ITGB1BP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITGB1BP2
Entrez Gene ID	26548
Full Name	integrin subunit beta 1 binding protein 2
Synonyms	CHORDC3,ITGB1BP,MELUSIN,MSTP015
General protein information	Preferred Names integrin subunit beta 1 binding protein 2 Names integrin beta-1-binding protein 2 integrin beta 1 binding protein (melusin) 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq13.1
Summary	This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. [provided by RefSeq, May 2017].
Disorder MIM:	300332

mRNA and Protein(s)

mRNA	Protein	Name
NM_012278.3	NP_036410.1	integrin beta-1-binding protein 2 isoform 1
NM_001303277.3	NP_001290206.1	integrin beta-1-binding protein 2 isoform 2
XM_017029405.1	XP_016884894.1	integrin beta-1-binding protein 2 isoform X1
NM_001303277.2	NP_001290206.1	integrin beta-1-binding protein 2 isoform 2
NM_012278.2	NP_036410.1	integrin beta-1-binding protein 2 isoform 1
NM_001303277.1	NP_001290206.1	integrin beta-1-binding protein 2 isoform 2
NM_012278.4	NP_036410.1	integrin beta-1-binding protein 2 isoform 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	ITGB1BP2	XP_420200.3
Homo sapiens (human)	ITGB1BP2	NP_036410.1
Pan troglodytes (chimpanzee)	ITGB1BP2	XP_521119.1
	ITGB1BP2	XP_001091670.1
Rattus norvegicus (Norway rat)	Itgb1bp2	NP_001101715.1
Canis lupus familiaris (dog)	ITGB1BP2	XP_538074.2
Bos taurus (cattle)	ITGB1BP2	NP_001192661.1
Mus musculus (house mouse)	Itgb1bp2	NP_038740.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Taipale M, Tucker G, Peng J, Krykbaeva I, Lin ZY, Larsen B, Choi H, Berger B, Gingras AC, Lindquist S
Cell158(2)434-448(2014 Jul)

Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy.
Ruppert V, Meyer T, Richter A, Maisch B, Pankuweit S,
Gene512(2)206-10(2013 Jan)

Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1.
Hong TJ, Kim S, Wi AR, Lee P, Kang M, Jeong JH, Hahn JS
The Journal of biological chemistry288(1)215-22(2013 Jan)

Morgana and melusin: two fairies chaperoning signal transduction.
Ferretti R, Sbroggi? M, Di Savino A, Fusella F, Bertero A, Michowski W, Tarone G, Brancaccio M
Cell cycle (Georgetown, Tex.)10(21)3678-83(2011 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy
Title: Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy.

Chp-1 and melusin can interact with cochaperones PP5 and Sgt1 and with each other in an ATP-dependent manner
Title: Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1.

The altered melusin pathways and CDC42 parallel the cardiac function progression during cardiac remodeling post-MI.
Title: Altered melusin pathways involved in cardiac remodeling following acute myocardial infarction.

Observational study of gene-disease association. (HuGE Navigator)
Title: Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients.

Studies in mouse show that melusin prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress.
Title: Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload.

The following ITGB1BP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITGB1BP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu54146	NM_001303277.3 Latest version!	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu66964	NM_012278.4 Latest version!	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$202.30 $289.00
OHu99237	XM_017029405.1 Latest version!	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu54146	NM_001303277.2	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu66964	NM_012278.2	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$202.30 $289.00
OHu54146	NM_001303277.1	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu66964	NM_012278.3	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$202.30 $289.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITGB1BP2 ( NM_001303277.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290206.1 Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu54146
Clone ID Related Accession (Same CDS sequence)	NM_001303277.3 , NM_001303277.2 , NM_001303277.1
Accession Version	NM_001303277.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	integrin beta-1-binding protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP372847.1 and AF110225.1. On May 31, 2019 this sequence version replaced NM_001303277.2. Transcript Variant: This variant (2) lacks three exons in the 5' end, compared to variant 1. This difference results in translation initiation at a downstream, in-frame start codon and an isoform (2) with a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.97922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATTGG AACAGAAGGA ATTAGACCAG GAACCTGGGG CAGGACTTGA CAGTCTGATC 
CGGACTGGTT CCAGCTGCCA GAACCCAGGA TGTGATGCTG TTTACCAAGG CCCTGAGAGT 
GATGCTACTC CATGTACCTA CCACCCAGGA GCACCCCGAT TCCATGAGGG GATGAAGTCT 
TGGAGCTGTT GTGGCATCCA GACCCTGGAT TTTGGGGCAT TCTTGGCACA ACCAGGGTGC 
AGAGTCGGTA GACATGACTG GGGGAAGCAG CTCCCAGCAT CTTGCCGCCA TGATTGGCAC 
CAGACAGATT CCTTAGTAGT GGTGACTGTA TATGGCCAGA TTCCACTTCC TGCGTTTAAC 
TGGGTGAAGG CCAGTCAAAC TGAGCTTCAT GTCCACATTG TCTTTGATGG TAACCGTGTG 
TTCCAAGCAC AGATGAAGCT CTGGGGGGTC ATAAACGTGG AGCAGAGCTC TGTCTTCTTG 
ATGCCATCTC GGGTTGAAAT CTCCCTGGTC AAGGCTGACC CAGGATCCTG GGCCCAGCTG 
GAGCACCCTG ATGCACTAGC TAAGAAGGCT AGGGCAGGGG TTGTGTTAGA GATGGATGAG 
GAAGAATCTG ACGATTCAGA TGATGATCTG AGCTGGACAG AGGAGGAGGA AGAGGAGGAA 
GCAATGGGGG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290206.1
CDS	174..848
Translation	MALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE

Target ORF information:

RefSeq Version	NM_001303277.3
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303277.3

ORF Insert Sequence:

ATGGCATTGG AACAGAAGGA ATTAGACCAG GAACCTGGGG CAGGACTTGA CAGTCTGATC 
CGGACTGGTT CCAGCTGCCA GAACCCAGGA TGTGATGCTG TTTACCAAGG CCCTGAGAGT 
GATGCTACTC CATGTACCTA CCACCCAGGA GCACCCCGAT TCCATGAGGG GATGAAGTCT 
TGGAGCTGTT GTGGCATCCA GACCCTGGAT TTTGGGGCAT TCTTGGCACA ACCAGGGTGC 
AGAGTCGGTA GACATGACTG GGGGAAGCAG CTCCCAGCAT CTTGCCGCCA TGATTGGCAC 
CAGACAGATT CCTTAGTAGT GGTGACTGTA TATGGCCAGA TTCCACTTCC TGCGTTTAAC 
TGGGTGAAGG CCAGTCAAAC TGAGCTTCAT GTCCACATTG TCTTTGATGG TAACCGTGTG 
TTCCAAGCAC AGATGAAGCT CTGGGGGGTC ATAAACGTGG AGCAGAGCTC TGTCTTCTTG 
ATGCCATCTC GGGTTGAAAT CTCCCTGGTC AAGGCTGACC CAGGATCCTG GGCCCAGCTG 
GAGCACCCTG ATGCACTAGC TAAGAAGGCT AGGGCAGGGG TTGTGTTAGA GATGGATGAG 
GAAGAATCTG ACGATTCAGA TGATGATCTG AGCTGGACAG AGGAGGAGGA AGAGGAGGAA 
GCAATGGGGG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGB1BP2 ( NM_001303277.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290206.1 Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu54146
Clone ID Related Accession (Same CDS sequence)	NM_001303277.3 , NM_001303277.2 , NM_001303277.1
Accession Version	NM_001303277.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	integrin beta-1-binding protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA249829.1, DA895605.1, BP372847.1 and AF110225.1. On May 17, 2017 this sequence version replaced NM_001303277.1. Transcript Variant: This variant (2) lacks three exons in the 5' end, compared to variant 1. This difference results in translation initiation at a downstream, in-frame start codon and an isoform (2) with a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.97922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATTGG AACAGAAGGA ATTAGACCAG GAACCTGGGG CAGGACTTGA CAGTCTGATC 
CGGACTGGTT CCAGCTGCCA GAACCCAGGA TGTGATGCTG TTTACCAAGG CCCTGAGAGT 
GATGCTACTC CATGTACCTA CCACCCAGGA GCACCCCGAT TCCATGAGGG GATGAAGTCT 
TGGAGCTGTT GTGGCATCCA GACCCTGGAT TTTGGGGCAT TCTTGGCACA ACCAGGGTGC 
AGAGTCGGTA GACATGACTG GGGGAAGCAG CTCCCAGCAT CTTGCCGCCA TGATTGGCAC 
CAGACAGATT CCTTAGTAGT GGTGACTGTA TATGGCCAGA TTCCACTTCC TGCGTTTAAC 
TGGGTGAAGG CCAGTCAAAC TGAGCTTCAT GTCCACATTG TCTTTGATGG TAACCGTGTG 
TTCCAAGCAC AGATGAAGCT CTGGGGGGTC ATAAACGTGG AGCAGAGCTC TGTCTTCTTG 
ATGCCATCTC GGGTTGAAAT CTCCCTGGTC AAGGCTGACC CAGGATCCTG GGCCCAGCTG 
GAGCACCCTG ATGCACTAGC TAAGAAGGCT AGGGCAGGGG TTGTGTTAGA GATGGATGAG 
GAAGAATCTG ACGATTCAGA TGATGATCTG AGCTGGACAG AGGAGGAGGA AGAGGAGGAA 
GCAATGGGGG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290206.1
CDS	190..864
Translation	MALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE

Target ORF information:

RefSeq Version	NM_001303277.2
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303277.2

ORF Insert Sequence:

ATGGCATTGG AACAGAAGGA ATTAGACCAG GAACCTGGGG CAGGACTTGA CAGTCTGATC 
CGGACTGGTT CCAGCTGCCA GAACCCAGGA TGTGATGCTG TTTACCAAGG CCCTGAGAGT 
GATGCTACTC CATGTACCTA CCACCCAGGA GCACCCCGAT TCCATGAGGG GATGAAGTCT 
TGGAGCTGTT GTGGCATCCA GACCCTGGAT TTTGGGGCAT TCTTGGCACA ACCAGGGTGC 
AGAGTCGGTA GACATGACTG GGGGAAGCAG CTCCCAGCAT CTTGCCGCCA TGATTGGCAC 
CAGACAGATT CCTTAGTAGT GGTGACTGTA TATGGCCAGA TTCCACTTCC TGCGTTTAAC 
TGGGTGAAGG CCAGTCAAAC TGAGCTTCAT GTCCACATTG TCTTTGATGG TAACCGTGTG 
TTCCAAGCAC AGATGAAGCT CTGGGGGGTC ATAAACGTGG AGCAGAGCTC TGTCTTCTTG 
ATGCCATCTC GGGTTGAAAT CTCCCTGGTC AAGGCTGACC CAGGATCCTG GGCCCAGCTG 
GAGCACCCTG ATGCACTAGC TAAGAAGGCT AGGGCAGGGG TTGTGTTAGA GATGGATGAG 
GAAGAATCTG ACGATTCAGA TGATGATCTG AGCTGGACAG AGGAGGAGGA AGAGGAGGAA 
GCAATGGGGG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGB1BP2 ( NM_001303277.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290206.1 Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu54146
Clone ID Related Accession (Same CDS sequence)	NM_001303277.3 , NM_001303277.2 , NM_001303277.1
Accession Version	NM_001303277.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-22
Organism	Homo sapiens(Human)
Product	integrin beta-1-binding protein 2 isoform 2
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA895605.1, BP372847.1 and AF110225.1. On Dec 25, 2014 this sequence version replaced XM_005262255.2. Transcript Variant: This variant (2) lacks three exons in the 5' end, compared to variant 1. This difference results in translation initiation at a downstream, in-frame start codon and an isoform (2) with a shorter N-terminus, compared to isoform 1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATTGG AACAGAAGGA ATTAGACCAG GAACCTGGGG CAGGACTTGA CAGTCTGATC 
CGGACTGGTT CCAGCTGCCA GAACCCAGGA TGTGATGCTG TTTACCAAGG CCCTGAGAGT 
GATGCTACTC CATGTACCTA CCACCCAGGA GCACCCCGAT TCCATGAGGG GATGAAGTCT 
TGGAGCTGTT GTGGCATCCA GACCCTGGAT TTTGGGGCAT TCTTGGCACA ACCAGGGTGC 
AGAGTCGGTA GACATGACTG GGGGAAGCAG CTCCCAGCAT CTTGCCGCCA TGATTGGCAC 
CAGACAGATT CCTTAGTAGT GGTGACTGTA TATGGCCAGA TTCCACTTCC TGCGTTTAAC 
TGGGTGAAGG CCAGTCAAAC TGAGCTTCAT GTCCACATTG TCTTTGATGG TAACCGTGTG 
TTCCAAGCAC AGATGAAGCT CTGGGGGGTC ATAAACGTGG AGCAGAGCTC TGTCTTCTTG 
ATGCCATCTC GGGTTGAAAT CTCCCTGGTC AAGGCTGACC CAGGATCCTG GGCCCAGCTG 
GAGCACCCTG ATGCACTAGC TAAGAAGGCT AGGGCAGGGG TTGTGTTAGA GATGGATGAG 
GAAGAATCTG ACGATTCAGA TGATGATCTG AGCTGGACAG AGGAGGAGGA AGAGGAGGAA 
GCAATGGGGG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290206.1
CDS	176..850
Translation	MALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE

Target ORF information:

RefSeq Version	NM_001303277.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303277.1

ORF Insert Sequence:

ATGGCATTGG AACAGAAGGA ATTAGACCAG GAACCTGGGG CAGGACTTGA CAGTCTGATC 
CGGACTGGTT CCAGCTGCCA GAACCCAGGA TGTGATGCTG TTTACCAAGG CCCTGAGAGT 
GATGCTACTC CATGTACCTA CCACCCAGGA GCACCCCGAT TCCATGAGGG GATGAAGTCT 
TGGAGCTGTT GTGGCATCCA GACCCTGGAT TTTGGGGCAT TCTTGGCACA ACCAGGGTGC 
AGAGTCGGTA GACATGACTG GGGGAAGCAG CTCCCAGCAT CTTGCCGCCA TGATTGGCAC 
CAGACAGATT CCTTAGTAGT GGTGACTGTA TATGGCCAGA TTCCACTTCC TGCGTTTAAC 
TGGGTGAAGG CCAGTCAAAC TGAGCTTCAT GTCCACATTG TCTTTGATGG TAACCGTGTG 
TTCCAAGCAC AGATGAAGCT CTGGGGGGTC ATAAACGTGG AGCAGAGCTC TGTCTTCTTG 
ATGCCATCTC GGGTTGAAAT CTCCCTGGTC AAGGCTGACC CAGGATCCTG GGCCCAGCTG 
GAGCACCCTG ATGCACTAGC TAAGAAGGCT AGGGCAGGGG TTGTGTTAGA GATGGATGAG 
GAAGAATCTG ACGATTCAGA TGATGATCTG AGCTGGACAG AGGAGGAGGA AGAGGAGGAA 
GCAATGGGGG AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGB1BP2 ( NM_012278.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036410.1 Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu66964
Clone ID Related Accession (Same CDS sequence)	NM_012278.3 , NM_012278.2 , NM_012278.4
Accession Version	NM_012278.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	integrin beta-1-binding protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA249829.1, DA895605.1 and AF110225.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2017 this sequence version replaced NM_012278.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279847.726.1, AF140690.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTCTAC TCTGTCGTAA CAAAGGCTGT GGGCAGCACT TTGACCCTAA TACCAACCTT 
CCTGATTCCT GTTGCCATCA CCCTGGGGTC CCAATCTTCC ATGATGCACT TAAGGGTTGG 
TCCTGCTGCC GAAAGCGAAC TGTAGATTTC TCTGAGTTCT TAAACATCAA GGGCTGTACT 
ATGGGACCAC ACTGTGCTGA GAAGCTTCCT GAGGCCCCTC AACCTGAAGG CCCTGCTACA 
AGCAGTTCAC TTCAGGAGCA AAAACCTCTG AATGTGATTC CAAAGTCAGC AGAGACCTTG 
CGCCGGGAGA GGCCCAAGTC AGAGTTGCCT CTGAAGCTGC TGCCGCTAAA TATATCCCAA 
GCCCTGGAAA TGGCATTGGA ACAGAAGGAA TTAGACCAGG AACCTGGGGC AGGACTTGAC 
AGTCTGATCC GGACTGGTTC CAGCTGCCAG AACCCAGGAT GTGATGCTGT TTACCAAGGC 
CCTGAGAGTG ATGCTACTCC ATGTACCTAC CACCCAGGAG CACCCCGATT CCATGAGGGG 
ATGAAGTCTT GGAGCTGTTG TGGCATCCAG ACCCTGGATT TTGGGGCATT CTTGGCACAA 
CCAGGGTGCA GAGTCGGTAG ACATGACTGG GGGAAGCAGC TCCCAGCATC TTGCCGCCAT 
GATTGGCACC AGACAGATTC CTTAGTAGTG GTGACTGTAT ATGGCCAGAT TCCACTTCCT 
GCGTTTAACT GGGTGAAGGC CAGTCAAACT GAGCTTCATG TCCACATTGT CTTTGATGGT 
AACCGTGTGT TCCAAGCACA GATGAAGCTC TGGGGGGTCA TAAACGTGGA GCAGAGCTCT 
GTCTTCTTGA TGCCATCTCG GGTTGAAATC TCCCTGGTCA AGGCTGACCC AGGATCCTGG 
GCCCAGCTGG AGCACCCTGA TGCACTAGCT AAGAAGGCTA GGGCAGGGGT TGTGTTAGAG 
ATGGATGAGG AAGAATCTGA CGATTCAGAT GATGATCTGA GCTGGACAGA GGAGGAGGAA 
GAGGAGGAAG CAATGGGGGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036410.1
CDS	74..1117
Translation	MSLLCRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTMGPHCAEKLPEAPQPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQALEMALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE

Target ORF information:

RefSeq Version	NM_012278.3
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012278.3

ORF Insert Sequence:

ATGTCTCTAC TCTGTCGTAA CAAAGGCTGT GGGCAGCACT TTGACCCTAA TACCAACCTT 
CCTGATTCCT GTTGCCATCA CCCTGGGGTC CCAATCTTCC ATGATGCACT TAAGGGTTGG 
TCCTGCTGCC GAAAGCGAAC TGTAGATTTC TCTGAGTTCT TAAACATCAA GGGCTGTACT 
ATGGGACCAC ACTGTGCTGA GAAGCTTCCT GAGGCCCCTC AACCTGAAGG CCCTGCTACA 
AGCAGTTCAC TTCAGGAGCA AAAACCTCTG AATGTGATTC CAAAGTCAGC AGAGACCTTG 
CGCCGGGAGA GGCCCAAGTC AGAGTTGCCT CTGAAGCTGC TGCCGCTAAA TATATCCCAA 
GCCCTGGAAA TGGCATTGGA ACAGAAGGAA TTAGACCAGG AACCTGGGGC AGGACTTGAC 
AGTCTGATCC GGACTGGTTC CAGCTGCCAG AACCCAGGAT GTGATGCTGT TTACCAAGGC 
CCTGAGAGTG ATGCTACTCC ATGTACCTAC CACCCAGGAG CACCCCGATT CCATGAGGGG 
ATGAAGTCTT GGAGCTGTTG TGGCATCCAG ACCCTGGATT TTGGGGCATT CTTGGCACAA 
CCAGGGTGCA GAGTCGGTAG ACATGACTGG GGGAAGCAGC TCCCAGCATC TTGCCGCCAT 
GATTGGCACC AGACAGATTC CTTAGTAGTG GTGACTGTAT ATGGCCAGAT TCCACTTCCT 
GCGTTTAACT GGGTGAAGGC CAGTCAAACT GAGCTTCATG TCCACATTGT CTTTGATGGT 
AACCGTGTGT TCCAAGCACA GATGAAGCTC TGGGGGGTCA TAAACGTGGA GCAGAGCTCT 
GTCTTCTTGA TGCCATCTCG GGTTGAAATC TCCCTGGTCA AGGCTGACCC AGGATCCTGG 
GCCCAGCTGG AGCACCCTGA TGCACTAGCT AAGAAGGCTA GGGCAGGGGT TGTGTTAGAG 
ATGGATGAGG AAGAATCTGA CGATTCAGAT GATGATCTGA GCTGGACAGA GGAGGAGGAA 
GAGGAGGAAG CAATGGGGGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGB1BP2 ( NM_012278.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_036410.1 Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.

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CloneID	OHu66964
Clone ID Related Accession (Same CDS sequence)	NM_012278.3 , NM_012278.2 , NM_012278.4
Accession Version	NM_012278.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-22
Organism	Homo sapiens(Human)
Product	integrin beta-1-binding protein 2 isoform 1
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA895605.1 and AF110225.1. On Dec 25, 2014 this sequence version replaced NM_012278.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AF110225.1, AF140690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTCTAC TCTGTCGTAA CAAAGGCTGT GGGCAGCACT TTGACCCTAA TACCAACCTT 
CCTGATTCCT GTTGCCATCA CCCTGGGGTC CCAATCTTCC ATGATGCACT TAAGGGTTGG 
TCCTGCTGCC GAAAGCGAAC TGTAGATTTC TCTGAGTTCT TAAACATCAA GGGCTGTACT 
ATGGGACCAC ACTGTGCTGA GAAGCTTCCT GAGGCCCCTC AACCTGAAGG CCCTGCTACA 
AGCAGTTCAC TTCAGGAGCA AAAACCTCTG AATGTGATTC CAAAGTCAGC AGAGACCTTG 
CGCCGGGAGA GGCCCAAGTC AGAGTTGCCT CTGAAGCTGC TGCCGCTAAA TATATCCCAA 
GCCCTGGAAA TGGCATTGGA ACAGAAGGAA TTAGACCAGG AACCTGGGGC AGGACTTGAC 
AGTCTGATCC GGACTGGTTC CAGCTGCCAG AACCCAGGAT GTGATGCTGT TTACCAAGGC 
CCTGAGAGTG ATGCTACTCC ATGTACCTAC CACCCAGGAG CACCCCGATT CCATGAGGGG 
ATGAAGTCTT GGAGCTGTTG TGGCATCCAG ACCCTGGATT TTGGGGCATT CTTGGCACAA 
CCAGGGTGCA GAGTCGGTAG ACATGACTGG GGGAAGCAGC TCCCAGCATC TTGCCGCCAT 
GATTGGCACC AGACAGATTC CTTAGTAGTG GTGACTGTAT ATGGCCAGAT TCCACTTCCT 
GCGTTTAACT GGGTGAAGGC CAGTCAAACT GAGCTTCATG TCCACATTGT CTTTGATGGT 
AACCGTGTGT TCCAAGCACA GATGAAGCTC TGGGGGGTCA TAAACGTGGA GCAGAGCTCT 
GTCTTCTTGA TGCCATCTCG GGTTGAAATC TCCCTGGTCA AGGCTGACCC AGGATCCTGG 
GCCCAGCTGG AGCACCCTGA TGCACTAGCT AAGAAGGCTA GGGCAGGGGT TGTGTTAGAG 
ATGGATGAGG AAGAATCTGA CGATTCAGAT GATGATCTGA GCTGGACAGA GGAGGAGGAA 
GAGGAGGAAG CAATGGGGGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036410.1
CDS	60..1103
Translation	MSLLCRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTMGPHCAEKLPEAPQPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQALEMALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE

Target ORF information:

RefSeq Version	NM_012278.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012278.2

ORF Insert Sequence:

ATGTCTCTAC TCTGTCGTAA CAAAGGCTGT GGGCAGCACT TTGACCCTAA TACCAACCTT 
CCTGATTCCT GTTGCCATCA CCCTGGGGTC CCAATCTTCC ATGATGCACT TAAGGGTTGG 
TCCTGCTGCC GAAAGCGAAC TGTAGATTTC TCTGAGTTCT TAAACATCAA GGGCTGTACT 
ATGGGACCAC ACTGTGCTGA GAAGCTTCCT GAGGCCCCTC AACCTGAAGG CCCTGCTACA 
AGCAGTTCAC TTCAGGAGCA AAAACCTCTG AATGTGATTC CAAAGTCAGC AGAGACCTTG 
CGCCGGGAGA GGCCCAAGTC AGAGTTGCCT CTGAAGCTGC TGCCGCTAAA TATATCCCAA 
GCCCTGGAAA TGGCATTGGA ACAGAAGGAA TTAGACCAGG AACCTGGGGC AGGACTTGAC 
AGTCTGATCC GGACTGGTTC CAGCTGCCAG AACCCAGGAT GTGATGCTGT TTACCAAGGC 
CCTGAGAGTG ATGCTACTCC ATGTACCTAC CACCCAGGAG CACCCCGATT CCATGAGGGG 
ATGAAGTCTT GGAGCTGTTG TGGCATCCAG ACCCTGGATT TTGGGGCATT CTTGGCACAA 
CCAGGGTGCA GAGTCGGTAG ACATGACTGG GGGAAGCAGC TCCCAGCATC TTGCCGCCAT 
GATTGGCACC AGACAGATTC CTTAGTAGTG GTGACTGTAT ATGGCCAGAT TCCACTTCCT 
GCGTTTAACT GGGTGAAGGC CAGTCAAACT GAGCTTCATG TCCACATTGT CTTTGATGGT 
AACCGTGTGT TCCAAGCACA GATGAAGCTC TGGGGGGTCA TAAACGTGGA GCAGAGCTCT 
GTCTTCTTGA TGCCATCTCG GGTTGAAATC TCCCTGGTCA AGGCTGACCC AGGATCCTGG 
GCCCAGCTGG AGCACCCTGA TGCACTAGCT AAGAAGGCTA GGGCAGGGGT TGTGTTAGAG 
ATGGATGAGG AAGAATCTGA CGATTCAGAT GATGATCTGA GCTGGACAGA GGAGGAGGAA 
GAGGAGGAAG CAATGGGGGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGB1BP2 ( NM_012278.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036410.1 Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.

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CloneID	OHu66964
Clone ID Related Accession (Same CDS sequence)	NM_012278.3 , NM_012278.2 , NM_012278.4
Accession Version	NM_012278.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	integrin beta-1-binding protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA895605.1 and AF110225.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_012278.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.133193.1, SRR5189655.208466.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373829.8/ ENSP00000362935.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTCTAC TCTGTCGTAA CAAAGGCTGT GGGCAGCACT TTGACCCTAA TACCAACCTT 
CCTGATTCCT GTTGCCATCA CCCTGGGGTC CCAATCTTCC ATGATGCACT TAAGGGTTGG 
TCCTGCTGCC GAAAGCGAAC TGTAGATTTC TCTGAGTTCT TAAACATCAA GGGCTGTACT 
ATGGGACCAC ACTGTGCTGA GAAGCTTCCT GAGGCCCCTC AACCTGAAGG CCCTGCTACA 
AGCAGTTCAC TTCAGGAGCA AAAACCTCTG AATGTGATTC CAAAGTCAGC AGAGACCTTG 
CGCCGGGAGA GGCCCAAGTC AGAGTTGCCT CTGAAGCTGC TGCCGCTAAA TATATCCCAA 
GCCCTGGAAA TGGCATTGGA ACAGAAGGAA TTAGACCAGG AACCTGGGGC AGGACTTGAC 
AGTCTGATCC GGACTGGTTC CAGCTGCCAG AACCCAGGAT GTGATGCTGT TTACCAAGGC 
CCTGAGAGTG ATGCTACTCC ATGTACCTAC CACCCAGGAG CACCCCGATT CCATGAGGGG 
ATGAAGTCTT GGAGCTGTTG TGGCATCCAG ACCCTGGATT TTGGGGCATT CTTGGCACAA 
CCAGGGTGCA GAGTCGGTAG ACATGACTGG GGGAAGCAGC TCCCAGCATC TTGCCGCCAT 
GATTGGCACC AGACAGATTC CTTAGTAGTG GTGACTGTAT ATGGCCAGAT TCCACTTCCT 
GCGTTTAACT GGGTGAAGGC CAGTCAAACT GAGCTTCATG TCCACATTGT CTTTGATGGT 
AACCGTGTGT TCCAAGCACA GATGAAGCTC TGGGGGGTCA TAAACGTGGA GCAGAGCTCT 
GTCTTCTTGA TGCCATCTCG GGTTGAAATC TCCCTGGTCA AGGCTGACCC AGGATCCTGG 
GCCCAGCTGG AGCACCCTGA TGCACTAGCT AAGAAGGCTA GGGCAGGGGT TGTGTTAGAG 
ATGGATGAGG AAGAATCTGA CGATTCAGAT GATGATCTGA GCTGGACAGA GGAGGAGGAA 
GAGGAGGAAG CAATGGGGGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036410.1
CDS	58..1101
Translation	MSLLCRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTMGPHCAEKLPEAPQPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQALEMALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE

Target ORF information:

RefSeq Version	NM_012278.4
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012278.4

ORF Insert Sequence:

ATGTCTCTAC TCTGTCGTAA CAAAGGCTGT GGGCAGCACT TTGACCCTAA TACCAACCTT 
CCTGATTCCT GTTGCCATCA CCCTGGGGTC CCAATCTTCC ATGATGCACT TAAGGGTTGG 
TCCTGCTGCC GAAAGCGAAC TGTAGATTTC TCTGAGTTCT TAAACATCAA GGGCTGTACT 
ATGGGACCAC ACTGTGCTGA GAAGCTTCCT GAGGCCCCTC AACCTGAAGG CCCTGCTACA 
AGCAGTTCAC TTCAGGAGCA AAAACCTCTG AATGTGATTC CAAAGTCAGC AGAGACCTTG 
CGCCGGGAGA GGCCCAAGTC AGAGTTGCCT CTGAAGCTGC TGCCGCTAAA TATATCCCAA 
GCCCTGGAAA TGGCATTGGA ACAGAAGGAA TTAGACCAGG AACCTGGGGC AGGACTTGAC 
AGTCTGATCC GGACTGGTTC CAGCTGCCAG AACCCAGGAT GTGATGCTGT TTACCAAGGC 
CCTGAGAGTG ATGCTACTCC ATGTACCTAC CACCCAGGAG CACCCCGATT CCATGAGGGG 
ATGAAGTCTT GGAGCTGTTG TGGCATCCAG ACCCTGGATT TTGGGGCATT CTTGGCACAA 
CCAGGGTGCA GAGTCGGTAG ACATGACTGG GGGAAGCAGC TCCCAGCATC TTGCCGCCAT 
GATTGGCACC AGACAGATTC CTTAGTAGTG GTGACTGTAT ATGGCCAGAT TCCACTTCCT 
GCGTTTAACT GGGTGAAGGC CAGTCAAACT GAGCTTCATG TCCACATTGT CTTTGATGGT 
AACCGTGTGT TCCAAGCACA GATGAAGCTC TGGGGGGTCA TAAACGTGGA GCAGAGCTCT 
GTCTTCTTGA TGCCATCTCG GGTTGAAATC TCCCTGGTCA AGGCTGACCC AGGATCCTGG 
GCCCAGCTGG AGCACCCTGA TGCACTAGCT AAGAAGGCTA GGGCAGGGGT TGTGTTAGAG 
ATGGATGAGG AAGAATCTGA CGATTCAGAT GATGATCTGA GCTGGACAGA GGAGGAGGAA 
GAGGAGGAAG CAATGGGGGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGB1BP2 ( XM_017029405.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016884894.1 Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu99237
Clone ID Related Accession (Same CDS sequence)	XM_017029405.1
Accession Version	XM_017029405.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	integrin beta-1-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCACT TAAGGTCAGA GTTGCCTCTG AAGCTGCTGC CGCTAAATAT ATCCCAAGCC 
CTGGAAATGG CATTGGAACA GAAGGAATTA GACCAGGAAC CTGGGGCAGG ACTTGACAGT 
CTGATCCGGA CTGGTTCCAG CTGCCAGAAC CCAGGATGTG ATGCTGTTTA CCAAGGCCCT 
GAGAGTGATG CTACTCCATG TACCTACCAC CCAGGAGCAC CCCGATTCCA TGAGGGGATG 
AAGTCTTGGA GCTGTTGTGG CATCCAGACC CTGGATTTTG GGGCATTCTT GGCACAACCA 
GGGTGCAGAG TCGGTAGACA TGACTGGGGG AAGCAGCTCC CAGCATCTTG CCGCCATGAT 
TGGCACCAGA CAGATTCCTT AGTAGTGGTG ACTGTATATG GCCAGATTCC ACTTCCTGCG 
TTTAACTGGG TGAAGGCCAG TCAAACTGAG CTTCATGTCC ACATTGTCTT TGATGGTAAC 
CGTGTGTTCC AAGCACAGAT GAAGCTCTGG GGGGTCATAA ACGTGGAGCA GAGCTCTGTC 
TTCTTGATGC CATCTCGGGT TGAAATCTCC CTGGTCAAGG CTGACCCAGG ATCCTGGGCC 
CAGCTGGAGC ACCCTGATGC ACTAGCTAAG AAGGCTAGGG CAGGGGTTGT GTTAGAGATG 
GATGAGGAAG AATCTGACGA TTCAGATGAT GATCTGAGCT GGACAGAGGA GGAGGAAGAG 
GAGGAAGCAA TGGGGGAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016884894.1
CDS	633..1373
Translation	MMHLRSELPLKLLPLNISQALEMALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE

Target ORF information:

RefSeq Version	XM_017029405.1
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit beta 1 binding protein 2 (ITGB1BP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029405.1

ORF Insert Sequence:

ATGATGCACT TAAGGTCAGA GTTGCCTCTG AAGCTGCTGC CGCTAAATAT ATCCCAAGCC 
CTGGAAATGG CATTGGAACA GAAGGAATTA GACCAGGAAC CTGGGGCAGG ACTTGACAGT 
CTGATCCGGA CTGGTTCCAG CTGCCAGAAC CCAGGATGTG ATGCTGTTTA CCAAGGCCCT 
GAGAGTGATG CTACTCCATG TACCTACCAC CCAGGAGCAC CCCGATTCCA TGAGGGGATG 
AAGTCTTGGA GCTGTTGTGG CATCCAGACC CTGGATTTTG GGGCATTCTT GGCACAACCA 
GGGTGCAGAG TCGGTAGACA TGACTGGGGG AAGCAGCTCC CAGCATCTTG CCGCCATGAT 
TGGCACCAGA CAGATTCCTT AGTAGTGGTG ACTGTATATG GCCAGATTCC ACTTCCTGCG 
TTTAACTGGG TGAAGGCCAG TCAAACTGAG CTTCATGTCC ACATTGTCTT TGATGGTAAC 
CGTGTGTTCC AAGCACAGAT GAAGCTCTGG GGGGTCATAA ACGTGGAGCA GAGCTCTGTC 
TTCTTGATGC CATCTCGGGT TGAAATCTCC CTGGTCAAGG CTGACCCAGG ATCCTGGGCC 
CAGCTGGAGC ACCCTGATGC ACTAGCTAAG AAGGCTAGGG CAGGGGTTGT GTTAGAGATG 
GATGAGGAAG AATCTGACGA TTCAGATGAT GATCTGAGCT GGACAGAGGA GGAGGAAGAG 
GAGGAAGCAA TGGGGGAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Cell158(2)434-448(2014 Jul)
Taipale M,Tucker G,Peng J,Krykbaeva I,Lin ZY,Larsen B,Choi H,Berger B,Gingras AC,Lindquist S

Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy.
Gene512(2)206-10(2013 Jan)
Ruppert V,Meyer T,Richter A,Maisch B,Pankuweit S,

Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1.
The Journal of biological chemistry288(1)215-22(2013 Jan)
Hong TJ,Kim S,Wi AR,Lee P,Kang M,Jeong JH,Hahn JS

Morgana and melusin: two fairies chaperoning signal transduction.
Cell cycle (Georgetown, Tex.)10(21)3678-83(2011 Nov)
Ferretti R,Sbroggi? M,Di Savino A,Fusella F,Bertero A,Michowski W,Tarone G,Brancaccio M

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ITGB1BP2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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