Gene Symbol | NECTIN3 |
Entrez Gene ID | 25945 |
Full Name | nectin cell adhesion molecule 3 |
Synonyms | CD113,CDW113,NECTIN-3,PPR3,PRR3,PVRL3,PVRR3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]. |
Disorder MIM: |