FBXO7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FBXO7
Entrez Gene ID	25793
Full Name	F-box protein 7
Synonyms	FBX,FBX07,FBX7,PARK15,PKPS
General protein information	Preferred Names F-box protein 7 Names F-box only protein 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q12.3
Summary	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	605648
Disorder Html:	Parkinson disease 15, autosomal recessive, 260300 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_012179.3	NP_036311.3	F-box only protein 7 isoform 1
NM_001033024.1	NP_001028196.1	F-box only protein 7 isoform 2
XM_024452207.1	XP_024307975.1	F-box only protein 7 isoform X1
NM_012179.4	NP_036311.3	F-box only protein 7 isoform 1
NM_001257990.1	NP_001244919.1	F-box only protein 7 isoform 3
XM_011530106.1	XP_011528408.1	F-box only protein 7 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Fbxo7	NP_694875.2
Homo sapiens (human)	FBXO7	NP_036311.3
	FBXO7	XP_001112612.1
Gallus gallus (chicken)	FBXO7	NP_001012555.2
Danio rerio (zebrafish)	fbxo7	NP_001020670.1
Xenopus tropicalis (tropical clawed frog)	fbxo7	NP_001072570.1
Bos taurus (cattle)	FBXO7	NP_001033148.1
Rattus norvegicus (Norway rat)	Fbxo7	NP_001012222.1
Pan troglodytes (chimpanzee)	FBXO7	XP_001153721.2
Canis lupus familiaris (dog)	FBXO7	XP_531752.4

Gene Ontology
Bibliography

Related articles in PubMed

Mechanistic contributions of FBXO7 to Parkinson disease.
Joseph S, Schulz JB, Stegm?ller J
Journal of neurochemistry144(2)118-127(2018 Jan)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

A High-Density Map for Navigating the Human Polycomb Complexome.
Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C
Cell reports17(2)583-595(2016 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Fbxo7 deficiency is associated with reduced cellular NAD(+) levels, which results in increased mitochondrial NADH redox index and impaired activity of complex I in the electron transport chain.
Title: Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation.

Structure and function of Fbxo7 in Parkinson's disease has been summarized. (Review)
Title: Structure and Function of Fbxo7/PARK15 in Parkinson's Disease.

Gsk3beta and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease
Title: Gsk3? and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.

Mutations in the F-box only protein 7 (FBXO7) gene, located on chromosome 22q12-q13, have been identified as having distinct clinical features in patients with hereditary Parkinson's disease (PD).
Title: FBXO7 mutations in Parkinson's disease and multiple system atrophy.

The mutations of F-box protein 7 (FBXO7) gene (T22M, R378G and R498X) are associated with autosomal recessive juvenile-onset Parkinson's disease We demonstrated wild-type FBXO7 is a stress response protein with both cytoprotective and neurotoxic roles
Title: F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy.

The following FBXO7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FBXO7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19211	NM_012179.4 Latest version!	Homo sapiens F-box protein 7 (FBXO7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu16168	NM_001033024.1 Latest version!	Homo sapiens F-box protein 7 (FBXO7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu21498	NM_001257990.1 Latest version!	Homo sapiens F-box protein 7 (FBXO7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21498	XM_024452207.1 Latest version!	Homo sapiens F-box protein 7 (FBXO7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu66494	XM_011530106.1 Latest version!	Homo sapiens F-box protein 7 (FBXO7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu19211	NM_012179.3	Homo sapiens F-box protein 7 (FBXO7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FBXO7 ( NM_012179.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036311.3 Homo sapiens F-box protein 7 (FBXO7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19211
Clone ID Related Accession (Same CDS sequence)	NM_012179.3 , NM_012179.4
Accession Version	NM_012179.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	F-box only protein 7 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX362053.2 and AL050254.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_012179.3. Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC008361.1, AK226087.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000266087.12/ ENSP00000266087.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGCTGC GGGTGCGGCT TCTGAAGCGG ACCTGGCCGC TGGAGGTGCC CGAGACGGAG 
CCGACGCTGG GGCATTTGCG CTCGCACCTG AGGCAGTCCC TGCTGTGCAC CTGGGGGTAC 
AGTTCTAATA CCCGATTTAC AATTACATTG AACTACAAGG ATCCCCTCAC TGGAGATGAA 
GAGACCTTGG CTTCATATGG GATTGTTTCT GGGGACTTGA TATGTTTGAT TCTTCAAGAT 
GACATTCCAG CGCCTAATAT ACCTTCATCC ACAGATTCAG AGCATTCTTC ACTCCAGAAT 
AATGAGCAAC CCTCTTTGGC CACCAGCTCC AATCAGACTA GCATGCAGGA TGAACAACCA 
AGTGATTCAT TCCAAGGACA GGCAGCCCAG TCTGGTGTTT GGAATGACGA CAGTATGTTA 
GGGCCTAGTC AAAATTTTGA AGCTGAGTCA ATTCAAGATA ATGCGCATAT GGCAGAGGGC 
ACAGGTTTCT ATCCCTCAGA ACCCATGCTC TGTAGTGAAT CGGTGGAAGG GCAAGTGCCA 
CATTCATTAG AGACCTTGTA TCAATCAGCT GACTGTTCTG ATGCCAATGA TGCCTTGATA 
GTGTTGATAC ATCTTCTCAT GTTGGAGTCA GGTTACATAC CTCAGGGCAC CGAAGCCAAA 
GCACTGTCCA TGCCGGAGAA GTGGAAGTTG AGCGGGGTGT ATAAGCTGCA GTACATGCAT 
CCTCTCTGCG AGGGCAGCTC CGCTACTCTC ACCTGTGTGC CTTTGGGAAA CCTGATTGTT 
GTAAATGCTA CACTAAAAAT CAACAATGAG ATTAGAAGTG TGAAAAGATT GCAGCTGCTA 
CCAGAATCTT TTATTTGCAA AGAGAAACTA GGGGAAAATG TAGCCAACAT ATACAAAGAT 
CTTCAGAAAC TCTCTCGCCT CTTTAAAGAC CAGCTGGTGT ATCCTCTTCT GGCTTTTACC 
CGACAAGCAC TGAACCTACC AGATGTATTT GGGTTGGTCG TCCTCCCATT GGAACTGAAA 
CTACGGATCT TCCGACTTCT GGATGTTCGT TCCGTCTTGT CTTTGTCTGC GGTTTGTCGT 
GACCTCTTTA CTGCTTCAAA TGACCCACTC CTGTGGAGGT TTTTATATCT GCGTGATTTT 
CGAGACAATA CTGTCAGAGT TCAAGACACA GATTGGAAAG AACTGTACAG GAAGAGGCAC 
ATACAAAGAA AAGAATCCCC GAAAGGGCGG TTTGTGATGC TCCTGCCATC GTCAACTCAC 
ACCATTCCAT TCTATCCCAA CCCCTTGCAC CCTAGGCCAT TTCCTAGCTC CCGCCTTCCT 
CCAGGAATTA TCGGGGGTGA ATATGACCAA AGACCAACAC TTCCCTATGT TGGAGACCCA 
ATCAGTTCAC TCATTCCTGG TCCTGGGGAG ACGCCCAGCC AGTTTCCTCC ACTGAGACCA 
CGCTTTGATC CAGTTGGCCC ACTTCCAGGA CCTAACCCCA TCTTGCCAGG GCGAGGCGGC 
CCCAATGACA GATTTCCCTT TAGACCCAGC AGGGGTCGGC CAACTGATGG CCGGCTGTCA 
TTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036311.3
CDS	193..1761
Translation	MRLRVRLLKRTWPLEVPETEPTLGHLRSHLRQSLLCTWGYSSNTRFTITLNYKDPLTGDEETLASYGIVSGDLICLILQDDIPAPNIPSSTDSEHSSLQNNEQPSLATSSNQTSMQDEQPSDSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM

Target ORF information:

RefSeq Version	NM_012179.4
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 7 (FBXO7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012179.4

ORF Insert Sequence:

ATGAGGCTGC GGGTGCGGCT TCTGAAGCGG ACCTGGCCGC TGGAGGTGCC CGAGACGGAG 
CCGACGCTGG GGCATTTGCG CTCGCACCTG AGGCAGTCCC TGCTGTGCAC CTGGGGGTAC 
AGTTCTAATA CCCGATTTAC AATTACATTG AACTACAAGG ATCCCCTCAC TGGAGATGAA 
GAGACCTTGG CTTCATATGG GATTGTTTCT GGGGACTTGA TATGTTTGAT TCTTCAAGAT 
GACATTCCAG CGCCTAATAT ACCTTCATCC ACAGATTCAG AGCATTCTTC ACTCCAGAAT 
AATGAGCAAC CCTCTTTGGC CACCAGCTCC AATCAGACTA GCATGCAGGA TGAACAACCA 
AGTGATTCAT TCCAAGGACA GGCAGCCCAG TCTGGTGTTT GGAATGACGA CAGTATGTTA 
GGGCCTAGTC AAAATTTTGA AGCTGAGTCA ATTCAAGATA ATGCGCATAT GGCAGAGGGC 
ACAGGTTTCT ATCCCTCAGA ACCCATGCTC TGTAGTGAAT CGGTGGAAGG GCAAGTGCCA 
CATTCATTAG AGACCTTGTA TCAATCAGCT GACTGTTCTG ATGCCAATGA TGCCTTGATA 
GTGTTGATAC ATCTTCTCAT GTTGGAGTCA GGTTACATAC CTCAGGGCAC CGAAGCCAAA 
GCACTGTCCA TGCCGGAGAA GTGGAAGTTG AGCGGGGTGT ATAAGCTGCA GTACATGCAT 
CCTCTCTGCG AGGGCAGCTC CGCTACTCTC ACCTGTGTGC CTTTGGGAAA CCTGATTGTT 
GTAAATGCTA CACTAAAAAT CAACAATGAG ATTAGAAGTG TGAAAAGATT GCAGCTGCTA 
CCAGAATCTT TTATTTGCAA AGAGAAACTA GGGGAAAATG TAGCCAACAT ATACAAAGAT 
CTTCAGAAAC TCTCTCGCCT CTTTAAAGAC CAGCTGGTGT ATCCTCTTCT GGCTTTTACC 
CGACAAGCAC TGAACCTACC AGATGTATTT GGGTTGGTCG TCCTCCCATT GGAACTGAAA 
CTACGGATCT TCCGACTTCT GGATGTTCGT TCCGTCTTGT CTTTGTCTGC GGTTTGTCGT 
GACCTCTTTA CTGCTTCAAA TGACCCACTC CTGTGGAGGT TTTTATATCT GCGTGATTTT 
CGAGACAATA CTGTCAGAGT TCAAGACACA GATTGGAAAG AACTGTACAG GAAGAGGCAC 
ATACAAAGAA AAGAATCCCC GAAAGGGCGG TTTGTGATGC TCCTGCCATC GTCAACTCAC 
ACCATTCCAT TCTATCCCAA CCCCTTGCAC CCTAGGCCAT TTCCTAGCTC CCGCCTTCCT 
CCAGGAATTA TCGGGGGTGA ATATGACCAA AGACCAACAC TTCCCTATGT TGGAGACCCA 
ATCAGTTCAC TCATTCCTGG TCCTGGGGAG ACGCCCAGCC AGTTTCCTCC ACTGAGACCA 
CGCTTTGATC CAGTTGGCCC ACTTCCAGGA CCTAACCCCA TCTTGCCAGG GCGAGGCGGC 
CCCAATGACA GATTTCCCTT TAGACCCAGC AGGGGTCGGC CAACTGATGG CCGGCTGTCA 
TTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO7 ( NM_001033024.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001028196.1 Homo sapiens F-box protein 7 (FBXO7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16168
Clone ID Related Accession (Same CDS sequence)	NM_001033024.1
Accession Version	NM_001033024.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	F-box only protein 7 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI821903.1, BQ326686.1, BX409547.2 and AL050254.1. Transcript Variant: This variant (2) contains a different 5' UTR and 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2) with a distinct N- terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.211647.1, SRR1163655.490295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCGGC CTCCCGGGGG CTCTGGTCCC CTCCTCGATT CAGAGCATTC TTCACTCCAG 
AATAATGAGC AACCCTCTTT GGCCACCAGC TCCAATCAGA CTAGCATGCA GGATGAACAA 
CCAAGTGATT CATTCCAAGG ACAGGCAGCC CAGTCTGGTG TTTGGAATGA CGACAGTATG 
TTAGGGCCTA GTCAAAATTT TGAAGCTGAG TCAATTCAAG ATAATGCGCA TATGGCAGAG 
GGCACAGGTT TCTATCCCTC AGAACCCATG CTCTGTAGTG AATCGGTGGA AGGGCAAGTG 
CCACATTCAT TAGAGACCTT GTATCAATCA GCTGACTGTT CTGATGCCAA TGATGCCTTG 
ATAGTGTTGA TACATCTTCT CATGTTGGAG TCAGGTTACA TACCTCAGGG CACCGAAGCC 
AAAGCACTGT CCATGCCGGA GAAGTGGAAG TTGAGCGGGG TGTATAAGCT GCAGTACATG 
CATCCTCTCT GCGAGGGCAG CTCCGCTACT CTCACCTGTG TGCCTTTGGG AAACCTGATT 
GTTGTAAATG CTACACTAAA AATCAACAAT GAGATTAGAA GTGTGAAAAG ATTGCAGCTG 
CTACCAGAAT CTTTTATTTG CAAAGAGAAA CTAGGGGAAA ATGTAGCCAA CATATACAAA 
GATCTTCAGA AACTCTCTCG CCTCTTTAAA GACCAGCTGG TGTATCCTCT TCTGGCTTTT 
ACCCGACAAG CACTGAACCT ACCAGATGTA TTTGGGTTGG TCGTCCTCCC ATTGGAACTG 
AAACTACGGA TCTTCCGACT TCTGGATGTT CGTTCCGTCT TGTCTTTGTC TGCGGTTTGT 
CGTGACCTCT TTACTGCTTC AAATGACCCA CTCCTGTGGA GGTTTTTATA TCTGCGTGAT 
TTTCGAGACA ATACTGTCAG AGTTCAAGAC ACAGATTGGA AAGAACTGTA CAGGAAGAGG 
CACATACAAA GAAAAGAATC CCCGAAAGGG CGGTTTGTGA TGCTCCTGCC ATCGTCAACT 
CACACCATTC CATTCTATCC CAACCCCTTG CACCCTAGGC CATTTCCTAG CTCCCGCCTT 
CCTCCAGGAA TTATCGGGGG TGAATATGAC CAAAGACCAA CACTTCCCTA TGTTGGAGAC 
CCAATCAGTT CACTCATTCC TGGTCCTGGG GAGACGCCCA GCCAGTTTCC TCCACTGAGA 
CCACGCTTTG ATCCAGTTGG CCCACTTCCA GGACCTAACC CCATCTTGCC AGGGCGAGGC 
GGCCCCAATG ACAGATTTCC CTTTAGACCC AGCAGGGGTC GGCCAACTGA TGGCCGGCTG 
TCATTCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028196.1
CDS	126..1457
Translation	MARPPGGSGPLLDSEHSSLQNNEQPSLATSSNQTSMQDEQPSDSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM

Target ORF information:

RefSeq Version	NM_001033024.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 7 (FBXO7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033024.1

ORF Insert Sequence:

ATGGCCCGGC CTCCCGGGGG CTCTGGTCCC CTCCTCGATT CAGAGCATTC TTCACTCCAG 
AATAATGAGC AACCCTCTTT GGCCACCAGC TCCAATCAGA CTAGCATGCA GGATGAACAA 
CCAAGTGATT CATTCCAAGG ACAGGCAGCC CAGTCTGGTG TTTGGAATGA CGACAGTATG 
TTAGGGCCTA GTCAAAATTT TGAAGCTGAG TCAATTCAAG ATAATGCGCA TATGGCAGAG 
GGCACAGGTT TCTATCCCTC AGAACCCATG CTCTGTAGTG AATCGGTGGA AGGGCAAGTG 
CCACATTCAT TAGAGACCTT GTATCAATCA GCTGACTGTT CTGATGCCAA TGATGCCTTG 
ATAGTGTTGA TACATCTTCT CATGTTGGAG TCAGGTTACA TACCTCAGGG CACCGAAGCC 
AAAGCACTGT CCATGCCGGA GAAGTGGAAG TTGAGCGGGG TGTATAAGCT GCAGTACATG 
CATCCTCTCT GCGAGGGCAG CTCCGCTACT CTCACCTGTG TGCCTTTGGG AAACCTGATT 
GTTGTAAATG CTACACTAAA AATCAACAAT GAGATTAGAA GTGTGAAAAG ATTGCAGCTG 
CTACCAGAAT CTTTTATTTG CAAAGAGAAA CTAGGGGAAA ATGTAGCCAA CATATACAAA 
GATCTTCAGA AACTCTCTCG CCTCTTTAAA GACCAGCTGG TGTATCCTCT TCTGGCTTTT 
ACCCGACAAG CACTGAACCT ACCAGATGTA TTTGGGTTGG TCGTCCTCCC ATTGGAACTG 
AAACTACGGA TCTTCCGACT TCTGGATGTT CGTTCCGTCT TGTCTTTGTC TGCGGTTTGT 
CGTGACCTCT TTACTGCTTC AAATGACCCA CTCCTGTGGA GGTTTTTATA TCTGCGTGAT 
TTTCGAGACA ATACTGTCAG AGTTCAAGAC ACAGATTGGA AAGAACTGTA CAGGAAGAGG 
CACATACAAA GAAAAGAATC CCCGAAAGGG CGGTTTGTGA TGCTCCTGCC ATCGTCAACT 
CACACCATTC CATTCTATCC CAACCCCTTG CACCCTAGGC CATTTCCTAG CTCCCGCCTT 
CCTCCAGGAA TTATCGGGGG TGAATATGAC CAAAGACCAA CACTTCCCTA TGTTGGAGAC 
CCAATCAGTT CACTCATTCC TGGTCCTGGG GAGACGCCCA GCCAGTTTCC TCCACTGAGA 
CCACGCTTTG ATCCAGTTGG CCCACTTCCA GGACCTAACC CCATCTTGCC AGGGCGAGGC 
GGCCCCAATG ACAGATTTCC CTTTAGACCC AGCAGGGGTC GGCCAACTGA TGGCCGGCTG 
TCATTCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO7 ( NM_012179.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036311.3 Homo sapiens F-box protein 7 (FBXO7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19211
Clone ID Related Accession (Same CDS sequence)	NM_012179.3 , NM_012179.4
Accession Version	NM_012179.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	F-box only protein 7 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU584368.1, BX362053.2 and AL050254.1. This sequence is a reference standard in the RefSeqGene project. On Sep 7, 2005 this sequence version replaced NM_012179.2. Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL050254.1, SRR1803615.94401.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTGC GGGTGCGGCT TCTGAAGCGG ACCTGGCCGC TGGAGGTGCC CGAGACGGAG 
CCGACGCTGG GGCATTTGCG CTCGCACCTG AGGCAGTCCC TGCTGTGCAC CTGGGGGTAC 
AGTTCTAATA CCCGATTTAC AATTACATTG AACTACAAGG ATCCCCTCAC TGGAGATGAA 
GAGACCTTGG CTTCATATGG GATTGTTTCT GGGGACTTGA TATGTTTGAT TCTTCAAGAT 
GACATTCCAG CGCCTAATAT ACCTTCATCC ACAGATTCAG AGCATTCTTC ACTCCAGAAT 
AATGAGCAAC CCTCTTTGGC CACCAGCTCC AATCAGACTA GCATGCAGGA TGAACAACCA 
AGTGATTCAT TCCAAGGACA GGCAGCCCAG TCTGGTGTTT GGAATGACGA CAGTATGTTA 
GGGCCTAGTC AAAATTTTGA AGCTGAGTCA ATTCAAGATA ATGCGCATAT GGCAGAGGGC 
ACAGGTTTCT ATCCCTCAGA ACCCATGCTC TGTAGTGAAT CGGTGGAAGG GCAAGTGCCA 
CATTCATTAG AGACCTTGTA TCAATCAGCT GACTGTTCTG ATGCCAATGA TGCCTTGATA 
GTGTTGATAC ATCTTCTCAT GTTGGAGTCA GGTTACATAC CTCAGGGCAC CGAAGCCAAA 
GCACTGTCCA TGCCGGAGAA GTGGAAGTTG AGCGGGGTGT ATAAGCTGCA GTACATGCAT 
CCTCTCTGCG AGGGCAGCTC CGCTACTCTC ACCTGTGTGC CTTTGGGAAA CCTGATTGTT 
GTAAATGCTA CACTAAAAAT CAACAATGAG ATTAGAAGTG TGAAAAGATT GCAGCTGCTA 
CCAGAATCTT TTATTTGCAA AGAGAAACTA GGGGAAAATG TAGCCAACAT ATACAAAGAT 
CTTCAGAAAC TCTCTCGCCT CTTTAAAGAC CAGCTGGTGT ATCCTCTTCT GGCTTTTACC 
CGACAAGCAC TGAACCTACC AGATGTATTT GGGTTGGTCG TCCTCCCATT GGAACTGAAA 
CTACGGATCT TCCGACTTCT GGATGTTCGT TCCGTCTTGT CTTTGTCTGC GGTTTGTCGT 
GACCTCTTTA CTGCTTCAAA TGACCCACTC CTGTGGAGGT TTTTATATCT GCGTGATTTT 
CGAGACAATA CTGTCAGAGT TCAAGACACA GATTGGAAAG AACTGTACAG GAAGAGGCAC 
ATACAAAGAA AAGAATCCCC GAAAGGGCGG TTTGTGATGC TCCTGCCATC GTCAACTCAC 
ACCATTCCAT TCTATCCCAA CCCCTTGCAC CCTAGGCCAT TTCCTAGCTC CCGCCTTCCT 
CCAGGAATTA TCGGGGGTGA ATATGACCAA AGACCAACAC TTCCCTATGT TGGAGACCCA 
ATCAGTTCAC TCATTCCTGG TCCTGGGGAG ACGCCCAGCC AGTTTCCTCC ACTGAGACCA 
CGCTTTGATC CAGTTGGCCC ACTTCCAGGA CCTAACCCCA TCTTGCCAGG GCGAGGCGGC 
CCCAATGACA GATTTCCCTT TAGACCCAGC AGGGGTCGGC CAACTGATGG CCGGCTGTCA 
TTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036311.3
CDS	284..1852
Translation	MRLRVRLLKRTWPLEVPETEPTLGHLRSHLRQSLLCTWGYSSNTRFTITLNYKDPLTGDEETLASYGIVSGDLICLILQDDIPAPNIPSSTDSEHSSLQNNEQPSLATSSNQTSMQDEQPSDSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM

Target ORF information:

RefSeq Version	NM_012179.3
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 7 (FBXO7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012179.3

ORF Insert Sequence:

ATGAGGCTGC GGGTGCGGCT TCTGAAGCGG ACCTGGCCGC TGGAGGTGCC CGAGACGGAG 
CCGACGCTGG GGCATTTGCG CTCGCACCTG AGGCAGTCCC TGCTGTGCAC CTGGGGGTAC 
AGTTCTAATA CCCGATTTAC AATTACATTG AACTACAAGG ATCCCCTCAC TGGAGATGAA 
GAGACCTTGG CTTCATATGG GATTGTTTCT GGGGACTTGA TATGTTTGAT TCTTCAAGAT 
GACATTCCAG CGCCTAATAT ACCTTCATCC ACAGATTCAG AGCATTCTTC ACTCCAGAAT 
AATGAGCAAC CCTCTTTGGC CACCAGCTCC AATCAGACTA GCATGCAGGA TGAACAACCA 
AGTGATTCAT TCCAAGGACA GGCAGCCCAG TCTGGTGTTT GGAATGACGA CAGTATGTTA 
GGGCCTAGTC AAAATTTTGA AGCTGAGTCA ATTCAAGATA ATGCGCATAT GGCAGAGGGC 
ACAGGTTTCT ATCCCTCAGA ACCCATGCTC TGTAGTGAAT CGGTGGAAGG GCAAGTGCCA 
CATTCATTAG AGACCTTGTA TCAATCAGCT GACTGTTCTG ATGCCAATGA TGCCTTGATA 
GTGTTGATAC ATCTTCTCAT GTTGGAGTCA GGTTACATAC CTCAGGGCAC CGAAGCCAAA 
GCACTGTCCA TGCCGGAGAA GTGGAAGTTG AGCGGGGTGT ATAAGCTGCA GTACATGCAT 
CCTCTCTGCG AGGGCAGCTC CGCTACTCTC ACCTGTGTGC CTTTGGGAAA CCTGATTGTT 
GTAAATGCTA CACTAAAAAT CAACAATGAG ATTAGAAGTG TGAAAAGATT GCAGCTGCTA 
CCAGAATCTT TTATTTGCAA AGAGAAACTA GGGGAAAATG TAGCCAACAT ATACAAAGAT 
CTTCAGAAAC TCTCTCGCCT CTTTAAAGAC CAGCTGGTGT ATCCTCTTCT GGCTTTTACC 
CGACAAGCAC TGAACCTACC AGATGTATTT GGGTTGGTCG TCCTCCCATT GGAACTGAAA 
CTACGGATCT TCCGACTTCT GGATGTTCGT TCCGTCTTGT CTTTGTCTGC GGTTTGTCGT 
GACCTCTTTA CTGCTTCAAA TGACCCACTC CTGTGGAGGT TTTTATATCT GCGTGATTTT 
CGAGACAATA CTGTCAGAGT TCAAGACACA GATTGGAAAG AACTGTACAG GAAGAGGCAC 
ATACAAAGAA AAGAATCCCC GAAAGGGCGG TTTGTGATGC TCCTGCCATC GTCAACTCAC 
ACCATTCCAT TCTATCCCAA CCCCTTGCAC CCTAGGCCAT TTCCTAGCTC CCGCCTTCCT 
CCAGGAATTA TCGGGGGTGA ATATGACCAA AGACCAACAC TTCCCTATGT TGGAGACCCA 
ATCAGTTCAC TCATTCCTGG TCCTGGGGAG ACGCCCAGCC AGTTTCCTCC ACTGAGACCA 
CGCTTTGATC CAGTTGGCCC ACTTCCAGGA CCTAACCCCA TCTTGCCAGG GCGAGGCGGC 
CCCAATGACA GATTTCCCTT TAGACCCAGC AGGGGTCGGC CAACTGATGG CCGGCTGTCA 
TTCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO7 ( NM_001257990.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244919.1 Homo sapiens F-box protein 7 (FBXO7), transcript variant 3, mRNA.

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CloneID	OHu21498
Clone ID Related Accession (Same CDS sequence)	XM_024452207.1 , NM_001257990.1
Accession Version	NM_001257990.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	F-box only protein 7 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI821903.1, AK301716.1, AL021937.1 and AL050254.1. Transcript Variant: This variant (3) has an alternate exon in place of the first exon compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.95969.1, SRR1803614.95505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGGATG AACAACCAAG TGATTCATTC CAAGGACAGG CAGCCCAGTC TGGTGTTTGG 
AATGACGACA GTATGTTAGG GCCTAGTCAA AATTTTGAAG CTGAGTCAAT TCAAGATAAT 
GCGCATATGG CAGAGGGCAC AGGTTTCTAT CCCTCAGAAC CCATGCTCTG TAGTGAATCG 
GTGGAAGGGC AAGTGCCACA TTCATTAGAG ACCTTGTATC AATCAGCTGA CTGTTCTGAT 
GCCAATGATG CCTTGATAGT GTTGATACAT CTTCTCATGT TGGAGTCAGG TTACATACCT 
CAGGGCACCG AAGCCAAAGC ACTGTCCATG CCGGAGAAGT GGAAGTTGAG CGGGGTGTAT 
AAGCTGCAGT ACATGCATCC TCTCTGCGAG GGCAGCTCCG CTACTCTCAC CTGTGTGCCT 
TTGGGAAACC TGATTGTTGT AAATGCTACA CTAAAAATCA ACAATGAGAT TAGAAGTGTG 
AAAAGATTGC AGCTGCTACC AGAATCTTTT ATTTGCAAAG AGAAACTAGG GGAAAATGTA 
GCCAACATAT ACAAAGATCT TCAGAAACTC TCTCGCCTCT TTAAAGACCA GCTGGTGTAT 
CCTCTTCTGG CTTTTACCCG ACAAGCACTG AACCTACCAG ATGTATTTGG GTTGGTCGTC 
CTCCCATTGG AACTGAAACT ACGGATCTTC CGACTTCTGG ATGTTCGTTC CGTCTTGTCT 
TTGTCTGCGG TTTGTCGTGA CCTCTTTACT GCTTCAAATG ACCCACTCCT GTGGAGGTTT 
TTATATCTGC GTGATTTTCG AGACAATACT GTCAGAGTTC AAGACACAGA TTGGAAAGAA 
CTGTACAGGA AGAGGCACAT ACAAAGAAAA GAATCCCCGA AAGGGCGGTT TGTGATGCTC 
CTGCCATCGT CAACTCACAC CATTCCATTC TATCCCAACC CCTTGCACCC TAGGCCATTT 
CCTAGCTCCC GCCTTCCTCC AGGAATTATC GGGGGTGAAT ATGACCAAAG ACCAACACTT 
CCCTATGTTG GAGACCCAAT CAGTTCACTC ATTCCTGGTC CTGGGGAGAC GCCCAGCCAG 
TTTCCTCCAC TGAGACCACG CTTTGATCCA GTTGGCCCAC TTCCAGGACC TAACCCCATC 
TTGCCAGGGC GAGGCGGCCC CAATGACAGA TTTCCCTTTA GACCCAGCAG GGGTCGGCCA 
ACTGATGGCC GGCTGTCATT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244919.1
CDS	383..1609
Translation	MQDEQPSDSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM

Target ORF information:

RefSeq Version	NM_001257990.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 7 (FBXO7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257990.1

ORF Insert Sequence:

ATGCAGGATG AACAACCAAG TGATTCATTC CAAGGACAGG CAGCCCAGTC TGGTGTTTGG 
AATGACGACA GTATGTTAGG GCCTAGTCAA AATTTTGAAG CTGAGTCAAT TCAAGATAAT 
GCGCATATGG CAGAGGGCAC AGGTTTCTAT CCCTCAGAAC CCATGCTCTG TAGTGAATCG 
GTGGAAGGGC AAGTGCCACA TTCATTAGAG ACCTTGTATC AATCAGCTGA CTGTTCTGAT 
GCCAATGATG CCTTGATAGT GTTGATACAT CTTCTCATGT TGGAGTCAGG TTACATACCT 
CAGGGCACCG AAGCCAAAGC ACTGTCCATG CCGGAGAAGT GGAAGTTGAG CGGGGTGTAT 
AAGCTGCAGT ACATGCATCC TCTCTGCGAG GGCAGCTCCG CTACTCTCAC CTGTGTGCCT 
TTGGGAAACC TGATTGTTGT AAATGCTACA CTAAAAATCA ACAATGAGAT TAGAAGTGTG 
AAAAGATTGC AGCTGCTACC AGAATCTTTT ATTTGCAAAG AGAAACTAGG GGAAAATGTA 
GCCAACATAT ACAAAGATCT TCAGAAACTC TCTCGCCTCT TTAAAGACCA GCTGGTGTAT 
CCTCTTCTGG CTTTTACCCG ACAAGCACTG AACCTACCAG ATGTATTTGG GTTGGTCGTC 
CTCCCATTGG AACTGAAACT ACGGATCTTC CGACTTCTGG ATGTTCGTTC CGTCTTGTCT 
TTGTCTGCGG TTTGTCGTGA CCTCTTTACT GCTTCAAATG ACCCACTCCT GTGGAGGTTT 
TTATATCTGC GTGATTTTCG AGACAATACT GTCAGAGTTC AAGACACAGA TTGGAAAGAA 
CTGTACAGGA AGAGGCACAT ACAAAGAAAA GAATCCCCGA AAGGGCGGTT TGTGATGCTC 
CTGCCATCGT CAACTCACAC CATTCCATTC TATCCCAACC CCTTGCACCC TAGGCCATTT 
CCTAGCTCCC GCCTTCCTCC AGGAATTATC GGGGGTGAAT ATGACCAAAG ACCAACACTT 
CCCTATGTTG GAGACCCAAT CAGTTCACTC ATTCCTGGTC CTGGGGAGAC GCCCAGCCAG 
TTTCCTCCAC TGAGACCACG CTTTGATCCA GTTGGCCCAC TTCCAGGACC TAACCCCATC 
TTGCCAGGGC GAGGCGGCCC CAATGACAGA TTTCCCTTTA GACCCAGCAG GGGTCGGCCA 
ACTGATGGCC GGCTGTCATT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO7 ( XM_024452207.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307975.1 Homo sapiens F-box protein 7 (FBXO7), transcript variant X1, mRNA.

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CloneID	OHu21498
Clone ID Related Accession (Same CDS sequence)	XM_024452207.1 , NM_001257990.1
Accession Version	XM_024452207.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box only protein 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGATG AACAACCAAG TGATTCATTC CAAGGACAGG CAGCCCAGTC TGGTGTTTGG 
AATGACGACA GTATGTTAGG GCCTAGTCAA AATTTTGAAG CTGAGTCAAT TCAAGATAAT 
GCGCATATGG CAGAGGGCAC AGGTTTCTAT CCCTCAGAAC CCATGCTCTG TAGTGAATCG 
GTGGAAGGGC AAGTGCCACA TTCATTAGAG ACCTTGTATC AATCAGCTGA CTGTTCTGAT 
GCCAATGATG CCTTGATAGT GTTGATACAT CTTCTCATGT TGGAGTCAGG TTACATACCT 
CAGGGCACCG AAGCCAAAGC ACTGTCCATG CCGGAGAAGT GGAAGTTGAG CGGGGTGTAT 
AAGCTGCAGT ACATGCATCC TCTCTGCGAG GGCAGCTCCG CTACTCTCAC CTGTGTGCCT 
TTGGGAAACC TGATTGTTGT AAATGCTACA CTAAAAATCA ACAATGAGAT TAGAAGTGTG 
AAAAGATTGC AGCTGCTACC AGAATCTTTT ATTTGCAAAG AGAAACTAGG GGAAAATGTA 
GCCAACATAT ACAAAGATCT TCAGAAACTC TCTCGCCTCT TTAAAGACCA GCTGGTGTAT 
CCTCTTCTGG CTTTTACCCG ACAAGCACTG AACCTACCAG ATGTATTTGG GTTGGTCGTC 
CTCCCATTGG AACTGAAACT ACGGATCTTC CGACTTCTGG ATGTTCGTTC CGTCTTGTCT 
TTGTCTGCGG TTTGTCGTGA CCTCTTTACT GCTTCAAATG ACCCACTCCT GTGGAGGTTT 
TTATATCTGC GTGATTTTCG AGACAATACT GTCAGAGTTC AAGACACAGA TTGGAAAGAA 
CTGTACAGGA AGAGGCACAT ACAAAGAAAA GAATCCCCGA AAGGGCGGTT TGTGATGCTC 
CTGCCATCGT CAACTCACAC CATTCCATTC TATCCCAACC CCTTGCACCC TAGGCCATTT 
CCTAGCTCCC GCCTTCCTCC AGGAATTATC GGGGGTGAAT ATGACCAAAG ACCAACACTT 
CCCTATGTTG GAGACCCAAT CAGTTCACTC ATTCCTGGTC CTGGGGAGAC GCCCAGCCAG 
TTTCCTCCAC TGAGACCACG CTTTGATCCA GTTGGCCCAC TTCCAGGACC TAACCCCATC 
TTGCCAGGGC GAGGCGGCCC CAATGACAGA TTTCCCTTTA GACCCAGCAG GGGTCGGCCA 
ACTGATGGCC GGCTGTCATT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307975.1
CDS	512..1738
Translation	MQDEQPSDSFQGQAAQSGVWNDDSMLGPSQNFEAESIQDNAHMAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM

Target ORF information:

RefSeq Version	XM_024452207.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 7 (FBXO7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452207.1

ORF Insert Sequence:

ATGCAGGATG AACAACCAAG TGATTCATTC CAAGGACAGG CAGCCCAGTC TGGTGTTTGG 
AATGACGACA GTATGTTAGG GCCTAGTCAA AATTTTGAAG CTGAGTCAAT TCAAGATAAT 
GCGCATATGG CAGAGGGCAC AGGTTTCTAT CCCTCAGAAC CCATGCTCTG TAGTGAATCG 
GTGGAAGGGC AAGTGCCACA TTCATTAGAG ACCTTGTATC AATCAGCTGA CTGTTCTGAT 
GCCAATGATG CCTTGATAGT GTTGATACAT CTTCTCATGT TGGAGTCAGG TTACATACCT 
CAGGGCACCG AAGCCAAAGC ACTGTCCATG CCGGAGAAGT GGAAGTTGAG CGGGGTGTAT 
AAGCTGCAGT ACATGCATCC TCTCTGCGAG GGCAGCTCCG CTACTCTCAC CTGTGTGCCT 
TTGGGAAACC TGATTGTTGT AAATGCTACA CTAAAAATCA ACAATGAGAT TAGAAGTGTG 
AAAAGATTGC AGCTGCTACC AGAATCTTTT ATTTGCAAAG AGAAACTAGG GGAAAATGTA 
GCCAACATAT ACAAAGATCT TCAGAAACTC TCTCGCCTCT TTAAAGACCA GCTGGTGTAT 
CCTCTTCTGG CTTTTACCCG ACAAGCACTG AACCTACCAG ATGTATTTGG GTTGGTCGTC 
CTCCCATTGG AACTGAAACT ACGGATCTTC CGACTTCTGG ATGTTCGTTC CGTCTTGTCT 
TTGTCTGCGG TTTGTCGTGA CCTCTTTACT GCTTCAAATG ACCCACTCCT GTGGAGGTTT 
TTATATCTGC GTGATTTTCG AGACAATACT GTCAGAGTTC AAGACACAGA TTGGAAAGAA 
CTGTACAGGA AGAGGCACAT ACAAAGAAAA GAATCCCCGA AAGGGCGGTT TGTGATGCTC 
CTGCCATCGT CAACTCACAC CATTCCATTC TATCCCAACC CCTTGCACCC TAGGCCATTT 
CCTAGCTCCC GCCTTCCTCC AGGAATTATC GGGGGTGAAT ATGACCAAAG ACCAACACTT 
CCCTATGTTG GAGACCCAAT CAGTTCACTC ATTCCTGGTC CTGGGGAGAC GCCCAGCCAG 
TTTCCTCCAC TGAGACCACG CTTTGATCCA GTTGGCCCAC TTCCAGGACC TAACCCCATC 
TTGCCAGGGC GAGGCGGCCC CAATGACAGA TTTCCCTTTA GACCCAGCAG GGGTCGGCCA 
ACTGATGGCC GGCTGTCATT CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO7 ( XM_011530106.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528408.1 Homo sapiens F-box protein 7 (FBXO7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu66494
Clone ID Related Accession (Same CDS sequence)	XM_011530106.1
Accession Version	XM_011530106.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box only protein 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGG GCACAGGTTT CTATCCCTCA GAACCCATGC TCTGTAGTGA ATCGGTGGAA 
GGGCAAGTGC CACATTCATT AGAGACCTTG TATCAATCAG CTGACTGTTC TGATGCCAAT 
GATGCCTTGA TAGTGTTGAT ACATCTTCTC ATGTTGGAGT CAGGTTACAT ACCTCAGGGC 
ACCGAAGCCA AAGCACTGTC CATGCCGGAG AAGTGGAAGT TGAGCGGGGT GTATAAGCTG 
CAGTACATGC ATCCTCTCTG CGAGGGCAGC TCCGCTACTC TCACCTGTGT GCCTTTGGGA 
AACCTGATTG TTGTAAATGC TACACTAAAA ATCAACAATG AGATTAGAAG TGTGAAAAGA 
TTGCAGCTGC TACCAGAATC TTTTATTTGC AAAGAGAAAC TAGGGGAAAA TGTAGCCAAC 
ATATACAAAG ATCTTCAGAA ACTCTCTCGC CTCTTTAAAG ACCAGCTGGT GTATCCTCTT 
CTGGCTTTTA CCCGACAAGC ACTGAACCTA CCAGATGTAT TTGGGTTGGT CGTCCTCCCA 
TTGGAACTGA AACTACGGAT CTTCCGACTT CTGGATGTTC GTTCCGTCTT GTCTTTGTCT 
GCGGTTTGTC GTGACCTCTT TACTGCTTCA AATGACCCAC TCCTGTGGAG GTTTTTATAT 
CTGCGTGATT TTCGAGACAA TACTGTCAGA GTTCAAGACA CAGATTGGAA AGAACTGTAC 
AGGAAGAGGC ACATACAAAG AAAAGAATCC CCGAAAGGGC GGTTTGTGAT GCTCCTGCCA 
TCGTCAACTC ACACCATTCC ATTCTATCCC AACCCCTTGC ACCCTAGGCC ATTTCCTAGC 
TCCCGCCTTC CTCCAGGAAT TATCGGGGGT GAATATGACC AAAGACCAAC ACTTCCCTAT 
GTTGGAGACC CAATCAGTTC ACTCATTCCT GGTCCTGGGG AGACGCCCAG CCAGTTTCCT 
CCACTGAGAC CACGCTTTGA TCCAGTTGGC CCACTTCCAG GACCTAACCC CATCTTGCCA 
GGGCGAGGCG GCCCCAATGA CAGATTTCCC TTTAGACCCA GCAGGGGTCG GCCAACTGAT 
GGCCGGCTGT CATTCATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528408.1
CDS	495..1595
Translation	MAEGTGFYPSEPMLCSESVEGQVPHSLETLYQSADCSDANDALIVLIHLLMLESGYIPQGTEAKALSMPEKWKLSGVYKLQYMHPLCEGSSATLTCVPLGNLIVVNATLKINNEIRSVKRLQLLPESFICKEKLGENVANIYKDLQKLSRLFKDQLVYPLLAFTRQALNLPDVFGLVVLPLELKLRIFRLLDVRSVLSLSAVCRDLFTASNDPLLWRFLYLRDFRDNTVRVQDTDWKELYRKRHIQRKESPKGRFVMLLPSSTHTIPFYPNPLHPRPFPSSRLPPGIIGGEYDQRPTLPYVGDPISSLIPGPGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDGRLSFM

Target ORF information:

RefSeq Version	XM_011530106.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 7 (FBXO7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530106.1

ORF Insert Sequence:

ATGGCAGAGG GCACAGGTTT CTATCCCTCA GAACCCATGC TCTGTAGTGA ATCGGTGGAA 
GGGCAAGTGC CACATTCATT AGAGACCTTG TATCAATCAG CTGACTGTTC TGATGCCAAT 
GATGCCTTGA TAGTGTTGAT ACATCTTCTC ATGTTGGAGT CAGGTTACAT ACCTCAGGGC 
ACCGAAGCCA AAGCACTGTC CATGCCGGAG AAGTGGAAGT TGAGCGGGGT GTATAAGCTG 
CAGTACATGC ATCCTCTCTG CGAGGGCAGC TCCGCTACTC TCACCTGTGT GCCTTTGGGA 
AACCTGATTG TTGTAAATGC TACACTAAAA ATCAACAATG AGATTAGAAG TGTGAAAAGA 
TTGCAGCTGC TACCAGAATC TTTTATTTGC AAAGAGAAAC TAGGGGAAAA TGTAGCCAAC 
ATATACAAAG ATCTTCAGAA ACTCTCTCGC CTCTTTAAAG ACCAGCTGGT GTATCCTCTT 
CTGGCTTTTA CCCGACAAGC ACTGAACCTA CCAGATGTAT TTGGGTTGGT CGTCCTCCCA 
TTGGAACTGA AACTACGGAT CTTCCGACTT CTGGATGTTC GTTCCGTCTT GTCTTTGTCT 
GCGGTTTGTC GTGACCTCTT TACTGCTTCA AATGACCCAC TCCTGTGGAG GTTTTTATAT 
CTGCGTGATT TTCGAGACAA TACTGTCAGA GTTCAAGACA CAGATTGGAA AGAACTGTAC 
AGGAAGAGGC ACATACAAAG AAAAGAATCC CCGAAAGGGC GGTTTGTGAT GCTCCTGCCA 
TCGTCAACTC ACACCATTCC ATTCTATCCC AACCCCTTGC ACCCTAGGCC ATTTCCTAGC 
TCCCGCCTTC CTCCAGGAAT TATCGGGGGT GAATATGACC AAAGACCAAC ACTTCCCTAT 
GTTGGAGACC CAATCAGTTC ACTCATTCCT GGTCCTGGGG AGACGCCCAG CCAGTTTCCT 
CCACTGAGAC CACGCTTTGA TCCAGTTGGC CCACTTCCAG GACCTAACCC CATCTTGCCA 
GGGCGAGGCG GCCCCAATGA CAGATTTCCC TTTAGACCCA GCAGGGGTCG GCCAACTGAT 
GGCCGGCTGT CATTCATGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mechanistic contributions of FBXO7 to Parkinson disease.
Journal of neurochemistry144(2)118-127(2018 Jan)
Joseph S,Schulz JB,Stegm?ller J

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
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A High-Density Map for Navigating the Human Polycomb Complexome.
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FBXO7 cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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