Gene Symbol | XRCC6 |
Entrez Gene ID | 2547 |
Full Name | X-ray repair cross complementing 6 |
Synonyms | CTC75,CTCBF,G22P1,KU70,ML8,TLAA |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |