Gene Symbol | CRB2 |
Entrez Gene ID | 286204 |
Full Name | crumbs 2, cell polarity complex component |
Synonyms | FSGS9,VMCKD |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of a family of proteins that are components of the Crumbs cell polarity complex. In mammals, members of this family are thought to play a role in many cellular processes in early embryonic development. A similar protein in Drosophila determines apicobasal polarity in embryonic epithelial cells. Mutations in this gene are associated with focal segmental glomerulosclerosis 9, and with ventriculomegaly with cystic kidney disease. [provided by RefSeq, Aug 2016]. |
Disorder MIM: | |
Disorder Html: | Focal segmental glomerulosclerosis 9, 616220 (3); Ventriculomegaly with cystic kidney disease, 219730 (3) |