Gene Symbol | RCHY1 |
Entrez Gene ID | 25898 |
Full Name | ring finger and CHY zinc finger domain containing 1 |
Synonyms | ARNIP,CHIMP,PIRH2,PRO1996,RNF199,ZCHY,ZNF363 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]. |
Disorder MIM: |