COG4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	COG4
Entrez Gene ID	25839
Full Name	component of oligomeric golgi complex 4
Synonyms	CDG2J,COD1
General protein information	Preferred Names component of oligomeric golgi complex 4 Names conserved oligomeric Golgi complex subunit 4 COG complex subunit 4 complexed with Dor1p conserved oligomeric Golgi complex protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Summary	The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010].
Disorder MIM:	606976
Disorder Html:	Congenital disorder of glycosylation, type IIj, 613489 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011522981.2	XP_011521283.1	conserved oligomeric Golgi complex subunit 4 isoform X1
NM_015386.2	NP_056201.2	conserved oligomeric Golgi complex subunit 4 isoform 1
NM_001195139.2	NP_001182068.2	conserved oligomeric Golgi complex subunit 4 isoform 2
NM_015386.3	NP_056201.2	conserved oligomeric Golgi complex subunit 4 isoform 1
NM_001195139.1	NP_001182068.1	conserved oligomeric Golgi complex subunit 4 isoform 2
NM_001365426.1	NP_001352355.1	conserved oligomeric Golgi complex subunit 4 isoform 3
XM_011522981.3	XP_011521283.1	conserved oligomeric Golgi complex subunit 4 isoform X1
XM_024450224.1	XP_024305992.1	conserved oligomeric Golgi complex subunit 4 isoform X2

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008875	XP_552742.3
Bos taurus (cattle)	COG4	NP_001029755.1
Mus musculus (house mouse)	Cog4	NP_598734.1
Gallus gallus (chicken)	COG4	NP_001012793.1
Danio rerio (zebrafish)	cog4	NP_001034912.1
Oryza sativa (rice)	Os02g0456000	NP_001172943.1
Xenopus tropicalis (tropical clawed frog)	LOC100145689	NP_001120535.1
Canis lupus familiaris (dog)	COG4	XP_546836.1
Homo sapiens (human)	COG4	NP_056201.2
Pan troglodytes (chimpanzee)	COG4	XP_511080.3
	COG4	XP_002808350.1
Rattus norvegicus (Norway rat)	Cog4	NP_001101919.1
Drosophila melanogaster (fruit fly)	CG7456	NP_609413.1
Caenorhabditis elegans (roundworm)	cogc-4	NP_493966.1
Arabidopsis thaliana (thale cress)	AT4G01400	NP_001154198.1

Gene Ontology
Bibliography

Related articles in PubMed

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, T?ernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Zhao JH, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Coll?e JM, Couch FJ, Couper D, Coveillo AD, Cox A, Czene K, D'adamo AP, Smith GD, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, Garc?a-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Gu?nel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, M?gi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylk?s K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, St?ckl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, V?lzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, , , , , , , Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, J?rvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, S?rensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK
Nature514(7520)92-97(2014 Oct)

Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.
Richardson BC, Smith RD, Ungar D, Nakamura A, Jeffrey PD, Lupashin VV, Hughson FM
Proceedings of the National Academy of Sciences of the United States of America106(32)13329-34(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A novel R729W missense mutation in COG4 was associated with the congenital disorder of glycosylation type II.
Title: Golgi function and dysfunction in the first COG4-deficient CDG type II patient.

The 1.9 A crystal structure of a Cog4 C-terminal fragment, was determined. Arg 729 is found to occupy a key position at the center of a salt bridge network, thereby stabilizing Cog4's small C-terminal domain.
Title: Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.

Study shows that the SM protein, Sly1, interacts directly with the conserved oligomeric Golgi (COG) tethering complex; Sly1-COG interaction is mediated by the Cog4 subunit, which also interacts with Syntaxin 5 through a different binding site.
Title: Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing.

The following COG4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COG4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu49333	NM_001365426.1 Latest version!	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu49333	XM_011522981.3 Latest version!	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu104123	XM_024450224.1 Latest version!	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu16785	NM_001195139.1 Latest version!	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu17980	NM_015386.3 Latest version!	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu107929	NM_001195139.2 Latest version!	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu17980	NM_015386.2	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu49333	XM_011522981.2	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

COG4 ( NM_001365426.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001352355.1 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu49333
Clone ID Related Accession (Same CDS sequence)	XM_011522981.2 , NM_001365426.1 , XM_011522981.3
Accession Version	NM_001365426.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106804.4. On Jan 26, 2019 this sequence version replaced XM_011522981.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.103057.1, SRR1803614.239512.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGGAG TTCAGACTGC TTTGAGGAGT GAAGATTATG AGCAGGCTGC AGCACATACT 
CATCGCTACT TGTGCCTGGA CAAGTCGGTC ATTGAGCTCA GCCGACAGGG CAAAGAGGGG 
AGCATGATTG ATGCCAACCT GAAATTGCTG CAGGAAGCTG AGCAACGTCT CAAAGCCATT 
GTGGCAGAGA AGTTTGCCAT TGCCACCAAG GAAGGTGATC TGCCCCAGGT GGAGCGCTTC 
TTCAAGATCT TCCCACTGCT GGGTTTGCAT GAGGAGGGAT TAAGAAAGTT CTCGGAGTAC 
CTTTGCAAGC AGGTGGCCAG TAAAGCTGAG GAGAATCTGC TCATGGTGCT GGGGACAGAC 
ATGAGTGATC GGAGAGCTGC AGTCATCTTT GCAGATACAC TTACTCTTCT GTTTGAAGGG 
ATTGCCCGCA TTGTGGAGAC CCACCAGCCA ATAGTGGAGA CCTATTATGG GCCAGGGAGA 
CTCTATACCC TGATCAAATA TCTGCAGGTG GAATGTGACA GACAGGTGGA GAAGGTGGTA 
GACAAGTTCA TCAAGCAAAG GGACTACCAC CAGCAGTTCC GGCATGTTCA GAACAACCTG 
ATGAGAAATT CTACAACAGA AAAAATCGAA CCAAGAGAAC TGGACCCCAT CCTGACTGAG 
GTCACCCTGA TGAATGCCCG CAGTGAGCTA TACTTACGCT TCCTCAAGAA GAGGATTAGC 
TCTGATTTTG AGGTGGGAGA CTCCATGGCC TCAGAGGAAG TAAAGCAAGA GCACCAGAAG 
TGTCTGGACA AACTCCTCAA TAACTGCCTT TTGAGCTGTA CCATGCAGGA GCTAATTGGC 
TTATATGTTA CCATGGAGGA GTACTTCATG AGGGAGACTG TCAATAAGGC TGTGGCTCTG 
GACACCTATG AGAAGGGCCA GCTGACATCC AGCATGGTGG ATGATGTCTT CTACATTGTT 
AAGAAGTGCA TTGGGCGGGC TCTGTCCAGC TCCAGCATTG ACTGTCTCTG TGCCATGATC 
AACCTCGCCA CCACAGAGCT GGAGTCTGAC TTCAGGGATG TTCTGTGTAA TAAGCTGCGG 
ATGGGCTTTC CTGCCACCAC CTTCCAGGAC ATCCAGCGCG GGGTGACAAG TGCCGTGAAC 
ATCATGCACA GCAGCCTCCA GCAAGGCAAA TTTGACACAA AAGGCATCGA GAGTACTGAC 
GAGGCGAAGA TGTCCTTCCT GGTGACTCTG AACAACGTGG AAGTCTGCAG TGAAAACATC 
TCCACTCTGA AGAAGACACT GGAGAGTGAC TGCACCAAGC TCTTCAGCCA GGGCATTGGA 
GGGGAGCAGG CCCAGGCCAA GTTTGACAGC TGCCTTTCTG ACTTGGCCGC CGTGTCCAAC 
AAATTCCGAG ACCTCTTGCA GGAAGGGCTG ACGGAGCTCA ACAGCACAGC CATCAAGCCA 
CAGGTGCAGC CTTGGATCAA CAGCTTTTTC TCCGTCTCCC ACAACATCGA GGAGGAAGAA 
TTCAATGACT ATGAGGCCAA CGACCCTTGG GTACAACAGT TCATCCTTAA CCTGGAGCAG 
CAAATGGCAG AGTTCAAGGC CAGCCTGTCC CCGGTCATCT ACGACAGCCT AACCGGCCTC 
ATGACTAGCC TTGTTGCCGT CGAGTTGGAG AAAGTGGTGC TGAAATCCAC CTTTAACCGG 
CTGGGTGGTC TGCAGTTTGA CAAGGAGCTG AGGTCGCTCA TTGCCTACCT TACCACGGTG 
ACCACCTGGA CCATCCGAGA CAAGTTTGCC CGGCTCTCCC AGATGGCCAC CATCCTCAAT 
CTGGAGCGGG TGACCGAGAT CCTCGATTAC TGGGGACCCA ATTCCGGCCC ATTGACGTGG 
CGCCTCACCC CTGCTGAAGT GCGCCAGGTG CTGGCCCTGC GGATAGACTT CCGCAGTGAA 
GATATCAAGA GGCTGCGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001352355.1
CDS	611..2554
Translation	MDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	NM_001365426.1
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001365426.1

ORF Insert Sequence:

ATGGATGGAG TTCAGACTGC TTTGAGGAGT GAAGATTATG AGCAGGCTGC AGCACATACT 
CATCGCTACT TGTGCCTGGA CAAGTCGGTC ATTGAGCTCA GCCGACAGGG CAAAGAGGGG 
AGCATGATTG ATGCCAACCT GAAATTGCTG CAGGAAGCTG AGCAACGTCT CAAAGCCATT 
GTGGCAGAGA AGTTTGCCAT TGCCACCAAG GAAGGTGATC TGCCCCAGGT GGAGCGCTTC 
TTCAAGATCT TCCCACTGCT GGGTTTGCAT GAGGAGGGAT TAAGAAAGTT CTCGGAGTAC 
CTTTGCAAGC AGGTGGCCAG TAAAGCTGAG GAGAATCTGC TCATGGTGCT GGGGACAGAC 
ATGAGTGATC GGAGAGCTGC AGTCATCTTT GCAGATACAC TTACTCTTCT GTTTGAAGGG 
ATTGCCCGCA TTGTGGAGAC CCACCAGCCA ATAGTGGAGA CCTATTATGG GCCAGGGAGA 
CTCTATACCC TGATCAAATA TCTGCAGGTG GAATGTGACA GACAGGTGGA GAAGGTGGTA 
GACAAGTTCA TCAAGCAAAG GGACTACCAC CAGCAGTTCC GGCATGTTCA GAACAACCTG 
ATGAGAAATT CTACAACAGA AAAAATCGAA CCAAGAGAAC TGGACCCCAT CCTGACTGAG 
GTCACCCTGA TGAATGCCCG CAGTGAGCTA TACTTACGCT TCCTCAAGAA GAGGATTAGC 
TCTGATTTTG AGGTGGGAGA CTCCATGGCC TCAGAGGAAG TAAAGCAAGA GCACCAGAAG 
TGTCTGGACA AACTCCTCAA TAACTGCCTT TTGAGCTGTA CCATGCAGGA GCTAATTGGC 
TTATATGTTA CCATGGAGGA GTACTTCATG AGGGAGACTG TCAATAAGGC TGTGGCTCTG 
GACACCTATG AGAAGGGCCA GCTGACATCC AGCATGGTGG ATGATGTCTT CTACATTGTT 
AAGAAGTGCA TTGGGCGGGC TCTGTCCAGC TCCAGCATTG ACTGTCTCTG TGCCATGATC 
AACCTCGCCA CCACAGAGCT GGAGTCTGAC TTCAGGGATG TTCTGTGTAA TAAGCTGCGG 
ATGGGCTTTC CTGCCACCAC CTTCCAGGAC ATCCAGCGCG GGGTGACAAG TGCCGTGAAC 
ATCATGCACA GCAGCCTCCA GCAAGGCAAA TTTGACACAA AAGGCATCGA GAGTACTGAC 
GAGGCGAAGA TGTCCTTCCT GGTGACTCTG AACAACGTGG AAGTCTGCAG TGAAAACATC 
TCCACTCTGA AGAAGACACT GGAGAGTGAC TGCACCAAGC TCTTCAGCCA GGGCATTGGA 
GGGGAGCAGG CCCAGGCCAA GTTTGACAGC TGCCTTTCTG ACTTGGCCGC CGTGTCCAAC 
AAATTCCGAG ACCTCTTGCA GGAAGGGCTG ACGGAGCTCA ACAGCACAGC CATCAAGCCA 
CAGGTGCAGC CTTGGATCAA CAGCTTTTTC TCCGTCTCCC ACAACATCGA GGAGGAAGAA 
TTCAATGACT ATGAGGCCAA CGACCCTTGG GTACAACAGT TCATCCTTAA CCTGGAGCAG 
CAAATGGCAG AGTTCAAGGC CAGCCTGTCC CCGGTCATCT ACGACAGCCT AACCGGCCTC 
ATGACTAGCC TTGTTGCCGT CGAGTTGGAG AAAGTGGTGC TGAAATCCAC CTTTAACCGG 
CTGGGTGGTC TGCAGTTTGA CAAGGAGCTG AGGTCGCTCA TTGCCTACCT TACCACGGTG 
ACCACCTGGA CCATCCGAGA CAAGTTTGCC CGGCTCTCCC AGATGGCCAC CATCCTCAAT 
CTGGAGCGGG TGACCGAGAT CCTCGATTAC TGGGGACCCA ATTCCGGCCC ATTGACGTGG 
CGCCTCACCC CTGCTGAAGT GCGCCAGGTG CTGGCCCTGC GGATAGACTT CCGCAGTGAA 
GATATCAAGA GGCTGCGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG4 ( XM_011522981.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011521283.1 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu49333
Clone ID Related Accession (Same CDS sequence)	XM_011522981.2 , NM_001365426.1 , XM_011522981.3
Accession Version	XM_011522981.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011522981.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGGAG TTCAGACTGC TTTGAGGAGT GAAGATTATG AGCAGGCTGC AGCACATACT 
CATCGCTACT TGTGCCTGGA CAAGTCGGTC ATTGAGCTCA GCCGACAGGG CAAAGAGGGG 
AGCATGATTG ATGCCAACCT GAAATTGCTG CAGGAAGCTG AGCAACGTCT CAAAGCCATT 
GTGGCAGAGA AGTTTGCCAT TGCCACCAAG GAAGGTGATC TGCCCCAGGT GGAGCGCTTC 
TTCAAGATCT TCCCACTGCT GGGTTTGCAT GAGGAGGGAT TAAGAAAGTT CTCGGAGTAC 
CTTTGCAAGC AGGTGGCCAG TAAAGCTGAG GAGAATCTGC TCATGGTGCT GGGGACAGAC 
ATGAGTGATC GGAGAGCTGC AGTCATCTTT GCAGATACAC TTACTCTTCT GTTTGAAGGG 
ATTGCCCGCA TTGTGGAGAC CCACCAGCCA ATAGTGGAGA CCTATTATGG GCCAGGGAGA 
CTCTATACCC TGATCAAATA TCTGCAGGTG GAATGTGACA GACAGGTGGA GAAGGTGGTA 
GACAAGTTCA TCAAGCAAAG GGACTACCAC CAGCAGTTCC GGCATGTTCA GAACAACCTG 
ATGAGAAATT CTACAACAGA AAAAATCGAA CCAAGAGAAC TGGACCCCAT CCTGACTGAG 
GTCACCCTGA TGAATGCCCG CAGTGAGCTA TACTTACGCT TCCTCAAGAA GAGGATTAGC 
TCTGATTTTG AGGTGGGAGA CTCCATGGCC TCAGAGGAAG TAAAGCAAGA GCACCAGAAG 
TGTCTGGACA AACTCCTCAA TAACTGCCTT TTGAGCTGTA CCATGCAGGA GCTAATTGGC 
TTATATGTTA CCATGGAGGA GTACTTCATG AGGGAGACTG TCAATAAGGC TGTGGCTCTG 
GACACCTATG AGAAGGGCCA GCTGACATCC AGCATGGTGG ATGATGTCTT CTACATTGTT 
AAGAAGTGCA TTGGGCGGGC TCTGTCCAGC TCCAGCATTG ACTGTCTCTG TGCCATGATC 
AACCTCGCCA CCACAGAGCT GGAGTCTGAC TTCAGGGATG TTCTGTGTAA TAAGCTGCGG 
ATGGGCTTTC CTGCCACCAC CTTCCAGGAC ATCCAGCGCG GGGTGACAAG TGCCGTGAAC 
ATCATGCACA GCAGCCTCCA GCAAGGCAAA TTTGACACAA AAGGCATCGA GAGTACTGAC 
GAGGCGAAGA TGTCCTTCCT GGTGACTCTG AACAACGTGG AAGTCTGCAG TGAAAACATC 
TCCACTCTGA AGAAGACACT GGAGAGTGAC TGCACCAAGC TCTTCAGCCA GGGCATTGGA 
GGGGAGCAGG CCCAGGCCAA GTTTGACAGC TGCCTTTCTG ACTTGGCCGC CGTGTCCAAC 
AAATTCCGAG ACCTCTTGCA GGAAGGGCTG ACGGAGCTCA ACAGCACAGC CATCAAGCCA 
CAGGTGCAGC CTTGGATCAA CAGCTTTTTC TCCGTCTCCC ACAACATCGA GGAGGAAGAA 
TTCAATGACT ATGAGGCCAA CGACCCTTGG GTACAACAGT TCATCCTTAA CCTGGAGCAG 
CAAATGGCAG AGTTCAAGGC CAGCCTGTCC CCGGTCATCT ACGACAGCCT AACCGGCCTC 
ATGACTAGCC TTGTTGCCGT CGAGTTGGAG AAAGTGGTGC TGAAATCCAC CTTTAACCGG 
CTGGGTGGTC TGCAGTTTGA CAAGGAGCTG AGGTCGCTCA TTGCCTACCT TACCACGGTG 
ACCACCTGGA CCATCCGAGA CAAGTTTGCC CGGCTCTCCC AGATGGCCAC CATCCTCAAT 
CTGGAGCGGG TGACCGAGAT CCTCGATTAC TGGGGACCCA ATTCCGGCCC ATTGACGTGG 
CGCCTCACCC CTGCTGAAGT GCGCCAGGTG CTGGCCCTGC GGATAGACTT CCGCAGTGAA 
GATATCAAGA GGCTGCGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011521283.1
CDS	598..2541
Translation	MDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	XM_011522981.2
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011522981.2

ORF Insert Sequence:

ATGGATGGAG TTCAGACTGC TTTGAGGAGT GAAGATTATG AGCAGGCTGC AGCACATACT 
CATCGCTACT TGTGCCTGGA CAAGTCGGTC ATTGAGCTCA GCCGACAGGG CAAAGAGGGG 
AGCATGATTG ATGCCAACCT GAAATTGCTG CAGGAAGCTG AGCAACGTCT CAAAGCCATT 
GTGGCAGAGA AGTTTGCCAT TGCCACCAAG GAAGGTGATC TGCCCCAGGT GGAGCGCTTC 
TTCAAGATCT TCCCACTGCT GGGTTTGCAT GAGGAGGGAT TAAGAAAGTT CTCGGAGTAC 
CTTTGCAAGC AGGTGGCCAG TAAAGCTGAG GAGAATCTGC TCATGGTGCT GGGGACAGAC 
ATGAGTGATC GGAGAGCTGC AGTCATCTTT GCAGATACAC TTACTCTTCT GTTTGAAGGG 
ATTGCCCGCA TTGTGGAGAC CCACCAGCCA ATAGTGGAGA CCTATTATGG GCCAGGGAGA 
CTCTATACCC TGATCAAATA TCTGCAGGTG GAATGTGACA GACAGGTGGA GAAGGTGGTA 
GACAAGTTCA TCAAGCAAAG GGACTACCAC CAGCAGTTCC GGCATGTTCA GAACAACCTG 
ATGAGAAATT CTACAACAGA AAAAATCGAA CCAAGAGAAC TGGACCCCAT CCTGACTGAG 
GTCACCCTGA TGAATGCCCG CAGTGAGCTA TACTTACGCT TCCTCAAGAA GAGGATTAGC 
TCTGATTTTG AGGTGGGAGA CTCCATGGCC TCAGAGGAAG TAAAGCAAGA GCACCAGAAG 
TGTCTGGACA AACTCCTCAA TAACTGCCTT TTGAGCTGTA CCATGCAGGA GCTAATTGGC 
TTATATGTTA CCATGGAGGA GTACTTCATG AGGGAGACTG TCAATAAGGC TGTGGCTCTG 
GACACCTATG AGAAGGGCCA GCTGACATCC AGCATGGTGG ATGATGTCTT CTACATTGTT 
AAGAAGTGCA TTGGGCGGGC TCTGTCCAGC TCCAGCATTG ACTGTCTCTG TGCCATGATC 
AACCTCGCCA CCACAGAGCT GGAGTCTGAC TTCAGGGATG TTCTGTGTAA TAAGCTGCGG 
ATGGGCTTTC CTGCCACCAC CTTCCAGGAC ATCCAGCGCG GGGTGACAAG TGCCGTGAAC 
ATCATGCACA GCAGCCTCCA GCAAGGCAAA TTTGACACAA AAGGCATCGA GAGTACTGAC 
GAGGCGAAGA TGTCCTTCCT GGTGACTCTG AACAACGTGG AAGTCTGCAG TGAAAACATC 
TCCACTCTGA AGAAGACACT GGAGAGTGAC TGCACCAAGC TCTTCAGCCA GGGCATTGGA 
GGGGAGCAGG CCCAGGCCAA GTTTGACAGC TGCCTTTCTG ACTTGGCCGC CGTGTCCAAC 
AAATTCCGAG ACCTCTTGCA GGAAGGGCTG ACGGAGCTCA ACAGCACAGC CATCAAGCCA 
CAGGTGCAGC CTTGGATCAA CAGCTTTTTC TCCGTCTCCC ACAACATCGA GGAGGAAGAA 
TTCAATGACT ATGAGGCCAA CGACCCTTGG GTACAACAGT TCATCCTTAA CCTGGAGCAG 
CAAATGGCAG AGTTCAAGGC CAGCCTGTCC CCGGTCATCT ACGACAGCCT AACCGGCCTC 
ATGACTAGCC TTGTTGCCGT CGAGTTGGAG AAAGTGGTGC TGAAATCCAC CTTTAACCGG 
CTGGGTGGTC TGCAGTTTGA CAAGGAGCTG AGGTCGCTCA TTGCCTACCT TACCACGGTG 
ACCACCTGGA CCATCCGAGA CAAGTTTGCC CGGCTCTCCC AGATGGCCAC CATCCTCAAT 
CTGGAGCGGG TGACCGAGAT CCTCGATTAC TGGGGACCCA ATTCCGGCCC ATTGACGTGG 
CGCCTCACCC CTGCTGAAGT GCGCCAGGTG CTGGCCCTGC GGATAGACTT CCGCAGTGAA 
GATATCAAGA GGCTGCGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG4 ( XM_011522981.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011521283.1 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X1, mRNA.

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CloneID	OHu49333
Clone ID Related Accession (Same CDS sequence)	XM_011522981.2 , NM_001365426.1 , XM_011522981.3
Accession Version	XM_011522981.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011522981.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGGAG TTCAGACTGC TTTGAGGAGT GAAGATTATG AGCAGGCTGC AGCACATACT 
CATCGCTACT TGTGCCTGGA CAAGTCGGTC ATTGAGCTCA GCCGACAGGG CAAAGAGGGG 
AGCATGATTG ATGCCAACCT GAAATTGCTG CAGGAAGCTG AGCAACGTCT CAAAGCCATT 
GTGGCAGAGA AGTTTGCCAT TGCCACCAAG GAAGGTGATC TGCCCCAGGT GGAGCGCTTC 
TTCAAGATCT TCCCACTGCT GGGTTTGCAT GAGGAGGGAT TAAGAAAGTT CTCGGAGTAC 
CTTTGCAAGC AGGTGGCCAG TAAAGCTGAG GAGAATCTGC TCATGGTGCT GGGGACAGAC 
ATGAGTGATC GGAGAGCTGC AGTCATCTTT GCAGATACAC TTACTCTTCT GTTTGAAGGG 
ATTGCCCGCA TTGTGGAGAC CCACCAGCCA ATAGTGGAGA CCTATTATGG GCCAGGGAGA 
CTCTATACCC TGATCAAATA TCTGCAGGTG GAATGTGACA GACAGGTGGA GAAGGTGGTA 
GACAAGTTCA TCAAGCAAAG GGACTACCAC CAGCAGTTCC GGCATGTTCA GAACAACCTG 
ATGAGAAATT CTACAACAGA AAAAATCGAA CCAAGAGAAC TGGACCCCAT CCTGACTGAG 
GTCACCCTGA TGAATGCCCG CAGTGAGCTA TACTTACGCT TCCTCAAGAA GAGGATTAGC 
TCTGATTTTG AGGTGGGAGA CTCCATGGCC TCAGAGGAAG TAAAGCAAGA GCACCAGAAG 
TGTCTGGACA AACTCCTCAA TAACTGCCTT TTGAGCTGTA CCATGCAGGA GCTAATTGGC 
TTATATGTTA CCATGGAGGA GTACTTCATG AGGGAGACTG TCAATAAGGC TGTGGCTCTG 
GACACCTATG AGAAGGGCCA GCTGACATCC AGCATGGTGG ATGATGTCTT CTACATTGTT 
AAGAAGTGCA TTGGGCGGGC TCTGTCCAGC TCCAGCATTG ACTGTCTCTG TGCCATGATC 
AACCTCGCCA CCACAGAGCT GGAGTCTGAC TTCAGGGATG TTCTGTGTAA TAAGCTGCGG 
ATGGGCTTTC CTGCCACCAC CTTCCAGGAC ATCCAGCGCG GGGTGACAAG TGCCGTGAAC 
ATCATGCACA GCAGCCTCCA GCAAGGCAAA TTTGACACAA AAGGCATCGA GAGTACTGAC 
GAGGCGAAGA TGTCCTTCCT GGTGACTCTG AACAACGTGG AAGTCTGCAG TGAAAACATC 
TCCACTCTGA AGAAGACACT GGAGAGTGAC TGCACCAAGC TCTTCAGCCA GGGCATTGGA 
GGGGAGCAGG CCCAGGCCAA GTTTGACAGC TGCCTTTCTG ACTTGGCCGC CGTGTCCAAC 
AAATTCCGAG ACCTCTTGCA GGAAGGGCTG ACGGAGCTCA ACAGCACAGC CATCAAGCCA 
CAGGTGCAGC CTTGGATCAA CAGCTTTTTC TCCGTCTCCC ACAACATCGA GGAGGAAGAA 
TTCAATGACT ATGAGGCCAA CGACCCTTGG GTACAACAGT TCATCCTTAA CCTGGAGCAG 
CAAATGGCAG AGTTCAAGGC CAGCCTGTCC CCGGTCATCT ACGACAGCCT AACCGGCCTC 
ATGACTAGCC TTGTTGCCGT CGAGTTGGAG AAAGTGGTGC TGAAATCCAC CTTTAACCGG 
CTGGGTGGTC TGCAGTTTGA CAAGGAGCTG AGGTCGCTCA TTGCCTACCT TACCACGGTG 
ACCACCTGGA CCATCCGAGA CAAGTTTGCC CGGCTCTCCC AGATGGCCAC CATCCTCAAT 
CTGGAGCGGG TGACCGAGAT CCTCGATTAC TGGGGACCCA ATTCCGGCCC ATTGACGTGG 
CGCCTCACCC CTGCTGAAGT GCGCCAGGTG CTGGCCCTGC GGATAGACTT CCGCAGTGAA 
GATATCAAGA GGCTGCGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011521283.1
CDS	608..2551
Translation	MDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	XM_011522981.3
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011522981.3

ORF Insert Sequence:

ATGGATGGAG TTCAGACTGC TTTGAGGAGT GAAGATTATG AGCAGGCTGC AGCACATACT 
CATCGCTACT TGTGCCTGGA CAAGTCGGTC ATTGAGCTCA GCCGACAGGG CAAAGAGGGG 
AGCATGATTG ATGCCAACCT GAAATTGCTG CAGGAAGCTG AGCAACGTCT CAAAGCCATT 
GTGGCAGAGA AGTTTGCCAT TGCCACCAAG GAAGGTGATC TGCCCCAGGT GGAGCGCTTC 
TTCAAGATCT TCCCACTGCT GGGTTTGCAT GAGGAGGGAT TAAGAAAGTT CTCGGAGTAC 
CTTTGCAAGC AGGTGGCCAG TAAAGCTGAG GAGAATCTGC TCATGGTGCT GGGGACAGAC 
ATGAGTGATC GGAGAGCTGC AGTCATCTTT GCAGATACAC TTACTCTTCT GTTTGAAGGG 
ATTGCCCGCA TTGTGGAGAC CCACCAGCCA ATAGTGGAGA CCTATTATGG GCCAGGGAGA 
CTCTATACCC TGATCAAATA TCTGCAGGTG GAATGTGACA GACAGGTGGA GAAGGTGGTA 
GACAAGTTCA TCAAGCAAAG GGACTACCAC CAGCAGTTCC GGCATGTTCA GAACAACCTG 
ATGAGAAATT CTACAACAGA AAAAATCGAA CCAAGAGAAC TGGACCCCAT CCTGACTGAG 
GTCACCCTGA TGAATGCCCG CAGTGAGCTA TACTTACGCT TCCTCAAGAA GAGGATTAGC 
TCTGATTTTG AGGTGGGAGA CTCCATGGCC TCAGAGGAAG TAAAGCAAGA GCACCAGAAG 
TGTCTGGACA AACTCCTCAA TAACTGCCTT TTGAGCTGTA CCATGCAGGA GCTAATTGGC 
TTATATGTTA CCATGGAGGA GTACTTCATG AGGGAGACTG TCAATAAGGC TGTGGCTCTG 
GACACCTATG AGAAGGGCCA GCTGACATCC AGCATGGTGG ATGATGTCTT CTACATTGTT 
AAGAAGTGCA TTGGGCGGGC TCTGTCCAGC TCCAGCATTG ACTGTCTCTG TGCCATGATC 
AACCTCGCCA CCACAGAGCT GGAGTCTGAC TTCAGGGATG TTCTGTGTAA TAAGCTGCGG 
ATGGGCTTTC CTGCCACCAC CTTCCAGGAC ATCCAGCGCG GGGTGACAAG TGCCGTGAAC 
ATCATGCACA GCAGCCTCCA GCAAGGCAAA TTTGACACAA AAGGCATCGA GAGTACTGAC 
GAGGCGAAGA TGTCCTTCCT GGTGACTCTG AACAACGTGG AAGTCTGCAG TGAAAACATC 
TCCACTCTGA AGAAGACACT GGAGAGTGAC TGCACCAAGC TCTTCAGCCA GGGCATTGGA 
GGGGAGCAGG CCCAGGCCAA GTTTGACAGC TGCCTTTCTG ACTTGGCCGC CGTGTCCAAC 
AAATTCCGAG ACCTCTTGCA GGAAGGGCTG ACGGAGCTCA ACAGCACAGC CATCAAGCCA 
CAGGTGCAGC CTTGGATCAA CAGCTTTTTC TCCGTCTCCC ACAACATCGA GGAGGAAGAA 
TTCAATGACT ATGAGGCCAA CGACCCTTGG GTACAACAGT TCATCCTTAA CCTGGAGCAG 
CAAATGGCAG AGTTCAAGGC CAGCCTGTCC CCGGTCATCT ACGACAGCCT AACCGGCCTC 
ATGACTAGCC TTGTTGCCGT CGAGTTGGAG AAAGTGGTGC TGAAATCCAC CTTTAACCGG 
CTGGGTGGTC TGCAGTTTGA CAAGGAGCTG AGGTCGCTCA TTGCCTACCT TACCACGGTG 
ACCACCTGGA CCATCCGAGA CAAGTTTGCC CGGCTCTCCC AGATGGCCAC CATCCTCAAT 
CTGGAGCGGG TGACCGAGAT CCTCGATTAC TGGGGACCCA ATTCCGGCCC ATTGACGTGG 
CGCCTCACCC CTGCTGAAGT GCGCCAGGTG CTGGCCCTGC GGATAGACTT CCGCAGTGAA 
GATATCAAGA GGCTGCGCCT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG4 ( XM_024450224.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024305992.1 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X5, mRNA.

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CloneID	OHu104123
Clone ID Related Accession (Same CDS sequence)	XM_024450224.1
Accession Version	XM_024450224.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAAAG TTTGGAGTGA CCAGCAAGAG GCCAATAGAT GTGGGGGTGG GGAAGAATAT 
TCTCATTCCT GTGGTATGTT GCAGTTCCGG CATGTTCAGA ACAACCTGAT GAGAAATTCT 
ACAACAGAAA AAATCGAACC AAGAGAACTG GACCCCATCC TGACTGAGGT CACCCTGATG 
AATGCCCGCA GTGAGCTATA CTTACGCTTC CTCAAGAAGA GGATTAGCTC TGATTTTGAG 
GTGGGAGACT CCATGGCCTC AGAGGAAGTA AAGCAAGAGC ACCAGAAGTG TCTGGACAAA 
CTCCTCAATA ACTGCCTTTT GAGCTGTACC ATGCAGGAGC TAATTGGCTT ATATGTTACC 
ATGGAGGAGT ACTTCATGAG GGAGACTGTC AATAAGGCTG TGGCTCTGGA CACCTATGAG 
AAGGGCCAGC TGACATCCAG CATGGTGGAT GATGTCTTCT ACATTGTTAA GAAGTGCATT 
GGGCGGGCTC TGTCCAGCTC CAGCATTGAC TGTCTCTGTG CCATGATCAA CCTCGCCACC 
ACAGAGCTGG AGTCTGACTT CAGGGATGTT CTGTGTAATA AGCTGCGGAT GGGCTTTCCT 
GCCACCACCT TCCAGGACAT CCAGCGCGGG GTGACAAGTG CCGTGAACAT CATGCACAGC 
AGCCTCCAGC AAGGCAAATT TGACACAAAA GGCATCGAGA GTACTGACGA GGCGAAGATG 
TCCTTCCTGA GTGACTGCAC CAAGCTCTTC AGCCAGGGCA TTGGAGGGGA GCAGGCCCAG 
GCCAAGTTTG ACAGCTGCCT TTCTGACTTG GCCGCCGTGT CCAACAAATT CCGAGACCTC 
TTGCAGGAAG GGCTGACGGA GCTCAACAGC ACAGCCATCA AGCCACAGGT GCAGCCTTGG 
ATCAACAGCT TTTTCTCCGT CTCCCACAAC ATCGAGGAGG AAGAATTCAA TGACTATGAG 
GCCAACGACC CTTGGGTACA ACAGTTCATC CTTAACCTGG AGCAGCAAAT GGCAGAGTTC 
AAGGCCAGCC TGTCCCCGGT CATCTACGAC AGCCTAACCG GCCTCATGAC TAGCCTTGTT 
GCCGTCGAGT TGGAGAAAGT GGTGCTGAAA TCCACCTTTA ACCGGCTGGG TGGTCTGCAG 
TTTGACAAGG AGCTGAGGTC GCTCATTGCC TACCTTACCA CGGTGACCAC CTGGACCATC 
CGAGACAAGT TTGCCCGGCT CTCCCAGATG GCCACCATCC TCAATCTGGA GCGGGTGACC 
GAGATCCTCG ATTACTGGGG ACCCAATTCC GGCCCATTGA CGTGGCGCCT CACCCCTGCT 
GAAGTGCGCC AGGTGCTGGC CCTGCGGATA GACTTCCGCA GTGAAGATAT CAAGAGGCTG 
CGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024305992.1
CDS	1852..3240
Translation	MPKVWSDQQEANRCGGGEEYSHSCGMLQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLSDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	XM_024450224.1
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450224.1

ORF Insert Sequence:

ATGCCAAAAG TTTGGAGTGA CCAGCAAGAG GCCAATAGAT GTGGGGGTGG GGAAGAATAT 
TCTCATTCCT GTGGTATGTT GCAGTTCCGG CATGTTCAGA ACAACCTGAT GAGAAATTCT 
ACAACAGAAA AAATCGAACC AAGAGAACTG GACCCCATCC TGACTGAGGT CACCCTGATG 
AATGCCCGCA GTGAGCTATA CTTACGCTTC CTCAAGAAGA GGATTAGCTC TGATTTTGAG 
GTGGGAGACT CCATGGCCTC AGAGGAAGTA AAGCAAGAGC ACCAGAAGTG TCTGGACAAA 
CTCCTCAATA ACTGCCTTTT GAGCTGTACC ATGCAGGAGC TAATTGGCTT ATATGTTACC 
ATGGAGGAGT ACTTCATGAG GGAGACTGTC AATAAGGCTG TGGCTCTGGA CACCTATGAG 
AAGGGCCAGC TGACATCCAG CATGGTGGAT GATGTCTTCT ACATTGTTAA GAAGTGCATT 
GGGCGGGCTC TGTCCAGCTC CAGCATTGAC TGTCTCTGTG CCATGATCAA CCTCGCCACC 
ACAGAGCTGG AGTCTGACTT CAGGGATGTT CTGTGTAATA AGCTGCGGAT GGGCTTTCCT 
GCCACCACCT TCCAGGACAT CCAGCGCGGG GTGACAAGTG CCGTGAACAT CATGCACAGC 
AGCCTCCAGC AAGGCAAATT TGACACAAAA GGCATCGAGA GTACTGACGA GGCGAAGATG 
TCCTTCCTGA GTGACTGCAC CAAGCTCTTC AGCCAGGGCA TTGGAGGGGA GCAGGCCCAG 
GCCAAGTTTG ACAGCTGCCT TTCTGACTTG GCCGCCGTGT CCAACAAATT CCGAGACCTC 
TTGCAGGAAG GGCTGACGGA GCTCAACAGC ACAGCCATCA AGCCACAGGT GCAGCCTTGG 
ATCAACAGCT TTTTCTCCGT CTCCCACAAC ATCGAGGAGG AAGAATTCAA TGACTATGAG 
GCCAACGACC CTTGGGTACA ACAGTTCATC CTTAACCTGG AGCAGCAAAT GGCAGAGTTC 
AAGGCCAGCC TGTCCCCGGT CATCTACGAC AGCCTAACCG GCCTCATGAC TAGCCTTGTT 
GCCGTCGAGT TGGAGAAAGT GGTGCTGAAA TCCACCTTTA ACCGGCTGGG TGGTCTGCAG 
TTTGACAAGG AGCTGAGGTC GCTCATTGCC TACCTTACCA CGGTGACCAC CTGGACCATC 
CGAGACAAGT TTGCCCGGCT CTCCCAGATG GCCACCATCC TCAATCTGGA GCGGGTGACC 
GAGATCCTCG ATTACTGGGG ACCCAATTCC GGCCCATTGA CGTGGCGCCT CACCCCTGCT 
GAAGTGCGCC AGGTGCTGGC CCTGCGGATA GACTTCCGCA GTGAAGATAT CAAGAGGCTG 
CGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG4 ( NM_001195139.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001182068.1 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 2, mRNA.

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CloneID	OHu16785
Clone ID Related Accession (Same CDS sequence)	NM_001195139.1
Accession Version	NM_001195139.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096557.1, BP282697.1, AU125729.1 and AL050101.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.404568.1, BC027726.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGACCA AGATGGCGGA CCTTGATTCG CCTCCGAAGC TGTCAGGGGT GCAGCAGCCG 
TCTGAGGGGG TGGGAGGTGG CCGCTGCTCC GAAATCTCCG CTGAGCTCAT TCGCTCCCTG 
ACAGAGCTGC AGGAGCTGGA GGCTGTATAC GAACGGCTCT GCGGCGAGGA GAAAGTGGTG 
GAGAGAGAGC TGGATGCTCT TTTGGAACAG CAAAACACCA TTGAAAGTAA GATGGTCACT 
CTCCACCGAA TGGGTCCTAA TCTGCAGCTG ATTGAGGGAG ATGCAAAGCA GCTGGCTGGA 
ATGATCACCT TTACCTGCAA CCTGGCTGAG AATGTGTCCA GCAAAGTTCG TCAGCTTGAC 
CTGGCCAAGA ACCGCCTCTA TCAGGCCATT CAGAGAGCTG ATGACATCTT GGACCTGAAG 
TTCTGCATGG ATGGAGTTCA GACTGCTTTG AGGAGTGAAG ATTATGAGCA GGCTGCAGCA 
CATACTCATC GCTACTTGTG CCTGGACAAG TCGGTCATTG AGCTCAGCCG ACAGGGCAAA 
GAGGGGAGCA TGATTGATGC CAACCTGAAA TTGCTGCAGG AAGCTGAGCA ACGTCTCAAA 
GCCATTGTGG CAGAGAAGTT TGCCATTGCC ACCAAGGAAG GTGATCTGCC CCAGGTGGAG 
CGCTTCTTCA AGATCTTCCC ACTGCTGGGT TTGCATGAGG AGGGATTAAG AAAGTTCTCG 
GAGTACCTTT GCAAGCAGGT GGCCAGTAAA GCTGAGGAGA ATCTGCTCAT GGTGCTGGGG 
ACAGACATGA GTGATCGGAG AGCTGCAGTC ATCTTTGCAG ATACACTTAC TCTTCTGTTT 
GAAGGGATTG CCCGCATTGT GGAGACCCAC CAGCCAATAG TGGAGACCTA TTATGGGCCA 
GGGAGACTCT ATACCCTGAT CAAATATCTG CAGGTGGAAT GTGACAGACA GGTGGAGAAG 
GTGGTAGACA AGTTCATCAA GCAAAGGGAC TACCACCAGC AGTTCCGGCA TGTTCAGAAC 
AACCTGATGA GAAATTCTAC AACAGAAAAA ATCGAACCAA GAGAACTGGA CCCCATCCTG 
ACTGAGGTCA CCCTGATGAA TGCCCGCAGT GAGCTATACT TACGCTTCCT CAAGAAGAGG 
ATTAGCTCTG ATTTTGAGGT GGGAGACTCC ATGGCCTCAG AGGAAGTAAA GCAAGAGCAC 
CAGAAGTGTC TGGACAAACT CCTCAATAAC TGCCTTTTGA GCTGTACCAT GCAGGAGCTA 
ATTGGCTTAT ATGTTACCAT GGAGGAGTAC TTCATGAGGG AGACTGTCAA TAAGGCTGTG 
GCTCTGGACA CCTATGAGAA GGGCCAGCTG ACATCCAGCA TGGTGGATGA TGTCTTCTAC 
ATTGTTAAGA AGTGCATTGG GCGGGCTCTG TCCAGCTCCA GCATTGACTG TCTCTGTGCC 
ATGATCAACC TCGCCACCAC AGAGCTGGAG TCTGACTTCA GGGATGTTCT GTGTAATAAG 
CTGCGGATGG GCTTTCCTGC CACCACCTTC CAGGACATCC AGCGCGGGGT GACAAGTGCC 
GTGAACATCA TGCACAGCAG CCTCCAGCAA GGCAAATTTG ACACAAAAGG CATCGAGAGT 
ACTGACGAGG CGAAGATGTC CTTCCTGAGT GACTGCACCA AGCTCTTCAG CCAGGGCATT 
GGAGGGGAGC AGGCCCAGGC CAAGTTTGAC AGCTGCCTTT CTGACTTGGC CGCCGTGTCC 
AACAAATTCC GAGACCTCTT GCAGGAAGGG CTGACGGAGC TCAACAGCAC AGCCATCAAG 
CCACAGGTGC AGCCTTGGAT CAACAGCTTT TTCTCCGTCT CCCACAACAT CGAGGAGGAA 
GAATTCAATG ACTATGAGGC CAACGACCCT TGGGTACAAC AGTTCATCCT TAACCTGGAG 
CAGCAAATGG CAGAGTTCAA GGCCAGCCTG TCCCCGGTCA TCTACGACAG CCTAACCGGC 
CTCATGACTA GCCTTGTTGC CGTCGAGTTG GAGAAAGTGG TGCTGAAATC CACCTTTAAC 
CGGCTGGGTG GTCTGCAGTT TGACAAGGAG CTGAGGTCGC TCATTGCCTA CCTTACCACG 
GTGACCACCT GGACCATCCG AGACAAGTTT GCCCGGCTCT CCCAGATGGC CACCATCCTC 
AATCTGGAGC GGGTGACCGA GATCCTCGAT TACTGGGGAC CCAATTCCGG CCCATTGACG 
TGGCGCCTCA CCCCTGCTGA AGTGCGCCAG GTGCTGGCCC TGCGGATAGA CTTCCGCAGT 
GAAGATATCA AGAGGCTGCG CCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001182068.1
CDS	12..2318
Translation	MGTKMADLDSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLSDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	NM_001195139.1
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001195139.1

ORF Insert Sequence:

ATGGGGACCA AGATGGCGGA CCTTGATTCG CCTCCGAAGC TGTCAGGGGT GCAGCAGCCG 
TCTGAGGGGG TGGGAGGTGG CCGCTGCTCC GAAATCTCCG CTGAGCTCAT TCGCTCCCTG 
ACAGAGCTGC AGGAGCTGGA GGCTGTATAC GAACGGCTCT GCGGCGAGGA GAAAGTGGTG 
GAGAGAGAGC TGGATGCTCT TTTGGAACAG CAAAACACCA TTGAAAGTAA GATGGTCACT 
CTCCACCGAA TGGGTCCTAA TCTGCAGCTG ATTGAGGGAG ATGCAAAGCA GCTGGCTGGA 
ATGATCACCT TTACCTGCAA CCTGGCTGAG AATGTGTCCA GCAAAGTTCG TCAGCTTGAC 
CTGGCCAAGA ACCGCCTCTA TCAGGCCATT CAGAGAGCTG ATGACATCTT GGACCTGAAG 
TTCTGCATGG ATGGAGTTCA GACTGCTTTG AGGAGTGAAG ATTATGAGCA GGCTGCAGCA 
CATACTCATC GCTACTTGTG CCTGGACAAG TCGGTCATTG AGCTCAGCCG ACAGGGCAAA 
GAGGGGAGCA TGATTGATGC CAACCTGAAA TTGCTGCAGG AAGCTGAGCA ACGTCTCAAA 
GCCATTGTGG CAGAGAAGTT TGCCATTGCC ACCAAGGAAG GTGATCTGCC CCAGGTGGAG 
CGCTTCTTCA AGATCTTCCC ACTGCTGGGT TTGCATGAGG AGGGATTAAG AAAGTTCTCG 
GAGTACCTTT GCAAGCAGGT GGCCAGTAAA GCTGAGGAGA ATCTGCTCAT GGTGCTGGGG 
ACAGACATGA GTGATCGGAG AGCTGCAGTC ATCTTTGCAG ATACACTTAC TCTTCTGTTT 
GAAGGGATTG CCCGCATTGT GGAGACCCAC CAGCCAATAG TGGAGACCTA TTATGGGCCA 
GGGAGACTCT ATACCCTGAT CAAATATCTG CAGGTGGAAT GTGACAGACA GGTGGAGAAG 
GTGGTAGACA AGTTCATCAA GCAAAGGGAC TACCACCAGC AGTTCCGGCA TGTTCAGAAC 
AACCTGATGA GAAATTCTAC AACAGAAAAA ATCGAACCAA GAGAACTGGA CCCCATCCTG 
ACTGAGGTCA CCCTGATGAA TGCCCGCAGT GAGCTATACT TACGCTTCCT CAAGAAGAGG 
ATTAGCTCTG ATTTTGAGGT GGGAGACTCC ATGGCCTCAG AGGAAGTAAA GCAAGAGCAC 
CAGAAGTGTC TGGACAAACT CCTCAATAAC TGCCTTTTGA GCTGTACCAT GCAGGAGCTA 
ATTGGCTTAT ATGTTACCAT GGAGGAGTAC TTCATGAGGG AGACTGTCAA TAAGGCTGTG 
GCTCTGGACA CCTATGAGAA GGGCCAGCTG ACATCCAGCA TGGTGGATGA TGTCTTCTAC 
ATTGTTAAGA AGTGCATTGG GCGGGCTCTG TCCAGCTCCA GCATTGACTG TCTCTGTGCC 
ATGATCAACC TCGCCACCAC AGAGCTGGAG TCTGACTTCA GGGATGTTCT GTGTAATAAG 
CTGCGGATGG GCTTTCCTGC CACCACCTTC CAGGACATCC AGCGCGGGGT GACAAGTGCC 
GTGAACATCA TGCACAGCAG CCTCCAGCAA GGCAAATTTG ACACAAAAGG CATCGAGAGT 
ACTGACGAGG CGAAGATGTC CTTCCTGAGT GACTGCACCA AGCTCTTCAG CCAGGGCATT 
GGAGGGGAGC AGGCCCAGGC CAAGTTTGAC AGCTGCCTTT CTGACTTGGC CGCCGTGTCC 
AACAAATTCC GAGACCTCTT GCAGGAAGGG CTGACGGAGC TCAACAGCAC AGCCATCAAG 
CCACAGGTGC AGCCTTGGAT CAACAGCTTT TTCTCCGTCT CCCACAACAT CGAGGAGGAA 
GAATTCAATG ACTATGAGGC CAACGACCCT TGGGTACAAC AGTTCATCCT TAACCTGGAG 
CAGCAAATGG CAGAGTTCAA GGCCAGCCTG TCCCCGGTCA TCTACGACAG CCTAACCGGC 
CTCATGACTA GCCTTGTTGC CGTCGAGTTG GAGAAAGTGG TGCTGAAATC CACCTTTAAC 
CGGCTGGGTG GTCTGCAGTT TGACAAGGAG CTGAGGTCGC TCATTGCCTA CCTTACCACG 
GTGACCACCT GGACCATCCG AGACAAGTTT GCCCGGCTCT CCCAGATGGC CACCATCCTC 
AATCTGGAGC GGGTGACCGA GATCCTCGAT TACTGGGGAC CCAATTCCGG CCCATTGACG 
TGGCGCCTCA CCCCTGCTGA AGTGCGCCAG GTGCTGGCCC TGCGGATAGA CTTCCGCAGT 
GAAGATATCA AGAGGCTGCG CCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG4 ( NM_015386.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056201.2 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17980
Clone ID Related Accession (Same CDS sequence)	NM_015386.2 , NM_015386.3
Accession Version	NM_015386.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2370bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096557.1, BP282697.1, AU125729.1 and AL050101.1. This sequence is a reference standard in the RefSeqGene project. On Nov 30, 2006 this sequence version replaced NM_015386.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1660809.118636.1, SRR1803616.277363.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGACCA AGATGGCGGA CCTTGATTCG CCTCCGAAGC TGTCAGGGGT GCAGCAGCCG 
TCTGAGGGGG TGGGAGGTGG CCGCTGCTCC GAAATCTCCG CTGAGCTCAT TCGCTCCCTG 
ACAGAGCTGC AGGAGCTGGA GGCTGTATAC GAACGGCTCT GCGGCGAGGA GAAAGTGGTG 
GAGAGAGAGC TGGATGCTCT TTTGGAACAG CAAAACACCA TTGAAAGTAA GATGGTCACT 
CTCCACCGAA TGGGTCCTAA TCTGCAGCTG ATTGAGGGAG ATGCAAAGCA GCTGGCTGGA 
ATGATCACCT TTACCTGCAA CCTGGCTGAG AATGTGTCCA GCAAAGTTCG TCAGCTTGAC 
CTGGCCAAGA ACCGCCTCTA TCAGGCCATT CAGAGAGCTG ATGACATCTT GGACCTGAAG 
TTCTGCATGG ATGGAGTTCA GACTGCTTTG AGGAGTGAAG ATTATGAGCA GGCTGCAGCA 
CATACTCATC GCTACTTGTG CCTGGACAAG TCGGTCATTG AGCTCAGCCG ACAGGGCAAA 
GAGGGGAGCA TGATTGATGC CAACCTGAAA TTGCTGCAGG AAGCTGAGCA ACGTCTCAAA 
GCCATTGTGG CAGAGAAGTT TGCCATTGCC ACCAAGGAAG GTGATCTGCC CCAGGTGGAG 
CGCTTCTTCA AGATCTTCCC ACTGCTGGGT TTGCATGAGG AGGGATTAAG AAAGTTCTCG 
GAGTACCTTT GCAAGCAGGT GGCCAGTAAA GCTGAGGAGA ATCTGCTCAT GGTGCTGGGG 
ACAGACATGA GTGATCGGAG AGCTGCAGTC ATCTTTGCAG ATACACTTAC TCTTCTGTTT 
GAAGGGATTG CCCGCATTGT GGAGACCCAC CAGCCAATAG TGGAGACCTA TTATGGGCCA 
GGGAGACTCT ATACCCTGAT CAAATATCTG CAGGTGGAAT GTGACAGACA GGTGGAGAAG 
GTGGTAGACA AGTTCATCAA GCAAAGGGAC TACCACCAGC AGTTCCGGCA TGTTCAGAAC 
AACCTGATGA GAAATTCTAC AACAGAAAAA ATCGAACCAA GAGAACTGGA CCCCATCCTG 
ACTGAGGTCA CCCTGATGAA TGCCCGCAGT GAGCTATACT TACGCTTCCT CAAGAAGAGG 
ATTAGCTCTG ATTTTGAGGT GGGAGACTCC ATGGCCTCAG AGGAAGTAAA GCAAGAGCAC 
CAGAAGTGTC TGGACAAACT CCTCAATAAC TGCCTTTTGA GCTGTACCAT GCAGGAGCTA 
ATTGGCTTAT ATGTTACCAT GGAGGAGTAC TTCATGAGGG AGACTGTCAA TAAGGCTGTG 
GCTCTGGACA CCTATGAGAA GGGCCAGCTG ACATCCAGCA TGGTGGATGA TGTCTTCTAC 
ATTGTTAAGA AGTGCATTGG GCGGGCTCTG TCCAGCTCCA GCATTGACTG TCTCTGTGCC 
ATGATCAACC TCGCCACCAC AGAGCTGGAG TCTGACTTCA GGGATGTTCT GTGTAATAAG 
CTGCGGATGG GCTTTCCTGC CACCACCTTC CAGGACATCC AGCGCGGGGT GACAAGTGCC 
GTGAACATCA TGCACAGCAG CCTCCAGCAA GGCAAATTTG ACACAAAAGG CATCGAGAGT 
ACTGACGAGG CGAAGATGTC CTTCCTGGTG ACTCTGAACA ACGTGGAAGT CTGCAGTGAA 
AACATCTCCA CTCTGAAGAA GACACTGGAG AGTGACTGCA CCAAGCTCTT CAGCCAGGGC 
ATTGGAGGGG AGCAGGCCCA GGCCAAGTTT GACAGCTGCC TTTCTGACTT GGCCGCCGTG 
TCCAACAAAT TCCGAGACCT CTTGCAGGAA GGGCTGACGG AGCTCAACAG CACAGCCATC 
AAGCCACAGG TGCAGCCTTG GATCAACAGC TTTTTCTCCG TCTCCCACAA CATCGAGGAG 
GAAGAATTCA ATGACTATGA GGCCAACGAC CCTTGGGTAC AACAGTTCAT CCTTAACCTG 
GAGCAGCAAA TGGCAGAGTT CAAGGCCAGC CTGTCCCCGG TCATCTACGA CAGCCTAACC 
GGCCTCATGA CTAGCCTTGT TGCCGTCGAG TTGGAGAAAG TGGTGCTGAA ATCCACCTTT 
AACCGGCTGG GTGGTCTGCA GTTTGACAAG GAGCTGAGGT CGCTCATTGC CTACCTTACC 
ACGGTGACCA CCTGGACCAT CCGAGACAAG TTTGCCCGGC TCTCCCAGAT GGCCACCATC 
CTCAATCTGG AGCGGGTGAC CGAGATCCTC GATTACTGGG GACCCAATTC CGGCCCATTG 
ACGTGGCGCC TCACCCCTGC TGAAGTGCGC CAGGTGCTGG CCCTGCGGAT AGACTTCCGC 
AGTGAAGATA TCAAGAGGCT GCGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056201.2
CDS	12..2381
Translation	MGTKMADLDSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	NM_015386.2
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015386.2

ORF Insert Sequence:

ATGGGGACCA AGATGGCGGA CCTTGATTCG CCTCCGAAGC TGTCAGGGGT GCAGCAGCCG 
TCTGAGGGGG TGGGAGGTGG CCGCTGCTCC GAAATCTCCG CTGAGCTCAT TCGCTCCCTG 
ACAGAGCTGC AGGAGCTGGA GGCTGTATAC GAACGGCTCT GCGGCGAGGA GAAAGTGGTG 
GAGAGAGAGC TGGATGCTCT TTTGGAACAG CAAAACACCA TTGAAAGTAA GATGGTCACT 
CTCCACCGAA TGGGTCCTAA TCTGCAGCTG ATTGAGGGAG ATGCAAAGCA GCTGGCTGGA 
ATGATCACCT TTACCTGCAA CCTGGCTGAG AATGTGTCCA GCAAAGTTCG TCAGCTTGAC 
CTGGCCAAGA ACCGCCTCTA TCAGGCCATT CAGAGAGCTG ATGACATCTT GGACCTGAAG 
TTCTGCATGG ATGGAGTTCA GACTGCTTTG AGGAGTGAAG ATTATGAGCA GGCTGCAGCA 
CATACTCATC GCTACTTGTG CCTGGACAAG TCGGTCATTG AGCTCAGCCG ACAGGGCAAA 
GAGGGGAGCA TGATTGATGC CAACCTGAAA TTGCTGCAGG AAGCTGAGCA ACGTCTCAAA 
GCCATTGTGG CAGAGAAGTT TGCCATTGCC ACCAAGGAAG GTGATCTGCC CCAGGTGGAG 
CGCTTCTTCA AGATCTTCCC ACTGCTGGGT TTGCATGAGG AGGGATTAAG AAAGTTCTCG 
GAGTACCTTT GCAAGCAGGT GGCCAGTAAA GCTGAGGAGA ATCTGCTCAT GGTGCTGGGG 
ACAGACATGA GTGATCGGAG AGCTGCAGTC ATCTTTGCAG ATACACTTAC TCTTCTGTTT 
GAAGGGATTG CCCGCATTGT GGAGACCCAC CAGCCAATAG TGGAGACCTA TTATGGGCCA 
GGGAGACTCT ATACCCTGAT CAAATATCTG CAGGTGGAAT GTGACAGACA GGTGGAGAAG 
GTGGTAGACA AGTTCATCAA GCAAAGGGAC TACCACCAGC AGTTCCGGCA TGTTCAGAAC 
AACCTGATGA GAAATTCTAC AACAGAAAAA ATCGAACCAA GAGAACTGGA CCCCATCCTG 
ACTGAGGTCA CCCTGATGAA TGCCCGCAGT GAGCTATACT TACGCTTCCT CAAGAAGAGG 
ATTAGCTCTG ATTTTGAGGT GGGAGACTCC ATGGCCTCAG AGGAAGTAAA GCAAGAGCAC 
CAGAAGTGTC TGGACAAACT CCTCAATAAC TGCCTTTTGA GCTGTACCAT GCAGGAGCTA 
ATTGGCTTAT ATGTTACCAT GGAGGAGTAC TTCATGAGGG AGACTGTCAA TAAGGCTGTG 
GCTCTGGACA CCTATGAGAA GGGCCAGCTG ACATCCAGCA TGGTGGATGA TGTCTTCTAC 
ATTGTTAAGA AGTGCATTGG GCGGGCTCTG TCCAGCTCCA GCATTGACTG TCTCTGTGCC 
ATGATCAACC TCGCCACCAC AGAGCTGGAG TCTGACTTCA GGGATGTTCT GTGTAATAAG 
CTGCGGATGG GCTTTCCTGC CACCACCTTC CAGGACATCC AGCGCGGGGT GACAAGTGCC 
GTGAACATCA TGCACAGCAG CCTCCAGCAA GGCAAATTTG ACACAAAAGG CATCGAGAGT 
ACTGACGAGG CGAAGATGTC CTTCCTGGTG ACTCTGAACA ACGTGGAAGT CTGCAGTGAA 
AACATCTCCA CTCTGAAGAA GACACTGGAG AGTGACTGCA CCAAGCTCTT CAGCCAGGGC 
ATTGGAGGGG AGCAGGCCCA GGCCAAGTTT GACAGCTGCC TTTCTGACTT GGCCGCCGTG 
TCCAACAAAT TCCGAGACCT CTTGCAGGAA GGGCTGACGG AGCTCAACAG CACAGCCATC 
AAGCCACAGG TGCAGCCTTG GATCAACAGC TTTTTCTCCG TCTCCCACAA CATCGAGGAG 
GAAGAATTCA ATGACTATGA GGCCAACGAC CCTTGGGTAC AACAGTTCAT CCTTAACCTG 
GAGCAGCAAA TGGCAGAGTT CAAGGCCAGC CTGTCCCCGG TCATCTACGA CAGCCTAACC 
GGCCTCATGA CTAGCCTTGT TGCCGTCGAG TTGGAGAAAG TGGTGCTGAA ATCCACCTTT 
AACCGGCTGG GTGGTCTGCA GTTTGACAAG GAGCTGAGGT CGCTCATTGC CTACCTTACC 
ACGGTGACCA CCTGGACCAT CCGAGACAAG TTTGCCCGGC TCTCCCAGAT GGCCACCATC 
CTCAATCTGG AGCGGGTGAC CGAGATCCTC GATTACTGGG GACCCAATTC CGGCCCATTG 
ACGTGGCGCC TCACCCCTGC TGAAGTGCGC CAGGTGCTGG CCCTGCGGAT AGACTTCCGC 
AGTGAAGATA TCAAGAGGCT GCGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG4 ( NM_015386.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056201.2 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17980
Clone ID Related Accession (Same CDS sequence)	NM_015386.2 , NM_015386.3
Accession Version	NM_015386.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2370bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096557.1, BP282697.1, AU125729.1 and AL050101.1. This sequence is a reference standard in the RefSeqGene project. On Nov 24, 2018 this sequence version replaced NM_015386.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.118636.1, SRR1803616.277363.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000323786.10/ ENSP00000315775.5 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGACCA AGATGGCGGA CCTTGATTCG CCTCCGAAGC TGTCAGGGGT GCAGCAGCCG 
TCTGAGGGGG TGGGAGGTGG CCGCTGCTCC GAAATCTCCG CTGAGCTCAT TCGCTCCCTG 
ACAGAGCTGC AGGAGCTGGA GGCTGTATAC GAACGGCTCT GCGGCGAGGA GAAAGTGGTG 
GAGAGAGAGC TGGATGCTCT TTTGGAACAG CAAAACACCA TTGAAAGTAA GATGGTCACT 
CTCCACCGAA TGGGTCCTAA TCTGCAGCTG ATTGAGGGAG ATGCAAAGCA GCTGGCTGGA 
ATGATCACCT TTACCTGCAA CCTGGCTGAG AATGTGTCCA GCAAAGTTCG TCAGCTTGAC 
CTGGCCAAGA ACCGCCTCTA TCAGGCCATT CAGAGAGCTG ATGACATCTT GGACCTGAAG 
TTCTGCATGG ATGGAGTTCA GACTGCTTTG AGGAGTGAAG ATTATGAGCA GGCTGCAGCA 
CATACTCATC GCTACTTGTG CCTGGACAAG TCGGTCATTG AGCTCAGCCG ACAGGGCAAA 
GAGGGGAGCA TGATTGATGC CAACCTGAAA TTGCTGCAGG AAGCTGAGCA ACGTCTCAAA 
GCCATTGTGG CAGAGAAGTT TGCCATTGCC ACCAAGGAAG GTGATCTGCC CCAGGTGGAG 
CGCTTCTTCA AGATCTTCCC ACTGCTGGGT TTGCATGAGG AGGGATTAAG AAAGTTCTCG 
GAGTACCTTT GCAAGCAGGT GGCCAGTAAA GCTGAGGAGA ATCTGCTCAT GGTGCTGGGG 
ACAGACATGA GTGATCGGAG AGCTGCAGTC ATCTTTGCAG ATACACTTAC TCTTCTGTTT 
GAAGGGATTG CCCGCATTGT GGAGACCCAC CAGCCAATAG TGGAGACCTA TTATGGGCCA 
GGGAGACTCT ATACCCTGAT CAAATATCTG CAGGTGGAAT GTGACAGACA GGTGGAGAAG 
GTGGTAGACA AGTTCATCAA GCAAAGGGAC TACCACCAGC AGTTCCGGCA TGTTCAGAAC 
AACCTGATGA GAAATTCTAC AACAGAAAAA ATCGAACCAA GAGAACTGGA CCCCATCCTG 
ACTGAGGTCA CCCTGATGAA TGCCCGCAGT GAGCTATACT TACGCTTCCT CAAGAAGAGG 
ATTAGCTCTG ATTTTGAGGT GGGAGACTCC ATGGCCTCAG AGGAAGTAAA GCAAGAGCAC 
CAGAAGTGTC TGGACAAACT CCTCAATAAC TGCCTTTTGA GCTGTACCAT GCAGGAGCTA 
ATTGGCTTAT ATGTTACCAT GGAGGAGTAC TTCATGAGGG AGACTGTCAA TAAGGCTGTG 
GCTCTGGACA CCTATGAGAA GGGCCAGCTG ACATCCAGCA TGGTGGATGA TGTCTTCTAC 
ATTGTTAAGA AGTGCATTGG GCGGGCTCTG TCCAGCTCCA GCATTGACTG TCTCTGTGCC 
ATGATCAACC TCGCCACCAC AGAGCTGGAG TCTGACTTCA GGGATGTTCT GTGTAATAAG 
CTGCGGATGG GCTTTCCTGC CACCACCTTC CAGGACATCC AGCGCGGGGT GACAAGTGCC 
GTGAACATCA TGCACAGCAG CCTCCAGCAA GGCAAATTTG ACACAAAAGG CATCGAGAGT 
ACTGACGAGG CGAAGATGTC CTTCCTGGTG ACTCTGAACA ACGTGGAAGT CTGCAGTGAA 
AACATCTCCA CTCTGAAGAA GACACTGGAG AGTGACTGCA CCAAGCTCTT CAGCCAGGGC 
ATTGGAGGGG AGCAGGCCCA GGCCAAGTTT GACAGCTGCC TTTCTGACTT GGCCGCCGTG 
TCCAACAAAT TCCGAGACCT CTTGCAGGAA GGGCTGACGG AGCTCAACAG CACAGCCATC 
AAGCCACAGG TGCAGCCTTG GATCAACAGC TTTTTCTCCG TCTCCCACAA CATCGAGGAG 
GAAGAATTCA ATGACTATGA GGCCAACGAC CCTTGGGTAC AACAGTTCAT CCTTAACCTG 
GAGCAGCAAA TGGCAGAGTT CAAGGCCAGC CTGTCCCCGG TCATCTACGA CAGCCTAACC 
GGCCTCATGA CTAGCCTTGT TGCCGTCGAG TTGGAGAAAG TGGTGCTGAA ATCCACCTTT 
AACCGGCTGG GTGGTCTGCA GTTTGACAAG GAGCTGAGGT CGCTCATTGC CTACCTTACC 
ACGGTGACCA CCTGGACCAT CCGAGACAAG TTTGCCCGGC TCTCCCAGAT GGCCACCATC 
CTCAATCTGG AGCGGGTGAC CGAGATCCTC GATTACTGGG GACCCAATTC CGGCCCATTG 
ACGTGGCGCC TCACCCCTGC TGAAGTGCGC CAGGTGCTGG CCCTGCGGAT AGACTTCCGC 
AGTGAAGATA TCAAGAGGCT GCGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056201.2
CDS	12..2381
Translation	MGTKMADLDSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	NM_015386.3
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015386.3

ORF Insert Sequence:

ATGGGGACCA AGATGGCGGA CCTTGATTCG CCTCCGAAGC TGTCAGGGGT GCAGCAGCCG 
TCTGAGGGGG TGGGAGGTGG CCGCTGCTCC GAAATCTCCG CTGAGCTCAT TCGCTCCCTG 
ACAGAGCTGC AGGAGCTGGA GGCTGTATAC GAACGGCTCT GCGGCGAGGA GAAAGTGGTG 
GAGAGAGAGC TGGATGCTCT TTTGGAACAG CAAAACACCA TTGAAAGTAA GATGGTCACT 
CTCCACCGAA TGGGTCCTAA TCTGCAGCTG ATTGAGGGAG ATGCAAAGCA GCTGGCTGGA 
ATGATCACCT TTACCTGCAA CCTGGCTGAG AATGTGTCCA GCAAAGTTCG TCAGCTTGAC 
CTGGCCAAGA ACCGCCTCTA TCAGGCCATT CAGAGAGCTG ATGACATCTT GGACCTGAAG 
TTCTGCATGG ATGGAGTTCA GACTGCTTTG AGGAGTGAAG ATTATGAGCA GGCTGCAGCA 
CATACTCATC GCTACTTGTG CCTGGACAAG TCGGTCATTG AGCTCAGCCG ACAGGGCAAA 
GAGGGGAGCA TGATTGATGC CAACCTGAAA TTGCTGCAGG AAGCTGAGCA ACGTCTCAAA 
GCCATTGTGG CAGAGAAGTT TGCCATTGCC ACCAAGGAAG GTGATCTGCC CCAGGTGGAG 
CGCTTCTTCA AGATCTTCCC ACTGCTGGGT TTGCATGAGG AGGGATTAAG AAAGTTCTCG 
GAGTACCTTT GCAAGCAGGT GGCCAGTAAA GCTGAGGAGA ATCTGCTCAT GGTGCTGGGG 
ACAGACATGA GTGATCGGAG AGCTGCAGTC ATCTTTGCAG ATACACTTAC TCTTCTGTTT 
GAAGGGATTG CCCGCATTGT GGAGACCCAC CAGCCAATAG TGGAGACCTA TTATGGGCCA 
GGGAGACTCT ATACCCTGAT CAAATATCTG CAGGTGGAAT GTGACAGACA GGTGGAGAAG 
GTGGTAGACA AGTTCATCAA GCAAAGGGAC TACCACCAGC AGTTCCGGCA TGTTCAGAAC 
AACCTGATGA GAAATTCTAC AACAGAAAAA ATCGAACCAA GAGAACTGGA CCCCATCCTG 
ACTGAGGTCA CCCTGATGAA TGCCCGCAGT GAGCTATACT TACGCTTCCT CAAGAAGAGG 
ATTAGCTCTG ATTTTGAGGT GGGAGACTCC ATGGCCTCAG AGGAAGTAAA GCAAGAGCAC 
CAGAAGTGTC TGGACAAACT CCTCAATAAC TGCCTTTTGA GCTGTACCAT GCAGGAGCTA 
ATTGGCTTAT ATGTTACCAT GGAGGAGTAC TTCATGAGGG AGACTGTCAA TAAGGCTGTG 
GCTCTGGACA CCTATGAGAA GGGCCAGCTG ACATCCAGCA TGGTGGATGA TGTCTTCTAC 
ATTGTTAAGA AGTGCATTGG GCGGGCTCTG TCCAGCTCCA GCATTGACTG TCTCTGTGCC 
ATGATCAACC TCGCCACCAC AGAGCTGGAG TCTGACTTCA GGGATGTTCT GTGTAATAAG 
CTGCGGATGG GCTTTCCTGC CACCACCTTC CAGGACATCC AGCGCGGGGT GACAAGTGCC 
GTGAACATCA TGCACAGCAG CCTCCAGCAA GGCAAATTTG ACACAAAAGG CATCGAGAGT 
ACTGACGAGG CGAAGATGTC CTTCCTGGTG ACTCTGAACA ACGTGGAAGT CTGCAGTGAA 
AACATCTCCA CTCTGAAGAA GACACTGGAG AGTGACTGCA CCAAGCTCTT CAGCCAGGGC 
ATTGGAGGGG AGCAGGCCCA GGCCAAGTTT GACAGCTGCC TTTCTGACTT GGCCGCCGTG 
TCCAACAAAT TCCGAGACCT CTTGCAGGAA GGGCTGACGG AGCTCAACAG CACAGCCATC 
AAGCCACAGG TGCAGCCTTG GATCAACAGC TTTTTCTCCG TCTCCCACAA CATCGAGGAG 
GAAGAATTCA ATGACTATGA GGCCAACGAC CCTTGGGTAC AACAGTTCAT CCTTAACCTG 
GAGCAGCAAA TGGCAGAGTT CAAGGCCAGC CTGTCCCCGG TCATCTACGA CAGCCTAACC 
GGCCTCATGA CTAGCCTTGT TGCCGTCGAG TTGGAGAAAG TGGTGCTGAA ATCCACCTTT 
AACCGGCTGG GTGGTCTGCA GTTTGACAAG GAGCTGAGGT CGCTCATTGC CTACCTTACC 
ACGGTGACCA CCTGGACCAT CCGAGACAAG TTTGCCCGGC TCTCCCAGAT GGCCACCATC 
CTCAATCTGG AGCGGGTGAC CGAGATCCTC GATTACTGGG GACCCAATTC CGGCCCATTG 
ACGTGGCGCC TCACCCCTGC TGAAGTGCGC CAGGTGCTGG CCCTGCGGAT AGACTTCCGC 
AGTGAAGATA TCAAGAGGCT GCGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COG4 ( NM_001195139.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001182068.2 Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 2, mRNA.

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CloneID	OHu107929
Clone ID Related Accession (Same CDS sequence)	NM_001195139.2
Accession Version	NM_001195139.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Homo sapiens(human)
Product	conserved oligomeric Golgi complex subunit 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096557.1, BP282697.1, AU125729.1, AL050101.1 and AC106804.4. On Jan 26, 2019 this sequence version replaced NM_001195139.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.20250.1, SRR1803612.259815.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACC TTGATTCGCC TCCGAAGCTG TCAGGGGTGC AGCAGCCGTC TGAGGGGGTG 
GGAGGTGGCC GCTGCTCCGA AATCTCCGCT GAGCTCATTC GCTCCCTGAC AGAGCTGCAG 
GAGCTGGAGG CTGTATACGA ACGGCTCTGC GGCGAGGAGA AAGTGGTGGA GAGAGAGCTG 
GATGCTCTTT TGGAACAGCA AAACACCATT GAAAGTAAGA TGGTCACTCT CCACCGAATG 
GGTCCTAATC TGCAGCTGAT TGAGGGAGAT GCAAAGCAGC TGGCTGGAAT GATCACCTTT 
ACCTGCAACC TGGCTGAGAA TGTGTCCAGC AAAGTTCGTC AGCTTGACCT GGCCAAGAAC 
CGCCTCTATC AGGCCATTCA GAGAGCTGAT GACATCTTGG ACCTGAAGTT CTGCATGGAT 
GGAGTTCAGA CTGCTTTGAG GAGTGAAGAT TATGAGCAGG CTGCAGCACA TACTCATCGC 
TACTTGTGCC TGGACAAGTC GGTCATTGAG CTCAGCCGAC AGGGCAAAGA GGGGAGCATG 
ATTGATGCCA ACCTGAAATT GCTGCAGGAA GCTGAGCAAC GTCTCAAAGC CATTGTGGCA 
GAGAAGTTTG CCATTGCCAC CAAGGAAGGT GATCTGCCCC AGGTGGAGCG CTTCTTCAAG 
ATCTTCCCAC TGCTGGGTTT GCATGAGGAG GGATTAAGAA AGTTCTCGGA GTACCTTTGC 
AAGCAGGTGG CCAGTAAAGC TGAGGAGAAT CTGCTCATGG TGCTGGGGAC AGACATGAGT 
GATCGGAGAG CTGCAGTCAT CTTTGCAGAT ACACTTACTC TTCTGTTTGA AGGGATTGCC 
CGCATTGTGG AGACCCACCA GCCAATAGTG GAGACCTATT ATGGGCCAGG GAGACTCTAT 
ACCCTGATCA AATATCTGCA GGTGGAATGT GACAGACAGG TGGAGAAGGT GGTAGACAAG 
TTCATCAAGC AAAGGGACTA CCACCAGCAG TTCCGGCATG TTCAGAACAA CCTGATGAGA 
AATTCTACAA CAGAAAAAAT CGAACCAAGA GAACTGGACC CCATCCTGAC TGAGGTCACC 
CTGATGAATG CCCGCAGTGA GCTATACTTA CGCTTCCTCA AGAAGAGGAT TAGCTCTGAT 
TTTGAGGTGG GAGACTCCAT GGCCTCAGAG GAAGTAAAGC AAGAGCACCA GAAGTGTCTG 
GACAAACTCC TCAATAACTG CCTTTTGAGC TGTACCATGC AGGAGCTAAT TGGCTTATAT 
GTTACCATGG AGGAGTACTT CATGAGGGAG ACTGTCAATA AGGCTGTGGC TCTGGACACC 
TATGAGAAGG GCCAGCTGAC ATCCAGCATG GTGGATGATG TCTTCTACAT TGTTAAGAAG 
TGCATTGGGC GGGCTCTGTC CAGCTCCAGC ATTGACTGTC TCTGTGCCAT GATCAACCTC 
GCCACCACAG AGCTGGAGTC TGACTTCAGG GATGTTCTGT GTAATAAGCT GCGGATGGGC 
TTTCCTGCCA CCACCTTCCA GGACATCCAG CGCGGGGTGA CAAGTGCCGT GAACATCATG 
CACAGCAGCC TCCAGCAAGG CAAATTTGAC ACAAAAGGCA TCGAGAGTAC TGACGAGGCG 
AAGATGTCCT TCCTGAGTGA CTGCACCAAG CTCTTCAGCC AGGGCATTGG AGGGGAGCAG 
GCCCAGGCCA AGTTTGACAG CTGCCTTTCT GACTTGGCCG CCGTGTCCAA CAAATTCCGA 
GACCTCTTGC AGGAAGGGCT GACGGAGCTC AACAGCACAG CCATCAAGCC ACAGGTGCAG 
CCTTGGATCA ACAGCTTTTT CTCCGTCTCC CACAACATCG AGGAGGAAGA ATTCAATGAC 
TATGAGGCCA ACGACCCTTG GGTACAACAG TTCATCCTTA ACCTGGAGCA GCAAATGGCA 
GAGTTCAAGG CCAGCCTGTC CCCGGTCATC TACGACAGCC TAACCGGCCT CATGACTAGC 
CTTGTTGCCG TCGAGTTGGA GAAAGTGGTG CTGAAATCCA CCTTTAACCG GCTGGGTGGT 
CTGCAGTTTG ACAAGGAGCT GAGGTCGCTC ATTGCCTACC TTACCACGGT GACCACCTGG 
ACCATCCGAG ACAAGTTTGC CCGGCTCTCC CAGATGGCCA CCATCCTCAA TCTGGAGCGG 
GTGACCGAGA TCCTCGATTA CTGGGGACCC AATTCCGGCC CATTGACGTG GCGCCTCACC 
CCTGCTGAAG TGCGCCAGGT GCTGGCCCTG CGGATAGACT TCCGCAGTGA AGATATCAAG 
AGGCTGCGCC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001182068.2
CDS	24..2318
Translation	MADLDSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLSDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL

Target ORF information:

RefSeq Version	NM_001195139.2
Organism	Homo sapiens(human)
Definition	Homo sapiens component of oligomeric golgi complex 4 (COG4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001195139.2

ORF Insert Sequence:

ATGGCGGACC TTGATTCGCC TCCGAAGCTG TCAGGGGTGC AGCAGCCGTC TGAGGGGGTG 
GGAGGTGGCC GCTGCTCCGA AATCTCCGCT GAGCTCATTC GCTCCCTGAC AGAGCTGCAG 
GAGCTGGAGG CTGTATACGA ACGGCTCTGC GGCGAGGAGA AAGTGGTGGA GAGAGAGCTG 
GATGCTCTTT TGGAACAGCA AAACACCATT GAAAGTAAGA TGGTCACTCT CCACCGAATG 
GGTCCTAATC TGCAGCTGAT TGAGGGAGAT GCAAAGCAGC TGGCTGGAAT GATCACCTTT 
ACCTGCAACC TGGCTGAGAA TGTGTCCAGC AAAGTTCGTC AGCTTGACCT GGCCAAGAAC 
CGCCTCTATC AGGCCATTCA GAGAGCTGAT GACATCTTGG ACCTGAAGTT CTGCATGGAT 
GGAGTTCAGA CTGCTTTGAG GAGTGAAGAT TATGAGCAGG CTGCAGCACA TACTCATCGC 
TACTTGTGCC TGGACAAGTC GGTCATTGAG CTCAGCCGAC AGGGCAAAGA GGGGAGCATG 
ATTGATGCCA ACCTGAAATT GCTGCAGGAA GCTGAGCAAC GTCTCAAAGC CATTGTGGCA 
GAGAAGTTTG CCATTGCCAC CAAGGAAGGT GATCTGCCCC AGGTGGAGCG CTTCTTCAAG 
ATCTTCCCAC TGCTGGGTTT GCATGAGGAG GGATTAAGAA AGTTCTCGGA GTACCTTTGC 
AAGCAGGTGG CCAGTAAAGC TGAGGAGAAT CTGCTCATGG TGCTGGGGAC AGACATGAGT 
GATCGGAGAG CTGCAGTCAT CTTTGCAGAT ACACTTACTC TTCTGTTTGA AGGGATTGCC 
CGCATTGTGG AGACCCACCA GCCAATAGTG GAGACCTATT ATGGGCCAGG GAGACTCTAT 
ACCCTGATCA AATATCTGCA GGTGGAATGT GACAGACAGG TGGAGAAGGT GGTAGACAAG 
TTCATCAAGC AAAGGGACTA CCACCAGCAG TTCCGGCATG TTCAGAACAA CCTGATGAGA 
AATTCTACAA CAGAAAAAAT CGAACCAAGA GAACTGGACC CCATCCTGAC TGAGGTCACC 
CTGATGAATG CCCGCAGTGA GCTATACTTA CGCTTCCTCA AGAAGAGGAT TAGCTCTGAT 
TTTGAGGTGG GAGACTCCAT GGCCTCAGAG GAAGTAAAGC AAGAGCACCA GAAGTGTCTG 
GACAAACTCC TCAATAACTG CCTTTTGAGC TGTACCATGC AGGAGCTAAT TGGCTTATAT 
GTTACCATGG AGGAGTACTT CATGAGGGAG ACTGTCAATA AGGCTGTGGC TCTGGACACC 
TATGAGAAGG GCCAGCTGAC ATCCAGCATG GTGGATGATG TCTTCTACAT TGTTAAGAAG 
TGCATTGGGC GGGCTCTGTC CAGCTCCAGC ATTGACTGTC TCTGTGCCAT GATCAACCTC 
GCCACCACAG AGCTGGAGTC TGACTTCAGG GATGTTCTGT GTAATAAGCT GCGGATGGGC 
TTTCCTGCCA CCACCTTCCA GGACATCCAG CGCGGGGTGA CAAGTGCCGT GAACATCATG 
CACAGCAGCC TCCAGCAAGG CAAATTTGAC ACAAAAGGCA TCGAGAGTAC TGACGAGGCG 
AAGATGTCCT TCCTGAGTGA CTGCACCAAG CTCTTCAGCC AGGGCATTGG AGGGGAGCAG 
GCCCAGGCCA AGTTTGACAG CTGCCTTTCT GACTTGGCCG CCGTGTCCAA CAAATTCCGA 
GACCTCTTGC AGGAAGGGCT GACGGAGCTC AACAGCACAG CCATCAAGCC ACAGGTGCAG 
CCTTGGATCA ACAGCTTTTT CTCCGTCTCC CACAACATCG AGGAGGAAGA ATTCAATGAC 
TATGAGGCCA ACGACCCTTG GGTACAACAG TTCATCCTTA ACCTGGAGCA GCAAATGGCA 
GAGTTCAAGG CCAGCCTGTC CCCGGTCATC TACGACAGCC TAACCGGCCT CATGACTAGC 
CTTGTTGCCG TCGAGTTGGA GAAAGTGGTG CTGAAATCCA CCTTTAACCG GCTGGGTGGT 
CTGCAGTTTG ACAAGGAGCT GAGGTCGCTC ATTGCCTACC TTACCACGGT GACCACCTGG 
ACCATCCGAG ACAAGTTTGC CCGGCTCTCC CAGATGGCCA CCATCCTCAA TCTGGAGCGG 
GTGACCGAGA TCCTCGATTA CTGGGGACCC AATTCCGGCC CATTGACGTG GCGCCTCACC 
CCTGCTGAAG TGCGCCAGGT GCTGGCCCTG CGGATAGACT TCCGCAGTGA AGATATCAAG 
AGGCTGCGCC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Nature514(7520)92-97(2014 Oct)
Perry JR,Day F,Elks CE,Sulem P,Thompson DJ,Ferreira T,He C,Chasman DI,Esko T,Thorleifsson G,Albrecht E,Ang WQ,Corre T,Cousminer DL,Feenstra B,Franceschini N,Ganna A,Johnson AD,Kjellqvist S,Lunetta KL,McMahon G,Nolte IM,Paternoster L,Porcu E,Smith AV,Stolk L,Teumer A,T?ernikova N,Tikkanen E,Ulivi S,Wagner EK,Amin N,Bierut LJ,Byrne EM,Hottenga JJ,Koller DL,Mangino M,Pers TH,Yerges-Armstrong LM,Zhao JH,Andrulis IL,Anton-Culver H,Atsma F,Bandinelli S,Beckmann MW,Benitez J,Blomqvist C,Bojesen SE,Bolla MK,Bonanni B,Brauch H,Brenner H,Buring JE,Chang-Claude J,Chanock S,Chen J,Chenevix-Trench G,Coll?e JM,Couch FJ,Couper D,Coveillo AD,Cox A,Czene K,D'adamo AP,Smith GD,De Vivo I,Demerath EW,Dennis J,Devilee P,Dieffenbach AK,Dunning AM,Eiriksdottir G,Eriksson JG,Fasching PA,Ferrucci L,Flesch-Janys D,Flyger H,Foroud T,Franke L,Garcia ME,Garc?a-Closas M,Geller F,de Geus EE,Giles GG,Gudbjartsson DF,Gudnason V,Gu?nel P,Guo S,Hall P,Hamann U,Haring R,Hartman CA,Heath AC,Hofman A,Hooning MJ,Hopper JL,Hu FB,Hunter DJ,Karasik D,Kiel DP,Knight JA,Kosma VM,Kutalik Z,Lai S,Lambrechts D,Lindblom A,M?gi R,Magnusson PK,Mannermaa A,Martin NG,Masson G,McArdle PF,McArdle WL,Melbye M,Michailidou K,Mihailov E,Milani L,Milne RL,Nevanlinna H,Neven P,Nohr EA,Oldehinkel AJ,Oostra BA,Palotie A,Peacock M,Pedersen NL,Peterlongo P,Peto J,Pharoah PD,Postma DS,Pouta A,Pylk?s K,Radice P,Ring S,Rivadeneira F,Robino A,Rose LM,Rudolph A,Salomaa V,Sanna S,Schlessinger D,Schmidt MK,Southey MC,Sovio U,Stampfer MJ,St?ckl D,Storniolo AM,Timpson NJ,Tyrer J,Visser JA,Vollenweider P,V?lzke H,Waeber G,Waldenberger M,Wallaschofski H,Wang Q,Willemsen G,Winqvist R,Wolffenbuttel BH,Wright MJ,,,,,,,Boomsma DI,Econs MJ,Khaw KT,Loos RJ,McCarthy MI,Montgomery GW,Rice JP,Streeten EA,Thorsteinsdottir U,van Duijn CM,Alizadeh BZ,Bergmann S,Boerwinkle E,Boyd HA,Crisponi L,Gasparini P,Gieger C,Harris TB,Ingelsson E,J?rvelin MR,Kraft P,Lawlor D,Metspalu A,Pennell CE,Ridker PM,Snieder H,S?rensen TI,Spector TD,Strachan DP,Uitterlinden AG,Wareham NJ,Widen E,Zygmunt M,Murray A,Easton DF,Stefansson K,Murabito JM,Ong KK

Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.
Proceedings of the National Academy of Sciences of the United States of America106(32)13329-34(2009 Aug)
Richardson BC,Smith RD,Ungar D,Nakamura A,Jeffrey PD,Lupashin VV,Hughson FM

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COG4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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