ABT1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ABT1
Entrez Gene ID	29777
Full Name	activator of basal transcription 1
Synonyms	Esf2,hABT1
General protein information	Preferred Names activator of basal transcription 1 Names activator of basal transcription 1 TATA-binding protein-binding protein basal transcriptional activator
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.2
Summary	Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013375.3	NP_037507.1	activator of basal transcription 1
NM_013375.4	NP_037507.1	activator of basal transcription 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ABT1	NP_001069620.1
	ABT1	XP_001092231.2
Pan troglodytes (chimpanzee)	ABT1	XP_001173335.1
Mus musculus (house mouse)	Abt1	NP_038952.1
Rattus norvegicus (Norway rat)	Abt1	NP_001020845.1
Danio rerio (zebrafish)	abt1	NP_001018383.1
Homo sapiens (human)	ABT1	NP_037507.1
Canis lupus familiaris (dog)	ABT1	XP_003640216.1

Gene Ontology
Bibliography

Related articles in PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.
de Planell-Saguer M, Schroeder DG, Rodicio MC, Cox GA, Mourelatos Z
Human molecular genetics18(12)2115-26(2009 Jun)

Protein microarray analysis identifies human cellular prion protein interactors.
Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, Tabunoki H
Neuropathology and applied neurobiology35(1)16-35(2009 Feb)

Nucleolar proteome dynamics.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M
Nature433(7021)77-83(2005 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ABT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32333	NM_013375.4 Latest version!	Homo sapiens activator of basal transcription 1 (ABT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
View Old Accession Versions >>
OHu32333	NM_013375.3	Homo sapiens activator of basal transcription 1 (ABT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ABT1 ( NM_013375.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_037507.1 Homo sapiens activator of basal transcription 1 (ABT1), mRNA.

Price & Availability↑

CloneID	OHu32333
Clone ID Related Accession (Same CDS sequence)	NM_013375.3 , NM_013375.4
Accession Version	NM_013375.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 819bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	activator of basal transcription 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL513548.8. On May 3, 2011 this sequence version replaced NM_013375.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.207231.1, SRR1803612.188604.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCAG AGGAATCGGA GAAGGCCGCA ACGGAGCAAG AGCCGCTGGA AGGGACAGAA 
CAGACACTAG ATGCGGAGGA GGAGCAGGAG GAATCCGAAG AAGCGGCCTG TGGCAGCAAG 
AAACGGGTAG TGCCAGGTAT TGTGTACCTG GGCCATATCC CGCCGCGCTT CCGGCCCCTG 
CACGTCCGCA ACCTTCTCAG CGCCTATGGC GAGGTCGGAC GCGTCTTCTT TCAGGCTGAG 
GACCGGTTCG TGAGACGCAA GAAGAAGGCA GCAGCAGCTG CCGGAGGAAA AAAGCGGTCC 
TACACCAAGG ACTACACCGA GGGATGGGTG GAGTTCCGTG ACAAGCGCAT AGCCAAGCGC 
GTGGCGGCCA GTCTACACAA CACGCCTATG GGTGCCCGCA GGCGCAGCCC CTTCCGTTAT 
GATCTTTGGA ACCTCAAGTA CTTGCACCGT TTCACCTGGT CCCACCTCAG CGAGCACCTC 
GCCTTTGAGC GCCAGGTGCG CAGGCAGCGC TTGAGAGCGG AGGTTGCTCA AGCCAAGCGT 
GAGACCGACT TCTATCTTCA AAGTGTGGAA CGGGGACAAC GCTTTCTTGC GGCCGATGGG 
GACCCTGCTC GCCCAGATGG CTCCTGGACA TTTGCCCAGC GTCCTACTGA GCAGGAACTG 
AGGGCCCGTA AAGCAGCACG GCCAGGGGGA CGTGAACGGG CTCGCCTGGC AACTGCCCAG 
GACAAGGCCC GCTCCAACAA AGGGCTCCTG GCCAGGATCT TTGGAGCCCC GCCACCCTCA 
GAGAGCATGG AGGGACCTTC CCTTGTCAGG GACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037507.1
CDS	41..859
Translation	MEAEESEKAATEQEPLEGTEQTLDAEEEQEESEEAACGSKKRVVPGIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEDRFVRRKKKAAAAAGGKKRSYTKDYTEGWVEFRDKRIAKRVAASLHNTPMGARRRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLQSVERGQRFLAADGDPARPDGSWTFAQRPTEQELRARKAARPGGRERARLATAQDKARSNKGLLARIFGAPPPSESMEGPSLVRDS

Target ORF information:

RefSeq Version	NM_013375.3
Organism	Homo sapiens(human)
Definition	Homo sapiens activator of basal transcription 1 (ABT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013375.3

ORF Insert Sequence:

ATGGAGGCAG AGGAATCGGA GAAGGCCGCA ACGGAGCAAG AGCCGCTGGA AGGGACAGAA 
CAGACACTAG ATGCGGAGGA GGAGCAGGAG GAATCCGAAG AAGCGGCCTG TGGCAGCAAG 
AAACGGGTAG TGCCAGGTAT TGTGTACCTG GGCCATATCC CGCCGCGCTT CCGGCCCCTG 
CACGTCCGCA ACCTTCTCAG CGCCTATGGC GAGGTCGGAC GCGTCTTCTT TCAGGCTGAG 
GACCGGTTCG TGAGACGCAA GAAGAAGGCA GCAGCAGCTG CCGGAGGAAA AAAGCGGTCC 
TACACCAAGG ACTACACCGA GGGATGGGTG GAGTTCCGTG ACAAGCGCAT AGCCAAGCGC 
GTGGCGGCCA GTCTACACAA CACGCCTATG GGTGCCCGCA GGCGCAGCCC CTTCCGTTAT 
GATCTTTGGA ACCTCAAGTA CTTGCACCGT TTCACCTGGT CCCACCTCAG CGAGCACCTC 
GCCTTTGAGC GCCAGGTGCG CAGGCAGCGC TTGAGAGCGG AGGTTGCTCA AGCCAAGCGT 
GAGACCGACT TCTATCTTCA AAGTGTGGAA CGGGGACAAC GCTTTCTTGC GGCCGATGGG 
GACCCTGCTC GCCCAGATGG CTCCTGGACA TTTGCCCAGC GTCCTACTGA GCAGGAACTG 
AGGGCCCGTA AAGCAGCACG GCCAGGGGGA CGTGAACGGG CTCGCCTGGC AACTGCCCAG 
GACAAGGCCC GCTCCAACAA AGGGCTCCTG GCCAGGATCT TTGGAGCCCC GCCACCCTCA 
GAGAGCATGG AGGGACCTTC CCTTGTCAGG GACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABT1 ( NM_013375.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_037507.1 Homo sapiens activator of basal transcription 1 (ABT1), mRNA.

Price & Availability↑

CloneID	OHu32333
Clone ID Related Accession (Same CDS sequence)	NM_013375.3 , NM_013375.4
Accession Version	NM_013375.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 819bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	activator of basal transcription 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL513548.8. On Nov 23, 2018 this sequence version replaced NM_013375.3. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.268146.1, SRR1803612.188604.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000274849.3/ ENSP00000274849.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGCAG AGGAATCGGA GAAGGCCGCA ACGGAGCAAG AGCCGCTGGA AGGGACAGAA 
CAGACACTAG ATGCGGAGGA GGAGCAGGAG GAATCCGAAG AAGCGGCCTG TGGCAGCAAG 
AAACGGGTAG TGCCAGGTAT TGTGTACCTG GGCCATATCC CGCCGCGCTT CCGGCCCCTG 
CACGTCCGCA ACCTTCTCAG CGCCTATGGC GAGGTCGGAC GCGTCTTCTT TCAGGCTGAG 
GACCGGTTCG TGAGACGCAA GAAGAAGGCA GCAGCAGCTG CCGGAGGAAA AAAGCGGTCC 
TACACCAAGG ACTACACCGA GGGATGGGTG GAGTTCCGTG ACAAGCGCAT AGCCAAGCGC 
GTGGCGGCCA GTCTACACAA CACGCCTATG GGTGCCCGCA GGCGCAGCCC CTTCCGTTAT 
GATCTTTGGA ACCTCAAGTA CTTGCACCGT TTCACCTGGT CCCACCTCAG CGAGCACCTC 
GCCTTTGAGC GCCAGGTGCG CAGGCAGCGC TTGAGAGCGG AGGTTGCTCA AGCCAAGCGT 
GAGACCGACT TCTATCTTCA AAGTGTGGAA CGGGGACAAC GCTTTCTTGC GGCCGATGGG 
GACCCTGCTC GCCCAGATGG CTCCTGGACA TTTGCCCAGC GTCCTACTGA GCAGGAACTG 
AGGGCCCGTA AAGCAGCACG GCCAGGGGGA CGTGAACGGG CTCGCCTGGC AACTGCCCAG 
GACAAGGCCC GCTCCAACAA AGGGCTCCTG GCCAGGATCT TTGGAGCCCC GCCACCCTCA 
GAGAGCATGG AGGGACCTTC CCTTGTCAGG GACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037507.1
CDS	31..849
Translation	MEAEESEKAATEQEPLEGTEQTLDAEEEQEESEEAACGSKKRVVPGIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEDRFVRRKKKAAAAAGGKKRSYTKDYTEGWVEFRDKRIAKRVAASLHNTPMGARRRSPFRYDLWNLKYLHRFTWSHLSEHLAFERQVRRQRLRAEVAQAKRETDFYLQSVERGQRFLAADGDPARPDGSWTFAQRPTEQELRARKAARPGGRERARLATAQDKARSNKGLLARIFGAPPPSESMEGPSLVRDS

Target ORF information:

RefSeq Version	NM_013375.4
Organism	Homo sapiens(human)
Definition	Homo sapiens activator of basal transcription 1 (ABT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013375.4

ORF Insert Sequence:

ATGGAGGCAG AGGAATCGGA GAAGGCCGCA ACGGAGCAAG AGCCGCTGGA AGGGACAGAA 
CAGACACTAG ATGCGGAGGA GGAGCAGGAG GAATCCGAAG AAGCGGCCTG TGGCAGCAAG 
AAACGGGTAG TGCCAGGTAT TGTGTACCTG GGCCATATCC CGCCGCGCTT CCGGCCCCTG 
CACGTCCGCA ACCTTCTCAG CGCCTATGGC GAGGTCGGAC GCGTCTTCTT TCAGGCTGAG 
GACCGGTTCG TGAGACGCAA GAAGAAGGCA GCAGCAGCTG CCGGAGGAAA AAAGCGGTCC 
TACACCAAGG ACTACACCGA GGGATGGGTG GAGTTCCGTG ACAAGCGCAT AGCCAAGCGC 
GTGGCGGCCA GTCTACACAA CACGCCTATG GGTGCCCGCA GGCGCAGCCC CTTCCGTTAT 
GATCTTTGGA ACCTCAAGTA CTTGCACCGT TTCACCTGGT CCCACCTCAG CGAGCACCTC 
GCCTTTGAGC GCCAGGTGCG CAGGCAGCGC TTGAGAGCGG AGGTTGCTCA AGCCAAGCGT 
GAGACCGACT TCTATCTTCA AAGTGTGGAA CGGGGACAAC GCTTTCTTGC GGCCGATGGG 
GACCCTGCTC GCCCAGATGG CTCCTGGACA TTTGCCCAGC GTCCTACTGA GCAGGAACTG 
AGGGCCCGTA AAGCAGCACG GCCAGGGGGA CGTGAACGGG CTCGCCTGGC AACTGCCCAG 
GACAAGGCCC GCTCCAACAA AGGGCTCCTG GCCAGGATCT TTGGAGCCCC GCCACCCTCA 
GAGAGCATGG AGGGACCTTC CCTTGTCAGG GACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.
Human molecular genetics18(12)2115-26(2009 Jun)
de Planell-Saguer M,Schroeder DG,Rodicio MC,Cox GA,Mourelatos Z

Protein microarray analysis identifies human cellular prion protein interactors.
Neuropathology and applied neurobiology35(1)16-35(2009 Feb)
Satoh J,Obayashi S,Misawa T,Sumiyoshi K,Oosumi K,Tabunoki H

Nucleolar proteome dynamics.
Nature433(7021)77-83(2005 Jan)
Andersen JS,Lam YW,Leung AK,Ong SE,Lyon CE,Lamond AI,Mann M

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ABT1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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