MTBP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MTBP
Entrez Gene ID	27085
Full Name	MDM2 binding protein
Synonyms	MDM2BP
General protein information	Preferred Names MDM2 binding protein Names mdm2-binding protein MDM2 (mouse double minute 2)-binding protein, 104kD Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q24.12
Summary	This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012].
Disorder MIM:	605927

mRNA and Protein(s)

mRNA	Protein	Name
NM_022045.4	NP_071328.2	mdm2-binding protein
NM_022045.5	NP_071328.2	mdm2-binding protein
XM_011516962.2	XP_011515264.1	mdm2-binding protein isoform X1
XM_011516963.2	XP_011515265.1	mdm2-binding protein isoform X2

Pathways from BioSystems

Homologies

	MTBP	XP_001098134.1
Bos taurus (cattle)	MTBP	NP_001180106.1
Gallus gallus (chicken)	MTBP	XP_418460.4
Xenopus tropicalis (tropical clawed frog)	mtbp	NP_001107690.1
Homo sapiens (human)	MTBP	NP_071328.2
Pan troglodytes (chimpanzee)	MTBP	XP_519930.2
Canis lupus familiaris (dog)	MTBP	XP_851376.1
Danio rerio (zebrafish)	LOC100534898	XP_003200205.1
Rattus norvegicus (Norway rat)	Mtbp	NP_001124189.1
Mus musculus (house mouse)	Mtbp	NP_598853.3

Gene Ontology
Bibliography

Related articles in PubMed

MTBP Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Enhancing the MDM2-Mediated Degradation of E-Cadherin.
Lu S, Zhou W, Wei H, He L, Li L
Digestive diseases and sciences60(12)3681-90(2015 Dec)

MTBP inhibits migration and metastasis of hepatocellular carcinoma.
Bi Q, Ranjan A, Fan R, Agarwal N, Welch DR, Weinman SA, Ding J, Iwakuma T
Clinical & experimental metastasis32(4)301-11(2015 Apr)

Epidemiological and genome-wide association study of gastritis or gastric ulcer in korean populations.
Oh S, Oh S
Genomics & informatics12(3)127-33(2014 Sep)

MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival.
Grieb BC, Chen X, Eischen CM
Molecular cancer research : MCR12(9)1216-24(2014 Sep)

Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.
Grieb BC, Gramling MW, Arrate MP, Chen X, Beauparlant SL, Haines DS, Xiao H, Eischen CM
Cancer research74(13)3591-602(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data show that MTBP aggravates the invasion and metastasis of HCC by promoting the MDM2-mediated degradation of E-cadherin.
Title: MTBP Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Enhancing the MDM2-Mediated Degradation of E-Cadherin.

Overexpression of MTBP resulted in the suppression of the migratory and metastatic potential of Hepatocellular carcinoma cells, while its downregulation increased the migration.
Title: MTBP inhibits migration and metastasis of hepatocellular carcinoma.

MTBP significantly contributes to breast cancer survival and is a potential novel therapeutic target in Triple-negative breast cancer .
Title: MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival.

MTBP associated with MYC at promoters and increased MYC-mediated transcription, proliferation, neoplastic transformation, and tumor development.
Title: Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.

MTBP acts with Treslin/TICRR to integrate signals from cell cycle and DNA damage response pathways to control the initiation of DNA replication in human cells.
Title: Identification of a heteromeric complex that promotes DNA replication origin firing in human cells.

The following MTBP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MTBP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22109	NM_022045.5 Latest version!	Homo sapiens MDM2 binding protein (MTBP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu67047	XM_011516962.2 Latest version!	Homo sapiens MDM2 binding protein (MTBP), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu67048	XM_011516963.2 Latest version!	Homo sapiens MDM2 binding protein (MTBP), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu22109	NM_022045.4	Homo sapiens MDM2 binding protein (MTBP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MTBP ( NM_022045.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071328.2 Homo sapiens MDM2 binding protein (MTBP), mRNA.

Price & Availability↑

CloneID	OHu22109
Clone ID Related Accession (Same CDS sequence)	NM_022045.4 , NM_022045.5
Accession Version	NM_022045.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2715bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	mdm2-binding protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107877.4 and BC013136.1. This sequence is a reference standard in the RefSeqGene project. On Aug 9, 2012 this sequence version replaced NM_022045.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013136.1, SRR1803614.282.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAAA GACGAAAGTT GGCAAAGCAG CCTGAAACAG TTTCTGTTGC TGAACTCAAA 
AGTCTGTTAG TACTCACAAG GAAACACTTT TTAGATTATT TTGATGCTGT GATTCCTAAA 
ATGATTCTAA GAAAGATGGA CAAAATTAAA ACCTTCAATA TATTAAATGA TTTTAGTCCA 
GTGGAACCTA ATTCCTCAAG TCTAATGGAA ACCAATCCTC TGGAATGGCC AGAAAGGCAT 
GTTCTTCAAA ATTTGGAAAC TTTTGAAAAA ACTAAACAAA AAATGAGAAC TGGTTCATTA 
CCTCATTCAT CTGAACAGTT GCTGGGCCAC AAAGAGGGTC CTCGGGACTC AATCACATTG 
TTGGATGCTA AAGAATTGCT GAAGTACTTT ACCTCAGATG GATTACCCAT TGGAGATCTT 
CAACCTTTAC CGATTCAAAA GGGGGAAAAG ACTTTTGTTT TGACACCAGA ACTTAGTCCT 
GGGAAACTTC AGGTCTTACC TTTTGAGAAA GCCTCAGTAT GTCATTATCA TGGAATTGAA 
TATTGCTTGG ATGACCGAAA AGCTTTGGAA AGAGATGGAG GATTTTCTGA ACTTCAGTCT 
CGTCTTATTC GTTATGAAAC TCAAACTACC TGCACCAGAG AAAGTTTTCC AGTACCTACT 
GTGTTGAGCC CTCTTCCATC TCCTGTAGTT TCGTCAGATC CTGGAAGTGT CCCTGACGGA 
GAAGTTTTAC AAAATGAACT TCGAACTGAA GTATCCCGAT TGAAACGGAG ATCTAAAGAT 
CTGAATTGCC TTTATCCCAG AAAAAGACTT GTGAAATCTG AAAGTTCAGA GTCTCTTCTT 
TCTCAGACAA CTGGTAATAG TAATCACTAT CATCATCATG TGACATCCAG AAAGCCACAA 
ACAGAACGGT CCTTACCAGT GACTTGTCCA TTGGTTCCAA TTCCTAGCTG TGAAACTCCA 
AAACTTGCTA CAAAGACCAG TTCAGGTCAA AAAAGTATGC ATGAATCAAA AACATCAAGG 
CAAATTAAGG AATCAAGATC ACAGAAACAC ACACGGATAC TGAAAGAAGT AGTTACTGAA 
ACCCTGAAGA AACACAGTAT TACCGAGACT CATGAATGTT TCACTGCATG CAGCCAGCGT 
CTCTTTGAAA TCTCTAAGTT CTATCTAAAG GATCTTAAAA CTTCAAGGGG TCTATTTGAA 
GAAATGAAGA AAACAGCAAA CAACAATGCT GTACAGGTGA TTGACTGGGT ATTAGAAAAG 
ACAAGCAAGA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071328.2
CDS	74..2788
Translation	MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINPEDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEECLGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKLKDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWRGKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTISNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHSANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEECLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITLLDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEKTSKK

Target ORF information:

RefSeq Version	NM_022045.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MDM2 binding protein (MTBP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022045.4

ORF Insert Sequence:

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAAA GACGAAAGTT GGCAAAGCAG CCTGAAACAG TTTCTGTTGC TGAACTCAAA 
AGTCTGTTAG TACTCACAAG GAAACACTTT TTAGATTATT TTGATGCTGT GATTCCTAAA 
ATGATTCTAA GAAAGATGGA CAAAATTAAA ACCTTCAATA TATTAAATGA TTTTAGTCCA 
GTGGAACCTA ATTCCTCAAG TCTAATGGAA ACCAATCCTC TGGAATGGCC AGAAAGGCAT 
GTTCTTCAAA ATTTGGAAAC TTTTGAAAAA ACTAAACAAA AAATGAGAAC TGGTTCATTA 
CCTCATTCAT CTGAACAGTT GCTGGGCCAC AAAGAGGGTC CTCGGGACTC AATCACATTG 
TTGGATGCTA AAGAATTGCT GAAGTACTTT ACCTCAGATG GATTACCCAT TGGAGATCTT 
CAACCTTTAC CGATTCAAAA GGGGGAAAAG ACTTTTGTTT TGACACCAGA ACTTAGTCCT 
GGGAAACTTC AGGTCTTACC TTTTGAGAAA GCCTCAGTAT GTCATTATCA TGGAATTGAA 
TATTGCTTGG ATGACCGAAA AGCTTTGGAA AGAGATGGAG GATTTTCTGA ACTTCAGTCT 
CGTCTTATTC GTTATGAAAC TCAAACTACC TGCACCAGAG AAAGTTTTCC AGTACCTACT 
GTGTTGAGCC CTCTTCCATC TCCTGTAGTT TCGTCAGATC CTGGAAGTGT CCCTGACGGA 
GAAGTTTTAC AAAATGAACT TCGAACTGAA GTATCCCGAT TGAAACGGAG ATCTAAAGAT 
CTGAATTGCC TTTATCCCAG AAAAAGACTT GTGAAATCTG AAAGTTCAGA GTCTCTTCTT 
TCTCAGACAA CTGGTAATAG TAATCACTAT CATCATCATG TGACATCCAG AAAGCCACAA 
ACAGAACGGT CCTTACCAGT GACTTGTCCA TTGGTTCCAA TTCCTAGCTG TGAAACTCCA 
AAACTTGCTA CAAAGACCAG TTCAGGTCAA AAAAGTATGC ATGAATCAAA AACATCAAGG 
CAAATTAAGG AATCAAGATC ACAGAAACAC ACACGGATAC TGAAAGAAGT AGTTACTGAA 
ACCCTGAAGA AACACAGTAT TACCGAGACT CATGAATGTT TCACTGCATG CAGCCAGCGT 
CTCTTTGAAA TCTCTAAGTT CTATCTAAAG GATCTTAAAA CTTCAAGGGG TCTATTTGAA 
GAAATGAAGA AAACAGCAAA CAACAATGCT GTACAGGTGA TTGACTGGGT ATTAGAAAAG 
ACAAGCAAGA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MTBP ( NM_022045.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_071328.2 Homo sapiens MDM2 binding protein (MTBP), mRNA.

Price & Availability↑

CloneID	OHu22109
Clone ID Related Accession (Same CDS sequence)	NM_022045.4 , NM_022045.5
Accession Version	NM_022045.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2715bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	mdm2-binding protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107877.4, BC013136.1 and AC105142.4. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_022045.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.282.1, BC013136.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000305949.6/ ENSP00000303398.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAAA GACGAAAGTT GGCAAAGCAG CCTGAAACAG TTTCTGTTGC TGAACTCAAA 
AGTCTGTTAG TACTCACAAG GAAACACTTT TTAGATTATT TTGATGCTGT GATTCCTAAA 
ATGATTCTAA GAAAGATGGA CAAAATTAAA ACCTTCAATA TATTAAATGA TTTTAGTCCA 
GTGGAACCTA ATTCCTCAAG TCTAATGGAA ACCAATCCTC TGGAATGGCC AGAAAGGCAT 
GTTCTTCAAA ATTTGGAAAC TTTTGAAAAA ACTAAACAAA AAATGAGAAC TGGTTCATTA 
CCTCATTCAT CTGAACAGTT GCTGGGCCAC AAAGAGGGTC CTCGGGACTC AATCACATTG 
TTGGATGCTA AAGAATTGCT GAAGTACTTT ACCTCAGATG GATTACCCAT TGGAGATCTT 
CAACCTTTAC CGATTCAAAA GGGGGAAAAG ACTTTTGTTT TGACACCAGA ACTTAGTCCT 
GGGAAACTTC AGGTCTTACC TTTTGAGAAA GCCTCAGTAT GTCATTATCA TGGAATTGAA 
TATTGCTTGG ATGACCGAAA AGCTTTGGAA AGAGATGGAG GATTTTCTGA ACTTCAGTCT 
CGTCTTATTC GTTATGAAAC TCAAACTACC TGCACCAGAG AAAGTTTTCC AGTACCTACT 
GTGTTGAGCC CTCTTCCATC TCCTGTAGTT TCGTCAGATC CTGGAAGTGT CCCTGACGGA 
GAAGTTTTAC AAAATGAACT TCGAACTGAA GTATCCCGAT TGAAACGGAG ATCTAAAGAT 
CTGAATTGCC TTTATCCCAG AAAAAGACTT GTGAAATCTG AAAGTTCAGA GTCTCTTCTT 
TCTCAGACAA CTGGTAATAG TAATCACTAT CATCATCATG TGACATCCAG AAAGCCACAA 
ACAGAACGGT CCTTACCAGT GACTTGTCCA TTGGTTCCAA TTCCTAGCTG TGAAACTCCA 
AAACTTGCTA CAAAGACCAG TTCAGGTCAA AAAAGTATGC ATGAATCAAA AACATCAAGG 
CAAATTAAGG AATCAAGATC ACAGAAACAC ACACGGATAC TGAAAGAAGT AGTTACTGAA 
ACCCTGAAGA AACACAGTAT TACCGAGACT CATGAATGTT TCACTGCATG CAGCCAGCGT 
CTCTTTGAAA TCTCTAAGTT CTATCTAAAG GATCTTAAAA CTTCAAGGGG TCTATTTGAA 
GAAATGAAGA AAACAGCAAA CAACAATGCT GTACAGGTGA TTGACTGGGT ATTAGAAAAG 
ACAAGCAAGA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071328.2
CDS	53..2767
Translation	MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINPEDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEECLGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKLKDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWRGKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTISNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHSANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEECLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITLLDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEKTSKK

Target ORF information:

RefSeq Version	NM_022045.5
Organism	Homo sapiens(human)
Definition	Homo sapiens MDM2 binding protein (MTBP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022045.5

ORF Insert Sequence:

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAAA GACGAAAGTT GGCAAAGCAG CCTGAAACAG TTTCTGTTGC TGAACTCAAA 
AGTCTGTTAG TACTCACAAG GAAACACTTT TTAGATTATT TTGATGCTGT GATTCCTAAA 
ATGATTCTAA GAAAGATGGA CAAAATTAAA ACCTTCAATA TATTAAATGA TTTTAGTCCA 
GTGGAACCTA ATTCCTCAAG TCTAATGGAA ACCAATCCTC TGGAATGGCC AGAAAGGCAT 
GTTCTTCAAA ATTTGGAAAC TTTTGAAAAA ACTAAACAAA AAATGAGAAC TGGTTCATTA 
CCTCATTCAT CTGAACAGTT GCTGGGCCAC AAAGAGGGTC CTCGGGACTC AATCACATTG 
TTGGATGCTA AAGAATTGCT GAAGTACTTT ACCTCAGATG GATTACCCAT TGGAGATCTT 
CAACCTTTAC CGATTCAAAA GGGGGAAAAG ACTTTTGTTT TGACACCAGA ACTTAGTCCT 
GGGAAACTTC AGGTCTTACC TTTTGAGAAA GCCTCAGTAT GTCATTATCA TGGAATTGAA 
TATTGCTTGG ATGACCGAAA AGCTTTGGAA AGAGATGGAG GATTTTCTGA ACTTCAGTCT 
CGTCTTATTC GTTATGAAAC TCAAACTACC TGCACCAGAG AAAGTTTTCC AGTACCTACT 
GTGTTGAGCC CTCTTCCATC TCCTGTAGTT TCGTCAGATC CTGGAAGTGT CCCTGACGGA 
GAAGTTTTAC AAAATGAACT TCGAACTGAA GTATCCCGAT TGAAACGGAG ATCTAAAGAT 
CTGAATTGCC TTTATCCCAG AAAAAGACTT GTGAAATCTG AAAGTTCAGA GTCTCTTCTT 
TCTCAGACAA CTGGTAATAG TAATCACTAT CATCATCATG TGACATCCAG AAAGCCACAA 
ACAGAACGGT CCTTACCAGT GACTTGTCCA TTGGTTCCAA TTCCTAGCTG TGAAACTCCA 
AAACTTGCTA CAAAGACCAG TTCAGGTCAA AAAAGTATGC ATGAATCAAA AACATCAAGG 
CAAATTAAGG AATCAAGATC ACAGAAACAC ACACGGATAC TGAAAGAAGT AGTTACTGAA 
ACCCTGAAGA AACACAGTAT TACCGAGACT CATGAATGTT TCACTGCATG CAGCCAGCGT 
CTCTTTGAAA TCTCTAAGTT CTATCTAAAG GATCTTAAAA CTTCAAGGGG TCTATTTGAA 
GAAATGAAGA AAACAGCAAA CAACAATGCT GTACAGGTGA TTGACTGGGT ATTAGAAAAG 
ACAAGCAAGA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MTBP ( XM_011516962.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515264.1 Homo sapiens MDM2 binding protein (MTBP), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu67047
Clone ID Related Accession (Same CDS sequence)	XM_011516962.2
Accession Version	XM_011516962.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mdm2-binding protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516962.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAAA GACGAAAGTT GGCAAAGCAG CCTGAAACAG TTTCTGTTGC TGAACTCAAA 
AGTCTGTTAG TACTCACAAG GAAACACTTT TTAGATTATT TTGATGCTGT GATTCCTAAA 
ATGATTCTAA GAAAGATGGA CAAAATTAAA ACCTTCAATA TATTAAATGA TTTTAGTCCA 
GTGGAACCTA ATTCCTCAAG TCTAATGGAA ACCAATCCTC TGGAATGGCC AGAAAGGCAT 
GTTCTTCAAA ATTTGGAAAC TTTTGAAAAA ACTAAACAAA AAATGAGAAC TGGTTCATTA 
CCTCATTCAT CTGAACAGTT GCTGGGCCAC AAAGAGGGTC CTCGGGACTC AATCACATTG 
TTGGATGCTA AAGAATTGCT GAAGTACTTT ACCTCAGATG GATTACCCAT TGGAGATCTT 
CAACCTTTAC CGATTCAAAA GGGGGAAAAG ACTTTTGTTT TGACACCAGA ACTTAGTCCT 
GGGAAACTTC AGGTCTTACC TTTTGAGAAA GCCTCAGTAT GTCATTATCA TGGAATTGAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515264.1
CDS	71..2053
Translation	MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINPEDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEECLGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKLKDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWRGKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTISNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHSANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEECLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITLLDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIE

Target ORF information:

RefSeq Version	XM_011516962.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MDM2 binding protein (MTBP), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516962.2

ORF Insert Sequence:

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAAA GACGAAAGTT GGCAAAGCAG CCTGAAACAG TTTCTGTTGC TGAACTCAAA 
AGTCTGTTAG TACTCACAAG GAAACACTTT TTAGATTATT TTGATGCTGT GATTCCTAAA 
ATGATTCTAA GAAAGATGGA CAAAATTAAA ACCTTCAATA TATTAAATGA TTTTAGTCCA 
GTGGAACCTA ATTCCTCAAG TCTAATGGAA ACCAATCCTC TGGAATGGCC AGAAAGGCAT 
GTTCTTCAAA ATTTGGAAAC TTTTGAAAAA ACTAAACAAA AAATGAGAAC TGGTTCATTA 
CCTCATTCAT CTGAACAGTT GCTGGGCCAC AAAGAGGGTC CTCGGGACTC AATCACATTG 
TTGGATGCTA AAGAATTGCT GAAGTACTTT ACCTCAGATG GATTACCCAT TGGAGATCTT 
CAACCTTTAC CGATTCAAAA GGGGGAAAAG ACTTTTGTTT TGACACCAGA ACTTAGTCCT 
GGGAAACTTC AGGTCTTACC TTTTGAGAAA GCCTCAGTAT GTCATTATCA TGGAATTGAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MTBP ( XM_011516963.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515265.1 Homo sapiens MDM2 binding protein (MTBP), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu67048
Clone ID Related Accession (Same CDS sequence)	XM_011516963.2
Accession Version	XM_011516963.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1455bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mdm2-binding protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516963.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAGA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515265.1
CDS	71..1525
Translation	MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINPEDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEECLGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKLKDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWRGKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTISNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHSANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEECLKS

Target ORF information:

RefSeq Version	XM_011516963.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MDM2 binding protein (MTBP), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516963.2

ORF Insert Sequence:

ATGGATCGGT ACCTGCTGCT GGTGATCTGG GGGGAAGGAA AATTCCCGTC GGCGGCCAGT 
AGGGAGGCAG AACATGGGCC AGAGGTGTCG TCGGGTGAGG GTACTGAGAA TCAGCCGGAC 
TTCACAGCAG CAAATGTTTA TCACCTCTTG AAAAGAAGCA TTAGTGCTTC AATTAATCCA 
GAAGATAGTA CTTTCCCTGC CTGTTCAGTG GGAGGTATAC CTGGTTCCAA GAAGTGGTTC 
TTTGCAGTGC AGGCAATATA TGGATTTTAT CAGTTTTGTA GTTCTGATTG GCAAGAGATA 
CATTTTGATA CAGAAAAAGA TAAAATTGAA GATGTTCTTC AAACGAATAT CGAAGAATGT 
TTGGGTGCTG TTGAGTGTTT TGAAGAAGAA GACAGTAATA GCAGGGAATC ATTATCCTTG 
GCTGATCTCT ATGAAGAAGC TGCAGAAAAT TTGCATCAGC TGTCAGACAA GCTTCCTGCT 
CCTGGTAGAG CAATGGTAGA TATAATACTG TTGCTTTCTG ACAAAGATCC TCCTAAATTG 
AAAGACTATT TACCTACTGT AGGAGCATTA AAACATTTGA GAGAATGGTA TTCAGCAAAG 
ATCACTATAG CAGGAAATCA TTGTGAAATA AACTGTCAGA AAATTGCAGA ATACCTTTCT 
GCTAATGTTG TATCTTTAGA AGATCTCAGA AATGTTATTG ACTCAAAGGA ATTATGGAGG 
GGGAAAATAC AGATATGGGA AAGAAAGTTT GGATTTGAAA TTAGTTTTCC TGAATTTTGT 
TTAAAGGGAG TCACACTTAA GAATTTTAGT ACTTCTAATT TAAATACTGA CTTCCTTGCC 
AAAAAGATCA TACCATCAAA GGATAAGAAT ATTTTGCCAA AGGTTTTCCA TTATTATGGC 
CCTGCTTTAG AATTTGTGCA GATGATAAAA TTATCAGATC TACCCTCCTG CTATATGTCG 
GATATTGAAT TTGAGTTAGG ATTGACAAAC AGTACCAAAC AGAATTCTGT GTTGCTGTTG 
GAGCAGATTT CTTCTCTGTG TAGCAAGGTT GGTGCTCTTT TTGTATTGCC ATGTACCATT 
AGTAACATAC TGATTCCACC TCCCAACCAA CTCAGTTCAA GAAAATGGAA GGAATATATA 
GCTAAAAAGC CTAAAACAAT CAGTGTTCCA GATGTTGAAG TGAAAGGAGA GTGTTCTAGC 
TATTATCTCT TGTTACAAGG TAATGGCAAT AGAAGATGTA AAGCCACATT GATTCACTCA 
GCCAACCAGA TCAATGGCTC ATTTGCACTC AATTTAATTC ATGGAAAGAT GAAAACAAAG 
ACAGAAGAAG CCAAATTGAG TTTTCCTTTT GACTTATTAT CACTTCCACA TTTTTCTGGG 
GAGCAGATTG TACAGAGAGA GAAACAGTTA GCTAATGTTC AAGTTTTAGC TTTGGAAGAA 
TGCCTAAAGA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MTBP Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Enhancing the MDM2-Mediated Degradation of E-Cadherin.
Digestive diseases and sciences60(12)3681-90(2015 Dec)
Lu S,Zhou W,Wei H,He L,Li L

MTBP inhibits migration and metastasis of hepatocellular carcinoma.
Clinical & experimental metastasis32(4)301-11(2015 Apr)
Bi Q,Ranjan A,Fan R,Agarwal N,Welch DR,Weinman SA,Ding J,Iwakuma T

Epidemiological and genome-wide association study of gastritis or gastric ulcer in korean populations.
Genomics & informatics12(3)127-33(2014 Sep)
Oh S,Oh S

MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival.
Molecular cancer research : MCR12(9)1216-24(2014 Sep)
Grieb BC,Chen X,Eischen CM

Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.
Cancer research74(13)3591-602(2014 Jul)
Grieb BC,Gramling MW,Arrate MP,Chen X,Beauparlant SL,Haines DS,Xiao H,Eischen CM

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MTBP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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