GLP1R cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GLP1R
Entrez Gene ID	2740
Full Name	glucagon like peptide 1 receptor
Synonyms	GLP-1,GLP-1-R,GLP-1R
General protein information	Preferred Names glucagon like peptide 1 receptor Names glucagon-like peptide 1 receptor GLP-1 receptor GLP1 receptor seven transmembrane helix receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.2
Summary	This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016].
Disorder MIM:	138032

mRNA and Protein(s)

mRNA	Protein	Name
NM_002062.3	NP_002053.3	glucagon-like peptide 1 receptor precursor
XM_017010750.1	XP_016866239.1	glucagon-like peptide 1 receptor isoform X1
NM_002062.4	NP_002053.3	glucagon-like peptide 1 receptor precursor
XM_017010751.1	XP_016866240.1	glucagon-like peptide 1 receptor isoform X2
NM_002062.5	NP_002053.3	glucagon-like peptide 1 receptor precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	GLP1R	NP_001129023.1
Pan troglodytes (chimpanzee)	GLP1R	XP_527380.2
Canis lupus familiaris (dog)	GLP1R	XP_005627815.1
Homo sapiens (human)	GLP1R	NP_002053.3
Bos taurus (cattle)	GLP1R	XP_002697273.2
Mus musculus (house mouse)	Glp1r	NP_067307.2
Rattus norvegicus (Norway rat)	Glp1r	NP_036860.1
Xenopus tropicalis (tropical clawed frog)	glp1r	XP_004919894.1

Gene Ontology
Bibliography

Related articles in PubMed

Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-?B Activation.
Iwaya C, Nomiyama T, Komatsu S, Kawanami T, Tsutsumi Y, Hamaguchi Y, Horikawa T, Yoshinaga Y, Yamashita S, Tanaka T, Terawaki Y, Tanabe M, Nabeshima K, Iwasaki A, Yanase T
Endocrinology158(12)4218-4232(2017 Dec)

Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor.
Cai Y, Liu Y, Culhane KJ, DeVree BT, Yang Y, Sunahara RK, Yan ECY
PloS one12(6)e0179568(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that exendin-4 (Ex-4) could attenuate breast cancer cell proliferation via activation of glucagonlike peptide-1 (GLP-1) receptor (GLP-1R) and subsequent inhibition of nuclear factor kappaB (NF-kappaB ) activation.
Title: Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-?B Activation.

crystal structures of the human GLP-1R transmembrane domain in complex with two different negative allosteric modulators, PF-06372222 and NNC0640, at 2.7 and 3.0 A resolution, respectively
Title: Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.

crystal structure of the full-length GLP-1 receptor bound to a truncated peptide agonist
Title: Crystal structure of the GLP-1 receptor bound to a peptide agonist.

analysis of the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor
Title: Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R).

Data show that purified glucagon-like peptide-1 (GLP-1) receptor (GLP1R)GLP1R in nanodiscs that could bind to GLP-1 and exendin-4 and activate Gs protein.
Title: Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor.

The following GLP1R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GLP1R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26898	NM_002062.5 Latest version!	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu96544	XM_017010750.1 Latest version!	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu96545	XM_017010751.1 Latest version!	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu26898	NM_002062.3	Homo sapiens glucagon-like peptide 1 receptor (GLP1R), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu26898	NM_002062.4	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GLP1R ( NM_002062.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002053.3 Homo sapiens glucagon-like peptide 1 receptor (GLP1R), mRNA.

Price & Availability↑

CloneID	OHu26898
Clone ID Related Accession (Same CDS sequence)	NM_002062.3 , NM_002062.4 , NM_002062.5
Accession Version	NM_002062.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	glucagon-like peptide 1 receptor precursor
Comment

ATGGCCGGCG CCCCCGGCCC GCTGCGCCTT GCGCTGCTGC TGCTCGGGAT GGTGGGCAGG 
GCCGGCCCCC GCCCCCAGGG TGCCACTGTG TCCCTCTGGG AGACGGTGCA GAAATGGCGA 
GAATACCGAC GCCAGTGCCA GCGCTCCCTG ACTGAGGATC CACCTCCTGC CACAGACTTG 
TTCTGCAACC GGACCTTCGA TGAATACGCC TGCTGGCCAG ATGGGGAGCC AGGCTCGTTC 
GTGAATGTCA GCTGCCCCTG GTACCTGCCC TGGGCCAGCA GTGTGCCGCA GGGCCACGTG 
TACCGGTTCT GCACAGCTGA AGGCCTCTGG CTGCAGAAGG ACAACTCCAG CCTGCCCTGG 
AGGGACTTGT CGGAGTGCGA GGAGTCCAAG CGAGGGGAAA GAAGCTCCCC GGAGGAGCAG 
CTCCTGTTCC TCTACATCAT CTACACGGTG GGCTACGCAC TCTCCTTCTC TGCTCTGGTT 
ATCGCCTCTG CGATCCTCCT CGGCTTCAGA CACCTGCACT GCACCAGGAA CTACATCCAC 
CTGAACCTGT TTGCATCCTT CATCCTGCGA GCATTGTCCG TCTTCATCAA GGACGCAGCC 
CTGAAGTGGA TGTATAGCAC AGCCGCCCAG CAGCACCAGT GGGATGGGCT CCTCTCCTAC 
CAGGACTCTC TGAGCTGCCG CCTGGTGTTT CTGCTCATGC AGTACTGTGT GGCGGCCAAT 
TACTACTGGC TCTTGGTGGA GGGCGTGTAC CTGTACACAC TGCTGGCCTT CTCGGTCTTA 
TCTGAGCAAT GGATCTTCAG GCTCTACGTG AGCATAGGCT GGGGTGTTCC CCTGCTGTTT 
GTTGTCCCCT GGGGCATTGT CAAGTACCTC TATGAGGACG AGGGCTGCTG GACCAGGAAC 
TCCAACATGA ACTACTGGCT CATTATCCGG CTGCCCATTC TCTTTGCCAT TGGGGTGAAC 
TTCCTCATCT TTGTTCGGGT CATCTGCATC GTGGTATCCA AACTGAAGGC CAATCTCATG 
TGCAAGACAG ACATCAAATG CAGACTTGCC AAGTCCACGC TGACACTCAT CCCCCTGCTG 
GGGACTCATG AGGTCATCTT TGCCTTTGTG ATGGACGAGC ACGCCCGGGG GACCCTGCGC 
TTCATCAAGC TGTTTACAGA GCTCTCCTTC ACCTCCTTCC AGGGGCTGAT GGTGGCCATA 
TTATACTGCT TTGTCAACAA TGAGGTCCAG CTGGAATTTC GGAAGAGCTG GGAGCGCTGG 
CGGCTTGAGC ACTTGCACAT CCAGAGGGAC AGCAGCATGA AGCCCCTCAA GTGTCCCACC 
AGCAGCCTGA GCAGTGGAGC CACGGCGGGC AGCAGCATGT ACACAGCCAC TTGCCAGGCC 
TCCTGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_002053.3

Translation

MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS

Target ORF information:

RefSeq Version	NM_002062.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens glucagon-like peptide 1 receptor (GLP1R), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002062.3

ORF Insert Sequence:

ATGGCCGGCG CCCCCGGCCC GCTGCGCCTT GCGCTGCTGC TGCTCGGGAT GGTGGGCAGG 
GCCGGCCCCC GCCCCCAGGG TGCCACTGTG TCCCTCTGGG AGACGGTGCA GAAATGGCGA 
GAATACCGAC GCCAGTGCCA GCGCTCCCTG ACTGAGGATC CACCTCCTGC CACAGACTTG 
TTCTGCAACC GGACCTTCGA TGAATACGCC TGCTGGCCAG ATGGGGAGCC AGGCTCGTTC 
GTGAATGTCA GCTGCCCCTG GTACCTGCCC TGGGCCAGCA GTGTGCCGCA GGGCCACGTG 
TACCGGTTCT GCACAGCTGA AGGCCTCTGG CTGCAGAAGG ACAACTCCAG CCTGCCCTGG 
AGGGACTTGT CGGAGTGCGA GGAGTCCAAG CGAGGGGAAA GAAGCTCCCC GGAGGAGCAG 
CTCCTGTTCC TCTACATCAT CTACACGGTG GGCTACGCAC TCTCCTTCTC TGCTCTGGTT 
ATCGCCTCTG CGATCCTCCT CGGCTTCAGA CACCTGCACT GCACCAGGAA CTACATCCAC 
CTGAACCTGT TTGCATCCTT CATCCTGCGA GCATTGTCCG TCTTCATCAA GGACGCAGCC 
CTGAAGTGGA TGTATAGCAC AGCCGCCCAG CAGCACCAGT GGGATGGGCT CCTCTCCTAC 
CAGGACTCTC TGAGCTGCCG CCTGGTGTTT CTGCTCATGC AGTACTGTGT GGCGGCCAAT 
TACTACTGGC TCTTGGTGGA GGGCGTGTAC CTGTACACAC TGCTGGCCTT CTCGGTCTTA 
TCTGAGCAAT GGATCTTCAG GCTCTACGTG AGCATAGGCT GGGGTGTTCC CCTGCTGTTT 
GTTGTCCCCT GGGGCATTGT CAAGTACCTC TATGAGGACG AGGGCTGCTG GACCAGGAAC 
TCCAACATGA ACTACTGGCT CATTATCCGG CTGCCCATTC TCTTTGCCAT TGGGGTGAAC 
TTCCTCATCT TTGTTCGGGT CATCTGCATC GTGGTATCCA AACTGAAGGC CAATCTCATG 
TGCAAGACAG ACATCAAATG CAGACTTGCC AAGTCCACGC TGACACTCAT CCCCCTGCTG 
GGGACTCATG AGGTCATCTT TGCCTTTGTG ATGGACGAGC ACGCCCGGGG GACCCTGCGC 
TTCATCAAGC TGTTTACAGA GCTCTCCTTC ACCTCCTTCC AGGGGCTGAT GGTGGCCATA 
TTATACTGCT TTGTCAACAA TGAGGTCCAG CTGGAATTTC GGAAGAGCTG GGAGCGCTGG 
CGGCTTGAGC ACTTGCACAT CCAGAGGGAC AGCAGCATGA AGCCCCTCAA GTGTCCCACC 
AGCAGCCTGA GCAGTGGAGC CACGGCGGGC AGCAGCATGT ACACAGCCAC TTGCCAGGCC 
TCCTGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLP1R ( NM_002062.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002053.3 Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26898
Clone ID Related Accession (Same CDS sequence)	NM_002062.3 , NM_002062.4 , NM_002062.5
Accession Version	NM_002062.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	glucagon-like peptide 1 receptor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC113493.1, AL035690.10, KR138540.1 and CK819862.1. On Apr 16, 2016 this sequence version replaced NM_002062.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the supported protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC113493.1, U01157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150585, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCCGGCG CCCCCGGCCC GCTGCGCCTT GCGCTGCTGC TGCTCGGGAT GGTGGGCAGG 
GCCGGCCCCC GCCCCCAGGG TGCCACTGTG TCCCTCTGGG AGACGGTGCA GAAATGGCGA 
GAATACCGAC GCCAGTGCCA GCGCTCCCTG ACTGAGGATC CACCTCCTGC CACAGACTTG 
TTCTGCAACC GGACCTTCGA TGAATACGCC TGCTGGCCAG ATGGGGAGCC AGGCTCGTTC 
GTGAATGTCA GCTGCCCCTG GTACCTGCCC TGGGCCAGCA GTGTGCCGCA GGGCCACGTG 
TACCGGTTCT GCACAGCTGA AGGCCTCTGG CTGCAGAAGG ACAACTCCAG CCTGCCCTGG 
AGGGACTTGT CGGAGTGCGA GGAGTCCAAG CGAGGGGAAA GAAGCTCCCC GGAGGAGCAG 
CTCCTGTTCC TCTACATCAT CTACACGGTG GGCTACGCAC TCTCCTTCTC TGCTCTGGTT 
ATCGCCTCTG CGATCCTCCT CGGCTTCAGA CACCTGCACT GCACCAGGAA CTACATCCAC 
CTGAACCTGT TTGCATCCTT CATCCTGCGA GCATTGTCCG TCTTCATCAA GGACGCAGCC 
CTGAAGTGGA TGTATAGCAC AGCCGCCCAG CAGCACCAGT GGGATGGGCT CCTCTCCTAC 
CAGGACTCTC TGAGCTGCCG CCTGGTGTTT CTGCTCATGC AGTACTGTGT GGCGGCCAAT 
TACTACTGGC TCTTGGTGGA GGGCGTGTAC CTGTACACAC TGCTGGCCTT CTCGGTCTTA 
TCTGAGCAAT GGATCTTCAG GCTCTACGTG AGCATAGGCT GGGGTGTTCC CCTGCTGTTT 
GTTGTCCCCT GGGGCATTGT CAAGTACCTC TATGAGGACG AGGGCTGCTG GACCAGGAAC 
TCCAACATGA ACTACTGGCT CATTATCCGG CTGCCCATTC TCTTTGCCAT TGGGGTGAAC 
TTCCTCATCT TTGTTCGGGT CATCTGCATC GTGGTATCCA AACTGAAGGC CAATCTCATG 
TGCAAGACAG ACATCAAATG CAGACTTGCC AAGTCCACGC TGACACTCAT CCCCCTGCTG 
GGGACTCATG AGGTCATCTT TGCCTTTGTG ATGGACGAGC ACGCCCGGGG GACCCTGCGC 
TTCATCAAGC TGTTTACAGA GCTCTCCTTC ACCTCCTTCC AGGGGCTGAT GGTGGCCATA 
TTATACTGCT TTGTCAACAA TGAGGTCCAG CTGGAATTTC GGAAGAGCTG GGAGCGCTGG 
CGGCTTGAGC ACTTGCACAT CCAGAGGGAC AGCAGCATGA AGCCCCTCAA GTGTCCCACC 
AGCAGCCTGA GCAGTGGAGC CACGGCGGGC AGCAGCATGT ACACAGCCAC TTGCCAGGCC 
TCCTGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002053.3
CDS	61..1452
Translation	MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS

Target ORF information:

RefSeq Version	NM_002062.4
Organism	Homo sapiens(human)
Definition	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002062.4

ORF Insert Sequence:

ATGGCCGGCG CCCCCGGCCC GCTGCGCCTT GCGCTGCTGC TGCTCGGGAT GGTGGGCAGG 
GCCGGCCCCC GCCCCCAGGG TGCCACTGTG TCCCTCTGGG AGACGGTGCA GAAATGGCGA 
GAATACCGAC GCCAGTGCCA GCGCTCCCTG ACTGAGGATC CACCTCCTGC CACAGACTTG 
TTCTGCAACC GGACCTTCGA TGAATACGCC TGCTGGCCAG ATGGGGAGCC AGGCTCGTTC 
GTGAATGTCA GCTGCCCCTG GTACCTGCCC TGGGCCAGCA GTGTGCCGCA GGGCCACGTG 
TACCGGTTCT GCACAGCTGA AGGCCTCTGG CTGCAGAAGG ACAACTCCAG CCTGCCCTGG 
AGGGACTTGT CGGAGTGCGA GGAGTCCAAG CGAGGGGAAA GAAGCTCCCC GGAGGAGCAG 
CTCCTGTTCC TCTACATCAT CTACACGGTG GGCTACGCAC TCTCCTTCTC TGCTCTGGTT 
ATCGCCTCTG CGATCCTCCT CGGCTTCAGA CACCTGCACT GCACCAGGAA CTACATCCAC 
CTGAACCTGT TTGCATCCTT CATCCTGCGA GCATTGTCCG TCTTCATCAA GGACGCAGCC 
CTGAAGTGGA TGTATAGCAC AGCCGCCCAG CAGCACCAGT GGGATGGGCT CCTCTCCTAC 
CAGGACTCTC TGAGCTGCCG CCTGGTGTTT CTGCTCATGC AGTACTGTGT GGCGGCCAAT 
TACTACTGGC TCTTGGTGGA GGGCGTGTAC CTGTACACAC TGCTGGCCTT CTCGGTCTTA 
TCTGAGCAAT GGATCTTCAG GCTCTACGTG AGCATAGGCT GGGGTGTTCC CCTGCTGTTT 
GTTGTCCCCT GGGGCATTGT CAAGTACCTC TATGAGGACG AGGGCTGCTG GACCAGGAAC 
TCCAACATGA ACTACTGGCT CATTATCCGG CTGCCCATTC TCTTTGCCAT TGGGGTGAAC 
TTCCTCATCT TTGTTCGGGT CATCTGCATC GTGGTATCCA AACTGAAGGC CAATCTCATG 
TGCAAGACAG ACATCAAATG CAGACTTGCC AAGTCCACGC TGACACTCAT CCCCCTGCTG 
GGGACTCATG AGGTCATCTT TGCCTTTGTG ATGGACGAGC ACGCCCGGGG GACCCTGCGC 
TTCATCAAGC TGTTTACAGA GCTCTCCTTC ACCTCCTTCC AGGGGCTGAT GGTGGCCATA 
TTATACTGCT TTGTCAACAA TGAGGTCCAG CTGGAATTTC GGAAGAGCTG GGAGCGCTGG 
CGGCTTGAGC ACTTGCACAT CCAGAGGGAC AGCAGCATGA AGCCCCTCAA GTGTCCCACC 
AGCAGCCTGA GCAGTGGAGC CACGGCGGGC AGCAGCATGT ACACAGCCAC TTGCCAGGCC 
TCCTGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLP1R ( NM_002062.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002053.3 Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26898
Clone ID Related Accession (Same CDS sequence)	NM_002062.3 , NM_002062.4 , NM_002062.5
Accession Version	NM_002062.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	glucagon-like peptide 1 receptor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC113493.1, AL035690.10, KR138540.1 and CK819862.1. On Nov 22, 2018 this sequence version replaced NM_002062.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the supported protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC113493.1, U01157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150585, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373256.5/ ENSP00000362353.4 RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGGCG CCCCCGGCCC GCTGCGCCTT GCGCTGCTGC TGCTCGGGAT GGTGGGCAGG 
GCCGGCCCCC GCCCCCAGGG TGCCACTGTG TCCCTCTGGG AGACGGTGCA GAAATGGCGA 
GAATACCGAC GCCAGTGCCA GCGCTCCCTG ACTGAGGATC CACCTCCTGC CACAGACTTG 
TTCTGCAACC GGACCTTCGA TGAATACGCC TGCTGGCCAG ATGGGGAGCC AGGCTCGTTC 
GTGAATGTCA GCTGCCCCTG GTACCTGCCC TGGGCCAGCA GTGTGCCGCA GGGCCACGTG 
TACCGGTTCT GCACAGCTGA AGGCCTCTGG CTGCAGAAGG ACAACTCCAG CCTGCCCTGG 
AGGGACTTGT CGGAGTGCGA GGAGTCCAAG CGAGGGGAAA GAAGCTCCCC GGAGGAGCAG 
CTCCTGTTCC TCTACATCAT CTACACGGTG GGCTACGCAC TCTCCTTCTC TGCTCTGGTT 
ATCGCCTCTG CGATCCTCCT CGGCTTCAGA CACCTGCACT GCACCAGGAA CTACATCCAC 
CTGAACCTGT TTGCATCCTT CATCCTGCGA GCATTGTCCG TCTTCATCAA GGACGCAGCC 
CTGAAGTGGA TGTATAGCAC AGCCGCCCAG CAGCACCAGT GGGATGGGCT CCTCTCCTAC 
CAGGACTCTC TGAGCTGCCG CCTGGTGTTT CTGCTCATGC AGTACTGTGT GGCGGCCAAT 
TACTACTGGC TCTTGGTGGA GGGCGTGTAC CTGTACACAC TGCTGGCCTT CTCGGTCTTA 
TCTGAGCAAT GGATCTTCAG GCTCTACGTG AGCATAGGCT GGGGTGTTCC CCTGCTGTTT 
GTTGTCCCCT GGGGCATTGT CAAGTACCTC TATGAGGACG AGGGCTGCTG GACCAGGAAC 
TCCAACATGA ACTACTGGCT CATTATCCGG CTGCCCATTC TCTTTGCCAT TGGGGTGAAC 
TTCCTCATCT TTGTTCGGGT CATCTGCATC GTGGTATCCA AACTGAAGGC CAATCTCATG 
TGCAAGACAG ACATCAAATG CAGACTTGCC AAGTCCACGC TGACACTCAT CCCCCTGCTG 
GGGACTCATG AGGTCATCTT TGCCTTTGTG ATGGACGAGC ACGCCCGGGG GACCCTGCGC 
TTCATCAAGC TGTTTACAGA GCTCTCCTTC ACCTCCTTCC AGGGGCTGAT GGTGGCCATA 
TTATACTGCT TTGTCAACAA TGAGGTCCAG CTGGAATTTC GGAAGAGCTG GGAGCGCTGG 
CGGCTTGAGC ACTTGCACAT CCAGAGGGAC AGCAGCATGA AGCCCCTCAA GTGTCCCACC 
AGCAGCCTGA GCAGTGGAGC CACGGCGGGC AGCAGCATGT ACACAGCCAC TTGCCAGGCC 
TCCTGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002053.3
CDS	61..1452
Translation	MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS

Target ORF information:

RefSeq Version	NM_002062.5
Organism	Homo sapiens(human)
Definition	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002062.5

ORF Insert Sequence:

ATGGCCGGCG CCCCCGGCCC GCTGCGCCTT GCGCTGCTGC TGCTCGGGAT GGTGGGCAGG 
GCCGGCCCCC GCCCCCAGGG TGCCACTGTG TCCCTCTGGG AGACGGTGCA GAAATGGCGA 
GAATACCGAC GCCAGTGCCA GCGCTCCCTG ACTGAGGATC CACCTCCTGC CACAGACTTG 
TTCTGCAACC GGACCTTCGA TGAATACGCC TGCTGGCCAG ATGGGGAGCC AGGCTCGTTC 
GTGAATGTCA GCTGCCCCTG GTACCTGCCC TGGGCCAGCA GTGTGCCGCA GGGCCACGTG 
TACCGGTTCT GCACAGCTGA AGGCCTCTGG CTGCAGAAGG ACAACTCCAG CCTGCCCTGG 
AGGGACTTGT CGGAGTGCGA GGAGTCCAAG CGAGGGGAAA GAAGCTCCCC GGAGGAGCAG 
CTCCTGTTCC TCTACATCAT CTACACGGTG GGCTACGCAC TCTCCTTCTC TGCTCTGGTT 
ATCGCCTCTG CGATCCTCCT CGGCTTCAGA CACCTGCACT GCACCAGGAA CTACATCCAC 
CTGAACCTGT TTGCATCCTT CATCCTGCGA GCATTGTCCG TCTTCATCAA GGACGCAGCC 
CTGAAGTGGA TGTATAGCAC AGCCGCCCAG CAGCACCAGT GGGATGGGCT CCTCTCCTAC 
CAGGACTCTC TGAGCTGCCG CCTGGTGTTT CTGCTCATGC AGTACTGTGT GGCGGCCAAT 
TACTACTGGC TCTTGGTGGA GGGCGTGTAC CTGTACACAC TGCTGGCCTT CTCGGTCTTA 
TCTGAGCAAT GGATCTTCAG GCTCTACGTG AGCATAGGCT GGGGTGTTCC CCTGCTGTTT 
GTTGTCCCCT GGGGCATTGT CAAGTACCTC TATGAGGACG AGGGCTGCTG GACCAGGAAC 
TCCAACATGA ACTACTGGCT CATTATCCGG CTGCCCATTC TCTTTGCCAT TGGGGTGAAC 
TTCCTCATCT TTGTTCGGGT CATCTGCATC GTGGTATCCA AACTGAAGGC CAATCTCATG 
TGCAAGACAG ACATCAAATG CAGACTTGCC AAGTCCACGC TGACACTCAT CCCCCTGCTG 
GGGACTCATG AGGTCATCTT TGCCTTTGTG ATGGACGAGC ACGCCCGGGG GACCCTGCGC 
TTCATCAAGC TGTTTACAGA GCTCTCCTTC ACCTCCTTCC AGGGGCTGAT GGTGGCCATA 
TTATACTGCT TTGTCAACAA TGAGGTCCAG CTGGAATTTC GGAAGAGCTG GGAGCGCTGG 
CGGCTTGAGC ACTTGCACAT CCAGAGGGAC AGCAGCATGA AGCCCCTCAA GTGTCCCACC 
AGCAGCCTGA GCAGTGGAGC CACGGCGGGC AGCAGCATGT ACACAGCCAC TTGCCAGGCC 
TCCTGCAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLP1R ( XM_017010750.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016866239.1 Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant X4, mRNA.

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CloneID	OHu96544
Clone ID Related Accession (Same CDS sequence)	XM_017010750.1
Accession Version	XM_017010750.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1407bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	glucagon-like peptide 1 receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGATTG AGAAACCAAG TGTGTTAGGG GGTGAGGGGG CAGGAGAGGG GCTGGCTGAA 
CCCACAGGCC TCCCATATAT GCCCTCCCCC CAGGGTGCCA CTGTGTCCCT CTGGGAGACG 
GTGCAGAAAT GGCGAGAATA CCGACGCCAG TGCCAGCGCT CCCTGACTGA GGATCCACCT 
CCTGCCACAG ACTTGTTCTG CAACCGGACC TTCGATGAAT ACGCCTGCTG GCCAGATGGG 
GAGCCAGGCT CGTTCGTGAA TGTCAGCTGC CCCTGGTACC TGCCCTGGGC CAGCAGTGTG 
CCGCAGGGCC ACGTGTACCG GTTCTGCACA GCTGAAGGCC TCTGGCTGCA GAAGGACAAC 
TCCAGCCTGC CCTGGAGGGA CTTGTCGGAG TGCGAGGAGT CCAAGCGAGG GGAAAGAAGC 
TCCCCGGAGG AGCAGCTCCT GTTCCTCTAC ATCATCTACA CGGTGGGCTA CGCACTCTCC 
TTCTCTGCTC TGGTTATCGC CTCTGCGATC CTCCTCGGCT TCAGACACCT GCACTGCACC 
AGGAACTACA TCCACCTGAA CCTGTTTGCA TCCTTCATCC TGCGAGCATT GTCCGTCTTC 
ATCAAGGACG CAGCCCTGAA GTGGATGTAT AGCACAGCCG CCCAGCAGCA CCAGTGGGAT 
GGGCTCCTCT CCTACCAGGA CTCTCTGAGC TGCCGCCTGG TGTTTCTGCT CATGCAGTAC 
TGTGTGGCGG CCAATTACTA CTGGCTCTTG GTGGAGGGCG TGTACCTGTA CACACTGCTG 
GCCTTCTCGG TCTTATCTGA GCAATGGATC TTCAGGCTCT ACGTGAGCAT AGGCTGGGGT 
GTTCCCCTGC TGTTTGTTGT CCCCTGGGGC ATTGTCAAGT ACCTCTATGA GGACGAGGGC 
TGCTGGACCA GGAACTCCAA CATGAACTAC TGGCTCATTA TCCGGCTGCC CATTCTCTTT 
GCCATTGGGG TGAACTTCCT CATCTTTGTT CGGGTCATCT GCATCGTGGT ATCCAAACTG 
AAGGCCAATC TCATGTGCAA GACAGACATC AAATGCAGAC TTGCCAAGTC CACGCTGACA 
CTCATCCCCC TGCTGGGGAC TCATGAGGTC ATCTTTGCCT TTGTGATGGA CGAGCACGCC 
CGGGGGACCC TGCGCTTCAT CAAGCTGTTT ACAGAGCTCT CCTTCACCTC CTTCCAGGGG 
CTGATGGTGG CCATATTATA CTGCTTTGTC AACAATGAGG TCCAGCTGGA ATTTCGGAAG 
AGCTGGGAGC GCTGGCGGCT TGAGCACTTG CACATCCAGA GGGACAGCAG CATGAAGCCC 
CTCAAGTGTC CCACCAGCAG CCTGAGCAGT GGAGCCACGG CGGGCAGCAG CATGTACACA 
GCCACTTGCC AGGCCTCCTG CAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866239.1
CDS	581..1987
Translation	MEIEKPSVLGGEGAGEGLAEPTGLPYMPSPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS

Target ORF information:

RefSeq Version	XM_017010750.1
Organism	Homo sapiens(human)
Definition	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010750.1

ORF Insert Sequence:

ATGGAGATTG AGAAACCAAG TGTGTTAGGG GGTGAGGGGG CAGGAGAGGG GCTGGCTGAA 
CCCACAGGCC TCCCATATAT GCCCTCCCCC CAGGGTGCCA CTGTGTCCCT CTGGGAGACG 
GTGCAGAAAT GGCGAGAATA CCGACGCCAG TGCCAGCGCT CCCTGACTGA GGATCCACCT 
CCTGCCACAG ACTTGTTCTG CAACCGGACC TTCGATGAAT ACGCCTGCTG GCCAGATGGG 
GAGCCAGGCT CGTTCGTGAA TGTCAGCTGC CCCTGGTACC TGCCCTGGGC CAGCAGTGTG 
CCGCAGGGCC ACGTGTACCG GTTCTGCACA GCTGAAGGCC TCTGGCTGCA GAAGGACAAC 
TCCAGCCTGC CCTGGAGGGA CTTGTCGGAG TGCGAGGAGT CCAAGCGAGG GGAAAGAAGC 
TCCCCGGAGG AGCAGCTCCT GTTCCTCTAC ATCATCTACA CGGTGGGCTA CGCACTCTCC 
TTCTCTGCTC TGGTTATCGC CTCTGCGATC CTCCTCGGCT TCAGACACCT GCACTGCACC 
AGGAACTACA TCCACCTGAA CCTGTTTGCA TCCTTCATCC TGCGAGCATT GTCCGTCTTC 
ATCAAGGACG CAGCCCTGAA GTGGATGTAT AGCACAGCCG CCCAGCAGCA CCAGTGGGAT 
GGGCTCCTCT CCTACCAGGA CTCTCTGAGC TGCCGCCTGG TGTTTCTGCT CATGCAGTAC 
TGTGTGGCGG CCAATTACTA CTGGCTCTTG GTGGAGGGCG TGTACCTGTA CACACTGCTG 
GCCTTCTCGG TCTTATCTGA GCAATGGATC TTCAGGCTCT ACGTGAGCAT AGGCTGGGGT 
GTTCCCCTGC TGTTTGTTGT CCCCTGGGGC ATTGTCAAGT ACCTCTATGA GGACGAGGGC 
TGCTGGACCA GGAACTCCAA CATGAACTAC TGGCTCATTA TCCGGCTGCC CATTCTCTTT 
GCCATTGGGG TGAACTTCCT CATCTTTGTT CGGGTCATCT GCATCGTGGT ATCCAAACTG 
AAGGCCAATC TCATGTGCAA GACAGACATC AAATGCAGAC TTGCCAAGTC CACGCTGACA 
CTCATCCCCC TGCTGGGGAC TCATGAGGTC ATCTTTGCCT TTGTGATGGA CGAGCACGCC 
CGGGGGACCC TGCGCTTCAT CAAGCTGTTT ACAGAGCTCT CCTTCACCTC CTTCCAGGGG 
CTGATGGTGG CCATATTATA CTGCTTTGTC AACAATGAGG TCCAGCTGGA ATTTCGGAAG 
AGCTGGGAGC GCTGGCGGCT TGAGCACTTG CACATCCAGA GGGACAGCAG CATGAAGCCC 
CTCAAGTGTC CCACCAGCAG CCTGAGCAGT GGAGCCACGG CGGGCAGCAG CATGTACACA 
GCCACTTGCC AGGCCTCCTG CAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GLP1R ( XM_017010751.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016866240.1 Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant X5, mRNA.

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CloneID	OHu96545
Clone ID Related Accession (Same CDS sequence)	XM_017010751.1
Accession Version	XM_017010751.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	glucagon-like peptide 1 receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGATTG AGAAACCAAG TGTGTTAGGG GGTGAGGGGG CAGGAGAGGG GCTGGCTGAA 
CCCACAGGCC TCCCATATAT GCCCTCCCCC CAGGGTGCCA CTGTGTCCCT CTGGGAGACG 
GTGCAGAAAT GGCGAGAATA CCGACGCCAG TGCCAGCGCT CCCTGACTGA GGATCCACCT 
CCTGCCACAG ACTTGTTCTG CAACCGGACC TTCGATGAAT ACGCCTGCTG GCCAGATGGG 
GAGCCAGGCT CGTTCGTGAA TGTCAGCTGC CCCTGGTACC TGCCCTGGGC CAGCAGTGTG 
CCGCAGGGCC ACGTGTACCG GTTCTGCACA GCTGAAGGCC TCTGGCTGCA GAAGGACAAC 
TCCAGCCTGC CCTGGAGGGA CTTGTCGGAG TGCGAGGAGT CCAAGCGAGG GGAAAGAAGC 
TCCCCGGAGG AGCAGCTCCT GTTCCTCTAC ATCATCTACA CGGTGGGCTA CGCACTCTCC 
TTCTCTGCTC TGGTTATCGC CTCTGCGATC CTCCTCGGCT TCAGACACCT GCACTGCACC 
AGGAACTACA TCCACCTGAA CCTGTTTGCA TCCTTCATCC TGCGAGCATT GTCCGTCTTC 
ATCAAGGACG CAGCCCTGAA GTGGATGTAT AGCACAGCCG CCCAGCAGCA CCAGTGGGAT 
GGGCTCCTCT CCTACCAGGA CTCTCTGAGC TGCCGCCTGG TGTTTCTGCT CATGCAGTAC 
TGTGTGGCGG CCAATTACTA CTGGCTCTTG GTGGAGGGCG TGTACCTGTA CACACTGCTG 
GCCTTCTCGG TCTTATCTGA GCAATGGATC TTCAGGCTCT ACGTGAGCAT AGGCTGGGCT 
GCTGGACCAG GAACTCCAAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866240.1
CDS	584..1447
Translation	MEIEKPSVLGGEGAGEGLAEPTGLPYMPSPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWAAGPGTPT

Target ORF information:

RefSeq Version	XM_017010751.1
Organism	Homo sapiens(human)
Definition	Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010751.1

ORF Insert Sequence:

ATGGAGATTG AGAAACCAAG TGTGTTAGGG GGTGAGGGGG CAGGAGAGGG GCTGGCTGAA 
CCCACAGGCC TCCCATATAT GCCCTCCCCC CAGGGTGCCA CTGTGTCCCT CTGGGAGACG 
GTGCAGAAAT GGCGAGAATA CCGACGCCAG TGCCAGCGCT CCCTGACTGA GGATCCACCT 
CCTGCCACAG ACTTGTTCTG CAACCGGACC TTCGATGAAT ACGCCTGCTG GCCAGATGGG 
GAGCCAGGCT CGTTCGTGAA TGTCAGCTGC CCCTGGTACC TGCCCTGGGC CAGCAGTGTG 
CCGCAGGGCC ACGTGTACCG GTTCTGCACA GCTGAAGGCC TCTGGCTGCA GAAGGACAAC 
TCCAGCCTGC CCTGGAGGGA CTTGTCGGAG TGCGAGGAGT CCAAGCGAGG GGAAAGAAGC 
TCCCCGGAGG AGCAGCTCCT GTTCCTCTAC ATCATCTACA CGGTGGGCTA CGCACTCTCC 
TTCTCTGCTC TGGTTATCGC CTCTGCGATC CTCCTCGGCT TCAGACACCT GCACTGCACC 
AGGAACTACA TCCACCTGAA CCTGTTTGCA TCCTTCATCC TGCGAGCATT GTCCGTCTTC 
ATCAAGGACG CAGCCCTGAA GTGGATGTAT AGCACAGCCG CCCAGCAGCA CCAGTGGGAT 
GGGCTCCTCT CCTACCAGGA CTCTCTGAGC TGCCGCCTGG TGTTTCTGCT CATGCAGTAC 
TGTGTGGCGG CCAATTACTA CTGGCTCTTG GTGGAGGGCG TGTACCTGTA CACACTGCTG 
GCCTTCTCGG TCTTATCTGA GCAATGGATC TTCAGGCTCT ACGTGAGCAT AGGCTGGGCT 
GCTGGACCAG GAACTCCAAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-?B Activation.
Endocrinology158(12)4218-4232(2017 Dec)
Iwaya C,Nomiyama T,Komatsu S,Kawanami T,Tsutsumi Y,Hamaguchi Y,Horikawa T,Yoshinaga Y,Yamashita S,Tanaka T,Terawaki Y,Tanabe M,Nabeshima K,Iwasaki A,Yanase T

Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor.
PloS one12(6)e0179568(2017)
Cai Y,Liu Y,Culhane KJ,DeVree BT,Yang Y,Sunahara RK,Yan ECY

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GLP1R cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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