TOR1B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TOR1B
Entrez Gene ID	27348
Full Name	torsin family 1 member B
Synonyms	DQ1
General protein information	Preferred Names torsin family 1 member B Names torsin-1B torsin ATPase-1B torsin B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.11
Summary	The protein encoded by this gene is an ATPase found primarily in the endoplasmic reticulum and nuclear envelope. This gene has a highly-similar neighboring gene, TOR1A, that encodes a protein that is likely to interact in a complex with this protein. Finally, this protein may act as a chaperone and play a role in maintaining the integrity of the nuclear envelope and endoplasmic reticulum. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015].
Disorder MIM:	608050

mRNA and Protein(s)

mRNA	Protein	Name
NM_001317894.2	NP_001304823.1	torsin-1B isoform 3 precursor
NM_014506.2	NP_055321.1	torsin-1B isoform 1 precursor
NM_014506.1	NP_055321.1	torsin-1B precursor
NM_001317893.2	NP_001304822.1	torsin-1B isoform 2 precursor
XM_005251927.3	XP_005251984.1	torsin-1B isoform X1
NM_001317894.1	NP_001304823.1	torsin-1B isoform 3 precursor
NM_001317893.1	NP_001304822.1	torsin-1B isoform 2 precursor
NM_014506.3	NP_055321.1	torsin-1B isoform 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	TOR1B	NP_055321.1
Gallus gallus (chicken)	TOR1B	XP_415473.3
Pan troglodytes (chimpanzee)	TOR1B	XP_001164236.1
	TOR1B	XP_001107456.1
Caenorhabditis elegans (roundworm)	tor-1	NP_502684.2
Bos taurus (cattle)	TOR1B	XP_002691721.2
Danio rerio (zebrafish)	tor1	NP_001186944.1
Xenopus tropicalis (tropical clawed frog)	tor1a	NP_001039096.1
Rattus norvegicus (Norway rat)	Tor1b	NP_001034286.1
Canis lupus familiaris (dog)	TOR1B	XP_003639349.1
Mus musculus (house mouse)	Tor1b	NP_598434.2
Caenorhabditis elegans (roundworm)	ooc-5	NP_495917.1
Caenorhabditis elegans (roundworm)	tor-2	NP_502683.1

Gene Ontology
Bibliography

Related articles in PubMed

Arresting a Torsin ATPase reshapes the endoplasmic reticulum.
Rose AE, Zhao C, Turner EM, Steyer AM, Schlieker C
The Journal of biological chemistry289(1)552-64(2014 Jan)

Regulation of Torsin ATPases by LAP1 and LULL1.
Zhao C, Brown RS, Chase AR, Eisele MR, Schlieker C
Proceedings of the National Academy of Sciences of the United States of America110(17)E1545-54(2013 Apr)

Genetic evidence for an association of the TOR1A locus with segmental/focal dystonia.
Sharma N, Franco RA Jr, Kuster JK, Mitchell AA, Fuchs T, Saunders-Pullman R, Raymond D, Brin MF, Blitzer A, Bressman SB, Ozelius LJ
Movement disorders : official journal of the Movement Disorder Society25(13)2183-7(2010 Oct)

Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.
Jungwirth M, Dear ML, Brown P, Holbrook K, Goodchild R
Human molecular genetics19(5)888-900(2010 Mar)

Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia.
Kamm C, Asmus F, Mueller J, Mayer P, Sharma M, Muller UJ, Beckert S, Ehling R, Illig T, Wichmann HE, Poewe W, Mueller JC, Gasser T
Neurology67(10)1857-9(2006 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the induction of a conditional, dominant-negative TorsinB variant provokes a profound reorganization of the endomembrane system into foci containing double membrane structures that are derived from the ER.
Title: Arresting a Torsin ATPase reshapes the endoplasmic reticulum.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic evidence for an association of the TOR1A locus with segmental/focal dystonia.

Observational study of gene-disease association. (HuGE Navigator)
Title: Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia.

torsinB is needed for developmental events occurring in the early postnatal phase and is necessary for functional activity throughout life
Title: TorsinB expression in the developing human brain.

The following TOR1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOR1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28345	NM_014506.3 Latest version!	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu100771	NM_001317893.2 Latest version!	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu100777	NM_001317894.2 Latest version!	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu43202	XM_005251927.3 Latest version!	Homo sapiens torsin family 1 member B (TOR1B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu28345	NM_014506.1	Homo sapiens torsin family 1, member B (torsin B) (TOR1B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu100777	NM_001317894.1	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu100771	NM_001317893.1	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu28345	NM_014506.2	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TOR1B ( NM_014506.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055321.1 Homo sapiens torsin family 1 member B (TOR1B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28345
Clone ID Related Accession (Same CDS sequence)	NM_014506.2 , NM_014506.1 , NM_014506.3
Accession Version	NM_014506.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-24
Organism	Homo sapiens(human)
Product	torsin-1B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP366330.1, AF317129.1 and BU633792.1. On Dec 12, 2015 this sequence version replaced NM_014506.1. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1660807.25360.1, SRR1803611.61390.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAG TGGCCTGTGG 
CACAGTGGAC TGATCGACAA AAACCTCATT GATTACTTTA TCCCCTTCCT GCCTTTGGAG 
TACAGACATG TGAAAATGTG TGTGAGGGCC GAGATGAGGG CCCGTGGTTC TGCCATAGAT 
GAAGACATTG TCACAAGAGT GGCAGAGGAA ATGACGTTTT TCCCCAGAGA CGAGAAAATC 
TACTCAGACA AGGGCTGCAA GACTGTGCAG TCGCGGCTGG ATTTCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055321.1
CDS	71..1081
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAIDEDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDFH

Target ORF information:

RefSeq Version	NM_014506.2
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014506.2

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAG TGGCCTGTGG 
CACAGTGGAC TGATCGACAA AAACCTCATT GATTACTTTA TCCCCTTCCT GCCTTTGGAG 
TACAGACATG TGAAAATGTG TGTGAGGGCC GAGATGAGGG CCCGTGGTTC TGCCATAGAT 
GAAGACATTG TCACAAGAGT GGCAGAGGAA ATGACGTTTT TCCCCAGAGA CGAGAAAATC 
TACTCAGACA AGGGCTGCAA GACTGTGCAG TCGCGGCTGG ATTTCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR1B ( NM_014506.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_055321.1 Homo sapiens torsin family 1, member B (torsin B) (TOR1B), mRNA.

Price & Availability↑

CloneID	OHu28345
Clone ID Related Accession (Same CDS sequence)	NM_014506.2 , NM_014506.1 , NM_014506.3
Accession Version	NM_014506.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	torsin-1B precursor
Comment

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAG TGGCCTGTGG 
CACAGTGGAC TGATCGACAA AAACCTCATT GATTACTTTA TCCCCTTCCT GCCTTTGGAG 
TACAGACATG TGAAAATGTG TGTGAGGGCC GAGATGAGGG CCCGTGGTTC TGCCATAGAT 
GAAGACATTG TCACAAGAGT GGCAGAGGAA ATGACGTTTT TCCCCAGAGA CGAGAAAATC 
TACTCAGACA AGGGCTGCAA GACTGTGCAG TCGCGGCTGG ATTTCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055321.1
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAIDEDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDFH

Target ORF information:

RefSeq Version	NM_014506.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens torsin family 1, member B (torsin B) (TOR1B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014506.1

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAG TGGCCTGTGG 
CACAGTGGAC TGATCGACAA AAACCTCATT GATTACTTTA TCCCCTTCCT GCCTTTGGAG 
TACAGACATG TGAAAATGTG TGTGAGGGCC GAGATGAGGG CCCGTGGTTC TGCCATAGAT 
GAAGACATTG TCACAAGAGT GGCAGAGGAA ATGACGTTTT TCCCCAGAGA CGAGAAAATC 
TACTCAGACA AGGGCTGCAA GACTGTGCAG TCGCGGCTGG ATTTCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR1B ( NM_014506.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055321.1 Homo sapiens torsin family 1 member B (TOR1B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28345
Clone ID Related Accession (Same CDS sequence)	NM_014506.2 , NM_014506.1 , NM_014506.3
Accession Version	NM_014506.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	torsin-1B isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158207.15. On Nov 23, 2018 this sequence version replaced NM_014506.2. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AF317129.1, SRR1660807.25360.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000259339.7/ ENSP00000259339.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAG TGGCCTGTGG 
CACAGTGGAC TGATCGACAA AAACCTCATT GATTACTTTA TCCCCTTCCT GCCTTTGGAG 
TACAGACATG TGAAAATGTG TGTGAGGGCC GAGATGAGGG CCCGTGGTTC TGCCATAGAT 
GAAGACATTG TCACAAGAGT GGCAGAGGAA ATGACGTTTT TCCCCAGAGA CGAGAAAATC 
TACTCAGACA AGGGCTGCAA GACTGTGCAG TCGCGGCTGG ATTTCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055321.1
CDS	30..1040
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAIDEDIVTRVAEEMTFFPRDEKIYSDKGCKTVQSRLDFH

Target ORF information:

RefSeq Version	NM_014506.3
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014506.3

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAG TGGCCTGTGG 
CACAGTGGAC TGATCGACAA AAACCTCATT GATTACTTTA TCCCCTTCCT GCCTTTGGAG 
TACAGACATG TGAAAATGTG TGTGAGGGCC GAGATGAGGG CCCGTGGTTC TGCCATAGAT 
GAAGACATTG TCACAAGAGT GGCAGAGGAA ATGACGTTTT TCCCCAGAGA CGAGAAAATC 
TACTCAGACA AGGGCTGCAA GACTGTGCAG TCGCGGCTGG ATTTCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR1B ( NM_001317893.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001304822.1 Homo sapiens torsin family 1 member B (TOR1B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu100771
Clone ID Related Accession (Same CDS sequence)	NM_001317893.2 , NM_001317893.1
Accession Version	NM_001317893.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-31
Organism	Homo sapiens(human)
Product	torsin-1B isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158207.15. On Jun 1, 2019 this sequence version replaced NM_001317893.1. Transcript Variant: This variant (2) lacks an alternate exon and uses an alternate splice junction compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GAGTTCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001304822.1
CDS	30..680
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLRVH

Target ORF information:

RefSeq Version	NM_001317893.2
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001317893.2

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GAGTTCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR1B ( NM_001317893.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001304822.1 Homo sapiens torsin family 1 member B (TOR1B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu100771
Clone ID Related Accession (Same CDS sequence)	NM_001317893.2 , NM_001317893.1
Accession Version	NM_001317893.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	torsin-1B isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP366330.1, AI568476.1, AL158207.15, AF317129.1 and BU633792.1. Transcript Variant: This variant (2) lacks an alternate exon and uses an alternate splice junction compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GAGTTCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001304822.1
CDS	71..721
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLRVH

Target ORF information:

RefSeq Version	NM_001317893.1
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001317893.1

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GAGTTCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR1B ( NM_001317894.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001304823.1 Homo sapiens torsin family 1 member B (TOR1B), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu100777
Clone ID Related Accession (Same CDS sequence)	NM_001317894.2 , NM_001317894.1
Accession Version	NM_001317894.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	torsin-1B isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158207.15. On May 31, 2019 this sequence version replaced NM_001317894.1. Transcript Variant: This variant (3) lacks two alternate exons and uses an alternate splice junction compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BE315222.1, SRR1660803.389039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGAGTTC ACTGACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001304823.1
CDS	30..509
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQSSLT

Target ORF information:

RefSeq Version	NM_001317894.2
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001317894.2

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGAGTTC ACTGACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR1B ( NM_001317894.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001304823.1 Homo sapiens torsin family 1 member B (TOR1B), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu100777
Clone ID Related Accession (Same CDS sequence)	NM_001317894.2 , NM_001317894.1
Accession Version	NM_001317894.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	torsin-1B isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP366330.1, BE315222.1, AF317129.1 and BU633792.1. Transcript Variant: This variant (3) lacks two alternate exons and uses an alternate splice junction compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BE315222.1, SRR1660803.389039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGAGTTC ACTGACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001304823.1
CDS	71..550
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQSSLT

Target ORF information:

RefSeq Version	NM_001317894.1
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 1 member B (TOR1B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001317894.1

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGAGTTC ACTGACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR1B ( XM_005251927.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005251984.1 Homo sapiens torsin family 1 member B (TOR1B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu43202
Clone ID Related Accession (Same CDS sequence)	XM_005251927.3
Accession Version	XM_005251927.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	torsin-1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005251927.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAA GTTCACTGAC 
TTGAAGTATA CTCAGTTAAA ATCGGGGCTG GAGGTGCAGA CGGTGTCTGA CCGGAGGATG 
TGGCCGTGCC CGCCGAGCAC TCTTGATCTG AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005251984.1
CDS	66..941
Translation	MLRAGWLRGAAALALLLAARVVAAFEPITVGLAIGAASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQLKDLEPVLSVGVFNNKHKFTDLKYTQLKSGLEVQTVSDRRMWPCPPSTLDLS

Target ORF information:

RefSeq Version	XM_005251927.3
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 1 member B (TOR1B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005251927.3

ORF Insert Sequence:

ATGTTGCGGG CTGGGTGGCT CCGGGGCGCG GCGGCGCTGG CGCTGCTGCT GGCGGCCCGA 
GTGGTGGCGG CGTTCGAGCC CATCACCGTG GGCCTAGCCA TCGGGGCCGC GTCGGCCATC 
ACCGGCTACC TGTCCTACAA TGACATCTAC TGCCGCTTCG CCGAGTGCTG CCGCGAGGAG 
CGGCCGCTCA ACGCTTCGGC TCTCAAGCTG GATTTGGAGG AGAAGCTGTT TGGACAGCAT 
CTAGCCACGG AAGTGATTTT CAAGGCGCTG ACTGGCTTCA GGAACAACAA AAATCCCAAG 
AAACCACTGA CCCTTTCCTT ACACGGCTGG GCTGGCACAG GCAAGAATTT TGTCAGTCAA 
ATTGTGGCTG AAAATCTTCA CCCAAAAGGT CTGAAGAGTA ACTTTGTCCA CCTGTTTGTA 
TCGACTCTGC ACTTCCCTCA TGAGCAGAAG ATAAAACTGT ACCAGGACCA GTTACAGAAG 
TGGATCCGCG GTAATGTGAG TGCATGTGCG AACTCTGTTT TCATATTTGA CGAGATGGAT 
AAATTGCACC CCGGGATCAT TGACGCAATC AAGCCGTTTC TAGACTACTA CGAGCAGGTT 
GACGGAGTGT CTTACCGCAA AGCCATCTTC ATCTTTCTCA GCAATGCAGG CGGGGACCTT 
ATAACTAAGA CGGCTCTTGA CTTTTGGCGG GCCGGAAGAA AGAGGGAAGA CATTCAGCTG 
AAGGACCTGG AACCTGTACT GTCTGTCGGA GTCTTCAATA ATAAACACAA GTTCACTGAC 
TTGAAGTATA CTCAGTTAAA ATCGGGGCTG GAGGTGCAGA CGGTGTCTGA CCGGAGGATG 
TGGCCGTGCC CGCCGAGCAC TCTTGATCTG AGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Arresting a Torsin ATPase reshapes the endoplasmic reticulum.
The Journal of biological chemistry289(1)552-64(2014 Jan)
Rose AE,Zhao C,Turner EM,Steyer AM,Schlieker C

Regulation of Torsin ATPases by LAP1 and LULL1.
Proceedings of the National Academy of Sciences of the United States of America110(17)E1545-54(2013 Apr)
Zhao C,Brown RS,Chase AR,Eisele MR,Schlieker C

Genetic evidence for an association of the TOR1A locus with segmental/focal dystonia.
Movement disorders : official journal of the Movement Disorder Society25(13)2183-7(2010 Oct)
Sharma N,Franco RA Jr,Kuster JK,Mitchell AA,Fuchs T,Saunders-Pullman R,Raymond D,Brin MF,Blitzer A,Bressman SB,Ozelius LJ

Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.
Human molecular genetics19(5)888-900(2010 Mar)
Jungwirth M,Dear ML,Brown P,Holbrook K,Goodchild R

Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia.
Neurology67(10)1857-9(2006 Nov)
Kamm C,Asmus F,Mueller J,Mayer P,Sharma M,Muller UJ,Beckert S,Ehling R,Illig T,Wichmann HE,Poewe W,Mueller JC,Gasser T

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

TOR1B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報