OR8B4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR8B4
Entrez Gene ID	283162
Full Name	olfactory receptor family 8 subfamily B member 4 (gene/pseudogene)
Synonyms	OR11-315,OR8B4P
General protein information	Preferred Names olfactory receptor family 8 subfamily B member 4 (gene/pseudogene) Names olfactory receptor 8B4 olfactory receptor OR11-315 olfactory receptor, family 8, subfamily B, member 4 pseudogene
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q24.2
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001005196.1	NP_001005196.1	olfactory receptor 8B4

Pathways from BioSystems

Homologies

	OR8B4	XP_001106013.2
Canis lupus familiaris (dog)	OR8B4	XP_546436.3
Mus musculus (house mouse)	Olfr878	NP_667009.1
Bos taurus (cattle)	OR8B4	XP_002699238.2
Rattus norvegicus (Norway rat)	Olr1202	NP_001000817.1
Homo sapiens (human)	OR8B4	NP_001005196.1

Gene Ontology
Bibliography

Related articles in PubMed

Personal receptor repertoires: olfaction as a model.
Olender T, Waszak SM, Viavant M, Khen M, Ben-Asher E, Reyes A, Nativ N, Wysocki CJ, Ge D, Lancet D
BMC genomics13414(2012 Aug)

A probabilistic classifier for olfactory receptor pseudogenes.
Menashe I, Aloni R, Lancet D
BMC bioinformatics7393(2006 Aug)

The human olfactory receptor gene family.
Malnic B, Godfrey PA, Buck LB
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)

DEFOG: a practical scheme for deciphering families of genes.
Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R
Genomics80(3)295-302(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following OR8B4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR8B4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29617	NM_001005196.1 Latest version!	Homo sapiens olfactory receptor family 8 subfamily B member 4 (gene/pseudogene) (OR8B4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR8B4 ( NM_001005196.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001005196.1 Homo sapiens olfactory receptor family 8 subfamily B member 4 (gene/pseudogene) (OR8B4), mRNA.

Price & Availability↑

CloneID	OHu29617
Clone ID Related Accession (Same CDS sequence)	NM_001005196.1
Accession Version	NM_001005196.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	olfactory receptor 8B4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB065831.1. On Sep 22, 2004 this sequence version replaced XM_210186.2. Sequence Note: This gene is a segregating pseudogene. This RefSeq represents the protein encoded by the reference genome allele, which is predicted to be functional according to the Classifier for Olfactory Receptor Pseudogenes. CCDS Note: This olfactory receptor gene is a segregating pseudogene (PMID:22908908), where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele that is predicted to be non-functional. This CCDS is being retained because the Classifier for Olfactory Receptor Pseudogenes (CORP) predicts the reference genome allele to be functional. ##Evidence-Data-START## Transcript is intronless :: BC136865.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22908908 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGACTCTGA GAAACAGCTC CTCAGTGACT GAGTTTATCC TTGTGGGATT ATCAGAACAG 
CCAGAGCTCC AGCTCCCTCT TTTCCTTCTA TTCTTAGGGA TCTATGTGTT CACTGTGGTG 
GGCAACTTGG GCTTGATCAC CTTAATTGGG ATAAATCCTA GCCTTCACAC CCCCATGTAC 
TTTTTCCTCT TCAACTTGTC CTTTATAGAT CTCTGTTATT CCTGTGTGTT TACCCCCAAA 
ATGCTGAATG ACTTTGTTTC AGAAAGTATC ATCTCTTATG TGGGATGTAT GACTCAGCTA 
TTTTTCTTCT GTTTCTTTGT CAATTCTGAG TGCTATGTGT TGGTATCAAT GGCCTATGAT 
CGCTATGTGG CCATCTGCAA CCCCCTGCTC TACATGGTCA CCATGTCCCC AAGGGTCTGC 
TTTCTGCTGA TGTTTGGTTC CTATGTGGTA GGGTTTGCTG GGGCCATGGC CCACACTGGA 
AGCATGCTGC GACTGACCTT CTGTGATTCC AACGTCATTG ACCATTATCT GTGTGACGTT 
CTCCCCCTCT TGCAGCTCTC CTGCACCAGC ACCCATGTCA GTGAGCTGGT ATTTTTCATT 
GTTGTTGGAG TAATCACCAT GCTATCCAGC ATAAGCATCG TCATCTCTTA CGCTTTGATA 
CTCTCCAACA TCCTCTGTAT TCCTTCTGCA GAGGGCAGAT CCAAAGCCTT TAGCACATGG 
GGCTCCCACA TAATTGCTGT TGCTCTGTTT TTTGGGTCAG GGACATTCAC CTACTTAACA 
ACATCTTTTC CTGGCTCTAT GAACCATGGC AGATTTGCCT CAGTCTTTTA CACCAATGTG 
GTTCCCATGC TTAACCCTTC GATCTACAGT TTGAGGAATA AGGATGATAA ACTTGCCCTG 
GGCAAAACCC TGAAGAGAGT GCTCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005196.1
CDS	1..930
Translation	MTLRNSSSVTEFILVGLSEQPELQLPLFLLFLGIYVFTVVGNLGLITLIGINPSLHTPMYFFLFNLSFIDLCYSCVFTPKMLNDFVSESIISYVGCMTQLFFFCFFVNSECYVLVSMAYDRYVAICNPLLYMVTMSPRVCFLLMFGSYVVGFAGAMAHTGSMLRLTFCDSNVIDHYLCDVLPLLQLSCTSTHVSELVFFIVVGVITMLSSISIVISYALILSNILCIPSAEGRSKAFSTWGSHIIAVALFFGSGTFTYLTTSFPGSMNHGRFASVFYTNVVPMLNPSIYSLRNKDDKLALGKTLKRVLF

Target ORF information:

RefSeq Version	NM_001005196.1
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 8 subfamily B member 4 (gene/pseudogene) (OR8B4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005196.1

ORF Insert Sequence:

ATGACTCTGA GAAACAGCTC CTCAGTGACT GAGTTTATCC TTGTGGGATT ATCAGAACAG 
CCAGAGCTCC AGCTCCCTCT TTTCCTTCTA TTCTTAGGGA TCTATGTGTT CACTGTGGTG 
GGCAACTTGG GCTTGATCAC CTTAATTGGG ATAAATCCTA GCCTTCACAC CCCCATGTAC 
TTTTTCCTCT TCAACTTGTC CTTTATAGAT CTCTGTTATT CCTGTGTGTT TACCCCCAAA 
ATGCTGAATG ACTTTGTTTC AGAAAGTATC ATCTCTTATG TGGGATGTAT GACTCAGCTA 
TTTTTCTTCT GTTTCTTTGT CAATTCTGAG TGCTATGTGT TGGTATCAAT GGCCTATGAT 
CGCTATGTGG CCATCTGCAA CCCCCTGCTC TACATGGTCA CCATGTCCCC AAGGGTCTGC 
TTTCTGCTGA TGTTTGGTTC CTATGTGGTA GGGTTTGCTG GGGCCATGGC CCACACTGGA 
AGCATGCTGC GACTGACCTT CTGTGATTCC AACGTCATTG ACCATTATCT GTGTGACGTT 
CTCCCCCTCT TGCAGCTCTC CTGCACCAGC ACCCATGTCA GTGAGCTGGT ATTTTTCATT 
GTTGTTGGAG TAATCACCAT GCTATCCAGC ATAAGCATCG TCATCTCTTA CGCTTTGATA 
CTCTCCAACA TCCTCTGTAT TCCTTCTGCA GAGGGCAGAT CCAAAGCCTT TAGCACATGG 
GGCTCCCACA TAATTGCTGT TGCTCTGTTT TTTGGGTCAG GGACATTCAC CTACTTAACA 
ACATCTTTTC CTGGCTCTAT GAACCATGGC AGATTTGCCT CAGTCTTTTA CACCAATGTG 
GTTCCCATGC TTAACCCTTC GATCTACAGT TTGAGGAATA AGGATGATAA ACTTGCCCTG 
GGCAAAACCC TGAAGAGAGT GCTCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Personal receptor repertoires: olfaction as a model.
BMC genomics13414(2012 Aug)
Olender T,Waszak SM,Viavant M,Khen M,Ben-Asher E,Reyes A,Nativ N,Wysocki CJ,Ge D,Lancet D

A probabilistic classifier for olfactory receptor pseudogenes.
BMC bioinformatics7393(2006 Aug)
Menashe I,Aloni R,Lancet D

The human olfactory receptor gene family.
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)
Malnic B,Godfrey PA,Buck LB

DEFOG: a practical scheme for deciphering families of genes.
Genomics80(3)295-302(2002 Sep)
Fuchs T,Malecova B,Linhart C,Sharan R,Khen M,Herwig R,Shmulevich D,Elkon R,Steinfath M,O'Brien JK,Radelof U,Lehrach H,Lancet D,Shamir R

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OR8B4 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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