GAS6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GAS6
Entrez Gene ID	2621
Full Name	growth arrest specific 6
Synonyms	AXLLG,AXSF
General protein information	Preferred Names growth arrest specific 6 Names growth arrest-specific protein 6 AXL receptor tyrosine kinase ligand AXL stimulatory factor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q34
Summary	This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014].
Disorder MIM:	600441

mRNA and Protein(s)

mRNA	Protein	Name
NM_000820.3	NP_000811.1	growth arrest-specific protein 6 precursor
NM_000820.4	NP_000811.1	growth arrest-specific protein 6 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GAS6	XP_001146448.2
Canis lupus familiaris (dog)	GAS6	XP_849623.2
Gallus gallus (chicken)	GAS6	XP_416936.4
Danio rerio (zebrafish)	gas6	NP_956272.1
Xenopus tropicalis (tropical clawed frog)	gas6	NP_001015965.1
	GAS6	XP_002800893.1
Bos taurus (cattle)	GAS6	XP_005214103.1
Rattus norvegicus (Norway rat)	Gas6	NP_476441.2
Homo sapiens (human)	GAS6	NP_000811.1
Mus musculus (house mouse)	Gas6	NP_062394.2

Gene Ontology
Bibliography

Related articles in PubMed

Expression and role of TYRO3 and AXL as potential therapeutical targets in leiomyosarcoma.
Dantas-Barbosa C, Lesluyes T, Loarer FL, Chibon F, Treilleux I, Coindre JM, Meeus P, Brahmi M, Bally O, Ray-Coquard I, Sunyach MP, Cesne AL, Mir O, Bonvalot S, Toulmonde M, Italiano A, Saintigny P, Jean-Denis M, Ducimetiere F, Ranchere D, El Sayadi H, Alberti L, Blay JY
British journal of cancer117(12)1787-1797(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results show that TYRO3, AXL and GAS6 are expressed at higher levels in LMS and expression of its ligands correlates to a worse PFS in LMS patients.
Title: Expression and role of TYRO3 and AXL as potential therapeutical targets in leiomyosarcoma.

The expression of AXL was positively associated with GAS6 expression (P < 0.001), and tumor differentiation (P = 0.014) in advanced NSCLC with metastases. AXL expression displayed no association with gender, age, smoking history, pathology, T stage, N stage, CEA, and LDH.
Title: AXL-GAS6 expression can predict for adverse prognosis in non-small cell lung cancer with brain metastases.

Our data suggest that a TT genotype at +1332C/T polymorphism might be associated with decreased risk for preeclampsia, but the 834+7G/A polymorphism is not associated with the disorder, in the Chinese population.
Title: Association study between GAS6 gene polymorphisms and risk of preeclampsia in Chinese population.

Data show that the variant growth arrest specific 6 (GAS6) +1332 T allele is associated with a decreased risk for severe preeclampsia in a South West Han Chinese population, but the 834+7G/A polymorphism has no effect on the severe preeclampsia.
Title: [Association study between 834+7G/A and +1332C/T polymorphisms in the growth arrest specific 6 gene and risk of severe preeclampsia in Chinese population].

In conclusion, our study shows that SNPsrs8191974 and rs2028299 of the Gas6 are significantly associated with type 2 diabetes mellitus (T2DM) in the Chinese population
Title: The Gas6 gene rs8191974 and Ap3s2 gene rs2028299 are associated with type 2 diabetes in the northern Chinese Han population.

The following GAS6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GAS6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19630	NM_000820.4 Latest version!	Homo sapiens growth arrest specific 6 (GAS6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu19630	NM_000820.3	Homo sapiens growth arrest specific 6 (GAS6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GAS6 ( NM_000820.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000811.1 Homo sapiens growth arrest specific 6 (GAS6), mRNA.

Price & Availability↑

CloneID	OHu19630
Clone ID Related Accession (Same CDS sequence)	NM_000820.3 , NM_000820.4
Accession Version	NM_000820.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	growth arrest-specific protein 6 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX380508.2, HY038614.1, BC038984.1 and AA045119.1. This sequence is a reference standard in the RefSeqGene project. On Aug 18, 2014 this sequence version replaced NM_000820.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279841.6559.1, BC038984.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCCTT CGCTCTCGCC CGGGCCCGCC GCCCTGCGCC GCGCGCCGCA GCTGCTGCTG 
CTGCTGCTGG CCGCGGAGTG CGCGCTTGCC GCGCTGTTGC CGGCGCGCGA GGCCACGCAG 
TTCCTGCGGC CCAGGCAGCG CCGCGCCTTT CAGGTCTTCG AGGAGGCCAA GCAGGGCCAC 
CTGGAGAGGG AGTGCGTGGA GGAGCTGTGC AGCCGCGAGG AGGCGCGGGA GGTGTTCGAG 
AACGACCCCG AGACGGATTA TTTTTACCCA AGATACTTAG ACTGCATCAA CAAGTATGGG 
TCTCCGTACA CCAAAAACTC AGGCTTCGCC ACCTGCGTGC AAAACCTGCC TGACCAGTGC 
ACGCCCAACC CCTGCGATAG GAAGGGGACC CAAGCCTGCC AGGACCTCAT GGGCAACTTC 
TTCTGCCTGT GTAAAGCTGG CTGGGGGGGC CGGCTCTGCG ACAAAGATGT CAACGAATGC 
AGCCAGGAGA ACGGGGGCTG CCTCCAGATC TGCCACAACA AGCCGGGTAG CTTCCACTGT 
TCCTGCCACA GCGGCTTCGA GCTCTCCTCT GATGGCAGGA CCTGCCAAGA CATAGACGAG 
TGCGCAGACT CGGAGGCCTG CGGGGAGGCG CGCTGCAAGA ACCTGCCCGG CTCCTACTCC 
TGCCTCTGTG ACGAGGGCTT TGCGTACAGC TCCCAGGAGA AGGCTTGCCG AGATGTGGAC 
GAGTGTCTGC AGGGCCGCTG TGAGCAGGTC TGCGTGAACT CCCCAGGGAG CTACACCTGC 
CACTGTGACG GGCGTGGGGG CCTCAAGCTG TCCCAGGACA TGGACACCTG TGAGGACATC 
TTGCCGTGCG TGCCCTTCAG CGTGGCCAAG AGTGTGAAGT CCTTGTACCT GGGCCGGATG 
TTCAGTGGGA CCCCCGTGAT CCGACTGCGC TTCAAGAGGC TGCAGCCCAC CAGGCTGGTA 
GCTGAGTTTG ACTTCCGGAC CTTTGACCCC GAGGGCATCC TCCTCTTTGC CGGAGGCCAC 
CAGGACAGCA CCTGGATCGT GCTGGCCCTG AGAGCCGGCC GGCTGGAGCT GCAGCTGCGC 
TACAACGGTG TCGGCCGTGT CACCAGCAGC GGCCCGGTCA TCAACCATGG CATGTGGCAG 
ACAATCTCTG TTGAGGAGCT GGCGCGGAAT CTGGTCATCA AGGTCAACAG GGATGCTGTC 
ATGAAAATCG CGGTGGCCGG GGACTTGTTC CAACCGGAGC GAGGACTGTA TCATCTGAAC 
CTGACCGTGG GAGGTATTCC CTTCCATGAG AAGGACCTCG TGCAGCCTAT AAACCCTCGT 
CTGGATGGCT GCATGAGGAG CTGGAACTGG CTGAACGGAG AAGACACCAC CATCCAGGAA 
ACGGTGAAAG TGAACACGAG GATGCAGTGC TTCTCGGTGA CGGAGAGAGG CTCTTTCTAC 
CCCGGGAGCG GCTTCGCCTT CTACAGCCTG GACTACATGC GGACCCCTCT GGACGTCGGG 
ACTGAATCAA CCTGGGAAGT AGAAGTCGTG GCTCACATCC GCCCAGCCGC AGACACAGGC 
GTGCTGTTTG CGCTCTGGGC CCCCGACCTC CGTGCCGTGC CTCTCTCTGT GGCACTGGTA 
GACTATCACT CCACGAAGAA ACTCAAGAAG CAGCTGGTGG TCCTGGCCGT GGAGCATACG 
GCCTTGGCCC TAATGGAGAT CAAGGTCTGC GACGGCCAAG AGCACGTGGT CACCGTCTCG 
CTGAGGGACG GTGAGGCCAC CCTGGAGGTG GACGGCACCA GGGGCCAGAG CGAGGTGAGC 
GCCGCGCAGC TGCAGGAGAG GCTGGCCGTG CTCGAGAGGC ACCTGCGGAG CCCCGTGCTC 
ACCTTTGCTG GCGGCCTGCC AGATGTGCCG GTGACTTCAG CGCCAGTCAC CGCGTTCTAC 
CGCGGCTGCA TGACACTGGA GGTCAACCGG AGGCTGCTGG ACCTGGACGA GGCGGCGTAC 
AAGCACAGCG ACATCACGGC CCACTCCTGC CCCCCCGTGG AGCCCGCCGC AGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000811.1
CDS	184..2220
Translation	MAPSLSPGPAALRRAPQLLLLLLAAECALAALLPAREATQFLRPRQRRAFQVFEEAKQGHLERECVEELCSREEAREVFENDPETDYFYPRYLDCINKYGSPYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPTRLVAEFDFRTFDPEGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHGMWQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPFHEKDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSFYPGSGFAFYSLDYMRTPLDVGTESTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVALVDYHSTKKLKKQLVVLAVEHTALALMEIKVCDGQEHVVTVSLRDGEATLEVDGTRGQSEVSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTLEVNRRLLDLDEAAYKHSDITAHSCPPVEPAAA

Target ORF information:

RefSeq Version	NM_000820.3
Organism	Homo sapiens(human)
Definition	Homo sapiens growth arrest specific 6 (GAS6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000820.3

ORF Insert Sequence:

ATGGCCCCTT CGCTCTCGCC CGGGCCCGCC GCCCTGCGCC GCGCGCCGCA GCTGCTGCTG 
CTGCTGCTGG CCGCGGAGTG CGCGCTTGCC GCGCTGTTGC CGGCGCGCGA GGCCACGCAG 
TTCCTGCGGC CCAGGCAGCG CCGCGCCTTT CAGGTCTTCG AGGAGGCCAA GCAGGGCCAC 
CTGGAGAGGG AGTGCGTGGA GGAGCTGTGC AGCCGCGAGG AGGCGCGGGA GGTGTTCGAG 
AACGACCCCG AGACGGATTA TTTTTACCCA AGATACTTAG ACTGCATCAA CAAGTATGGG 
TCTCCGTACA CCAAAAACTC AGGCTTCGCC ACCTGCGTGC AAAACCTGCC TGACCAGTGC 
ACGCCCAACC CCTGCGATAG GAAGGGGACC CAAGCCTGCC AGGACCTCAT GGGCAACTTC 
TTCTGCCTGT GTAAAGCTGG CTGGGGGGGC CGGCTCTGCG ACAAAGATGT CAACGAATGC 
AGCCAGGAGA ACGGGGGCTG CCTCCAGATC TGCCACAACA AGCCGGGTAG CTTCCACTGT 
TCCTGCCACA GCGGCTTCGA GCTCTCCTCT GATGGCAGGA CCTGCCAAGA CATAGACGAG 
TGCGCAGACT CGGAGGCCTG CGGGGAGGCG CGCTGCAAGA ACCTGCCCGG CTCCTACTCC 
TGCCTCTGTG ACGAGGGCTT TGCGTACAGC TCCCAGGAGA AGGCTTGCCG AGATGTGGAC 
GAGTGTCTGC AGGGCCGCTG TGAGCAGGTC TGCGTGAACT CCCCAGGGAG CTACACCTGC 
CACTGTGACG GGCGTGGGGG CCTCAAGCTG TCCCAGGACA TGGACACCTG TGAGGACATC 
TTGCCGTGCG TGCCCTTCAG CGTGGCCAAG AGTGTGAAGT CCTTGTACCT GGGCCGGATG 
TTCAGTGGGA CCCCCGTGAT CCGACTGCGC TTCAAGAGGC TGCAGCCCAC CAGGCTGGTA 
GCTGAGTTTG ACTTCCGGAC CTTTGACCCC GAGGGCATCC TCCTCTTTGC CGGAGGCCAC 
CAGGACAGCA CCTGGATCGT GCTGGCCCTG AGAGCCGGCC GGCTGGAGCT GCAGCTGCGC 
TACAACGGTG TCGGCCGTGT CACCAGCAGC GGCCCGGTCA TCAACCATGG CATGTGGCAG 
ACAATCTCTG TTGAGGAGCT GGCGCGGAAT CTGGTCATCA AGGTCAACAG GGATGCTGTC 
ATGAAAATCG CGGTGGCCGG GGACTTGTTC CAACCGGAGC GAGGACTGTA TCATCTGAAC 
CTGACCGTGG GAGGTATTCC CTTCCATGAG AAGGACCTCG TGCAGCCTAT AAACCCTCGT 
CTGGATGGCT GCATGAGGAG CTGGAACTGG CTGAACGGAG AAGACACCAC CATCCAGGAA 
ACGGTGAAAG TGAACACGAG GATGCAGTGC TTCTCGGTGA CGGAGAGAGG CTCTTTCTAC 
CCCGGGAGCG GCTTCGCCTT CTACAGCCTG GACTACATGC GGACCCCTCT GGACGTCGGG 
ACTGAATCAA CCTGGGAAGT AGAAGTCGTG GCTCACATCC GCCCAGCCGC AGACACAGGC 
GTGCTGTTTG CGCTCTGGGC CCCCGACCTC CGTGCCGTGC CTCTCTCTGT GGCACTGGTA 
GACTATCACT CCACGAAGAA ACTCAAGAAG CAGCTGGTGG TCCTGGCCGT GGAGCATACG 
GCCTTGGCCC TAATGGAGAT CAAGGTCTGC GACGGCCAAG AGCACGTGGT CACCGTCTCG 
CTGAGGGACG GTGAGGCCAC CCTGGAGGTG GACGGCACCA GGGGCCAGAG CGAGGTGAGC 
GCCGCGCAGC TGCAGGAGAG GCTGGCCGTG CTCGAGAGGC ACCTGCGGAG CCCCGTGCTC 
ACCTTTGCTG GCGGCCTGCC AGATGTGCCG GTGACTTCAG CGCCAGTCAC CGCGTTCTAC 
CGCGGCTGCA TGACACTGGA GGTCAACCGG AGGCTGCTGG ACCTGGACGA GGCGGCGTAC 
AAGCACAGCG ACATCACGGC CCACTCCTGC CCCCCCGTGG AGCCCGCCGC AGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GAS6 ( NM_000820.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000811.1 Homo sapiens growth arrest specific 6 (GAS6), mRNA.

Price & Availability↑

CloneID	OHu19630
Clone ID Related Accession (Same CDS sequence)	NM_000820.3 , NM_000820.4
Accession Version	NM_000820.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	growth arrest-specific protein 6 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY038614.1, BC038984.1 and AA045119.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000820.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279841.6559.1, BC030708.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000327773.7/ ENSP00000331831.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCCCTT CGCTCTCGCC CGGGCCCGCC GCCCTGCGCC GCGCGCCGCA GCTGCTGCTG 
CTGCTGCTGG CCGCGGAGTG CGCGCTTGCC GCGCTGTTGC CGGCGCGCGA GGCCACGCAG 
TTCCTGCGGC CCAGGCAGCG CCGCGCCTTT CAGGTCTTCG AGGAGGCCAA GCAGGGCCAC 
CTGGAGAGGG AGTGCGTGGA GGAGCTGTGC AGCCGCGAGG AGGCGCGGGA GGTGTTCGAG 
AACGACCCCG AGACGGATTA TTTTTACCCA AGATACTTAG ACTGCATCAA CAAGTATGGG 
TCTCCGTACA CCAAAAACTC AGGCTTCGCC ACCTGCGTGC AAAACCTGCC TGACCAGTGC 
ACGCCCAACC CCTGCGATAG GAAGGGGACC CAAGCCTGCC AGGACCTCAT GGGCAACTTC 
TTCTGCCTGT GTAAAGCTGG CTGGGGGGGC CGGCTCTGCG ACAAAGATGT CAACGAATGC 
AGCCAGGAGA ACGGGGGCTG CCTCCAGATC TGCCACAACA AGCCGGGTAG CTTCCACTGT 
TCCTGCCACA GCGGCTTCGA GCTCTCCTCT GATGGCAGGA CCTGCCAAGA CATAGACGAG 
TGCGCAGACT CGGAGGCCTG CGGGGAGGCG CGCTGCAAGA ACCTGCCCGG CTCCTACTCC 
TGCCTCTGTG ACGAGGGCTT TGCGTACAGC TCCCAGGAGA AGGCTTGCCG AGATGTGGAC 
GAGTGTCTGC AGGGCCGCTG TGAGCAGGTC TGCGTGAACT CCCCAGGGAG CTACACCTGC 
CACTGTGACG GGCGTGGGGG CCTCAAGCTG TCCCAGGACA TGGACACCTG TGAGGACATC 
TTGCCGTGCG TGCCCTTCAG CGTGGCCAAG AGTGTGAAGT CCTTGTACCT GGGCCGGATG 
TTCAGTGGGA CCCCCGTGAT CCGACTGCGC TTCAAGAGGC TGCAGCCCAC CAGGCTGGTA 
GCTGAGTTTG ACTTCCGGAC CTTTGACCCC GAGGGCATCC TCCTCTTTGC CGGAGGCCAC 
CAGGACAGCA CCTGGATCGT GCTGGCCCTG AGAGCCGGCC GGCTGGAGCT GCAGCTGCGC 
TACAACGGTG TCGGCCGTGT CACCAGCAGC GGCCCGGTCA TCAACCATGG CATGTGGCAG 
ACAATCTCTG TTGAGGAGCT GGCGCGGAAT CTGGTCATCA AGGTCAACAG GGATGCTGTC 
ATGAAAATCG CGGTGGCCGG GGACTTGTTC CAACCGGAGC GAGGACTGTA TCATCTGAAC 
CTGACCGTGG GAGGTATTCC CTTCCATGAG AAGGACCTCG TGCAGCCTAT AAACCCTCGT 
CTGGATGGCT GCATGAGGAG CTGGAACTGG CTGAACGGAG AAGACACCAC CATCCAGGAA 
ACGGTGAAAG TGAACACGAG GATGCAGTGC TTCTCGGTGA CGGAGAGAGG CTCTTTCTAC 
CCCGGGAGCG GCTTCGCCTT CTACAGCCTG GACTACATGC GGACCCCTCT GGACGTCGGG 
ACTGAATCAA CCTGGGAAGT AGAAGTCGTG GCTCACATCC GCCCAGCCGC AGACACAGGC 
GTGCTGTTTG CGCTCTGGGC CCCCGACCTC CGTGCCGTGC CTCTCTCTGT GGCACTGGTA 
GACTATCACT CCACGAAGAA ACTCAAGAAG CAGCTGGTGG TCCTGGCCGT GGAGCATACG 
GCCTTGGCCC TAATGGAGAT CAAGGTCTGC GACGGCCAAG AGCACGTGGT CACCGTCTCG 
CTGAGGGACG GTGAGGCCAC CCTGGAGGTG GACGGCACCA GGGGCCAGAG CGAGGTGAGC 
GCCGCGCAGC TGCAGGAGAG GCTGGCCGTG CTCGAGAGGC ACCTGCGGAG CCCCGTGCTC 
ACCTTTGCTG GCGGCCTGCC AGATGTGCCG GTGACTTCAG CGCCAGTCAC CGCGTTCTAC 
CGCGGCTGCA TGACACTGGA GGTCAACCGG AGGCTGCTGG ACCTGGACGA GGCGGCGTAC 
AAGCACAGCG ACATCACGGC CCACTCCTGC CCCCCCGTGG AGCCCGCCGC AGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000811.1
CDS	157..2193
Translation	MAPSLSPGPAALRRAPQLLLLLLAAECALAALLPAREATQFLRPRQRRAFQVFEEAKQGHLERECVEELCSREEAREVFENDPETDYFYPRYLDCINKYGSPYTKNSGFATCVQNLPDQCTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPTRLVAEFDFRTFDPEGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHGMWQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPFHEKDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSFYPGSGFAFYSLDYMRTPLDVGTESTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVALVDYHSTKKLKKQLVVLAVEHTALALMEIKVCDGQEHVVTVSLRDGEATLEVDGTRGQSEVSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTLEVNRRLLDLDEAAYKHSDITAHSCPPVEPAAA

Target ORF information:

RefSeq Version	NM_000820.4
Organism	Homo sapiens(human)
Definition	Homo sapiens growth arrest specific 6 (GAS6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000820.4

ORF Insert Sequence:

ATGGCCCCTT CGCTCTCGCC CGGGCCCGCC GCCCTGCGCC GCGCGCCGCA GCTGCTGCTG 
CTGCTGCTGG CCGCGGAGTG CGCGCTTGCC GCGCTGTTGC CGGCGCGCGA GGCCACGCAG 
TTCCTGCGGC CCAGGCAGCG CCGCGCCTTT CAGGTCTTCG AGGAGGCCAA GCAGGGCCAC 
CTGGAGAGGG AGTGCGTGGA GGAGCTGTGC AGCCGCGAGG AGGCGCGGGA GGTGTTCGAG 
AACGACCCCG AGACGGATTA TTTTTACCCA AGATACTTAG ACTGCATCAA CAAGTATGGG 
TCTCCGTACA CCAAAAACTC AGGCTTCGCC ACCTGCGTGC AAAACCTGCC TGACCAGTGC 
ACGCCCAACC CCTGCGATAG GAAGGGGACC CAAGCCTGCC AGGACCTCAT GGGCAACTTC 
TTCTGCCTGT GTAAAGCTGG CTGGGGGGGC CGGCTCTGCG ACAAAGATGT CAACGAATGC 
AGCCAGGAGA ACGGGGGCTG CCTCCAGATC TGCCACAACA AGCCGGGTAG CTTCCACTGT 
TCCTGCCACA GCGGCTTCGA GCTCTCCTCT GATGGCAGGA CCTGCCAAGA CATAGACGAG 
TGCGCAGACT CGGAGGCCTG CGGGGAGGCG CGCTGCAAGA ACCTGCCCGG CTCCTACTCC 
TGCCTCTGTG ACGAGGGCTT TGCGTACAGC TCCCAGGAGA AGGCTTGCCG AGATGTGGAC 
GAGTGTCTGC AGGGCCGCTG TGAGCAGGTC TGCGTGAACT CCCCAGGGAG CTACACCTGC 
CACTGTGACG GGCGTGGGGG CCTCAAGCTG TCCCAGGACA TGGACACCTG TGAGGACATC 
TTGCCGTGCG TGCCCTTCAG CGTGGCCAAG AGTGTGAAGT CCTTGTACCT GGGCCGGATG 
TTCAGTGGGA CCCCCGTGAT CCGACTGCGC TTCAAGAGGC TGCAGCCCAC CAGGCTGGTA 
GCTGAGTTTG ACTTCCGGAC CTTTGACCCC GAGGGCATCC TCCTCTTTGC CGGAGGCCAC 
CAGGACAGCA CCTGGATCGT GCTGGCCCTG AGAGCCGGCC GGCTGGAGCT GCAGCTGCGC 
TACAACGGTG TCGGCCGTGT CACCAGCAGC GGCCCGGTCA TCAACCATGG CATGTGGCAG 
ACAATCTCTG TTGAGGAGCT GGCGCGGAAT CTGGTCATCA AGGTCAACAG GGATGCTGTC 
ATGAAAATCG CGGTGGCCGG GGACTTGTTC CAACCGGAGC GAGGACTGTA TCATCTGAAC 
CTGACCGTGG GAGGTATTCC CTTCCATGAG AAGGACCTCG TGCAGCCTAT AAACCCTCGT 
CTGGATGGCT GCATGAGGAG CTGGAACTGG CTGAACGGAG AAGACACCAC CATCCAGGAA 
ACGGTGAAAG TGAACACGAG GATGCAGTGC TTCTCGGTGA CGGAGAGAGG CTCTTTCTAC 
CCCGGGAGCG GCTTCGCCTT CTACAGCCTG GACTACATGC GGACCCCTCT GGACGTCGGG 
ACTGAATCAA CCTGGGAAGT AGAAGTCGTG GCTCACATCC GCCCAGCCGC AGACACAGGC 
GTGCTGTTTG CGCTCTGGGC CCCCGACCTC CGTGCCGTGC CTCTCTCTGT GGCACTGGTA 
GACTATCACT CCACGAAGAA ACTCAAGAAG CAGCTGGTGG TCCTGGCCGT GGAGCATACG 
GCCTTGGCCC TAATGGAGAT CAAGGTCTGC GACGGCCAAG AGCACGTGGT CACCGTCTCG 
CTGAGGGACG GTGAGGCCAC CCTGGAGGTG GACGGCACCA GGGGCCAGAG CGAGGTGAGC 
GCCGCGCAGC TGCAGGAGAG GCTGGCCGTG CTCGAGAGGC ACCTGCGGAG CCCCGTGCTC 
ACCTTTGCTG GCGGCCTGCC AGATGTGCCG GTGACTTCAG CGCCAGTCAC CGCGTTCTAC 
CGCGGCTGCA TGACACTGGA GGTCAACCGG AGGCTGCTGG ACCTGGACGA GGCGGCGTAC 
AAGCACAGCG ACATCACGGC CCACTCCTGC CCCCCCGTGG AGCCCGCCGC AGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression and role of TYRO3 and AXL as potential therapeutical targets in leiomyosarcoma.
British journal of cancer117(12)1787-1797(2017 Dec)
Dantas-Barbosa C,Lesluyes T,Loarer FL,Chibon F,Treilleux I,Coindre JM,Meeus P,Brahmi M,Bally O,Ray-Coquard I,Sunyach MP,Cesne AL,Mir O,Bonvalot S,Toulmonde M,Italiano A,Saintigny P,Jean-Denis M,Ducimetiere F,Ranchere D,El Sayadi H,Alberti L,Blay JY

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GAS6 cDNA ORF clone, Homo sapiens(human)

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