INVS cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	INVS
Entrez Gene ID	27130
Full Name	inversin
Synonyms	INV,NPH2,NPHP2
General protein information	Preferred Names inversin Names inversin inversion of embryo turning homolog inversion of embryonic turning nephrocystin-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q31.1
Summary	This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012].
Disorder MIM:	243305
Disorder Html:	Nephronophthisis 2, infantile, 602088 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001318382.1	NP_001305311.1	inversin isoform d
NM_014425.5	NP_055240.2	inversin isoform a
NM_014425.4	NP_055240.2	inversin isoform a
NM_001318381.1	NP_001305310.1	inversin isoform c

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Invs	NP_034699.3
Canis lupus familiaris (dog)	INVS	NP_001003361.1
Caenorhabditis elegans (roundworm)	mlt-4	NP_507912.2
Homo sapiens (human)	INVS	NP_055240.2
Pan troglodytes (chimpanzee)	INVS	XP_528516.2
	INVS	XP_002800074.1
Gallus gallus (chicken)	INVS	NP_989882.1
Bos taurus (cattle)	INVS	NP_001071451.1
Rattus norvegicus (Norway rat)	Invs	NP_001101402.1
Danio rerio (zebrafish)	invs	NP_694502.1

Gene Ontology
Bibliography

Related articles in PubMed

Inversin correlates with the malignant phenotype of non-small cell lung cancer and promotes the invasiveness of lung cancer cells.
Jiang GY, Zhang Y, Zhang XP, Lin XY, Yu JH, Wang EH
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(6)1010428317691177(2017 Jun)

Phosphorylation-dependent Akt-Inversin interaction at the basal body of primary cilia.
Suizu F, Hirata N, Kimura K, Edamura T, Tanaka T, Ishigaki S, Donia T, Noguchi H, Iwanaga T, Noguchi M
The EMBO journal35(12)1346-63(2016 06)

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmst?dter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS
Nature genetics45(8)951-6(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Collectively, these results indicated that inversin might promote the tumorigenicity of lung cancer cells and serve as a novel therapeutic target of non-small cell lung cancer.
Title: Inversin correlates with the malignant phenotype of non-small cell lung cancer and promotes the invasiveness of lung cancer cells.

Akt phosphorylates inversin at amino acids 864-866 that are required not only for Akt interaction, but also for inversin dimerization.
Title: Phosphorylation-dependent Akt-Inversin interaction at the basal body of primary cilia.

ANKS6 as a new NPHP family member that assembles a distinct module of nephronophthisis-associated proteins, encompassing NEK8, INVS and NPHP3.
Title: ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.

Truncating mutations in NPHP2 gene is associated with nephronophthisis-related ciliopathy.
Title: Identification of 99 novel mutations in a worldwide cohort of 1,056 patients with a nephronophthisis-related ciliopathy.

Observational study of gene-disease association. (HuGE Navigator)
Title: Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy.

The following INVS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INVS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27638	NM_014425.5 Latest version!	Homo sapiens inversin (INVS), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu67083	NM_001318382.1 Latest version!	Homo sapiens inversin (INVS), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu101991	NM_001318381.1 Latest version!	Homo sapiens inversin (INVS), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OHu27638	NM_014425.4	Homo sapiens inversin (INVS), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

INVS ( NM_014425.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_055240.2 Homo sapiens inversin (INVS), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27638
Clone ID Related Accession (Same CDS sequence)	NM_014425.5 , NM_014425.4
Accession Version	NM_014425.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3198bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	inversin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB217652.1, BC111761.1, AL356798.18, BC063847.1 and AL445214.7. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_014425.4. Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF039217.2, BC111761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000262457.7/ ENSP00000262457.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACAAGT CAGAGAACCT GCTGTTTGCT GGTTCATCAT TAGCATCACA AGTCCATGCT 
GCTGCCGTTA ATGGAGATAA GGGTGCTCTA CAGAGGCTCA TCGTAGGAAA CTCTGCTCTT 
AAAGACAAAG AAGATCAGTT TGGGAGAACA CCACTTATGT ATTGCGTGTT GGCTGACAGA 
TTGGATTGTG CAGATGCTCT TCTGAAGGCA GGAGCAGATG TGAATAAAAC TGACCATAGC 
CAGAGAACAG CCCTCCATCT TGCAGCCCAG AAGGGAAATT ATCGTTTCAT GAAACTCTTA 
CTTACACGCA GAGCAAACTG GATGCAAAAG GATCTGGAAG AGATGACTCC TTTGCACTTG 
ACCACCCGGC ACAGGAGCCC TAAGTGTTTG GCACTTCTGC TGAAGTTTAT GGCACCAGGA 
GAAGTGGATA CACAGGATAA AAACAAGCAA ACAGCTCTGC ATTGGAGTGC CTACTACAAT 
AACCCTGAGC ATGTGAAGCT GCTCATCAAG CATGATTCTA ACATTGGGAT TCCTGATGTT 
GAAGGCAAGA TCCCACTTCA CTGGGCAGCC AACCATAAAG ATCCAAGTGC TGTTCACACA 
GTGAGATGCA TTCTGGATGC TGCTCCAACA GAGTCTTTAC TGAACTGGCA AGACTACGAG 
GGTCGAACTC CTCTTCACTT TGCAGTTGCT GATGGGAATG TGACCGTGGT TGATGTCTTG 
ACCTCATATG AAAGCTGCAA TATAACGTCT TATGATAACT TATTTCGAAC CCCACTGCAC 
TGGGCAGCTT TATTAGGCCA TGCACAGATT GTCCATCTCC TTTTAGAAAG AAATAAGTCT 
GGAACTATCC CATCTGACAG CCAAGGAGCC ACACCTTTGC ACTATGCTGC TCAGAGTAAC 
TTTGCTGAAA CGGTTAAAGT GTTTTTAAAA CATCCTTCAG TGAAAGATGA TTCAGACCTG 
GAAGGAAGAA CATCCTTTAT GTGGGCAGCT GGCAAAGGCA GTGATGATGT CCTTAGAACT 
ATGCTGAGCT TAAAATCGGA CATAGATATT AACATGGCTG ACAAATATGG AGGTACAGCT 
TTGCATGCTG CTGCTCTTTC TGGCCATGTC AGCACCGTGA AGTTATTACT GGAAAATAAT 
GCTCAAGTAG ATGCTACTGA TGTTATGAAA CATACTCCAC TTTTCCGAGC CTGTGAGATG 
GGACACAAAG ATGTGATTCA GACACTCATT AAAGGTGGAG CAAGGGTAGA TCTAGTTGAC 
CAAGATGGAC ATTCTCTTCT ACATTGGGCA GCACTGGGAG GAAATGCTGA TGTTTGCCAG 
ATATTAATAG AAAATAAGAT CAATCCAAAT GTCCAGGATT ATGCAGGAAG AACCCCTTTG 
CAGTGTGCAG CATATGGAGG CTATATCAAC TGCATGGCAG TTCTCATGGA AAACAATGCA 
GACCCTAACA TTCAAGACAA AGAGGGAAGA ACAGCTTTGC ATTGGTCCTG CAACAATGGA 
TACCTTGATG CCATTAAATT ACTGCTAGAC TTTGCTGCTT TCCCTAATCA GATGGAAAAC 
AATGAAGAGA GATACACACC CCTTGATTAT GCTTTGCTTG GTGAGCGCCA TGAAGTGATC 
CAGTTCATGT TGGAGCACGG TGCCCTGTCC ATCGCAGCCA TACAAGACAT CGCCGCCTTC 
AAAATCCAAG CTGTCTACAA AGGGTACAAG GTCAGAAAAG CCTTCCGAGA CAGGAAAAAT 
CTCCTCATGA AGCATGAACA GTTGAGAAAA GATGCTGCTG CCAAAAAGCG AGAGGAAGAA 
AACAAACGAA AAGAGGCAGA ACAGCAAAAA GGAAGGCGGA GCCCAGATTC CTGCAGACCC 
CAGGCCCTTC CCTGTCTGCC TAGCACCCAG GATGTGCCCA GCAGGCAGAG CCGGGCCCCC 
AGCAAGCAGC CTCCTGCTGG CAACGTGGCC CAAGGCCCTG AGCCAAGAGA CAGCAGAGGA 
TCTCCAGGAG GGTCTCTAGG CGGAGCCCTC CAGAAGGAGC AGCATGTTTC CTCAGATTTG 
CAGGGAACAA ACTCCAGAAG GCCAAATGAA ACAGCCAGAG AACATTCTAA AGGCCAATCT 
GCTTGTGTCC ACTTCAGACC CAATGAAGGC AGTGATGGAA GCAGGCATCC AGGAGTTCCC 
TCTGTTGAGA AGTCCAGAGG TGAGACAGCT GGCGATGAGC GGTGTGCAAA GGGGAAAGGC 
TTCGTGAAGC AGCCCTCCTG TATCAGGGTG GCTGGGCCTG ATGAGAAAGG AGAGGACTCC 
AGGCGGGCAG CTGCAAGCCT TCCACCGCAC GATAGCCACT GGAAGCCCAG CAGGCGGCAT 
GACACAGAAC CCAAGGCCAA ATGTGCCCCC CAGAAAAGGC GCACTCAAGA GCTCAGAGGA 
GGAAGGTGCT CTCCGGCTGG TTCTAGCCGC CCTGGCAGTG CCCGGGGGGA GGCGGTCCAT 
GCTGGGCAGA ATCCTCCCCA CCATCGTACA CCAAGAAACA AAGTGACACA AGCCAAGCTC 
ACAGGAGGGC TCTATTCACA TTTGCCACAG AGCACAGAGG AGTTGAGGTC AGGAGCTAGG 
AGGCTGGAGA CATCTACCCT GTCCGAGGAC TTTCAGGTAT CTAAGGAGAC TGATCCAGCA 
CCTGGTCCCC TCTCTGGGCA GAGTGTGAAT ATTGACCTTC TCCCCGTAGA GCTCCGACTG 
CAGATAATTC AGAGAGAACG AAGGAGGAAG GAGCTGTTTC GCAAAAAGAA CAAGGCAGCA 
GCAGTCATCC AGCGCGCCTG GCGAAGCTAC CAGCTCAGGA AGCACCTGTC CCACCTTCGG 
CATATGAAGC AGCTTGGAGC TGGAGATGTG GACAGATGGA GGCAAGAGTC TACAGCATTG 
CTCCTCCAGG TTTGGAGGAA GGAACTGGAA CTAAAATTCC CCCAAACCAC TGCAGTAAGC 
AAGGCCCCCA AGAGTCCATC CAAGGGCACC TCAGGCACAA AGTCCACCAA GCACTCAGTG 
CTTAAGCAAA TCTATGGTTG TTCTCACGAA GGGAAAATAC ATCATCCTAC AAGATCTGTA 
AAAGCCTCTT CTGTGCTGCG TCTCAACTCA GTGAGCAACC TACAGTGTAT ACATCTCCTT 
GAGAACAGTG GAAGATCAAA GAACTTTTCT TATAACCTGC AATCAGCTAC TCAGCCAAAA 
AACAAAACAA AACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055240.2
CDS	199..3396
Translation	MNKSENLLFAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSCRPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSPGGSLGGALQKEQHVSSDLQGTNSRRPNETAREHSKGQSACVHFRPNEGSDGSRHPGVPSVEKSRGETAGDERCAKGKGFVKQPSCIRVAGPDEKGEDSRRAAASLPPHDSHWKPSRRHDTEPKAKCAPQKRRTQELRGGRCSPAGSSRPGSARGEAVHAGQNPPHHRTPRNKVTQAKLTGGLYSHLPQSTEELRSGARRLETSTLSEDFQVSKETDPAPGPLSGQSVNIDLLPVELRLQIIQRERRRKELFRKKNKAAAVIQRAWRSYQLRKHLSHLRHMKQLGAGDVDRWRQESTALLLQVWRKELELKFPQTTAVSKAPKSPSKGTSGTKSTKHSVLKQIYGCSHEGKIHHPTRSVKASSVLRLNSVSNLQCIHLLENSGRSKNFSYNLQSATQPKNKTKP

Target ORF information:

RefSeq Version	NM_014425.5
Organism	Homo sapiens(human)
Definition	Homo sapiens inversin (INVS), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014425.5

ORF Insert Sequence:

ATGAACAAGT CAGAGAACCT GCTGTTTGCT GGTTCATCAT TAGCATCACA AGTCCATGCT 
GCTGCCGTTA ATGGAGATAA GGGTGCTCTA CAGAGGCTCA TCGTAGGAAA CTCTGCTCTT 
AAAGACAAAG AAGATCAGTT TGGGAGAACA CCACTTATGT ATTGCGTGTT GGCTGACAGA 
TTGGATTGTG CAGATGCTCT TCTGAAGGCA GGAGCAGATG TGAATAAAAC TGACCATAGC 
CAGAGAACAG CCCTCCATCT TGCAGCCCAG AAGGGAAATT ATCGTTTCAT GAAACTCTTA 
CTTACACGCA GAGCAAACTG GATGCAAAAG GATCTGGAAG AGATGACTCC TTTGCACTTG 
ACCACCCGGC ACAGGAGCCC TAAGTGTTTG GCACTTCTGC TGAAGTTTAT GGCACCAGGA 
GAAGTGGATA CACAGGATAA AAACAAGCAA ACAGCTCTGC ATTGGAGTGC CTACTACAAT 
AACCCTGAGC ATGTGAAGCT GCTCATCAAG CATGATTCTA ACATTGGGAT TCCTGATGTT 
GAAGGCAAGA TCCCACTTCA CTGGGCAGCC AACCATAAAG ATCCAAGTGC TGTTCACACA 
GTGAGATGCA TTCTGGATGC TGCTCCAACA GAGTCTTTAC TGAACTGGCA AGACTACGAG 
GGTCGAACTC CTCTTCACTT TGCAGTTGCT GATGGGAATG TGACCGTGGT TGATGTCTTG 
ACCTCATATG AAAGCTGCAA TATAACGTCT TATGATAACT TATTTCGAAC CCCACTGCAC 
TGGGCAGCTT TATTAGGCCA TGCACAGATT GTCCATCTCC TTTTAGAAAG AAATAAGTCT 
GGAACTATCC CATCTGACAG CCAAGGAGCC ACACCTTTGC ACTATGCTGC TCAGAGTAAC 
TTTGCTGAAA CGGTTAAAGT GTTTTTAAAA CATCCTTCAG TGAAAGATGA TTCAGACCTG 
GAAGGAAGAA CATCCTTTAT GTGGGCAGCT GGCAAAGGCA GTGATGATGT CCTTAGAACT 
ATGCTGAGCT TAAAATCGGA CATAGATATT AACATGGCTG ACAAATATGG AGGTACAGCT 
TTGCATGCTG CTGCTCTTTC TGGCCATGTC AGCACCGTGA AGTTATTACT GGAAAATAAT 
GCTCAAGTAG ATGCTACTGA TGTTATGAAA CATACTCCAC TTTTCCGAGC CTGTGAGATG 
GGACACAAAG ATGTGATTCA GACACTCATT AAAGGTGGAG CAAGGGTAGA TCTAGTTGAC 
CAAGATGGAC ATTCTCTTCT ACATTGGGCA GCACTGGGAG GAAATGCTGA TGTTTGCCAG 
ATATTAATAG AAAATAAGAT CAATCCAAAT GTCCAGGATT ATGCAGGAAG AACCCCTTTG 
CAGTGTGCAG CATATGGAGG CTATATCAAC TGCATGGCAG TTCTCATGGA AAACAATGCA 
GACCCTAACA TTCAAGACAA AGAGGGAAGA ACAGCTTTGC ATTGGTCCTG CAACAATGGA 
TACCTTGATG CCATTAAATT ACTGCTAGAC TTTGCTGCTT TCCCTAATCA GATGGAAAAC 
AATGAAGAGA GATACACACC CCTTGATTAT GCTTTGCTTG GTGAGCGCCA TGAAGTGATC 
CAGTTCATGT TGGAGCACGG TGCCCTGTCC ATCGCAGCCA TACAAGACAT CGCCGCCTTC 
AAAATCCAAG CTGTCTACAA AGGGTACAAG GTCAGAAAAG CCTTCCGAGA CAGGAAAAAT 
CTCCTCATGA AGCATGAACA GTTGAGAAAA GATGCTGCTG CCAAAAAGCG AGAGGAAGAA 
AACAAACGAA AAGAGGCAGA ACAGCAAAAA GGAAGGCGGA GCCCAGATTC CTGCAGACCC 
CAGGCCCTTC CCTGTCTGCC TAGCACCCAG GATGTGCCCA GCAGGCAGAG CCGGGCCCCC 
AGCAAGCAGC CTCCTGCTGG CAACGTGGCC CAAGGCCCTG AGCCAAGAGA CAGCAGAGGA 
TCTCCAGGAG GGTCTCTAGG CGGAGCCCTC CAGAAGGAGC AGCATGTTTC CTCAGATTTG 
CAGGGAACAA ACTCCAGAAG GCCAAATGAA ACAGCCAGAG AACATTCTAA AGGCCAATCT 
GCTTGTGTCC ACTTCAGACC CAATGAAGGC AGTGATGGAA GCAGGCATCC AGGAGTTCCC 
TCTGTTGAGA AGTCCAGAGG TGAGACAGCT GGCGATGAGC GGTGTGCAAA GGGGAAAGGC 
TTCGTGAAGC AGCCCTCCTG TATCAGGGTG GCTGGGCCTG ATGAGAAAGG AGAGGACTCC 
AGGCGGGCAG CTGCAAGCCT TCCACCGCAC GATAGCCACT GGAAGCCCAG CAGGCGGCAT 
GACACAGAAC CCAAGGCCAA ATGTGCCCCC CAGAAAAGGC GCACTCAAGA GCTCAGAGGA 
GGAAGGTGCT CTCCGGCTGG TTCTAGCCGC CCTGGCAGTG CCCGGGGGGA GGCGGTCCAT 
GCTGGGCAGA ATCCTCCCCA CCATCGTACA CCAAGAAACA AAGTGACACA AGCCAAGCTC 
ACAGGAGGGC TCTATTCACA TTTGCCACAG AGCACAGAGG AGTTGAGGTC AGGAGCTAGG 
AGGCTGGAGA CATCTACCCT GTCCGAGGAC TTTCAGGTAT CTAAGGAGAC TGATCCAGCA 
CCTGGTCCCC TCTCTGGGCA GAGTGTGAAT ATTGACCTTC TCCCCGTAGA GCTCCGACTG 
CAGATAATTC AGAGAGAACG AAGGAGGAAG GAGCTGTTTC GCAAAAAGAA CAAGGCAGCA 
GCAGTCATCC AGCGCGCCTG GCGAAGCTAC CAGCTCAGGA AGCACCTGTC CCACCTTCGG 
CATATGAAGC AGCTTGGAGC TGGAGATGTG GACAGATGGA GGCAAGAGTC TACAGCATTG 
CTCCTCCAGG TTTGGAGGAA GGAACTGGAA CTAAAATTCC CCCAAACCAC TGCAGTAAGC 
AAGGCCCCCA AGAGTCCATC CAAGGGCACC TCAGGCACAA AGTCCACCAA GCACTCAGTG 
CTTAAGCAAA TCTATGGTTG TTCTCACGAA GGGAAAATAC ATCATCCTAC AAGATCTGTA 
AAAGCCTCTT CTGTGCTGCG TCTCAACTCA GTGAGCAACC TACAGTGTAT ACATCTCCTT 
GAGAACAGTG GAAGATCAAA GAACTTTTCT TATAACCTGC AATCAGCTAC TCAGCCAAAA 
AACAAAACAA AACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INVS ( NM_014425.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055240.2 Homo sapiens inversin (INVS), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27638
Clone ID Related Accession (Same CDS sequence)	NM_014425.5 , NM_014425.4
Accession Version	NM_014425.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3198bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	inversin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB217652.1, BC111761.1, AL356798.18, BC063847.1 and AL445214.7. This sequence is a reference standard in the RefSeqGene project. On Jan 6, 2016 this sequence version replaced NM_014425.3. Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF039217.2, BC111761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAGT CAGAGAACCT GCTGTTTGCT GGTTCATCAT TAGCATCACA AGTCCATGCT 
GCTGCCGTTA ATGGAGATAA GGGTGCTCTA CAGAGGCTCA TCGTAGGAAA CTCTGCTCTT 
AAAGACAAAG AAGATCAGTT TGGGAGAACA CCACTTATGT ATTGCGTGTT GGCTGACAGA 
TTGGATTGTG CAGATGCTCT TCTGAAGGCA GGAGCAGATG TGAATAAAAC TGACCATAGC 
CAGAGAACAG CCCTCCATCT TGCAGCCCAG AAGGGAAATT ATCGTTTCAT GAAACTCTTA 
CTTACACGCA GAGCAAACTG GATGCAAAAG GATCTGGAAG AGATGACTCC TTTGCACTTG 
ACCACCCGGC ACAGGAGCCC TAAGTGTTTG GCACTTCTGC TGAAGTTTAT GGCACCAGGA 
GAAGTGGATA CACAGGATAA AAACAAGCAA ACAGCTCTGC ATTGGAGTGC CTACTACAAT 
AACCCTGAGC ATGTGAAGCT GCTCATCAAG CATGATTCTA ACATTGGGAT TCCTGATGTT 
GAAGGCAAGA TCCCACTTCA CTGGGCAGCC AACCATAAAG ATCCAAGTGC TGTTCACACA 
GTGAGATGCA TTCTGGATGC TGCTCCAACA GAGTCTTTAC TGAACTGGCA AGACTACGAG 
GGTCGAACTC CTCTTCACTT TGCAGTTGCT GATGGGAATG TGACCGTGGT TGATGTCTTG 
ACCTCATATG AAAGCTGCAA TATAACGTCT TATGATAACT TATTTCGAAC CCCACTGCAC 
TGGGCAGCTT TATTAGGCCA TGCACAGATT GTCCATCTCC TTTTAGAAAG AAATAAGTCT 
GGAACTATCC CATCTGACAG CCAAGGAGCC ACACCTTTGC ACTATGCTGC TCAGAGTAAC 
TTTGCTGAAA CGGTTAAAGT GTTTTTAAAA CATCCTTCAG TGAAAGATGA TTCAGACCTG 
GAAGGAAGAA CATCCTTTAT GTGGGCAGCT GGCAAAGGCA GTGATGATGT CCTTAGAACT 
ATGCTGAGCT TAAAATCGGA CATAGATATT AACATGGCTG ACAAATATGG AGGTACAGCT 
TTGCATGCTG CTGCTCTTTC TGGCCATGTC AGCACCGTGA AGTTATTACT GGAAAATAAT 
GCTCAAGTAG ATGCTACTGA TGTTATGAAA CATACTCCAC TTTTCCGAGC CTGTGAGATG 
GGACACAAAG ATGTGATTCA GACACTCATT AAAGGTGGAG CAAGGGTAGA TCTAGTTGAC 
CAAGATGGAC ATTCTCTTCT ACATTGGGCA GCACTGGGAG GAAATGCTGA TGTTTGCCAG 
ATATTAATAG AAAATAAGAT CAATCCAAAT GTCCAGGATT ATGCAGGAAG AACCCCTTTG 
CAGTGTGCAG CATATGGAGG CTATATCAAC TGCATGGCAG TTCTCATGGA AAACAATGCA 
GACCCTAACA TTCAAGACAA AGAGGGAAGA ACAGCTTTGC ATTGGTCCTG CAACAATGGA 
TACCTTGATG CCATTAAATT ACTGCTAGAC TTTGCTGCTT TCCCTAATCA GATGGAAAAC 
AATGAAGAGA GATACACACC CCTTGATTAT GCTTTGCTTG GTGAGCGCCA TGAAGTGATC 
CAGTTCATGT TGGAGCACGG TGCCCTGTCC ATCGCAGCCA TACAAGACAT CGCCGCCTTC 
AAAATCCAAG CTGTCTACAA AGGGTACAAG GTCAGAAAAG CCTTCCGAGA CAGGAAAAAT 
CTCCTCATGA AGCATGAACA GTTGAGAAAA GATGCTGCTG CCAAAAAGCG AGAGGAAGAA 
AACAAACGAA AAGAGGCAGA ACAGCAAAAA GGAAGGCGGA GCCCAGATTC CTGCAGACCC 
CAGGCCCTTC CCTGTCTGCC TAGCACCCAG GATGTGCCCA GCAGGCAGAG CCGGGCCCCC 
AGCAAGCAGC CTCCTGCTGG CAACGTGGCC CAAGGCCCTG AGCCAAGAGA CAGCAGAGGA 
TCTCCAGGAG GGTCTCTAGG CGGAGCCCTC CAGAAGGAGC AGCATGTTTC CTCAGATTTG 
CAGGGAACAA ACTCCAGAAG GCCAAATGAA ACAGCCAGAG AACATTCTAA AGGCCAATCT 
GCTTGTGTCC ACTTCAGACC CAATGAAGGC AGTGATGGAA GCAGGCATCC AGGAGTTCCC 
TCTGTTGAGA AGTCCAGAGG TGAGACAGCT GGCGATGAGC GGTGTGCAAA GGGGAAAGGC 
TTCGTGAAGC AGCCCTCCTG TATCAGGGTG GCTGGGCCTG ATGAGAAAGG AGAGGACTCC 
AGGCGGGCAG CTGCAAGCCT TCCACCGCAC GATAGCCACT GGAAGCCCAG CAGGCGGCAT 
GACACAGAAC CCAAGGCCAA ATGTGCCCCC CAGAAAAGGC GCACTCAAGA GCTCAGAGGA 
GGAAGGTGCT CTCCGGCTGG TTCTAGCCGC CCTGGCAGTG CCCGGGGGGA GGCGGTCCAT 
GCTGGGCAGA ATCCTCCCCA CCATCGTACA CCAAGAAACA AAGTGACACA AGCCAAGCTC 
ACAGGAGGGC TCTATTCACA TTTGCCACAG AGCACAGAGG AGTTGAGGTC AGGAGCTAGG 
AGGCTGGAGA CATCTACCCT GTCCGAGGAC TTTCAGGTAT CTAAGGAGAC TGATCCAGCA 
CCTGGTCCCC TCTCTGGGCA GAGTGTGAAT ATTGACCTTC TCCCCGTAGA GCTCCGACTG 
CAGATAATTC AGAGAGAACG AAGGAGGAAG GAGCTGTTTC GCAAAAAGAA CAAGGCAGCA 
GCAGTCATCC AGCGCGCCTG GCGAAGCTAC CAGCTCAGGA AGCACCTGTC CCACCTTCGG 
CATATGAAGC AGCTTGGAGC TGGAGATGTG GACAGATGGA GGCAAGAGTC TACAGCATTG 
CTCCTCCAGG TTTGGAGGAA GGAACTGGAA CTAAAATTCC CCCAAACCAC TGCAGTAAGC 
AAGGCCCCCA AGAGTCCATC CAAGGGCACC TCAGGCACAA AGTCCACCAA GCACTCAGTG 
CTTAAGCAAA TCTATGGTTG TTCTCACGAA GGGAAAATAC ATCATCCTAC AAGATCTGTA 
AAAGCCTCTT CTGTGCTGCG TCTCAACTCA GTGAGCAACC TACAGTGTAT ACATCTCCTT 
GAGAACAGTG GAAGATCAAA GAACTTTTCT TATAACCTGC AATCAGCTAC TCAGCCAAAA 
AACAAAACAA AACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055240.2
CDS	257..3454
Translation	MNKSENLLFAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSCRPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSPGGSLGGALQKEQHVSSDLQGTNSRRPNETAREHSKGQSACVHFRPNEGSDGSRHPGVPSVEKSRGETAGDERCAKGKGFVKQPSCIRVAGPDEKGEDSRRAAASLPPHDSHWKPSRRHDTEPKAKCAPQKRRTQELRGGRCSPAGSSRPGSARGEAVHAGQNPPHHRTPRNKVTQAKLTGGLYSHLPQSTEELRSGARRLETSTLSEDFQVSKETDPAPGPLSGQSVNIDLLPVELRLQIIQRERRRKELFRKKNKAAAVIQRAWRSYQLRKHLSHLRHMKQLGAGDVDRWRQESTALLLQVWRKELELKFPQTTAVSKAPKSPSKGTSGTKSTKHSVLKQIYGCSHEGKIHHPTRSVKASSVLRLNSVSNLQCIHLLENSGRSKNFSYNLQSATQPKNKTKP

Target ORF information:

RefSeq Version	NM_014425.4
Organism	Homo sapiens(human)
Definition	Homo sapiens inversin (INVS), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014425.4

ORF Insert Sequence:

ATGAACAAGT CAGAGAACCT GCTGTTTGCT GGTTCATCAT TAGCATCACA AGTCCATGCT 
GCTGCCGTTA ATGGAGATAA GGGTGCTCTA CAGAGGCTCA TCGTAGGAAA CTCTGCTCTT 
AAAGACAAAG AAGATCAGTT TGGGAGAACA CCACTTATGT ATTGCGTGTT GGCTGACAGA 
TTGGATTGTG CAGATGCTCT TCTGAAGGCA GGAGCAGATG TGAATAAAAC TGACCATAGC 
CAGAGAACAG CCCTCCATCT TGCAGCCCAG AAGGGAAATT ATCGTTTCAT GAAACTCTTA 
CTTACACGCA GAGCAAACTG GATGCAAAAG GATCTGGAAG AGATGACTCC TTTGCACTTG 
ACCACCCGGC ACAGGAGCCC TAAGTGTTTG GCACTTCTGC TGAAGTTTAT GGCACCAGGA 
GAAGTGGATA CACAGGATAA AAACAAGCAA ACAGCTCTGC ATTGGAGTGC CTACTACAAT 
AACCCTGAGC ATGTGAAGCT GCTCATCAAG CATGATTCTA ACATTGGGAT TCCTGATGTT 
GAAGGCAAGA TCCCACTTCA CTGGGCAGCC AACCATAAAG ATCCAAGTGC TGTTCACACA 
GTGAGATGCA TTCTGGATGC TGCTCCAACA GAGTCTTTAC TGAACTGGCA AGACTACGAG 
GGTCGAACTC CTCTTCACTT TGCAGTTGCT GATGGGAATG TGACCGTGGT TGATGTCTTG 
ACCTCATATG AAAGCTGCAA TATAACGTCT TATGATAACT TATTTCGAAC CCCACTGCAC 
TGGGCAGCTT TATTAGGCCA TGCACAGATT GTCCATCTCC TTTTAGAAAG AAATAAGTCT 
GGAACTATCC CATCTGACAG CCAAGGAGCC ACACCTTTGC ACTATGCTGC TCAGAGTAAC 
TTTGCTGAAA CGGTTAAAGT GTTTTTAAAA CATCCTTCAG TGAAAGATGA TTCAGACCTG 
GAAGGAAGAA CATCCTTTAT GTGGGCAGCT GGCAAAGGCA GTGATGATGT CCTTAGAACT 
ATGCTGAGCT TAAAATCGGA CATAGATATT AACATGGCTG ACAAATATGG AGGTACAGCT 
TTGCATGCTG CTGCTCTTTC TGGCCATGTC AGCACCGTGA AGTTATTACT GGAAAATAAT 
GCTCAAGTAG ATGCTACTGA TGTTATGAAA CATACTCCAC TTTTCCGAGC CTGTGAGATG 
GGACACAAAG ATGTGATTCA GACACTCATT AAAGGTGGAG CAAGGGTAGA TCTAGTTGAC 
CAAGATGGAC ATTCTCTTCT ACATTGGGCA GCACTGGGAG GAAATGCTGA TGTTTGCCAG 
ATATTAATAG AAAATAAGAT CAATCCAAAT GTCCAGGATT ATGCAGGAAG AACCCCTTTG 
CAGTGTGCAG CATATGGAGG CTATATCAAC TGCATGGCAG TTCTCATGGA AAACAATGCA 
GACCCTAACA TTCAAGACAA AGAGGGAAGA ACAGCTTTGC ATTGGTCCTG CAACAATGGA 
TACCTTGATG CCATTAAATT ACTGCTAGAC TTTGCTGCTT TCCCTAATCA GATGGAAAAC 
AATGAAGAGA GATACACACC CCTTGATTAT GCTTTGCTTG GTGAGCGCCA TGAAGTGATC 
CAGTTCATGT TGGAGCACGG TGCCCTGTCC ATCGCAGCCA TACAAGACAT CGCCGCCTTC 
AAAATCCAAG CTGTCTACAA AGGGTACAAG GTCAGAAAAG CCTTCCGAGA CAGGAAAAAT 
CTCCTCATGA AGCATGAACA GTTGAGAAAA GATGCTGCTG CCAAAAAGCG AGAGGAAGAA 
AACAAACGAA AAGAGGCAGA ACAGCAAAAA GGAAGGCGGA GCCCAGATTC CTGCAGACCC 
CAGGCCCTTC CCTGTCTGCC TAGCACCCAG GATGTGCCCA GCAGGCAGAG CCGGGCCCCC 
AGCAAGCAGC CTCCTGCTGG CAACGTGGCC CAAGGCCCTG AGCCAAGAGA CAGCAGAGGA 
TCTCCAGGAG GGTCTCTAGG CGGAGCCCTC CAGAAGGAGC AGCATGTTTC CTCAGATTTG 
CAGGGAACAA ACTCCAGAAG GCCAAATGAA ACAGCCAGAG AACATTCTAA AGGCCAATCT 
GCTTGTGTCC ACTTCAGACC CAATGAAGGC AGTGATGGAA GCAGGCATCC AGGAGTTCCC 
TCTGTTGAGA AGTCCAGAGG TGAGACAGCT GGCGATGAGC GGTGTGCAAA GGGGAAAGGC 
TTCGTGAAGC AGCCCTCCTG TATCAGGGTG GCTGGGCCTG ATGAGAAAGG AGAGGACTCC 
AGGCGGGCAG CTGCAAGCCT TCCACCGCAC GATAGCCACT GGAAGCCCAG CAGGCGGCAT 
GACACAGAAC CCAAGGCCAA ATGTGCCCCC CAGAAAAGGC GCACTCAAGA GCTCAGAGGA 
GGAAGGTGCT CTCCGGCTGG TTCTAGCCGC CCTGGCAGTG CCCGGGGGGA GGCGGTCCAT 
GCTGGGCAGA ATCCTCCCCA CCATCGTACA CCAAGAAACA AAGTGACACA AGCCAAGCTC 
ACAGGAGGGC TCTATTCACA TTTGCCACAG AGCACAGAGG AGTTGAGGTC AGGAGCTAGG 
AGGCTGGAGA CATCTACCCT GTCCGAGGAC TTTCAGGTAT CTAAGGAGAC TGATCCAGCA 
CCTGGTCCCC TCTCTGGGCA GAGTGTGAAT ATTGACCTTC TCCCCGTAGA GCTCCGACTG 
CAGATAATTC AGAGAGAACG AAGGAGGAAG GAGCTGTTTC GCAAAAAGAA CAAGGCAGCA 
GCAGTCATCC AGCGCGCCTG GCGAAGCTAC CAGCTCAGGA AGCACCTGTC CCACCTTCGG 
CATATGAAGC AGCTTGGAGC TGGAGATGTG GACAGATGGA GGCAAGAGTC TACAGCATTG 
CTCCTCCAGG TTTGGAGGAA GGAACTGGAA CTAAAATTCC CCCAAACCAC TGCAGTAAGC 
AAGGCCCCCA AGAGTCCATC CAAGGGCACC TCAGGCACAA AGTCCACCAA GCACTCAGTG 
CTTAAGCAAA TCTATGGTTG TTCTCACGAA GGGAAAATAC ATCATCCTAC AAGATCTGTA 
AAAGCCTCTT CTGTGCTGCG TCTCAACTCA GTGAGCAACC TACAGTGTAT ACATCTCCTT 
GAGAACAGTG GAAGATCAAA GAACTTTTCT TATAACCTGC AATCAGCTAC TCAGCCAAAA 
AACAAAACAA AACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INVS ( NM_001318382.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305311.1 Homo sapiens inversin (INVS), transcript variant 5, mRNA.

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CloneID	OHu67083
Clone ID Related Accession (Same CDS sequence)	NM_001318382.1
Accession Version	NM_001318382.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Homo sapiens(human)
Product	inversin isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB217652.1, AK312795.1, BC063847.1 and AL445214.7. On Jan 6, 2016 this sequence version replaced XM_011518543.1. Transcript Variant: This variant (5) uses an alternate splice site in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (d) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK312795.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGGCAG CTGGCAAAGG CAGTGATGAT GTCCTTAGAA CTATGCTGAG CTTAAAATCG 
GACATAGATA TTAACATGGC TGACAAATAT GGAGGTACAG CTTTGCATGC TGCTGCTCTT 
TCTGGCCATG TCAGCACCGT GAAGTTATTA CTGGAAAATA ATGCTCAAGT AGATGCTACT 
GATGTTATGA AACATACTCC ACTTTTCCGA GCCTGTGAGA TGGGACACAA AGATGTGATT 
CAGACACTCA TTAAAGGTGG AGCAAGGGTA GATCTAGTTG ACCAAGATGG ACATTCTCTT 
CTACATTGGG CAGCACTGGG AGGAAATGCT GATGTTTGCC AGATATTAAT AGAAAATAAG 
ATCAATCCAA ATGTCCAGGA TTATGCAGGA AGAACCCCTT TGCAGTGTGC AGCATATGGA 
GGCTATATCA ACTGCATGGC AGTTCTCATG GAAAACAATG CAGACCCTAA CATTCAAGAC 
AAAGAGGGAA GAACAGCTTT GCATTGGTCC TGCAACAATG GATACCTTGA TGCCATTAAA 
TTACTGCTAG ACTTTGCTGC TTTCCCTAAT CAGATGGAAA ACAATGAAGA GAGATACACA 
CCCCTTGATT ATGCTTTGCT TGGTGAGCGC CATGAAGTGA TCCAGTTCAT GTTGGAGCAC 
GGTGCCCTGT CCATCGCAGC CATACAAGAC ATCGCCGCCT TCAAAATCCA AGCTGTCTAC 
AAAGGGTACA AGGTCAGAAA AGCCTTCCGA GACAGGAAAA ATCTCCTCAT GAAGCATGAA 
CAGTTGAGAA AAGATGCTGC TGCCAAAAAG CGAGAGGAAG AAAACAAACG AAAAGAGGCA 
GAACAGCAAA AAGGAAGGCG GAGCCCAGAT TCCTGCAGAC CCCAGGCCCT TCCCTGTCTG 
CCTAGCACCC AGGATGTGCC CAGCAGGCAG AGCCGGGCCC CCAGCAAGCA GCCTCCTGCT 
GGCAACGTGG CCCAAGGCCC TGAGCCAAGA GACAGCAGAG GATCTCCAGG AGGGTCTCTA 
GGCGGAGCCC TCCAGAAGGA GCAGCATGTT TCCTCAGATT TGCAGGGAAC AAACTCCAGA 
AGGCCAAATG AAACAGCCAG AGAACATTCT AAAGGCCAAT CTGCTTGTGT CCACTTCAGA 
CCCAATGAAG GCAGTGATGG AAGCAGGCAT CCAGGAGTTC CCTCTGTTGA GAAGTCCAGA 
GGTGAGACAG CTGGCGATGA GCGGTGTGCA AAGGGGAAAG GCTTCGTGAA GCAGCCCTCC 
TGTATCAGGG TGGCTGGGCC TGATGAGAAA GGAGAGGACT CCAGGCGGGC AGCTGCAAGC 
CTTCCACCGC ACGATAGCCA CTGGAAGCCC AGCAGGCGGC ATGACACAGA ACCCAAGGCC 
AAATGTGCCC CCCAGAAAAG GCGCACTCAA GAGCTCAGAG GAGGAAGGTG CTCTCCGGCT 
GGTTCTAGCC GCCCTGGCAG TGCCCGGGGG GAGGCGGTCC ATGCTGGGCA GAATCCTCCC 
CACCATCGTA CACCAAGAAA CAAAGTGACA CAAGCCAAGC TCACAGGAGG GCTCTATTCA 
CATTTGCCAC AGAGCACAGA GGAGTTGAGG TCAGGAGCTA GGAGGCTGGA GACATCTACC 
CTGTCCGAGG ACTTTCAGGT ATCTAAGGAG ACTGATCCAG CACCTGGTCC CCTCTCTGGG 
CAGAGTGTGA ATATTGACCT TCTCCCCGTA GAGCTCCGAC TGCAGATAAT TCAGAGAGAA 
CGAAGGAGGA AGGAGCTGTT TCGCAAAAAG AACAAGGCAG CAGCAGTCAT CCAGCGCGCC 
TGGCGAAGCT ACCAGCTCAG GAAGCACCTG TCCCACCTTC GGCATATGAA GCAGCTTGGA 
GCTGGAGATG TGGACAGATG GAGGCAAGAG TCTACAGCAT TGCTCCTCCA GGTTTGGAGG 
AAGGAACTGG AACTAAAATT CCCCCAAACC ACTGCAGTAA GCAAGGCCCC CAAGAGTCCA 
TCCAAGGGCA CCTCAGGCAC AAAGTCCACC AAGCACTCAG TGCTTAAGCA AATCTATGGT 
TGTTCTCACG AAGGGAAAAT ACATCATCCT ACAAGATCTG TAAAAGCCTC TTCTGTGCTG 
CGTCTCAACT CAGTGAGCAA CCTACAGTGT ATACATCTCC TTGAGAACAG TGGAAGATCA 
AAGAACTTTT CTTATAACCT GCAATCAGCT ACTCAGCCAA AAAACAAAAC AAAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305311.1
CDS	1246..3465
Translation	MWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSCRPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSPGGSLGGALQKEQHVSSDLQGTNSRRPNETAREHSKGQSACVHFRPNEGSDGSRHPGVPSVEKSRGETAGDERCAKGKGFVKQPSCIRVAGPDEKGEDSRRAAASLPPHDSHWKPSRRHDTEPKAKCAPQKRRTQELRGGRCSPAGSSRPGSARGEAVHAGQNPPHHRTPRNKVTQAKLTGGLYSHLPQSTEELRSGARRLETSTLSEDFQVSKETDPAPGPLSGQSVNIDLLPVELRLQIIQRERRRKELFRKKNKAAAVIQRAWRSYQLRKHLSHLRHMKQLGAGDVDRWRQESTALLLQVWRKELELKFPQTTAVSKAPKSPSKGTSGTKSTKHSVLKQIYGCSHEGKIHHPTRSVKASSVLRLNSVSNLQCIHLLENSGRSKNFSYNLQSATQPKNKTKP

Target ORF information:

RefSeq Version	NM_001318382.1
Organism	Homo sapiens(human)
Definition	Homo sapiens inversin (INVS), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318382.1

ORF Insert Sequence:

ATGTGGGCAG CTGGCAAAGG CAGTGATGAT GTCCTTAGAA CTATGCTGAG CTTAAAATCG 
GACATAGATA TTAACATGGC TGACAAATAT GGAGGTACAG CTTTGCATGC TGCTGCTCTT 
TCTGGCCATG TCAGCACCGT GAAGTTATTA CTGGAAAATA ATGCTCAAGT AGATGCTACT 
GATGTTATGA AACATACTCC ACTTTTCCGA GCCTGTGAGA TGGGACACAA AGATGTGATT 
CAGACACTCA TTAAAGGTGG AGCAAGGGTA GATCTAGTTG ACCAAGATGG ACATTCTCTT 
CTACATTGGG CAGCACTGGG AGGAAATGCT GATGTTTGCC AGATATTAAT AGAAAATAAG 
ATCAATCCAA ATGTCCAGGA TTATGCAGGA AGAACCCCTT TGCAGTGTGC AGCATATGGA 
GGCTATATCA ACTGCATGGC AGTTCTCATG GAAAACAATG CAGACCCTAA CATTCAAGAC 
AAAGAGGGAA GAACAGCTTT GCATTGGTCC TGCAACAATG GATACCTTGA TGCCATTAAA 
TTACTGCTAG ACTTTGCTGC TTTCCCTAAT CAGATGGAAA ACAATGAAGA GAGATACACA 
CCCCTTGATT ATGCTTTGCT TGGTGAGCGC CATGAAGTGA TCCAGTTCAT GTTGGAGCAC 
GGTGCCCTGT CCATCGCAGC CATACAAGAC ATCGCCGCCT TCAAAATCCA AGCTGTCTAC 
AAAGGGTACA AGGTCAGAAA AGCCTTCCGA GACAGGAAAA ATCTCCTCAT GAAGCATGAA 
CAGTTGAGAA AAGATGCTGC TGCCAAAAAG CGAGAGGAAG AAAACAAACG AAAAGAGGCA 
GAACAGCAAA AAGGAAGGCG GAGCCCAGAT TCCTGCAGAC CCCAGGCCCT TCCCTGTCTG 
CCTAGCACCC AGGATGTGCC CAGCAGGCAG AGCCGGGCCC CCAGCAAGCA GCCTCCTGCT 
GGCAACGTGG CCCAAGGCCC TGAGCCAAGA GACAGCAGAG GATCTCCAGG AGGGTCTCTA 
GGCGGAGCCC TCCAGAAGGA GCAGCATGTT TCCTCAGATT TGCAGGGAAC AAACTCCAGA 
AGGCCAAATG AAACAGCCAG AGAACATTCT AAAGGCCAAT CTGCTTGTGT CCACTTCAGA 
CCCAATGAAG GCAGTGATGG AAGCAGGCAT CCAGGAGTTC CCTCTGTTGA GAAGTCCAGA 
GGTGAGACAG CTGGCGATGA GCGGTGTGCA AAGGGGAAAG GCTTCGTGAA GCAGCCCTCC 
TGTATCAGGG TGGCTGGGCC TGATGAGAAA GGAGAGGACT CCAGGCGGGC AGCTGCAAGC 
CTTCCACCGC ACGATAGCCA CTGGAAGCCC AGCAGGCGGC ATGACACAGA ACCCAAGGCC 
AAATGTGCCC CCCAGAAAAG GCGCACTCAA GAGCTCAGAG GAGGAAGGTG CTCTCCGGCT 
GGTTCTAGCC GCCCTGGCAG TGCCCGGGGG GAGGCGGTCC ATGCTGGGCA GAATCCTCCC 
CACCATCGTA CACCAAGAAA CAAAGTGACA CAAGCCAAGC TCACAGGAGG GCTCTATTCA 
CATTTGCCAC AGAGCACAGA GGAGTTGAGG TCAGGAGCTA GGAGGCTGGA GACATCTACC 
CTGTCCGAGG ACTTTCAGGT ATCTAAGGAG ACTGATCCAG CACCTGGTCC CCTCTCTGGG 
CAGAGTGTGA ATATTGACCT TCTCCCCGTA GAGCTCCGAC TGCAGATAAT TCAGAGAGAA 
CGAAGGAGGA AGGAGCTGTT TCGCAAAAAG AACAAGGCAG CAGCAGTCAT CCAGCGCGCC 
TGGCGAAGCT ACCAGCTCAG GAAGCACCTG TCCCACCTTC GGCATATGAA GCAGCTTGGA 
GCTGGAGATG TGGACAGATG GAGGCAAGAG TCTACAGCAT TGCTCCTCCA GGTTTGGAGG 
AAGGAACTGG AACTAAAATT CCCCCAAACC ACTGCAGTAA GCAAGGCCCC CAAGAGTCCA 
TCCAAGGGCA CCTCAGGCAC AAAGTCCACC AAGCACTCAG TGCTTAAGCA AATCTATGGT 
TGTTCTCACG AAGGGAAAAT ACATCATCCT ACAAGATCTG TAAAAGCCTC TTCTGTGCTG 
CGTCTCAACT CAGTGAGCAA CCTACAGTGT ATACATCTCC TTGAGAACAG TGGAAGATCA 
AAGAACTTTT CTTATAACCT GCAATCAGCT ACTCAGCCAA AAAACAAAAC AAAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INVS ( NM_001318381.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305310.1 Homo sapiens inversin (INVS), transcript variant 4, mRNA.

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CloneID	OHu101991
Clone ID Related Accession (Same CDS sequence)	NM_001318381.1
Accession Version	NM_001318381.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2910bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Homo sapiens(human)
Product	inversin isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB217652.1, BC063847.1, BC112351.1 and AL445214.7. On Jan 6, 2016 this sequence version replaced NR_051962.1. Transcript Variant: This variant (4) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (c) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC063847.1, SRR1163657.436966.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAACTCT TACTTACACG CAGAGCAAAC TGGATGCAAA AGGATCTGGA AGAGATGACT 
CCTTTGCACT TGACCACCCG GCACAGGAGC CCTAAGTGTT TGGCACTTCT GCTGAAGTTT 
ATGGCACCAG GAGAAGTGGA TACACAGGAT AAAAACAAGC AAACAGCTCT GCATTGGAGT 
GCCTACTACA ATAACCCTGA GCATGTGAAG CTGCTCATCA AGCATGATTC TAACATTGGG 
ATTCCTGATG TTGAAGGCAA GATCCCACTT CACTGGGCAG CCAACCATAA AGATCCAAGT 
GCTGTTCACA CAGTGAGATG CATTCTGGAT GCTGCTCCAA CAGAGTCTTT ACTGAACTGG 
CAAGACTACG AGGGTCGAAC TCCTCTTCAC TTTGCAGTTG CTGATGGGAA TGTGACCGTG 
GTTGATGTCT TGACCTCATA TGAAAGCTGC AATATAACGT CTTATGATAA CTTATTTCGA 
ACCCCACTGC ACTGGGCAGC TTTATTAGGC CATGCACAGA TTGTCCATCT CCTTTTAGAA 
AGAAATAAGT CTGGAACTAT CCCATCTGAC AGCCAAGGAG CCACACCTTT GCACTATGCT 
GCTCAGAGTA ACTTTGCTGA AACGGTTAAA GTGTTTTTAA AACATCCTTC AGTGAAAGAT 
GATTCAGACC TGGAAGGAAG AACATCCTTT ATGTGGGCAG CTGGCAAAGG CAGTGATGAT 
GTCCTTAGAA CTATGCTGAG CTTAAAATCG GACATAGATA TTAACATGGC TGACAAATAT 
GGAGGTACAG CTTTGCATGC TGCTGCTCTT TCTGGCCATG TCAGCACCGT GAAGTTATTA 
CTGGAAAATA ATGCTCAAGT AGATGCTACT GATGTTATGA AACATACTCC ACTTTTCCGA 
GCCTGTGAGA TGGGACACAA AGATGTGATT CAGACACTCA TTAAAGGTGG AGCAAGGGTA 
GATCTAGTTG ACCAAGATGG ACATTCTCTT CTACATTGGG CAGCACTGGG AGGAAATGCT 
GATGTTTGCC AGATATTAAT AGAAAATAAG ATCAATCCAA ATGTCCAGGA TTATGCAGGA 
AGAACCCCTT TGCAGTGTGC AGCATATGGA GGCTATATCA ACTGCATGGC AGTTCTCATG 
GAAAACAATG CAGACCCTAA CATTCAAGAC AAAGAGGGAA GAACAGCTTT GCATTGGTCC 
TGCAACAATG GATACCTTGA TGCCATTAAA TTACTGCTAG ACTTTGCTGC TTTCCCTAAT 
CAGATGGAAA ACAATGAAGA GAGATACACA CCCCTTGATT ATGCTTTGCT TGGTGAGCGC 
CATGAAGTGA TCCAGTTCAT GTTGGAGCAC GGTGCCCTGT CCATCGCAGC CATACAAGAC 
ATCGCCGCCT TCAAAATCCA AGCTGTCTAC AAAGGGTACA AGGTCAGAAA AGCCTTCCGA 
GACAGGAAAA ATCTCCTCAT GAAGCATGAA CAGTTGAGAA AAGATGCTGC TGCCAAAAAG 
CGAGAGGAAG AAAACAAACG AAAAGAGGCA GAACAGCAAA AAGGAAGGCG GAGCCCAGAT 
TCCTGCAGAC CCCAGGCCCT TCCCTGTCTG CCTAGCACCC AGGATGTGCC CAGCAGGCAG 
AGCCGGGCCC CCAGCAAGCA GCCTCCTGCT GGCAACGTGG CCCAAGGCCC TGAGCCAAGA 
GACAGCAGAG GATCTCCAGG AGGGTCTCTA GGCGGAGCCC TCCAGAAGGA GCAGCATGTT 
TCCTCAGATT TGCAGGGAAC AAACTCCAGA AGGCCAAATG AAACAGCCAG AGAACATTCT 
AAAGGCCAAT CTGCTTGTGT CCACTTCAGA CCCAATGAAG GCAGTGATGG AAGCAGGCAT 
CCAGGAGTTC CCTCTGTTGA GAAGTCCAGA GGTGAGACAG CTGGCGATGA GCGGTGTGCA 
AAGGGGAAAG GCTTCGTGAA GCAGCCCTCC TGTATCAGGG TGGCTGGGCC TGATGAGAAA 
GGAGAGGACT CCAGGCGGGC AGCTGCAAGC CTTCCACCGC ACGATAGCCA CTGGAAGCCC 
AGCAGGCGGC ATGACACAGA ACCCAAGGCC AAATGTGCCC CCCAGAAAAG GCGCACTCAA 
GAGCTCAGAG GAGGAAGGTG CTCTCCGGCT GGTTCTAGCC GCCCTGGCAG TGCCCGGGGG 
GAGGCGGTCC ATGCTGGGCA GAATCCTCCC CACCATCGTA CACCAAGAAA CAAAGTGACA 
CAAGCCAAGC TCACAGGAGG GCTCTATTCA CATTTGCCAC AGAGCACAGA GGAGTTGAGG 
TCAGGAGCTA GGAGGCTGGA GACATCTACC CTGTCCGAGG ACTTTCAGGT ATCTAAGGAG 
ACTGATCCAG CACCTGGTCC CCTCTCTGGG CAGAGTGTGA ATATTGACCT TCTCCCCGTA 
GAGCTCCGAC TGCAGATAAT TCAGAGAGAA CGAAGGAGGA AGGAGCTGTT TCGCAAAAAG 
AACAAGGCAG CAGCAGTCAT CCAGCGCGCC TGGCGAAGCT ACCAGCTCAG GAAGCACCTG 
TCCCACCTTC GGCATATGAA GCAGCTTGGA GCTGGAGATG TGGACAGATG GAGGCAAGAG 
TCTACAGCAT TGCTCCTCCA GGTTTGGAGG AAGGAACTGG AACTAAAATT CCCCCAAACC 
ACTGCAGTAA GCAAGGCCCC CAAGAGTCCA TCCAAGGGCA CCTCAGGCAC AAAGTCCACC 
AAGCACTCAG TGCTTAAGCA AATCTATGGT TGTTCTCACG AAGGGAAAAT ACATCATCCT 
ACAAGATCTG TAAAAGCCTC TTCTGTGCTG CGTCTCAACT CAGTGAGCAA CCTACAGTGT 
ATACATCTCC TTGAGAACAG TGGAAGATCA AAGAACTTTT CTTATAACCT GCAATCAGCT 
ACTCAGCCAA AAAACAAAAC AAAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305310.1
CDS	633..3542
Translation	MKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSCRPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSPGGSLGGALQKEQHVSSDLQGTNSRRPNETAREHSKGQSACVHFRPNEGSDGSRHPGVPSVEKSRGETAGDERCAKGKGFVKQPSCIRVAGPDEKGEDSRRAAASLPPHDSHWKPSRRHDTEPKAKCAPQKRRTQELRGGRCSPAGSSRPGSARGEAVHAGQNPPHHRTPRNKVTQAKLTGGLYSHLPQSTEELRSGARRLETSTLSEDFQVSKETDPAPGPLSGQSVNIDLLPVELRLQIIQRERRRKELFRKKNKAAAVIQRAWRSYQLRKHLSHLRHMKQLGAGDVDRWRQESTALLLQVWRKELELKFPQTTAVSKAPKSPSKGTSGTKSTKHSVLKQIYGCSHEGKIHHPTRSVKASSVLRLNSVSNLQCIHLLENSGRSKNFSYNLQSATQPKNKTKP

Target ORF information:

RefSeq Version	NM_001318381.1
Organism	Homo sapiens(human)
Definition	Homo sapiens inversin (INVS), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318381.1

ORF Insert Sequence:

ATGAAACTCT TACTTACACG CAGAGCAAAC TGGATGCAAA AGGATCTGGA AGAGATGACT 
CCTTTGCACT TGACCACCCG GCACAGGAGC CCTAAGTGTT TGGCACTTCT GCTGAAGTTT 
ATGGCACCAG GAGAAGTGGA TACACAGGAT AAAAACAAGC AAACAGCTCT GCATTGGAGT 
GCCTACTACA ATAACCCTGA GCATGTGAAG CTGCTCATCA AGCATGATTC TAACATTGGG 
ATTCCTGATG TTGAAGGCAA GATCCCACTT CACTGGGCAG CCAACCATAA AGATCCAAGT 
GCTGTTCACA CAGTGAGATG CATTCTGGAT GCTGCTCCAA CAGAGTCTTT ACTGAACTGG 
CAAGACTACG AGGGTCGAAC TCCTCTTCAC TTTGCAGTTG CTGATGGGAA TGTGACCGTG 
GTTGATGTCT TGACCTCATA TGAAAGCTGC AATATAACGT CTTATGATAA CTTATTTCGA 
ACCCCACTGC ACTGGGCAGC TTTATTAGGC CATGCACAGA TTGTCCATCT CCTTTTAGAA 
AGAAATAAGT CTGGAACTAT CCCATCTGAC AGCCAAGGAG CCACACCTTT GCACTATGCT 
GCTCAGAGTA ACTTTGCTGA AACGGTTAAA GTGTTTTTAA AACATCCTTC AGTGAAAGAT 
GATTCAGACC TGGAAGGAAG AACATCCTTT ATGTGGGCAG CTGGCAAAGG CAGTGATGAT 
GTCCTTAGAA CTATGCTGAG CTTAAAATCG GACATAGATA TTAACATGGC TGACAAATAT 
GGAGGTACAG CTTTGCATGC TGCTGCTCTT TCTGGCCATG TCAGCACCGT GAAGTTATTA 
CTGGAAAATA ATGCTCAAGT AGATGCTACT GATGTTATGA AACATACTCC ACTTTTCCGA 
GCCTGTGAGA TGGGACACAA AGATGTGATT CAGACACTCA TTAAAGGTGG AGCAAGGGTA 
GATCTAGTTG ACCAAGATGG ACATTCTCTT CTACATTGGG CAGCACTGGG AGGAAATGCT 
GATGTTTGCC AGATATTAAT AGAAAATAAG ATCAATCCAA ATGTCCAGGA TTATGCAGGA 
AGAACCCCTT TGCAGTGTGC AGCATATGGA GGCTATATCA ACTGCATGGC AGTTCTCATG 
GAAAACAATG CAGACCCTAA CATTCAAGAC AAAGAGGGAA GAACAGCTTT GCATTGGTCC 
TGCAACAATG GATACCTTGA TGCCATTAAA TTACTGCTAG ACTTTGCTGC TTTCCCTAAT 
CAGATGGAAA ACAATGAAGA GAGATACACA CCCCTTGATT ATGCTTTGCT TGGTGAGCGC 
CATGAAGTGA TCCAGTTCAT GTTGGAGCAC GGTGCCCTGT CCATCGCAGC CATACAAGAC 
ATCGCCGCCT TCAAAATCCA AGCTGTCTAC AAAGGGTACA AGGTCAGAAA AGCCTTCCGA 
GACAGGAAAA ATCTCCTCAT GAAGCATGAA CAGTTGAGAA AAGATGCTGC TGCCAAAAAG 
CGAGAGGAAG AAAACAAACG AAAAGAGGCA GAACAGCAAA AAGGAAGGCG GAGCCCAGAT 
TCCTGCAGAC CCCAGGCCCT TCCCTGTCTG CCTAGCACCC AGGATGTGCC CAGCAGGCAG 
AGCCGGGCCC CCAGCAAGCA GCCTCCTGCT GGCAACGTGG CCCAAGGCCC TGAGCCAAGA 
GACAGCAGAG GATCTCCAGG AGGGTCTCTA GGCGGAGCCC TCCAGAAGGA GCAGCATGTT 
TCCTCAGATT TGCAGGGAAC AAACTCCAGA AGGCCAAATG AAACAGCCAG AGAACATTCT 
AAAGGCCAAT CTGCTTGTGT CCACTTCAGA CCCAATGAAG GCAGTGATGG AAGCAGGCAT 
CCAGGAGTTC CCTCTGTTGA GAAGTCCAGA GGTGAGACAG CTGGCGATGA GCGGTGTGCA 
AAGGGGAAAG GCTTCGTGAA GCAGCCCTCC TGTATCAGGG TGGCTGGGCC TGATGAGAAA 
GGAGAGGACT CCAGGCGGGC AGCTGCAAGC CTTCCACCGC ACGATAGCCA CTGGAAGCCC 
AGCAGGCGGC ATGACACAGA ACCCAAGGCC AAATGTGCCC CCCAGAAAAG GCGCACTCAA 
GAGCTCAGAG GAGGAAGGTG CTCTCCGGCT GGTTCTAGCC GCCCTGGCAG TGCCCGGGGG 
GAGGCGGTCC ATGCTGGGCA GAATCCTCCC CACCATCGTA CACCAAGAAA CAAAGTGACA 
CAAGCCAAGC TCACAGGAGG GCTCTATTCA CATTTGCCAC AGAGCACAGA GGAGTTGAGG 
TCAGGAGCTA GGAGGCTGGA GACATCTACC CTGTCCGAGG ACTTTCAGGT ATCTAAGGAG 
ACTGATCCAG CACCTGGTCC CCTCTCTGGG CAGAGTGTGA ATATTGACCT TCTCCCCGTA 
GAGCTCCGAC TGCAGATAAT TCAGAGAGAA CGAAGGAGGA AGGAGCTGTT TCGCAAAAAG 
AACAAGGCAG CAGCAGTCAT CCAGCGCGCC TGGCGAAGCT ACCAGCTCAG GAAGCACCTG 
TCCCACCTTC GGCATATGAA GCAGCTTGGA GCTGGAGATG TGGACAGATG GAGGCAAGAG 
TCTACAGCAT TGCTCCTCCA GGTTTGGAGG AAGGAACTGG AACTAAAATT CCCCCAAACC 
ACTGCAGTAA GCAAGGCCCC CAAGAGTCCA TCCAAGGGCA CCTCAGGCAC AAAGTCCACC 
AAGCACTCAG TGCTTAAGCA AATCTATGGT TGTTCTCACG AAGGGAAAAT ACATCATCCT 
ACAAGATCTG TAAAAGCCTC TTCTGTGCTG CGTCTCAACT CAGTGAGCAA CCTACAGTGT 
ATACATCTCC TTGAGAACAG TGGAAGATCA AAGAACTTTT CTTATAACCT GCAATCAGCT 
ACTCAGCCAA AAAACAAAAC AAAACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Inversin correlates with the malignant phenotype of non-small cell lung cancer and promotes the invasiveness of lung cancer cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(6)1010428317691177(2017 Jun)
Jiang GY,Zhang Y,Zhang XP,Lin XY,Yu JH,Wang EH

Phosphorylation-dependent Akt-Inversin interaction at the basal body of primary cilia.
The EMBO journal35(12)1346-63(2016 06)
Suizu F,Hirata N,Kimura K,Edamura T,Tanaka T,Ishigaki S,Donia T,Noguchi H,Iwanaga T,Noguchi M

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Nature genetics45(8)951-6(2013 Aug)
Hoff S,Halbritter J,Epting D,Frank V,Nguyen TM,van Reeuwijk J,Boehlke C,Schell C,Yasunaga T,Helmst?dter M,Mergen M,Filhol E,Boldt K,Horn N,Ueffing M,Otto EA,Eisenberger T,Elting MW,van Wijk JA,Bockenhauer D,Sebire NJ,Rittig S,Vyberg M,Ring T,Pohl M,Pape L,Neuhaus TJ,Elshakhs NA,Koon SJ,Harris PC,Grahammer F,Huber TB,Kuehn EW,Kramer-Zucker A,Bolz HJ,Roepman R,Saunier S,Walz G,Hildebrandt F,Bergmann C,Lienkamp SS

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INVS cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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