GSTA2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GSTA2
Entrez Gene ID	2939
Full Name	glutathione S-transferase alpha 2
Synonyms	GST2,GSTA2-2,GTA2,GTH2
General protein information	Preferred Names glutathione S-transferase alpha 2 Names glutathione S-transferase A2 GST HA subunit 2 GST class-alpha member 2 GST-gamma S-(hydroxyalkyl)glutathione lyase A2 glutathione S-alkyltransferase A2 glutathione S-aralkyltransferase A2 glutathione S-aryltransferase A2 liver GST2 testis tissue sperm-binding protein Li 59n
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p12.2
Summary	Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008].
Disorder MIM:	138360

mRNA and Protein(s)

mRNA	Protein	Name
XM_011514532.3	XP_011512834.1	glutathione S-transferase A2 isoform X1
XM_011514532.2	XP_011512834.1	glutathione S-transferase A2 isoform X1
XM_011514532.1	XP_011512834.1	glutathione S-transferase A2 isoform X1
NM_000846.4	NP_000837.3	glutathione S-transferase A2
NM_000846.5	NP_000837.3	glutathione S-transferase A2

Pathways from BioSystems

Homologies

Homo sapiens (human)	GSTA2	NP_000837.3
Rattus norvegicus (Norway rat)	LOC501110	NP_001019532.1
Gallus gallus (chicken)	GSTA	NP_001001776.1
Gallus gallus (chicken)	LOC396380	NP_990743.1
Pan troglodytes (chimpanzee)	GSTA2	XP_001153130.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation.
Bonifazi F, Storci G, Bandini G, Marasco E, Dan E, Zani E, Albani F, Bertoni S, Bontadini A, De Carolis S, Sapienza MR, Rizzi S, Motta MR, Ferioli M, Garagnani P, Cavo M, Mantovani V, Bonaf? M
Haematologica99(1)172-9(2014 Jan)

Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.
Matsumura T, Imamichi Y, Mizutani T, Ju Y, Yazawa T, Kawabe S, Kanno M, Ayabe T, Katsumata N, Fukami M, Inatani M, Akagi Y, Umezawa A, Ogata T, Miyamoto K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology27(8)3198-208(2013 Aug)

Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.
Maekawa K, Hamaguchi T, Saito Y, Tatewaki N, Kurose K, Kaniwa N, Eguchi Nakajima T, Kato K, Yamada Y, Shimada Y, Yoshida T, Kamatani N, Ura T, Saito M, Muro K, Fuse N, Yoshino T, Doi T, Otsu A, Saijo N, Sawada J, Okuda H, Matsumura Y
Drug metabolism and pharmacokinetics26(6)646-58(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the GSTA2 S112T polymorphism is predictive of transplant outcome in patients receiving busulfan in the preparative regimen, at least in association with cyclophosphamide.
Title: Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation.

Data indicate that steroidogenic factor 1 (SF-1) and glutathione S-transferase A (GSTA) family genes (hGSTA1-hGSTA4) are involved in steroidogenesis.
Title: Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.

Single nucleotide polymorphism in GSTA2 is associated with low-stage non-small cell lung cancer.
Title: Systematic evaluation of genetic variants in three biological pathways on patient survival in low-stage non-small cell lung cancer.

By direct resequencing of the 5'-flanking region, all the exons, and their flanking introns for 107 patients, 29 and 27 variants were identified in GSTA1 and GSTA2, respectively.
Title: Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.

Even with typical substrates, the astonishing concentration of glutathione transferase present in hepatocytes, causes an unusual "inverted" kinetics whereby the classical trends of v versus E and v versus S are reversed
Title: The extended catalysis of glutathione transferase.

The following GSTA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GSTA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19063	NM_000846.5 Latest version!	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu19063	XM_011514532.3 Latest version!	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu19063	XM_011514532.2	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu19063	XM_011514532.1	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu19063	NM_000846.4	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GSTA2 ( NM_000846.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000837.3 Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.

Price & Availability↑

CloneID	OHu19063
Clone ID Related Accession (Same CDS sequence)	XM_011514532.3 , XM_011514532.2 , XM_011514532.1 , NM_000846.4 , NM_000846.5
Accession Version	NM_000846.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	glutathione S-transferase A2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from H62933.1, BC002895.2, AL109918.25, AK292602.1 and BU685446.1. This sequence is a reference standard in the RefSeqGene project. On Nov 29, 2008 this sequence version replaced NM_000846.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM005682.1, AK292602.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000837.3
CDS	151..819
Translation	MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF

Target ORF information:

RefSeq Version	NM_000846.4
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000846.4

ORF Insert Sequence:

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSTA2 ( NM_000846.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000837.3 Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.

Price & Availability↑

CloneID	OHu19063
Clone ID Related Accession (Same CDS sequence)	XM_011514532.3 , XM_011514532.2 , XM_011514532.1 , NM_000846.4 , NM_000846.5
Accession Version	NM_000846.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	glutathione S-transferase A2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC002895.2, AL109918.25, AK292602.1 and BU685446.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000846.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM005682.1, SRR5189664.131477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000493422.3/ ENSP00000420168.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000837.3
CDS	63..731
Translation	MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF

Target ORF information:

RefSeq Version	NM_000846.5
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000846.5

ORF Insert Sequence:

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSTA2 ( XM_011514532.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512834.1 Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu19063
Clone ID Related Accession (Same CDS sequence)	XM_011514532.3 , XM_011514532.2 , XM_011514532.1 , NM_000846.4 , NM_000846.5
Accession Version	XM_011514532.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	glutathione S-transferase A2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011514532.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512834.1
CDS	144..812
Translation	MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF

Target ORF information:

RefSeq Version	XM_011514532.3
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514532.3

ORF Insert Sequence:

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSTA2 ( XM_011514532.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512834.1 Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu19063
Clone ID Related Accession (Same CDS sequence)	XM_011514532.3 , XM_011514532.2 , XM_011514532.1 , NM_000846.4 , NM_000846.5
Accession Version	XM_011514532.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	glutathione S-transferase A2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514532.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512834.1
CDS	143..811
Translation	MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF

Target ORF information:

RefSeq Version	XM_011514532.2
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514532.2

ORF Insert Sequence:

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSTA2 ( XM_011514532.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512834.1 Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.

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CloneID	OHu19063
Clone ID Related Accession (Same CDS sequence)	XM_011514532.3 , XM_011514532.2 , XM_011514532.1 , NM_000846.4 , NM_000846.5
Accession Version	XM_011514532.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	glutathione S-transferase A2 isoform X1
Comment

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512834.1
Translation	MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF

Target ORF information:

RefSeq Version	XM_011514532.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens glutathione S-transferase alpha 2 (GSTA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514532.1

ORF Insert Sequence:

ATGGCAGAGA AGCCCAAGCT CCACTACTCC AATATACGGG GCAGAATGGA GTCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAGAAAT TTATAAAATC TGCAGAAGAT 
TTGGACAAGT TAAGAAATGA TGGATATTTG ATGTTCCAGC AAGTGCCAAT GGTTGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAG CAAATACAAC 
CTCTATGGGA AAGACATAAA GGAGAAAGCC CTGATTGATA TGTATATAGA AGGTATAGCA 
GATTTGGGTG AAATGATCCT TCTTCTGCCC TTTAGTCAAC CTGAGGAACA AGATGCCAAG 
CTTGCCTTGA TCCAAGAGAA AACAAAAAAT CGCTACTTCC CTGCCTTTGA AAAAGTCTTA 
AAGAGCCACG GACAAGACTA CCTTGTTGGC AACAAGCTGA GCCGGGCTGA CATTCACCTG 
GTGGAACTTC TCTACTACGT GGAAGAGCTT GACTCTAGCC TTATTTCCAG CTTCCCTCTG 
CTGAAGGCCC TGAAAACCAG AATCAGTAAC CTGCCCACAG TGAAGAAGTT TCTACAGCCT 
GGCAGCCCAA GGAAGCCTCC CATGGATGAG AAATCTTTAG AAGAATCAAG GAAGATTTTC 
AGGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation.
Haematologica99(1)172-9(2014 Jan)
Bonifazi F,Storci G,Bandini G,Marasco E,Dan E,Zani E,Albani F,Bertoni S,Bontadini A,De Carolis S,Sapienza MR,Rizzi S,Motta MR,Ferioli M,Garagnani P,Cavo M,Mantovani V,Bonaf? M

Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology27(8)3198-208(2013 Aug)
Matsumura T,Imamichi Y,Mizutani T,Ju Y,Yazawa T,Kawabe S,Kanno M,Ayabe T,Katsumata N,Fukami M,Inatani M,Akagi Y,Umezawa A,Ogata T,Miyamoto K

Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.
Drug metabolism and pharmacokinetics26(6)646-58(2011)
Maekawa K,Hamaguchi T,Saito Y,Tatewaki N,Kurose K,Kaniwa N,Eguchi Nakajima T,Kato K,Yamada Y,Shimada Y,Yoshida T,Kamatani N,Ura T,Saito M,Muro K,Fuse N,Yoshino T,Doi T,Otsu A,Saijo N,Sawada J,Okuda H,Matsumura Y

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GSTA2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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