Gene Symbol | GNRH1 |
Entrez Gene ID | 2796 |
Full Name | gonadotropin releasing hormone 1 |
Synonyms | GNRH,GRH,LHRH,LNRH |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]. |
Disorder MIM: | |
Disorder Html: | ?Hypogonadotropic hypogonadism 12 with or without anosmia, 614841 (3) |