BLNK cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BLNK
Entrez Gene ID	29760
Full Name	B cell linker
Synonyms	AGM4,BASH,BLNK-S,LY57,SLP-65,SLP65,bca
General protein information	Preferred Names B cell linker Names B-cell linker protein B cell adaptor containing SH2 domain B-cell activation B-cell adapter containing a SH2 domain protein B-cell adapter containing a Src homology 2 domain protein Src homology 2 domain-containing leukocyte protein of 65 kDa Src homology [SH2] domain-containing leukocyte protein of 65 kD cytoplasmic adapter protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q24.1
Summary	This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
Disorder MIM:	604515
Disorder Html:	Agammaglobulinemia 4, 613502 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_013314.3	NP_037446.1	B-cell linker protein isoform 1
XM_011539728.2	XP_011538030.1	B-cell linker protein isoform X1
XM_017016159.1	XP_016871648.1	B-cell linker protein isoform X2
NM_001258441.1	NP_001245370.1	B-cell linker protein isoform 4
NM_001258442.1	NP_001245371.1	B-cell linker protein isoform 5
NM_001258440.1	NP_001245369.1	B-cell linker protein isoform 3
NM_013314.4	NP_037446.1	B-cell linker protein isoform 1
NM_001114094.1	NP_001107566.1	B-cell linker protein isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	BLNK	XP_001159266.1
	BLNK	XP_001100700.2
Canis lupus familiaris (dog)	BLNK	XP_005637631.1
Gallus gallus (chicken)	BLNK	NP_990239.1
Bos taurus (cattle)	BLNK	NP_001039519.1
Rattus norvegicus (Norway rat)	Blnk	NP_001020938.1
Xenopus tropicalis (tropical clawed frog)	blnk	NP_001072164.1
Mus musculus (house mouse)	Blnk	NP_032554.2
Danio rerio (zebrafish)	blnk	NP_998003.1
Homo sapiens (human)	BLNK	NP_037446.1

Gene Ontology
Bibliography

Related articles in PubMed

Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells.
Engelke M, Pirkuliyeva S, K?hn J, Wong L, Boyken J, Herrmann N, Becker S, Griesinger C, Wienands J
Science signaling7(339)ra79(2014 Aug)

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Leung KK, Hause RJ Jr, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)

Cutting edge: feed-forward activation of phospholipase C?2 via C2 domain-mediated binding to SLP65.
Engelke M, Oellerich T, Dittmann K, Hsiao HH, Urlaub H, Serve H, Griesinger C, Wienands J
Journal of immunology (Baltimore, Md. : 1950)191(11)5354-8(2013 Dec)

RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes.
Greif PA, Konstandin NP, Metzeler KH, Herold T, Pasalic Z, Ksienzyk B, Dufour A, Schneider F, Schneider S, Kakadia PM, Braess J, Sauerland MC, Berdel WE, B?chner T, Woermann BJ, Hiddemann W, Spiekermann K, Bohlander SK
Haematologica97(12)1909-15(2012 Dec)

SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.
Draber P, Vonkova I, Stepanek O, Hrdinka M, Kucova M, Skopcova T, Otahal P, Angelisova P, Horejsi V, Yeung M, Weiss A, Brdicka T
Molecular and cellular biology31(22)4550-62(2011 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

vesicular signaling scaffolds are required for B cell activation indicates that vesicles may deliver preassembled signaling cargo to sites of BCR activation.
Title: Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells.

early Ca(2+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 C2 domain to phospho-SLP65.
Title: Cutting edge: feed-forward activation of phospholipase C?2 via C2 domain-mediated binding to SLP65.

up-regulation of BLNK is associated with RUNX1 mutations in cytogenetically normal acute myeloid leukemia.
Title: RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes.

Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 are both required for the onset and progression phases of B-cell antigen receptor signal transduction.
Title: The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.

Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.

The following BLNK gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BLNK cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08933	NM_001114094.1 Latest version!	Homo sapiens B cell linker (BLNK), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$251.30 $359.00
OHu09561	NM_001258440.1 Latest version!	Homo sapiens B cell linker (BLNK), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu09575	NM_001258442.1 Latest version!	Homo sapiens B cell linker (BLNK), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu09579	NM_001258441.1 Latest version!	Homo sapiens B cell linker (BLNK), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu67360	XM_011539728.2 Latest version!	Homo sapiens B cell linker (BLNK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu18802	NM_013314.4 Latest version!	Homo sapiens B cell linker (BLNK), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu91360	XM_017016159.1 Latest version!	Homo sapiens B cell linker (BLNK), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu18802	NM_013314.3	Homo sapiens B cell linker (BLNK), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BLNK ( NM_001114094.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001107566.1 Homo sapiens B cell linker (BLNK), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08933
Clone ID Related Accession (Same CDS sequence)	NM_001114094.1
Accession Version	NM_001114094.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA045252.1, BC018906.2, AF068181.1 and AI307343.1. Transcript Variant: This variant (2) lacks an in-frame exon in the mid-coding region compared to variant 1, resulting in a shorter isoform (2, also known as BLNK-s) compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225546.1, AF068181.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGGTC GAAACAGTGG GGCCTGGGAA ACCAAGTCAC CTCCACCAGC TGCACCATCC 
CCGTTGCCAC GGGCCGGGAA AAAACCAACG ACACCACTGA AGACAACTCC AGTTGCCTCT 
CAACAGAATG CTTCAAGTGT TTGTGAAGAA AAACCTATAC CTGCTGAACG CCACCGAGGG 
TCAAGTCACA GACAAGAAGC TGTGCAGTCA CCAGTGTTTC CTCCTGCCCA GAAACAAATC 
CACCAAAAAC CCATACCTCT GCCAAGATTT ACAGAAGGGG GAAACCCAAC TGTGGATGGG 
CCCCTACCCA GCTTTTCATC TAATTCCACT ATTTCAGAAC AGGAAGCTGG CGTTCTCTGC 
AAGCCATGGT ATGCTGGAGC CTGTGATCGA AAGTCTGCTG AAGAGGCATT GCACAGATCA 
AACAAGGATG GATCATTTCT TATTCGGAAA AGCTCTGGCC ATGATTCCAA ACAACCATAT 
ACACTAGTTG TATTCTTTAA TAAGCGAGTA TATAATATTC CTGTGCGATT TATTGAAGCA 
ACAAAACAAT ATGCCTTGGG CAGAAAGAAA AATGGTGAAG AGTACTTTGG AAGTGTTGCT 
GAAATCATCA GGAATCATCA ACATAGTCCT TTGGTTCTTA TTGACAGTCA GAATAACACA 
AAAGATTCCA CCAGACTGAA GTATGCAGTT AAAGTTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001107566.1
CDS	179..1480
Translation	MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	NM_001114094.1
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001114094.1

ORF Insert Sequence:

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGGTC GAAACAGTGG GGCCTGGGAA ACCAAGTCAC CTCCACCAGC TGCACCATCC 
CCGTTGCCAC GGGCCGGGAA AAAACCAACG ACACCACTGA AGACAACTCC AGTTGCCTCT 
CAACAGAATG CTTCAAGTGT TTGTGAAGAA AAACCTATAC CTGCTGAACG CCACCGAGGG 
TCAAGTCACA GACAAGAAGC TGTGCAGTCA CCAGTGTTTC CTCCTGCCCA GAAACAAATC 
CACCAAAAAC CCATACCTCT GCCAAGATTT ACAGAAGGGG GAAACCCAAC TGTGGATGGG 
CCCCTACCCA GCTTTTCATC TAATTCCACT ATTTCAGAAC AGGAAGCTGG CGTTCTCTGC 
AAGCCATGGT ATGCTGGAGC CTGTGATCGA AAGTCTGCTG AAGAGGCATT GCACAGATCA 
AACAAGGATG GATCATTTCT TATTCGGAAA AGCTCTGGCC ATGATTCCAA ACAACCATAT 
ACACTAGTTG TATTCTTTAA TAAGCGAGTA TATAATATTC CTGTGCGATT TATTGAAGCA 
ACAAAACAAT ATGCCTTGGG CAGAAAGAAA AATGGTGAAG AGTACTTTGG AAGTGTTGCT 
GAAATCATCA GGAATCATCA ACATAGTCCT TTGGTTCTTA TTGACAGTCA GAATAACACA 
AAAGATTCCA CCAGACTGAA GTATGCAGTT AAAGTTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLNK ( NM_001258440.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001245369.1 Homo sapiens B cell linker (BLNK), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu09561
Clone ID Related Accession (Same CDS sequence)	NM_001258440.1
Accession Version	NM_001258440.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA045252.1, AM180337.1 and AI307343.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region compared to variant 1, resulting in a shorter isoform (3) compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.687544.1, AM180337.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGTACTT TGGAAGTGTT GCTGAAATCA TCAGGAATCA TCAACATAGT 
CCTTTGGTTC TTATTGACAG TCAGAATAAC ACAAAAGATT CCACCAGACT GAAGTATGCA 
GTTAAAGTTT CATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245369.1
CDS	119..1333
Translation	MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	NM_001258440.1
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258440.1

ORF Insert Sequence:

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGTACTT TGGAAGTGTT GCTGAAATCA TCAGGAATCA TCAACATAGT 
CCTTTGGTTC TTATTGACAG TCAGAATAAC ACAAAAGATT CCACCAGACT GAAGTATGCA 
GTTAAAGTTT CATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLNK ( NM_001258442.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001245371.1 Homo sapiens B cell linker (BLNK), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu09575
Clone ID Related Accession (Same CDS sequence)	NM_001258442.1
Accession Version	NM_001258442.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA045252.1, AM180327.1 and AI307343.1. Transcript Variant: This variant (5) lacks 3 in-frame exons in the mid- and 3' coding regions, and uses alternate in-frame donor and acceptor splice sites compared to variant 1, resulting in a shorter isoform (5) compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM180327.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG AACAGCTTCA 
GGTCGAAACA GTGGGGCCTG GGAAACCAAG TCACCTCCAC CAGCTGCACC ATCCCCGTTG 
CCACGGGCCG GGAAAAAACC AACGACACCA CTGAAGACAA CTCCAGTTGC CTCTCAACAG 
AATGCTTCAA GTGTTTGTGA AGAAAAACCT ATACCTGCTG AACGCCACCG AGGGTCAAGT 
CACAGACAAG AAGCTGTGCA GTCACCAGTG TTTCCTCCTG CCCAGAAACA AATCCACCAA 
AAACCCATAC CTCTGCCAAG ATTTACAGAA GGGGGAAACC CAACTGTGGA TGGGCCCCTA 
CCCAGCTTTT CATCTAATTC CACTATTTCA GAACAGGAAG CTGGCGTTCT CTGCAAGCCA 
TGGTATGCTG GAGCCTGTGA TCGAAAGTCT GCTGAAGAGG CATTGCACAG ATCAAACAAG 
TACTTTGGAA GTGTTGCTGA AATCATCAGG AATCATCAAC ATAGTCCTTT GGTTCTTATT 
GACAGTCAGA ATAACACAAA AGATTCCACC AGACTGAAGT ATGCAGTTAA AGTTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245371.1
CDS	119..1018
Translation	MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	NM_001258442.1
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258442.1

ORF Insert Sequence:

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG AACAGCTTCA 
GGTCGAAACA GTGGGGCCTG GGAAACCAAG TCACCTCCAC CAGCTGCACC ATCCCCGTTG 
CCACGGGCCG GGAAAAAACC AACGACACCA CTGAAGACAA CTCCAGTTGC CTCTCAACAG 
AATGCTTCAA GTGTTTGTGA AGAAAAACCT ATACCTGCTG AACGCCACCG AGGGTCAAGT 
CACAGACAAG AAGCTGTGCA GTCACCAGTG TTTCCTCCTG CCCAGAAACA AATCCACCAA 
AAACCCATAC CTCTGCCAAG ATTTACAGAA GGGGGAAACC CAACTGTGGA TGGGCCCCTA 
CCCAGCTTTT CATCTAATTC CACTATTTCA GAACAGGAAG CTGGCGTTCT CTGCAAGCCA 
TGGTATGCTG GAGCCTGTGA TCGAAAGTCT GCTGAAGAGG CATTGCACAG ATCAAACAAG 
TACTTTGGAA GTGTTGCTGA AATCATCAGG AATCATCAAC ATAGTCCTTT GGTTCTTATT 
GACAGTCAGA ATAACACAAA AGATTCCACC AGACTGAAGT ATGCAGTTAA AGTTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLNK ( NM_001258441.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001245370.1 Homo sapiens B cell linker (BLNK), transcript variant 4, mRNA.

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CloneID	OHu09579
Clone ID Related Accession (Same CDS sequence)	NM_001258441.1
Accession Version	NM_001258441.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA045252.1, AM180332.1 and AI307343.1. Transcript Variant: This variant (4) lacks two in-frame exons in the mid- and 3' coding regions compared to variant 1, resulting in a shorter isoform (4) compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM180332.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGGTC GAAACAGTGG GGCCTGGGAA ACCAAGTCAC CTCCACCAGC TGCACCATCC 
CCGTTGCCAC GGGCCGGGAA AAAACCAACG ACACCACTGA AGACAACTCC AGTTGCCTCT 
CAACAGAATG CTTCAAGTGT TTGTGAAGAA AAACCTATAC CTGCTGAACG CCACCGAGGG 
TCAAGTCACA GACAAGAAGC TGTGCAGTCA CCAGTGTTTC CTCCTGCCCA GAAACAAATC 
CACCAAAAAC CCATACCTCT GCCAAGATTT ACAGAAGGGG GAAACCCAAC TGTGGATGGG 
CCCCTACCCA GCTTTTCATC TAATTCCACT ATTTCAGAAC AGGAAGCTGG CGTTCTCTGC 
AAGCCATGGT ATGCTGGAGC CTGTGATCGA AAGTCTGCTG AAGAGGCATT GCACAGATCA 
AACAAGTACT TTGGAAGTGT TGCTGAAATC ATCAGGAATC ATCAACATAG TCCTTTGGTT 
CTTATTGACA GTCAGAATAA CACAAAAGAT TCCACCAGAC TGAAGTATGC AGTTAAAGTT 
TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245370.1
CDS	119..1264
Translation	MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	NM_001258441.1
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258441.1

ORF Insert Sequence:

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGGTC GAAACAGTGG GGCCTGGGAA ACCAAGTCAC CTCCACCAGC TGCACCATCC 
CCGTTGCCAC GGGCCGGGAA AAAACCAACG ACACCACTGA AGACAACTCC AGTTGCCTCT 
CAACAGAATG CTTCAAGTGT TTGTGAAGAA AAACCTATAC CTGCTGAACG CCACCGAGGG 
TCAAGTCACA GACAAGAAGC TGTGCAGTCA CCAGTGTTTC CTCCTGCCCA GAAACAAATC 
CACCAAAAAC CCATACCTCT GCCAAGATTT ACAGAAGGGG GAAACCCAAC TGTGGATGGG 
CCCCTACCCA GCTTTTCATC TAATTCCACT ATTTCAGAAC AGGAAGCTGG CGTTCTCTGC 
AAGCCATGGT ATGCTGGAGC CTGTGATCGA AAGTCTGCTG AAGAGGCATT GCACAGATCA 
AACAAGTACT TTGGAAGTGT TGCTGAAATC ATCAGGAATC ATCAACATAG TCCTTTGGTT 
CTTATTGACA GTCAGAATAA CACAAAAGAT TCCACCAGAC TGAAGTATGC AGTTAAAGTT 
TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLNK ( NM_013314.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_037446.1 Homo sapiens B cell linker (BLNK), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18802
Clone ID Related Accession (Same CDS sequence)	NM_013314.3 , NM_013314.4
Accession Version	NM_013314.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA045252.1, BC018906.2, AF068180.1 and AI307343.1. This sequence is a reference standard in the RefSeqGene project. On Jan 30, 2008 this sequence version replaced NM_013314.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.508232.1, SRR1163655.50255.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGGATGG ATCATTTCTT ATTCGGAAAA GCTCTGGCCA TGATTCCAAA 
CAACCATATA CACTAGTTGT ATTCTTTAAT AAGCGAGTAT ATAATATTCC TGTGCGATTT 
ATTGAAGCAA CAAAACAATA TGCCTTGGGC AGAAAGAAAA ATGGTGAAGA GTACTTTGGA 
AGTGTTGCTG AAATCATCAG GAATCATCAA CATAGTCCTT TGGTTCTTAT TGACAGTCAG 
AATAACACAA AAGATTCCAC CAGACTGAAG TATGCAGTTA AAGTTTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037446.1
CDS	179..1549
Translation	MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	NM_013314.3
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013314.3

ORF Insert Sequence:

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGGATGG ATCATTTCTT ATTCGGAAAA GCTCTGGCCA TGATTCCAAA 
CAACCATATA CACTAGTTGT ATTCTTTAAT AAGCGAGTAT ATAATATTCC TGTGCGATTT 
ATTGAAGCAA CAAAACAATA TGCCTTGGGC AGAAAGAAAA ATGGTGAAGA GTACTTTGGA 
AGTGTTGCTG AAATCATCAG GAATCATCAA CATAGTCCTT TGGTTCTTAT TGACAGTCAG 
AATAACACAA AAGATTCCAC CAGACTGAAG TATGCAGTTA AAGTTTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLNK ( XM_011539728.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011538030.1 Homo sapiens B cell linker (BLNK), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu67360
Clone ID Related Accession (Same CDS sequence)	XM_011539728.2
Accession Version	XM_011539728.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-12
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011539728.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END##

ATGGATTCCT CTCCTTGTGC TCTCTTGGCC AGACGAACTT CCCTGGGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGGATGG ATCATTTCTT ATTCGGAAAA GCTCTGGCCA TGATTCCAAA 
CAACCATATA CACTAGTTGT ATTCTTTAAT AAGCGAGTAT ATAATATTCC TGTGCGATTT 
ATTGAAGCAA CAAAACAATA TGCCTTGGGC AGAAAGAAAA ATGGTGAAGA GTACTTTGGA 
AGTGTTGCTG AAATCATCAG GAATCATCAA CATAGTCCTT TGGTTCTTAT TGACAGTCAG 
AATAACACAA AAGATTCCAC CAGACTGAAG TATGCAGTTA AAGTTTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011538030.1
CDS	56..1426
Translation	MDSSPCALLARRTSLGQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	XM_011539728.2
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011539728.2

ORF Insert Sequence:

ATGGATTCCT CTCCTTGTGC TCTCTTGGCC AGACGAACTT CCCTGGGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGGATGG ATCATTTCTT ATTCGGAAAA GCTCTGGCCA TGATTCCAAA 
CAACCATATA CACTAGTTGT ATTCTTTAAT AAGCGAGTAT ATAATATTCC TGTGCGATTT 
ATTGAAGCAA CAAAACAATA TGCCTTGGGC AGAAAGAAAA ATGGTGAAGA GTACTTTGGA 
AGTGTTGCTG AAATCATCAG GAATCATCAA CATAGTCCTT TGGTTCTTAT TGACAGTCAG 
AATAACACAA AAGATTCCAC CAGACTGAAG TATGCAGTTA AAGTTTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLNK ( NM_013314.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_037446.1 Homo sapiens B cell linker (BLNK), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18802
Clone ID Related Accession (Same CDS sequence)	NM_013314.3 , NM_013314.4
Accession Version	NM_013314.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA045252.1, BC018906.2, AF068180.1, AI307343.1 and AC021037.6. On Dec 4, 2019 this sequence version replaced NM_013314.3. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC018906.2, AF068180.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGGATGG ATCATTTCTT ATTCGGAAAA GCTCTGGCCA TGATTCCAAA 
CAACCATATA CACTAGTTGT ATTCTTTAAT AAGCGAGTAT ATAATATTCC TGTGCGATTT 
ATTGAAGCAA CAAAACAATA TGCCTTGGGC AGAAAGAAAA ATGGTGAAGA GTACTTTGGA 
AGTGTTGCTG AAATCATCAG GAATCATCAA CATAGTCCTT TGGTTCTTAT TGACAGTCAG 
AATAACACAA AAGATTCCAC CAGACTGAAG TATGCAGTTA AAGTTTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037446.1
CDS	172..1542
Translation	MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	NM_013314.4
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013314.4

ORF Insert Sequence:

ATGGACAAGC TTAATAAAAT AACCGTCCCC GCCAGTCAGA AGTTGAGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGCTC CCATGGTGAA TAGATCAACC AAGCCAAATT CCTCAACGCC CGCCTCTCCT 
CCAGGAACAG CTTCAGGTCG AAACAGTGGG GCCTGGGAAA CCAAGTCACC TCCACCAGCT 
GCACCATCCC CGTTGCCACG GGCCGGGAAA AAACCAACGA CACCACTGAA GACAACTCCA 
GTTGCCTCTC AACAGAATGC TTCAAGTGTT TGTGAAGAAA AACCTATACC TGCTGAACGC 
CACCGAGGGT CAAGTCACAG ACAAGAAGCT GTGCAGTCAC CAGTGTTTCC TCCTGCCCAG 
AAACAAATCC ACCAAAAACC CATACCTCTG CCAAGATTTA CAGAAGGGGG AAACCCAACT 
GTGGATGGGC CCCTACCCAG CTTTTCATCT AATTCCACTA TTTCAGAACA GGAAGCTGGC 
GTTCTCTGCA AGCCATGGTA TGCTGGAGCC TGTGATCGAA AGTCTGCTGA AGAGGCATTG 
CACAGATCAA ACAAGGATGG ATCATTTCTT ATTCGGAAAA GCTCTGGCCA TGATTCCAAA 
CAACCATATA CACTAGTTGT ATTCTTTAAT AAGCGAGTAT ATAATATTCC TGTGCGATTT 
ATTGAAGCAA CAAAACAATA TGCCTTGGGC AGAAAGAAAA ATGGTGAAGA GTACTTTGGA 
AGTGTTGCTG AAATCATCAG GAATCATCAA CATAGTCCTT TGGTTCTTAT TGACAGTCAG 
AATAACACAA AAGATTCCAC CAGACTGAAG TATGCAGTTA AAGTTTCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLNK ( XM_017016159.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016871648.1 Homo sapiens B cell linker (BLNK), transcript variant X2, mRNA.

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CloneID	OHu91360
Clone ID Related Accession (Same CDS sequence)	XM_017016159.1
Accession Version	XM_017016159.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-12
Organism	Homo sapiens(human)
Product	B-cell linker protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END##

ATGGATTCCT CTCCTTGTGC TCTCTTGGCC AGACGAACTT CCCTGGGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGGTC GAAACAGTGG GGCCTGGGAA ACCAAGTCAC CTCCACCAGC TGCACCATCC 
CCGTTGCCAC GGGCCGGGAA AAAACCAACG ACACCACTGA AGACAACTCC AGTTGCCTCT 
CAACAGAATG CTTCAAGTGT TTGTGAAGAA AAACCTATAC CTGCTGAACG CCACCGAGGG 
TCAAGTCACA GACAAGAAGC TGTGCAGTCA CCAGTGTTTC CTCCTGCCCA GAAACAAATC 
CACCAAAAAC CCATACCTCT GCCAAGATTT ACAGAAGGGG GAAACCCAAC TGTGGATGGG 
CCCCTACCCA GCTTTTCATC TAATTCCACT ATTTCAGAAC AGGAAGCTGG CGTTCTCTGC 
AAGCCATGGT ATGCTGGAGC CTGTGATCGA AAGTCTGCTG AAGAGGCATT GCACAGATCA 
AACAAGGATG GATCATTTCT TATTCGGAAA AGCTCTGGCC ATGATTCCAA ACAACCATAT 
ACACTAGTTG TATTCTTTAA TAAGCGAGTA TATAATATTC CTGTGCGATT TATTGAAGCA 
ACAAAACAAT ATGCCTTGGG CAGAAAGAAA AATGGTGAAG AGTACTTTGG AAGTGTTGCT 
GAAATCATCA GGAATCATCA ACATAGTCCT TTGGTTCTTA TTGACAGTCA GAATAACACA 
AAAGATTCCA CCAGACTGAA GTATGCAGTT AAAGTTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016871648.1
CDS	57..1358
Translation	MDSSPCALLARRTSLGQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS

Target ORF information:

RefSeq Version	XM_017016159.1
Organism	Homo sapiens(human)
Definition	Homo sapiens B cell linker (BLNK), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016159.1

ORF Insert Sequence:

ATGGATTCCT CTCCTTGTGC TCTCTTGGCC AGACGAACTT CCCTGGGGCA GCTTCAAAAG 
ATGGTCCATG ATATTAAAAA CAATGAAGGT GGAATAATGA ATAAAATCAA AAAGCTAAAA 
GTCAAAGCAC CTCCAAGTGT TCCTCGAAGG GACTACGCTT CAGAGAGCCC TGCTGACGAA 
GAGGAGCAGT GGTCCGATGA CTTTGACAGC GACTATGAAA ATCCAGATGA GCACTCGGAC 
TCAGAGATGT ACGTGATGCC CGCCGAGGAG AACGCTGATG ACAGCTACGA GCCGCCTCCA 
GTAGAGCAGG AAACCAGGCC GGTTCACCCA GCCCTGCCCT TCGCCAGAGG CGAGTATATA 
GACAATCGAT CAAGCCAGAG GCATTCCCCA CCCTTCAGCA AGACACTTCC CAGTAAGCCC 
AGCTGGCCTT CAGAGAAAGC AAGGCTCACC TCCACCCTGC CGGCCCTGAC TGCTTTGCAG 
AAACCTCAAG TCCCACCCAA ACCCAAAGGC CTCCTTGAGG ATGAGGCTGA TTATGTGGTC 
CCCGTGGAAG ATAATGATGA AAACTATATT CATCCCACAG AAAGCAGTTC ACCTCCACCT 
GAAAAAGGTC GAAACAGTGG GGCCTGGGAA ACCAAGTCAC CTCCACCAGC TGCACCATCC 
CCGTTGCCAC GGGCCGGGAA AAAACCAACG ACACCACTGA AGACAACTCC AGTTGCCTCT 
CAACAGAATG CTTCAAGTGT TTGTGAAGAA AAACCTATAC CTGCTGAACG CCACCGAGGG 
TCAAGTCACA GACAAGAAGC TGTGCAGTCA CCAGTGTTTC CTCCTGCCCA GAAACAAATC 
CACCAAAAAC CCATACCTCT GCCAAGATTT ACAGAAGGGG GAAACCCAAC TGTGGATGGG 
CCCCTACCCA GCTTTTCATC TAATTCCACT ATTTCAGAAC AGGAAGCTGG CGTTCTCTGC 
AAGCCATGGT ATGCTGGAGC CTGTGATCGA AAGTCTGCTG AAGAGGCATT GCACAGATCA 
AACAAGGATG GATCATTTCT TATTCGGAAA AGCTCTGGCC ATGATTCCAA ACAACCATAT 
ACACTAGTTG TATTCTTTAA TAAGCGAGTA TATAATATTC CTGTGCGATT TATTGAAGCA 
ACAAAACAAT ATGCCTTGGG CAGAAAGAAA AATGGTGAAG AGTACTTTGG AAGTGTTGCT 
GAAATCATCA GGAATCATCA ACATAGTCCT TTGGTTCTTA TTGACAGTCA GAATAACACA 
AAAGATTCCA CCAGACTGAA GTATGCAGTT AAAGTTTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells.
Science signaling7(339)ra79(2014 Aug)
Engelke M,Pirkuliyeva S,K?hn J,Wong L,Boyken J,Herrmann N,Becker S,Griesinger C,Wienands J

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)
Leung KK,Hause RJ Jr,Barkinge JL,Ciaccio MF,Chuu CP,Jones RB

Cutting edge: feed-forward activation of phospholipase C?2 via C2 domain-mediated binding to SLP65.
Journal of immunology (Baltimore, Md. : 1950)191(11)5354-8(2013 Dec)
Engelke M,Oellerich T,Dittmann K,Hsiao HH,Urlaub H,Serve H,Griesinger C,Wienands J

RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes.
Haematologica97(12)1909-15(2012 Dec)
Greif PA,Konstandin NP,Metzeler KH,Herold T,Pasalic Z,Ksienzyk B,Dufour A,Schneider F,Schneider S,Kakadia PM,Braess J,Sauerland MC,Berdel WE,B?chner T,Woermann BJ,Hiddemann W,Spiekermann K,Bohlander SK

SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.
Molecular and cellular biology31(22)4550-62(2011 Nov)
Draber P,Vonkova I,Stepanek O,Hrdinka M,Kucova M,Skopcova T,Otahal P,Angelisova P,Horejsi V,Yeung M,Weiss A,Brdicka T

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BLNK cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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