DAOA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DAOA
Entrez Gene ID	267012
Full Name	D-amino acid oxidase activator
Synonyms	LG72,SG72
General protein information	Preferred Names D-amino acid oxidase activator Names D-amino acid oxidase activator G72 transcript schizophrenia- and bipolar disorder-associated protein G72
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q33.2\|13q34
Summary	This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011].
Disorder MIM:	607408
Disorder Html:	{Schizophrenia}, 181500 (2)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005254042.1	XP_005254099.1	D-amino acid oxidase activator isoform X1
NM_001161812.1	NP_001155284.1	D-amino acid oxidase activator isoform 2
NM_001161814.1	NP_001155286.1	D-amino acid oxidase activator isoform 3
NM_172370.4	NP_758958.3	D-amino acid oxidase activator isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DAOA	XP_003954467.1
Homo sapiens (human)	DAOA	NP_758958.3

Gene Ontology
Bibliography

Related articles in PubMed

The interaction of NOS1AP, DISC1, DAOA, and GSK3B confers susceptibility of early-onset schizophrenia in Chinese Han population.
Hu G, Yang C, Zhao L, Fan Y, Lv Q, Zhao J, Zhu M, Guo X, Bao C, Xu A, Jie Y, Jiang Y, Zhang C, Yu S, Wang Z, Li Z, Yi Z
Progress in neuro-psychopharmacology & biological psychiatry81187-193(2018 Feb)

The DAOA gene is associated with schizophrenia in the Taiwanese population.
Chu CS, Chow PC, Cohen-Woods S, Gaysina D, Tang KY, McGuffin P
Psychiatry research252201-207(2017 Jun)

Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility.
Sacchi S, Cappelletti P, Pirone L, Smaldone G, Pedone E, Pollegioni L
FEBS letters591(4)646-655(2017 Feb)

pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: effect on schizophrenia susceptibility.
Sacchi S, Bernasconi M, Martineau M, Mothet JP, Ruzzene M, Pilone MS, Pollegioni L, Molla G
The Journal of biological chemistry283(32)22244-56(2008 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In SNP-based single locus association analyses, the rs778292 in the DAOA gene showed significant association with schizophrenia. Additionally, a three-SNP haplotype (rs778292-rs3918342-rs1421292) in the DAOA gene were observed to be significantly associated with schizophrenia in a Taiwanese population.
Title: The DAOA gene is associated with schizophrenia in the Taiwanese population.

We suggest that serum G72 protein levels may represent a candidate biomarker for schizophrenia and have confirmed the results of the previous preliminary study.
Title: Increased serum G72 protein levels in patients with schizophrenia: a potential candidate biomarker.

Data show that the R30K D-amino acid oxidase activator pLG72 is significantly more prone to degradation than the R30 and the K62E variants in a cell system.
Title: Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility.

Studies successfully predicted the structures of the N- and C-terminal domains (ND and CD, respectively) of G72.
Title: Structure models of G72, the product of a susceptibility gene to schizophrenia.

pLG72 interacts with neosynthesized d-amino acid oxidase (hDAAO), promoting its inactivation and degradation. In this work, we used low-resolution techniques to characterize the surface topology of the hDAAO-pLG72 complex.
Title: Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction.

The following DAOA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DAOA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15943	NM_172370.4 Latest version!	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18058	NM_001161814.1 Latest version!	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu15738	NM_001161812.1 Latest version!	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu47377	XM_005254042.1 Latest version!	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DAOA ( NM_172370.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_758958.3 Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15943
Clone ID Related Accession (Same CDS sequence)	NM_172370.4
Accession Version	NM_172370.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	D-amino acid oxidase activator isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY138547.1, BC121091.1 and AY138546.1. On Jun 20, 2013 this sequence version replaced NM_172370.3. Transcript Variant: This variant (1) encodes the longest isoform (1). CCDS Note: This CCDS ID represents the protein described in PMIDs: 12364586 and 14966479. This transcript is supported by AY138546.1. It should be noted this transcript is predicted to undergo nonsense-mediated mRNA decay (NMD). However, the protein is represented because it was detected endogenously in PMID: 18544534. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY138546.1, BC121091.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: PMID: 18544534 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END##

ATGCTGGAAA AGCTGATGGG TGCTGATTCT CTCCAGCTTT TCAGATCCAG ATATACATTG 
GGTAAAATCT ACTTCATAGG TTTTCAAAGG AGCATTCTTC TGAGCAAATC TGAAAACTCT 
CTAAACTCTA TTGCAAAGGA GACAGAAGAA GGAAGAGAGA CGGTAACAAG GAAAGAAGGA 
TGGAAGAGAA GGCATGAGGA CGGCTATTTG GAAATGGCAC AGAGGCATTT ACAGAGATCA 
TTATGTCCTT GGGTCTCTTA CCTTCCTCAG CCCTATGCAG AGCTTGAAGA AGTAAGCAGC 
CATGTTGGAA AAGTCTTCAT GGCAAGAAAC TATGAGTTCC TTGCCTATGA GGCCTCTAAG 
GACCGCAGGC AGCCTCTAGA ACGAATGTGG ACCTGCAACT ACAACCAGCA AAAAGACCAG 
TCATGCAACC ACAAGGAAAT AACTTCTACC AAAGCTGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758958.3
CDS	74..535
Translation	MLEKLMGADSLQLFRSRYTLGKIYFIGFQRSILLSKSENSLNSIAKETEEGRETVTRKEGWKRRHEDGYLEMAQRHLQRSLCPWVSYLPQPYAELEEVSSHVGKVFMARNYEFLAYEASKDRRQPLERMWTCNYNQQKDQSCNHKEITSTKAE

Target ORF information:

RefSeq Version	NM_172370.4
Organism	Homo sapiens(human)
Definition	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172370.4

ORF Insert Sequence:

ATGCTGGAAA AGCTGATGGG TGCTGATTCT CTCCAGCTTT TCAGATCCAG ATATACATTG 
GGTAAAATCT ACTTCATAGG TTTTCAAAGG AGCATTCTTC TGAGCAAATC TGAAAACTCT 
CTAAACTCTA TTGCAAAGGA GACAGAAGAA GGAAGAGAGA CGGTAACAAG GAAAGAAGGA 
TGGAAGAGAA GGCATGAGGA CGGCTATTTG GAAATGGCAC AGAGGCATTT ACAGAGATCA 
TTATGTCCTT GGGTCTCTTA CCTTCCTCAG CCCTATGCAG AGCTTGAAGA AGTAAGCAGC 
CATGTTGGAA AAGTCTTCAT GGCAAGAAAC TATGAGTTCC TTGCCTATGA GGCCTCTAAG 
GACCGCAGGC AGCCTCTAGA ACGAATGTGG ACCTGCAACT ACAACCAGCA AAAAGACCAG 
TCATGCAACC ACAAGGAAAT AACTTCTACC AAAGCTGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DAOA ( NM_001161814.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001155286.1 Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu18058
Clone ID Related Accession (Same CDS sequence)	NM_001161814.1
Accession Version	NM_001161814.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 249bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-01
Organism	Homo sapiens(human)
Product	D-amino acid oxidase activator isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY138547.1 and AY170469.2. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (3) has an alternate 5' exon and an additional segment in the 5' coding region, as compared to variant 1, which results in a downstream AUG start codon. The resulting isoform (3) is shorter and has a different N-terminus, as compared to isoform 1. CCDS Note: This CCDS ID represents the protein described in PMIDs: 12364586 and 14966479. This transcript is supported by AY170469.2. It should be noted this transcript is predicted to undergo nonsense-mediated mRNA decay (NMD). However, the protein is represented because it was detected endogenously in PMID: 18544534. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY138547.1, AY170469.2 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred ##RefSeq-Attributes-END##

ATGGCACAGA GGCATTTACA GAGATCATTA TGTCCTTGGG TCTCTTACCT TCCTCAGCCC 
TATGCAGAGC TTGAAGAAGT AAGCAGCCAT GTTGGAAAAG TCTTCATGGC AAGAAACTAT 
GAGTTCCTTG CCTATGAGGC CTCTAAGGAC CGCAGGCAGC CTCTAGAACG AATGTGGACC 
TGCAACTACA ACCAGCAAAA AGACCAGTCA TGCAACCACA AGGAAATAAC TTCTACCAAA 
GCTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155286.1
CDS	527..775
Translation	MAQRHLQRSLCPWVSYLPQPYAELEEVSSHVGKVFMARNYEFLAYEASKDRRQPLERMWTCNYNQQKDQSCNHKEITSTKAE

Target ORF information:

RefSeq Version	NM_001161814.1
Organism	Homo sapiens(human)
Definition	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161814.1

ORF Insert Sequence:

ATGGCACAGA GGCATTTACA GAGATCATTA TGTCCTTGGG TCTCTTACCT TCCTCAGCCC 
TATGCAGAGC TTGAAGAAGT AAGCAGCCAT GTTGGAAAAG TCTTCATGGC AAGAAACTAT 
GAGTTCCTTG CCTATGAGGC CTCTAAGGAC CGCAGGCAGC CTCTAGAACG AATGTGGACC 
TGCAACTACA ACCAGCAAAA AGACCAGTCA TGCAACCACA AGGAAATAAC TTCTACCAAA 
GCTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DAOA ( NM_001161812.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001155284.1 Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15738
Clone ID Related Accession (Same CDS sequence)	NM_001161812.1
Accession Version	NM_001161812.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-01
Organism	Homo sapiens(human)
Product	D-amino acid oxidase activator isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY138547.1 and DQ386870.1. Transcript Variant: This variant (2) has additional segments in the 5' and 3' coding regions, as compared to variant 1, which results in a downstream AUG start codon. The resulting isoform (2) is shorter and has a different N-terminus, as compared to isoform 1. CCDS Note: This CCDS ID represents the protein described in PMIDs: 12364586 and 14966479. This transcript is supported by AY170469.2. It should be noted this transcript is predicted to undergo nonsense-mediated mRNA decay (NMD). However, the protein is represented because it was detected endogenously in PMID: 18544534. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ386870.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred ##RefSeq-Attributes-END##

ATGAGGACGG CTATTTGGAA ATGGCACAGA GGCATTTACA GAGATCATTA TGTCCTTGGG 
TCTCTTACCT TCCTCAGCCC TATGCAGAGA GCTGGGACTT CTAACCAATG GAACATGGGA 
AAGGTGATGA CACTTGACTC CGGTGATGAG GTTACCTTTC ACAAGACCTG GCCAACTGAG 
ACCGGATCTC CTTACAGGCT TGAAGAAGTA AGCAGCCATG TTGGAAAAGT CTTCATGGCA 
AGAAACTATG AGTTCCTTGC CTATGAGGCC TCTAAGGACC GCAGGCAGCC TCTAGAACGA 
ATGTGGACCT GCAACTACAA CCAGCAAAAA GACCAGTCAT GCAACCACAA GGAAATAACT 
TCTACCAAAG CTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155284.1
CDS	313..690
Translation	MRTAIWKWHRGIYRDHYVLGSLTFLSPMQRAGTSNQWNMGKVMTLDSGDEVTFHKTWPTETGSPYRLEEVSSHVGKVFMARNYEFLAYEASKDRRQPLERMWTCNYNQQKDQSCNHKEITSTKAE

Target ORF information:

RefSeq Version	NM_001161812.1
Organism	Homo sapiens(human)
Definition	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161812.1

ORF Insert Sequence:

ATGAGGACGG CTATTTGGAA ATGGCACAGA GGCATTTACA GAGATCATTA TGTCCTTGGG 
TCTCTTACCT TCCTCAGCCC TATGCAGAGA GCTGGGACTT CTAACCAATG GAACATGGGA 
AAGGTGATGA CACTTGACTC CGGTGATGAG GTTACCTTTC ACAAGACCTG GCCAACTGAG 
ACCGGATCTC CTTACAGGCT TGAAGAAGTA AGCAGCCATG TTGGAAAAGT CTTCATGGCA 
AGAAACTATG AGTTCCTTGC CTATGAGGCC TCTAAGGACC GCAGGCAGCC TCTAGAACGA 
ATGTGGACCT GCAACTACAA CCAGCAAAAA GACCAGTCAT GCAACCACAA GGAAATAACT 
TCTACCAAAG CTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DAOA ( XM_005254042.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005254099.1 Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu47377
Clone ID Related Accession (Same CDS sequence)	XM_005254042.1
Accession Version	XM_005254042.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	D-amino acid oxidase activator isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGAAA AGCTGATGGG TGCTGATTCT CTCCAGCTTT TCAGATCCAG ATATACATTG 
GGTAAAATCT ACTTCATAGG TTTTCAAAGG AGCATTCTTC TGAGCAAATC TGAAAACTCT 
CTAAACTCTA TTGCAAAGGA GACAGAAGAA GGAAGAGAGA CGGTAACAAG GAAAGAAGGA 
TGGAAGAGAA GGCATGAGGA CGGCTATTTG GAAATGGCAC AGAGGCATTT ACAGAGATCA 
TTATGTCCTT GGGTCTCTTA CCTTCCTCAG CCCTATGCAG AACATTCCAA GGTGATTCTA 
AATGGCAATT TGCACTGTCA TTTTAAAAGA ATTTCTCAGA TATTTGCTGG GCACTTTATG 
GAAGGAGACA CTGAGGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005254099.1
CDS	272..652
Translation	MLEKLMGADSLQLFRSRYTLGKIYFIGFQRSILLSKSENSLNSIAKETEEGRETVTRKEGWKRRHEDGYLEMAQRHLQRSLCPWVSYLPQPYAEHSKVILNGNLHCHFKRISQIFAGHFMEGDTEA

Target ORF information:

RefSeq Version	XM_005254042.1
Organism	Homo sapiens(human)
Definition	Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005254042.1

ORF Insert Sequence:

ATGCTGGAAA AGCTGATGGG TGCTGATTCT CTCCAGCTTT TCAGATCCAG ATATACATTG 
GGTAAAATCT ACTTCATAGG TTTTCAAAGG AGCATTCTTC TGAGCAAATC TGAAAACTCT 
CTAAACTCTA TTGCAAAGGA GACAGAAGAA GGAAGAGAGA CGGTAACAAG GAAAGAAGGA 
TGGAAGAGAA GGCATGAGGA CGGCTATTTG GAAATGGCAC AGAGGCATTT ACAGAGATCA 
TTATGTCCTT GGGTCTCTTA CCTTCCTCAG CCCTATGCAG AACATTCCAA GGTGATTCTA 
AATGGCAATT TGCACTGTCA TTTTAAAAGA ATTTCTCAGA TATTTGCTGG GCACTTTATG 
GAAGGAGACA CTGAGGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The interaction of NOS1AP, DISC1, DAOA, and GSK3B confers susceptibility of early-onset schizophrenia in Chinese Han population.
Progress in neuro-psychopharmacology & biological psychiatry81187-193(2018 Feb)
Hu G,Yang C,Zhao L,Fan Y,Lv Q,Zhao J,Zhu M,Guo X,Bao C,Xu A,Jie Y,Jiang Y,Zhang C,Yu S,Wang Z,Li Z,Yi Z

The DAOA gene is associated with schizophrenia in the Taiwanese population.
Psychiatry research252201-207(2017 Jun)
Chu CS,Chow PC,Cohen-Woods S,Gaysina D,Tang KY,McGuffin P

Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility.
FEBS letters591(4)646-655(2017 Feb)
Sacchi S,Cappelletti P,Pirone L,Smaldone G,Pedone E,Pollegioni L

pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: effect on schizophrenia susceptibility.
The Journal of biological chemistry283(32)22244-56(2008 Aug)
Sacchi S,Bernasconi M,Martineau M,Mothet JP,Ruzzene M,Pilone MS,Pollegioni L,Molla G

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DAOA cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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