SENP3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SENP3
Entrez Gene ID	26168
Full Name	SUMO1/sentrin/SMT3 specific peptidase 3
Synonyms	SMT3IP1,SSP3,Ulp1
General protein information	Preferred Names SUMO1/sentrin/SMT3 specific peptidase 3 Names sentrin-specific protease 3 SUMO-1-specific protease 3 sentrin/SUMO-specific protease 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.1
Summary	The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009].
Disorder MIM:	612844

mRNA and Protein(s)

mRNA	Protein	Name
NM_015670.5	NP_056485.2	sentrin-specific protease 3
NM_015670.6	NP_056485.2	sentrin-specific protease 3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SENP3	NP_001192057.1
	SENP3	XP_001110023.2
Homo sapiens (human)	SENP3	NP_056485.2
Bos taurus (cattle)	SENP3	NP_001178303.1
Mus musculus (house mouse)	Senp3	NP_109627.3
Rattus norvegicus (Norway rat)	Senp3	NP_001013134.2
Canis lupus familiaris (dog)	SENP3	XP_849635.1

Gene Ontology
Bibliography

Related articles in PubMed

Increased SUMO-2/3-ylation mediated by SENP3 degradation is protective against cadmium-induced caspase 3-dependent cytotoxicity.
Luo J, Gurung S, Lee L, Henley JM, Wilkinson KA, Guo C
The Journal of toxicological sciences42(5)529-538(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

our findings for the first time specifically supported that SUMO-specific protease 3 might play an important role in the regulation of epithelial ovarian cancer progression and could serve as a potential biomarker for prognosis as well as provide a promising therapeutic target against epithelial ovarian cancer
Title: Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.

SENP3 knockdown reduced cadmium-induced caspase 3 cleavage and cell death in PC12 cells, while SENP3 overexpression enhanced cell death.
Title: Increased SUMO-2/3-ylation mediated by SENP3 degradation is protective against cadmium-induced caspase 3-dependent cytotoxicity.

Our data identified SUMOylation as a previously undescribed post-translational modification of STAT3 and SENP3 as a critical positive modulator of tobacco- or cytokine-induced STAT3 activation.
Title: SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer.

The data demonstrate that SUMO2 conjugation and SENP3-driven deSUMOylation of PELP1 is instrumental for ordered progression of ribosome maturation, and they provide molecular insight into the dynamics of ribosome maturation.
Title: The AAA ATPase MDN1 Acts as a SUMO-Targeted Regulator in Mammalian Pre-ribosome Remodeling.

In early-onset pre-eclampsia, enhanced deSUMOylation of HIF1A by SENP3 may in part contribute to increased HIF1A activity and stability found in this pathology.
Title: Dynamic regulation of HIF1? stability by SUMO2/3 and SENP3 in the human placenta.

The following SENP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SENP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09639	NM_015670.6 Latest version!	Homo sapiens SUMO specific peptidase 3 (SENP3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
View Old Accession Versions >>
OHu09639	NM_015670.5	Homo sapiens SUMO1/sentrin/SMT3 specific peptidase 3 (SENP3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SENP3 ( NM_015670.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056485.2 Homo sapiens SUMO1/sentrin/SMT3 specific peptidase 3 (SENP3), mRNA.

Price & Availability↑

CloneID	OHu09639
Clone ID Related Accession (Same CDS sequence)	NM_015670.5 , NM_015670.6
Accession Version	NM_015670.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-08
Organism	Homo sapiens(human)
Product	sentrin-specific protease 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ956948.1, BQ424754.1, CX165088.1, BC048306.1 and BF514106.1. On Mar 4, 2011 this sequence version replaced NM_015670.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.418579.1, SRR1163655.396429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGAGA CTATACAAGG GACCGGGTCC TGGGGGCCTG AGCCTCCTGG ACCCGGCATA 
CCCCCAGCTT ACTCAAGTCC CAGGCGGGAG CGTCTTCGTT GGCCCCCACC TCCCAAACCC 
CGACTCAAGT CAGGTGGAGG GTTTGGGCCA GATCCTGGGT CAGGGACCAC AGTGCCAGCC 
AGACGCCTCC CTGTCCCCCG ACCCTCTTTT GATGCCTCAG CAAGTGAAGA GGAGGAAGAA 
GAGGAGGAGG AGGAGGATGA AGATGAAGAG GAGGAAGTGG CAGCTTGGAG GCTGCCCCCA 
AGATGGAGTC AGCTGGGAAC CTCCCAGCGG CCCCGCCCTT CCCGCCCCAC TCATCGAAAA 
ACCTGCTCAC AGCGCCGCCG CCGAGCCATG AGAGCCTTCC GGATGCTGCT CTACTCAAAA 
AGCACCTCGC TGACATTCCA CTGGAAGCTT TGGGGGCGCC ACCGGGGCCG GCGGCGGGGC 
CTCGCACACC CCAAGAACCA TCTTTCACCC CAGCAAGGGG GTGCGACGCC ACAGGTGCCA 
TCCCCCTGTT GTCGTTTTGA CTCCCCCCGG GGGCCACCTC CACCCCGGCT GGGTCTGCTA 
GGTGCTCTCA TGGCTGAGGA TGGGGTGAGA GGGTCTCCAC CAGTGCCCTC TGGGCCCCCC 
ATGGAGGAAG ATGGACTCAG GTGGACTCCA AAGTCTCCTC TGGACCCTGA CTCGGGCCTC 
CTTTCATGTA CTCTGCCCAA CGGTTTTGGG GGACAATCTG GGCCAGAAGG GGAGCGCAGC 
TTGGCACCCC CTGATGCCAG CATCCTCATC AGCAATGTGT GCAGCATCGG GGACCATGTG 
GCCCAGGAGC TTTTTCAGGG CTCAGATTTG GGCATGGCAG AAGAGGCAGA GAGGCCTGGG 
GAGAAAGCCG GCCAGCACAG CCCCCTGCGA GAGGAGCATG TGACCTGCGT ACAGAGCATC 
TTGGACGAAT TCCTTCAAAC GTATGGCAGC CTCATACCCC TCAGCACTGA TGAGGTAGTA 
GAGAAGCTGG AGGACATTTT CCAGCAGGAG TTTTCCACCC CTTCCAGGAA GGGCCTGGTG 
TTGCAGCTGA TCCAGTCTTA CCAGCGGATG CCAGGCAATG CCATGGTGAG GGGCTTCCGA 
GTGGCTTATA AGCGGCACGT GCTGACCATG GATGACTTGG GGACCTTGTA TGGACAGAAC 
TGGCTCAATG ACCAGGTGAT GAACATGTAT GGAGACCTGG TCATGGACAC AGTCCCTGAA 
AAGGTGCATT TCTTCAATAG TTTCTTCTAT GATAAACTCC GTACCAAGGG TTATGATGGG 
GTGAAAAGGT GGACCAAAAA CGTGGACATC TTCAATAAGG AGCTACTGCT AATCCCCATC 
CACCTGGAGG TGCATTGGTC CCTCATCTCT GTTGATGTGA GGCGACGCAC CATCACCTAT 
TTTGACTCGC AGCGTACCCT AAACCGCCGC TGCCCTAAGC ATATTGCCAA GTATCTACAG 
GCAGAGGCGG TAAAGAAAGA CCGACTGGAT TTCCACCAGG GCTGGAAAGG TTACTTCAAA 
ATGAATGTGG CCAGGCAGAA TAATGACAGT GACTGTGGTG CTTTTGTGTT GCAGTACTGC 
AAGCATCTGG CCCTGTCTCA GCCATTCAGC TTCACCCAGC AGGACATGCC CAAACTTCGT 
CGGCAGATCT ACAAGGAGCT GTGTCACTGC AAACTCACTG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056485.2
CDS	284..2008
Translation	MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV

Target ORF information:

RefSeq Version	NM_015670.5
Organism	Homo sapiens(human)
Definition	Homo sapiens SUMO1/sentrin/SMT3 specific peptidase 3 (SENP3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015670.5

ORF Insert Sequence:

ATGAAAGAGA CTATACAAGG GACCGGGTCC TGGGGGCCTG AGCCTCCTGG ACCCGGCATA 
CCCCCAGCTT ACTCAAGTCC CAGGCGGGAG CGTCTTCGTT GGCCCCCACC TCCCAAACCC 
CGACTCAAGT CAGGTGGAGG GTTTGGGCCA GATCCTGGGT CAGGGACCAC AGTGCCAGCC 
AGACGCCTCC CTGTCCCCCG ACCCTCTTTT GATGCCTCAG CAAGTGAAGA GGAGGAAGAA 
GAGGAGGAGG AGGAGGATGA AGATGAAGAG GAGGAAGTGG CAGCTTGGAG GCTGCCCCCA 
AGATGGAGTC AGCTGGGAAC CTCCCAGCGG CCCCGCCCTT CCCGCCCCAC TCATCGAAAA 
ACCTGCTCAC AGCGCCGCCG CCGAGCCATG AGAGCCTTCC GGATGCTGCT CTACTCAAAA 
AGCACCTCGC TGACATTCCA CTGGAAGCTT TGGGGGCGCC ACCGGGGCCG GCGGCGGGGC 
CTCGCACACC CCAAGAACCA TCTTTCACCC CAGCAAGGGG GTGCGACGCC ACAGGTGCCA 
TCCCCCTGTT GTCGTTTTGA CTCCCCCCGG GGGCCACCTC CACCCCGGCT GGGTCTGCTA 
GGTGCTCTCA TGGCTGAGGA TGGGGTGAGA GGGTCTCCAC CAGTGCCCTC TGGGCCCCCC 
ATGGAGGAAG ATGGACTCAG GTGGACTCCA AAGTCTCCTC TGGACCCTGA CTCGGGCCTC 
CTTTCATGTA CTCTGCCCAA CGGTTTTGGG GGACAATCTG GGCCAGAAGG GGAGCGCAGC 
TTGGCACCCC CTGATGCCAG CATCCTCATC AGCAATGTGT GCAGCATCGG GGACCATGTG 
GCCCAGGAGC TTTTTCAGGG CTCAGATTTG GGCATGGCAG AAGAGGCAGA GAGGCCTGGG 
GAGAAAGCCG GCCAGCACAG CCCCCTGCGA GAGGAGCATG TGACCTGCGT ACAGAGCATC 
TTGGACGAAT TCCTTCAAAC GTATGGCAGC CTCATACCCC TCAGCACTGA TGAGGTAGTA 
GAGAAGCTGG AGGACATTTT CCAGCAGGAG TTTTCCACCC CTTCCAGGAA GGGCCTGGTG 
TTGCAGCTGA TCCAGTCTTA CCAGCGGATG CCAGGCAATG CCATGGTGAG GGGCTTCCGA 
GTGGCTTATA AGCGGCACGT GCTGACCATG GATGACTTGG GGACCTTGTA TGGACAGAAC 
TGGCTCAATG ACCAGGTGAT GAACATGTAT GGAGACCTGG TCATGGACAC AGTCCCTGAA 
AAGGTGCATT TCTTCAATAG TTTCTTCTAT GATAAACTCC GTACCAAGGG TTATGATGGG 
GTGAAAAGGT GGACCAAAAA CGTGGACATC TTCAATAAGG AGCTACTGCT AATCCCCATC 
CACCTGGAGG TGCATTGGTC CCTCATCTCT GTTGATGTGA GGCGACGCAC CATCACCTAT 
TTTGACTCGC AGCGTACCCT AAACCGCCGC TGCCCTAAGC ATATTGCCAA GTATCTACAG 
GCAGAGGCGG TAAAGAAAGA CCGACTGGAT TTCCACCAGG GCTGGAAAGG TTACTTCAAA 
ATGAATGTGG CCAGGCAGAA TAATGACAGT GACTGTGGTG CTTTTGTGTT GCAGTACTGC 
AAGCATCTGG CCCTGTCTCA GCCATTCAGC TTCACCCAGC AGGACATGCC CAAACTTCGT 
CGGCAGATCT ACAAGGAGCT GTGTCACTGC AAACTCACTG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SENP3 ( NM_015670.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_056485.2 Homo sapiens SUMO specific peptidase 3 (SENP3), mRNA.

Price & Availability↑

CloneID	OHu09639
Clone ID Related Accession (Same CDS sequence)	NM_015670.5 , NM_015670.6
Accession Version	NM_015670.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	sentrin-specific protease 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC016876.10, BQ956948.1, BQ424754.1, CX165088.1, BC048306.1 and BF514106.1. On Nov 23, 2018 this sequence version replaced NM_015670.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.418579.1, SRR1163655.396429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000321337.12/ ENSP00000314029.8 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAAGAGA CTATACAAGG GACCGGGTCC TGGGGGCCTG AGCCTCCTGG ACCCGGCATA 
CCCCCAGCTT ACTCAAGTCC CAGGCGGGAG CGTCTTCGTT GGCCCCCACC TCCCAAACCC 
CGACTCAAGT CAGGTGGAGG GTTTGGGCCA GATCCTGGGT CAGGGACCAC AGTGCCAGCC 
AGACGCCTCC CTGTCCCCCG ACCCTCTTTT GATGCCTCAG CAAGTGAAGA GGAGGAAGAA 
GAGGAGGAGG AGGAGGATGA AGATGAAGAG GAGGAAGTGG CAGCTTGGAG GCTGCCCCCA 
AGATGGAGTC AGCTGGGAAC CTCCCAGCGG CCCCGCCCTT CCCGCCCCAC TCATCGAAAA 
ACCTGCTCAC AGCGCCGCCG CCGAGCCATG AGAGCCTTCC GGATGCTGCT CTACTCAAAA 
AGCACCTCGC TGACATTCCA CTGGAAGCTT TGGGGGCGCC ACCGGGGCCG GCGGCGGGGC 
CTCGCACACC CCAAGAACCA TCTTTCACCC CAGCAAGGGG GTGCGACGCC ACAGGTGCCA 
TCCCCCTGTT GTCGTTTTGA CTCCCCCCGG GGGCCACCTC CACCCCGGCT GGGTCTGCTA 
GGTGCTCTCA TGGCTGAGGA TGGGGTGAGA GGGTCTCCAC CAGTGCCCTC TGGGCCCCCC 
ATGGAGGAAG ATGGACTCAG GTGGACTCCA AAGTCTCCTC TGGACCCTGA CTCGGGCCTC 
CTTTCATGTA CTCTGCCCAA CGGTTTTGGG GGACAATCTG GGCCAGAAGG GGAGCGCAGC 
TTGGCACCCC CTGATGCCAG CATCCTCATC AGCAATGTGT GCAGCATCGG GGACCATGTG 
GCCCAGGAGC TTTTTCAGGG CTCAGATTTG GGCATGGCAG AAGAGGCAGA GAGGCCTGGG 
GAGAAAGCCG GCCAGCACAG CCCCCTGCGA GAGGAGCATG TGACCTGCGT ACAGAGCATC 
TTGGACGAAT TCCTTCAAAC GTATGGCAGC CTCATACCCC TCAGCACTGA TGAGGTAGTA 
GAGAAGCTGG AGGACATTTT CCAGCAGGAG TTTTCCACCC CTTCCAGGAA GGGCCTGGTG 
TTGCAGCTGA TCCAGTCTTA CCAGCGGATG CCAGGCAATG CCATGGTGAG GGGCTTCCGA 
GTGGCTTATA AGCGGCACGT GCTGACCATG GATGACTTGG GGACCTTGTA TGGACAGAAC 
TGGCTCAATG ACCAGGTGAT GAACATGTAT GGAGACCTGG TCATGGACAC AGTCCCTGAA 
AAGGTGCATT TCTTCAATAG TTTCTTCTAT GATAAACTCC GTACCAAGGG TTATGATGGG 
GTGAAAAGGT GGACCAAAAA CGTGGACATC TTCAATAAGG AGCTACTGCT AATCCCCATC 
CACCTGGAGG TGCATTGGTC CCTCATCTCT GTTGATGTGA GGCGACGCAC CATCACCTAT 
TTTGACTCGC AGCGTACCCT AAACCGCCGC TGCCCTAAGC ATATTGCCAA GTATCTACAG 
GCAGAGGCGG TAAAGAAAGA CCGACTGGAT TTCCACCAGG GCTGGAAAGG TTACTTCAAA 
ATGAATGTGG CCAGGCAGAA TAATGACAGT GACTGTGGTG CTTTTGTGTT GCAGTACTGC 
AAGCATCTGG CCCTGTCTCA GCCATTCAGC TTCACCCAGC AGGACATGCC CAAACTTCGT 
CGGCAGATCT ACAAGGAGCT GTGTCACTGC AAACTCACTG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056485.2
CDS	357..2081
Translation	MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV

Target ORF information:

RefSeq Version	NM_015670.6
Organism	Homo sapiens(human)
Definition	Homo sapiens SUMO specific peptidase 3 (SENP3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015670.6

ORF Insert Sequence:

ATGAAAGAGA CTATACAAGG GACCGGGTCC TGGGGGCCTG AGCCTCCTGG ACCCGGCATA 
CCCCCAGCTT ACTCAAGTCC CAGGCGGGAG CGTCTTCGTT GGCCCCCACC TCCCAAACCC 
CGACTCAAGT CAGGTGGAGG GTTTGGGCCA GATCCTGGGT CAGGGACCAC AGTGCCAGCC 
AGACGCCTCC CTGTCCCCCG ACCCTCTTTT GATGCCTCAG CAAGTGAAGA GGAGGAAGAA 
GAGGAGGAGG AGGAGGATGA AGATGAAGAG GAGGAAGTGG CAGCTTGGAG GCTGCCCCCA 
AGATGGAGTC AGCTGGGAAC CTCCCAGCGG CCCCGCCCTT CCCGCCCCAC TCATCGAAAA 
ACCTGCTCAC AGCGCCGCCG CCGAGCCATG AGAGCCTTCC GGATGCTGCT CTACTCAAAA 
AGCACCTCGC TGACATTCCA CTGGAAGCTT TGGGGGCGCC ACCGGGGCCG GCGGCGGGGC 
CTCGCACACC CCAAGAACCA TCTTTCACCC CAGCAAGGGG GTGCGACGCC ACAGGTGCCA 
TCCCCCTGTT GTCGTTTTGA CTCCCCCCGG GGGCCACCTC CACCCCGGCT GGGTCTGCTA 
GGTGCTCTCA TGGCTGAGGA TGGGGTGAGA GGGTCTCCAC CAGTGCCCTC TGGGCCCCCC 
ATGGAGGAAG ATGGACTCAG GTGGACTCCA AAGTCTCCTC TGGACCCTGA CTCGGGCCTC 
CTTTCATGTA CTCTGCCCAA CGGTTTTGGG GGACAATCTG GGCCAGAAGG GGAGCGCAGC 
TTGGCACCCC CTGATGCCAG CATCCTCATC AGCAATGTGT GCAGCATCGG GGACCATGTG 
GCCCAGGAGC TTTTTCAGGG CTCAGATTTG GGCATGGCAG AAGAGGCAGA GAGGCCTGGG 
GAGAAAGCCG GCCAGCACAG CCCCCTGCGA GAGGAGCATG TGACCTGCGT ACAGAGCATC 
TTGGACGAAT TCCTTCAAAC GTATGGCAGC CTCATACCCC TCAGCACTGA TGAGGTAGTA 
GAGAAGCTGG AGGACATTTT CCAGCAGGAG TTTTCCACCC CTTCCAGGAA GGGCCTGGTG 
TTGCAGCTGA TCCAGTCTTA CCAGCGGATG CCAGGCAATG CCATGGTGAG GGGCTTCCGA 
GTGGCTTATA AGCGGCACGT GCTGACCATG GATGACTTGG GGACCTTGTA TGGACAGAAC 
TGGCTCAATG ACCAGGTGAT GAACATGTAT GGAGACCTGG TCATGGACAC AGTCCCTGAA 
AAGGTGCATT TCTTCAATAG TTTCTTCTAT GATAAACTCC GTACCAAGGG TTATGATGGG 
GTGAAAAGGT GGACCAAAAA CGTGGACATC TTCAATAAGG AGCTACTGCT AATCCCCATC 
CACCTGGAGG TGCATTGGTC CCTCATCTCT GTTGATGTGA GGCGACGCAC CATCACCTAT 
TTTGACTCGC AGCGTACCCT AAACCGCCGC TGCCCTAAGC ATATTGCCAA GTATCTACAG 
GCAGAGGCGG TAAAGAAAGA CCGACTGGAT TTCCACCAGG GCTGGAAAGG TTACTTCAAA 
ATGAATGTGG CCAGGCAGAA TAATGACAGT GACTGTGGTG CTTTTGTGTT GCAGTACTGC 
AAGCATCTGG CCCTGTCTCA GCCATTCAGC TTCACCCAGC AGGACATGCC CAAACTTCGT 
CGGCAGATCT ACAAGGAGCT GTGTCACTGC AAACTCACTG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased SUMO-2/3-ylation mediated by SENP3 degradation is protective against cadmium-induced caspase 3-dependent cytotoxicity.
The Journal of toxicological sciences42(5)529-538(2017)
Luo J,Gurung S,Lee L,Henley JM,Wilkinson KA,Guo C

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SENP3 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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