Gene Symbol | RACGAP1 |
Entrez Gene ID | 29127 |
Full Name | Rac GTPase activating protein 1 |
Synonyms | CYK4,HsCYK-4,ID-GAP,MgcRacGAP |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]. |
Disorder MIM: |