Gene Symbol | GABRA2 |
Entrez Gene ID | 2555 |
Full Name | gamma-aminobutyric acid type A receptor alpha2 subunit |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]. |
Disorder MIM: | |
Disorder Html: | {Alcohol dependence, susceptibility to}, 103780 (3) |