GPR37 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPR37
Entrez Gene ID	2861
Full Name	G protein-coupled receptor 37
Synonyms	EDNRBL,PAELR,hET(B)R-LP
General protein information	Preferred Names G protein-coupled receptor 37 Names prosaposin receptor GPR37 ETBR-LP-1 G protein-coupled receptor 37 (endothelin receptor type B-like) Parkin-associated endothelin receptor-like receptor endothelin B receptor-like protein 1 probable G-protein coupled receptor 37
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 7 Map Location: 7q31.33
Summary	This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012].
Disorder MIM:	602583

mRNA and Protein(s)

mRNA	Protein	Name
NM_005302.4	NP_005293.1	prosaposin receptor GPR37 precursor
NM_005302.5	NP_005293.1	prosaposin receptor GPR37 precursor
NM_005302.3	NP_005293.1	prosaposin receptor GPR37 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GPR37	XP_001149034.1
Canis lupus familiaris (dog)	GPR37	XP_539394.1
Mus musculus (house mouse)	Gpr37	NP_034468.2
Danio rerio (zebrafish)	LOC100537916	XP_003201499.2
Homo sapiens (human)	GPR37	NP_005293.1
	GPR37	XP_001087229.1
Bos taurus (cattle)	GPR37	NP_001069437.1
Rattus norvegicus (Norway rat)	Gpr37	NP_476549.1
Gallus gallus (chicken)	GPR37	NP_001075168.1

Gene Ontology
Bibliography

Related articles in PubMed

Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.
Berger BS, Acebron SP, Herbst J, Koch S, Niehrs C
EMBO reports18(5)712-725(2017 May)

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.
Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gand?a J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, Morat? X, Otasek D, Kobayashi H, Menendez J, Auerbach D, Angers S, Pr?ulj N, Bouvier M, Babu M, Ciruela F, Jockers R, Jurisica I, Stagljar I
Molecular systems biology13(3)918(2017 03)

REG4 promotes peritoneal metastasis of gastric cancer through GPR37.
Wang H, Hu L, Zang M, Zhang B, Duan Y, Fan Z, Li J, Su L, Yan M, Zhu Z, Liu B, Yang Q
Oncotarget7(19)27874-88(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

REG4 promotes peritoneal metastasis of gastric cancer through GPR37 and triggers a positive feedback loop.
Title: REG4 promotes peritoneal metastasis of gastric cancer through GPR37.

GPR37 was shown to be a component of the CASPR2-MUPP1 complex in brain.
Title: CASPR2 forms a complex with GPR37 via MUPP1 but not with GPR37(R558Q), an autism spectrum disorder-related mutation.

GPR37 may play an important role in the pathogenesis of hepatocellular carcinoma by affecting the proliferation of HCC cells.
Title: A low level of GPR37 is associated with human hepatocellular carcinoma progression and poor patient survival.

Positive role of GPR37 in the proliferation of multiple myeloma cells.
Title: The role of the orphan G protein-coupled receptor 37 (GPR37) in multiple myeloma cells.

GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.
Title: GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.

The following GPR37 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPR37 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14150	NM_005302.5 Latest version!	Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu14150	NM_005302.4	Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
OHu14150	NM_005302.3	Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPR37 ( NM_005302.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_005293.1 Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.

Price & Availability↑

CloneID	OHu14150
Clone ID Related Accession (Same CDS sequence)	NM_005302.4 , NM_005302.5 , NM_005302.3
Accession Version	NM_005302.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	prosaposin receptor GPR37 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004925.1 and AF017262.1. On May 17, 2019 this sequence version replaced NM_005302.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.136430.1, SRR1803611.188468.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000303921.3/ ENSP00000306449.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGAGCCC CGGGCGCGCT TCTCGCCCGC ATGTCGCGGC TACTGCTTCT GCTACTGCTC 
AAGGTGTCTG CCTCTTCTGC CCTCGGGGTC GCCCCTGCGT CCAGAAACGA AACTTGTCTG 
GGGGAGAGCT GTGCACCTAC AGTGATCCAG CGCCGCGGCA GGGACGCCTG GGGACCGGGA 
AATTCTGCAA GAGACGTTCT GCGAGCCCGA GCACCCAGGG AGGAGCAGGG GGCAGCGTTT 
CTTGCGGGAC CCTCCTGGGA CCTGCCGGCG GCCCCGGGCC GTGACCCGGC TGCAGGCAGA 
GGGGCGGAGG CGTCGGCAGC CGGACCCCCG GGACCTCCAA CCAGGCCACC TGGCCCCTGG 
AGGTGGAAAG GTGCTCGGGG TCAGGAGCCT TCTGAAACTT TGGGGAGAGG GAACCCCACG 
GCCCTCCAGC TCTTCCTTCA GATCTCAGAG GAGGAAGAGA AGGGTCCCAG AGGCGCTGGC 
ATTTCCGGGC GTAGCCAGGA GCAGAGTGTG AAGACAGTCC CCGGAGCCAG CGATCTTTTT 
TACTGGCCAA GGAGAGCCGG GAAACTCCAG GGTTCCCACC ACAAGCCCCT GTCCAAGACG 
GCCAATGGAC TGGCGGGGCA CGAAGGGTGG ACAATTGCAC TCCCGGGCCG GGCGCTGGCC 
CAGAATGGAT CCTTGGGTGA AGGAATCCAT GAGCCTGGGG GTCCCCGCCG GGGAAACAGC 
ACGAACCGGC GTGTGAGACT GAAGAACCCC TTCTACCCGC TGACCCAGGA GTCCTATGGA 
GCCTACGCGG TCATGTGTCT GTCCGTGGTG ATCTTCGGGA CCGGCATCAT TGGCAACCTG 
GCGGTGATGT GCATCGTGTG CCACAACTAC TACATGCGGA GCATCTCCAA CTCCCTCTTG 
GCCAACCTGG CCTTCTGGGA CTTTCTCATC ATCTTCTTCT GCCTTCCGCT GGTCATCTTC 
CACGAGCTGA CCAAGAAGTG GCTGCTGGAG GACTTCTCCT GCAAGATCGT GCCCTATATA 
GAGGTCGCTT CTCTGGGAGT CACCACTTTC ACCTTATGTG CTCTGTGCAT AGACCGCTTC 
CGTGCTGCCA CCAACGTACA GATGTACTAC GAAATGATCG AAAACTGTTC CTCAACAACT 
GCCAAACTTG CTGTTATATG GGTGGGAGCT CTATTGTTAG CACTTCCAGA AGTTGTTCTC 
CGCCAGCTGA GCAAGGAGGA TTTGGGGTTT AGTGGCCGAG CTCCGGCAGA AAGGTGCATT 
ATTAAGATCT CTCCTGATTT ACCAGACACC ATCTATGTTC TAGCCCTCAC CTACGACAGT 
GCGAGACTGT GGTGGTATTT TGGCTGTTAC TTTTGTTTGC CCACGCTTTT CACCATCACC 
TGCTCTCTAG TGACTGCGAG GAAAATCCGC AAAGCAGAGA AAGCCTGTAC CCGAGGGAAT 
AAACGGCAGA TTCAACTAGA GAGTCAGATG AACTGTACAG TAGTGGCACT GACCATTTTA 
TATGGATTTT GCATTATTCC TGAAAATATC TGCAACATTG TTACTGCCTA CATGGCTACA 
GGGGTTTCAC AGCAGACAAT GGACCTCCTT AATATCATCA GCCAGTTCCT TTTGTTCTTT 
AAGTCCTGTG TCACCCCAGT CCTCCTTTTC TGTCTCTGCA AACCCTTCAG TCGGGCCTTC 
ATGGAGTGCT GCTGCTGTTG CTGTGAGGAA TGCATTCAGA AGTCTTCAAC GGTGACCAGT 
GATGACAATG ACAACGAGTA CACCACGGAA CTCGAACTCT CGCCTTTCAG TACCATACGC 
CGTGAAATGT CCACTTTTGC TTCTGTCGGA ACTCATTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005293.1
CDS	817..2658
Translation	MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPTVIQRRGRDAWGPGNSARDVLRARAPREEQGAAFLAGPSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLFYWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC

Target ORF information:

RefSeq Version	NM_005302.5
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005302.5

ORF Insert Sequence:

ATGCGAGCCC CGGGCGCGCT TCTCGCCCGC ATGTCGCGGC TACTGCTTCT GCTACTGCTC 
AAGGTGTCTG CCTCTTCTGC CCTCGGGGTC GCCCCTGCGT CCAGAAACGA AACTTGTCTG 
GGGGAGAGCT GTGCACCTAC AGTGATCCAG CGCCGCGGCA GGGACGCCTG GGGACCGGGA 
AATTCTGCAA GAGACGTTCT GCGAGCCCGA GCACCCAGGG AGGAGCAGGG GGCAGCGTTT 
CTTGCGGGAC CCTCCTGGGA CCTGCCGGCG GCCCCGGGCC GTGACCCGGC TGCAGGCAGA 
GGGGCGGAGG CGTCGGCAGC CGGACCCCCG GGACCTCCAA CCAGGCCACC TGGCCCCTGG 
AGGTGGAAAG GTGCTCGGGG TCAGGAGCCT TCTGAAACTT TGGGGAGAGG GAACCCCACG 
GCCCTCCAGC TCTTCCTTCA GATCTCAGAG GAGGAAGAGA AGGGTCCCAG AGGCGCTGGC 
ATTTCCGGGC GTAGCCAGGA GCAGAGTGTG AAGACAGTCC CCGGAGCCAG CGATCTTTTT 
TACTGGCCAA GGAGAGCCGG GAAACTCCAG GGTTCCCACC ACAAGCCCCT GTCCAAGACG 
GCCAATGGAC TGGCGGGGCA CGAAGGGTGG ACAATTGCAC TCCCGGGCCG GGCGCTGGCC 
CAGAATGGAT CCTTGGGTGA AGGAATCCAT GAGCCTGGGG GTCCCCGCCG GGGAAACAGC 
ACGAACCGGC GTGTGAGACT GAAGAACCCC TTCTACCCGC TGACCCAGGA GTCCTATGGA 
GCCTACGCGG TCATGTGTCT GTCCGTGGTG ATCTTCGGGA CCGGCATCAT TGGCAACCTG 
GCGGTGATGT GCATCGTGTG CCACAACTAC TACATGCGGA GCATCTCCAA CTCCCTCTTG 
GCCAACCTGG CCTTCTGGGA CTTTCTCATC ATCTTCTTCT GCCTTCCGCT GGTCATCTTC 
CACGAGCTGA CCAAGAAGTG GCTGCTGGAG GACTTCTCCT GCAAGATCGT GCCCTATATA 
GAGGTCGCTT CTCTGGGAGT CACCACTTTC ACCTTATGTG CTCTGTGCAT AGACCGCTTC 
CGTGCTGCCA CCAACGTACA GATGTACTAC GAAATGATCG AAAACTGTTC CTCAACAACT 
GCCAAACTTG CTGTTATATG GGTGGGAGCT CTATTGTTAG CACTTCCAGA AGTTGTTCTC 
CGCCAGCTGA GCAAGGAGGA TTTGGGGTTT AGTGGCCGAG CTCCGGCAGA AAGGTGCATT 
ATTAAGATCT CTCCTGATTT ACCAGACACC ATCTATGTTC TAGCCCTCAC CTACGACAGT 
GCGAGACTGT GGTGGTATTT TGGCTGTTAC TTTTGTTTGC CCACGCTTTT CACCATCACC 
TGCTCTCTAG TGACTGCGAG GAAAATCCGC AAAGCAGAGA AAGCCTGTAC CCGAGGGAAT 
AAACGGCAGA TTCAACTAGA GAGTCAGATG AACTGTACAG TAGTGGCACT GACCATTTTA 
TATGGATTTT GCATTATTCC TGAAAATATC TGCAACATTG TTACTGCCTA CATGGCTACA 
GGGGTTTCAC AGCAGACAAT GGACCTCCTT AATATCATCA GCCAGTTCCT TTTGTTCTTT 
AAGTCCTGTG TCACCCCAGT CCTCCTTTTC TGTCTCTGCA AACCCTTCAG TCGGGCCTTC 
ATGGAGTGCT GCTGCTGTTG CTGTGAGGAA TGCATTCAGA AGTCTTCAAC GGTGACCAGT 
GATGACAATG ACAACGAGTA CACCACGGAA CTCGAACTCT CGCCTTTCAG TACCATACGC 
CGTGAAATGT CCACTTTTGC TTCTGTCGGA ACTCATTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPR37 ( NM_005302.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_005293.1 Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.

Price & Availability↑

CloneID	OHu14150
Clone ID Related Accession (Same CDS sequence)	NM_005302.4 , NM_005302.5 , NM_005302.3
Accession Version	NM_005302.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	prosaposin receptor GPR37 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004925.1 and AF017262.1. On Jul 19, 2017 this sequence version replaced NM_005302.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.136430.1, SRR1660805.155743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGAGCCC CGGGCGCGCT TCTCGCCCGC ATGTCGCGGC TACTGCTTCT GCTACTGCTC 
AAGGTGTCTG CCTCTTCTGC CCTCGGGGTC GCCCCTGCGT CCAGAAACGA AACTTGTCTG 
GGGGAGAGCT GTGCACCTAC AGTGATCCAG CGCCGCGGCA GGGACGCCTG GGGACCGGGA 
AATTCTGCAA GAGACGTTCT GCGAGCCCGA GCACCCAGGG AGGAGCAGGG GGCAGCGTTT 
CTTGCGGGAC CCTCCTGGGA CCTGCCGGCG GCCCCGGGCC GTGACCCGGC TGCAGGCAGA 
GGGGCGGAGG CGTCGGCAGC CGGACCCCCG GGACCTCCAA CCAGGCCACC TGGCCCCTGG 
AGGTGGAAAG GTGCTCGGGG TCAGGAGCCT TCTGAAACTT TGGGGAGAGG GAACCCCACG 
GCCCTCCAGC TCTTCCTTCA GATCTCAGAG GAGGAAGAGA AGGGTCCCAG AGGCGCTGGC 
ATTTCCGGGC GTAGCCAGGA GCAGAGTGTG AAGACAGTCC CCGGAGCCAG CGATCTTTTT 
TACTGGCCAA GGAGAGCCGG GAAACTCCAG GGTTCCCACC ACAAGCCCCT GTCCAAGACG 
GCCAATGGAC TGGCGGGGCA CGAAGGGTGG ACAATTGCAC TCCCGGGCCG GGCGCTGGCC 
CAGAATGGAT CCTTGGGTGA AGGAATCCAT GAGCCTGGGG GTCCCCGCCG GGGAAACAGC 
ACGAACCGGC GTGTGAGACT GAAGAACCCC TTCTACCCGC TGACCCAGGA GTCCTATGGA 
GCCTACGCGG TCATGTGTCT GTCCGTGGTG ATCTTCGGGA CCGGCATCAT TGGCAACCTG 
GCGGTGATGT GCATCGTGTG CCACAACTAC TACATGCGGA GCATCTCCAA CTCCCTCTTG 
GCCAACCTGG CCTTCTGGGA CTTTCTCATC ATCTTCTTCT GCCTTCCGCT GGTCATCTTC 
CACGAGCTGA CCAAGAAGTG GCTGCTGGAG GACTTCTCCT GCAAGATCGT GCCCTATATA 
GAGGTCGCTT CTCTGGGAGT CACCACTTTC ACCTTATGTG CTCTGTGCAT AGACCGCTTC 
CGTGCTGCCA CCAACGTACA GATGTACTAC GAAATGATCG AAAACTGTTC CTCAACAACT 
GCCAAACTTG CTGTTATATG GGTGGGAGCT CTATTGTTAG CACTTCCAGA AGTTGTTCTC 
CGCCAGCTGA GCAAGGAGGA TTTGGGGTTT AGTGGCCGAG CTCCGGCAGA AAGGTGCATT 
ATTAAGATCT CTCCTGATTT ACCAGACACC ATCTATGTTC TAGCCCTCAC CTACGACAGT 
GCGAGACTGT GGTGGTATTT TGGCTGTTAC TTTTGTTTGC CCACGCTTTT CACCATCACC 
TGCTCTCTAG TGACTGCGAG GAAAATCCGC AAAGCAGAGA AAGCCTGTAC CCGAGGGAAT 
AAACGGCAGA TTCAACTAGA GAGTCAGATG AACTGTACAG TAGTGGCACT GACCATTTTA 
TATGGATTTT GCATTATTCC TGAAAATATC TGCAACATTG TTACTGCCTA CATGGCTACA 
GGGGTTTCAC AGCAGACAAT GGACCTCCTT AATATCATCA GCCAGTTCCT TTTGTTCTTT 
AAGTCCTGTG TCACCCCAGT CCTCCTTTTC TGTCTCTGCA AACCCTTCAG TCGGGCCTTC 
ATGGAGTGCT GCTGCTGTTG CTGTGAGGAA TGCATTCAGA AGTCTTCAAC GGTGACCAGT 
GATGACAATG ACAACGAGTA CACCACGGAA CTCGAACTCT CGCCTTTCAG TACCATACGC 
CGTGAAATGT CCACTTTTGC TTCTGTCGGA ACTCATTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005293.1
CDS	1133..2974
Translation	MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPTVIQRRGRDAWGPGNSARDVLRARAPREEQGAAFLAGPSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLFYWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC

Target ORF information:

RefSeq Version	NM_005302.4
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005302.4

ORF Insert Sequence:

ATGCGAGCCC CGGGCGCGCT TCTCGCCCGC ATGTCGCGGC TACTGCTTCT GCTACTGCTC 
AAGGTGTCTG CCTCTTCTGC CCTCGGGGTC GCCCCTGCGT CCAGAAACGA AACTTGTCTG 
GGGGAGAGCT GTGCACCTAC AGTGATCCAG CGCCGCGGCA GGGACGCCTG GGGACCGGGA 
AATTCTGCAA GAGACGTTCT GCGAGCCCGA GCACCCAGGG AGGAGCAGGG GGCAGCGTTT 
CTTGCGGGAC CCTCCTGGGA CCTGCCGGCG GCCCCGGGCC GTGACCCGGC TGCAGGCAGA 
GGGGCGGAGG CGTCGGCAGC CGGACCCCCG GGACCTCCAA CCAGGCCACC TGGCCCCTGG 
AGGTGGAAAG GTGCTCGGGG TCAGGAGCCT TCTGAAACTT TGGGGAGAGG GAACCCCACG 
GCCCTCCAGC TCTTCCTTCA GATCTCAGAG GAGGAAGAGA AGGGTCCCAG AGGCGCTGGC 
ATTTCCGGGC GTAGCCAGGA GCAGAGTGTG AAGACAGTCC CCGGAGCCAG CGATCTTTTT 
TACTGGCCAA GGAGAGCCGG GAAACTCCAG GGTTCCCACC ACAAGCCCCT GTCCAAGACG 
GCCAATGGAC TGGCGGGGCA CGAAGGGTGG ACAATTGCAC TCCCGGGCCG GGCGCTGGCC 
CAGAATGGAT CCTTGGGTGA AGGAATCCAT GAGCCTGGGG GTCCCCGCCG GGGAAACAGC 
ACGAACCGGC GTGTGAGACT GAAGAACCCC TTCTACCCGC TGACCCAGGA GTCCTATGGA 
GCCTACGCGG TCATGTGTCT GTCCGTGGTG ATCTTCGGGA CCGGCATCAT TGGCAACCTG 
GCGGTGATGT GCATCGTGTG CCACAACTAC TACATGCGGA GCATCTCCAA CTCCCTCTTG 
GCCAACCTGG CCTTCTGGGA CTTTCTCATC ATCTTCTTCT GCCTTCCGCT GGTCATCTTC 
CACGAGCTGA CCAAGAAGTG GCTGCTGGAG GACTTCTCCT GCAAGATCGT GCCCTATATA 
GAGGTCGCTT CTCTGGGAGT CACCACTTTC ACCTTATGTG CTCTGTGCAT AGACCGCTTC 
CGTGCTGCCA CCAACGTACA GATGTACTAC GAAATGATCG AAAACTGTTC CTCAACAACT 
GCCAAACTTG CTGTTATATG GGTGGGAGCT CTATTGTTAG CACTTCCAGA AGTTGTTCTC 
CGCCAGCTGA GCAAGGAGGA TTTGGGGTTT AGTGGCCGAG CTCCGGCAGA AAGGTGCATT 
ATTAAGATCT CTCCTGATTT ACCAGACACC ATCTATGTTC TAGCCCTCAC CTACGACAGT 
GCGAGACTGT GGTGGTATTT TGGCTGTTAC TTTTGTTTGC CCACGCTTTT CACCATCACC 
TGCTCTCTAG TGACTGCGAG GAAAATCCGC AAAGCAGAGA AAGCCTGTAC CCGAGGGAAT 
AAACGGCAGA TTCAACTAGA GAGTCAGATG AACTGTACAG TAGTGGCACT GACCATTTTA 
TATGGATTTT GCATTATTCC TGAAAATATC TGCAACATTG TTACTGCCTA CATGGCTACA 
GGGGTTTCAC AGCAGACAAT GGACCTCCTT AATATCATCA GCCAGTTCCT TTTGTTCTTT 
AAGTCCTGTG TCACCCCAGT CCTCCTTTTC TGTCTCTGCA AACCCTTCAG TCGGGCCTTC 
ATGGAGTGCT GCTGCTGTTG CTGTGAGGAA TGCATTCAGA AGTCTTCAAC GGTGACCAGT 
GATGACAATG ACAACGAGTA CACCACGGAA CTCGAACTCT CGCCTTTCAG TACCATACGC 
CGTGAAATGT CCACTTTTGC TTCTGTCGGA ACTCATTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPR37 ( NM_005302.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_005293.1 Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.

Price & Availability↑

CloneID	OHu14150
Clone ID Related Accession (Same CDS sequence)	NM_005302.4 , NM_005302.5 , NM_005302.3
Accession Version	NM_005302.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-05
Organism	Homo sapiens(Human)
Product	prosaposin receptor GPR37 precursor
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB475687.1, BC040007.1, AF017262.1, DB517451.1 and DB495592.1. On Oct 16, 2012 this sequence version replaced NM_005302.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.12057.1, SRR1660805.155743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGAGCCC CGGGCGCGCT TCTCGCCCGC ATGTCGCGGC TACTGCTTCT GCTACTGCTC 
AAGGTGTCTG CCTCTTCTGC CCTCGGGGTC GCCCCTGCGT CCAGAAACGA AACTTGTCTG 
GGGGAGAGCT GTGCACCTAC AGTGATCCAG CGCCGCGGCA GGGACGCCTG GGGACCGGGA 
AATTCTGCAA GAGACGTTCT GCGAGCCCGA GCACCCAGGG AGGAGCAGGG GGCAGCGTTT 
CTTGCGGGAC CCTCCTGGGA CCTGCCGGCG GCCCCGGGCC GTGACCCGGC TGCAGGCAGA 
GGGGCGGAGG CGTCGGCAGC CGGACCCCCG GGACCTCCAA CCAGGCCACC TGGCCCCTGG 
AGGTGGAAAG GTGCTCGGGG TCAGGAGCCT TCTGAAACTT TGGGGAGAGG GAACCCCACG 
GCCCTCCAGC TCTTCCTTCA GATCTCAGAG GAGGAAGAGA AGGGTCCCAG AGGCGCTGGC 
ATTTCCGGGC GTAGCCAGGA GCAGAGTGTG AAGACAGTCC CCGGAGCCAG CGATCTTTTT 
TACTGGCCAA GGAGAGCCGG GAAACTCCAG GGTTCCCACC ACAAGCCCCT GTCCAAGACG 
GCCAATGGAC TGGCGGGGCA CGAAGGGTGG ACAATTGCAC TCCCGGGCCG GGCGCTGGCC 
CAGAATGGAT CCTTGGGTGA AGGAATCCAT GAGCCTGGGG GTCCCCGCCG GGGAAACAGC 
ACGAACCGGC GTGTGAGACT GAAGAACCCC TTCTACCCGC TGACCCAGGA GTCCTATGGA 
GCCTACGCGG TCATGTGTCT GTCCGTGGTG ATCTTCGGGA CCGGCATCAT TGGCAACCTG 
GCGGTGATGT GCATCGTGTG CCACAACTAC TACATGCGGA GCATCTCCAA CTCCCTCTTG 
GCCAACCTGG CCTTCTGGGA CTTTCTCATC ATCTTCTTCT GCCTTCCGCT GGTCATCTTC 
CACGAGCTGA CCAAGAAGTG GCTGCTGGAG GACTTCTCCT GCAAGATCGT GCCCTATATA 
GAGGTCGCTT CTCTGGGAGT CACCACTTTC ACCTTATGTG CTCTGTGCAT AGACCGCTTC 
CGTGCTGCCA CCAACGTACA GATGTACTAC GAAATGATCG AAAACTGTTC CTCAACAACT 
GCCAAACTTG CTGTTATATG GGTGGGAGCT CTATTGTTAG CACTTCCAGA AGTTGTTCTC 
CGCCAGCTGA GCAAGGAGGA TTTGGGGTTT AGTGGCCGAG CTCCGGCAGA AAGGTGCATT 
ATTAAGATCT CTCCTGATTT ACCAGACACC ATCTATGTTC TAGCCCTCAC CTACGACAGT 
GCGAGACTGT GGTGGTATTT TGGCTGTTAC TTTTGTTTGC CCACGCTTTT CACCATCACC 
TGCTCTCTAG TGACTGCGAG GAAAATCCGC AAAGCAGAGA AAGCCTGTAC CCGAGGGAAT 
AAACGGCAGA TTCAACTAGA GAGTCAGATG AACTGTACAG TAGTGGCACT GACCATTTTA 
TATGGATTTT GCATTATTCC TGAAAATATC TGCAACATTG TTACTGCCTA CATGGCTACA 
GGGGTTTCAC AGCAGACAAT GGACCTCCTT AATATCATCA GCCAGTTCCT TTTGTTCTTT 
AAGTCCTGTG TCACCCCAGT CCTCCTTTTC TGTCTCTGCA AACCCTTCAG TCGGGCCTTC 
ATGGAGTGCT GCTGCTGTTG CTGTGAGGAA TGCATTCAGA AGTCTTCAAC GGTGACCAGT 
GATGACAATG ACAACGAGTA CACCACGGAA CTCGAACTCT CGCCTTTCAG TACCATACGC 
CGTGAAATGT CCACTTTTGC TTCTGTCGGA ACTCATTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005293.1
CDS	1050..2891
Translation	MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPTVIQRRGRDAWGPGNSARDVLRARAPREEQGAAFLAGPSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLFYWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC

Target ORF information:

RefSeq Version	NM_005302.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens G protein-coupled receptor 37 (GPR37), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005302.3

ORF Insert Sequence:

ATGCGAGCCC CGGGCGCGCT TCTCGCCCGC ATGTCGCGGC TACTGCTTCT GCTACTGCTC 
AAGGTGTCTG CCTCTTCTGC CCTCGGGGTC GCCCCTGCGT CCAGAAACGA AACTTGTCTG 
GGGGAGAGCT GTGCACCTAC AGTGATCCAG CGCCGCGGCA GGGACGCCTG GGGACCGGGA 
AATTCTGCAA GAGACGTTCT GCGAGCCCGA GCACCCAGGG AGGAGCAGGG GGCAGCGTTT 
CTTGCGGGAC CCTCCTGGGA CCTGCCGGCG GCCCCGGGCC GTGACCCGGC TGCAGGCAGA 
GGGGCGGAGG CGTCGGCAGC CGGACCCCCG GGACCTCCAA CCAGGCCACC TGGCCCCTGG 
AGGTGGAAAG GTGCTCGGGG TCAGGAGCCT TCTGAAACTT TGGGGAGAGG GAACCCCACG 
GCCCTCCAGC TCTTCCTTCA GATCTCAGAG GAGGAAGAGA AGGGTCCCAG AGGCGCTGGC 
ATTTCCGGGC GTAGCCAGGA GCAGAGTGTG AAGACAGTCC CCGGAGCCAG CGATCTTTTT 
TACTGGCCAA GGAGAGCCGG GAAACTCCAG GGTTCCCACC ACAAGCCCCT GTCCAAGACG 
GCCAATGGAC TGGCGGGGCA CGAAGGGTGG ACAATTGCAC TCCCGGGCCG GGCGCTGGCC 
CAGAATGGAT CCTTGGGTGA AGGAATCCAT GAGCCTGGGG GTCCCCGCCG GGGAAACAGC 
ACGAACCGGC GTGTGAGACT GAAGAACCCC TTCTACCCGC TGACCCAGGA GTCCTATGGA 
GCCTACGCGG TCATGTGTCT GTCCGTGGTG ATCTTCGGGA CCGGCATCAT TGGCAACCTG 
GCGGTGATGT GCATCGTGTG CCACAACTAC TACATGCGGA GCATCTCCAA CTCCCTCTTG 
GCCAACCTGG CCTTCTGGGA CTTTCTCATC ATCTTCTTCT GCCTTCCGCT GGTCATCTTC 
CACGAGCTGA CCAAGAAGTG GCTGCTGGAG GACTTCTCCT GCAAGATCGT GCCCTATATA 
GAGGTCGCTT CTCTGGGAGT CACCACTTTC ACCTTATGTG CTCTGTGCAT AGACCGCTTC 
CGTGCTGCCA CCAACGTACA GATGTACTAC GAAATGATCG AAAACTGTTC CTCAACAACT 
GCCAAACTTG CTGTTATATG GGTGGGAGCT CTATTGTTAG CACTTCCAGA AGTTGTTCTC 
CGCCAGCTGA GCAAGGAGGA TTTGGGGTTT AGTGGCCGAG CTCCGGCAGA AAGGTGCATT 
ATTAAGATCT CTCCTGATTT ACCAGACACC ATCTATGTTC TAGCCCTCAC CTACGACAGT 
GCGAGACTGT GGTGGTATTT TGGCTGTTAC TTTTGTTTGC CCACGCTTTT CACCATCACC 
TGCTCTCTAG TGACTGCGAG GAAAATCCGC AAAGCAGAGA AAGCCTGTAC CCGAGGGAAT 
AAACGGCAGA TTCAACTAGA GAGTCAGATG AACTGTACAG TAGTGGCACT GACCATTTTA 
TATGGATTTT GCATTATTCC TGAAAATATC TGCAACATTG TTACTGCCTA CATGGCTACA 
GGGGTTTCAC AGCAGACAAT GGACCTCCTT AATATCATCA GCCAGTTCCT TTTGTTCTTT 
AAGTCCTGTG TCACCCCAGT CCTCCTTTTC TGTCTCTGCA AACCCTTCAG TCGGGCCTTC 
ATGGAGTGCT GCTGCTGTTG CTGTGAGGAA TGCATTCAGA AGTCTTCAAC GGTGACCAGT 
GATGACAATG ACAACGAGTA CACCACGGAA CTCGAACTCT CGCCTTTCAG TACCATACGC 
CGTGAAATGT CCACTTTTGC TTCTGTCGGA ACTCATTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.
EMBO reports18(5)712-725(2017 May)
Berger BS,Acebron SP,Herbst J,Koch S,Niehrs C

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.
Molecular systems biology13(3)918(2017 03)
Sokolina K,Kittanakom S,Snider J,Kotlyar M,Maurice P,Gand?a J,Benleulmi-Chaachoua A,Tadagaki K,Oishi A,Wong V,Malty RH,Deineko V,Aoki H,Amin S,Yao Z,Morat? X,Otasek D,Kobayashi H,Menendez J,Auerbach D,Angers S,Pr?ulj N,Bouvier M,Babu M,Ciruela F,Jockers R,Jurisica I,Stagljar I

REG4 promotes peritoneal metastasis of gastric cancer through GPR37.
Oncotarget7(19)27874-88(2016 May)
Wang H,Hu L,Zang M,Zhang B,Duan Y,Fan Z,Li J,Su L,Yan M,Zhu Z,Liu B,Yang Q

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GPR37 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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