CHMP2A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CHMP2A
Entrez Gene ID	27243
Full Name	charged multivesicular body protein 2A
Synonyms	BC-2,BC2,CHMP2,VPS2,VPS2A
General protein information	Preferred Names charged multivesicular body protein 2A Names charged multivesicular body protein 2a VPS2 homolog A chromatin modifying protein 2A putative breast adenocarcinoma marker (32kD) putative breast adenocarcinoma marker BC-2 vacuolar protein sorting-associated protein 2-1 vps2-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.43
Summary	CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610893

mRNA and Protein(s)

mRNA	Protein	Name
NM_014453.3	NP_055268.1	charged multivesicular body protein 2a
NM_198426.3	NP_940818.1	charged multivesicular body protein 2a
XM_005258746.2	XP_005258803.1	charged multivesicular body protein 2a isoform X1
NM_014453.4	NP_055268.1	charged multivesicular body protein 2a
XM_005258746.3	XP_005258803.1	charged multivesicular body protein 2a isoform X1
XM_005258747.3	XP_005258804.1	charged multivesicular body protein 2a isoform X1
NM_198426.2	NP_940818.1	charged multivesicular body protein 2a

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	chmp2a	NP_001005008.1
Homo sapiens (human)	CHMP2A	NP_940818.1
Canis lupus familiaris (dog)	CHMP2A	XP_850536.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001285	XP_321862.3
Caenorhabditis elegans (roundworm)	vps-2	NP_496717.1
Schizosaccharomyces pombe (fission yeast)	did4	NP_593871.3
Oryza sativa (rice)	Os07g0236800	NP_001059248.1
Bos taurus (cattle)	CHMP2A	NP_001029722.1
Mus musculus (house mouse)	Chmp2a	NP_081161.1
Rattus norvegicus (Norway rat)	Chmp2a	NP_001102376.1
Danio rerio (zebrafish)	bc2	NP_998682.1
Neurospora crassa	NCU00435	XP_956699.1
Pan troglodytes (chimpanzee)	CHMP2A	XP_003316813.1
	CHMP2A	XP_001099219.1
Gallus gallus (chicken)	CHMP2A	NP_001074361.1
Drosophila melanogaster (fruit fly)	vps2	NP_651455.1
Magnaporthe oryzae (rice blast fungus)	MGG_05208	XP_003712753.1
Saccharomyces cerevisiae (baker's yeast)	DID4	NP_012924.2
Kluyveromyces lactis	KLLA0B13343g	XP_452125.1
Eremothecium gossypii	AGOS_ABR002C	NP_982948.1
Arabidopsis thaliana (thale cress)	VPS2.1	NP_565336.1

Gene Ontology
Bibliography

Related articles in PubMed

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells.
Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A
Proceedings of the National Academy of Sciences of the United States of America114(11)E2166-E2175(2017 Mar)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H
Nature522(7555)231-5(2015 Jun)

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.
Cashikar AG, Shim S, Roth R, Maldazys MR, Heuser JE, Hanson PI
eLife3(2014 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that gamma2-adaptin in MVB sorting specifically interacts with the ESCRT subunits Vps28 and CHMP2A.
Title: ?2-Adaptin is functioning in the late endosomal sorting pathway and interacts with ESCRT-I and -III subunits.

study found the ESCRT-III proteins CHMP2A & CHMP3 could assemble in vitro into helical tubular structures that expose their membrane interaction sites on the outside of the tubule; VPS4 could bind on the inside of the tubule & disassemble the tubes
Title: Helical structures of ESCRT-III are disassembled by VPS4.

The following CHMP2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHMP2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09810	NM_198426.3 Latest version!	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu09810	NM_014453.4 Latest version!	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu52168	XM_005258747.3 Latest version!	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu52168	XM_005258746.3 Latest version!	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu09810	NM_014453.3	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu52168	XM_005258746.2	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu09810	NM_198426.2	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CHMP2A ( NM_014453.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055268.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09810
Clone ID Related Accession (Same CDS sequence)	NM_014453.3 , NM_198426.3 , NM_014453.4 , NM_198426.2
Accession Version	NM_014453.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 2a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP315111.1 and BC002502.2. On Jan 4, 2014 this sequence version replaced NM_014453.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.380297.1, SRR1163657.268935.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267753, SAMN03267755 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055268.1
CDS	162..830
Translation	MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD

Target ORF information:

RefSeq Version	NM_014453.3
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014453.3

ORF Insert Sequence:

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP2A ( NM_198426.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_940818.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09810
Clone ID Related Accession (Same CDS sequence)	NM_014453.3 , NM_198426.3 , NM_014453.4 , NM_198426.2
Accession Version	NM_198426.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 2a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC016630.6, CN305066.1 and BC002502.2. On May 31, 2019 this sequence version replaced NM_198426.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.295631.1, BC002502.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267753, SAMN03267755 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940818.1
CDS	266..934
Translation	MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD

Target ORF information:

RefSeq Version	NM_198426.3
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198426.3

ORF Insert Sequence:

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP2A ( NM_014453.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055268.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09810
Clone ID Related Accession (Same CDS sequence)	NM_014453.3 , NM_198426.3 , NM_014453.4 , NM_198426.2
Accession Version	NM_014453.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 2a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP315111.1 and BC002502.2. On May 17, 2019 this sequence version replaced NM_014453.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.687878.1, SRR5189652.111156.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267753, SAMN03267755 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000312547.7/ ENSP00000310440.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055268.1
CDS	143..811
Translation	MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD

Target ORF information:

RefSeq Version	NM_014453.4
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014453.4

ORF Insert Sequence:

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP2A ( NM_198426.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_940818.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09810
Clone ID Related Accession (Same CDS sequence)	NM_014453.3 , NM_198426.3 , NM_014453.4 , NM_198426.2
Accession Version	NM_198426.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 2a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN305066.1 and BC002502.2. On Jan 4, 2014 this sequence version replaced NM_198426.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.295631.1, SRR1163657.477607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267753, SAMN03267755 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940818.1
CDS	164..832
Translation	MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD

Target ORF information:

RefSeq Version	NM_198426.2
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198426.2

ORF Insert Sequence:

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AACCTCCCCT CAACTGGGGG CTCGCTTAGT GTGGCTGCTG GTGGGAAAAA AGCAGAGGCC 
GCAGCCTCAG CCCTAGCTGA TGCTGATGCA GACCTGGAGG AACGGCTTAA GAACCTGCGG 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP2A ( XM_005258746.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005258803.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu52168
Clone ID Related Accession (Same CDS sequence)	XM_005258746.2 , XM_005258746.3 , XM_005258747.3
Accession Version	XM_005258746.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 2a isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005258746.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AGTGAGTGCT CCAAATCCTG GACCCCATTT CCCACCCAAG GCCCAGCCAC AGCTCCAAGC 
CCTCCCTTTC CCTGCATTAC TCCCCTCCGC TGCCTGACCC CACCTGCTCA AACCCCCACT 
TTCTCTGCAG ACCTCCCCTC AACTGGGGGC TCGCTTAGTG TGGCTGCTGG TGGGAAAAAA 
GCAGAGGCCG CAGCCTCAGC CCTAGCTGAT GCTGATGCAG ACCTGGAGGA ACGGCTTAAG 
AACCTGCGGA GGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258803.1
CDS	662..1459
Translation	MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSSECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD

Target ORF information:

RefSeq Version	XM_005258746.2
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258746.2

ORF Insert Sequence:

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AGTGAGTGCT CCAAATCCTG GACCCCATTT CCCACCCAAG GCCCAGCCAC AGCTCCAAGC 
CCTCCCTTTC CCTGCATTAC TCCCCTCCGC TGCCTGACCC CACCTGCTCA AACCCCCACT 
TTCTCTGCAG ACCTCCCCTC AACTGGGGGC TCGCTTAGTG TGGCTGCTGG TGGGAAAAAA 
GCAGAGGCCG CAGCCTCAGC CCTAGCTGAT GCTGATGCAG ACCTGGAGGA ACGGCTTAAG 
AACCTGCGGA GGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP2A ( XM_005258746.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005258803.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu52168
Clone ID Related Accession (Same CDS sequence)	XM_005258746.2 , XM_005258746.3 , XM_005258747.3
Accession Version	XM_005258746.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 2a isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005258746.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AGTGAGTGCT CCAAATCCTG GACCCCATTT CCCACCCAAG GCCCAGCCAC AGCTCCAAGC 
CCTCCCTTTC CCTGCATTAC TCCCCTCCGC TGCCTGACCC CACCTGCTCA AACCCCCACT 
TTCTCTGCAG ACCTCCCCTC AACTGGGGGC TCGCTTAGTG TGGCTGCTGG TGGGAAAAAA 
GCAGAGGCCG CAGCCTCAGC CCTAGCTGAT GCTGATGCAG ACCTGGAGGA ACGGCTTAAG 
AACCTGCGGA GGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258803.1
CDS	143..940
Translation	MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSSECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD

Target ORF information:

RefSeq Version	XM_005258746.3
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258746.3

ORF Insert Sequence:

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AGTGAGTGCT CCAAATCCTG GACCCCATTT CCCACCCAAG GCCCAGCCAC AGCTCCAAGC 
CCTCCCTTTC CCTGCATTAC TCCCCTCCGC TGCCTGACCC CACCTGCTCA AACCCCCACT 
TTCTCTGCAG ACCTCCCCTC AACTGGGGGC TCGCTTAGTG TGGCTGCTGG TGGGAAAAAA 
GCAGAGGCCG CAGCCTCAGC CCTAGCTGAT GCTGATGCAG ACCTGGAGGA ACGGCTTAAG 
AACCTGCGGA GGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP2A ( XM_005258747.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005258804.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu52168
Clone ID Related Accession (Same CDS sequence)	XM_005258746.2 , XM_005258746.3 , XM_005258747.3
Accession Version	XM_005258747.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 2a isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005258747.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AGTGAGTGCT CCAAATCCTG GACCCCATTT CCCACCCAAG GCCCAGCCAC AGCTCCAAGC 
CCTCCCTTTC CCTGCATTAC TCCCCTCCGC TGCCTGACCC CACCTGCTCA AACCCCCACT 
TTCTCTGCAG ACCTCCCCTC AACTGGGGGC TCGCTTAGTG TGGCTGCTGG TGGGAAAAAA 
GCAGAGGCCG CAGCCTCAGC CCTAGCTGAT GCTGATGCAG ACCTGGAGGA ACGGCTTAAG 
AACCTGCGGA GGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258804.1
CDS	785..1582
Translation	MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSSECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD

Target ORF information:

RefSeq Version	XM_005258747.3
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258747.3

ORF Insert Sequence:

ATGGACCTAT TGTTCGGGCG CCGGAAGACG CCAGAGGAGC TACTGCGGCA GAACCAGAGG 
GCCCTGAACC GTGCCATGCG GGAGCTGGAC CGCGAGCGAC AGAAACTAGA GACCCAGGAG 
AAGAAAATCA TTGCAGACAT TAAGAAGATG GCCAAGCAAG GCCAGATGGA TGCTGTTCGC 
ATCATGGCAA AAGACTTGGT GCGCACCCGG CGCTATGTGC GCAAGTTTGT ATTGATGCGG 
GCCAACATCC AGGCTGTGTC CCTCAAGATC CAGACACTCA AGTCCAACAA CTCGATGGCA 
CAAGCCATGA AGGGTGTCAC CAAGGCCATG GGCACCATGA ACAGACAGCT GAAGTTGCCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAG CGGCAGGCAG AGATCATGGA TATGAAGGAG 
GAGATGATGA ATGATGCCAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTGG TGTCCCAGGT TCTGGATGAG CTGGGACTTA GCCTAACAGA TGAGCTGTCG 
AGTGAGTGCT CCAAATCCTG GACCCCATTT CCCACCCAAG GCCCAGCCAC AGCTCCAAGC 
CCTCCCTTTC CCTGCATTAC TCCCCTCCGC TGCCTGACCC CACCTGCTCA AACCCCCACT 
TTCTCTGCAG ACCTCCCCTC AACTGGGGGC TCGCTTAGTG TGGCTGCTGG TGGGAAAAAA 
GCAGAGGCCG CAGCCTCAGC CCTAGCTGAT GCTGATGCAG ACCTGGAGGA ACGGCTTAAG 
AACCTGCGGA GGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells.
Proceedings of the National Academy of Sciences of the United States of America114(11)E2166-E2175(2017 Mar)
Gu M,LaJoie D,Chen OS,von Appen A,Ladinsky MS,Redd MJ,Nikolova L,Bjorkman PJ,Sundquist WI,Ullman KS,Frost A

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Nature522(7555)231-5(2015 Jun)
Vietri M,Schink KO,Campsteijn C,Wegner CS,Schultz SW,Christ L,Thoresen SB,Brech A,Raiborg C,Stenmark H

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.
eLife3(2014 May)
Cashikar AG,Shim S,Roth R,Maldazys MR,Heuser JE,Hanson PI

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CHMP2A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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