TMEM98 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM98
Entrez Gene ID	26022
Full Name	transmembrane protein 98
Synonyms	TADA1
General protein information	Preferred Names transmembrane protein 98 Names transmembrane protein 98
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q11.2
Summary	This gene encodes a transmembrane protein. A missense mutation in this gene result in Nanophthalmos 4 (NNO4). Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2014].
Disorder MIM:	615949
Disorder Html:	Nanophthalmos 4, 615972 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_015544.2	NP_056359.2	transmembrane protein 98
NM_001301746.1	NP_001288675.1	transmembrane protein 98
NM_001033504.1	NP_001028676.1	transmembrane protein 98
NM_015544.3	NP_056359.2	transmembrane protein 98

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TMEM98	NP_001039611.1
Homo sapiens (human)	TMEM98	NP_056359.2
Mus musculus (house mouse)	Tmem98	NP_083813.1
Pan troglodytes (chimpanzee)	TMEM98	XP_511405.2
	LOC718166	XP_001110487.2
Canis lupus familiaris (dog)	TMEM98	XP_853351.1
Rattus norvegicus (Norway rat)	Tmem98	NP_001007673.1
Danio rerio (zebrafish)	tmem98	NP_001073664.1
Xenopus tropicalis (tropical clawed frog)	tmem98	NP_001120196.1

Gene Ontology
Bibliography

Related articles in PubMed

The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells.
Fu W, Cheng Y, Zhang Y, Mo X, Li T, Liu Y, Wang P, Pan W, Chen Y, Xue Y, Ma D, Zhang Y, Han W
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research35(9)720-33(2015 Sep)

siRNA-TMEM98 inhibits the invasion and migration of lung cancer cells.
Mao M, Chen J, Li X, Wu Z
International journal of clinical and experimental pathology8(12)15661-9(2015)

Novel TMEM98 mutations in pedigrees with autosomal dominant nanophthalmos.
Khorram D, Choi M, Roos BR, Stone EM, Kopel T, Allen R, Alward WL, Scheetz TE, Fingert JH
Molecular vision211017-23(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

siRNA-TMEM98 inhibited the invasion and migration of non-small cell lung cancer cells.
Title: siRNA-TMEM98 inhibits the invasion and migration of lung cancer cells.

Two novel TMEM98 mutations have been found in two pedigrees with autosomal dominant nanophthalmos.
Title: Novel TMEM98 mutations in pedigrees with autosomal dominant nanophthalmos.

A novel gene associated with nanophthalmos, TMEM98 most likely represents the cause of the disease.
Title: Mutation in TMEM98 in a large white kindred with autosomal dominant nanophthalmos linked to 17p12-q12.

we identified a panel of novel common chemoresistance-associated genes and demonstrated that TMEM98 is a chemoresistance-conferring gene in hepatocellular carcinoma.
Title: Identification of transmembrane protein 98 as a novel chemoresistance-conferring gene in hepatocellular carcinoma.

The following TMEM98 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM98 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12149	NM_015544.3 Latest version!	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12149	NM_001033504.1 Latest version!	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12149	NM_001301746.1 Latest version!	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu12149	NM_015544.2	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM98 ( NM_015544.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056359.2 Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12149
Clone ID Related Accession (Same CDS sequence)	NM_015544.2 , NM_001301746.1 , NM_001033504.1 , NM_015544.3
Accession Version	NM_015544.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	transmembrane protein 98
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC084809.17 and AY358573.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced XM_005257958.1, NM_015544.1. Transcript Variant: This variant (1) represents a predominant transcript. This variant and variants 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AY358573.1, SRR1803613.211851.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056359.2
CDS	459..1139
Translation	METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI

Target ORF information:

RefSeq Version	NM_015544.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015544.2

ORF Insert Sequence:

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM98 ( NM_001301746.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288675.1 Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu12149
Clone ID Related Accession (Same CDS sequence)	NM_015544.2 , NM_001301746.1 , NM_001033504.1 , NM_015544.3
Accession Version	NM_001301746.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	transmembrane protein 98
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC084809.17, BQ228781.1 and AY358573.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BQ228781.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288675.1
CDS	531..1211
Translation	METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI

Target ORF information:

RefSeq Version	NM_001301746.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301746.1

ORF Insert Sequence:

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM98 ( NM_001033504.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001028676.1 Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12149
Clone ID Related Accession (Same CDS sequence)	NM_015544.2 , NM_001301746.1 , NM_001033504.1 , NM_015544.3
Accession Version	NM_001033504.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	transmembrane protein 98
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC084809.17 and AY358573.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.171328.1, SRR1803613.188802.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028676.1
CDS	383..1063
Translation	METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI

Target ORF information:

RefSeq Version	NM_001033504.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033504.1

ORF Insert Sequence:

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM98 ( NM_015544.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056359.2 Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12149
Clone ID Related Accession (Same CDS sequence)	NM_015544.2 , NM_001301746.1 , NM_001033504.1 , NM_015544.3
Accession Version	NM_015544.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	transmembrane protein 98
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC084809.17 and AY358573.1. On Nov 22, 2018 this sequence version replaced NM_015544.2. Transcript Variant: This variant (1) represents a predominant transcript. This variant and variants 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.149046.1, SRR1803616.21277.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000579849.6/ ENSP00000463245.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056359.2
CDS	216..896
Translation	METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI

Target ORF information:

RefSeq Version	NM_015544.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 98 (TMEM98), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015544.3

ORF Insert Sequence:

ATGGAGACTG TGGTGATTGT TGCCATAGGT GTGCTGGCCA CCATCTTTCT GGCTTCGTTT 
GCAGCCTTGG TGCTGGTTTG CAGGCAGCGC TACTGCCGGC CGCGAGACCT GCTGCAGCGC 
TATGATTCTA AGCCCATTGT GGACCTCATT GGTGCCATGG AGACCCAGTC TGAGCCCTCT 
GAGTTAGAAC TGGACGATGT CGTTATCACC AACCCCCACA TTGAGGCCAT TCTGGAGAAT 
GAAGACTGGA TCGAAGATGC CTCGGGTCTC ATGTCCCACT GCATTGCCAT CTTGAAGATT 
TGTCACACTC TGACAGAGAA GCTTGTTGCC ATGACAATGG GCTCTGGGGC CAAGATGAAG 
ACTTCAGCCA GTGTCAGCGA CATCATTGTG GTGGCCAAGC GGATCAGCCC CAGGGTGGAT 
GATGTTGTGA AGTCGATGTA CCCTCCGTTG GACCCCAAAC TCCTGGACGC ACGGACGACT 
GCCCTGCTCC TGTCTGTCAG TCACCTGGTG CTGGTGACAA GGAATGCCTG CCATCTGACG 
GGAGGCCTGG ACTGGATTGA CCAGTCTCTG TCGGCTGCTG AGGAGCATTT GGAAGTCCTT 
CGAGAAGCAG CCCTAGCTTC TGAGCCAGAT AAAGGCCTCC CAGGCCCTGA AGGCTTCCTG 
CAGGAGCAGT CTGCAATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research35(9)720-33(2015 Sep)
Fu W,Cheng Y,Zhang Y,Mo X,Li T,Liu Y,Wang P,Pan W,Chen Y,Xue Y,Ma D,Zhang Y,Han W

siRNA-TMEM98 inhibits the invasion and migration of lung cancer cells.
International journal of clinical and experimental pathology8(12)15661-9(2015)
Mao M,Chen J,Li X,Wu Z

Novel TMEM98 mutations in pedigrees with autosomal dominant nanophthalmos.
Molecular vision211017-23(2015)
Khorram D,Choi M,Roos BR,Stone EM,Kopel T,Allen R,Alward WL,Scheetz TE,Fingert JH

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

TMEM98 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報