GPR32 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPR32
Entrez Gene ID	2854
Full Name	G protein-coupled receptor 32
Synonyms	RVDR1
General protein information	Preferred Names G protein-coupled receptor 32 Names probable G-protein coupled receptor 32 resolvin D1 receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.33
Summary	This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. The encoded protein binds to resolvin D1 and lipoxin A4 and has been linked to pulmonary inflammation. A related pseudogene has been identified on chromosome 19. [provided by RefSeq, Nov 2012].
Disorder MIM:	603195

mRNA and Protein(s)

mRNA	Protein	Name
NM_001506.2	NP_001497.1	probable G-protein coupled receptor 32

Pathways from BioSystems

Homologies

Bos taurus (cattle)	GPR32	XP_003587352.1
Homo sapiens (human)	GPR32	NP_001497.1
Pan troglodytes (chimpanzee)	GPR32	XP_001173894.1

Gene Ontology
Bibliography

Related articles in PubMed

ResolvinD
Zheng S, Wang Q, D'Souza V, Bartis D, Dancer R, Parekh D, Gao F, Lian Q, Jin S, Thickett DR
Laboratory investigation; a journal of technical methods and pathology98(1)130-140(2018 Jan)

S1000A12, Chitotriosidase, and Resolvin D1 as Potential Biomarkers of Familial Mediterranean Fever.
Taylan A, Gurler O, Toprak B, Sisman AR, Yalcin H, Colak A, Sari I
Journal of Korean medical science30(9)1241-5(2015 Sep)

Effect of diclofenac on the levels of lipoxin A4 and Resolvin D1 and E1 in the post-ERCP pancreatitis.
Zhao XW, Bao JJ, Hu C, Ding H, Liu XC, Mei Q, Xu JM
Digestive diseases and sciences59(12)2992-6(2014 Dec)

Resolvin D1 attenuates polyinosinic-polycytidylic acid-induced inflammatory signaling in human airway epithelial cells via TAK1.
Hsiao HM, Thatcher TH, Levy EP, Fulton RA, Owens KM, Phipps RP, Sime PJ
Journal of immunology (Baltimore, Md. : 1950)193(10)4980-7(2014 Nov)

Resolvin D1 inhibits TGF-?1-induced epithelial mesenchymal transition of A549 lung cancer cells via lipoxin A4 receptor/formyl peptide receptor 2 and GPR32.
Lee HJ, Park MK, Lee EJ, Lee CH
The international journal of biochemistry & cell biology45(12)2801-7(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our findings indicate that chitotriosidase and S10012A are useful in diagnosis and detection of subclinical inflammation and/or assessment of disease activity in FMF patients.
Title: S1000A12, Chitotriosidase, and Resolvin D1 as Potential Biomarkers of Familial Mediterranean Fever.

The effects of diclofenac on the incidence of pancreatitis following endoscopic retrograde cholangiopancreatography via lipoxin A4 and resolvin D1 and E1 levels is reported.
Title: Effect of diclofenac on the levels of lipoxin A4 and Resolvin D1 and E1 in the post-ERCP pancreatitis.

Resolvin D1 attenuates the viral mimic-induced inflammatory signaling in human airway epithelial cells via TAK1.
Title: Resolvin D1 attenuates polyinosinic-polycytidylic acid-induced inflammatory signaling in human airway epithelial cells via TAK1.

Results suggest that resolvin D1 inhibited TGF-beta1-induced EMT via ALX/FPR2 and GPR32 by reducing the expression of ZEB1.
Title: Resolvin D1 inhibits TGF-?1-induced epithelial mesenchymal transition of A549 lung cancer cells via lipoxin A4 receptor/formyl peptide receptor 2 and GPR32.

results indicate that RvD1 specifically interacts with both ALX and GPR32 on phagocytes.
Title: Resolvin D1 binds human phagocytes with evidence for proresolving receptors.

The following GPR32 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPR32 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu08663	NM_001506.2 Latest version!	Homo sapiens G protein-coupled receptor 32 (GPR32), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$149.50-$209.30 $299.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPR32 ( NM_001506.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001497.1 Homo sapiens G protein-coupled receptor 32 (GPR32), mRNA.

Price & Availability↑

CloneID	OHu08663
Clone ID Related Accession (Same CDS sequence)	NM_001506.2
Accession Version	NM_001506.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	probable G-protein coupled receptor 32
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC095544.1 and AC010325.7. On Dec 1, 2012 this sequence version replaced NM_001506.1. ##Evidence-Data-START## Transcript is intronless :: BC095544.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000270590.4/ ENSP00000270590.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAATGGGG TCTCGGAGGG GACCAGAGGC TGCAGTGACA GGCAACCTGG GGTCCTGACA 
CGTGATCGCT CTTGTTCCAG GAAGATGAAC TCTTCCGGAT GCCTGTCTGA GGAGGTGGGG 
TCCCTCCGCC CACTGACTGT GGTTATCCTG TCTGCGTCCA TTGTCGTCGG AGTGCTGGGC 
AATGGGCTGG TGCTGTGGAT GACTGTCTTC CGTATGGCAC GCACGGTCTC CACCGTCTGC 
TTCTTCCACC TGGCCCTTGC CGATTTCATG CTCTCACTGT CTCTGCCCAT TGCCATGTAC 
TATATTGTCT CCAGGCAGTG GCTCCTCGGA GAGTGGGCCT GCAAACTCTA CATCACCTTT 
GTGTTCCTCA GCTACTTTGC CAGTAACTGC CTCCTTGTCT TCATCTCTGT GGACCGTTGC 
ATCTCTGTCC TCTACCCCGT CTGGGCCCTG AACCACCGCA CTGTGCAGCG GGCGAGCTGG 
CTGGCCTTTG GGGTGTGGCT CCTGGCCGCC GCCTTGTGCT CTGCGCACCT GAAATTCCGG 
ACAACCAGAA AATGGAATGG CTGTACGCAC TGCTACTTGG CGTTCAACTC TGACAATGAG 
ACTGCCCAGA TTTGGATTGA AGGGGTCGTG GAGGGACACA TTATAGGGAC CATTGGCCAC 
TTCCTGCTGG GCTTCCTGGG GCCCTTAGCA ATCATAGGCA CCTGCGCCCA CCTCATCCGG 
GCCAAGCTCT TGCGGGAGGG CTGGGTCCAT GCCAACCGGC CCAAGAGGCT GCTGCTGGTG 
CTGGTGAGCG CTTTCTTTAT CTTCTGGTCC CCGTTTAACG TGGTGCTGTT GGTCCATCTG 
TGGCGACGGG TGATGCTCAA GGAAATCTAC CACCCCCGGA TGCTGCTCAT CCTCCAGGCT 
AGCTTTGCCT TGGGCTGTGT CAACAGCAGC CTCAACCCCT TCCTCTACGT CTTCGTTGGC 
AGAGATTTCC AAGAAAAGTT TTTCCAGTCT TTGACTTCTG CCCTGGCGAG GGCGTTTGGA 
GAGGAGGAGT TTCTGTCATC CTGTCCCCGT GGCAACGCCC CCCGGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001497.1
CDS	138..1208
Translation	MNGVSEGTRGCSDRQPGVLTRDRSCSRKMNSSGCLSEEVGSLRPLTVVILSASIVVGVLGNGLVLWMTVFRMARTVSTVCFFHLALADFMLSLSLPIAMYYIVSRQWLLGEWACKLYITFVFLSYFASNCLLVFISVDRCISVLYPVWALNHRTVQRASWLAFGVWLLAAALCSAHLKFRTTRKWNGCTHCYLAFNSDNETAQIWIEGVVEGHIIGTIGHFLLGFLGPLAIIGTCAHLIRAKLLREGWVHANRPKRLLLVLVSAFFIFWSPFNVVLLVHLWRRVMLKEIYHPRMLLILQASFALGCVNSSLNPFLYVFVGRDFQEKFFQSLTSALARAFGEEEFLSSCPRGNAPRE

Target ORF information:

RefSeq Version	NM_001506.2
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein-coupled receptor 32 (GPR32), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001506.2

ORF Insert Sequence:

ATGAATGGGG TCTCGGAGGG GACCAGAGGC TGCAGTGACA GGCAACCTGG GGTCCTGACA 
CGTGATCGCT CTTGTTCCAG GAAGATGAAC TCTTCCGGAT GCCTGTCTGA GGAGGTGGGG 
TCCCTCCGCC CACTGACTGT GGTTATCCTG TCTGCGTCCA TTGTCGTCGG AGTGCTGGGC 
AATGGGCTGG TGCTGTGGAT GACTGTCTTC CGTATGGCAC GCACGGTCTC CACCGTCTGC 
TTCTTCCACC TGGCCCTTGC CGATTTCATG CTCTCACTGT CTCTGCCCAT TGCCATGTAC 
TATATTGTCT CCAGGCAGTG GCTCCTCGGA GAGTGGGCCT GCAAACTCTA CATCACCTTT 
GTGTTCCTCA GCTACTTTGC CAGTAACTGC CTCCTTGTCT TCATCTCTGT GGACCGTTGC 
ATCTCTGTCC TCTACCCCGT CTGGGCCCTG AACCACCGCA CTGTGCAGCG GGCGAGCTGG 
CTGGCCTTTG GGGTGTGGCT CCTGGCCGCC GCCTTGTGCT CTGCGCACCT GAAATTCCGG 
ACAACCAGAA AATGGAATGG CTGTACGCAC TGCTACTTGG CGTTCAACTC TGACAATGAG 
ACTGCCCAGA TTTGGATTGA AGGGGTCGTG GAGGGACACA TTATAGGGAC CATTGGCCAC 
TTCCTGCTGG GCTTCCTGGG GCCCTTAGCA ATCATAGGCA CCTGCGCCCA CCTCATCCGG 
GCCAAGCTCT TGCGGGAGGG CTGGGTCCAT GCCAACCGGC CCAAGAGGCT GCTGCTGGTG 
CTGGTGAGCG CTTTCTTTAT CTTCTGGTCC CCGTTTAACG TGGTGCTGTT GGTCCATCTG 
TGGCGACGGG TGATGCTCAA GGAAATCTAC CACCCCCGGA TGCTGCTCAT CCTCCAGGCT 
AGCTTTGCCT TGGGCTGTGT CAACAGCAGC CTCAACCCCT TCCTCTACGT CTTCGTTGGC 
AGAGATTTCC AAGAAAAGTT TTTCCAGTCT TTGACTTCTG CCCTGGCGAG GGCGTTTGGA 
GAGGAGGAGT TTCTGTCATC CTGTCCCCGT GGCAACGCCC CCCGGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ResolvinD
Laboratory investigation; a journal of technical methods and pathology98(1)130-140(2018 Jan)
Zheng S,Wang Q,D'Souza V,Bartis D,Dancer R,Parekh D,Gao F,Lian Q,Jin S,Thickett DR

S1000A12, Chitotriosidase, and Resolvin D1 as Potential Biomarkers of Familial Mediterranean Fever.
Journal of Korean medical science30(9)1241-5(2015 Sep)
Taylan A,Gurler O,Toprak B,Sisman AR,Yalcin H,Colak A,Sari I

Effect of diclofenac on the levels of lipoxin A4 and Resolvin D1 and E1 in the post-ERCP pancreatitis.
Digestive diseases and sciences59(12)2992-6(2014 Dec)
Zhao XW,Bao JJ,Hu C,Ding H,Liu XC,Mei Q,Xu JM

Resolvin D1 attenuates polyinosinic-polycytidylic acid-induced inflammatory signaling in human airway epithelial cells via TAK1.
Journal of immunology (Baltimore, Md. : 1950)193(10)4980-7(2014 Nov)
Hsiao HM,Thatcher TH,Levy EP,Fulton RA,Owens KM,Phipps RP,Sime PJ

Resolvin D1 inhibits TGF-?1-induced epithelial mesenchymal transition of A549 lung cancer cells via lipoxin A4 receptor/formyl peptide receptor 2 and GPR32.
The international journal of biochemistry & cell biology45(12)2801-7(2013 Dec)
Lee HJ,Park MK,Lee EJ,Lee CH

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

GPR32 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報