TIPARP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TIPARP
Entrez Gene ID	25976
Full Name	TCDD inducible poly(ADP-ribose) polymerase
Synonyms	ARTD14,PARP7,pART14
General protein information	Preferred Names TCDD inducible poly(ADP-ribose) polymerase Names TCDD-inducible poly [ADP-ribose] polymerase ADP-ribosyltransferase diphtheria toxin-like 14 poly [ADP-ribose] polymerase 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q25.31
Summary	This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
Disorder MIM:	612480

mRNA and Protein(s)

mRNA	Protein	Name
NM_015508.4	NP_056323.2	TCDD-inducible poly [ADP-ribose] polymerase
XM_011512668.1	XP_011510970.1	TCDD-inducible poly [ADP-ribose] polymerase isoform X1
NM_001184717.1	NP_001171646.1	protein mono-ADP-ribosyltransferase TIPARP
NM_015508.5	NP_056323.2	protein mono-ADP-ribosyltransferase TIPARP
NM_001184718.1	NP_001171647.1	protein mono-ADP-ribosyltransferase TIPARP

Pathways from BioSystems

Homologies

Homo sapiens (human)	TIPARP	NP_001171646.1
Rattus norvegicus (Norway rat)	Tiparp	XP_003749342.1
Pan troglodytes (chimpanzee)	TIPARP	XP_001150766.1
Danio rerio (zebrafish)	tiparp	NP_001038484.1
Xenopus tropicalis (tropical clawed frog)	tiparp	NP_001106413.1
	TIPARP	XP_001104362.1
Canis lupus familiaris (dog)	TIPARP	XP_854837.2
Bos taurus (cattle)	TIPARP	NP_001192977.1
Mus musculus (house mouse)	Tiparp	NP_849223.2
Gallus gallus (chicken)	TIPARP	XP_422828.1

Gene Ontology
Bibliography

Related articles in PubMed

The aryl hydrocarbon receptor regulates the expression of TIPARP and its cis long non-coding RNA, TIPARP-AS1.
Grimaldi G, Rajendra S, Matthews J
Biochemical and biophysical research communications495(3)2356-2362(2018 Jan)

Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response.
Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T
Proceedings of the National Academy of Sciences of the United States of America114(10)2681-2686(2017 Mar)

TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors.
Bindesb?ll C, Tan S, Bott D, Cho T, Tamblyn L, MacPherson L, Gr?nning-Wang L, Nebb HI, Matthews J
The Biochemical journal473(7)899-910(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these data identify a new mechanism of LXR regulation that involves TIPARP, ADP-ribosylation and MACROD1.
Title: TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors.

Knockdown of TiPARP, but not AHRR, increased 2,3,7,8-tetrachlorodibenzo-p-dioxin - induced CYP1A1 mRNA and AHR protein levels.
Title: Aryl hydrocarbon receptor repressor and TiPARP (ARTD14) use similar, but also distinct mechanisms to repress aryl hydrocarbon receptor signaling.

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

TIPARP (DKFZp434J214) gene is amplified in HNSCC. TIPARP, FLJ22693 and ZAP proteins with TPH, WW and PARP-like domains constitute the TIPARP family.
Title: Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31.

The following TIPARP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TIPARP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00791	NM_015508.5 Latest version!	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu00791	NM_001184718.1 Latest version!	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu00791	NM_001184717.1 Latest version!	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu00791	XM_011512668.1 Latest version!	Homo sapiens TCDD-inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu00791	NM_015508.4	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TIPARP ( NM_015508.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056323.2 Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00791
Clone ID Related Accession (Same CDS sequence)	NM_015508.4 , XM_011512668.1 , NM_001184717.1 , NM_015508.5 , NM_001184718.1
Accession Version	NM_015508.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	TCDD-inducible poly [ADP-ribose] polymerase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB033700.1, BX537965.1, AC092927.5 and BC050350.1. On May 15, 2010 this sequence version replaced NM_015508.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.73394.1, SRR1660805.227270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056323.2
CDS	423..2396
Translation	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	NM_015508.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015508.4

ORF Insert Sequence:

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIPARP ( NM_001184717.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171646.1 Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00791
Clone ID Related Accession (Same CDS sequence)	NM_015508.4 , XM_011512668.1 , NM_001184717.1 , NM_015508.5 , NM_001184718.1
Accession Version	NM_001184717.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	protein mono-ADP-ribosyltransferase TIPARP
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC092927.5, BX537965.1 and BC050350.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR749647.1, SRR1803611.179132.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2146982 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171646.1
CDS	508..2481
Translation	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	NM_001184717.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184717.1

ORF Insert Sequence:

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIPARP ( NM_015508.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056323.2 Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00791
Clone ID Related Accession (Same CDS sequence)	NM_015508.4 , XM_011512668.1 , NM_001184717.1 , NM_015508.5 , NM_001184718.1
Accession Version	NM_015508.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	protein mono-ADP-ribosyltransferase TIPARP
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX537965.1, AC092927.5 and BC050350.1. On Nov 23, 2018 this sequence version replaced NM_015508.4. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.73394.1, SRR1660803.174701.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000295924.12/ ENSP00000295924.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056323.2
CDS	249..2222
Translation	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	NM_015508.5
Organism	Homo sapiens(human)
Definition	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015508.5

ORF Insert Sequence:

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIPARP ( NM_001184718.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171647.1 Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00791
Clone ID Related Accession (Same CDS sequence)	NM_015508.4 , XM_011512668.1 , NM_001184717.1 , NM_015508.5 , NM_001184718.1
Accession Version	NM_001184718.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	protein mono-ADP-ribosyltransferase TIPARP
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC034397.1, AC092927.5, BX537965.1 and BC050350.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC034397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171647.1
CDS	73..2046
Translation	MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	NM_001184718.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TCDD inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184718.1

ORF Insert Sequence:

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TIPARP ( XM_011512668.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510970.1 Homo sapiens TCDD-inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu00791
Clone ID Related Accession (Same CDS sequence)	NM_015508.4 , XM_011512668.1 , NM_001184717.1 , NM_015508.5 , NM_001184718.1
Accession Version	XM_011512668.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	TCDD-inducible poly [ADP-ribose] polymerase isoform X1
Comment

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011510970.1

Translation

MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI

Target ORF information:

RefSeq Version	XM_011512668.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens TCDD-inducible poly(ADP-ribose) polymerase (TIPARP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512668.1

ORF Insert Sequence:

ATGGAAATGG AAACCACCGA ACCTGAGCCA GACTGTGTAG TGCAGCCTCC CTCTCCTCCT 
GATGACTTTT CATGCCAAAT GAGACTCTCT GAGAAGATCA CTCCATTGAA GACTTGTTTT 
AAGAAAAAGG ATCAGAAAAG ATTGGGAACT GGAACCCTGA GGTCTTTGAG GCCAATATTA 
AACACTCTTC TAGAATCTGG CTCACTTGAT GGGGTTTTTA GATCTAGGAA CCAGAGTACA 
GATGAGAACA GCTTACATGA ACCTATGATG AAGAAAGCCA TGGAAATCAA TTCATCATGC 
CCACCAGCAG AAAATAATAT GTCTGTTCTG ATTCCTGATA GGACAAATGT TGGGGACCAG 
ATACCGGAAG CCCATCCTTC CACTGAAGCT CCAGAACGAG TGGTTCCAAT CCAAGATCAC 
AGCTTTCCAT CAGAAACCCT CAGTGGGACG GTGGCAGATT CCACACCAGC TCACTTCCAG 
ACTGATCTTT TGCACCCAGT TTCAAGTGAT GTTCCTACTA GTCCTGACTG CTTAGACAAA 
GTCATAGATT ATGTTCCAGG CATTTTCCAA GAAAACAGTT TTACAATCCA ATACATTCTG 
GACACCAGTG ATAAGCTGAG TACTGAGCTC TTTCAGGACA AAAGTGAAGA GGCTTCCCTT 
GACCTCGTGT TTGAGCTGGT GAACCAGTTG CAGTACCACA CTCACCAAGA GAACGGAATT 
GAAATTTGCA TGGACTTTCT GCAAGGCACT TGTATTTATG GCAGGGATTG TTTGAAGCAC 
CACACTGTCT TGCCATATCA TTGGCAGATC AAAAGGACAA CTACTCAAAA GTGGCAGAGT 
GTATTCAATG ATTCTCAGGA GCACTTGGAA AGATTTTACT GTAACCCAGA AAATGATAGA 
ATGAGAATGA AGTATGGAGG ACAAGAATTT TGGGCAGATT TGAATGCCAT GAACGTGTAT 
GAAACAACTG AATTTGACCA ACTACGAAGG CTGTCCACAC CACCCTCTAG CAATGTCAAC 
TCTATTTACC ACACAGTCTG GAAATTCTTC TGTAGGGACC ACTTTGGATG GAGAGAGTAT 
CCCGAGTCTG TCATTCGATT GATTGAAGAA GCCAACTCTC GGGGTCTGAA AGAGGTTCGA 
TTTATGATGT GGAATAACCA CTACATCCTC CACAATTCAT TCTTCAGGAG AGAGATAAAA 
AGGAGACCCC TCTTCCGCTC CTGTTTTATA CTGCTTCCAT ATTTACAGAC ACTTGGTGGG 
GTTCCCACAC AAGCTCCTCC ACCTCTTGAA GCAACTTCAT CATCACAAAT TATCTGCCCA 
GATGGGGTCA CTTCAGCAAA CTTTTACCCT GAAACTTGGG TTTATATGCA TCCATCTCAG 
GACTTCATCC AAGTCCCTGT TTCTGCAGAG GATAAAAGTT ATCGGATCAT TTACAATCTT 
TTTCATAAGA CTGTGCCTGA GTTTAAATAC AGAATTTTGC AGATATTGAG AGTCCAAAAC 
CAGTTTCTTT GGGAGAAATA TAAAAGGAAA AAGGAATATA TGAACAGGAA AATGTTTGGC 
CGTGACAGGA TAATAAATGA GAGACATTTA TTTCATGGAA CATCCCAGGA TGTGGTAGAT 
GGAATCTGCA AACACAACTT TGACCCTCGA GTCTGTGGAA AGCATGCTAC AATGTTTGGA 
CAAGGCAGTT ATTTTGCAAA GAAGGCAAGC TACTCTCATA ACTTTTCTAA GAAGTCCTCC 
AAAGGAGTCC ACTTCATGTT TCTGGCCAAA GTGCTGACGG GCAGATACAC AATGGGCAGT 
CATGGCATGA GAAGGCCCCC GCCAGTCAAT CCTGGCAGTG TCACCAGTGA CCTTTATGAC 
TCTTGTGTGG ATAATTTCTT TGAGCCTCAG ATTTTTGTCA TTTTTAATGA TGACCAGAGT 
TACCCTTATT TTGTTATCCA ATATGAAGAA GTCAGTAACA CTGTTTCCAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The aryl hydrocarbon receptor regulates the expression of TIPARP and its cis long non-coding RNA, TIPARP-AS1.
Biochemical and biophysical research communications495(3)2356-2362(2018 Jan)
Grimaldi G,Rajendra S,Matthews J

Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response.
Proceedings of the National Academy of Sciences of the United States of America114(10)2681-2686(2017 Mar)
Kozaki T,Komano J,Kanbayashi D,Takahama M,Misawa T,Satoh T,Takeuchi O,Kawai T,Shimizu S,Matsuura Y,Akira S,Saitoh T

TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors.
The Biochemical journal473(7)899-910(2016 Apr)
Bindesb?ll C,Tan S,Bott D,Cho T,Tamblyn L,MacPherson L,Gr?nning-Wang L,Nebb HI,Matthews J

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TIPARP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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