FZD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FZD2
Entrez Gene ID	2535
Full Name	frizzled class receptor 2
Synonyms	Fz2,fz-2,fzE2,hFz2
General protein information	Preferred Names frizzled class receptor 2 Names frizzled-2 frizzled 2, seven transmembrane spanning receptor frizzled family receptor 2 frizzled homolog 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.31
Summary	This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010].
Disorder MIM:	600667

mRNA and Protein(s)

mRNA	Protein	Name
NM_001466.3	NP_001457.1	frizzled-2 precursor
NM_001466.4	NP_001457.1	frizzled-2 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FZD2	XP_003315471.1
Canis lupus familiaris (dog)	FZD2	XP_548060.2
Bos taurus (cattle)	FZD2	XP_003587503.1
Gallus gallus (chicken)	FZD2	NP_989553.1
Danio rerio (zebrafish)	fzd2	NP_571215.1
Xenopus tropicalis (tropical clawed frog)	fzd2	NP_001008449.1
Mus musculus (house mouse)	Fzd2	NP_065256.1
	FZD2	XP_001101358.2
Homo sapiens (human)	FZD2	NP_001457.1
Rattus norvegicus (Norway rat)	Fzd2	NP_742032.1

Gene Ontology
Bibliography

Related articles in PubMed

Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway.
Qi B, Wang Y, Chen ZJ, Li XN, Qi Y, Yang Y, Cui GH, Guo HZ, Li WH, Zhao S
World journal of gastroenterology23(45)7965-7977(2017 Dec)

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.
Voloshanenko O, Gmach P, Winter J, Kranz D, Boutros M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)4832-4844(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Treatment of the cell lines with Fzd2 siRNA resulted in significantly reduced migration and invasiveness but did not affect proliferation.Patients with high Fzd2 expression had significantly poorer recurrencefree survival than those with low expression
Title: Clinical implication of Frizzled 2 expression and its association with epithelial-to-mesenchymal transition in hepatocellular carcinoma.

Fzd2 did not influence the proliferation of EC cells.
Title: Promotion of epithelial-mesenchymal transition by Frizzled2 is involved in the metastasis of endometrial cancer.

our study suggests a role for FZD2 in high-risk neuroblastoma cell growth
Title: Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with ?-catenin-dependent and ?-catenin-independent signaling pathways.

Sonazoid enhanced sonoporation of the cells with the diagnostic US device and the suppression of proliferation of both HCC cell lines by shRNA-Fz2.
Title: Suppression of hepatocellular carcinoma cell proliferation by short hairpin RNA of frizzled?2 with Sonazoid-enhanced irradiation.

the present study demonstrated that Fzd2 contributes to the migration and invasion of OSCC cells, at least partly through regulation of the STAT3 pathway
Title: Frizzled2 mediates the migration and invasion of human oral squamous cell carcinoma cells through the regulation of the signal transducer and activator of transcription-3 signaling pathway.

The following FZD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FZD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30770	NM_001466.4 Latest version!	Homo sapiens frizzled class receptor 2 (FZD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu30770	NM_001466.3	Homo sapiens frizzled class receptor 2 (FZD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FZD2 ( NM_001466.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001457.1 Homo sapiens frizzled class receptor 2 (FZD2), mRNA.

Price & Availability↑

CloneID	OHu30770
Clone ID Related Accession (Same CDS sequence)	NM_001466.3 , NM_001466.4
Accession Version	NM_001466.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	frizzled-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN417837.1, BC052266.1, AC103703.5, AW023425.1 and AI376463.1. On Dec 10, 2010 this sequence version replaced NM_001466.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGCGGCCCC GCAGCGCCCT GCCCCGCCTG CTGCTGCCGC TGCTGCTGCT GCCCGCCGCC 
GGGCCGGCCC AGTTCCACGG GGAGAAGGGC ATCTCCATCC CGGACCACGG CTTCTGCCAG 
CCCATCTCCA TCCCGCTGTG CACGGACATC GCCTACAACC AGACCATCAT GCCCAACCTT 
CTGGGCCACA CGAACCAGGA GGACGCAGGC CTAGAGGTGC ACCAGTTCTA TCCGCTGGTG 
AAGGTGCAGT GCTCGCCCGA ACTGCGCTTC TTCCTGTGCT CCATGTACGC ACCCGTGTGC 
ACCGTGCTGG AACAGGCCAT CCCGCCGTGC CGCTCTATCT GTGAGCGCGC GCGCCAGGGC 
TGCGAAGCCC TCATGAACAA GTTCGGTTTT CAGTGGCCCG AGCGCCTGCG CTGCGAGCAC 
TTCCCGCGCC ACGGCGCCGA GCAGATCTGC GTCGGCCAGA ACCACTCCGA GGACGGAGCT 
CCCGCGCTAC TCACCACCGC GCCGCCGCCG GGACTGCAGC CGGGTGCCGG GGGCACCCCG 
GGTGGCCCGG GCGGCGGCGG CGCTCCCCCG CGCTACGCCA CGCTGGAGCA CCCCTTCCAC 
TGCCCGCGCG TCCTCAAGGT GCCATCCTAT CTCAGCTACA AGTTTCTGGG CGAGCGTGAT 
TGTGCTGCGC CCTGCGAACC TGCGCGGCCC GATGGTTCCA TGTTCTTCTC ACAGGAGGAG 
ACGCGTTTCG CGCGCCTCTG GATCCTCACC TGGTCGGTGC TGTGCTGCGC TTCCACCTTC 
TTCACTGTCA CCACGTACTT GGTAGACATG CAGCGCTTCC GCTACCCAGA GCGGCCTATC 
ATTTTTCTGT CGGGCTGCTA CACCATGGTG TCGGTGGCCT ACATCGCGGG CTTCGTGCTC 
CAGGAGCGCG TGGTGTGCAA CGAGCGCTTC TCCGAGGACG GTTACCGCAC GGTGGTGCAG 
GGCACCAAGA AGGAGGGCTG CACCATCCTC TTCATGATGC TCTACTTCTT CAGCATGGCC 
AGCTCCATCT GGTGGGTCAT CCTGTCGCTC ACCTGGTTCC TGGCAGCCGG CATGAAGTGG 
GGCCACGAGG CCATCGAGGC CAACTCTCAG TACTTCCACC TGGCCGCCTG GGCCGTGCCG 
GCCGTCAAGA CCATCACCAT CCTGGCCATG GGCCAGATCG ACGGCGACCT GCTGAGCGGC 
GTGTGCTTCG TAGGCCTCAA CAGCCTGGAC CCGCTGCGGG GCTTCGTGCT AGCGCCGCTC 
TTCGTGTACC TGTTCATCGG CACGTCCTTC CTCCTGGCCG GCTTCGTGTC GCTCTTCCGC 
ATCCGCACCA TCATGAAGCA CGACGGCACC AAGACCGAAA AGCTGGAGCG GCTCATGGTG 
CGCATCGGCG TCTTCTCCGT GCTCTACACA GTGCCCGCCA CCATCGTCAT CGCTTGCTAC 
TTCTACGAGC AGGCCTTCCG CGAGCACTGG GAGCGCTCGT GGGTGAGCCA GCACTGCAAG 
AGCCTGGCCA TCCCGTGCCC GGCGCACTAC ACGCCGCGCA TGTCGCCCGA CTTCACGGTC 
TACATGATCA AATACCTCAT GACGCTCATC GTGGGCATCA CGTCGGGCTT CTGGATCTGG 
TCGGGCAAGA CGCTGCACTC GTGGAGGAAG TTCTACACTC GCCTCACCAA CAGCCGACAC 
GGTGAGACCA CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001457.1
CDS	246..1943
Translation	MRPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNSRHGETTV

Target ORF information:

RefSeq Version	NM_001466.3
Organism	Homo sapiens(human)
Definition	Homo sapiens frizzled class receptor 2 (FZD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001466.3

ORF Insert Sequence:

ATGCGGCCCC GCAGCGCCCT GCCCCGCCTG CTGCTGCCGC TGCTGCTGCT GCCCGCCGCC 
GGGCCGGCCC AGTTCCACGG GGAGAAGGGC ATCTCCATCC CGGACCACGG CTTCTGCCAG 
CCCATCTCCA TCCCGCTGTG CACGGACATC GCCTACAACC AGACCATCAT GCCCAACCTT 
CTGGGCCACA CGAACCAGGA GGACGCAGGC CTAGAGGTGC ACCAGTTCTA TCCGCTGGTG 
AAGGTGCAGT GCTCGCCCGA ACTGCGCTTC TTCCTGTGCT CCATGTACGC ACCCGTGTGC 
ACCGTGCTGG AACAGGCCAT CCCGCCGTGC CGCTCTATCT GTGAGCGCGC GCGCCAGGGC 
TGCGAAGCCC TCATGAACAA GTTCGGTTTT CAGTGGCCCG AGCGCCTGCG CTGCGAGCAC 
TTCCCGCGCC ACGGCGCCGA GCAGATCTGC GTCGGCCAGA ACCACTCCGA GGACGGAGCT 
CCCGCGCTAC TCACCACCGC GCCGCCGCCG GGACTGCAGC CGGGTGCCGG GGGCACCCCG 
GGTGGCCCGG GCGGCGGCGG CGCTCCCCCG CGCTACGCCA CGCTGGAGCA CCCCTTCCAC 
TGCCCGCGCG TCCTCAAGGT GCCATCCTAT CTCAGCTACA AGTTTCTGGG CGAGCGTGAT 
TGTGCTGCGC CCTGCGAACC TGCGCGGCCC GATGGTTCCA TGTTCTTCTC ACAGGAGGAG 
ACGCGTTTCG CGCGCCTCTG GATCCTCACC TGGTCGGTGC TGTGCTGCGC TTCCACCTTC 
TTCACTGTCA CCACGTACTT GGTAGACATG CAGCGCTTCC GCTACCCAGA GCGGCCTATC 
ATTTTTCTGT CGGGCTGCTA CACCATGGTG TCGGTGGCCT ACATCGCGGG CTTCGTGCTC 
CAGGAGCGCG TGGTGTGCAA CGAGCGCTTC TCCGAGGACG GTTACCGCAC GGTGGTGCAG 
GGCACCAAGA AGGAGGGCTG CACCATCCTC TTCATGATGC TCTACTTCTT CAGCATGGCC 
AGCTCCATCT GGTGGGTCAT CCTGTCGCTC ACCTGGTTCC TGGCAGCCGG CATGAAGTGG 
GGCCACGAGG CCATCGAGGC CAACTCTCAG TACTTCCACC TGGCCGCCTG GGCCGTGCCG 
GCCGTCAAGA CCATCACCAT CCTGGCCATG GGCCAGATCG ACGGCGACCT GCTGAGCGGC 
GTGTGCTTCG TAGGCCTCAA CAGCCTGGAC CCGCTGCGGG GCTTCGTGCT AGCGCCGCTC 
TTCGTGTACC TGTTCATCGG CACGTCCTTC CTCCTGGCCG GCTTCGTGTC GCTCTTCCGC 
ATCCGCACCA TCATGAAGCA CGACGGCACC AAGACCGAAA AGCTGGAGCG GCTCATGGTG 
CGCATCGGCG TCTTCTCCGT GCTCTACACA GTGCCCGCCA CCATCGTCAT CGCTTGCTAC 
TTCTACGAGC AGGCCTTCCG CGAGCACTGG GAGCGCTCGT GGGTGAGCCA GCACTGCAAG 
AGCCTGGCCA TCCCGTGCCC GGCGCACTAC ACGCCGCGCA TGTCGCCCGA CTTCACGGTC 
TACATGATCA AATACCTCAT GACGCTCATC GTGGGCATCA CGTCGGGCTT CTGGATCTGG 
TCGGGCAAGA CGCTGCACTC GTGGAGGAAG TTCTACACTC GCCTCACCAA CAGCCGACAC 
GGTGAGACCA CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FZD2 ( NM_001466.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001457.1 Homo sapiens frizzled class receptor 2 (FZD2), mRNA.

Price & Availability↑

CloneID	OHu30770
Clone ID Related Accession (Same CDS sequence)	NM_001466.3 , NM_001466.4
Accession Version	NM_001466.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	frizzled-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC052266.1, AC103703.5, AW023425.1 and AI376463.1. On May 17, 2019 this sequence version replaced NM_001466.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC052266.1, AB017364.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000315323.5/ ENSP00000323901.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGGCCCC GCAGCGCCCT GCCCCGCCTG CTGCTGCCGC TGCTGCTGCT GCCCGCCGCC 
GGGCCGGCCC AGTTCCACGG GGAGAAGGGC ATCTCCATCC CGGACCACGG CTTCTGCCAG 
CCCATCTCCA TCCCGCTGTG CACGGACATC GCCTACAACC AGACCATCAT GCCCAACCTT 
CTGGGCCACA CGAACCAGGA GGACGCAGGC CTAGAGGTGC ACCAGTTCTA TCCGCTGGTG 
AAGGTGCAGT GCTCGCCCGA ACTGCGCTTC TTCCTGTGCT CCATGTACGC ACCCGTGTGC 
ACCGTGCTGG AACAGGCCAT CCCGCCGTGC CGCTCTATCT GTGAGCGCGC GCGCCAGGGC 
TGCGAAGCCC TCATGAACAA GTTCGGTTTT CAGTGGCCCG AGCGCCTGCG CTGCGAGCAC 
TTCCCGCGCC ACGGCGCCGA GCAGATCTGC GTCGGCCAGA ACCACTCCGA GGACGGAGCT 
CCCGCGCTAC TCACCACCGC GCCGCCGCCG GGACTGCAGC CGGGTGCCGG GGGCACCCCG 
GGTGGCCCGG GCGGCGGCGG CGCTCCCCCG CGCTACGCCA CGCTGGAGCA CCCCTTCCAC 
TGCCCGCGCG TCCTCAAGGT GCCATCCTAT CTCAGCTACA AGTTTCTGGG CGAGCGTGAT 
TGTGCTGCGC CCTGCGAACC TGCGCGGCCC GATGGTTCCA TGTTCTTCTC ACAGGAGGAG 
ACGCGTTTCG CGCGCCTCTG GATCCTCACC TGGTCGGTGC TGTGCTGCGC TTCCACCTTC 
TTCACTGTCA CCACGTACTT GGTAGACATG CAGCGCTTCC GCTACCCAGA GCGGCCTATC 
ATTTTTCTGT CGGGCTGCTA CACCATGGTG TCGGTGGCCT ACATCGCGGG CTTCGTGCTC 
CAGGAGCGCG TGGTGTGCAA CGAGCGCTTC TCCGAGGACG GTTACCGCAC GGTGGTGCAG 
GGCACCAAGA AGGAGGGCTG CACCATCCTC TTCATGATGC TCTACTTCTT CAGCATGGCC 
AGCTCCATCT GGTGGGTCAT CCTGTCGCTC ACCTGGTTCC TGGCAGCCGG CATGAAGTGG 
GGCCACGAGG CCATCGAGGC CAACTCTCAG TACTTCCACC TGGCCGCCTG GGCCGTGCCG 
GCCGTCAAGA CCATCACCAT CCTGGCCATG GGCCAGATCG ACGGCGACCT GCTGAGCGGC 
GTGTGCTTCG TAGGCCTCAA CAGCCTGGAC CCGCTGCGGG GCTTCGTGCT AGCGCCGCTC 
TTCGTGTACC TGTTCATCGG CACGTCCTTC CTCCTGGCCG GCTTCGTGTC GCTCTTCCGC 
ATCCGCACCA TCATGAAGCA CGACGGCACC AAGACCGAAA AGCTGGAGCG GCTCATGGTG 
CGCATCGGCG TCTTCTCCGT GCTCTACACA GTGCCCGCCA CCATCGTCAT CGCTTGCTAC 
TTCTACGAGC AGGCCTTCCG CGAGCACTGG GAGCGCTCGT GGGTGAGCCA GCACTGCAAG 
AGCCTGGCCA TCCCGTGCCC GGCGCACTAC ACGCCGCGCA TGTCGCCCGA CTTCACGGTC 
TACATGATCA AATACCTCAT GACGCTCATC GTGGGCATCA CGTCGGGCTT CTGGATCTGG 
TCGGGCAAGA CGCTGCACTC GTGGAGGAAG TTCTACACTC GCCTCACCAA CAGCCGACAC 
GGTGAGACCA CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001457.1
CDS	206..1903
Translation	MRPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNSRHGETTV

Target ORF information:

RefSeq Version	NM_001466.4
Organism	Homo sapiens(human)
Definition	Homo sapiens frizzled class receptor 2 (FZD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001466.4

ORF Insert Sequence:

ATGCGGCCCC GCAGCGCCCT GCCCCGCCTG CTGCTGCCGC TGCTGCTGCT GCCCGCCGCC 
GGGCCGGCCC AGTTCCACGG GGAGAAGGGC ATCTCCATCC CGGACCACGG CTTCTGCCAG 
CCCATCTCCA TCCCGCTGTG CACGGACATC GCCTACAACC AGACCATCAT GCCCAACCTT 
CTGGGCCACA CGAACCAGGA GGACGCAGGC CTAGAGGTGC ACCAGTTCTA TCCGCTGGTG 
AAGGTGCAGT GCTCGCCCGA ACTGCGCTTC TTCCTGTGCT CCATGTACGC ACCCGTGTGC 
ACCGTGCTGG AACAGGCCAT CCCGCCGTGC CGCTCTATCT GTGAGCGCGC GCGCCAGGGC 
TGCGAAGCCC TCATGAACAA GTTCGGTTTT CAGTGGCCCG AGCGCCTGCG CTGCGAGCAC 
TTCCCGCGCC ACGGCGCCGA GCAGATCTGC GTCGGCCAGA ACCACTCCGA GGACGGAGCT 
CCCGCGCTAC TCACCACCGC GCCGCCGCCG GGACTGCAGC CGGGTGCCGG GGGCACCCCG 
GGTGGCCCGG GCGGCGGCGG CGCTCCCCCG CGCTACGCCA CGCTGGAGCA CCCCTTCCAC 
TGCCCGCGCG TCCTCAAGGT GCCATCCTAT CTCAGCTACA AGTTTCTGGG CGAGCGTGAT 
TGTGCTGCGC CCTGCGAACC TGCGCGGCCC GATGGTTCCA TGTTCTTCTC ACAGGAGGAG 
ACGCGTTTCG CGCGCCTCTG GATCCTCACC TGGTCGGTGC TGTGCTGCGC TTCCACCTTC 
TTCACTGTCA CCACGTACTT GGTAGACATG CAGCGCTTCC GCTACCCAGA GCGGCCTATC 
ATTTTTCTGT CGGGCTGCTA CACCATGGTG TCGGTGGCCT ACATCGCGGG CTTCGTGCTC 
CAGGAGCGCG TGGTGTGCAA CGAGCGCTTC TCCGAGGACG GTTACCGCAC GGTGGTGCAG 
GGCACCAAGA AGGAGGGCTG CACCATCCTC TTCATGATGC TCTACTTCTT CAGCATGGCC 
AGCTCCATCT GGTGGGTCAT CCTGTCGCTC ACCTGGTTCC TGGCAGCCGG CATGAAGTGG 
GGCCACGAGG CCATCGAGGC CAACTCTCAG TACTTCCACC TGGCCGCCTG GGCCGTGCCG 
GCCGTCAAGA CCATCACCAT CCTGGCCATG GGCCAGATCG ACGGCGACCT GCTGAGCGGC 
GTGTGCTTCG TAGGCCTCAA CAGCCTGGAC CCGCTGCGGG GCTTCGTGCT AGCGCCGCTC 
TTCGTGTACC TGTTCATCGG CACGTCCTTC CTCCTGGCCG GCTTCGTGTC GCTCTTCCGC 
ATCCGCACCA TCATGAAGCA CGACGGCACC AAGACCGAAA AGCTGGAGCG GCTCATGGTG 
CGCATCGGCG TCTTCTCCGT GCTCTACACA GTGCCCGCCA CCATCGTCAT CGCTTGCTAC 
TTCTACGAGC AGGCCTTCCG CGAGCACTGG GAGCGCTCGT GGGTGAGCCA GCACTGCAAG 
AGCCTGGCCA TCCCGTGCCC GGCGCACTAC ACGCCGCGCA TGTCGCCCGA CTTCACGGTC 
TACATGATCA AATACCTCAT GACGCTCATC GTGGGCATCA CGTCGGGCTT CTGGATCTGG 
TCGGGCAAGA CGCTGCACTC GTGGAGGAAG TTCTACACTC GCCTCACCAA CAGCCGACAC 
GGTGAGACCA CCGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway.
World journal of gastroenterology23(45)7965-7977(2017 Dec)
Qi B,Wang Y,Chen ZJ,Li XN,Qi Y,Yang Y,Cui GH,Guo HZ,Li WH,Zhao S

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)4832-4844(2017 Nov)
Voloshanenko O,Gmach P,Winter J,Kranz D,Boutros M

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FZD2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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