LGALSL cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LGALSL
Entrez Gene ID	29094
Full Name	galectin like
Synonyms	GRP,HSPC159
General protein information	Preferred Names galectin like Names galectin-related protein lectin galactoside-binding-like protein lectin, galactoside binding like
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p14

mRNA and Protein(s)

mRNA	Protein	Name
NM_014181.3	NP_054900.2	galectin-related protein
NM_014181.2	NP_054900.2	galectin-related protein

Pathways from BioSystems

Homologies

Homo sapiens (human)	LGALSL	NP_054900.2
Pan troglodytes (chimpanzee)	LGALSL	XP_525768.3
Canis lupus familiaris (dog)	LGALSL	XP_538509.3
Bos taurus (cattle)	LGALSL	NP_001192760.1
Danio rerio (zebrafish)	lgalsla	NP_001038765.1
Gallus gallus (chicken)	LGALSL	NP_001008456.1
	LGALSL	XP_001085876.2
Mus musculus (house mouse)	Lgalsl	NP_776113.1
Rattus norvegicus (Norway rat)	Lgalsl	NP_001128202.1
Xenopus tropicalis (tropical clawed frog)	lgalsl	NP_001001900.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Lee OH, Kim H, He Q, Baek HJ, Yang D, Chen LY, Liang J, Chae HK, Safari A, Liu D, Songyang Z
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)

Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins.
Zhou D, Ge H, Sun J, Gao Y, Teng M, Niu L
Proteins71(3)1582-8(2008 May)

Gene expression profiling of peripheral blood mononuclear cells from patients with minimal change nephrotic syndrome by cDNA microarrays.
Komatsuda A, Wakui H, Iwamoto K, Harada M, Okumoto Y, Sawada K
American journal of nephrology28(4)539-47(2008)

Expression, purification, crystallization and preliminary X-ray characterization of the GRP carbohydrate-recognition domain from Homo sapiens.
Zhou D, Sun J, Zhao W, Zhang X, Shi Y, Teng M, Niu L, Dong Y, Liu P
Acta crystallographica. Section F, Structural biology and crystallization communications62(Pt 5)474-6(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Galectin-related protein is a novel protein that has a close similarity to galectin sequences but is not a member of the galectin family because of its lack of lactose-binding activity. The crystal structure has been solved.
Title: Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins.

CCL13 and HSPC159 mRNA expressions in PBMC are up-regulated specifically in MCNS patients during the nephrosis phase.
Title: Gene expression profiling of peripheral blood mononuclear cells from patients with minimal change nephrotic syndrome by cDNA microarrays.

Galectin-related protein named GRP comprises only one conserved carbohydrate-recognition domain with 38 additional N-terminal residues. The crystals belong to the monoclinic space group C2.
Title: Expression, purification, crystallization and preliminary X-ray characterization of the GRP carbohydrate-recognition domain from Homo sapiens.

The following LGALSL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LGALSL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30627	NM_014181.3 Latest version!	Homo sapiens galectin like (LGALSL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu30627	NM_014181.2	Homo sapiens galectin like (LGALSL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LGALSL ( NM_014181.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_054900.2 Homo sapiens galectin like (LGALSL), mRNA.

Price & Availability↑

CloneID	OHu30627
Clone ID Related Accession (Same CDS sequence)	NM_014181.3 , NM_014181.2
Accession Version	NM_014181.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	galectin-related protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC008074.3, DR001728.1, BC062691.1, BC036082.1 and AK025603.1. On Nov 22, 2018 this sequence version replaced NM_014181.2. ##Evidence-Data-START## Transcript exon combination :: BC036082.1, SRR3476690.1174056.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000238875.10/ ENSP00000238875.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGGAT CAGTGGCCGA CAGCGATGCC GTGGTGAAAC TAGATGATGG CCATTTAAAC 
AACTCTTTGA GCTCTCCAGT TCAAGCGGAC GTGTACTTCC CACGACTGAT AGTTCCATTT 
TGTGGGCACA TTAAAGGTGG CATGAGACCA GGCAAGAAGG TGTTAGTGAT GGGCATCGTA 
GACCTCAACC CAGAGAGCTT TGCAATCAGC TTGACCTGTG GGGACTCAGA AGACCCTCCT 
GCCGATGTGG CAATCGAACT CAAAGCTGTG TTCACAGATC GGCAGCTACT CAGAAATTCT 
TGTATATCTG GGGAGAGGGG TGAAGAACAG TCAGCAATCC CTTACTTTCC ATTCATTCCA 
GACCAGCCAT TCAGGGTGGA AATTCTTTGT GAGCACCCAC GTTTCCGAGT GTTTGTGGAT 
GGACACCAAC TTTTTGATTT TTACCATCGC ATTCAAACGT TATCTGCAAT TGACACCATA 
AAGATAAATG GAGACCTCCA GATCACCAAG CTTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_054900.2
CDS	385..903
Translation	MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG

Target ORF information:

RefSeq Version	NM_014181.3
Organism	Homo sapiens(human)
Definition	Homo sapiens galectin like (LGALSL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014181.3

ORF Insert Sequence:

ATGGCGGGAT CAGTGGCCGA CAGCGATGCC GTGGTGAAAC TAGATGATGG CCATTTAAAC 
AACTCTTTGA GCTCTCCAGT TCAAGCGGAC GTGTACTTCC CACGACTGAT AGTTCCATTT 
TGTGGGCACA TTAAAGGTGG CATGAGACCA GGCAAGAAGG TGTTAGTGAT GGGCATCGTA 
GACCTCAACC CAGAGAGCTT TGCAATCAGC TTGACCTGTG GGGACTCAGA AGACCCTCCT 
GCCGATGTGG CAATCGAACT CAAAGCTGTG TTCACAGATC GGCAGCTACT CAGAAATTCT 
TGTATATCTG GGGAGAGGGG TGAAGAACAG TCAGCAATCC CTTACTTTCC ATTCATTCCA 
GACCAGCCAT TCAGGGTGGA AATTCTTTGT GAGCACCCAC GTTTCCGAGT GTTTGTGGAT 
GGACACCAAC TTTTTGATTT TTACCATCGC ATTCAAACGT TATCTGCAAT TGACACCATA 
AAGATAAATG GAGACCTCCA GATCACCAAG CTTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LGALSL ( NM_014181.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_054900.2 Homo sapiens galectin like (LGALSL), mRNA.

Price & Availability↑

CloneID	OHu30627
Clone ID Related Accession (Same CDS sequence)	NM_014181.3 , NM_014181.2
Accession Version	NM_014181.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-13
Organism	Homo sapiens(human)
Product	galectin-related protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DR001728.1, BC062691.1, BC036082.1 and AK025603.1. On Aug 22, 2007 this sequence version replaced NM_014181.1. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.259567.1, SRR1803614.183885.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGAT CAGTGGCCGA CAGCGATGCC GTGGTGAAAC TAGATGATGG CCATTTAAAC 
AACTCTTTGA GCTCTCCAGT TCAAGCGGAC GTGTACTTCC CACGACTGAT AGTTCCATTT 
TGTGGGCACA TTAAAGGTGG CATGAGACCA GGCAAGAAGG TGTTAGTGAT GGGCATCGTA 
GACCTCAACC CAGAGAGCTT TGCAATCAGC TTGACCTGTG GGGACTCAGA AGACCCTCCT 
GCCGATGTGG CAATCGAACT CAAAGCTGTG TTCACAGATC GGCAGCTACT CAGAAATTCT 
TGTATATCTG GGGAGAGGGG TGAAGAACAG TCAGCAATCC CTTACTTTCC ATTCATTCCA 
GACCAGCCAT TCAGGGTGGA AATTCTTTGT GAGCACCCAC GTTTCCGAGT GTTTGTGGAT 
GGACACCAAC TTTTTGATTT TTACCATCGC ATTCAAACGT TATCTGCAAT TGACACCATA 
AAGATAAATG GAGACCTCCA GATCACCAAG CTTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_054900.2
CDS	354..872
Translation	MAGSVADSDAVVKLDDGHLNNSLSSPVQADVYFPRLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKINGDLQITKLG

Target ORF information:

RefSeq Version	NM_014181.2
Organism	Homo sapiens(human)
Definition	Homo sapiens galectin like (LGALSL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014181.2

ORF Insert Sequence:

ATGGCGGGAT CAGTGGCCGA CAGCGATGCC GTGGTGAAAC TAGATGATGG CCATTTAAAC 
AACTCTTTGA GCTCTCCAGT TCAAGCGGAC GTGTACTTCC CACGACTGAT AGTTCCATTT 
TGTGGGCACA TTAAAGGTGG CATGAGACCA GGCAAGAAGG TGTTAGTGAT GGGCATCGTA 
GACCTCAACC CAGAGAGCTT TGCAATCAGC TTGACCTGTG GGGACTCAGA AGACCCTCCT 
GCCGATGTGG CAATCGAACT CAAAGCTGTG TTCACAGATC GGCAGCTACT CAGAAATTCT 
TGTATATCTG GGGAGAGGGG TGAAGAACAG TCAGCAATCC CTTACTTTCC ATTCATTCCA 
GACCAGCCAT TCAGGGTGGA AATTCTTTGT GAGCACCCAC GTTTCCGAGT GTTTGTGGAT 
GGACACCAAC TTTTTGATTT TTACCATCGC ATTCAAACGT TATCTGCAAT TGACACCATA 
AAGATAAATG GAGACCTCCA GATCACCAAG CTTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)
Lee OH,Kim H,He Q,Baek HJ,Yang D,Chen LY,Liang J,Chae HK,Safari A,Liu D,Songyang Z

Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins.
Proteins71(3)1582-8(2008 May)
Zhou D,Ge H,Sun J,Gao Y,Teng M,Niu L

Gene expression profiling of peripheral blood mononuclear cells from patients with minimal change nephrotic syndrome by cDNA microarrays.
American journal of nephrology28(4)539-47(2008)
Komatsuda A,Wakui H,Iwamoto K,Harada M,Okumoto Y,Sawada K

Expression, purification, crystallization and preliminary X-ray characterization of the GRP carbohydrate-recognition domain from Homo sapiens.
Acta crystallographica. Section F, Structural biology and crystallization communications62(Pt 5)474-6(2006 May)
Zhou D,Sun J,Zhao W,Zhang X,Shi Y,Teng M,Niu L,Dong Y,Liu P

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LGALSL cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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