GTF2H4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GTF2H4
Entrez Gene ID	2968
Full Name	general transcription factor IIH subunit 4
Synonyms	P52,TFB2,TFIIH
General protein information	Preferred Names general transcription factor IIH subunit 4 Names general transcription factor IIH subunit 4 BTF2 p52 TFIIH basal transcription factor complex p52 subunit basic transcription factor 2 52 kDa subunit general transcription factor IIH polypeptide 4 general transcription factor IIH, polypeptide 4, 52kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.33
Disorder MIM:	601760

mRNA and Protein(s)

mRNA	Protein	Name
NM_001517.4	NP_001508.1	general transcription factor IIH subunit 4
NM_001517.5	NP_001508.1	general transcription factor IIH subunit 4

Pathways from BioSystems

Homologies

	GTF2H4	NP_001040607.1
Danio rerio (zebrafish)	gtf2h4	NP_956221.1
Neurospora crassa	NCU05523	XP_960485.2
Arabidopsis thaliana (thale cress)	AT4G17020	NP_974564.1
Canis lupus familiaris (dog)	GTF2H4	XP_005627183.1
Drosophila melanogaster (fruit fly)	mrn	NP_648780.1
Schizosaccharomyces pombe (fission yeast)	tfb2	NP_596563.1
Kluyveromyces lactis	KLLA0F01056g	XP_455127.1
Eremothecium gossypii	AGOS_ADL274W	NP_983822.1
Xenopus tropicalis (tropical clawed frog)	gtf2h4	NP_001015845.1
Bos taurus (cattle)	GTF2H4	NP_001094527.1
Mus musculus (house mouse)	Gtf2h4	NP_034494.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010984	XP_309710.1
Saccharomyces cerevisiae (baker's yeast)	TFB2	NP_015203.1
Magnaporthe oryzae (rice blast fungus)	MGG_00397	XP_003718679.1
Homo sapiens (human)	GTF2H4	NP_001508.1
Pan troglodytes (chimpanzee)	GTF2H4	NP_001038968.1
Rattus norvegicus (Norway rat)	Gtf2h4	NP_997666.1
Oryza sativa (rice)	Os04g0680000	NP_001054284.1
Xenopus tropicalis (tropical clawed frog)	LOC101731871	XP_004911969.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium.
Wang M, Liu H, Liu Z, Yi X, Bickeboller H, Hung RJ, Brennan P, Landi MT, Caporaso N, Christiani DC, Doherty JA, , Amos CI, Wei Q
Carcinogenesis37(9)888-896(2016 Sep)

Near-atomic resolution visualization of human transcription promoter opening.
He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E
Nature533(7603)359-65(2016 05)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

functional genetic variants of GTF2H4 confer susceptibility to lung cancer.
Title: Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium.

GTF2H4 variants may not be associated with susceptibility to aspirin-exacerbated respiratory disease and obstructive symptoms in asthmatics.
Title: Lack of association between GTF2H4 genetic variants and AERD development and FEV1 decline by aspirin provocation.

Observational study of gene-disease association. (HuGE Navigator)
Title: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.

A single nucleotide polymorphism variant within the general transcription factor IIH, polypeptide 4 gene, GTF2H4, on chromosome 6p21.33 was significantly associated with MS
Title: Variation within DNA repair pathway genes and risk of multiple sclerosis.

Study demonstrates that an essential initiation factor, TFB2, forms a network of interactions with DNA near the transcription start site and facilitates promoter melting but may not be essential for promoter recognition.
Title: TFB2 is a transient component of the catalytic site of the human mitochondrial RNA polymerase.

The following GTF2H4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GTF2H4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29656	NM_001517.5 Latest version!	Homo sapiens general transcription factor IIH subunit 4 (GTF2H4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu29656	NM_001517.4	Homo sapiens general transcription factor IIH subunit 4 (GTF2H4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GTF2H4 ( NM_001517.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001508.1 Homo sapiens general transcription factor IIH subunit 4 (GTF2H4), mRNA.

Price & Availability↑

CloneID	OHu29656
Clone ID Related Accession (Same CDS sequence)	NM_001517.4 , NM_001517.5
Accession Version	NM_001517.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	general transcription factor IIH subunit 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI460355.1 and BC004935.1. On or before Oct 18, 2004 this sequence version replaced XM_378195.2, NM_001517.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004935.1, SRR1163657.449600.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAGCA CCCCTTCAAG GGGACTGAAC CGAGTACACC TACAATGCAG GAATCTGCAG 
GAATTCTTAG GGGGCCTGAG CCCTGGGGTA TTGGACCGAT TGTATGGGCA CCCTGCCACA 
TGTCTGGCTG TCTTCAGGGA GCTCCCATCC TTGGCTAAGA ACTGGGTGAT GCGGATGCTC 
TTTCTGGAGC AGCCTTTGCC ACAGGCTGCT GTAGCTCTGT GGGTAAAGAA GGAATTCAGC 
AAGGCTCAGG AGGAAAGTAC AGGGCTGCTG AGCGGCCTCC GGATCTGGCA CACACAGCTG 
CTCCCAGGCG GGCTCCAGGG CCTCATCCTC AACCCCATTT TCCGCCAGAA CCTCCGCATT 
GCCCTTCTGG GTGGGGGGAA GGCCTGGTCT GATGACACAA GTCAGCTGGG ACCAGACAAG 
CATGCCCGGG ACGTTCCCTC CCTTGACAAG TACGCCGAGG AGCGATGGGA GGTGGTCTTG 
CACTTCATGG TGGGCTCCCC CAGTGCAGCT GTCAGCCAGG ACTTGGCTCA GCTCCTCAGC 
CAGGCTGGGC TCATGAAGAG TACTGAACCT GGAGAGCCGC CCTGCATTAC TTCCGCTGGC 
TTCCAGTTCC TGTTGCTGGA CACCCCGGCT CAGCTCTGGT ACTTTATGTT GCAGTATTTG 
CAGACAGCCC AGAGCCGGGG CATGGACCTG GTAGAGATTC TCTCCTTCCT CTTCCAGCTC 
AGCTTCTCTA CTCTGGGCAA GGATTACTCT GTGGAAGGTA TGAGTGATTC TCTGTTGAAC 
TTCCTGCAAC ATCTGCGTGA GTTTGGGCTT GTTTTCCAGA GGAAGAGGAA ATCTCGGCGT 
TACTACCCCA CACGCCTGGC CATCAATCTC TCATCAGGTG TCTCTGGAGC TGGGGGCACT 
GTGCATCAGC CAGGTTTCAT TGTCGTGGAA ACCAATTACC GACTGTATGC CTACACGGAG 
TCGGAGCTGC AGATTGCCCT CATTGCCCTC TTCTCTGAGA TGCTCTATCG GTTCCCCAAC 
ATGGTGGTGG CGCAGGTGAC CCGGGAGAGT GTGCAGCAGG CAATCGCCAG TGGCATCACA 
GCCCAGCAGA TAATCCATTT CCTAAGGACA AGAGCCCACC CAGTGATGCT CAAACAGACA 
CCTGTGCTGC CCCCCACCAT CACCGACCAG ATCCGGCTCT GGGAGCTGGA AAGGGACAGA 
CTCCGGTTCA CTGAGGGTGT CCTGTATAAC CAGTTCCTGT CGCAAGTGGA CTTTGAGCTG 
CTGCTGGCCC ACGCGCGGGA GCTGGGCGTG CTCGTGTTCG AGAACTCGGC CAAGCGGCTC 
ATGGTGGTGA CCCCGGCCGG GCACAGCGAC GTCAAGCGCT TTTGGAAGCG GCAGAAACAT 
AGCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001508.1
CDS	208..1596
Translation	MESTPSRGLNRVHLQCRNLQEFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRMLFLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRIALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLSQAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQLSFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGTVHQPGFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGITAQQIIHFLRTRAHPVMLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS

Target ORF information:

RefSeq Version	NM_001517.4
Organism	Homo sapiens(human)
Definition	Homo sapiens general transcription factor IIH subunit 4 (GTF2H4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001517.4

ORF Insert Sequence:

ATGGAGAGCA CCCCTTCAAG GGGACTGAAC CGAGTACACC TACAATGCAG GAATCTGCAG 
GAATTCTTAG GGGGCCTGAG CCCTGGGGTA TTGGACCGAT TGTATGGGCA CCCTGCCACA 
TGTCTGGCTG TCTTCAGGGA GCTCCCATCC TTGGCTAAGA ACTGGGTGAT GCGGATGCTC 
TTTCTGGAGC AGCCTTTGCC ACAGGCTGCT GTAGCTCTGT GGGTAAAGAA GGAATTCAGC 
AAGGCTCAGG AGGAAAGTAC AGGGCTGCTG AGCGGCCTCC GGATCTGGCA CACACAGCTG 
CTCCCAGGCG GGCTCCAGGG CCTCATCCTC AACCCCATTT TCCGCCAGAA CCTCCGCATT 
GCCCTTCTGG GTGGGGGGAA GGCCTGGTCT GATGACACAA GTCAGCTGGG ACCAGACAAG 
CATGCCCGGG ACGTTCCCTC CCTTGACAAG TACGCCGAGG AGCGATGGGA GGTGGTCTTG 
CACTTCATGG TGGGCTCCCC CAGTGCAGCT GTCAGCCAGG ACTTGGCTCA GCTCCTCAGC 
CAGGCTGGGC TCATGAAGAG TACTGAACCT GGAGAGCCGC CCTGCATTAC TTCCGCTGGC 
TTCCAGTTCC TGTTGCTGGA CACCCCGGCT CAGCTCTGGT ACTTTATGTT GCAGTATTTG 
CAGACAGCCC AGAGCCGGGG CATGGACCTG GTAGAGATTC TCTCCTTCCT CTTCCAGCTC 
AGCTTCTCTA CTCTGGGCAA GGATTACTCT GTGGAAGGTA TGAGTGATTC TCTGTTGAAC 
TTCCTGCAAC ATCTGCGTGA GTTTGGGCTT GTTTTCCAGA GGAAGAGGAA ATCTCGGCGT 
TACTACCCCA CACGCCTGGC CATCAATCTC TCATCAGGTG TCTCTGGAGC TGGGGGCACT 
GTGCATCAGC CAGGTTTCAT TGTCGTGGAA ACCAATTACC GACTGTATGC CTACACGGAG 
TCGGAGCTGC AGATTGCCCT CATTGCCCTC TTCTCTGAGA TGCTCTATCG GTTCCCCAAC 
ATGGTGGTGG CGCAGGTGAC CCGGGAGAGT GTGCAGCAGG CAATCGCCAG TGGCATCACA 
GCCCAGCAGA TAATCCATTT CCTAAGGACA AGAGCCCACC CAGTGATGCT CAAACAGACA 
CCTGTGCTGC CCCCCACCAT CACCGACCAG ATCCGGCTCT GGGAGCTGGA AAGGGACAGA 
CTCCGGTTCA CTGAGGGTGT CCTGTATAAC CAGTTCCTGT CGCAAGTGGA CTTTGAGCTG 
CTGCTGGCCC ACGCGCGGGA GCTGGGCGTG CTCGTGTTCG AGAACTCGGC CAAGCGGCTC 
ATGGTGGTGA CCCCGGCCGG GCACAGCGAC GTCAAGCGCT TTTGGAAGCG GCAGAAACAT 
AGCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GTF2H4 ( NM_001517.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001508.1 Homo sapiens general transcription factor IIH subunit 4 (GTF2H4), mRNA.

Price & Availability↑

CloneID	OHu29656
Clone ID Related Accession (Same CDS sequence)	NM_001517.4 , NM_001517.5
Accession Version	NM_001517.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	general transcription factor IIH subunit 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI460355.1, BC004935.1 and AL669830.9. On Nov 23, 2018 this sequence version replaced NM_001517.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.84695.1, BC004935.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000259895.9/ ENSP00000259895.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAGCA CCCCTTCAAG GGGACTGAAC CGAGTACACC TACAATGCAG GAATCTGCAG 
GAATTCTTAG GGGGCCTGAG CCCTGGGGTA TTGGACCGAT TGTATGGGCA CCCTGCCACA 
TGTCTGGCTG TCTTCAGGGA GCTCCCATCC TTGGCTAAGA ACTGGGTGAT GCGGATGCTC 
TTTCTGGAGC AGCCTTTGCC ACAGGCTGCT GTAGCTCTGT GGGTAAAGAA GGAATTCAGC 
AAGGCTCAGG AGGAAAGTAC AGGGCTGCTG AGCGGCCTCC GGATCTGGCA CACACAGCTG 
CTCCCAGGCG GGCTCCAGGG CCTCATCCTC AACCCCATTT TCCGCCAGAA CCTCCGCATT 
GCCCTTCTGG GTGGGGGGAA GGCCTGGTCT GATGACACAA GTCAGCTGGG ACCAGACAAG 
CATGCCCGGG ACGTTCCCTC CCTTGACAAG TACGCCGAGG AGCGATGGGA GGTGGTCTTG 
CACTTCATGG TGGGCTCCCC CAGTGCAGCT GTCAGCCAGG ACTTGGCTCA GCTCCTCAGC 
CAGGCTGGGC TCATGAAGAG TACTGAACCT GGAGAGCCGC CCTGCATTAC TTCCGCTGGC 
TTCCAGTTCC TGTTGCTGGA CACCCCGGCT CAGCTCTGGT ACTTTATGTT GCAGTATTTG 
CAGACAGCCC AGAGCCGGGG CATGGACCTG GTAGAGATTC TCTCCTTCCT CTTCCAGCTC 
AGCTTCTCTA CTCTGGGCAA GGATTACTCT GTGGAAGGTA TGAGTGATTC TCTGTTGAAC 
TTCCTGCAAC ATCTGCGTGA GTTTGGGCTT GTTTTCCAGA GGAAGAGGAA ATCTCGGCGT 
TACTACCCCA CACGCCTGGC CATCAATCTC TCATCAGGTG TCTCTGGAGC TGGGGGCACT 
GTGCATCAGC CAGGTTTCAT TGTCGTGGAA ACCAATTACC GACTGTATGC CTACACGGAG 
TCGGAGCTGC AGATTGCCCT CATTGCCCTC TTCTCTGAGA TGCTCTATCG GTTCCCCAAC 
ATGGTGGTGG CGCAGGTGAC CCGGGAGAGT GTGCAGCAGG CAATCGCCAG TGGCATCACA 
GCCCAGCAGA TAATCCATTT CCTAAGGACA AGAGCCCACC CAGTGATGCT CAAACAGACA 
CCTGTGCTGC CCCCCACCAT CACCGACCAG ATCCGGCTCT GGGAGCTGGA AAGGGACAGA 
CTCCGGTTCA CTGAGGGTGT CCTGTATAAC CAGTTCCTGT CGCAAGTGGA CTTTGAGCTG 
CTGCTGGCCC ACGCGCGGGA GCTGGGCGTG CTCGTGTTCG AGAACTCGGC CAAGCGGCTC 
ATGGTGGTGA CCCCGGCCGG GCACAGCGAC GTCAAGCGCT TTTGGAAGCG GCAGAAACAT 
AGCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001508.1
CDS	201..1589
Translation	MESTPSRGLNRVHLQCRNLQEFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRMLFLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRIALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLSQAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQLSFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGTVHQPGFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGITAQQIIHFLRTRAHPVMLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS

Target ORF information:

RefSeq Version	NM_001517.5
Organism	Homo sapiens(human)
Definition	Homo sapiens general transcription factor IIH subunit 4 (GTF2H4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001517.5

ORF Insert Sequence:

ATGGAGAGCA CCCCTTCAAG GGGACTGAAC CGAGTACACC TACAATGCAG GAATCTGCAG 
GAATTCTTAG GGGGCCTGAG CCCTGGGGTA TTGGACCGAT TGTATGGGCA CCCTGCCACA 
TGTCTGGCTG TCTTCAGGGA GCTCCCATCC TTGGCTAAGA ACTGGGTGAT GCGGATGCTC 
TTTCTGGAGC AGCCTTTGCC ACAGGCTGCT GTAGCTCTGT GGGTAAAGAA GGAATTCAGC 
AAGGCTCAGG AGGAAAGTAC AGGGCTGCTG AGCGGCCTCC GGATCTGGCA CACACAGCTG 
CTCCCAGGCG GGCTCCAGGG CCTCATCCTC AACCCCATTT TCCGCCAGAA CCTCCGCATT 
GCCCTTCTGG GTGGGGGGAA GGCCTGGTCT GATGACACAA GTCAGCTGGG ACCAGACAAG 
CATGCCCGGG ACGTTCCCTC CCTTGACAAG TACGCCGAGG AGCGATGGGA GGTGGTCTTG 
CACTTCATGG TGGGCTCCCC CAGTGCAGCT GTCAGCCAGG ACTTGGCTCA GCTCCTCAGC 
CAGGCTGGGC TCATGAAGAG TACTGAACCT GGAGAGCCGC CCTGCATTAC TTCCGCTGGC 
TTCCAGTTCC TGTTGCTGGA CACCCCGGCT CAGCTCTGGT ACTTTATGTT GCAGTATTTG 
CAGACAGCCC AGAGCCGGGG CATGGACCTG GTAGAGATTC TCTCCTTCCT CTTCCAGCTC 
AGCTTCTCTA CTCTGGGCAA GGATTACTCT GTGGAAGGTA TGAGTGATTC TCTGTTGAAC 
TTCCTGCAAC ATCTGCGTGA GTTTGGGCTT GTTTTCCAGA GGAAGAGGAA ATCTCGGCGT 
TACTACCCCA CACGCCTGGC CATCAATCTC TCATCAGGTG TCTCTGGAGC TGGGGGCACT 
GTGCATCAGC CAGGTTTCAT TGTCGTGGAA ACCAATTACC GACTGTATGC CTACACGGAG 
TCGGAGCTGC AGATTGCCCT CATTGCCCTC TTCTCTGAGA TGCTCTATCG GTTCCCCAAC 
ATGGTGGTGG CGCAGGTGAC CCGGGAGAGT GTGCAGCAGG CAATCGCCAG TGGCATCACA 
GCCCAGCAGA TAATCCATTT CCTAAGGACA AGAGCCCACC CAGTGATGCT CAAACAGACA 
CCTGTGCTGC CCCCCACCAT CACCGACCAG ATCCGGCTCT GGGAGCTGGA AAGGGACAGA 
CTCCGGTTCA CTGAGGGTGT CCTGTATAAC CAGTTCCTGT CGCAAGTGGA CTTTGAGCTG 
CTGCTGGCCC ACGCGCGGGA GCTGGGCGTG CTCGTGTTCG AGAACTCGGC CAAGCGGCTC 
ATGGTGGTGA CCCCGGCCGG GCACAGCGAC GTCAAGCGCT TTTGGAAGCG GCAGAAACAT 
AGCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium.
Carcinogenesis37(9)888-896(2016 Sep)
Wang M,Liu H,Liu Z,Yi X,Bickeboller H,Hung RJ,Brennan P,Landi MT,Caporaso N,Christiani DC,Doherty JA,,Amos CI,Wei Q

Near-atomic resolution visualization of human transcription promoter opening.
Nature533(7603)359-65(2016 05)
He Y,Yan C,Fang J,Inouye C,Tjian R,Ivanov I,Nogales E

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

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GTF2H4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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