FRG1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FRG1
Entrez Gene ID	2483
Full Name	FSHD region gene 1
Synonyms	FRG1A,FSG1
General protein information	Preferred Names FSHD region gene 1 Names protein FRG1 FSHD region gene 1 protein facioscapulohumeral muscular dystrophy region gene-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q35.2
Summary	This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus. [provided by RefSeq, Jul 2008].
Disorder MIM:	601278

mRNA and Protein(s)

mRNA	Protein	Name
NM_004477.3	NP_004468.1	protein FRG1
NM_004477.2	NP_004468.1	protein FRG1
XM_017007958.1	XP_016863447.1	protein FRG1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FRG1	XP_001136808.1
	FRG1	XP_001090694.1
Canis lupus familiaris (dog)	FRG1	XP_003639616.1
Danio rerio (zebrafish)	zgc:112426	NP_001017793.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002512	XP_312426.2
Homo sapiens (human)	FRG1	NP_004468.1
Gallus gallus (chicken)	FRG1	XP_420681.1
Drosophila melanogaster (fruit fly)	CG6480	NP_649202.1
Xenopus tropicalis (tropical clawed frog)	frg1	NP_001006887.1
Bos taurus (cattle)	FRG1	NP_001069034.1
Mus musculus (house mouse)	Frg1	NP_038550.2
Rattus norvegicus (Norway rat)	Frg1l1	XP_001070964.1
Caenorhabditis elegans (roundworm)	frg-1	NP_499696.2
Rattus norvegicus (Norway rat)	Frg1	XP_001066552.2

Gene Ontology
Bibliography

Related articles in PubMed

Increased FSHD region gene1 expression reduces
Tiwari A, Pattnaik N, Mohanty Jaiswal A, Dixit M
Bioscience reports37(5)(2017 Oct)

Direct interplay between two candidate genes in FSHD muscular dystrophy.
Ferri G, Huichalaf CH, Caccia R, Gabellini D
Human molecular genetics24(5)1256-66(2015 Mar)

FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1).
Feeney SJ, McGrath MJ, Sriratana A, Gehrig SM, Lynch GS, D'Arcy CE, Price JT, McLean CA, Tupler R, Mitchell CA
PloS one10(2)e0117665(2015)

Low penetrance in facioscapulohumeral muscular dystrophy type 1 with large pathological D4Z4 alleles: a cross-sectional multicenter study.
Salort-Campana E, Nguyen K, Bernard R, Jouve E, Sol? G, Nadaj-Pakleza A, Niederhauser J, Charles E, Ollagnon E, Bouhour F, Sacconi S, Echaniz-Laguna A, Desnuelle C, Tranchant C, Vial C, Magdinier F, Bartoli M, Arne-Bes MC, Ferrer X, Kuntzer T, Levy N, Pouget J, Attarian S
Orphanet journal of rare diseases102(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results demonstrate that FRG1 is a direct DUX4 transcriptional target uncovering a novel regulatory circuit contributing to Facioscapulohumeral muscular dystrophy.
Title: Direct interplay between two candidate genes in FSHD muscular dystrophy.

Study showed that the variability in clinical severity of facioscapulohumeral muscular dystrophy in FSHD1 and FSHD2 individuals is dependent on individual differences in susceptibility to D4Z4 hypomethylation.
Title: Inter-individual differences in CpG methylation at D4Z4 correlate with clinical variability in FSHD1 and FSHD2.

FRG1 mice overexpressing FHL1 showed an improvement in the dystrophic phenotype
Title: FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1).

Penetrance of FSHD1 is low for largest alleles in the range of 9-10 RUs, and lower in women than men.
Title: Low penetrance in facioscapulohumeral muscular dystrophy type 1 with large pathological D4Z4 alleles: a cross-sectional multicenter study.

This study suggests a novel role of FRG1 as epigenetic regulator of muscle differentiation and indicates that Suv4-20h1 has a gene-specific function in myogenesis.
Title: FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.

The following FRG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FRG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18822	NM_004477.3 Latest version!	Homo sapiens FSHD region gene 1 (FRG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu95016	XM_017007958.1 Latest version!	Homo sapiens FSHD region gene 1 (FRG1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu18822	NM_004477.2	Homo sapiens FSHD region gene 1 (FRG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FRG1 ( NM_004477.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004468.1 Homo sapiens FSHD region gene 1 (FRG1), mRNA.

Price & Availability↑

CloneID	OHu18822
Clone ID Related Accession (Same CDS sequence)	NM_004477.3 , NM_004477.2
Accession Version	NM_004477.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	protein FRG1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC053997.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_004477.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC053997.1, AK291890.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000226798.9/ ENSP00000226798.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGAGT ACTCCTACGT GAAGTCTACC AAGCTCGTGC TCAAGGGAAC CAAGACGAAG 
AGTAAGAAGA AAAAGAGCAA AGATAAGAAA AGAAAAAGAG AAGAAGATGA AGAAACCCAG 
CTTGATATTG TTGGAATCTG GTGGACAGTA ACAAACTTTG GTGAAATTTC AGGAACCATA 
GCCATTGAAA TGGATAAGGG AACCTATATA CATGCACTCG ACAATGGTCT TTTTACCCTG 
GGAGCTCCAC ACAAAGAAGT TGATGAGGGC CCTAGTCCTC CAGAGCAGTT TACGGCTGTC 
AAATTATCTG ATTCCAGAAT CGCCCTGAAG TCTGGCTATG GAAAATATCT TGGTATAAAT 
TCAGATGGAC TTGTTGTTGG GCGTTCAGAT GCAATTGGAC CAAGAGAACA ATGGGAACCA 
GTCTTTCAAA ATGGGAAAAT GGCTTTGTTG GCCTCAAATA GCTGCTTTAT TAGATGCAAT 
GAAGCAGGGG ACATAGAAGC AAAAAGTAAA ACAGCAGGAG AAGAAGAAAT GATCAAGATT 
AGATCCTGTG CTGAAAGAGA AACCAAGAAA AAAGATGACA TTCCAGAAGA AGACAAAGGA 
AATGTAAAAC AATGTGAAAT CAATTATGTA AAGAAATTTC AGAGCTTCCA AGACCACAAA 
CTTAAAATAA GTAAAGAAGA CAGTAAAATT CTTAAAAAGG CTCGGAAAGA TGGATTTTTG 
CATGAGACGC TTCTGGACAG GAGAGCCAAA TTGAAAGCCG ACAGATACTG CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004468.1
CDS	139..915
Translation	MAEYSYVKSTKLVLKGTKTKSKKKKSKDKKRKREEDEETQLDIVGIWWTVTNFGEISGTIAIEMDKGTYIHALDNGLFTLGAPHKEVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAIGPREQWEPVFQNGKMALLASNSCFIRCNEAGDIEAKSKTAGEEEMIKIRSCAERETKKKDDIPEEDKGNVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK

Target ORF information:

RefSeq Version	NM_004477.3
Organism	Homo sapiens(human)
Definition	Homo sapiens FSHD region gene 1 (FRG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004477.3

ORF Insert Sequence:

ATGGCCGAGT ACTCCTACGT GAAGTCTACC AAGCTCGTGC TCAAGGGAAC CAAGACGAAG 
AGTAAGAAGA AAAAGAGCAA AGATAAGAAA AGAAAAAGAG AAGAAGATGA AGAAACCCAG 
CTTGATATTG TTGGAATCTG GTGGACAGTA ACAAACTTTG GTGAAATTTC AGGAACCATA 
GCCATTGAAA TGGATAAGGG AACCTATATA CATGCACTCG ACAATGGTCT TTTTACCCTG 
GGAGCTCCAC ACAAAGAAGT TGATGAGGGC CCTAGTCCTC CAGAGCAGTT TACGGCTGTC 
AAATTATCTG ATTCCAGAAT CGCCCTGAAG TCTGGCTATG GAAAATATCT TGGTATAAAT 
TCAGATGGAC TTGTTGTTGG GCGTTCAGAT GCAATTGGAC CAAGAGAACA ATGGGAACCA 
GTCTTTCAAA ATGGGAAAAT GGCTTTGTTG GCCTCAAATA GCTGCTTTAT TAGATGCAAT 
GAAGCAGGGG ACATAGAAGC AAAAAGTAAA ACAGCAGGAG AAGAAGAAAT GATCAAGATT 
AGATCCTGTG CTGAAAGAGA AACCAAGAAA AAAGATGACA TTCCAGAAGA AGACAAAGGA 
AATGTAAAAC AATGTGAAAT CAATTATGTA AAGAAATTTC AGAGCTTCCA AGACCACAAA 
CTTAAAATAA GTAAAGAAGA CAGTAAAATT CTTAAAAAGG CTCGGAAAGA TGGATTTTTG 
CATGAGACGC TTCTGGACAG GAGAGCCAAA TTGAAAGCCG ACAGATACTG CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRG1 ( NM_004477.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004468.1 Homo sapiens FSHD region gene 1 (FRG1), mRNA.

Price & Availability↑

CloneID	OHu18822
Clone ID Related Accession (Same CDS sequence)	NM_004477.3 , NM_004477.2
Accession Version	NM_004477.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	protein FRG1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG426031.1, BC053997.1 and AA749391.1. This sequence is a reference standard in the RefSeqGene project. On Aug 23, 2005 this sequence version replaced NM_004477.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L76159.1, SRR1163655.50810.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCCGAGT ACTCCTACGT GAAGTCTACC AAGCTCGTGC TCAAGGGAAC CAAGACGAAG 
AGTAAGAAGA AAAAGAGCAA AGATAAGAAA AGAAAAAGAG AAGAAGATGA AGAAACCCAG 
CTTGATATTG TTGGAATCTG GTGGACAGTA ACAAACTTTG GTGAAATTTC AGGAACCATA 
GCCATTGAAA TGGATAAGGG AACCTATATA CATGCACTCG ACAATGGTCT TTTTACCCTG 
GGAGCTCCAC ACAAAGAAGT TGATGAGGGC CCTAGTCCTC CAGAGCAGTT TACGGCTGTC 
AAATTATCTG ATTCCAGAAT CGCCCTGAAG TCTGGCTATG GAAAATATCT TGGTATAAAT 
TCAGATGGAC TTGTTGTTGG GCGTTCAGAT GCAATTGGAC CAAGAGAACA ATGGGAACCA 
GTCTTTCAAA ATGGGAAAAT GGCTTTGTTG GCCTCAAATA GCTGCTTTAT TAGATGCAAT 
GAAGCAGGGG ACATAGAAGC AAAAAGTAAA ACAGCAGGAG AAGAAGAAAT GATCAAGATT 
AGATCCTGTG CTGAAAGAGA AACCAAGAAA AAAGATGACA TTCCAGAAGA AGACAAAGGA 
AATGTAAAAC AATGTGAAAT CAATTATGTA AAGAAATTTC AGAGCTTCCA AGACCACAAA 
CTTAAAATAA GTAAAGAAGA CAGTAAAATT CTTAAAAAGG CTCGGAAAGA TGGATTTTTG 
CATGAGACGC TTCTGGACAG GAGAGCCAAA TTGAAAGCCG ACAGATACTG CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004468.1
CDS	192..968
Translation	MAEYSYVKSTKLVLKGTKTKSKKKKSKDKKRKREEDEETQLDIVGIWWTVTNFGEISGTIAIEMDKGTYIHALDNGLFTLGAPHKEVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAIGPREQWEPVFQNGKMALLASNSCFIRCNEAGDIEAKSKTAGEEEMIKIRSCAERETKKKDDIPEEDKGNVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK

Target ORF information:

RefSeq Version	NM_004477.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FSHD region gene 1 (FRG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004477.2

ORF Insert Sequence:

ATGGCCGAGT ACTCCTACGT GAAGTCTACC AAGCTCGTGC TCAAGGGAAC CAAGACGAAG 
AGTAAGAAGA AAAAGAGCAA AGATAAGAAA AGAAAAAGAG AAGAAGATGA AGAAACCCAG 
CTTGATATTG TTGGAATCTG GTGGACAGTA ACAAACTTTG GTGAAATTTC AGGAACCATA 
GCCATTGAAA TGGATAAGGG AACCTATATA CATGCACTCG ACAATGGTCT TTTTACCCTG 
GGAGCTCCAC ACAAAGAAGT TGATGAGGGC CCTAGTCCTC CAGAGCAGTT TACGGCTGTC 
AAATTATCTG ATTCCAGAAT CGCCCTGAAG TCTGGCTATG GAAAATATCT TGGTATAAAT 
TCAGATGGAC TTGTTGTTGG GCGTTCAGAT GCAATTGGAC CAAGAGAACA ATGGGAACCA 
GTCTTTCAAA ATGGGAAAAT GGCTTTGTTG GCCTCAAATA GCTGCTTTAT TAGATGCAAT 
GAAGCAGGGG ACATAGAAGC AAAAAGTAAA ACAGCAGGAG AAGAAGAAAT GATCAAGATT 
AGATCCTGTG CTGAAAGAGA AACCAAGAAA AAAGATGACA TTCCAGAAGA AGACAAAGGA 
AATGTAAAAC AATGTGAAAT CAATTATGTA AAGAAATTTC AGAGCTTCCA AGACCACAAA 
CTTAAAATAA GTAAAGAAGA CAGTAAAATT CTTAAAAAGG CTCGGAAAGA TGGATTTTTG 
CATGAGACGC TTCTGGACAG GAGAGCCAAA TTGAAAGCCG ACAGATACTG CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FRG1 ( XM_017007958.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863447.1 Homo sapiens FSHD region gene 1 (FRG1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu95016
Clone ID Related Accession (Same CDS sequence)	XM_017007958.1
Accession Version	XM_017007958.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein FRG1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACTCGA CAATGGTCTT TTTACCCTGG GAGCTCCACA CAAAGAAGGG GAAAATGGCT 
TTGTTGGCCT CAAATAGCTG CTTTATTAGA TGCAATGAAG CAGGGGACAT AGAAGCAAAA 
AGTAAAACAG CAGGAGAAGA AGAAATGATC AAGATTAGAT CCTGTGCTGA AAGAGAAACC 
AAGAAAAAAG ATGACATTCC AGAAGAAGAC AAAGGAAATG TAAAACAATG TGAAATCAAT 
TATGTAAAGA AATTTCAGAG CTTCCAAGAC CACAAACTTA AAATAAGTAA AGAAGACAGT 
AAAATTCTTA AAAAGGCTCG GAAAGATGGA TTTTTGCATG AGACGCTTCT GGACAGGAGA 
GCCAAATTGA AAGCCGACAG ATACTGCAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863447.1
CDS	27..419
Translation	MHSTMVFLPWELHTKKGKMALLASNSCFIRCNEAGDIEAKSKTAGEEEMIKIRSCAERETKKKDDIPEEDKGNVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK

Target ORF information:

RefSeq Version	XM_017007958.1
Organism	Homo sapiens(human)
Definition	Homo sapiens FSHD region gene 1 (FRG1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007958.1

ORF Insert Sequence:

ATGCACTCGA CAATGGTCTT TTTACCCTGG GAGCTCCACA CAAAGAAGGG GAAAATGGCT 
TTGTTGGCCT CAAATAGCTG CTTTATTAGA TGCAATGAAG CAGGGGACAT AGAAGCAAAA 
AGTAAAACAG CAGGAGAAGA AGAAATGATC AAGATTAGAT CCTGTGCTGA AAGAGAAACC 
AAGAAAAAAG ATGACATTCC AGAAGAAGAC AAAGGAAATG TAAAACAATG TGAAATCAAT 
TATGTAAAGA AATTTCAGAG CTTCCAAGAC CACAAACTTA AAATAAGTAA AGAAGACAGT 
AAAATTCTTA AAAAGGCTCG GAAAGATGGA TTTTTGCATG AGACGCTTCT GGACAGGAGA 
GCCAAATTGA AAGCCGACAG ATACTGCAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased FSHD region gene1 expression reduces
Bioscience reports37(5)(2017 Oct)
Tiwari A,Pattnaik N,Mohanty Jaiswal A,Dixit M

Direct interplay between two candidate genes in FSHD muscular dystrophy.
Human molecular genetics24(5)1256-66(2015 Mar)
Ferri G,Huichalaf CH,Caccia R,Gabellini D

FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1).
PloS one10(2)e0117665(2015)
Feeney SJ,McGrath MJ,Sriratana A,Gehrig SM,Lynch GS,D'Arcy CE,Price JT,McLean CA,Tupler R,Mitchell CA

Low penetrance in facioscapulohumeral muscular dystrophy type 1 with large pathological D4Z4 alleles: a cross-sectional multicenter study.
Orphanet journal of rare diseases102(2015 Jan)
Salort-Campana E,Nguyen K,Bernard R,Jouve E,Sol? G,Nadaj-Pakleza A,Niederhauser J,Charles E,Ollagnon E,Bouhour F,Sacconi S,Echaniz-Laguna A,Desnuelle C,Tranchant C,Vial C,Magdinier F,Bartoli M,Arne-Bes MC,Ferrer X,Kuntzer T,Levy N,Pouget J,Attarian S

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FRG1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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