Gene Symbol | WIPI2 |
Entrez Gene ID | 26100 |
Full Name | WD repeat domain, phosphoinositide interacting 2 |
Synonyms | ATG18B,Atg21,CGI-50,WIPI-2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]. |
Disorder MIM: |