CXCL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CXCL1
Entrez Gene ID	2919
Full Name	C-X-C motif chemokine ligand 1
Synonyms	FSP,GRO1,GROa,MGSA,MGSA-a,NAP-3,SCYB1
General protein information	Preferred Names C-X-C motif chemokine ligand 1 Names growth-regulated alpha protein C-X-C motif chemokine 1 GRO-alpha(1-73) GRO1 oncogene (melanoma growth stimulating activity, alpha) GRO1 oncogene (melanoma growth-stimulating activity) MGSA alpha chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) fibroblast secretory protein melanoma growth stimulating activity, alpha melanoma growth stimulatory activity alpha neutrophil-activating protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q13.3
Summary	This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014].
Disorder MIM:	155730

mRNA and Protein(s)

mRNA	Protein	Name
NM_001511.3	NP_001502.1	growth-regulated alpha protein precursor
NM_001511.4	NP_001502.1	growth-regulated alpha protein precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CXCL1	XP_003950376.1
Homo sapiens (human)	CXCL1	NP_001502.1

Gene Ontology

The following CXCL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CXCL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21597	NM_001511.4 Latest version!	Homo sapiens C-X-C motif chemokine ligand 1 (CXCL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu21597	NM_001511.3	Homo sapiens C-X-C motif chemokine ligand 1 (CXCL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CXCL1 ( NM_001511.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001502.1 Homo sapiens C-X-C motif chemokine ligand 1 (CXCL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21597
Clone ID Related Accession (Same CDS sequence)	NM_001511.3 , NM_001511.4
Accession Version	NM_001511.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 324bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-05
Organism	Homo sapiens(human)
Product	growth-regulated alpha protein precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC092438.5, BM554448.1 and BM996663.1. On Jan 21, 2012 this sequence version replaced NM_001511.2. Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011976.1, ERR279833.4990.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 12949249 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCGCG CTGCTCTCTC CGCCGCCCCC AGCAATCCCC GGCTCCTGCG AGTGGCACTG 
CTGCTCCTGC TCCTGGTAGC CGCTGGCCGG CGCGCAGCAG GAGCGTCCGT GGCCACTGAA 
CTGCGCTGCC AGTGCTTGCA GACCCTGCAG GGAATTCACC CCAAGAACAT CCAAAGTGTG 
AACGTGAAGT CCCCCGGACC CCACTGCGCC CAAACCGAAG TCATAGCCAC ACTCAAGAAT 
GGGCGGAAAG CTTGCCTCAA TCCTGCATCC CCCATAGTTA AGAAAATCAT CGAAAAGATG 
CTGAACAGTG ACAAATCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001502.1
CDS	80..403
Translation	MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN

Target ORF information:

RefSeq Version	NM_001511.3
Organism	Homo sapiens(human)
Definition	Homo sapiens C-X-C motif chemokine ligand 1 (CXCL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001511.3

ORF Insert Sequence:

ATGGCCCGCG CTGCTCTCTC CGCCGCCCCC AGCAATCCCC GGCTCCTGCG AGTGGCACTG 
CTGCTCCTGC TCCTGGTAGC CGCTGGCCGG CGCGCAGCAG GAGCGTCCGT GGCCACTGAA 
CTGCGCTGCC AGTGCTTGCA GACCCTGCAG GGAATTCACC CCAAGAACAT CCAAAGTGTG 
AACGTGAAGT CCCCCGGACC CCACTGCGCC CAAACCGAAG TCATAGCCAC ACTCAAGAAT 
GGGCGGAAAG CTTGCCTCAA TCCTGCATCC CCCATAGTTA AGAAAATCAT CGAAAAGATG 
CTGAACAGTG ACAAATCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CXCL1 ( NM_001511.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001502.1 Homo sapiens C-X-C motif chemokine ligand 1 (CXCL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21597
Clone ID Related Accession (Same CDS sequence)	NM_001511.3 , NM_001511.4
Accession Version	NM_001511.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 324bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	growth-regulated alpha protein precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC092438.5, BM554448.1 and BM996663.1. On May 17, 2019 this sequence version replaced NM_001511.3. Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.234646.1, DRR138517.117119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000395761.4/ ENSP00000379110.3 Protein has antimicrobial activity :: PMID: 12949249 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCGCG CTGCTCTCTC CGCCGCCCCC AGCAATCCCC GGCTCCTGCG AGTGGCACTG 
CTGCTCCTGC TCCTGGTAGC CGCTGGCCGG CGCGCAGCAG GAGCGTCCGT GGCCACTGAA 
CTGCGCTGCC AGTGCTTGCA GACCCTGCAG GGAATTCACC CCAAGAACAT CCAAAGTGTG 
AACGTGAAGT CCCCCGGACC CCACTGCGCC CAAACCGAAG TCATAGCCAC ACTCAAGAAT 
GGGCGGAAAG CTTGCCTCAA TCCTGCATCC CCCATAGTTA AGAAAATCAT CGAAAAGATG 
CTGAACAGTG ACAAATCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001502.1
CDS	79..402
Translation	MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN

Target ORF information:

RefSeq Version	NM_001511.4
Organism	Homo sapiens(human)
Definition	Homo sapiens C-X-C motif chemokine ligand 1 (CXCL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001511.4

ORF Insert Sequence:

ATGGCCCGCG CTGCTCTCTC CGCCGCCCCC AGCAATCCCC GGCTCCTGCG AGTGGCACTG 
CTGCTCCTGC TCCTGGTAGC CGCTGGCCGG CGCGCAGCAG GAGCGTCCGT GGCCACTGAA 
CTGCGCTGCC AGTGCTTGCA GACCCTGCAG GGAATTCACC CCAAGAACAT CCAAAGTGTG 
AACGTGAAGT CCCCCGGACC CCACTGCGCC CAAACCGAAG TCATAGCCAC ACTCAAGAAT 
GGGCGGAAAG CTTGCCTCAA TCCTGCATCC CCCATAGTTA AGAAAATCAT CGAAAAGATG 
CTGAACAGTG ACAAATCCAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

CXCL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報