGTGACCACT CTACGGTGTC GGGCCTTGAA CTACTACCCC 
CAGAACATCA CCATGAAGTG GCTGAAGGAT AAGCAGCCAA TGGATGCCAA GGAGTTCGAA 
CCTAAAGACG TATTGCCCAA TGGGGATGGG ACCTACCAGG GCTGGATAAC CTTGGCTGTA 
CCCCCTGGGG AAGAGCAGAG ATATACGTGC CAGGTGGAGC ACCCAGGCCT GGATCAGCCC 
CTCATTGTGA TCTGGGAGCC CTCACCGTCT GGCACCCTAG TCATTGGAGT CATCAGTGGA 
ATTGCTGTTT TTGTCGTCAT CTTGTTCATT GGAATTTTGT TCATAATATT AAGGAAGAGG 
CAGGGTTCAA GAGGAGCCAT GGGGCACTAC GTCTTAGCTG AACGTGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139009.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620578.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu25027
Clone ID Related Accession (Same CDS sequence)	NM_139009.2 , NM_139009.3
Accession Version	NM_139009.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 9 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249335.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139009.1. Transcript Variant: This variant (9) lacks an internal in-frame segment of the coding region through the use of an alternate splice acceptor site, as compared to variant 1, resulting in a shorter protein (isoform 9). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ249335.1 [ECO:0000332] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCCTTT GGGCTACGTG GATGACCAGC TGTTCGTGTT CTATGATCAT 
GAGAGTCGCC GTGTGGAGCC CCGAACTCCA TGGGTTTCCA GTAGAATTTC AAGCCAGATG 
TGGCTGCAGC TGAGTCAGAG TCTGAAAGGG TGGGATCACA TGTTCACTGT TGACTTCTGG 
ACTATTATGG AAAATCACAA CCACAGCAAG GAGTCCCACA CCCTGCAGGT CATCCTGGGC 
TGTGAAATGC AAGAAGACAA CAGTACCGAG GGCTACTGGA AGTACGGGTA TGATGGGCAG 
GACCACCTTG AATTCTGCCC TGACACACTG GATTGGAGAG CAGCAGAACC CAGGGCCTGG 
CCCACCAAGC TGGAGTGGGA AAGGCACAAG ATTCGGGCCA GGCAGAACAG GGCCTACCTG 
GAGAGGGACT GCCCTGCACA GCTGCAGCAG TTGCTGGAGC TGGGGAGAGG TGTTTTGGAC 
CAACAAGTGC CTCCTTTGGT GAAGGTGACA CATCATGTGA CCTCTTCAGT GACCACTCTA 
CGGTGTCGGG CCTTGAACTA CTACCCCCAG AACATCACCA TGAAGTGGCT GAAGGATAAG 
CAGCCAATGG ATGCCAAGGA GTTCGAACCT AAAGACGTAT TGCCCAATGG GGATGGGACC 
TACCAGGGCT GGATAACCTT GGCTGTACCC CCTGGGGAAG AGCAGAGATA TACGTGCCAG 
GTGGAGCACC CAGGCCTGGA TCAGCCCCTC ATTGTGATCT GGGAGCCCTC ACCGTCTGGC 
ACCCTAGTCA TTGGAGTCAT CAGTGGAATT GCTGTTTTTG TCGTCATCTT GTTCATTGGA 
ATTTTGTTCA TAATATTAAG GAAGAGGCAG GGTTCAAGAG GAGCCATGGG GCACTACGTC 
TTAGCTGAAC GTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620578.1
CDS	161..1138
Translation	MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139009.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139009.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCCTTT GGGCTACGTG GATGACCAGC TGTTCGTGTT CTATGATCAT 
GAGAGTCGCC GTGTGGAGCC CCGAACTCCA TGGGTTTCCA GTAGAATTTC AAGCCAGATG 
TGGCTGCAGC TGAGTCAGAG TCTGAAAGGG TGGGATCACA TGTTCACTGT TGACTTCTGG 
ACTATTATGG AAAATCACAA CCACAGCAAG GAGTCCCACA CCCTGCAGGT CATCCTGGGC 
TGTGAAATGC AAGAAGACAA CAGTACCGAG GGCTACTGGA AGTACGGGTA TGATGGGCAG 
GACCACCTTG AATTCTGCCC TGACACACTG GATTGGAGAG CAGCAGAACC CAGGGCCTGG 
CCCACCAAGC TGGAGTGGGA AAGGCACAAG ATTCGGGCCA GGCAGAACAG GGCCTACCTG 
GAGAGGGACT GCCCTGCACA GCTGCAGCAG TTGCTGGAGC TGGGGAGAGG TGTTTTGGAC 
CAACAAGTGC CTCCTTTGGT GAAGGTGACA CATCATGTGA CCTCTTCAGT GACCACTCTA 
CGGTGTCGGG CCTTGAACTA CTACCCCCAG AACATCACCA TGAAGTGGCT GAAGGATAAG 
CAGCCAATGG ATGCCAAGGA GTTCGAACCT AAAGACGTAT TGCCCAATGG GGATGGGACC 
TACCAGGGCT GGATAACCTT GGCTGTACCC CCTGGGGAAG AGCAGAGATA TACGTGCCAG 
GTGGAGCACC CAGGCCTGGA TCAGCCCCTC ATTGTGATCT GGGAGCCCTC ACCGTCTGGC 
ACCCTAGTCA TTGGAGTCAT CAGTGGAATT GCTGTTTTTG TCGTCATCTT GTTCATTGGA 
ATTTTGTTCA TAATATTAAG GAAGAGGCAG GGTTCAAGAG GAGCCATGGG GCACTACGTC 
TTAGCTGAAC GTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139009.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620578.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu25027
Clone ID Related Accession (Same CDS sequence)	NM_139009.2 , NM_139009.3
Accession Version	NM_139009.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 9 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249335.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139009.2. Transcript Variant: This variant (9) lacks an internal in-frame segment of the coding region through the use of an alternate splice acceptor site, as compared to variant 1, resulting in a shorter protein (isoform 9). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ249335.1 [ECO:0000332] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCCTTT GGGCTACGTG GATGACCAGC TGTTCGTGTT CTATGATCAT 
GAGAGTCGCC GTGTGGAGCC CCGAACTCCA TGGGTTTCCA GTAGAATTTC AAGCCAGATG 
TGGCTGCAGC TGAGTCAGAG TCTGAAAGGG TGGGATCACA TGTTCACTGT TGACTTCTGG 
ACTATTATGG AAAATCACAA CCACAGCAAG GAGTCCCACA CCCTGCAGGT CATCCTGGGC 
TGTGAAATGC AAGAAGACAA CAGTACCGAG GGCTACTGGA AGTACGGGTA TGATGGGCAG 
GACCACCTTG AATTCTGCCC TGACACACTG GATTGGAGAG CAGCAGAACC CAGGGCCTGG 
CCCACCAAGC TGGAGTGGGA AAGGCACAAG ATTCGGGCCA GGCAGAACAG GGCCTACCTG 
GAGAGGGACT GCCCTGCACA GCTGCAGCAG TTGCTGGAGC TGGGGAGAGG TGTTTTGGAC 
CAACAAGTGC CTCCTTTGGT GAAGGTGACA CATCATGTGA CCTCTTCAGT GACCACTCTA 
CGGTGTCGGG CCTTGAACTA CTACCCCCAG AACATCACCA TGAAGTGGCT GAAGGATAAG 
CAGCCAATGG ATGCCAAGGA GTTCGAACCT AAAGACGTAT TGCCCAATGG GGATGGGACC 
TACCAGGGCT GGATAACCTT GGCTGTACCC CCTGGGGAAG AGCAGAGATA TACGTGCCAG 
GTGGAGCACC CAGGCCTGGA TCAGCCCCTC ATTGTGATCT GGGAGCCCTC ACCGTCTGGC 
ACCCTAGTCA TTGGAGTCAT CAGTGGAATT GCTGTTTTTG TCGTCATCTT GTTCATTGGA 
ATTTTGTTCA TAATATTAAG GAAGAGGCAG GGTTCAAGAG GAGCCATGGG GCACTACGTC 
TTAGCTGAAC GTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620578.1
CDS	13..990
Translation	MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139009.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139009.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCCTTT GGGCTACGTG GATGACCAGC TGTTCGTGTT CTATGATCAT 
GAGAGTCGCC GTGTGGAGCC CCGAACTCCA TGGGTTTCCA GTAGAATTTC AAGCCAGATG 
TGGCTGCAGC TGAGTCAGAG TCTGAAAGGG TGGGATCACA TGTTCACTGT TGACTTCTGG 
ACTATTATGG AAAATCACAA CCACAGCAAG GAGTCCCACA CCCTGCAGGT CATCCTGGGC 
TGTGAAATGC AAGAAGACAA CAGTACCGAG GGCTACTGGA AGTACGGGTA TGATGGGCAG 
GACCACCTTG AATTCTGCCC TGACACACTG GATTGGAGAG CAGCAGAACC CAGGGCCTGG 
CCCACCAAGC TGGAGTGGGA AAGGCACAAG ATTCGGGCCA GGCAGAACAG GGCCTACCTG 
GAGAGGGACT GCCCTGCACA GCTGCAGCAG TTGCTGGAGC TGGGGAGAGG TGTTTTGGAC 
CAACAAGTGC CTCCTTTGGT GAAGGTGACA CATCATGTGA CCTCTTCAGT GACCACTCTA 
CGGTGTCGGG CCTTGAACTA CTACCCCCAG AACATCACCA TGAAGTGGCT GAAGGATAAG 
CAGCCAATGG ATGCCAAGGA GTTCGAACCT AAAGACGTAT TGCCCAATGG GGATGGGACC 
TACCAGGGCT GGATAACCTT GGCTGTACCC CCTGGGGAAG AGCAGAGATA TACGTGCCAG 
GTGGAGCACC CAGGCCTGGA TCAGCCCCTC ATTGTGATCT GGGAGCCCTC ACCGTCTGGC 
ACCCTAGTCA TTGGAGTCAT CAGTGGAATT GCTGTTTTTG TCGTCATCTT GTTCATTGGA 
ATTTTGTTCA TAATATTAAG GAAGAGGCAG GGTTCAAGAG GAGCCATGGG GCACTACGTC 
TTAGCTGAAC GTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139007.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_620576.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu25063
Clone ID Related Accession (Same CDS sequence)	NM_139007.2 , NM_139007.3
Accession Version	NM_139007.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 7 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249336.1 and U91328.1. On Apr 10, 2006 this sequence version replaced NM_139007.1. Transcript Variant: This variant (7) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein isoform (7). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks an internal coding exon compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that includes the Immunoglobulin constant region (IGc) domain but lacks a portion of the Class I Histocompatibility antigen (MHC_I) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ249336.1, BC143887.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGCCTCCT 
TTGGTGAAGG TGACACATCA TGTGACCTCT TCAGTGACCA CTCTACGGTG TCGGGCCTTG 
AACTACTACC CCCAGAACAT CACCATGAAG TGGCTGAAGG ATAAGCAGCC AATGGATGCC 
AAGGAGTTCG AACCTAAAGA CGTATTGCCC AATGGGGATG GGACCTACCA GGGCTGGATA 
ACCTTGGCTG TACCCCCTGG GGAAGAGCAG AGATATACGT GCCAGGTGGA GCACCCAGGC 
CTGGATCAGC CCCTCATTGT GATCTGGGAG CCCTCACCGT CTGGCACCCT AGTCATTGGA 
GTCATCAGTG GAATTGCTGT TTTTGTCGTC ATCTTGTTCA TTGGAATTTT GTTCATAATA 
TTAAGGAAGA GGCAGGGTTC AAGAGGAGCC ATGGGGCACT ACGTCTTAGC TGAACGTGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620576.1
CDS	161..943
Translation	MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139007.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139007.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGCCTCCT 
TTGGTGAAGG TGACACATCA TGTGACCTCT TCAGTGACCA CTCTACGGTG TCGGGCCTTG 
AACTACTACC CCCAGAACAT CACCATGAAG TGGCTGAAGG ATAAGCAGCC AATGGATGCC 
AAGGAGTTCG AACCTAAAGA CGTATTGCCC AATGGGGATG GGACCTACCA GGGCTGGATA 
ACCTTGGCTG TACCCCCTGG GGAAGAGCAG AGATATACGT GCCAGGTGGA GCACCCAGGC 
CTGGATCAGC CCCTCATTGT GATCTGGGAG CCCTCACCGT CTGGCACCCT AGTCATTGGA 
GTCATCAGTG GAATTGCTGT TTTTGTCGTC ATCTTGTTCA TTGGAATTTT GTTCATAATA 
TTAAGGAAGA GGCAGGGTTC AAGAGGAGCC ATGGGGCACT ACGTCTTAGC TGAACGTGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_139007.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620576.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu25063
Clone ID Related Accession (Same CDS sequence)	NM_139007.2 , NM_139007.3
Accession Version	NM_139007.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 7 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249336.1 and U91328.1. On Jun 2, 2019 this sequence version replaced NM_139007.2. Transcript Variant: This variant (7) lacks an internal in-frame segment of the coding region, as compared to variant 1, resulting in a shorter protein isoform (7). CCDS Note: This CCDS ID represents a variant of the HFE gene that lacks an internal coding exon compared to the longest variant, which is represented by CCDS4578.1. This results in an isoform that includes the Immunoglobulin constant region (IGc) domain but lacks a portion of the Class I Histocompatibility antigen (MHC_I) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.419770.1, BC143887.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGCCTCCT 
TTGGTGAAGG TGACACATCA TGTGACCTCT TCAGTGACCA CTCTACGGTG TCGGGCCTTG 
AACTACTACC CCCAGAACAT CACCATGAAG TGGCTGAAGG ATAAGCAGCC AATGGATGCC 
AAGGAGTTCG AACCTAAAGA CGTATTGCCC AATGGGGATG GGACCTACCA GGGCTGGATA 
ACCTTGGCTG TACCCCCTGG GGAAGAGCAG AGATATACGT GCCAGGTGGA GCACCCAGGC 
CTGGATCAGC CCCTCATTGT GATCTGGGAG CCCTCACCGT CTGGCACCCT AGTCATTGGA 
GTCATCAGTG GAATTGCTGT TTTTGTCGTC ATCTTGTTCA TTGGAATTTT GTTCATAATA 
TTAAGGAAGA GGCAGGGTTC AAGAGGAGCC ATGGGGCACT ACGTCTTAGC TGAACGTGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620576.1
CDS	13..795
Translation	MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Target ORF information:

RefSeq Version	NM_139007.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139007.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCAGTC CCACACCCTG CAGGTCATCC TGGGCTGTGA AATGCAAGAA 
GACAACAGTA CCGAGGGCTA CTGGAAGTAC GGGTATGATG GGCAGGACCA CCTTGAATTC 
TGCCCTGACA CACTGGATTG GAGAGCAGCA GAACCCAGGG CCTGGCCCAC CAAGCTGGAG 
TGGGAAAGGC ACAAGATTCG GGCCAGGCAG AACAGGGCCT ACCTGGAGAG GGACTGCCCT 
GCACAGCTGC AGCAGTTGCT GGAGCTGGGG AGAGGTGTTT TGGACCAACA AGTGCCTCCT 
TTGGTGAAGG TGACACATCA TGTGACCTCT TCAGTGACCA CTCTACGGTG TCGGGCCTTG 
AACTACTACC CCCAGAACAT CACCATGAAG TGGCTGAAGG ATAAGCAGCC AATGGATGCC 
AAGGAGTTCG AACCTAAAGA CGTATTGCCC AATGGGGATG GGACCTACCA GGGCTGGATA 
ACCTTGGCTG TACCCCCTGG GGAAGAGCAG AGATATACGT GCCAGGTGGA GCACCCAGGC 
CTGGATCAGC CCCTCATTGT GATCTGGGAG CCCTCACCGT CTGGCACCCT AGTCATTGGA 
GTCATCAGTG GAATTGCTGT TTTTGTCGTC ATCTTGTTCA TTGGAATTTT GTTCATAATA 
TTAAGGAAGA GGCAGGGTTC AAGAGGAGCC ATGGGGCACT ACGTCTTAGC TGAACGTGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_001300749.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287678.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 12, mRNA.

Price & Availability↑

CloneID	OHu40281
Clone ID Related Accession (Same CDS sequence)	NM_001300749.1 , NM_001300749.2
Accession Version	NM_001300749.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 12 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249337.1, AK300933.1, BC117201.1 and AJ298840.1. On Jul 11, 2014 this sequence version replaced XM_006715075.1. Transcript Variant: This variant (12) uses an alternate splice acceptor site at its 3'-terminal exon, compared to variant 1. This variant encodes isoform 12 which has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300933.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGTTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287678.1
CDS	161..1174
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSSF

Target ORF information:

RefSeq Version	NM_001300749.1
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300749.1

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGTTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( NM_001300749.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287678.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant 12, mRNA.

Price & Availability↑

CloneID	OHu40281
Clone ID Related Accession (Same CDS sequence)	NM_001300749.1 , NM_001300749.2
Accession Version	NM_001300749.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform 12 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ249337.1, AK300933.1, BC117201.1 and AJ298840.1. On Jun 2, 2019 this sequence version replaced NM_001300749.1. Transcript Variant: This variant (12) uses an alternate splice acceptor site at its 3'-terminal exon, compared to variant 1. This variant encodes isoform 12 which has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300933.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGTTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287678.1
CDS	13..1026
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSSF

Target ORF information:

RefSeq Version	NM_001300749.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant 12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300749.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGTTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( XM_011514543.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512845.1 Homo sapiens homeostatic iron regulator (HFE), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58198
Clone ID Related Accession (Same CDS sequence)	XM_011514543.3 , XM_011514543.2
Accession Version	XM_011514543.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011514543.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512845.1
CDS	95..1141
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERF

Target ORF information:

RefSeq Version	XM_011514543.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeostatic iron regulator (HFE), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514543.3

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HFE ( XM_011514543.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512845.1 Homo sapiens hemochromatosis (HFE), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58198
Clone ID Related Accession (Same CDS sequence)	XM_011514543.3 , XM_011514543.2
Accession Version	XM_011514543.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	hereditary hemochromatosis protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514543.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512845.1
CDS	123..1169
Translation	MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERF

Target ORF information:

RefSeq Version	XM_011514543.2
Organism	Homo sapiens(human)
Definition	Homo sapiens hemochromatosis (HFE), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514543.2

ORF Insert Sequence:

ATGGGCCCGC GAGCCAGGCC GGCGCTTCTC CTCCTGATGC TTTTGCAGAC CGCGGTCCTG 
CAGGGGCGCT TGCTGCGTTC ACACTCTCTG CACTACCTCT TCATGGGTGC CTCAGAGCAG 
GACCTTGGTC TTTCCTTGTT TGAAGCTTTG GGCTACGTGG ATGACCAGCT GTTCGTGTTC 
TATGATCATG AGAGTCGCCG TGTGGAGCCC CGAACTCCAT GGGTTTCCAG TAGAATTTCA 
AGCCAGATGT GGCTGCAGCT GAGTCAGAGT CTGAAAGGGT GGGATCACAT GTTCACTGTT 
GACTTCTGGA CTATTATGGA AAATCACAAC CACAGCAAGG AGTCCCACAC CCTGCAGGTC 
ATCCTGGGCT GTGAAATGCA AGAAGACAAC AGTACCGAGG GCTACTGGAA GTACGGGTAT 
GATGGGCAGG ACCACCTTGA ATTCTGCCCT GACACACTGG ATTGGAGAGC AGCAGAACCC 
AGGGCCTGGC CCACCAAGCT GGAGTGGGAA AGGCACAAGA TTCGGGCCAG GCAGAACAGG 
GCCTACCTGG AGAGGGACTG CCCTGCACAG CTGCAGCAGT TGCTGGAGCT GGGGAGAGGT 
GTTTTGGACC AACAAGTGCC TCCTTTGGTG AAGGTGACAC ATCATGTGAC CTCTTCAGTG 
ACCACTCTAC GGTGTCGGGC CTTGAACTAC TACCCCCAGA ACATCACCAT GAAGTGGCTG 
AAGGATAAGC AGCCAATGGA TGCCAAGGAG TTCGAACCTA AAGACGTATT GCCCAATGGG 
GATGGGACCT ACCAGGGCTG GATAACCTTG GCTGTACCCC CTGGGGAAGA GCAGAGATAT 
ACGTGCCAGG TGGAGCACCC AGGCCTGGAT CAGCCCCTCA TTGTGATCTG GGAGCCCTCA 
CCGTCTGGCA CCCTAGTCAT TGGAGTCATC AGTGGAATTG CTGTTTTTGT CGTCATCTTG 
TTCATTGGAA TTTTGTTCAT AATATTAAGG AAGAGGCAGG GTTCAAGAGG AGCCATGGGG 
CACTACGTCT TAGCTGAACG TTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	HFE
Entrez Gene ID	3077
Full Name	hemochromatosis
Synonyms	HFE1,HH,HLA-H,MVCD7,TFQTL2
General protein information	Preferred Names hemochromatosis Names hereditary hemochromatosis protein MHC class I-like protein HFE hereditary hemochromatosis protein HLA-H high Fe
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.2
Summary	The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	613609
Disorder Html:	Hemochromatosis, 235200 (3); {Microvascular complications of diabetes 7}, 612635 (3); {Porphyria variegata, susceptibility to}, 176200 (3); {Porphyria cutanea tarda, susceptibility to}, 176100 (3); {Alzheimer disease, susceptibility to}, 104300 (3); [Transferrin serum level QTL2], 614193 (3)

Mus musculus (house mouse)	Hfe	NP_034554.2
Pan troglodytes (chimpanzee)	HFE	NP_001009101.1
Canis lupus familiaris (dog)	HFE	XP_003434224.2
Homo sapiens (human)	HFE	NP_000401.1
	HFE	XP_001085245.2
Rattus norvegicus (Norway rat)	Hfe	NP_445753.1
Bos taurus (cattle)	HFE	NP_001012399.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

HFE cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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