FSCN2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FSCN2
Entrez Gene ID	25794
Full Name	fascin actin-bundling protein 2, retinal
Synonyms	RFSN,RP30
General protein information	Preferred Names fascin actin-bundling protein 2, retinal Names fascin-2 fascin homolog 2, actin-bundling protein, retinal
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.3
Summary	This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	607643
Disorder Html:	Retinitis pigmentosa 30, 607921 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011524587.2	XP_011522889.1	fascin-2 isoform X1
XM_011524593.1	XP_011522895.1	fascin-2 isoform X1
NM_001077182.2	NP_001070650.1	fascin-2 isoform 2
NM_012418.4	NP_036550.1	fascin-2 isoform 1
NM_012418.3	NP_036550.1	fascin-2 isoform 1
NM_001077182.3	NP_001070650.1	fascin-2 isoform 2
XM_011524590.2	XP_011522892.1	fascin-2 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FSCN2	XP_003435223.1
Rattus norvegicus (Norway rat)	Fscn2	NP_001100542.1
Drosophila melanogaster (fruit fly)	sn	NP_001162696.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012991	XP_003437121.1
Pan troglodytes (chimpanzee)	FSCN2	XP_003953273.1
Gallus gallus (chicken)	FSCN2	NP_001171209.1
Danio rerio (zebrafish)	fscn2a	NP_001116988.1
Homo sapiens (human)	FSCN2	NP_001070650.1
	FSCN2	XP_001110926.2
Mus musculus (house mouse)	Fscn2	NP_766390.2
Danio rerio (zebrafish)	fscn2b	NP_957064.2
Xenopus tropicalis (tropical clawed frog)	fscn2	NP_001093724.1
Bos taurus (cattle)	FSCN2	NP_788806.1

Gene Ontology
Bibliography

Related articles in PubMed

High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium: An immunohistochemical and clinicopathologic study.
Onder S, Taskin OC, Sen F, Topuz S, Kucucuk S, Sozen H, Ilhan R, Tuzlali S, Yavuz E
Medicine96(10)e6248(2017 Mar)

Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism.
Mohr CF, Gross C, Bros M, Reske-Kunz AB, Biesinger B, Thoma-Kress AK
Virology485481-91(2015 Nov)

Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization.
Van Audenhove I, Boucherie C, Pieters L, Zwaenepoel O, Vanloo B, Martens E, Verbrugge C, Hassanzadeh-Ghassabeh G, Vandekerckhove J, Cornelissen M, De Ganck A, Gettemans J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology28(4)1805-18(2014 Apr)

Serological investigation of the clinical significance of fascin in non-small-cell lung cancer.
Teng Y, Xu S, Yue W, Ma L, Zhang L, Zhao X, Guo Y, Zhang C, Gu M, Wang Y
Lung cancer (Amsterdam, Netherlands)82(2)346-52(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

diffuse expression in 82% of undifferentiated/dedifferentiated endometrial carcinomas
Title: High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium: An immunohistochemical and clinicopathologic study.

Tax-mediated transcriptional induction of Fascin requires NF-kappaB- and TRR-dependent promoter activation, and a promoter-independent, but PP2-sensitive signaling pathway.
Title: Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism.

Data indicate the specific contribution of fascin and cortactin during invadopodium formation.
Title: Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization.

the serum fascin level is an effective indicator of tumor aggressiveness, and that it plays an important role in the prognosis of NSCLC, particularly for non-distant metastatic patients.
Title: Serological investigation of the clinical significance of fascin in non-small-cell lung cancer.

The filopodium: a stable structure with highly regulated repetitive cycles of elongation and persistence depending on the actin cross-linker fascin
Title: The filopodium: a stable structure with highly regulated repetitive cycles of elongation and persistence depending on the actin cross-linker fascin.

The following FSCN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FSCN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22330	NM_012418.4 Latest version!	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu22529	NM_001077182.3 Latest version!	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$300.30 $429.00
OHu22330	XM_011524593.1 Latest version!	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu22529	XM_011524587.2 Latest version!	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$300.30 $429.00
OHu22529	XM_011524590.2 Latest version!	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$300.30 $429.00
View Old Accession Versions >>
OHu22330	NM_012418.3	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu22529	NM_001077182.2	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$300.30 $429.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FSCN2 ( NM_012418.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036550.1 Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22330
Clone ID Related Accession (Same CDS sequence)	XM_011524593.1 , NM_012418.4 , NM_012418.3
Accession Version	NM_012418.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	fascin-2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139149.6, AA059324.1 and AF030165.1. On Jun 2, 2019 this sequence version replaced NM_012418.3. Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 2, resulting in a shorter protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF030165.1, BC126295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGCAAG GACGAAGAGT TCACCCTCAA GCTCATCAAC 
CGGCCCATCC TGGTGCTGCG CGGCCTGGAC GGCTTCGTCT GCCACCACCG CGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CGTCTACGAC GTCTTCCACC TGAGCTTCAG CGACGGCGCC 
TACCGGATCC GAGGCCGCGA CGGAGGGTTC TGGTACACGG GCAGCCACGG CAGCGTGTGC 
AGCGACGGCG AACGCGCCGA GGACTTCGTC TTCGAGTTCC GTGAGCGCGG CCGCCTGGCC 
ATCCGCGCCC GGAGCGGCAA GTACCTGCGC GGCGGCGCCT CGGGCCTGCT GCGGGCCGAT 
GCCGACGCCC CGGCCGGGAC CGCGCTTTGG GAGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036550.1
CDS	156..1634
Translation	MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY

Target ORF information:

RefSeq Version	NM_012418.4
Organism	Homo sapiens(human)
Definition	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012418.4

ORF Insert Sequence:

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGCAAG GACGAAGAGT TCACCCTCAA GCTCATCAAC 
CGGCCCATCC TGGTGCTGCG CGGCCTGGAC GGCTTCGTCT GCCACCACCG CGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CGTCTACGAC GTCTTCCACC TGAGCTTCAG CGACGGCGCC 
TACCGGATCC GAGGCCGCGA CGGAGGGTTC TGGTACACGG GCAGCCACGG CAGCGTGTGC 
AGCGACGGCG AACGCGCCGA GGACTTCGTC TTCGAGTTCC GTGAGCGCGG CCGCCTGGCC 
ATCCGCGCCC GGAGCGGCAA GTACCTGCGC GGCGGCGCCT CGGGCCTGCT GCGGGCCGAT 
GCCGACGCCC CGGCCGGGAC CGCGCTTTGG GAGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FSCN2 ( NM_012418.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036550.1 Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22330
Clone ID Related Accession (Same CDS sequence)	XM_011524593.1 , NM_012418.4 , NM_012418.3
Accession Version	NM_012418.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	fascin-2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA059324.1, AF030165.1 and AC139149.6. On Nov 19, 2009 this sequence version replaced NM_012418.2. Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 2, resulting in a shorter protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF030165.1, BC126295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGCAAG GACGAAGAGT TCACCCTCAA GCTCATCAAC 
CGGCCCATCC TGGTGCTGCG CGGCCTGGAC GGCTTCGTCT GCCACCACCG CGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CGTCTACGAC GTCTTCCACC TGAGCTTCAG CGACGGCGCC 
TACCGGATCC GAGGCCGCGA CGGAGGGTTC TGGTACACGG GCAGCCACGG CAGCGTGTGC 
AGCGACGGCG AACGCGCCGA GGACTTCGTC TTCGAGTTCC GTGAGCGCGG CCGCCTGGCC 
ATCCGCGCCC GGAGCGGCAA GTACCTGCGC GGCGGCGCCT CGGGCCTGCT GCGGGCCGAT 
GCCGACGCCC CGGCCGGGAC CGCGCTTTGG GAGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036550.1
CDS	142..1620
Translation	MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY

Target ORF information:

RefSeq Version	NM_012418.3
Organism	Homo sapiens(human)
Definition	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012418.3

ORF Insert Sequence:

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGCAAG GACGAAGAGT TCACCCTCAA GCTCATCAAC 
CGGCCCATCC TGGTGCTGCG CGGCCTGGAC GGCTTCGTCT GCCACCACCG CGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CGTCTACGAC GTCTTCCACC TGAGCTTCAG CGACGGCGCC 
TACCGGATCC GAGGCCGCGA CGGAGGGTTC TGGTACACGG GCAGCCACGG CAGCGTGTGC 
AGCGACGGCG AACGCGCCGA GGACTTCGTC TTCGAGTTCC GTGAGCGCGG CCGCCTGGCC 
ATCCGCGCCC GGAGCGGCAA GTACCTGCGC GGCGGCGCCT CGGGCCTGCT GCGGGCCGAT 
GCCGACGCCC CGGCCGGGAC CGCGCTTTGG GAGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FSCN2 ( NM_001077182.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070650.1 Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22529
Clone ID Related Accession (Same CDS sequence)	XM_011524587.2 , NM_001077182.2 , NM_001077182.3 , XM_011524590.2
Accession Version	NM_001077182.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	fascin-2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA059324.1, AF030165.1, AC139149.6 and AI189621.1. This sequence is a reference standard in the RefSeqGene project. On Nov 19, 2009 this sequence version replaced NM_001077182.1. Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145313 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070650.1
CDS	142..1692
Translation	MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGPPPRPAWTGKVAGGAAQQTLSPPGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY

Target ORF information:

RefSeq Version	NM_001077182.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077182.2

ORF Insert Sequence:

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FSCN2 ( NM_001077182.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070650.1 Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 2, mRNA.

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CloneID	OHu22529
Clone ID Related Accession (Same CDS sequence)	XM_011524587.2 , NM_001077182.2 , NM_001077182.3 , XM_011524590.2
Accession Version	NM_001077182.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	fascin-2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC139149.6, AA059324.1, AF030165.1 and AI189621.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_001077182.2. Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145313 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070650.1
CDS	156..1706
Translation	MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGPPPRPAWTGKVAGGAAQQTLSPPGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY

Target ORF information:

RefSeq Version	NM_001077182.3
Organism	Homo sapiens(human)
Definition	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077182.3

ORF Insert Sequence:

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FSCN2 ( XM_011524593.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522895.1 Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X8, mRNA.

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CloneID	OHu22330
Clone ID Related Accession (Same CDS sequence)	XM_011524593.1 , NM_012418.4 , NM_012418.3
Accession Version	XM_011524593.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	fascin-2 isoform X1
Comment

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGCAAG GACGAAGAGT TCACCCTCAA GCTCATCAAC 
CGGCCCATCC TGGTGCTGCG CGGCCTGGAC GGCTTCGTCT GCCACCACCG CGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CGTCTACGAC GTCTTCCACC TGAGCTTCAG CGACGGCGCC 
TACCGGATCC GAGGCCGCGA CGGAGGGTTC TGGTACACGG GCAGCCACGG CAGCGTGTGC 
AGCGACGGCG AACGCGCCGA GGACTTCGTC TTCGAGTTCC GTGAGCGCGG CCGCCTGGCC 
ATCCGCGCCC GGAGCGGCAA GTACCTGCGC GGCGGCGCCT CGGGCCTGCT GCGGGCCGAT 
GCCGACGCCC CGGCCGGGAC CGCGCTTTGG GAGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011522895.1

Translation

MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY

Target ORF information:

RefSeq Version	XM_011524593.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524593.1

ORF Insert Sequence:

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGCAAG GACGAAGAGT TCACCCTCAA GCTCATCAAC 
CGGCCCATCC TGGTGCTGCG CGGCCTGGAC GGCTTCGTCT GCCACCACCG CGGCTCCAAC 
CAGCTGGACA CCAACCGCTC CGTCTACGAC GTCTTCCACC TGAGCTTCAG CGACGGCGCC 
TACCGGATCC GAGGCCGCGA CGGAGGGTTC TGGTACACGG GCAGCCACGG CAGCGTGTGC 
AGCGACGGCG AACGCGCCGA GGACTTCGTC TTCGAGTTCC GTGAGCGCGG CCGCCTGGCC 
ATCCGCGCCC GGAGCGGCAA GTACCTGCGC GGCGGCGCCT CGGGCCTGCT GCGGGCCGAT 
GCCGACGCCC CGGCCGGGAC CGCGCTTTGG GAGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FSCN2 ( XM_011524587.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522889.1 Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X2, mRNA.

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CloneID	OHu22529
Clone ID Related Accession (Same CDS sequence)	XM_011524587.2 , NM_001077182.2 , NM_001077182.3 , XM_011524590.2
Accession Version	XM_011524587.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fascin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524587.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522889.1
CDS	1625..3175
Translation	MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGPPPRPAWTGKVAGGAAQQTLSPPGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY

Target ORF information:

RefSeq Version	XM_011524587.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524587.2

ORF Insert Sequence:

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FSCN2 ( XM_011524590.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522892.1 Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X1, mRNA.

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CloneID	OHu22529
Clone ID Related Accession (Same CDS sequence)	XM_011524587.2 , NM_001077182.2 , NM_001077182.3 , XM_011524590.2
Accession Version	XM_011524590.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fascin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524590.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522892.1
CDS	4074..5624
Translation	MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGPPPRPAWTGKVAGGAAQQTLSPPGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY

Target ORF information:

RefSeq Version	XM_011524590.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fascin actin-bundling protein 2, retinal (FSCN2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524590.2

ORF Insert Sequence:

ATGCCGACGA ACGGCCTGCA CCAGGTGCTG AAGATCCAGT TTGGCCTCGT CAACGACACT 
GACCGCTACC TGACAGCTGA GAGCTTCGGC TTCAAGGTCA ATGCCTCGGC ACCCAGCCTC 
AAGAGGAAGC AGACCTGGGT GCTGGAACCC GACCCAGGAC AAGGCACGGC TGTGCTGCTC 
CGCAGCAGCC ACCTGGGCCG CTACCTGTCG GCAGAAGAGG ACGGGCGCGT GGCCTGTGAG 
GCAGAGCAGC CGGGCCGTGA CTGCCGCTTC CTGGTCCTGC CGCAGCCAGA TGGGCGCTGG 
GTGCTGCGGT CCGAGCCGCA CGGCCGCTTC TTCGGAGGCA CCGAGGACCA GCTGTCCTGC 
TTCGCCACAG CCGTTTCCCC GGCCGAGCTG TGGACCGTGC ACCTGGCCAT CCACCCGCAG 
GCCCACCTGC TGAGCGTGAG CCGGCGGCGC TACGTGCACC TGTGCCCGCG GGAGGACGAG 
ATGGCCGCAG ACGGAGACAA GCCCTGGGGC GTGGACGCCC TCCTCACCCT CATCTTCCGG 
AGCCGACGGT ACTGCCTCAA GTCCTGTGAC AGCCGCTACC TGCGCAGCGA CGGCCGTCTG 
GTCTGGGAGC CTGAGCCCCG TGCCTGCTAC ACGCTGGAGT TCAAGGCGGG CAAGCTGGCC 
TTCAAGGACT GCGACGGCCA CTACCTGGCA CCCGTGGGGC CCGCAGGCAC CCTCAAGGCC 
GGCCGAAACA CGCGACCTGG CAAGGATGAG CTCTTTGATC TGGAGGAGAG TCACCCACAG 
GTGGTGCTGG TGGCTGCCAA CCACCGCTAC GTCTCTGTGC GGCAAGGGGT CAACGTCTCA 
GCCAATCAGG ATGATGAACT AGACCACGAG ACCTTCCTGA TGCAAATTGA CCAGGAGACA 
AAGAAGTGCA CCTTCTATTC CAGCACTGGG GGCTACTGGA CCCTGGTCAC CCATGGGGGC 
ATTCACGCCA CAGCCACACA AGTTTCTGCC AACACCATGT TTGAGATGGA GTGGCGTGGC 
CGGCGGGTAG CACTCAAAGC CAGCAACGGG CGCTACGTGT GCATGAAGAA GAATGGGCAG 
CTGGCGGCTA TCAGCGATTT TGTCGGGCCC CCACCCCGCC CGGCCTGGAC AGGGAAGGTG 
GCGGGAGGGG CAGCGCAGCA GACGCTCTCC CCGCCAGGCA AGGACGAAGA GTTCACCCTC 
AAGCTCATCA ACCGGCCCAT CCTGGTGCTG CGCGGCCTGG ACGGCTTCGT CTGCCACCAC 
CGCGGCTCCA ACCAGCTGGA CACCAACCGC TCCGTCTACG ACGTCTTCCA CCTGAGCTTC 
AGCGACGGCG CCTACCGGAT CCGAGGCCGC GACGGAGGGT TCTGGTACAC GGGCAGCCAC 
GGCAGCGTGT GCAGCGACGG CGAACGCGCC GAGGACTTCG TCTTCGAGTT CCGTGAGCGC 
GGCCGCCTGG CCATCCGCGC CCGGAGCGGC AAGTACCTGC GCGGCGGCGC CTCGGGCCTG 
CTGCGGGCCG ATGCCGACGC CCCGGCCGGG ACCGCGCTTT GGGAGTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium: An immunohistochemical and clinicopathologic study.
Medicine96(10)e6248(2017 Mar)
Onder S,Taskin OC,Sen F,Topuz S,Kucucuk S,Sozen H,Ilhan R,Tuzlali S,Yavuz E

Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism.
Virology485481-91(2015 Nov)
Mohr CF,Gross C,Bros M,Reske-Kunz AB,Biesinger B,Thoma-Kress AK

Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology28(4)1805-18(2014 Apr)
Van Audenhove I,Boucherie C,Pieters L,Zwaenepoel O,Vanloo B,Martens E,Verbrugge C,Hassanzadeh-Ghassabeh G,Vandekerckhove J,Cornelissen M,De Ganck A,Gettemans J

Serological investigation of the clinical significance of fascin in non-small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands)82(2)346-52(2013 Nov)
Teng Y,Xu S,Yue W,Ma L,Zhang L,Zhao X,Guo Y,Zhang C,Gu M,Wang Y

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FSCN2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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