Gene Symbol | GRIN1 |
Entrez Gene ID | 2902 |
Full Name | glutamate ionotropic receptor NMDA type subunit 1 |
Synonyms | GluN1,MRD8,NMD-R1,NMDA1,NMDAR1,NR1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Mental retardation, autosomal dominant 8, 614254 (3) |