TPRN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TPRN
Entrez Gene ID	286262
Full Name	taperin
Synonyms	C9orf75,DFNB79
General protein information	Preferred Names taperin Names taperin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.3
Summary	This locus encodes a sensory epithelial protein. It was defined by linkage analysis in three Pakistani families to lie between D9S1818 (centromeric) and D9SH6 (telomeric). Mutations at this locus have been associated with autosomal recessive deafness. [provided by RefSeq, Oct 2010].
Disorder MIM:	613354
Disorder Html:	Deafness, autosomal recessive 79, 613307 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001128228.2	NP_001121700.2	taperin
NM_001128228.3	NP_001121700.2	taperin

Pathways from BioSystems

Homologies

	LOC721581	XP_001117763.1
Bos taurus (cattle)	TPRN	NP_001096820.2
Rattus norvegicus (Norway rat)	Tprn	NP_001019480.2
Xenopus tropicalis (tropical clawed frog)	LOC101731408	XP_004917615.1
Homo sapiens (human)	TPRN	NP_001121700.2
Gallus gallus (chicken)	TPRN	XP_415534.4
Mus musculus (house mouse)	Tprn	NP_780495.2

Gene Ontology
Bibliography

Related articles in PubMed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Yadav L, Tamene F, G??s H, van Drogen A, Katainen R, Aebersold R, Gstaiger M, Varjosalo M
Cell systems4(4)430-444.e5(2017 Apr)

The c.42_52del11 mutation in TPRN and progressive hearing loss in a family from Pakistan.
Bashir R, Imtiaz A, Fatima A, Alam A, Naz S
Biochemical genetics51(5-6)350-7(2013 Jun)

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

Protein phosphatase 1? interacting proteins in the human brain.
Esteves SL, Domingues SC, da Cruz e Silva OA, Fardilha M, da Cruz e Silva EF
Omics : a journal of integrative biology16(1-2)3-17(2012 Jan-Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A Pakistani family in which the affected individuals were homozygous for a pathogenic mutation, c.42_52del11, in TPRN.
Title: The c.42_52del11 mutation in TPRN and progressive hearing loss in a family from Pakistan.

genome-wide homozygosity mapping in a Moroccan family; mapped autosomal-recessive nonsyndromic hearing loss to DFNB79 locus on chromosome 9q34; identified a causative homozygous 11 bp deletion, c.42_52del, in TPRN gene in affected individuals
Title: Mutations in TPRN cause a progressive form of autosomal-recessive nonsyndromic hearing loss.

Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79
Title: Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79.

The following TPRN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TPRN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21934	NM_001128228.3 Latest version!	Homo sapiens taperin (TPRN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$384.30 $549.00
View Old Accession Versions >>
OHu21934	NM_001128228.2	Homo sapiens taperin (TPRN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$384.30 $549.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TPRN ( NM_001128228.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121700.2 Homo sapiens taperin (TPRN), mRNA.

Price & Availability↑

CloneID	OHu21934
Clone ID Related Accession (Same CDS sequence)	NM_001128228.2 , NM_001128228.3
Accession Version	NM_001128228.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	taperin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL929554.20 and BC098411.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 3, 2011 this sequence version replaced XM_003403829.1, NM_001128228.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by mouse NM_175286.4 and supporting mouse transcripts. ##Evidence-Data-START## Transcript exon combination :: BC098411.1, ERR279844.7779.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCC TGGGGCGGCC GGGCTCGGGG CCGCGCGCTG CGGTGCCCGC TTGGAAGCGT 
GAGATCCTGG AGCGGAAGCG GGCCAAGCTA GCCGCGCTGG GCGGGGGCGC GGGGCCCGGG 
GCGGCGGAGC CCGAGCAGCG GGTGCTGGCC GAGAGCCTGG GCCCGCTGCG CGAGAACCCG 
TTCATGCTGC TGGAGGCCGA GCGGCGGCGC GGCGGGGGCG CGGCGGGGGC GCGGCTGCTG 
GAGCGGTACC GCCGCGTGCC TGGCGTGCGC GCCCTCCGCG CCGACAGCGT CCTCATCATC 
GAGACGGTGC CCGGCTTCCC GCCCGCGCCG CCCGCCCCGG GGGCCGCGCA GATCCGCGCC 
GCCGAGGTGC TGGTGTACGG GGCGCCGCCC GGCCGCGTCA GCCGCCTACT GGAGAGGTTC 
GACCCGCCCG CCGCGCCGCG CCGCCGCGGG AGCCCCGAGC GCGCCCGCCC CCCGCCGCCG 
CCGCCGCCGC CCGCGCCGCC CCGGCCCCCG CCCGCGGCCC CCAGCCCGCC CGCCGCGCCC 
GGGCCCCGCG GTGGCGGGGC GAGCCCCGGG GCCCGGCGCA GCGACTTCCT CCAGAAGACC 
GGCAGCAACT CCTTCACCGT CCACCCCCGG GGTCTGCACC GCGGCGCGGG CGCCCGCCTG 
CTCTCCAACG GGCACTCGGC CCCTGAGCCC CGGGCCGGCC CTGCCAACCG CCTCGCGGGC 
TCCCCGCCTG GGTCGGGACA GTGGAAGCCA AAGGTGGAGT CGGGGGATCC CTCCCTCCAC 
CCGCCCCCCA GCCCCGGGAC CCCGAGTGCC ACTCCAGCCT CACCCCCTGC CAGTGCCACT 
CCTAGCCAGC GCCAGTGCGT CTCCGCAGCC ACCAGCACCA ACGACTCCTT CGAGATACGG 
CCGGCCCCCA AGCCAGTTAT GGAGACCATC CCCTTGGGGG ACCTCCAGGC CCGGGCGCTG 
GCCAGCCTCC GCGCAAACTC TCGAAATTCT TTCATGGTCA TCCCCAAGAG CAAGGCCTCC 
GGGGCTCCTC CTCCTGAGGG GAGGCAGTCC GTGGAGCTGC CAAAGGGAGA CCTGGGCCCG 
GCCTCCCCGA GCCAGGAGCT CGGATCCCAG CCGGTGCCTG GAGGGGATGG TGCGCCTGCC 
CTCGGGAAGA GCCCCCTGGA GGTCGAGGCA CAGTGGGCAG TCGAGGAGGG GGCCTGTCCC 
AGGACAGCCA CCGCCCTCGC TGACCGGGCT ATTAGGTGGC AGAGGCCGTC CTCACCGCCC 
CCCTTCCTGC CGGCTGCTTC GGAAGAAGCT GAGCCTGCTG AGGGCCTCAG GGTTCCTGGC 
TTGGCCAAGA ATAGCCGGGA ATATGTGAGG CCGGGGCTGC CTGTCACCTT CATCGATGAG 
GTAGACTCGG AGGAGGCCCC CCAAGCAGCC AAACTACCCT ACCTCCCGCA CCCTGCCAGG 
CCTCTGCACC CTGCCAGGCC CGGGTGCGTG GCAGAGCTTC AGCCCCGGGG CAGCAACACC 
TTCACAGTGG TGCCCAAGAG GAAGCCAGGG ACTCTGCAGG ACCAGCACTT CAGTCAGGCC 
AACAGGGAGC CTCGGCCACG GGAGGCCGAG GAGGAGGAGG CTAGTTGCCT CCTGGGGCCC 
ACGTTGAAGA AGCGCTACCC CACCGTGCAT GAGATCGAGG TGATTGGCGG CTACCTGGCC 
CTGCAGAAGT CCTGCCTCAC CAAGGCTGGC TCCTCAAGAA AGAAGATGAA GATCTCCTTC 
AACGACAAAA GCCTGCAGAC CACATTTGAG TACCCTTCCG AGAGCTCCCT AGAGCAGGAG 
GAAGAGGTGG ACCAGCAGGA GGAGGAGGAG GAGGAGGAGG AGGAAGAGGA AGAGGAGGAA 
GAGGGATCCG GCTCAGAGGA GAAGCCCTTT GCACTCTTCC TGCCCCGGGC CACGTTTGTG 
AGCAGCGTGA GACCCGAGAG CTCTCGGCTG CCAGAGGGTA GCTCAGGCCT GTCCAGCTAC 
ACCCCGAAGC ACTCTGTGGC CTTCAGCAAG TGGCAGGAGC AGGCGCTGGA GCAGGCCCCG 
AGGGAGGCAG AGCCCCCGCC CGTGGAGGCC ATGCTCACAC CCGCCAGTCA GAATGACCTC 
TCGGACTTCC GCAGCGAGCC AGCCCTGTAT TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121700.2
CDS	1..2136
Translation	MAALGRPGSGPRAAVPAWKREILERKRAKLAALGGGAGPGAAEPEQRVLAESLGPLRENPFMLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYTPKHSVAFSKWQEQALEQAPREAEPPPVEAMLTPASQNDLSDFRSEPALYF

Target ORF information:

RefSeq Version	NM_001128228.2
Organism	Homo sapiens(human)
Definition	Homo sapiens taperin (TPRN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128228.2

ORF Insert Sequence:

ATGGCCGCCC TGGGGCGGCC GGGCTCGGGG CCGCGCGCTG CGGTGCCCGC TTGGAAGCGT 
GAGATCCTGG AGCGGAAGCG GGCCAAGCTA GCCGCGCTGG GCGGGGGCGC GGGGCCCGGG 
GCGGCGGAGC CCGAGCAGCG GGTGCTGGCC GAGAGCCTGG GCCCGCTGCG CGAGAACCCG 
TTCATGCTGC TGGAGGCCGA GCGGCGGCGC GGCGGGGGCG CGGCGGGGGC GCGGCTGCTG 
GAGCGGTACC GCCGCGTGCC TGGCGTGCGC GCCCTCCGCG CCGACAGCGT CCTCATCATC 
GAGACGGTGC CCGGCTTCCC GCCCGCGCCG CCCGCCCCGG GGGCCGCGCA GATCCGCGCC 
GCCGAGGTGC TGGTGTACGG GGCGCCGCCC GGCCGCGTCA GCCGCCTACT GGAGAGGTTC 
GACCCGCCCG CCGCGCCGCG CCGCCGCGGG AGCCCCGAGC GCGCCCGCCC CCCGCCGCCG 
CCGCCGCCGC CCGCGCCGCC CCGGCCCCCG CCCGCGGCCC CCAGCCCGCC CGCCGCGCCC 
GGGCCCCGCG GTGGCGGGGC GAGCCCCGGG GCCCGGCGCA GCGACTTCCT CCAGAAGACC 
GGCAGCAACT CCTTCACCGT CCACCCCCGG GGTCTGCACC GCGGCGCGGG CGCCCGCCTG 
CTCTCCAACG GGCACTCGGC CCCTGAGCCC CGGGCCGGCC CTGCCAACCG CCTCGCGGGC 
TCCCCGCCTG GGTCGGGACA GTGGAAGCCA AAGGTGGAGT CGGGGGATCC CTCCCTCCAC 
CCGCCCCCCA GCCCCGGGAC CCCGAGTGCC ACTCCAGCCT CACCCCCTGC CAGTGCCACT 
CCTAGCCAGC GCCAGTGCGT CTCCGCAGCC ACCAGCACCA ACGACTCCTT CGAGATACGG 
CCGGCCCCCA AGCCAGTTAT GGAGACCATC CCCTTGGGGG ACCTCCAGGC CCGGGCGCTG 
GCCAGCCTCC GCGCAAACTC TCGAAATTCT TTCATGGTCA TCCCCAAGAG CAAGGCCTCC 
GGGGCTCCTC CTCCTGAGGG GAGGCAGTCC GTGGAGCTGC CAAAGGGAGA CCTGGGCCCG 
GCCTCCCCGA GCCAGGAGCT CGGATCCCAG CCGGTGCCTG GAGGGGATGG TGCGCCTGCC 
CTCGGGAAGA GCCCCCTGGA GGTCGAGGCA CAGTGGGCAG TCGAGGAGGG GGCCTGTCCC 
AGGACAGCCA CCGCCCTCGC TGACCGGGCT ATTAGGTGGC AGAGGCCGTC CTCACCGCCC 
CCCTTCCTGC CGGCTGCTTC GGAAGAAGCT GAGCCTGCTG AGGGCCTCAG GGTTCCTGGC 
TTGGCCAAGA ATAGCCGGGA ATATGTGAGG CCGGGGCTGC CTGTCACCTT CATCGATGAG 
GTAGACTCGG AGGAGGCCCC CCAAGCAGCC AAACTACCCT ACCTCCCGCA CCCTGCCAGG 
CCTCTGCACC CTGCCAGGCC CGGGTGCGTG GCAGAGCTTC AGCCCCGGGG CAGCAACACC 
TTCACAGTGG TGCCCAAGAG GAAGCCAGGG ACTCTGCAGG ACCAGCACTT CAGTCAGGCC 
AACAGGGAGC CTCGGCCACG GGAGGCCGAG GAGGAGGAGG CTAGTTGCCT CCTGGGGCCC 
ACGTTGAAGA AGCGCTACCC CACCGTGCAT GAGATCGAGG TGATTGGCGG CTACCTGGCC 
CTGCAGAAGT CCTGCCTCAC CAAGGCTGGC TCCTCAAGAA AGAAGATGAA GATCTCCTTC 
AACGACAAAA GCCTGCAGAC CACATTTGAG TACCCTTCCG AGAGCTCCCT AGAGCAGGAG 
GAAGAGGTGG ACCAGCAGGA GGAGGAGGAG GAGGAGGAGG AGGAAGAGGA AGAGGAGGAA 
GAGGGATCCG GCTCAGAGGA GAAGCCCTTT GCACTCTTCC TGCCCCGGGC CACGTTTGTG 
AGCAGCGTGA GACCCGAGAG CTCTCGGCTG CCAGAGGGTA GCTCAGGCCT GTCCAGCTAC 
ACCCCGAAGC ACTCTGTGGC CTTCAGCAAG TGGCAGGAGC AGGCGCTGGA GCAGGCCCCG 
AGGGAGGCAG AGCCCCCGCC CGTGGAGGCC ATGCTCACAC CCGCCAGTCA GAATGACCTC 
TCGGACTTCC GCAGCGAGCC AGCCCTGTAT TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TPRN ( NM_001128228.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121700.2 Homo sapiens taperin (TPRN), mRNA.

Price & Availability↑

CloneID	OHu21934
Clone ID Related Accession (Same CDS sequence)	NM_001128228.2 , NM_001128228.3
Accession Version	NM_001128228.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	taperin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL929554.20 and BC098411.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001128228.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by mouse NM_175286.4 and supporting mouse transcripts. ##Evidence-Data-START## Transcript exon combination :: BC111500.1, BC098411.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000409012.6/ ENSP00000387100.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGCCC TGGGGCGGCC GGGCTCGGGG CCGCGCGCTG CGGTGCCCGC TTGGAAGCGT 
GAGATCCTGG AGCGGAAGCG GGCCAAGCTA GCCGCGCTGG GCGGGGGCGC GGGGCCCGGG 
GCGGCGGAGC CCGAGCAGCG GGTGCTGGCC GAGAGCCTGG GCCCGCTGCG CGAGAACCCG 
TTCATGCTGC TGGAGGCCGA GCGGCGGCGC GGCGGGGGCG CGGCGGGGGC GCGGCTGCTG 
GAGCGGTACC GCCGCGTGCC TGGCGTGCGC GCCCTCCGCG CCGACAGCGT CCTCATCATC 
GAGACGGTGC CCGGCTTCCC GCCCGCGCCG CCCGCCCCGG GGGCCGCGCA GATCCGCGCC 
GCCGAGGTGC TGGTGTACGG GGCGCCGCCC GGCCGCGTCA GCCGCCTACT GGAGAGGTTC 
GACCCGCCCG CCGCGCCGCG CCGCCGCGGG AGCCCCGAGC GCGCCCGCCC CCCGCCGCCG 
CCGCCGCCGC CCGCGCCGCC CCGGCCCCCG CCCGCGGCCC CCAGCCCGCC CGCCGCGCCC 
GGGCCCCGCG GTGGCGGGGC GAGCCCCGGG GCCCGGCGCA GCGACTTCCT CCAGAAGACC 
GGCAGCAACT CCTTCACCGT CCACCCCCGG GGTCTGCACC GCGGCGCGGG CGCCCGCCTG 
CTCTCCAACG GGCACTCGGC CCCTGAGCCC CGGGCCGGCC CTGCCAACCG CCTCGCGGGC 
TCCCCGCCTG GGTCGGGACA GTGGAAGCCA AAGGTGGAGT CGGGGGATCC CTCCCTCCAC 
CCGCCCCCCA GCCCCGGGAC CCCGAGTGCC ACTCCAGCCT CACCCCCTGC CAGTGCCACT 
CCTAGCCAGC GCCAGTGCGT CTCCGCAGCC ACCAGCACCA ACGACTCCTT CGAGATACGG 
CCGGCCCCCA AGCCAGTTAT GGAGACCATC CCCTTGGGGG ACCTCCAGGC CCGGGCGCTG 
GCCAGCCTCC GCGCAAACTC TCGAAATTCT TTCATGGTCA TCCCCAAGAG CAAGGCCTCC 
GGGGCTCCTC CTCCTGAGGG GAGGCAGTCC GTGGAGCTGC CAAAGGGAGA CCTGGGCCCG 
GCCTCCCCGA GCCAGGAGCT CGGATCCCAG CCGGTGCCTG GAGGGGATGG TGCGCCTGCC 
CTCGGGAAGA GCCCCCTGGA GGTCGAGGCA CAGTGGGCAG TCGAGGAGGG GGCCTGTCCC 
AGGACAGCCA CCGCCCTCGC TGACCGGGCT ATTAGGTGGC AGAGGCCGTC CTCACCGCCC 
CCCTTCCTGC CGGCTGCTTC GGAAGAAGCT GAGCCTGCTG AGGGCCTCAG GGTTCCTGGC 
TTGGCCAAGA ATAGCCGGGA ATATGTGAGG CCGGGGCTGC CTGTCACCTT CATCGATGAG 
GTAGACTCGG AGGAGGCCCC CCAAGCAGCC AAACTACCCT ACCTCCCGCA CCCTGCCAGG 
CCTCTGCACC CTGCCAGGCC CGGGTGCGTG GCAGAGCTTC AGCCCCGGGG CAGCAACACC 
TTCACAGTGG TGCCCAAGAG GAAGCCAGGG ACTCTGCAGG ACCAGCACTT CAGTCAGGCC 
AACAGGGAGC CTCGGCCACG GGAGGCCGAG GAGGAGGAGG CTAGTTGCCT CCTGGGGCCC 
ACGTTGAAGA AGCGCTACCC CACCGTGCAT GAGATCGAGG TGATTGGCGG CTACCTGGCC 
CTGCAGAAGT CCTGCCTCAC CAAGGCTGGC TCCTCAAGAA AGAAGATGAA GATCTCCTTC 
AACGACAAAA GCCTGCAGAC CACATTTGAG TACCCTTCCG AGAGCTCCCT AGAGCAGGAG 
GAAGAGGTGG ACCAGCAGGA GGAGGAGGAG GAGGAGGAGG AGGAAGAGGA AGAGGAGGAA 
GAGGGATCCG GCTCAGAGGA GAAGCCCTTT GCACTCTTCC TGCCCCGGGC CACGTTTGTG 
AGCAGCGTGA GACCCGAGAG CTCTCGGCTG CCAGAGGGTA GCTCAGGCCT GTCCAGCTAC 
ACCCCGAAGC ACTCTGTGGC CTTCAGCAAG TGGCAGGAGC AGGCGCTGGA GCAGGCCCCG 
AGGGAGGCAG AGCCCCCGCC CGTGGAGGCC ATGCTCACAC CCGCCAGTCA GAATGACCTC 
TCGGACTTCC GCAGCGAGCC AGCCCTGTAT TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121700.2
CDS	31..2166
Translation	MAALGRPGSGPRAAVPAWKREILERKRAKLAALGGGAGPGAAEPEQRVLAESLGPLRENPFMLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYTPKHSVAFSKWQEQALEQAPREAEPPPVEAMLTPASQNDLSDFRSEPALYF

Target ORF information:

RefSeq Version	NM_001128228.3
Organism	Homo sapiens(human)
Definition	Homo sapiens taperin (TPRN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128228.3

ORF Insert Sequence:

ATGGCCGCCC TGGGGCGGCC GGGCTCGGGG CCGCGCGCTG CGGTGCCCGC TTGGAAGCGT 
GAGATCCTGG AGCGGAAGCG GGCCAAGCTA GCCGCGCTGG GCGGGGGCGC GGGGCCCGGG 
GCGGCGGAGC CCGAGCAGCG GGTGCTGGCC GAGAGCCTGG GCCCGCTGCG CGAGAACCCG 
TTCATGCTGC TGGAGGCCGA GCGGCGGCGC GGCGGGGGCG CGGCGGGGGC GCGGCTGCTG 
GAGCGGTACC GCCGCGTGCC TGGCGTGCGC GCCCTCCGCG CCGACAGCGT CCTCATCATC 
GAGACGGTGC CCGGCTTCCC GCCCGCGCCG CCCGCCCCGG GGGCCGCGCA GATCCGCGCC 
GCCGAGGTGC TGGTGTACGG GGCGCCGCCC GGCCGCGTCA GCCGCCTACT GGAGAGGTTC 
GACCCGCCCG CCGCGCCGCG CCGCCGCGGG AGCCCCGAGC GCGCCCGCCC CCCGCCGCCG 
CCGCCGCCGC CCGCGCCGCC CCGGCCCCCG CCCGCGGCCC CCAGCCCGCC CGCCGCGCCC 
GGGCCCCGCG GTGGCGGGGC GAGCCCCGGG GCCCGGCGCA GCGACTTCCT CCAGAAGACC 
GGCAGCAACT CCTTCACCGT CCACCCCCGG GGTCTGCACC GCGGCGCGGG CGCCCGCCTG 
CTCTCCAACG GGCACTCGGC CCCTGAGCCC CGGGCCGGCC CTGCCAACCG CCTCGCGGGC 
TCCCCGCCTG GGTCGGGACA GTGGAAGCCA AAGGTGGAGT CGGGGGATCC CTCCCTCCAC 
CCGCCCCCCA GCCCCGGGAC CCCGAGTGCC ACTCCAGCCT CACCCCCTGC CAGTGCCACT 
CCTAGCCAGC GCCAGTGCGT CTCCGCAGCC ACCAGCACCA ACGACTCCTT CGAGATACGG 
CCGGCCCCCA AGCCAGTTAT GGAGACCATC CCCTTGGGGG ACCTCCAGGC CCGGGCGCTG 
GCCAGCCTCC GCGCAAACTC TCGAAATTCT TTCATGGTCA TCCCCAAGAG CAAGGCCTCC 
GGGGCTCCTC CTCCTGAGGG GAGGCAGTCC GTGGAGCTGC CAAAGGGAGA CCTGGGCCCG 
GCCTCCCCGA GCCAGGAGCT CGGATCCCAG CCGGTGCCTG GAGGGGATGG TGCGCCTGCC 
CTCGGGAAGA GCCCCCTGGA GGTCGAGGCA CAGTGGGCAG TCGAGGAGGG GGCCTGTCCC 
AGGACAGCCA CCGCCCTCGC TGACCGGGCT ATTAGGTGGC AGAGGCCGTC CTCACCGCCC 
CCCTTCCTGC CGGCTGCTTC GGAAGAAGCT GAGCCTGCTG AGGGCCTCAG GGTTCCTGGC 
TTGGCCAAGA ATAGCCGGGA ATATGTGAGG CCGGGGCTGC CTGTCACCTT CATCGATGAG 
GTAGACTCGG AGGAGGCCCC CCAAGCAGCC AAACTACCCT ACCTCCCGCA CCCTGCCAGG 
CCTCTGCACC CTGCCAGGCC CGGGTGCGTG GCAGAGCTTC AGCCCCGGGG CAGCAACACC 
TTCACAGTGG TGCCCAAGAG GAAGCCAGGG ACTCTGCAGG ACCAGCACTT CAGTCAGGCC 
AACAGGGAGC CTCGGCCACG GGAGGCCGAG GAGGAGGAGG CTAGTTGCCT CCTGGGGCCC 
ACGTTGAAGA AGCGCTACCC CACCGTGCAT GAGATCGAGG TGATTGGCGG CTACCTGGCC 
CTGCAGAAGT CCTGCCTCAC CAAGGCTGGC TCCTCAAGAA AGAAGATGAA GATCTCCTTC 
AACGACAAAA GCCTGCAGAC CACATTTGAG TACCCTTCCG AGAGCTCCCT AGAGCAGGAG 
GAAGAGGTGG ACCAGCAGGA GGAGGAGGAG GAGGAGGAGG AGGAAGAGGA AGAGGAGGAA 
GAGGGATCCG GCTCAGAGGA GAAGCCCTTT GCACTCTTCC TGCCCCGGGC CACGTTTGTG 
AGCAGCGTGA GACCCGAGAG CTCTCGGCTG CCAGAGGGTA GCTCAGGCCT GTCCAGCTAC 
ACCCCGAAGC ACTCTGTGGC CTTCAGCAAG TGGCAGGAGC AGGCGCTGGA GCAGGCCCCG 
AGGGAGGCAG AGCCCCCGCC CGTGGAGGCC ATGCTCACAC CCGCCAGTCA GAATGACCTC 
TCGGACTTCC GCAGCGAGCC AGCCCTGTAT TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Cell systems4(4)430-444.e5(2017 Apr)
Yadav L,Tamene F,G??s H,van Drogen A,Katainen R,Aebersold R,Gstaiger M,Varjosalo M

The c.42_52del11 mutation in TPRN and progressive hearing loss in a family from Pakistan.
Biochemical genetics51(5-6)350-7(2013 Jun)
Bashir R,Imtiaz A,Fatima A,Alam A,Naz S

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

Protein phosphatase 1? interacting proteins in the human brain.
Omics : a journal of integrative biology16(1-2)3-17(2012 Jan-Feb)
Esteves SL,Domingues SC,da Cruz e Silva OA,Fardilha M,da Cruz e Silva EF

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TPRN cDNA ORF clone, Homo sapiens(human)

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