Gene Symbol | NCR3 |
Entrez Gene ID | 259197 |
Full Name | natural cytotoxicity triggering receptor 3 |
Synonyms | 1C7,CD337,LY117,MALS,NKp30 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(Human) |
Genome | |
Summary | The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]. |
Disorder MIM: | |
Disorder Html: | {Malaria, mild, susceptibility to}, 609148 (3) |