KIFBP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KIFBP
Entrez Gene ID	26128
Full Name	KIF1 binding protein
Synonyms	KBP,KIAA1279,TTC20
General protein information	Preferred Names KIF1 binding protein Names KIF1-binding protein kinesin binding protein mutant KIF1 binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q22.1
Summary	This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratrico peptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating transport of the mitochondria. Mutations in this gene are associated with Goldberg-Shprintzen megacolon syndrome. [provided by RefSeq, Mar 2010].
Disorder MIM:	609367
Disorder Html:	Goldberg-Shprintzen megacolon syndrome, 609460 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_015634.3	NP_056449.1	KIF1-binding protein
XM_017016067.1	XP_016871556.1	KIF-binding protein isoform X1
NM_015634.4	NP_056449.1	KIF-binding protein

Pathways from BioSystems

Homologies

Homo sapiens (human)	KIAA1279	NP_056449.1
Bos taurus (cattle)	KIAA1279	NP_001029731.1
Gallus gallus (chicken)	KIAA1279	NP_001007945.1
Pan troglodytes (chimpanzee)	KIAA1279	XP_507827.3
Drosophila melanogaster (fruit fly)	CG14043	NP_608886.1
Mus musculus (house mouse)	2510003E04Rik	NP_082473.2
Rattus norvegicus (Norway rat)	LOC606294	NP_001026797.1
	LOC717469	XP_002805751.1
Canis lupus familiaris (dog)	KIAA1279	XP_536374.3
Xenopus tropicalis (tropical clawed frog)	kiaa1279	NP_001072796.1
Danio rerio (zebrafish)	kbp	NP_001013480.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009536	XP_559710.2

Gene Ontology
Bibliography

Related articles in PubMed

Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment.
Brouwers N, Mallol Martinez N, Vernos I
PloS one12(4)e0174819(2017)

Association of a Novel Nonsense Mutation in KIAA1279 with Goldberg-Shprintzen Syndrome.
Salehpour S, Hashemi-Gorji F, Soltani Z, Ghafouri-Fard S, Miryounesi M
Iranian journal of child neurology11(1)70-74(2017)

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity.
Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J, Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, de Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC
Current biology : CB26(7)849-61(2016 Apr)

Homozygous truncating mutation of the KBP gene, encoding a KIF1B-binding protein, in a familial case of fetal polymicrogyria.
Valence S, Poirier K, Lebrun N, Saillour Y, Sonigo P, Bessi?res B, Atti?-Bitach T, Benachi A, Masson C, Encha-Razavi F, Chelly J, Bahi-Buisson N
Neurogenetics14(3-4)215-24(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Both Kif15 and KBP are required for the alignment of all the chromosomes to the metaphase plate and the assembly of stable kinetochore fibers of the correct length.
Title: Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment.

Data suggest that KBP functions as a kinesin inhibitor that modulates MT-based cargo motility and depolymerizing activity of a subset of kinesin motors. We propose that misregulation of KBP-controlled kinesin motors may represent the underlying molecular mechanism that contributes to the neuropathological defects observed in Goldberg-Shprintzen syndrome patients.
Title: Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity.

A report on fetal cases with a homozygous mutation in KBP gene in a consanguineous Pakistani family with isolated polymicrogyria.
Title: Homozygous truncating mutation of the KBP gene, encoding a KIF1B-binding protein, in a familial case of fetal polymicrogyria.

KBP-cytoskeleton interactions is involved in neuronal development in Goldberg-Shprintzen syndrome.
Title: KBP-cytoskeleton interactions underlie developmental anomalies in Goldberg-Shprintzen syndrome.

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The following KIFBP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KIFBP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26093	NM_015634.4 Latest version!	Homo sapiens kinesin family binding protein (KIFBP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$259.50-$363.30 $519.00
OHu91295	XM_017016067.1 Latest version!	Homo sapiens kinesin family binding protein (KIFBP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu26093	NM_015634.3	Homo sapiens KIF1 binding protein (KIF1BP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$259.50-$363.30 $519.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KIFBP ( NM_015634.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056449.1 Homo sapiens KIF1 binding protein (KIF1BP), mRNA.

Price & Availability↑

CloneID	OHu26093
Clone ID Related Accession (Same CDS sequence)	NM_015634.3 , NM_015634.4
Accession Version	NM_015634.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	KIF1-binding protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA292451.1, BC006427.1, AL050190.1 and AI491993.1. This sequence is a reference standard in the RefSeqGene project. On Mar 18, 2010 this sequence version replaced NM_015634.2. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.228406.1, SRR1803616.174367.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACG TTCCGTGGGC AGAGGTCTGC GAGAAATTCC AGGCGGCGCT CGCTCTGTCG 
CGGGTGGAAC TGCATAAAAA TCCGGAGAAG GAACCATACA AGTCCAAATA CAGCGCCCGG 
GCGCTACTGG AAGAGGTCAA GGCGCTGCTC GGCCCTGCGC CTGAGGACGA GGATGAGCGG 
CCTGAGGCCG AGGACGGCCC GGGTGCCGGT GACCACGCCC TGGGGCTGCC GGCTGAGGTG 
GTGGAGCCCG AGGGGCCCGT CGCCCAGCGA GCGGTGAGGC TGGCAGTCAT CGAGTTCCAC 
CTCGGGGTGA ACCACATCGA CACGGAGGAG CTGTCGGCGG GGGAGGAGCA CCTGGTGAAA 
TGCCTGCGGC TGCTGCGCAG GTACCGGCTC TCGCACGACT GCATCTCTCT CTGCATCCAG 
GCGCAGAATA ACCTGGGTAT CTTGTGGTCT GAAAGAGAAG AAATTGAAAC TGCACAGGCT 
TACCTAGAGT CATCAGAAGC ACTATATAAT CAGTATATGA AAGAGGTTGG GAGTCCTCCT 
CTTGATCCTA CTGAGCGTTT TCTTCCTGAA GAAGAGAAAC TTACTGAACA AGAGAGATCA 
AAAAGATTTG AAAAGGTTTA TACTCATAAC CTATATTACC TAGCTCAAGT CTACCAGCAT 
CTGGAAATGT TTGAGAAGGC TGCTCACTAT TGCCATAGTA CACTAAAACG CCAGCTTGAG 
CACAATGCCT ACCATCCTAT AGAGTGGGCT ATCAATGCTG CTACCTTGTC ACAGTTTTAC 
ATCAATAAGC TATGCTTTAT GGAGGCCAGG CACTGTTTAT CAGCTGCTAA TGTCATTTTT 
GGTCAAACTG GAAAGATCTC AGCCACAGAA GACACTCCTG AAGCTGAAGG AGAAGTGCCA 
GAGCTTTATC ATCAAAGAAA GGGGGAAATA GCAAGGTGCT GGATCAAATA CTGTTTGACT 
CTCATGCAGA ATGCCCAACT CTCCATGCAG GACAACATAG GAGAGCTTGA TCTTGATAAA 
CAGTCTGAAC TTAGAGCTTT AAGGAAAAAA GAACTAGATG AGGAGGAAAG CATTCGGAAA 
AAAGCTGTGC AGTTTGGAAC CGGTGAACTG TGTGATGCCA TCTCTGCAGT AGAAGAGAAA 
GTGAGCTACT TGAGACCTTT AGATTTTGAA GAAGCCAGAG AACTTTTCTT ATTGGGTCAG 
CACTATGTCT TTGAGGCAAA AGAGTTCTTT CAGATTGATG GTTATGTCAC TGACCATATT 
GAAGTTGTCC AAGACCACAG TGCTCTGTTT AAGGTGCTTG CATTCTTTGA AACTGACATG 
GAGAGACGGT GCAAGATGCA TAAACGCAGA ATAGCCATGC TAGAGCCCCT AACTGTAGAC 
CTGAATCCAC AGTATTATCT GTTGGTCAAC AGACAGATCC AGTTTGAAAT TGCACATGCT 
TACTATGATA TGATGGATTT GAAGGTTGCC ATTGCTGACA GGCTAAGGGA TCCTGATTCA 
CACATTGTAA AAAAAATAAA TAATCTTAAT AAGTCAGCAC TGAAGTACTA CCAGCTCTTC 
TTAGACTCCC TGAGAGACCC AAATAAAGTA TTCCCTGAGC ATATAGGGGA AGATGTTCTT 
CGCCCTGCCA TGTTAGCTAA GTTTCGAGTT GCCCGTCTCT ATGGCAAAAT CATTACTGCA 
GATCCCAAGA AAGAGCTGGA AAATTTGGCA ACATCATTGG AACATTACAA ATTTATTGTT 
GATTACTGTG AAAAGCATCC TGAGGCCGCC CAGGAAATAG AAGTTGAGCT AGAACTTAGT 
AAAGAGATGG TTAGTCTTCT CCCAACAAAA ATGGAGAGAT TCAGAACCAA GATGGCCCTG 
ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056449.1
CDS	113..1978
Translation	MANVPWAEVCEKFQAALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPEAEDGPGAGDHALGLPAEVVEPEGPVAQRAVRLAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRRYRLSHDCISLCIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEVGSPPLDPTERFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHLEMFEKAAHYCHSTLKRQLEHNAYHPIEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT

Target ORF information:

RefSeq Version	NM_015634.3
Organism	Homo sapiens(human)
Definition	Homo sapiens KIF1 binding protein (KIF1BP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015634.3

ORF Insert Sequence:

ATGGCGAACG TTCCGTGGGC AGAGGTCTGC GAGAAATTCC AGGCGGCGCT CGCTCTGTCG 
CGGGTGGAAC TGCATAAAAA TCCGGAGAAG GAACCATACA AGTCCAAATA CAGCGCCCGG 
GCGCTACTGG AAGAGGTCAA GGCGCTGCTC GGCCCTGCGC CTGAGGACGA GGATGAGCGG 
CCTGAGGCCG AGGACGGCCC GGGTGCCGGT GACCACGCCC TGGGGCTGCC GGCTGAGGTG 
GTGGAGCCCG AGGGGCCCGT CGCCCAGCGA GCGGTGAGGC TGGCAGTCAT CGAGTTCCAC 
CTCGGGGTGA ACCACATCGA CACGGAGGAG CTGTCGGCGG GGGAGGAGCA CCTGGTGAAA 
TGCCTGCGGC TGCTGCGCAG GTACCGGCTC TCGCACGACT GCATCTCTCT CTGCATCCAG 
GCGCAGAATA ACCTGGGTAT CTTGTGGTCT GAAAGAGAAG AAATTGAAAC TGCACAGGCT 
TACCTAGAGT CATCAGAAGC ACTATATAAT CAGTATATGA AAGAGGTTGG GAGTCCTCCT 
CTTGATCCTA CTGAGCGTTT TCTTCCTGAA GAAGAGAAAC TTACTGAACA AGAGAGATCA 
AAAAGATTTG AAAAGGTTTA TACTCATAAC CTATATTACC TAGCTCAAGT CTACCAGCAT 
CTGGAAATGT TTGAGAAGGC TGCTCACTAT TGCCATAGTA CACTAAAACG CCAGCTTGAG 
CACAATGCCT ACCATCCTAT AGAGTGGGCT ATCAATGCTG CTACCTTGTC ACAGTTTTAC 
ATCAATAAGC TATGCTTTAT GGAGGCCAGG CACTGTTTAT CAGCTGCTAA TGTCATTTTT 
GGTCAAACTG GAAAGATCTC AGCCACAGAA GACACTCCTG AAGCTGAAGG AGAAGTGCCA 
GAGCTTTATC ATCAAAGAAA GGGGGAAATA GCAAGGTGCT GGATCAAATA CTGTTTGACT 
CTCATGCAGA ATGCCCAACT CTCCATGCAG GACAACATAG GAGAGCTTGA TCTTGATAAA 
CAGTCTGAAC TTAGAGCTTT AAGGAAAAAA GAACTAGATG AGGAGGAAAG CATTCGGAAA 
AAAGCTGTGC AGTTTGGAAC CGGTGAACTG TGTGATGCCA TCTCTGCAGT AGAAGAGAAA 
GTGAGCTACT TGAGACCTTT AGATTTTGAA GAAGCCAGAG AACTTTTCTT ATTGGGTCAG 
CACTATGTCT TTGAGGCAAA AGAGTTCTTT CAGATTGATG GTTATGTCAC TGACCATATT 
GAAGTTGTCC AAGACCACAG TGCTCTGTTT AAGGTGCTTG CATTCTTTGA AACTGACATG 
GAGAGACGGT GCAAGATGCA TAAACGCAGA ATAGCCATGC TAGAGCCCCT AACTGTAGAC 
CTGAATCCAC AGTATTATCT GTTGGTCAAC AGACAGATCC AGTTTGAAAT TGCACATGCT 
TACTATGATA TGATGGATTT GAAGGTTGCC ATTGCTGACA GGCTAAGGGA TCCTGATTCA 
CACATTGTAA AAAAAATAAA TAATCTTAAT AAGTCAGCAC TGAAGTACTA CCAGCTCTTC 
TTAGACTCCC TGAGAGACCC AAATAAAGTA TTCCCTGAGC ATATAGGGGA AGATGTTCTT 
CGCCCTGCCA TGTTAGCTAA GTTTCGAGTT GCCCGTCTCT ATGGCAAAAT CATTACTGCA 
GATCCCAAGA AAGAGCTGGA AAATTTGGCA ACATCATTGG AACATTACAA ATTTATTGTT 
GATTACTGTG AAAAGCATCC TGAGGCCGCC CAGGAAATAG AAGTTGAGCT AGAACTTAGT 
AAAGAGATGG TTAGTCTTCT CCCAACAAAA ATGGAGAGAT TCAGAACCAA GATGGCCCTG 
ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIFBP ( NM_015634.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056449.1 Homo sapiens kinesin family binding protein (KIFBP), mRNA.

Price & Availability↑

CloneID	OHu26093
Clone ID Related Accession (Same CDS sequence)	NM_015634.3 , NM_015634.4
Accession Version	NM_015634.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-21
Organism	Homo sapiens(human)
Product	KIF-binding protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA292451.1, BC006427.1 and AL050190.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_015634.3. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.677431.1, SRR3476690.378913.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology MANE Ensembl match :: ENST00000361983.7/ ENSP00000354848.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGAACG TTCCGTGGGC AGAGGTCTGC GAGAAATTCC AGGCGGCGCT CGCTCTGTCG 
CGGGTGGAAC TGCATAAAAA TCCGGAGAAG GAACCATACA AGTCCAAATA CAGCGCCCGG 
GCGCTACTGG AAGAGGTCAA GGCGCTGCTC GGCCCTGCGC CTGAGGACGA GGATGAGCGG 
CCTGAGGCCG AGGACGGCCC GGGTGCCGGT GACCACGCCC TGGGGCTGCC GGCTGAGGTG 
GTGGAGCCCG AGGGGCCCGT CGCCCAGCGA GCGGTGAGGC TGGCAGTCAT CGAGTTCCAC 
CTCGGGGTGA ACCACATCGA CACGGAGGAG CTGTCGGCGG GGGAGGAGCA CCTGGTGAAA 
TGCCTGCGGC TGCTGCGCAG GTACCGGCTC TCGCACGACT GCATCTCTCT CTGCATCCAG 
GCGCAGAATA ACCTGGGTAT CTTGTGGTCT GAAAGAGAAG AAATTGAAAC TGCACAGGCT 
TACCTAGAGT CATCAGAAGC ACTATATAAT CAGTATATGA AAGAGGTTGG GAGTCCTCCT 
CTTGATCCTA CTGAGCGTTT TCTTCCTGAA GAAGAGAAAC TTACTGAACA AGAGAGATCA 
AAAAGATTTG AAAAGGTTTA TACTCATAAC CTATATTACC TAGCTCAAGT CTACCAGCAT 
CTGGAAATGT TTGAGAAGGC TGCTCACTAT TGCCATAGTA CACTAAAACG CCAGCTTGAG 
CACAATGCCT ACCATCCTAT AGAGTGGGCT ATCAATGCTG CTACCTTGTC ACAGTTTTAC 
ATCAATAAGC TATGCTTTAT GGAGGCCAGG CACTGTTTAT CAGCTGCTAA TGTCATTTTT 
GGTCAAACTG GAAAGATCTC AGCCACAGAA GACACTCCTG AAGCTGAAGG AGAAGTGCCA 
GAGCTTTATC ATCAAAGAAA GGGGGAAATA GCAAGGTGCT GGATCAAATA CTGTTTGACT 
CTCATGCAGA ATGCCCAACT CTCCATGCAG GACAACATAG GAGAGCTTGA TCTTGATAAA 
CAGTCTGAAC TTAGAGCTTT AAGGAAAAAA GAACTAGATG AGGAGGAAAG CATTCGGAAA 
AAAGCTGTGC AGTTTGGAAC CGGTGAACTG TGTGATGCCA TCTCTGCAGT AGAAGAGAAA 
GTGAGCTACT TGAGACCTTT AGATTTTGAA GAAGCCAGAG AACTTTTCTT ATTGGGTCAG 
CACTATGTCT TTGAGGCAAA AGAGTTCTTT CAGATTGATG GTTATGTCAC TGACCATATT 
GAAGTTGTCC AAGACCACAG TGCTCTGTTT AAGGTGCTTG CATTCTTTGA AACTGACATG 
GAGAGACGGT GCAAGATGCA TAAACGCAGA ATAGCCATGC TAGAGCCCCT AACTGTAGAC 
CTGAATCCAC AGTATTATCT GTTGGTCAAC AGACAGATCC AGTTTGAAAT TGCACATGCT 
TACTATGATA TGATGGATTT GAAGGTTGCC ATTGCTGACA GGCTAAGGGA TCCTGATTCA 
CACATTGTAA AAAAAATAAA TAATCTTAAT AAGTCAGCAC TGAAGTACTA CCAGCTCTTC 
TTAGACTCCC TGAGAGACCC AAATAAAGTA TTCCCTGAGC ATATAGGGGA AGATGTTCTT 
CGCCCTGCCA TGTTAGCTAA GTTTCGAGTT GCCCGTCTCT ATGGCAAAAT CATTACTGCA 
GATCCCAAGA AAGAGCTGGA AAATTTGGCA ACATCATTGG AACATTACAA ATTTATTGTT 
GATTACTGTG AAAAGCATCC TGAGGCCGCC CAGGAAATAG AAGTTGAGCT AGAACTTAGT 
AAAGAGATGG TTAGTCTTCT CCCAACAAAA ATGGAGAGAT TCAGAACCAA GATGGCCCTG 
ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056449.1
CDS	31..1896
Translation	MANVPWAEVCEKFQAALALSRVELHKNPEKEPYKSKYSARALLEEVKALLGPAPEDEDERPEAEDGPGAGDHALGLPAEVVEPEGPVAQRAVRLAVIEFHLGVNHIDTEELSAGEEHLVKCLRLLRRYRLSHDCISLCIQAQNNLGILWSEREEIETAQAYLESSEALYNQYMKEVGSPPLDPTERFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHLEMFEKAAHYCHSTLKRQLEHNAYHPIEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT

Target ORF information:

RefSeq Version	NM_015634.4
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family binding protein (KIFBP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015634.4

ORF Insert Sequence:

ATGGCGAACG TTCCGTGGGC AGAGGTCTGC GAGAAATTCC AGGCGGCGCT CGCTCTGTCG 
CGGGTGGAAC TGCATAAAAA TCCGGAGAAG GAACCATACA AGTCCAAATA CAGCGCCCGG 
GCGCTACTGG AAGAGGTCAA GGCGCTGCTC GGCCCTGCGC CTGAGGACGA GGATGAGCGG 
CCTGAGGCCG AGGACGGCCC GGGTGCCGGT GACCACGCCC TGGGGCTGCC GGCTGAGGTG 
GTGGAGCCCG AGGGGCCCGT CGCCCAGCGA GCGGTGAGGC TGGCAGTCAT CGAGTTCCAC 
CTCGGGGTGA ACCACATCGA CACGGAGGAG CTGTCGGCGG GGGAGGAGCA CCTGGTGAAA 
TGCCTGCGGC TGCTGCGCAG GTACCGGCTC TCGCACGACT GCATCTCTCT CTGCATCCAG 
GCGCAGAATA ACCTGGGTAT CTTGTGGTCT GAAAGAGAAG AAATTGAAAC TGCACAGGCT 
TACCTAGAGT CATCAGAAGC ACTATATAAT CAGTATATGA AAGAGGTTGG GAGTCCTCCT 
CTTGATCCTA CTGAGCGTTT TCTTCCTGAA GAAGAGAAAC TTACTGAACA AGAGAGATCA 
AAAAGATTTG AAAAGGTTTA TACTCATAAC CTATATTACC TAGCTCAAGT CTACCAGCAT 
CTGGAAATGT TTGAGAAGGC TGCTCACTAT TGCCATAGTA CACTAAAACG CCAGCTTGAG 
CACAATGCCT ACCATCCTAT AGAGTGGGCT ATCAATGCTG CTACCTTGTC ACAGTTTTAC 
ATCAATAAGC TATGCTTTAT GGAGGCCAGG CACTGTTTAT CAGCTGCTAA TGTCATTTTT 
GGTCAAACTG GAAAGATCTC AGCCACAGAA GACACTCCTG AAGCTGAAGG AGAAGTGCCA 
GAGCTTTATC ATCAAAGAAA GGGGGAAATA GCAAGGTGCT GGATCAAATA CTGTTTGACT 
CTCATGCAGA ATGCCCAACT CTCCATGCAG GACAACATAG GAGAGCTTGA TCTTGATAAA 
CAGTCTGAAC TTAGAGCTTT AAGGAAAAAA GAACTAGATG AGGAGGAAAG CATTCGGAAA 
AAAGCTGTGC AGTTTGGAAC CGGTGAACTG TGTGATGCCA TCTCTGCAGT AGAAGAGAAA 
GTGAGCTACT TGAGACCTTT AGATTTTGAA GAAGCCAGAG AACTTTTCTT ATTGGGTCAG 
CACTATGTCT TTGAGGCAAA AGAGTTCTTT CAGATTGATG GTTATGTCAC TGACCATATT 
GAAGTTGTCC AAGACCACAG TGCTCTGTTT AAGGTGCTTG CATTCTTTGA AACTGACATG 
GAGAGACGGT GCAAGATGCA TAAACGCAGA ATAGCCATGC TAGAGCCCCT AACTGTAGAC 
CTGAATCCAC AGTATTATCT GTTGGTCAAC AGACAGATCC AGTTTGAAAT TGCACATGCT 
TACTATGATA TGATGGATTT GAAGGTTGCC ATTGCTGACA GGCTAAGGGA TCCTGATTCA 
CACATTGTAA AAAAAATAAA TAATCTTAAT AAGTCAGCAC TGAAGTACTA CCAGCTCTTC 
TTAGACTCCC TGAGAGACCC AAATAAAGTA TTCCCTGAGC ATATAGGGGA AGATGTTCTT 
CGCCCTGCCA TGTTAGCTAA GTTTCGAGTT GCCCGTCTCT ATGGCAAAAT CATTACTGCA 
GATCCCAAGA AAGAGCTGGA AAATTTGGCA ACATCATTGG AACATTACAA ATTTATTGTT 
GATTACTGTG AAAAGCATCC TGAGGCCGCC CAGGAAATAG AAGTTGAGCT AGAACTTAGT 
AAAGAGATGG TTAGTCTTCT CCCAACAAAA ATGGAGAGAT TCAGAACCAA GATGGCCCTG 
ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIFBP ( XM_017016067.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016871556.1 Homo sapiens kinesin family binding protein (KIFBP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu91295
Clone ID Related Accession (Same CDS sequence)	XM_017016067.1
Accession Version	XM_017016067.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	KIF-binding protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCCA GGCACTGTTT ATCAGCTGCT AATGTCATTT TTGGTCAAAC TGGAAAGATC 
TCAGCCACAG AAGACACTCC TGAAGCTGAA GGAGAAGTGC CAGAGCTTTA TCATCAAAGA 
AAGGGGGAAA TAGCAAGGTG CTGGATCAAA TACTGTTTGA CTCTCATGCA GAATGCCCAA 
CTCTCCATGC AGGACAACAT AGGAGAGCTT GATCTTGATA AACAGTCTGA ACTTAGAGCT 
TTAAGGAAAA AAGAACTAGA TGAGGAGGAA AGCATTCGGA AAAAAGCTGT GCAGTTTGGA 
ACCGGTGAAC TGTGTGATGC CATCTCTGCA GTAGAAGAGA AAGTGAGCTA CTTGAGACCT 
TTAGATTTTG AAGAAGCCAG AGAACTTTTC TTATTGGGTC AGCACTATGT CTTTGAGGCA 
AAAGAGTTCT TTCAGATTGA TGGTTATGTC ACTGACCATA TTGAAGTTGT CCAAGACCAC 
AGTGCTCTGT TTAAGGTGCT TGCATTCTTT GAAACTGACA TGGAGAGACG GTGCAAGATG 
CATAAACGCA GAATAGCCAT GCTAGAGCCC CTAACTGTAG ACCTGAATCC ACAGTATTAT 
CTGTTGGTCA ACAGACAGAT CCAGTTTGAA ATTGCACATG CTTACTATGA TATGATGGAT 
TTGAAGGTTG CCATTGCTGA CAGGCTAAGG GATCCTGATT CACACATTGT AAAAAAAATA 
AATAATCTTA ATAAGTCAGC ACTGAAGTAC TACCAGCTCT TCTTAGACTC CCTGAGAGAC 
CCAAATAAAG TATTCCCTGA GCATATAGGG GAAGATGTTC TTCGCCCTGC CATGTTAGCT 
AAGTTTCGAG TTGCCCGTCT CTATGGCAAA ATCATTACTG CAGATCCCAA GAAAGAGCTG 
GAAAATTTGG CAACATCATT GGAACATTAC AAATTTATTG TTGATTACTG TGAAAAGCAT 
CCTGAGGCCG CCCAGGAAAT AGAAGTTGAG CTAGAACTTA GTAAAGAGAT GGTTAGTCTT 
CTCCCAACAA AAATGGAGAG ATTCAGAACC AAGATGGCCC TGACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016871556.1
CDS	1435..2502
Translation	MEARHCLSAANVIFGQTGKISATEDTPEAEGEVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESIRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARELFLLGQHYVFEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFETDMERRCKMHKRRIAMLEPLTVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADRLRDPDSHIVKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCEKHPEAAQEIEVELELSKEMVSLLPTKMERFRTKMALT

Target ORF information:

RefSeq Version	XM_017016067.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family binding protein (KIFBP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016067.1

ORF Insert Sequence:

ATGGAGGCCA GGCACTGTTT ATCAGCTGCT AATGTCATTT TTGGTCAAAC TGGAAAGATC 
TCAGCCACAG AAGACACTCC TGAAGCTGAA GGAGAAGTGC CAGAGCTTTA TCATCAAAGA 
AAGGGGGAAA TAGCAAGGTG CTGGATCAAA TACTGTTTGA CTCTCATGCA GAATGCCCAA 
CTCTCCATGC AGGACAACAT AGGAGAGCTT GATCTTGATA AACAGTCTGA ACTTAGAGCT 
TTAAGGAAAA AAGAACTAGA TGAGGAGGAA AGCATTCGGA AAAAAGCTGT GCAGTTTGGA 
ACCGGTGAAC TGTGTGATGC CATCTCTGCA GTAGAAGAGA AAGTGAGCTA CTTGAGACCT 
TTAGATTTTG AAGAAGCCAG AGAACTTTTC TTATTGGGTC AGCACTATGT CTTTGAGGCA 
AAAGAGTTCT TTCAGATTGA TGGTTATGTC ACTGACCATA TTGAAGTTGT CCAAGACCAC 
AGTGCTCTGT TTAAGGTGCT TGCATTCTTT GAAACTGACA TGGAGAGACG GTGCAAGATG 
CATAAACGCA GAATAGCCAT GCTAGAGCCC CTAACTGTAG ACCTGAATCC ACAGTATTAT 
CTGTTGGTCA ACAGACAGAT CCAGTTTGAA ATTGCACATG CTTACTATGA TATGATGGAT 
TTGAAGGTTG CCATTGCTGA CAGGCTAAGG GATCCTGATT CACACATTGT AAAAAAAATA 
AATAATCTTA ATAAGTCAGC ACTGAAGTAC TACCAGCTCT TCTTAGACTC CCTGAGAGAC 
CCAAATAAAG TATTCCCTGA GCATATAGGG GAAGATGTTC TTCGCCCTGC CATGTTAGCT 
AAGTTTCGAG TTGCCCGTCT CTATGGCAAA ATCATTACTG CAGATCCCAA GAAAGAGCTG 
GAAAATTTGG CAACATCATT GGAACATTAC AAATTTATTG TTGATTACTG TGAAAAGCAT 
CCTGAGGCCG CCCAGGAAAT AGAAGTTGAG CTAGAACTTA GTAAAGAGAT GGTTAGTCTT 
CTCCCAACAA AAATGGAGAG ATTCAGAACC AAGATGGCCC TGACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment.
PloS one12(4)e0174819(2017)
Brouwers N,Mallol Martinez N,Vernos I

Association of a Novel Nonsense Mutation in KIAA1279 with Goldberg-Shprintzen Syndrome.
ian journal of child neurology11(1)70-74(2017)
Salehpour S,Hashemi-Gorji F,Soltani Z,Ghafouri-Fard S,Miryounesi M

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity.
Current biology : CB26(7)849-61(2016 Apr)
Kevenaar JT,Bianchi S,van Spronsen M,Olieric N,Lipka J,Frias CP,Mikhaylova M,Harterink M,Keijzer N,Wulf PS,Hilbert M,Kapitein LC,de Graaff E,Ahkmanova A,Steinmetz MO,Hoogenraad CC

Homozygous truncating mutation of the KBP gene, encoding a KIF1B-binding protein, in a familial case of fetal polymicrogyria.
Neurogenetics14(3-4)215-24(2013 Nov)
Valence S,Poirier K,Lebrun N,Saillour Y,Sonigo P,Bessi?res B,Atti?-Bitach T,Benachi A,Masson C,Encha-Razavi F,Chelly J,Bahi-Buisson N

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KIFBP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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