Gene Symbol | MTOR |
Entrez Gene ID | 2475 |
Full Name | mechanistic target of rapamycin kinase |
Synonyms | FRAP,FRAP1,FRAP2,RAFT1,RAPT1,SKS |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]. |
Disorder MIM: | |
Disorder Html: | Smith-Kingsmore syndrome, 616638 (3); Focal cortical dysplasia, type II, somatic, 607341 (3) |