Gene Symbol | ACKR1 |
Entrez Gene ID | 2532 |
Full Name | atypical chemokine receptor 1 (Duffy blood group) |
Synonyms | CCBP1,CD234,DARC,DARC/ACKR1,Dfy,FY,GPD,GpFy,WBCQ1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | [Blood group, Duffy system], 110700 (3); {Malaria, vivax, protection against}, 611162 (3); [White blood cell count QTL], 611862 (3) |