Gene Symbol | CHAMP1 |
Entrez Gene ID | 283489 |
Full Name | chromosome alignment maintaining phosphoprotein 1 |
Synonyms | C13orf8,CAMP,CHAMP,MRD40,ZNF828 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(Human) |
Genome | |
Summary | This gene encodes a zinc finger protein that functions as a regulator of chromosome segregation in mitosis. The encoded protein is required for correct alignment of chromosomes on the metaphase plate, and plays a role in maintaining the attachment of sister kinetochores to microtubules from opposite spindle poles. Mutations in this gene are associated with an autosomal dominant form of intellectual disability. [provided by RefSeq, Jul 2017]. |
Disorder MIM: | |
Disorder Html: | Mental retardation, autosomal dominant 40, 616579 (3) |