The following RNF169 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RNF169 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu05869 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001098638.2 , NM_001098638.1 | |
| Accession Version | NM_001098638.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-10 | |
| Organism | Homo sapiens(human) | |
| Product | E3 ubiquitin-protein ligase RNF169 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000560.4, AB082522.1 and BU735906.1. On Nov 23, 2018 this sequence version replaced NM_001098638.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB082522.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000299563.5/ ENSP00000299563.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001092108.1 |
| CDS | 33..2159 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001098638.2 |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu05869 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001098638.2 , NM_001098638.1 | |
| Accession Version | NM_001098638.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-09-10 | |
| Organism | Homo sapiens(human) | |
| Product | E3 ubiquitin-protein ligase RNF169 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB082522.1, AP000560.4 and BU735906.1. On or before Jun 26, 2007 this sequence version replaced XM_495886.3, XM_940188.2. ##Evidence-Data-START## Transcript exon combination :: AB082522.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001092108.1 |
| CDS | 14..2140 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001098638.1 |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu78266 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011544889.2 , XM_011544889.3 | |
| Accession Version | XM_011544889.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-05 | |
| Organism | Homo sapiens(human) | |
| Product | E3 ubiquitin-protein ligase RNF169 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544889.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011543191.1 |
| CDS | 26..2215 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011544889.2 |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu78266 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011544889.2 , XM_011544889.3 | |
| Accession Version | XM_011544889.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-05 | |
| Organism | Homo sapiens(human) | |
| Product | E3 ubiquitin-protein ligase RNF169 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011544889.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011543191.1 |
| CDS | 26..2215 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011544889.3 |
1 | ATGGCGGCTG CAGGTCCGAG TACTCGGGCC TCTTCCGCGG CGGCAGCAGC CGCTCTGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18. |
Dual-utility NLS drives RNF169-dependent DNA damage responses. |
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage. |
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. |
