FAM32A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FAM32A
Entrez Gene ID	26017
Full Name	family with sequence similarity 32 member A
Synonyms	OTAG-12,OTAG12
General protein information	Preferred Names family with sequence similarity 32 member A Names protein FAM32A ovarian tumor associated gene-12
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.11
Disorder MIM:	614554

mRNA and Protein(s)

mRNA	Protein	Name
NM_014077.3	NP_054796.1	protein FAM32A
NM_014077.4	NP_054796.1	protein FAM32A
XM_011527898.1	XP_011526200.1	protein FAM32A isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	FAM32A	NP_054796.1
Mus musculus (house mouse)	Fam32a	NP_080731.1
Gallus gallus (chicken)	FAM32A	XP_418266.2
Pan troglodytes (chimpanzee)	FAM32A	XP_512465.2
Canis lupus familiaris (dog)	FAM32A	XP_005632807.1
Bos taurus (cattle)	FAM32A	NP_001098474.1
Rattus norvegicus (Norway rat)	Fam32a	NP_001121550.1
Danio rerio (zebrafish)	fam32a	NP_001002203.1
Xenopus tropicalis (tropical clawed frog)	fam32a	NP_001120136.1

Gene Ontology
Bibliography

Related articles in PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Dynamic protein-protein interaction wiring of the human spliceosome.
Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, L?hrmann R, Stelzl U
Molecular cell45(4)567-80(2012 Feb)

Anti-proliferative and pro-apoptotic actions of a novel human and mouse ovarian tumor-associated gene OTAG-12: downregulation, alternative splicing and drug sensitization.
Chen X, Zhang H, Aravindakshan JP, Gotlieb WH, Sairam MR
Oncogene30(25)2874-87(2011 Jun)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

study showed that hOTAG-12b increases mRNAs of pro-apoptotic genes such as BAD, GADD45alpha and CIEDB, while inhibiting anti-apoptotic NAIP and Akt1 expression, suggesting that hOTAG-12b-induced apoptosis might be p53-independent
Title: Anti-proliferative and pro-apoptotic actions of a novel human and mouse ovarian tumor-associated gene OTAG-12: downregulation, alternative splicing and drug sensitization.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following FAM32A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAM32A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30948	NM_014077.4 Latest version!	Homo sapiens family with sequence similarity 32 member A (FAM32A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu66719	XM_011527898.1 Latest version!	Homo sapiens family with sequence similarity 32 member A (FAM32A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu30948	NM_014077.3	Homo sapiens family with sequence similarity 32 member A (FAM32A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FAM32A ( NM_014077.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_054796.1 Homo sapiens family with sequence similarity 32 member A (FAM32A), mRNA.

Price & Availability↑

CloneID	OHu30948
Clone ID Related Accession (Same CDS sequence)	NM_014077.3 , NM_014077.4
Accession Version	NM_014077.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 339bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	protein FAM32A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG749750.1 and BC000639.1. On Jan 17, 2015 this sequence version replaced NM_014077.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.363081.1, SRR1163657.551447.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGCCT ACGAGCAGGT CCAAAAGGGA CCCCTGAAGC TGAAAGGCGT CGCAGAGCTG 
GGAGTGACCA AGCGGAAGAA GAAAAAGAAG GACAAAGACA AAGCGAAACT CCTGGAAGCA 
ATGGGAACGA GCAAAAAGAA CGAGGAGGAG AAGCGGCGCG GCCTGGACAA GCGGACCCCG 
GCCCAGGCGG CCTTCGAGAA AATGCAGGAG AAGCGGCAAA TGGAAAGGAT CCTAAAGAAG 
GCATCCAAAA CCCACAAGCA GAGAGTGGAG GACTTCAACA GACACCTGGA CACACTCACG 
GAGCATTACG ACATTCCCAA AGTCAGCTGG ACGAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_054796.1
CDS	43..381
Translation	MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKLLEAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK

Target ORF information:

RefSeq Version	NM_014077.3
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 32 member A (FAM32A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014077.3

ORF Insert Sequence:

ATGGAGGCCT ACGAGCAGGT CCAAAAGGGA CCCCTGAAGC TGAAAGGCGT CGCAGAGCTG 
GGAGTGACCA AGCGGAAGAA GAAAAAGAAG GACAAAGACA AAGCGAAACT CCTGGAAGCA 
ATGGGAACGA GCAAAAAGAA CGAGGAGGAG AAGCGGCGCG GCCTGGACAA GCGGACCCCG 
GCCCAGGCGG CCTTCGAGAA AATGCAGGAG AAGCGGCAAA TGGAAAGGAT CCTAAAGAAG 
GCATCCAAAA CCCACAAGCA GAGAGTGGAG GACTTCAACA GACACCTGGA CACACTCACG 
GAGCATTACG ACATTCCCAA AGTCAGCTGG ACGAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM32A ( NM_014077.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_054796.1 Homo sapiens family with sequence similarity 32 member A (FAM32A), mRNA.

Price & Availability↑

CloneID	OHu30948
Clone ID Related Accession (Same CDS sequence)	NM_014077.3 , NM_014077.4
Accession Version	NM_014077.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 339bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	protein FAM32A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG749750.1 and BC000639.1. On Nov 23, 2018 this sequence version replaced NM_014077.3. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1019033.1, SRR3476690.541569.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263384.12/ ENSP00000263384.6 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGCCT ACGAGCAGGT CCAAAAGGGA CCCCTGAAGC TGAAAGGCGT CGCAGAGCTG 
GGAGTGACCA AGCGGAAGAA GAAAAAGAAG GACAAAGACA AAGCGAAACT CCTGGAAGCA 
ATGGGAACGA GCAAAAAGAA CGAGGAGGAG AAGCGGCGCG GCCTGGACAA GCGGACCCCG 
GCCCAGGCGG CCTTCGAGAA AATGCAGGAG AAGCGGCAAA TGGAAAGGAT CCTAAAGAAG 
GCATCCAAAA CCCACAAGCA GAGAGTGGAG GACTTCAACA GACACCTGGA CACACTCACG 
GAGCATTACG ACATTCCCAA AGTCAGCTGG ACGAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_054796.1
CDS	34..372
Translation	MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKLLEAMGTSKKNEEEKRRGLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEHYDIPKVSWTK

Target ORF information:

RefSeq Version	NM_014077.4
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 32 member A (FAM32A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014077.4

ORF Insert Sequence:

ATGGAGGCCT ACGAGCAGGT CCAAAAGGGA CCCCTGAAGC TGAAAGGCGT CGCAGAGCTG 
GGAGTGACCA AGCGGAAGAA GAAAAAGAAG GACAAAGACA AAGCGAAACT CCTGGAAGCA 
ATGGGAACGA GCAAAAAGAA CGAGGAGGAG AAGCGGCGCG GCCTGGACAA GCGGACCCCG 
GCCCAGGCGG CCTTCGAGAA AATGCAGGAG AAGCGGCAAA TGGAAAGGAT CCTAAAGAAG 
GCATCCAAAA CCCACAAGCA GAGAGTGGAG GACTTCAACA GACACCTGGA CACACTCACG 
GAGCATTACG ACATTCCCAA AGTCAGCTGG ACGAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FAM32A ( XM_011527898.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526200.1 Homo sapiens family with sequence similarity 32 member A (FAM32A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu66719
Clone ID Related Accession (Same CDS sequence)	XM_011527898.1
Accession Version	XM_011527898.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein FAM32A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGACC GGAAGTGGGC GCCAAATTCG GAAGTGTGGC AGCAGATAGG AATCGAAGGG 
CACTCATTCG CTTGGCTCTC TGTCCCGCCC ACTACCCGGA AGTGTGGCCC GGGTCCAGAA 
CCAAGAGCGC ATGCTCACCT TGTAGCTCAG CCAATCAAAG AGAAGCGAGG CGGCCATTCG 
GGCGGAAATA GTGTTTGCAA ACAGGAAGTG TGGCACTCCA GCTACCGAAG CACTGGAGAG 
TGTCATGGAG GCCTACGAGC AGGTCCAAAA GGGACCCCTG AAGCTGAAAG GCGTCGCAGA 
GCTGGGAGTG ACCAAGCGGA AGAAGAAAAA GAAGGACAAA GACAAAGCGA AACTCCTGGA 
AGCAATGGGA ACGAGCAAAA AGAACGAGGA GGAGAAGCGG CGCGGCCTGG ACAAGCGGAC 
CCCGGCCCAG GCGGCCTTCG AGAAAATGCA GGAGAAGCGG GACTTCAACA GACACCTGGA 
CACACTCACG GAGCATTACG ACATTCCCAA AGTCAGCTGG ACGAAGTAGC CGCCTGCCCC 
CAGTATGGAG CAGCATCGAG GGTTCGCAAA AGGCCACACT GGGGTTGTGT GTGTTTCCTT 
TGGTATATTC TGGAAACATG GCTACACACA CCCTTGCATC TTCTGCTACA GACTGCTTTT 
CGAAGCTGTG TACCCTCATT CTGGAACTTG ATTAAAGTAA GATCGTCCTT GTACTCAGTT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526200.1
CDS	16..738
Translation	MGDRKWAPNSEVWQQIGIEGHSFAWLSVPPTTRKCGPGPEPRAHAHLVAQPIKEKRGGHSGGNSVCKQEVWHSSYRSTGECHGGLRAGPKGTPEAERRRRAGSDQAEEEKEGQRQSETPGSNGNEQKERGGEAARPGQADPGPGGLRENAGEAGLQQTPGHTHGALRHSQSQLDEVAACPQYGAASRVRKRPHWGCVCFLWYILETWLHTPLHLLLQTAFRSCVPSFWNLIKVRSSLYSV

Target ORF information:

RefSeq Version	XM_011527898.1
Organism	Homo sapiens(human)
Definition	Homo sapiens family with sequence similarity 32 member A (FAM32A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527898.1

ORF Insert Sequence:

ATGGGAGACC GGAAGTGGGC GCCAAATTCG GAAGTGTGGC AGCAGATAGG AATCGAAGGG 
CACTCATTCG CTTGGCTCTC TGTCCCGCCC ACTACCCGGA AGTGTGGCCC GGGTCCAGAA 
CCAAGAGCGC ATGCTCACCT TGTAGCTCAG CCAATCAAAG AGAAGCGAGG CGGCCATTCG 
GGCGGAAATA GTGTTTGCAA ACAGGAAGTG TGGCACTCCA GCTACCGAAG CACTGGAGAG 
TGTCATGGAG GCCTACGAGC AGGTCCAAAA GGGACCCCTG AAGCTGAAAG GCGTCGCAGA 
GCTGGGAGTG ACCAAGCGGA AGAAGAAAAA GAAGGACAAA GACAAAGCGA AACTCCTGGA 
AGCAATGGGA ACGAGCAAAA AGAACGAGGA GGAGAAGCGG CGCGGCCTGG ACAAGCGGAC 
CCCGGCCCAG GCGGCCTTCG AGAAAATGCA GGAGAAGCGG GACTTCAACA GACACCTGGA 
CACACTCACG GAGCATTACG ACATTCCCAA AGTCAGCTGG ACGAAGTAGC CGCCTGCCCC 
CAGTATGGAG CAGCATCGAG GGTTCGCAAA AGGCCACACT GGGGTTGTGT GTGTTTCCTT 
TGGTATATTC TGGAAACATG GCTACACACA CCCTTGCATC TTCTGCTACA GACTGCTTTT 
CGAAGCTGTG TACCCTCATT CTGGAACTTG ATTAAAGTAA GATCGTCCTT GTACTCAGTT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Dynamic protein-protein interaction wiring of the human spliceosome.
Molecular cell45(4)567-80(2012 Feb)
Hegele A,Kamburov A,Grossmann A,Sourlis C,Wowro S,Weimann M,Will CL,Pena V,L?hrmann R,Stelzl U

Anti-proliferative and pro-apoptotic actions of a novel human and mouse ovarian tumor-associated gene OTAG-12: downregulation, alternative splicing and drug sensitization.
Oncogene30(25)2874-87(2011 Jun)
Chen X,Zhang H,Aravindakshan JP,Gotlieb WH,Sairam MR

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

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FAM32A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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