GGT1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GGT1
Entrez Gene ID	2678
Full Name	gamma-glutamyltransferase 1
Synonyms	CD224,D22S672,D22S732,GGT,GGT 1,GTG
General protein information	Preferred Names gamma-glutamyltransferase 1 Names glutathione hydrolase 1 proenzyme gamma-glutamyltranspeptidase 1 glutathione hydrolase 1 leukotriene-C4 hydrolase testicular tissue protein Li 73
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q11.23
Summary	The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014].
Disorder MIM:	612346
Disorder Html:	Glutathioninuria, 231950 (1)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001288833.1	NP_001275762.1	glutathione hydrolase 1 proenzyme precursor
NM_001288833.2	NP_001275762.1	glutathione hydrolase 1 proenzyme precursor
NM_013421.2	NP_038265.2	glutathione hydrolase 1 proenzyme precursor
NM_013430.2	NP_038347.2	glutathione hydrolase 1 proenzyme precursor
NM_013421.3	NP_038265.2	glutathione hydrolase 1 proenzyme precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	GGT1	NP_001275762.1
Canis lupus familiaris (dog)	GGT1	XP_005636611.1
Gallus gallus (chicken)	GGT1	XP_004934399.1
Danio rerio (zebrafish)	ggt1b	XP_697468.3
Danio rerio (zebrafish)	ggt1a	NP_956709.1
Eremothecium gossypii	AGOS_AAR144W	NP_982686.1
Arabidopsis thaliana (thale cress)	GGT2	NP_195675.2
Mus musculus (house mouse)	Ggt1	NP_032142.1
Rattus norvegicus (Norway rat)	Ggt1	NP_446292.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000853	XP_316824.5
Caenorhabditis elegans (roundworm)	C53D5.5	NP_490714.1
Caenorhabditis elegans (roundworm)	T03D8.6	NP_001129905.1
Caenorhabditis elegans (roundworm)	H14N18.4	NP_741582.2
Saccharomyces cerevisiae (baker's yeast)	ECM38	NP_013402.1
Kluyveromyces lactis	KLLA0C05236g	XP_452434.1
Xenopus tropicalis (tropical clawed frog)	ggt1	NP_001006724.2
	GGT2	XP_001090518.1
Drosophila melanogaster (fruit fly)	CG4829	NP_001097005.1
Schizosaccharomyces pombe (fission yeast)	ggt1	NP_593457.1
Pan troglodytes (chimpanzee)	GGT1	XP_001171062.1
Bos taurus (cattle)	GGT1	NP_001193143.1
Magnaporthe oryzae (rice blast fungus)	MGG_03882	XP_003719997.1
Neurospora crassa	NCU01753	XP_957176.2
Arabidopsis thaliana (thale cress)	GGT4	NP_194650.1
Caenorhabditis elegans (roundworm)	Y7A9A.1	NP_502918.1
Schizosaccharomyces pombe (fission yeast)	ggt2	NP_593273.1
Arabidopsis thaliana (thale cress)	GGT1	NP_195674.2

Gene Ontology
Bibliography

Related articles in PubMed

The human gamma-glutamyltransferase gene family.
Heisterkamp N, Groffen J, Warburton D, Sneddon TP
Human genetics123(4)321-32(2008 May)

An intronic promoter controls the expression of truncated human gamma-glutamyltransferase mRNAs.
Leh H, Chikhi N, Ichino K, Guella?n G, Wellman M, Siest G, Visvikis A
FEBS letters434(1-2)51-6(1998 Aug)

Expression of multiple gamma-glutamyltransferase genes in man.
Courtay C, Heisterkamp N, Siest G, Groffen J
The Biochemical journal297 ( Pt 3)503-8(1994 Feb)

Human lung expresses unique gamma-glutamyl transpeptidase transcripts.
Wetmore LA, Gerard C, Drazen JM
Proceedings of the National Academy of Sciences of the United States of America90(16)7461-5(1993 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High initial GGT concentration and increases in GGT concentration over time should be considered independent predictors of and to have a combined effect on incident metabolic syndrome.
Title: Combined Effect of Initial and Longitudinal Increases in ?-Glutamyltransferase on Incident Metabolic Syndrome: ARIRANG Study.

The structure of DON-bound hGGT1 has led to the discovery of a new mechanism of inactivation by DON that differs from its inactivation of other glutamine metabolizing enzymes, and insight into the activation of the catalytic nucleophile that initiates the hGGT1 reaction.
Title: Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation.

Study demonstrated that the combined effect of serum GGT and uric acid is associated with a diabetes risk in Korean women and that the use of the measurements of a combination of GGT and uric acid appears to have an additional benefit in the prediction of the future development of diabetes
Title: Combined effect of serum gamma-glutamyltransferase and uric acid on incidence of diabetes mellitus: A longitudinal study.

Preoperative GGT can serve as an independent prognostic biomarker of nonmetastatic renal cell carcinoma patients with venous tumor thrombus.
Title: Preoperative Gamma-Glutamyltransferase Is Associated with Cancer-Specific Survival and Recurrence-Free Survival of Nonmetastatic Renal Cell Carcinoma with Venous Tumor Thrombus.

gamma-glutamyltransferase may have a role in nasopharyngeal carcinoma
Title: Prognostic impact of pretherapeutic gamma-glutamyltransferase on patients with nasopharyngeal carcinoma.

The following GGT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GGT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16783	NM_013421.3 Latest version!	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16783	NM_013430.2 Latest version!	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16783	NM_001288833.2 Latest version!	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu16783	NM_001288833.1	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16783	NM_013421.2	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GGT1 ( NM_001288833.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275762.1 Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 6, mRNA.

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CloneID	OHu16783
Clone ID Related Accession (Same CDS sequence)	NM_001288833.1 , NM_001288833.2 , NM_013421.2 , NM_013430.2 , NM_013421.3
Accession Version	NM_001288833.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	glutathione hydrolase 1 proenzyme precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD625024.1, HY003521.1, BC035341.1, L20494.1 and BM673976.1. On Jan 8, 2014 this sequence version replaced XM_005261552.1. Transcript Variant: This variant (6) represents the longest transcript. Variants 2, 3, and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035341.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275762.1
CDS	800..2509
Translation	MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

Target ORF information:

RefSeq Version	NM_001288833.1
Organism	Homo sapiens(human)
Definition	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288833.1

ORF Insert Sequence:

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GGT1 ( NM_001288833.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275762.1 Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu16783
Clone ID Related Accession (Same CDS sequence)	NM_001288833.1 , NM_001288833.2 , NM_013421.2 , NM_013430.2 , NM_013421.3
Accession Version	NM_001288833.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-20
Organism	Homo sapiens(human)
Product	glutathione hydrolase 1 proenzyme precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD625024.1, HY003521.1, BC035341.1 and L20494.1. On Nov 22, 2018 this sequence version replaced NM_001288833.1. Transcript Variant: This variant (6) represents the longest transcript. Variants 2, 3, and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035341.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000400382.6/ ENSP00000383232.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275762.1
CDS	764..2473
Translation	MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

Target ORF information:

RefSeq Version	NM_001288833.2
Organism	Homo sapiens(human)
Definition	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288833.2

ORF Insert Sequence:

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GGT1 ( NM_013421.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_038265.2 Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 2, mRNA.

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CloneID	OHu16783
Clone ID Related Accession (Same CDS sequence)	NM_001288833.1 , NM_001288833.2 , NM_013421.2 , NM_013430.2 , NM_013421.3
Accession Version	NM_013421.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	glutathione hydrolase 1 proenzyme precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD625024.1, HY003521.1, L20494.1, J04131.1, BC025927.1 and BM673976.1. On or before Jan 8, 2014 this sequence version replaced XM_005261553.1, NM_013421.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 6. Variants 2, 3, and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J04131.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038265.2
CDS	728..2437
Translation	MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

Target ORF information:

RefSeq Version	NM_013421.2
Organism	Homo sapiens(human)
Definition	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013421.2

ORF Insert Sequence:

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GGT1 ( NM_013430.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_038347.2 Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16783
Clone ID Related Accession (Same CDS sequence)	NM_001288833.1 , NM_001288833.2 , NM_013421.2 , NM_013430.2 , NM_013421.3
Accession Version	NM_013430.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-20
Organism	Homo sapiens(human)
Product	glutathione hydrolase 1 proenzyme precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M24903.1, BU164348.1, BC025927.1 and BM673976.1. This sequence is a reference standard in the RefSeqGene project. On Aug 30, 2005 this sequence version replaced NM_013430.1. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 6. Variants 2, 3, and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M24903.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038347.2
CDS	488..2197
Translation	MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

Target ORF information:

RefSeq Version	NM_013430.2
Organism	Homo sapiens(human)
Definition	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013430.2

ORF Insert Sequence:

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GGT1 ( NM_013421.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_038265.2 Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16783
Clone ID Related Accession (Same CDS sequence)	NM_001288833.1 , NM_001288833.2 , NM_013421.2 , NM_013430.2 , NM_013421.3
Accession Version	NM_013421.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-20
Organism	Homo sapiens(human)
Product	glutathione hydrolase 1 proenzyme precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD625024.1, HY003521.1, L20494.1, J04131.1 and BC025927.1. On May 31, 2019 this sequence version replaced NM_013421.2. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 6. Variants 2, 3, and 6 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J04131.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038265.2
CDS	692..2401
Translation	MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

Target ORF information:

RefSeq Version	NM_013421.3
Organism	Homo sapiens(human)
Definition	Homo sapiens gamma-glutamyltransferase 1 (GGT1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013421.3

ORF Insert Sequence:

ATGAAGAAGA AGTTAGTGGT GCTGGGCCTG CTGGCCGTGG TCCTGGTGCT GGTCATTGTC 
GGCCTCTGTC TCTGGCTGCC CTCAGCCTCC AAGGAACCTG ACAACCATGT GTACACCAGG 
GCTGCCGTGG CCGCGGATGC CAAGCAGTGC TCGAAGATTG GGAGGGATGC ACTGCGGGAC 
GGTGGCTCTG CGGTGGATGC AGCCATTGCA GCCCTGTTGT GTGTGGGGCT CATGAATGCC 
CACAGCATGG GCATCGGGGG TGGCCTCTTC CTCACCATCT ACAACAGCAC CACACGAAAA 
GCTGAGGTCA TCAACGCCCG CGAGGTGGCC CCCAGGCTGG CCTTTGCCAC CATGTTCAAC 
AGCTCGGAGC AGTCCCAGAA GGGGGGGCTG TCGGTGGCGG TGCCTGGGGA GATCCGAGGC 
TATGAGCTGG CACACCAGCG GCATGGGCGG CTGCCCTGGG CTCGCCTCTT CCAGCCCAGC 
ATCCAGCTGG CCCGCCAGGG CTTCCCCGTG GGCAAGGGCT TGGCGGCAGC CCTGGAAAAC 
AAGCGGACCG TCATCGAGCA GCAGCCTGTC TTGTGTGAGG TGTTCTGCCG GGATAGAAAG 
GTGCTTCGGG AGGGGGAGAG ACTGACCCTG CCGCAGCTGG CTGACACCTA CGAGACGCTG 
GCCATCGAGG GTGCCCAGGC CTTCTACAAC GGCAGCCTCA CGGCCCAGAT TGTGAAGGAC 
ATCCAGGCGG CCGGGGGCAT TGTGACAGCT GAGGACCTGA ACAACTACCG TGCTGAGCTG 
ATCGAGCACC CGCTGAACAT CAGCCTGGGA GACGTGGTGC TGTACATGCC CAGTGCGCCG 
CTCAGCGGGC CCGTGCTGGC CCTCATCCTC AACATCCTCA AAGGGTACAA CTTCTCCCGG 
GAGAGCGTGG AGAGCCCCGA GCAGAAGGGC CTGACGTACC ACCGCATCGT AGAGGCTTTC 
CGGTTTGCCT ACGCCAAGAG GACCCTGCTT GGGGACCCCA AGTTTGTGGA TGTGACTGAG 
GTGGTCCGCA ACATGACCTC CGAGTTCTTC GCTGCCCAGC TCCGGGCCCA GATCTCTGAC 
GACACCACTC ACCCGATCTC CTACTACAAG CCCGAGTTCT ACACGCCGGA TGACGGGGGC 
ACTGCTCACC TGTCTGTCGT CGCAGAGGAC GGCAGTGCTG TGTCCGCCAC CAGCACCATC 
AACCTCTACT TTGGCTCCAA GGTCCGCTCC CCGGTCAGCG GGATCCTGTT CAATAATGAA 
ATGGACGACT TCAGCTCTCC CAGCATCACC AACGAGTTTG GGGTACCCCC CTCACCTGCC 
AATTTCATCC AGCCAGGGAA GCAGCCGCTC TCGTCCATGT GCCCGACGAT CATGGTGGGC 
CAGGACGGCC AGGTCCGGAT GGTGGTGGGA GCTGCTGGGG GCACACAGAT CACCACGGCC 
ACTGCACTGG CCATCATCTA CAACCTCTGG TTCGGCTATG ACGTGAAGCG GGCCGTGGAG 
GAGCCCCGGC TGCACAACCA GCTTCTGCCC AACGTCACGA CAGTGGAGAG AAACATTGAC 
CAGGCAGTGA CTGCAGCCCT GGAGACCCGG CACCATCACA CCCAGATCGC GTCCACCTTC 
ATCGCTGTGG TGCAAGCCAT CGTCCGCACG GCTGGTGGCT GGGCAGCTGC CTCGGACTCC 
AGGAAAGGCG GGGAGCCTGC CGGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The human gamma-glutamyltransferase gene family.
Human genetics123(4)321-32(2008 May)
Heisterkamp N,Groffen J,Warburton D,Sneddon TP

An intronic promoter controls the expression of truncated human gamma-glutamyltransferase mRNAs.
FEBS letters434(1-2)51-6(1998 Aug)
Leh H,Chikhi N,Ichino K,Guella?n G,Wellman M,Siest G,Visvikis A

Expression of multiple gamma-glutamyltransferase genes in man.
The Biochemical journal297 ( Pt 3)503-8(1994 Feb)
Courtay C,Heisterkamp N,Siest G,Groffen J

Human lung expresses unique gamma-glutamyl transpeptidase transcripts.
Proceedings of the National Academy of Sciences of the United States of America90(16)7461-5(1993 Aug)
Wetmore LA,Gerard C,Drazen JM

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GGT1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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