ALK cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALK
Entrez Gene ID	238
Full Name	ALK receptor tyrosine kinase
Synonyms	CD246,NBLST3
General protein information	Preferred Names ALK receptor tyrosine kinase Names ALK tyrosine kinase receptor CD246 antigen anaplastic lymphoma receptor tyrosine kinase mutant anaplastic lymphoma kinase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p23.2-p23.1
Summary	This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011].
Disorder MIM:	105590
Disorder Html:	{Neuroblastoma, susceptibility to, 3}, 613014 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_024452779.1	XP_024308547.1	ALK tyrosine kinase receptor isoform X2
NM_004304.4	NP_004295.2	ALK tyrosine kinase receptor isoform 1 precursor
XM_024452778.1	XP_024308546.1	ALK tyrosine kinase receptor isoform X1
NM_004304.5	NP_004295.2	ALK tyrosine kinase receptor isoform 1 precursor
NM_001353765.1	NP_001340694.1	ALK tyrosine kinase receptor isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ALK	XP_003309006.2
Rattus norvegicus (Norway rat)	Alk	NP_001162572.1
Homo sapiens (human)	ALK	NP_004295.2
Danio rerio (zebrafish)	alk	XP_691964.5
Gallus gallus (chicken)	ALK	XP_004940244.1
Canis lupus familiaris (dog)	ALK	XP_540136.3
Mus musculus (house mouse)	Alk	NP_031465.2
Bos taurus (cattle)	LOC536642	XP_002691538.2
Xenopus tropicalis (tropical clawed frog)	LOC100495071	XP_002938468.2

Gene Ontology
Bibliography

Related articles in PubMed

Environmental tobacco smoke exposure and EGFR and ALK alterations in never smokers' lung cancer. Results from the LCRINS study.
Torres-Dur?n M, Ruano-Ravina A, Kelsey KT, Parente-Lamelas I, Leiro-Fern?ndez V, Abdulkader I, Provencio M, Abal-Arca J, Castro-A??n O, Montero-Mart?nez C, Vidal-Garc?a I, Amenedo M, Golpe-G?mez A, Mart?nez C, Guzm?n-Taveras R, Mejuto-Mart? MJ, Fern?ndez-Villar A, Barros-Dios JM
Cancer letters411130-135(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The prevalence of STRN-ALK kinase fusions were determined in papillary thyroid cancer of an adult population

Results show no apparent association between environmental tobacco smoke exposure and ALK translocation.
Title: Environmental tobacco smoke exposure and EGFR and ALK alterations in never smokers' lung cancer. Results from the LCRINS study.

This computational investigation in-sighted the molecular factors involved in crizotinib resistance which enhanced in the identification of new ALK drugs that brings individualized medicine to treat ALK positive NSCLC patients with specific mutations.
Title: Molecular Dynamics Validation of Crizotinib Resistance to ALK Mutations (L1196M and G1269A) and Identification of Specific Inhibitors.

High expression of SLC34A2 was identified in about 2/3 patients and correlated with significantly better patient's overall survival. Epidermal growth factor receptor mutations were detected in about 53% of patients with no statistically significant difference to patient's overall survival. Anaplastic lymphoma kinase rearrangement was found in 8 out of 175 patients, harboring this abnormality leads to shorter overall survi
Title: High expression of SLC34A2 is a favorable prognostic marker in lung adenocarcinoma patients.

ALK+, LBCL cases display a dismal clinical outcome and can only be cured with conventional chemotherapy protocols at the stage of localized disease
Title: Anaplastic lymphoma kinase-positive large B-cell lymphoma: Clinico-pathological study of 17 cases with review of literature.

The following ALK gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALK cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27041	NM_004304.5 Latest version!	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$659.50-$923.30 $1319.00
OHu102985	NM_001353765.1 Latest version!	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
OHu102985	XM_024452779.1 Latest version!	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
OHu104838	XM_024452778.1 Latest version!	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu27041	NM_004304.4	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$659.50-$923.30 $1319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALK ( NM_004304.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004295.2 Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27041
Clone ID Related Accession (Same CDS sequence)	NM_004304.4 , NM_004304.5
Accession Version	NM_004304.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	ALK tyrosine kinase receptor isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA455128.1, EU788004.1 and U62540.1. On Jan 21, 2011 this sequence version replaced NM_004304.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU788003.1, AB209477.4 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGCCA TCGGGCTCCT GTGGCTCCTG CCGCTGCTGC TTTCCACGGC AGCTGTGGGC 
TCCGGGATGG GGACCGGCCA GCGCGCGGGC TCCCCAGCTG CGGGGCCGCC GCTGCAGCCC 
CGGGAGCCAC TCAGCTACTC GCGCCTGCAG AGGAAGAGTC TGGCAGTTGA CTTCGTGGTG 
CCCTCGCTCT TCCGTGTCTA CGCCCGGGAC CTACTGCTGC CACCATCCTC CTCGGAGCTG 
AAGGCTGGCA GGCCCGAGGC CCGCGGCTCG CTAGCTCTGG ACTGCGCCCC GCTGCTCAGG 
TTGCTGGGGC CGGCGCCGGG GGTCTCCTGG ACCGCCGGTT CACCAGCCCC GGCAGAGGCC 
CGGACGCTGT CCAGGGTGCT GAAGGGCGGC TCCGTGCGCA AGCTCCGGCG TGCCAAGCAG 
TTGGTGCTGG AGCTGGGCGA GGAGGCGATC TTGGAGGGTT GCGTCGGGCC CCCCGGGGAG 
GCGGCTGTGG GGCTGCTCCA GTTCAATCTC AGCGAGCTGT TCAGTTGGTG GATTCGCCAA 
GGCGAAGGGC GACTGAGGAT CCGCCTGATG CCCGAGAAGA AGGCGTCGGA AGTGGGCAGA 
GAGGGAAGGC TGTCCGCGGC AATTCGCGCC TCCCAGCCCC GCCTTCTCTT CCAGATCTTC 
GGGACTGGTC ATAGCTCCTT GGAATCACCA ACAAACATGC CTTCTCCTTC TCCTGATTAT 
TTTACATGGA ATCTCACCTG GATAATGAAA GACTCCTTCC CTTTCCTGTC TCATCGCAGC 
CGATATGGTC TGGAGTGCAG CTTTGACTTC CCCTGTGAGC TGGAGTATTC CCCTCCACTG 
CATGACCTCA GGAACCAGAG CTGGTCCTGG CGCCGCATCC CCTCCGAGGA GGCCTCCCAG 
ATGGACTTGC TGGATGGGCC TGGGGCAGAG CGTTCTAAGG AGATGCCCAG AGGCTCCTTT 
CTCCTTCTCA ACACCTCAGC TGACTCCAAG CACACCATCC TGAGTCCGTG GATGAGGAGC 
AGCAGTGAGC ACTGCACACT GGCCGTCTCG GTGCACAGGC ACCTGCAGCC CTCTGGAAGG 
TACATTGCCC AGCTGCTGCC CCACAACGAG GCTGCAAGAG AGATCCTCCT GATGCCCACT 
CCAGGGAAGC ATGGTTGGAC AGTGCTCCAG GGAAGAATCG GGCGTCCAGA CAACCCATTT 
CGAGTGGCCC TGGAATACAT CTCCAGTGGA AACCGCAGCT TGTCTGCAGT GGACTTCTTT 
GCCCTGAAGA ACTGCAGTGA AGGAACATCC CCAGGCTCCA AGATGGCCCT GCAGAGCTCC 
TTCACTTGTT GGAATGGGAC AGTCCTCCAG CTTGGGCAGG CCTGTGACTT CCACCAGGAC 
TGTGCCCAGG GAGAAGATGA GAGCCAGATG TGCCGGAAAC TGCCTGTGGG TTTTTACTGC 
AACTTTGAAG ATGGCTTCTG TGGCTGGACC CAAGGCACAC TGTCACCCCA CACTCCTCAA 
TGGCAGGTCA GGACCCTAAA GGATGCCCGG TTCCAGGACC ACCAAGACCA TGCTCTATTG 
CTCAGTACCA CTGATGTCCC CGCTTCTGAA AGTGCTACAG TGACCAGTGC TACGTTTCCT 
GCACCGATCA AGAGCTCTCC ATGTGAGCTC CGAATGTCCT GGCTCATTCG TGGAGTCTTG 
AGGGGAAACG TGTCCTTGGT GCTAGTGGAG AACAAAACCG GGAAGGAGCA AGGCAGGATG 
GTCTGGCATG TCGCCGCCTA TGAAGGCTTG AGCCTGTGGC AGTGGATGGT GTTGCCTCTC 
CTCGATGTGT CTGACAGGTT CTGGCTGCAG ATGGTCGCAT GGTGGGGACA AGGATCCAGA 
GCCATCGTGG CTTTTGACAA TATCTCCATC AGCCTGGACT GCTACCTCAC CATTAGCGGA 
GAGGACAAGA TCCTGCAGAA TACAGCACCC AAATCAAGAA ACCTGTTTGA GAGAAACCCA 
AACAAGGAGC TGAAACCCGG GGAAAATTCA CCAAGACAGA CCCCCATCTT TGACCCTACA 
GTTCATTGGC TGTTCACCAC ATGTGGGGCC AGCGGGCCCC ATGGCCCCAC CCAGGCACAG 
TGCAACAACG CCTACCAGAA CTCCAACCTG AGCGTGGAGG TGGGGAGCGA GGGCCCCCTG 
AAAGGCATCC AGATCTGGAA GGTGCCAGCC ACCGACACCT ACAGCATCTC GGGCTACGGA 
GCTGCTGGCG GGAAAGGCGG GAAGAACACC ATGATGCGGT CCCACGGCGT GTCTGTGCTG 
GGCATCTTCA ACCTGGAGAA GGATGACATG CTGTACATCC TGGTTGGGCA GCAGGGAGAG 
GACGCCTGCC CCAGTACAAA CCAGTTAATC CAGAAAGTCT GCATTGGAGA GAACAATGTG 
ATAGAAGAAG AAATCCGTGT GAACAGAAGC GTGCATGAGT GGGCAGGAGG CGGAGGAGGA 
GGGGGTGGAG CCACCTACGT ATTTAAGATG AAGGATGGAG TGCCGGTGCC CCTGATCATT 
GCAGCCGGAG GTGGTGGCAG GGCCTACGGG GCCAAGACAG ACACGTTCCA CCCAGAGAGA 
CTGGAGAATA ACTCCTCGGT TCTAGGGCTA AACGGCAATT CCGGAGCCGC AGGTGGTGGA 
GGTGGCTGGA ATGATAACAC TTCCTTGCTC TGGGCCGGAA AATCTTTGCA GGAGGGTGCC 
ACCGGAGGAC ATTCCTGCCC CCAGGCCATG AAGAAGTGGG GGTGGGAGAC AAGAGGGGGT 
TTCGGAGGGG GTGGAGGGGG GTGCTCCTCA GGTGGAGGAG GCGGAGGATA TATAGGCGGC 
AATGCAGCCT CAAACAATGA CCCCGAAATG GATGGGGAAG ATGGGGTTTC CTTCATCAGT 
CCACTGGGCA TCCTGTACAC CCCAGCTTTA AAAGTGATGG AAGGCCACGG GGAAGTGAAT 
ATTAAGCATT ATCTAAACTG CAGTCACTGT GAGGTAGACG AATGTCACAT GGACCCTGAA 
AGCCACAAGG TCATCTGCTT CTGTGACCAC GGGACGGTGC TGGCTGAGGA TGGCGTCTCC 
TGCATTGTGT CACCCACCCC GGAGCCACAC CTGCCACTCT CGCTGATCCT CTCTGTGGTG 
ACCTCTGCCC TCGTGGCCGC CCTGGTCCTG GCTTTCTCCG GCATCATGAT TGTGTACCGC 
CGGAAGCACC AGGAGCTGCA AGCCATGCAG ATGGAGCTGC AGAGCCCTGA GTACAAGCTG 
AGCAAGCTCC GCACCTCGAC CATCATGACC GACTACAACC CCAACTACTG CTTTGCTGGC 
AAGACCTCCT CCATCAGTGA CCTGAAGGAG GTGCCGCGGA AAAACATCAC CCTCATTCGG 
GGTCTGGGCC ATGGCGCCTT TGGGGAGGTG TATGAAGGCC AGGTGTCCGG AATGCCCAAC 
GACCCAAGCC CCCTGCAAGT GGCTGTGAAG ACGCTGCCTG AAGTGTGCTC TGAACAGGAC 
GAACTGGATT TCCTCATGGA AGCCCTGATC ATCAGCAAAT TCAACCACCA GAACATTGTT 
CGCTGCATTG GGGTGAGCCT GCAATCCCTG CCCCGGTTCA TCCTGCTGGA GCTCATGGCG 
GGGGGAGACC TCAAGTCCTT CCTCCGAGAG ACCCGCCCTC GCCCGAGCCA GCCCTCCTCC 
CTGGCCATGC TGGACCTTCT GCACGTGGCT CGGGACATTG CCTGTGGCTG TCAGTATTTG 
GAGGAAAACC ACTTCATCCA CCGAGACATT GCTGCCAGAA ACTGCCTCTT GACCTGTCCA 
GGCCCTGGAA GAGTGGCCAA GATTGGAGAC TTCGGGATGG CCCGAGACAT CTACAGGGCG 
AGCTACTATA GAAAGGGAGG CTGTGCCATG CTGCCAGTTA AGTGGATGCC CCCAGAGGCC 
TTCATGGAAG GAATATTCAC TTCTAAAACA GACACATGGT CCTTTGGAGT GCTGCTATGG 
GAAATCTTTT CTCTTGGATA TATGCCATAC CCCAGCAAAA GCAACCAGGA AGTTCTGGAG 
TTTGTCACCA GTGGAGGCCG GATGGACCCA CCCAAGAACT GCCCTGGGCC TGTATACCGG 
ATAATGACTC AGTGCTGGCA ACATCAGCCT GAAGACAGGC CCAACTTTGC CATCATTTTG 
GAGAGGATTG AATACTGCAC CCAGGACCCG GATGTAATCA ACACCGCTTT GCCGATAGAA 
TATGGTCCAC TTGTGGAAGA GGAAGAGAAA GTGCCTGTGA GGCCCAAGGA CCCTGAGGGG 
GTTCCTCCTC TCCTGGTCTC TCAACAGGCA AAACGGGAGG AGGAGCGCAG CCCAGCTGCC 
CCACCACCTC TGCCTACCAC CTCCTCTGGC AAGGCTGCAA AGAAACCCAC AGCTGCAGAG 
ATCTCTGTTC GAGTCCCTAG AGGGCCGGCC GTGGAAGGGG GACACGTGAA TATGGCATTC 
TCTCAGTCCA ACCCTCCTTC GGAGTTGCAC AAGGTCCACG GATCCAGAAA CAAGCCCACC 
AGCTTGTGGA ACCCAACGTA CGGCTCCTGG TTTACAGAGA AACCCACCAA AAAGAATAAT 
CCTATAGCAA AGAAGGAGCC ACACGACAGG GGTAACCTGG GGCTGGAGGG AAGCTGTACT 
GTCCCACCTA ACGTTGCAAC TGGGAGACTT CCGGGGGCCT CACTGCTCCT AGAGCCCTCT 
TCGCTGACTG CCAATATGAA GGAGGTACCT CTGTTCAGGC TACGTCACTT CCCTTGTGGG 
AATGTCAATT ACGGCTACCA GCAACAGGGC TTGCCCTTAG AAGCCGCTAC TGCCCCTGGA 
GCTGGTCATT ACGAGGATAC CATTCTGAAA AGCAAGAATA GCATGAACCA GCCTGGGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004295.2
CDS	953..5815
Translation	MGAIGLLWLLPLLLSTAAVGSGMGTGQRAGSPAAGPPLQPREPLSYSRLQRKSLAVDFVVPSLFRVYARDLLLPPSSSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPAPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPGEAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQIFGTGHSSLESPTNMPSPSPDYFTWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRIPSEEASQMDLLDGPGAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGWTQGTLSPHTPQWQVRTLKDARFQDHQDHALLLSTTDVPASESATVTSATFPAPIKSSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKILQNTAPKSRNLFERNPNKELKPGENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP

Target ORF information:

RefSeq Version	NM_004304.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004304.4

ORF Insert Sequence:

ATGGGAGCCA TCGGGCTCCT GTGGCTCCTG CCGCTGCTGC TTTCCACGGC AGCTGTGGGC 
TCCGGGATGG GGACCGGCCA GCGCGCGGGC TCCCCAGCTG CGGGGCCGCC GCTGCAGCCC 
CGGGAGCCAC TCAGCTACTC GCGCCTGCAG AGGAAGAGTC TGGCAGTTGA CTTCGTGGTG 
CCCTCGCTCT TCCGTGTCTA CGCCCGGGAC CTACTGCTGC CACCATCCTC CTCGGAGCTG 
AAGGCTGGCA GGCCCGAGGC CCGCGGCTCG CTAGCTCTGG ACTGCGCCCC GCTGCTCAGG 
TTGCTGGGGC CGGCGCCGGG GGTCTCCTGG ACCGCCGGTT CACCAGCCCC GGCAGAGGCC 
CGGACGCTGT CCAGGGTGCT GAAGGGCGGC TCCGTGCGCA AGCTCCGGCG TGCCAAGCAG 
TTGGTGCTGG AGCTGGGCGA GGAGGCGATC TTGGAGGGTT GCGTCGGGCC CCCCGGGGAG 
GCGGCTGTGG GGCTGCTCCA GTTCAATCTC AGCGAGCTGT TCAGTTGGTG GATTCGCCAA 
GGCGAAGGGC GACTGAGGAT CCGCCTGATG CCCGAGAAGA AGGCGTCGGA AGTGGGCAGA 
GAGGGAAGGC TGTCCGCGGC AATTCGCGCC TCCCAGCCCC GCCTTCTCTT CCAGATCTTC 
GGGACTGGTC ATAGCTCCTT GGAATCACCA ACAAACATGC CTTCTCCTTC TCCTGATTAT 
TTTACATGGA ATCTCACCTG GATAATGAAA GACTCCTTCC CTTTCCTGTC TCATCGCAGC 
CGATATGGTC TGGAGTGCAG CTTTGACTTC CCCTGTGAGC TGGAGTATTC CCCTCCACTG 
CATGACCTCA GGAACCAGAG CTGGTCCTGG CGCCGCATCC CCTCCGAGGA GGCCTCCCAG 
ATGGACTTGC TGGATGGGCC TGGGGCAGAG CGTTCTAAGG AGATGCCCAG AGGCTCCTTT 
CTCCTTCTCA ACACCTCAGC TGACTCCAAG CACACCATCC TGAGTCCGTG GATGAGGAGC 
AGCAGTGAGC ACTGCACACT GGCCGTCTCG GTGCACAGGC ACCTGCAGCC CTCTGGAAGG 
TACATTGCCC AGCTGCTGCC CCACAACGAG GCTGCAAGAG AGATCCTCCT GATGCCCACT 
CCAGGGAAGC ATGGTTGGAC AGTGCTCCAG GGAAGAATCG GGCGTCCAGA CAACCCATTT 
CGAGTGGCCC TGGAATACAT CTCCAGTGGA AACCGCAGCT TGTCTGCAGT GGACTTCTTT 
GCCCTGAAGA ACTGCAGTGA AGGAACATCC CCAGGCTCCA AGATGGCCCT GCAGAGCTCC 
TTCACTTGTT GGAATGGGAC AGTCCTCCAG CTTGGGCAGG CCTGTGACTT CCACCAGGAC 
TGTGCCCAGG GAGAAGATGA GAGCCAGATG TGCCGGAAAC TGCCTGTGGG TTTTTACTGC 
AACTTTGAAG ATGGCTTCTG TGGCTGGACC CAAGGCACAC TGTCACCCCA CACTCCTCAA 
TGGCAGGTCA GGACCCTAAA GGATGCCCGG TTCCAGGACC ACCAAGACCA TGCTCTATTG 
CTCAGTACCA CTGATGTCCC CGCTTCTGAA AGTGCTACAG TGACCAGTGC TACGTTTCCT 
GCACCGATCA AGAGCTCTCC ATGTGAGCTC CGAATGTCCT GGCTCATTCG TGGAGTCTTG 
AGGGGAAACG TGTCCTTGGT GCTAGTGGAG AACAAAACCG GGAAGGAGCA AGGCAGGATG 
GTCTGGCATG TCGCCGCCTA TGAAGGCTTG AGCCTGTGGC AGTGGATGGT GTTGCCTCTC 
CTCGATGTGT CTGACAGGTT CTGGCTGCAG ATGGTCGCAT GGTGGGGACA AGGATCCAGA 
GCCATCGTGG CTTTTGACAA TATCTCCATC AGCCTGGACT GCTACCTCAC CATTAGCGGA 
GAGGACAAGA TCCTGCAGAA TACAGCACCC AAATCAAGAA ACCTGTTTGA GAGAAACCCA 
AACAAGGAGC TGAAACCCGG GGAAAATTCA CCAAGACAGA CCCCCATCTT TGACCCTACA 
GTTCATTGGC TGTTCACCAC ATGTGGGGCC AGCGGGCCCC ATGGCCCCAC CCAGGCACAG 
TGCAACAACG CCTACCAGAA CTCCAACCTG AGCGTGGAGG TGGGGAGCGA GGGCCCCCTG 
AAAGGCATCC AGATCTGGAA GGTGCCAGCC ACCGACACCT ACAGCATCTC GGGCTACGGA 
GCTGCTGGCG GGAAAGGCGG GAAGAACACC ATGATGCGGT CCCACGGCGT GTCTGTGCTG 
GGCATCTTCA ACCTGGAGAA GGATGACATG CTGTACATCC TGGTTGGGCA GCAGGGAGAG 
GACGCCTGCC CCAGTACAAA CCAGTTAATC CAGAAAGTCT GCATTGGAGA GAACAATGTG 
ATAGAAGAAG AAATCCGTGT GAACAGAAGC GTGCATGAGT GGGCAGGAGG CGGAGGAGGA 
GGGGGTGGAG CCACCTACGT ATTTAAGATG AAGGATGGAG TGCCGGTGCC CCTGATCATT 
GCAGCCGGAG GTGGTGGCAG GGCCTACGGG GCCAAGACAG ACACGTTCCA CCCAGAGAGA 
CTGGAGAATA ACTCCTCGGT TCTAGGGCTA AACGGCAATT CCGGAGCCGC AGGTGGTGGA 
GGTGGCTGGA ATGATAACAC TTCCTTGCTC TGGGCCGGAA AATCTTTGCA GGAGGGTGCC 
ACCGGAGGAC ATTCCTGCCC CCAGGCCATG AAGAAGTGGG GGTGGGAGAC AAGAGGGGGT 
TTCGGAGGGG GTGGAGGGGG GTGCTCCTCA GGTGGAGGAG GCGGAGGATA TATAGGCGGC 
AATGCAGCCT CAAACAATGA CCCCGAAATG GATGGGGAAG ATGGGGTTTC CTTCATCAGT 
CCACTGGGCA TCCTGTACAC CCCAGCTTTA AAAGTGATGG AAGGCCACGG GGAAGTGAAT 
ATTAAGCATT ATCTAAACTG CAGTCACTGT GAGGTAGACG AATGTCACAT GGACCCTGAA 
AGCCACAAGG TCATCTGCTT CTGTGACCAC GGGACGGTGC TGGCTGAGGA TGGCGTCTCC 
TGCATTGTGT CACCCACCCC GGAGCCACAC CTGCCACTCT CGCTGATCCT CTCTGTGGTG 
ACCTCTGCCC TCGTGGCCGC CCTGGTCCTG GCTTTCTCCG GCATCATGAT TGTGTACCGC 
CGGAAGCACC AGGAGCTGCA AGCCATGCAG ATGGAGCTGC AGAGCCCTGA GTACAAGCTG 
AGCAAGCTCC GCACCTCGAC CATCATGACC GACTACAACC CCAACTACTG CTTTGCTGGC 
AAGACCTCCT CCATCAGTGA CCTGAAGGAG GTGCCGCGGA AAAACATCAC CCTCATTCGG 
GGTCTGGGCC ATGGCGCCTT TGGGGAGGTG TATGAAGGCC AGGTGTCCGG AATGCCCAAC 
GACCCAAGCC CCCTGCAAGT GGCTGTGAAG ACGCTGCCTG AAGTGTGCTC TGAACAGGAC 
GAACTGGATT TCCTCATGGA AGCCCTGATC ATCAGCAAAT TCAACCACCA GAACATTGTT 
CGCTGCATTG GGGTGAGCCT GCAATCCCTG CCCCGGTTCA TCCTGCTGGA GCTCATGGCG 
GGGGGAGACC TCAAGTCCTT CCTCCGAGAG ACCCGCCCTC GCCCGAGCCA GCCCTCCTCC 
CTGGCCATGC TGGACCTTCT GCACGTGGCT CGGGACATTG CCTGTGGCTG TCAGTATTTG 
GAGGAAAACC ACTTCATCCA CCGAGACATT GCTGCCAGAA ACTGCCTCTT GACCTGTCCA 
GGCCCTGGAA GAGTGGCCAA GATTGGAGAC TTCGGGATGG CCCGAGACAT CTACAGGGCG 
AGCTACTATA GAAAGGGAGG CTGTGCCATG CTGCCAGTTA AGTGGATGCC CCCAGAGGCC 
TTCATGGAAG GAATATTCAC TTCTAAAACA GACACATGGT CCTTTGGAGT GCTGCTATGG 
GAAATCTTTT CTCTTGGATA TATGCCATAC CCCAGCAAAA GCAACCAGGA AGTTCTGGAG 
TTTGTCACCA GTGGAGGCCG GATGGACCCA CCCAAGAACT GCCCTGGGCC TGTATACCGG 
ATAATGACTC AGTGCTGGCA ACATCAGCCT GAAGACAGGC CCAACTTTGC CATCATTTTG 
GAGAGGATTG AATACTGCAC CCAGGACCCG GATGTAATCA ACACCGCTTT GCCGATAGAA 
TATGGTCCAC TTGTGGAAGA GGAAGAGAAA GTGCCTGTGA GGCCCAAGGA CCCTGAGGGG 
GTTCCTCCTC TCCTGGTCTC TCAACAGGCA AAACGGGAGG AGGAGCGCAG CCCAGCTGCC 
CCACCACCTC TGCCTACCAC CTCCTCTGGC AAGGCTGCAA AGAAACCCAC AGCTGCAGAG 
ATCTCTGTTC GAGTCCCTAG AGGGCCGGCC GTGGAAGGGG GACACGTGAA TATGGCATTC 
TCTCAGTCCA ACCCTCCTTC GGAGTTGCAC AAGGTCCACG GATCCAGAAA CAAGCCCACC 
AGCTTGTGGA ACCCAACGTA CGGCTCCTGG TTTACAGAGA AACCCACCAA AAAGAATAAT 
CCTATAGCAA AGAAGGAGCC ACACGACAGG GGTAACCTGG GGCTGGAGGG AAGCTGTACT 
GTCCCACCTA ACGTTGCAAC TGGGAGACTT CCGGGGGCCT CACTGCTCCT AGAGCCCTCT 
TCGCTGACTG CCAATATGAA GGAGGTACCT CTGTTCAGGC TACGTCACTT CCCTTGTGGG 
AATGTCAATT ACGGCTACCA GCAACAGGGC TTGCCCTTAG AAGCCGCTAC TGCCCCTGGA 
GCTGGTCATT ACGAGGATAC CATTCTGAAA AGCAAGAATA GCATGAACCA GCCTGGGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALK ( NM_004304.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_004295.2 Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 1, mRNA.

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CloneID	OHu27041
Clone ID Related Accession (Same CDS sequence)	NM_004304.4 , NM_004304.5
Accession Version	NM_004304.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	ALK tyrosine kinase receptor isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA455128.1, EU788004.1 and U62540.1. On Nov 23, 2018 this sequence version replaced NM_004304.4. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU788003.1, AB209477.4 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000389048.8/ ENSP00000373700.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGAGCCA TCGGGCTCCT GTGGCTCCTG CCGCTGCTGC TTTCCACGGC AGCTGTGGGC 
TCCGGGATGG GGACCGGCCA GCGCGCGGGC TCCCCAGCTG CGGGGCCGCC GCTGCAGCCC 
CGGGAGCCAC TCAGCTACTC GCGCCTGCAG AGGAAGAGTC TGGCAGTTGA CTTCGTGGTG 
CCCTCGCTCT TCCGTGTCTA CGCCCGGGAC CTACTGCTGC CACCATCCTC CTCGGAGCTG 
AAGGCTGGCA GGCCCGAGGC CCGCGGCTCG CTAGCTCTGG ACTGCGCCCC GCTGCTCAGG 
TTGCTGGGGC CGGCGCCGGG GGTCTCCTGG ACCGCCGGTT CACCAGCCCC GGCAGAGGCC 
CGGACGCTGT CCAGGGTGCT GAAGGGCGGC TCCGTGCGCA AGCTCCGGCG TGCCAAGCAG 
TTGGTGCTGG AGCTGGGCGA GGAGGCGATC TTGGAGGGTT GCGTCGGGCC CCCCGGGGAG 
GCGGCTGTGG GGCTGCTCCA GTTCAATCTC AGCGAGCTGT TCAGTTGGTG GATTCGCCAA 
GGCGAAGGGC GACTGAGGAT CCGCCTGATG CCCGAGAAGA AGGCGTCGGA AGTGGGCAGA 
GAGGGAAGGC TGTCCGCGGC AATTCGCGCC TCCCAGCCCC GCCTTCTCTT CCAGATCTTC 
GGGACTGGTC ATAGCTCCTT GGAATCACCA ACAAACATGC CTTCTCCTTC TCCTGATTAT 
TTTACATGGA ATCTCACCTG GATAATGAAA GACTCCTTCC CTTTCCTGTC TCATCGCAGC 
CGATATGGTC TGGAGTGCAG CTTTGACTTC CCCTGTGAGC TGGAGTATTC CCCTCCACTG 
CATGACCTCA GGAACCAGAG CTGGTCCTGG CGCCGCATCC CCTCCGAGGA GGCCTCCCAG 
ATGGACTTGC TGGATGGGCC TGGGGCAGAG CGTTCTAAGG AGATGCCCAG AGGCTCCTTT 
CTCCTTCTCA ACACCTCAGC TGACTCCAAG CACACCATCC TGAGTCCGTG GATGAGGAGC 
AGCAGTGAGC ACTGCACACT GGCCGTCTCG GTGCACAGGC ACCTGCAGCC CTCTGGAAGG 
TACATTGCCC AGCTGCTGCC CCACAACGAG GCTGCAAGAG AGATCCTCCT GATGCCCACT 
CCAGGGAAGC ATGGTTGGAC AGTGCTCCAG GGAAGAATCG GGCGTCCAGA CAACCCATTT 
CGAGTGGCCC TGGAATACAT CTCCAGTGGA AACCGCAGCT TGTCTGCAGT GGACTTCTTT 
GCCCTGAAGA ACTGCAGTGA AGGAACATCC CCAGGCTCCA AGATGGCCCT GCAGAGCTCC 
TTCACTTGTT GGAATGGGAC AGTCCTCCAG CTTGGGCAGG CCTGTGACTT CCACCAGGAC 
TGTGCCCAGG GAGAAGATGA GAGCCAGATG TGCCGGAAAC TGCCTGTGGG TTTTTACTGC 
AACTTTGAAG ATGGCTTCTG TGGCTGGACC CAAGGCACAC TGTCACCCCA CACTCCTCAA 
TGGCAGGTCA GGACCCTAAA GGATGCCCGG TTCCAGGACC ACCAAGACCA TGCTCTATTG 
CTCAGTACCA CTGATGTCCC CGCTTCTGAA AGTGCTACAG TGACCAGTGC TACGTTTCCT 
GCACCGATCA AGAGCTCTCC ATGTGAGCTC CGAATGTCCT GGCTCATTCG TGGAGTCTTG 
AGGGGAAACG TGTCCTTGGT GCTAGTGGAG AACAAAACCG GGAAGGAGCA AGGCAGGATG 
GTCTGGCATG TCGCCGCCTA TGAAGGCTTG AGCCTGTGGC AGTGGATGGT GTTGCCTCTC 
CTCGATGTGT CTGACAGGTT CTGGCTGCAG ATGGTCGCAT GGTGGGGACA AGGATCCAGA 
GCCATCGTGG CTTTTGACAA TATCTCCATC AGCCTGGACT GCTACCTCAC CATTAGCGGA 
GAGGACAAGA TCCTGCAGAA TACAGCACCC AAATCAAGAA ACCTGTTTGA GAGAAACCCA 
AACAAGGAGC TGAAACCCGG GGAAAATTCA CCAAGACAGA CCCCCATCTT TGACCCTACA 
GTTCATTGGC TGTTCACCAC ATGTGGGGCC AGCGGGCCCC ATGGCCCCAC CCAGGCACAG 
TGCAACAACG CCTACCAGAA CTCCAACCTG AGCGTGGAGG TGGGGAGCGA GGGCCCCCTG 
AAAGGCATCC AGATCTGGAA GGTGCCAGCC ACCGACACCT ACAGCATCTC GGGCTACGGA 
GCTGCTGGCG GGAAAGGCGG GAAGAACACC ATGATGCGGT CCCACGGCGT GTCTGTGCTG 
GGCATCTTCA ACCTGGAGAA GGATGACATG CTGTACATCC TGGTTGGGCA GCAGGGAGAG 
GACGCCTGCC CCAGTACAAA CCAGTTAATC CAGAAAGTCT GCATTGGAGA GAACAATGTG 
ATAGAAGAAG AAATCCGTGT GAACAGAAGC GTGCATGAGT GGGCAGGAGG CGGAGGAGGA 
GGGGGTGGAG CCACCTACGT ATTTAAGATG AAGGATGGAG TGCCGGTGCC CCTGATCATT 
GCAGCCGGAG GTGGTGGCAG GGCCTACGGG GCCAAGACAG ACACGTTCCA CCCAGAGAGA 
CTGGAGAATA ACTCCTCGGT TCTAGGGCTA AACGGCAATT CCGGAGCCGC AGGTGGTGGA 
GGTGGCTGGA ATGATAACAC TTCCTTGCTC TGGGCCGGAA AATCTTTGCA GGAGGGTGCC 
ACCGGAGGAC ATTCCTGCCC CCAGGCCATG AAGAAGTGGG GGTGGGAGAC AAGAGGGGGT 
TTCGGAGGGG GTGGAGGGGG GTGCTCCTCA GGTGGAGGAG GCGGAGGATA TATAGGCGGC 
AATGCAGCCT CAAACAATGA CCCCGAAATG GATGGGGAAG ATGGGGTTTC CTTCATCAGT 
CCACTGGGCA TCCTGTACAC CCCAGCTTTA AAAGTGATGG AAGGCCACGG GGAAGTGAAT 
ATTAAGCATT ATCTAAACTG CAGTCACTGT GAGGTAGACG AATGTCACAT GGACCCTGAA 
AGCCACAAGG TCATCTGCTT CTGTGACCAC GGGACGGTGC TGGCTGAGGA TGGCGTCTCC 
TGCATTGTGT CACCCACCCC GGAGCCACAC CTGCCACTCT CGCTGATCCT CTCTGTGGTG 
ACCTCTGCCC TCGTGGCCGC CCTGGTCCTG GCTTTCTCCG GCATCATGAT TGTGTACCGC 
CGGAAGCACC AGGAGCTGCA AGCCATGCAG ATGGAGCTGC AGAGCCCTGA GTACAAGCTG 
AGCAAGCTCC GCACCTCGAC CATCATGACC GACTACAACC CCAACTACTG CTTTGCTGGC 
AAGACCTCCT CCATCAGTGA CCTGAAGGAG GTGCCGCGGA AAAACATCAC CCTCATTCGG 
GGTCTGGGCC ATGGCGCCTT TGGGGAGGTG TATGAAGGCC AGGTGTCCGG AATGCCCAAC 
GACCCAAGCC CCCTGCAAGT GGCTGTGAAG ACGCTGCCTG AAGTGTGCTC TGAACAGGAC 
GAACTGGATT TCCTCATGGA AGCCCTGATC ATCAGCAAAT TCAACCACCA GAACATTGTT 
CGCTGCATTG GGGTGAGCCT GCAATCCCTG CCCCGGTTCA TCCTGCTGGA GCTCATGGCG 
GGGGGAGACC TCAAGTCCTT CCTCCGAGAG ACCCGCCCTC GCCCGAGCCA GCCCTCCTCC 
CTGGCCATGC TGGACCTTCT GCACGTGGCT CGGGACATTG CCTGTGGCTG TCAGTATTTG 
GAGGAAAACC ACTTCATCCA CCGAGACATT GCTGCCAGAA ACTGCCTCTT GACCTGTCCA 
GGCCCTGGAA GAGTGGCCAA GATTGGAGAC TTCGGGATGG CCCGAGACAT CTACAGGGCG 
AGCTACTATA GAAAGGGAGG CTGTGCCATG CTGCCAGTTA AGTGGATGCC CCCAGAGGCC 
TTCATGGAAG GAATATTCAC TTCTAAAACA GACACATGGT CCTTTGGAGT GCTGCTATGG 
GAAATCTTTT CTCTTGGATA TATGCCATAC CCCAGCAAAA GCAACCAGGA AGTTCTGGAG 
TTTGTCACCA GTGGAGGCCG GATGGACCCA CCCAAGAACT GCCCTGGGCC TGTATACCGG 
ATAATGACTC AGTGCTGGCA ACATCAGCCT GAAGACAGGC CCAACTTTGC CATCATTTTG 
GAGAGGATTG AATACTGCAC CCAGGACCCG GATGTAATCA ACACCGCTTT GCCGATAGAA 
TATGGTCCAC TTGTGGAAGA GGAAGAGAAA GTGCCTGTGA GGCCCAAGGA CCCTGAGGGG 
GTTCCTCCTC TCCTGGTCTC TCAACAGGCA AAACGGGAGG AGGAGCGCAG CCCAGCTGCC 
CCACCACCTC TGCCTACCAC CTCCTCTGGC AAGGCTGCAA AGAAACCCAC AGCTGCAGAG 
ATCTCTGTTC GAGTCCCTAG AGGGCCGGCC GTGGAAGGGG GACACGTGAA TATGGCATTC 
TCTCAGTCCA ACCCTCCTTC GGAGTTGCAC AAGGTCCACG GATCCAGAAA CAAGCCCACC 
AGCTTGTGGA ACCCAACGTA CGGCTCCTGG TTTACAGAGA AACCCACCAA AAAGAATAAT 
CCTATAGCAA AGAAGGAGCC ACACGACAGG GGTAACCTGG GGCTGGAGGG AAGCTGTACT 
GTCCCACCTA ACGTTGCAAC TGGGAGACTT CCGGGGGCCT CACTGCTCCT AGAGCCCTCT 
TCGCTGACTG CCAATATGAA GGAGGTACCT CTGTTCAGGC TACGTCACTT CCCTTGTGGG 
AATGTCAATT ACGGCTACCA GCAACAGGGC TTGCCCTTAG AAGCCGCTAC TGCCCCTGGA 
GCTGGTCATT ACGAGGATAC CATTCTGAAA AGCAAGAATA GCATGAACCA GCCTGGGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004295.2
CDS	928..5790
Translation	MGAIGLLWLLPLLLSTAAVGSGMGTGQRAGSPAAGPPLQPREPLSYSRLQRKSLAVDFVVPSLFRVYARDLLLPPSSSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPAPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPGEAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQIFGTGHSSLESPTNMPSPSPDYFTWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRIPSEEASQMDLLDGPGAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGWTQGTLSPHTPQWQVRTLKDARFQDHQDHALLLSTTDVPASESATVTSATFPAPIKSSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKILQNTAPKSRNLFERNPNKELKPGENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP

Target ORF information:

RefSeq Version	NM_004304.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004304.5

ORF Insert Sequence:

ATGGGAGCCA TCGGGCTCCT GTGGCTCCTG CCGCTGCTGC TTTCCACGGC AGCTGTGGGC 
TCCGGGATGG GGACCGGCCA GCGCGCGGGC TCCCCAGCTG CGGGGCCGCC GCTGCAGCCC 
CGGGAGCCAC TCAGCTACTC GCGCCTGCAG AGGAAGAGTC TGGCAGTTGA CTTCGTGGTG 
CCCTCGCTCT TCCGTGTCTA CGCCCGGGAC CTACTGCTGC CACCATCCTC CTCGGAGCTG 
AAGGCTGGCA GGCCCGAGGC CCGCGGCTCG CTAGCTCTGG ACTGCGCCCC GCTGCTCAGG 
TTGCTGGGGC CGGCGCCGGG GGTCTCCTGG ACCGCCGGTT CACCAGCCCC GGCAGAGGCC 
CGGACGCTGT CCAGGGTGCT GAAGGGCGGC TCCGTGCGCA AGCTCCGGCG TGCCAAGCAG 
TTGGTGCTGG AGCTGGGCGA GGAGGCGATC TTGGAGGGTT GCGTCGGGCC CCCCGGGGAG 
GCGGCTGTGG GGCTGCTCCA GTTCAATCTC AGCGAGCTGT TCAGTTGGTG GATTCGCCAA 
GGCGAAGGGC GACTGAGGAT CCGCCTGATG CCCGAGAAGA AGGCGTCGGA AGTGGGCAGA 
GAGGGAAGGC TGTCCGCGGC AATTCGCGCC TCCCAGCCCC GCCTTCTCTT CCAGATCTTC 
GGGACTGGTC ATAGCTCCTT GGAATCACCA ACAAACATGC CTTCTCCTTC TCCTGATTAT 
TTTACATGGA ATCTCACCTG GATAATGAAA GACTCCTTCC CTTTCCTGTC TCATCGCAGC 
CGATATGGTC TGGAGTGCAG CTTTGACTTC CCCTGTGAGC TGGAGTATTC CCCTCCACTG 
CATGACCTCA GGAACCAGAG CTGGTCCTGG CGCCGCATCC CCTCCGAGGA GGCCTCCCAG 
ATGGACTTGC TGGATGGGCC TGGGGCAGAG CGTTCTAAGG AGATGCCCAG AGGCTCCTTT 
CTCCTTCTCA ACACCTCAGC TGACTCCAAG CACACCATCC TGAGTCCGTG GATGAGGAGC 
AGCAGTGAGC ACTGCACACT GGCCGTCTCG GTGCACAGGC ACCTGCAGCC CTCTGGAAGG 
TACATTGCCC AGCTGCTGCC CCACAACGAG GCTGCAAGAG AGATCCTCCT GATGCCCACT 
CCAGGGAAGC ATGGTTGGAC AGTGCTCCAG GGAAGAATCG GGCGTCCAGA CAACCCATTT 
CGAGTGGCCC TGGAATACAT CTCCAGTGGA AACCGCAGCT TGTCTGCAGT GGACTTCTTT 
GCCCTGAAGA ACTGCAGTGA AGGAACATCC CCAGGCTCCA AGATGGCCCT GCAGAGCTCC 
TTCACTTGTT GGAATGGGAC AGTCCTCCAG CTTGGGCAGG CCTGTGACTT CCACCAGGAC 
TGTGCCCAGG GAGAAGATGA GAGCCAGATG TGCCGGAAAC TGCCTGTGGG TTTTTACTGC 
AACTTTGAAG ATGGCTTCTG TGGCTGGACC CAAGGCACAC TGTCACCCCA CACTCCTCAA 
TGGCAGGTCA GGACCCTAAA GGATGCCCGG TTCCAGGACC ACCAAGACCA TGCTCTATTG 
CTCAGTACCA CTGATGTCCC CGCTTCTGAA AGTGCTACAG TGACCAGTGC TACGTTTCCT 
GCACCGATCA AGAGCTCTCC ATGTGAGCTC CGAATGTCCT GGCTCATTCG TGGAGTCTTG 
AGGGGAAACG TGTCCTTGGT GCTAGTGGAG AACAAAACCG GGAAGGAGCA AGGCAGGATG 
GTCTGGCATG TCGCCGCCTA TGAAGGCTTG AGCCTGTGGC AGTGGATGGT GTTGCCTCTC 
CTCGATGTGT CTGACAGGTT CTGGCTGCAG ATGGTCGCAT GGTGGGGACA AGGATCCAGA 
GCCATCGTGG CTTTTGACAA TATCTCCATC AGCCTGGACT GCTACCTCAC CATTAGCGGA 
GAGGACAAGA TCCTGCAGAA TACAGCACCC AAATCAAGAA ACCTGTTTGA GAGAAACCCA 
AACAAGGAGC TGAAACCCGG GGAAAATTCA CCAAGACAGA CCCCCATCTT TGACCCTACA 
GTTCATTGGC TGTTCACCAC ATGTGGGGCC AGCGGGCCCC ATGGCCCCAC CCAGGCACAG 
TGCAACAACG CCTACCAGAA CTCCAACCTG AGCGTGGAGG TGGGGAGCGA GGGCCCCCTG 
AAAGGCATCC AGATCTGGAA GGTGCCAGCC ACCGACACCT ACAGCATCTC GGGCTACGGA 
GCTGCTGGCG GGAAAGGCGG GAAGAACACC ATGATGCGGT CCCACGGCGT GTCTGTGCTG 
GGCATCTTCA ACCTGGAGAA GGATGACATG CTGTACATCC TGGTTGGGCA GCAGGGAGAG 
GACGCCTGCC CCAGTACAAA CCAGTTAATC CAGAAAGTCT GCATTGGAGA GAACAATGTG 
ATAGAAGAAG AAATCCGTGT GAACAGAAGC GTGCATGAGT GGGCAGGAGG CGGAGGAGGA 
GGGGGTGGAG CCACCTACGT ATTTAAGATG AAGGATGGAG TGCCGGTGCC CCTGATCATT 
GCAGCCGGAG GTGGTGGCAG GGCCTACGGG GCCAAGACAG ACACGTTCCA CCCAGAGAGA 
CTGGAGAATA ACTCCTCGGT TCTAGGGCTA AACGGCAATT CCGGAGCCGC AGGTGGTGGA 
GGTGGCTGGA ATGATAACAC TTCCTTGCTC TGGGCCGGAA AATCTTTGCA GGAGGGTGCC 
ACCGGAGGAC ATTCCTGCCC CCAGGCCATG AAGAAGTGGG GGTGGGAGAC AAGAGGGGGT 
TTCGGAGGGG GTGGAGGGGG GTGCTCCTCA GGTGGAGGAG GCGGAGGATA TATAGGCGGC 
AATGCAGCCT CAAACAATGA CCCCGAAATG GATGGGGAAG ATGGGGTTTC CTTCATCAGT 
CCACTGGGCA TCCTGTACAC CCCAGCTTTA AAAGTGATGG AAGGCCACGG GGAAGTGAAT 
ATTAAGCATT ATCTAAACTG CAGTCACTGT GAGGTAGACG AATGTCACAT GGACCCTGAA 
AGCCACAAGG TCATCTGCTT CTGTGACCAC GGGACGGTGC TGGCTGAGGA TGGCGTCTCC 
TGCATTGTGT CACCCACCCC GGAGCCACAC CTGCCACTCT CGCTGATCCT CTCTGTGGTG 
ACCTCTGCCC TCGTGGCCGC CCTGGTCCTG GCTTTCTCCG GCATCATGAT TGTGTACCGC 
CGGAAGCACC AGGAGCTGCA AGCCATGCAG ATGGAGCTGC AGAGCCCTGA GTACAAGCTG 
AGCAAGCTCC GCACCTCGAC CATCATGACC GACTACAACC CCAACTACTG CTTTGCTGGC 
AAGACCTCCT CCATCAGTGA CCTGAAGGAG GTGCCGCGGA AAAACATCAC CCTCATTCGG 
GGTCTGGGCC ATGGCGCCTT TGGGGAGGTG TATGAAGGCC AGGTGTCCGG AATGCCCAAC 
GACCCAAGCC CCCTGCAAGT GGCTGTGAAG ACGCTGCCTG AAGTGTGCTC TGAACAGGAC 
GAACTGGATT TCCTCATGGA AGCCCTGATC ATCAGCAAAT TCAACCACCA GAACATTGTT 
CGCTGCATTG GGGTGAGCCT GCAATCCCTG CCCCGGTTCA TCCTGCTGGA GCTCATGGCG 
GGGGGAGACC TCAAGTCCTT CCTCCGAGAG ACCCGCCCTC GCCCGAGCCA GCCCTCCTCC 
CTGGCCATGC TGGACCTTCT GCACGTGGCT CGGGACATTG CCTGTGGCTG TCAGTATTTG 
GAGGAAAACC ACTTCATCCA CCGAGACATT GCTGCCAGAA ACTGCCTCTT GACCTGTCCA 
GGCCCTGGAA GAGTGGCCAA GATTGGAGAC TTCGGGATGG CCCGAGACAT CTACAGGGCG 
AGCTACTATA GAAAGGGAGG CTGTGCCATG CTGCCAGTTA AGTGGATGCC CCCAGAGGCC 
TTCATGGAAG GAATATTCAC TTCTAAAACA GACACATGGT CCTTTGGAGT GCTGCTATGG 
GAAATCTTTT CTCTTGGATA TATGCCATAC CCCAGCAAAA GCAACCAGGA AGTTCTGGAG 
TTTGTCACCA GTGGAGGCCG GATGGACCCA CCCAAGAACT GCCCTGGGCC TGTATACCGG 
ATAATGACTC AGTGCTGGCA ACATCAGCCT GAAGACAGGC CCAACTTTGC CATCATTTTG 
GAGAGGATTG AATACTGCAC CCAGGACCCG GATGTAATCA ACACCGCTTT GCCGATAGAA 
TATGGTCCAC TTGTGGAAGA GGAAGAGAAA GTGCCTGTGA GGCCCAAGGA CCCTGAGGGG 
GTTCCTCCTC TCCTGGTCTC TCAACAGGCA AAACGGGAGG AGGAGCGCAG CCCAGCTGCC 
CCACCACCTC TGCCTACCAC CTCCTCTGGC AAGGCTGCAA AGAAACCCAC AGCTGCAGAG 
ATCTCTGTTC GAGTCCCTAG AGGGCCGGCC GTGGAAGGGG GACACGTGAA TATGGCATTC 
TCTCAGTCCA ACCCTCCTTC GGAGTTGCAC AAGGTCCACG GATCCAGAAA CAAGCCCACC 
AGCTTGTGGA ACCCAACGTA CGGCTCCTGG TTTACAGAGA AACCCACCAA AAAGAATAAT 
CCTATAGCAA AGAAGGAGCC ACACGACAGG GGTAACCTGG GGCTGGAGGG AAGCTGTACT 
GTCCCACCTA ACGTTGCAAC TGGGAGACTT CCGGGGGCCT CACTGCTCCT AGAGCCCTCT 
TCGCTGACTG CCAATATGAA GGAGGTACCT CTGTTCAGGC TACGTCACTT CCCTTGTGGG 
AATGTCAATT ACGGCTACCA GCAACAGGGC TTGCCCTTAG AAGCCGCTAC TGCCCCTGGA 
GCTGGTCATT ACGAGGATAC CATTCTGAAA AGCAAGAATA GCATGAACCA GCCTGGGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALK ( NM_001353765.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001340694.1 Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu102985
Clone ID Related Accession (Same CDS sequence)	XM_024452779.1 , NM_001353765.1
Accession Version	NM_001353765.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1659bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	ALK tyrosine kinase receptor isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from LN864494.1. Transcript Variant: This variant (2) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. The promoter and 5' terminal exon sequence is from an endogenous retroviral LTR (PMID: 26444240). The resulting isoform (2, also known as ALKATI) is shorter and has a distinct N-terminus, compared to isoform 1. The encoded protein is expressed in melanoma cells. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: LN864494.1, KF360988.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGATGG AGCTGCAGAG CCCTGAGTAC AAGCTGAGCA AGCTCCGCAC CTCGACCATC 
ATGACCGACT ACAACCCCAA CTACTGCTTT GCTGGCAAGA CCTCCTCCAT CAGTGACCTG 
AAGGAGGTGC CGCGGAAAAA CATCACCCTC ATTCGGGGTC TGGGCCATGG CGCCTTTGGG 
GAGGTGTATG AAGGCCAGGT GTCCGGAATG CCCAACGACC CAAGCCCCCT GCAAGTGGCT 
GTGAAGACGC TGCCTGAAGT GTGCTCTGAA CAGGACGAAC TGGATTTCCT CATGGAAGCC 
CTGATCATCA GCAAATTCAA CCACCAGAAC ATTGTTCGCT GCATTGGGGT GAGCCTGCAA 
TCCCTGCCCC GGTTCATCCT GCTGGAGCTC ATGGCGGGGG GAGACCTCAA GTCCTTCCTC 
CGAGAGACCC GCCCTCGCCC GAGCCAGCCC TCCTCCCTGG CCATGCTGGA CCTTCTGCAC 
GTGGCTCGGG ACATTGCCTG TGGCTGTCAG TATTTGGAGG AAAACCACTT CATCCACCGA 
GACATTGCTG CCAGAAACTG CCTCTTGACC TGTCCAGGCC CTGGAAGAGT GGCCAAGATT 
GGAGACTTCG GGATGGCCCG AGACATCTAC AGGGCGAGCT ACTATAGAAA GGGAGGCTGT 
GCCATGCTGC CAGTTAAGTG GATGCCCCCA GAGGCCTTCA TGGAAGGAAT ATTCACTTCT 
AAAACAGACA CATGGTCCTT TGGAGTGCTG CTATGGGAAA TCTTTTCTCT TGGATATATG 
CCATACCCCA GCAAAAGCAA CCAGGAAGTT CTGGAGTTTG TCACCAGTGG AGGCCGGATG 
GACCCACCCA AGAACTGCCC TGGGCCTGTA TACCGGATAA TGACTCAGTG CTGGCAACAT 
CAGCCTGAAG ACAGGCCCAA CTTTGCCATC ATTTTGGAGA GGATTGAATA CTGCACCCAG 
GACCCGGATG TAATCAACAC CGCTTTGCCG ATAGAATATG GTCCACTTGT GGAAGAGGAA 
GAGAAAGTGC CTGTGAGGCC CAAGGACCCT GAGGGGGTTC CTCCTCTCCT GGTCTCTCAA 
CAGGCAAAAC GGGAGGAGGA GCGCAGCCCA GCTGCCCCAC CACCTCTGCC TACCACCTCC 
TCTGGCAAGG CTGCAAAGAA ACCCACAGCT GCAGAGATCT CTGTTCGAGT CCCTAGAGGG 
CCGGCCGTGG AAGGGGGACA CGTGAATATG GCATTCTCTC AGTCCAACCC TCCTTCGGAG 
TTGCACAAGG TCCACGGATC CAGAAACAAG CCCACCAGCT TGTGGAACCC AACGTACGGC 
TCCTGGTTTA CAGAGAAACC CACCAAAAAG AATAATCCTA TAGCAAAGAA GGAGCCACAC 
GACAGGGGTA ACCTGGGGCT GGAGGGAAGC TGTACTGTCC CACCTAACGT TGCAACTGGG 
AGACTTCCGG GGGCCTCACT GCTCCTAGAG CCCTCTTCGC TGACTGCCAA TATGAAGGAG 
GTACCTCTGT TCAGGCTACG TCACTTCCCT TGTGGGAATG TCAATTACGG CTACCAGCAA 
CAGGGCTTGC CCTTAGAAGC CGCTACTGCC CCTGGAGCTG GTCATTACGA GGATACCATT 
CTGAAAAGCA AGAATAGCAT GAACCAGCCT GGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001340694.1
CDS	405..2063
Translation	MQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP

Target ORF information:

RefSeq Version	NM_001353765.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001353765.1

ORF Insert Sequence:

ATGCAGATGG AGCTGCAGAG CCCTGAGTAC AAGCTGAGCA AGCTCCGCAC CTCGACCATC 
ATGACCGACT ACAACCCCAA CTACTGCTTT GCTGGCAAGA CCTCCTCCAT CAGTGACCTG 
AAGGAGGTGC CGCGGAAAAA CATCACCCTC ATTCGGGGTC TGGGCCATGG CGCCTTTGGG 
GAGGTGTATG AAGGCCAGGT GTCCGGAATG CCCAACGACC CAAGCCCCCT GCAAGTGGCT 
GTGAAGACGC TGCCTGAAGT GTGCTCTGAA CAGGACGAAC TGGATTTCCT CATGGAAGCC 
CTGATCATCA GCAAATTCAA CCACCAGAAC ATTGTTCGCT GCATTGGGGT GAGCCTGCAA 
TCCCTGCCCC GGTTCATCCT GCTGGAGCTC ATGGCGGGGG GAGACCTCAA GTCCTTCCTC 
CGAGAGACCC GCCCTCGCCC GAGCCAGCCC TCCTCCCTGG CCATGCTGGA CCTTCTGCAC 
GTGGCTCGGG ACATTGCCTG TGGCTGTCAG TATTTGGAGG AAAACCACTT CATCCACCGA 
GACATTGCTG CCAGAAACTG CCTCTTGACC TGTCCAGGCC CTGGAAGAGT GGCCAAGATT 
GGAGACTTCG GGATGGCCCG AGACATCTAC AGGGCGAGCT ACTATAGAAA GGGAGGCTGT 
GCCATGCTGC CAGTTAAGTG GATGCCCCCA GAGGCCTTCA TGGAAGGAAT ATTCACTTCT 
AAAACAGACA CATGGTCCTT TGGAGTGCTG CTATGGGAAA TCTTTTCTCT TGGATATATG 
CCATACCCCA GCAAAAGCAA CCAGGAAGTT CTGGAGTTTG TCACCAGTGG AGGCCGGATG 
GACCCACCCA AGAACTGCCC TGGGCCTGTA TACCGGATAA TGACTCAGTG CTGGCAACAT 
CAGCCTGAAG ACAGGCCCAA CTTTGCCATC ATTTTGGAGA GGATTGAATA CTGCACCCAG 
GACCCGGATG TAATCAACAC CGCTTTGCCG ATAGAATATG GTCCACTTGT GGAAGAGGAA 
GAGAAAGTGC CTGTGAGGCC CAAGGACCCT GAGGGGGTTC CTCCTCTCCT GGTCTCTCAA 
CAGGCAAAAC GGGAGGAGGA GCGCAGCCCA GCTGCCCCAC CACCTCTGCC TACCACCTCC 
TCTGGCAAGG CTGCAAAGAA ACCCACAGCT GCAGAGATCT CTGTTCGAGT CCCTAGAGGG 
CCGGCCGTGG AAGGGGGACA CGTGAATATG GCATTCTCTC AGTCCAACCC TCCTTCGGAG 
TTGCACAAGG TCCACGGATC CAGAAACAAG CCCACCAGCT TGTGGAACCC AACGTACGGC 
TCCTGGTTTA CAGAGAAACC CACCAAAAAG AATAATCCTA TAGCAAAGAA GGAGCCACAC 
GACAGGGGTA ACCTGGGGCT GGAGGGAAGC TGTACTGTCC CACCTAACGT TGCAACTGGG 
AGACTTCCGG GGGCCTCACT GCTCCTAGAG CCCTCTTCGC TGACTGCCAA TATGAAGGAG 
GTACCTCTGT TCAGGCTACG TCACTTCCCT TGTGGGAATG TCAATTACGG CTACCAGCAA 
CAGGGCTTGC CCTTAGAAGC CGCTACTGCC CCTGGAGCTG GTCATTACGA GGATACCATT 
CTGAAAAGCA AGAATAGCAT GAACCAGCCT GGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALK ( XM_024452779.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308547.1 Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant X3, mRNA.

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CloneID	OHu102985
Clone ID Related Accession (Same CDS sequence)	XM_024452779.1 , NM_001353765.1
Accession Version	XM_024452779.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1659bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ALK tyrosine kinase receptor isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGATGG AGCTGCAGAG CCCTGAGTAC AAGCTGAGCA AGCTCCGCAC CTCGACCATC 
ATGACCGACT ACAACCCCAA CTACTGCTTT GCTGGCAAGA CCTCCTCCAT CAGTGACCTG 
AAGGAGGTGC CGCGGAAAAA CATCACCCTC ATTCGGGGTC TGGGCCATGG CGCCTTTGGG 
GAGGTGTATG AAGGCCAGGT GTCCGGAATG CCCAACGACC CAAGCCCCCT GCAAGTGGCT 
GTGAAGACGC TGCCTGAAGT GTGCTCTGAA CAGGACGAAC TGGATTTCCT CATGGAAGCC 
CTGATCATCA GCAAATTCAA CCACCAGAAC ATTGTTCGCT GCATTGGGGT GAGCCTGCAA 
TCCCTGCCCC GGTTCATCCT GCTGGAGCTC ATGGCGGGGG GAGACCTCAA GTCCTTCCTC 
CGAGAGACCC GCCCTCGCCC GAGCCAGCCC TCCTCCCTGG CCATGCTGGA CCTTCTGCAC 
GTGGCTCGGG ACATTGCCTG TGGCTGTCAG TATTTGGAGG AAAACCACTT CATCCACCGA 
GACATTGCTG CCAGAAACTG CCTCTTGACC TGTCCAGGCC CTGGAAGAGT GGCCAAGATT 
GGAGACTTCG GGATGGCCCG AGACATCTAC AGGGCGAGCT ACTATAGAAA GGGAGGCTGT 
GCCATGCTGC CAGTTAAGTG GATGCCCCCA GAGGCCTTCA TGGAAGGAAT ATTCACTTCT 
AAAACAGACA CATGGTCCTT TGGAGTGCTG CTATGGGAAA TCTTTTCTCT TGGATATATG 
CCATACCCCA GCAAAAGCAA CCAGGAAGTT CTGGAGTTTG TCACCAGTGG AGGCCGGATG 
GACCCACCCA AGAACTGCCC TGGGCCTGTA TACCGGATAA TGACTCAGTG CTGGCAACAT 
CAGCCTGAAG ACAGGCCCAA CTTTGCCATC ATTTTGGAGA GGATTGAATA CTGCACCCAG 
GACCCGGATG TAATCAACAC CGCTTTGCCG ATAGAATATG GTCCACTTGT GGAAGAGGAA 
GAGAAAGTGC CTGTGAGGCC CAAGGACCCT GAGGGGGTTC CTCCTCTCCT GGTCTCTCAA 
CAGGCAAAAC GGGAGGAGGA GCGCAGCCCA GCTGCCCCAC CACCTCTGCC TACCACCTCC 
TCTGGCAAGG CTGCAAAGAA ACCCACAGCT GCAGAGATCT CTGTTCGAGT CCCTAGAGGG 
CCGGCCGTGG AAGGGGGACA CGTGAATATG GCATTCTCTC AGTCCAACCC TCCTTCGGAG 
TTGCACAAGG TCCACGGATC CAGAAACAAG CCCACCAGCT TGTGGAACCC AACGTACGGC 
TCCTGGTTTA CAGAGAAACC CACCAAAAAG AATAATCCTA TAGCAAAGAA GGAGCCACAC 
GACAGGGGTA ACCTGGGGCT GGAGGGAAGC TGTACTGTCC CACCTAACGT TGCAACTGGG 
AGACTTCCGG GGGCCTCACT GCTCCTAGAG CCCTCTTCGC TGACTGCCAA TATGAAGGAG 
GTACCTCTGT TCAGGCTACG TCACTTCCCT TGTGGGAATG TCAATTACGG CTACCAGCAA 
CAGGGCTTGC CCTTAGAAGC CGCTACTGCC CCTGGAGCTG GTCATTACGA GGATACCATT 
CTGAAAAGCA AGAATAGCAT GAACCAGCCT GGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308547.1
CDS	1263..2921
Translation	MQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP

Target ORF information:

RefSeq Version	XM_024452779.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452779.1

ORF Insert Sequence:

ATGCAGATGG AGCTGCAGAG CCCTGAGTAC AAGCTGAGCA AGCTCCGCAC CTCGACCATC 
ATGACCGACT ACAACCCCAA CTACTGCTTT GCTGGCAAGA CCTCCTCCAT CAGTGACCTG 
AAGGAGGTGC CGCGGAAAAA CATCACCCTC ATTCGGGGTC TGGGCCATGG CGCCTTTGGG 
GAGGTGTATG AAGGCCAGGT GTCCGGAATG CCCAACGACC CAAGCCCCCT GCAAGTGGCT 
GTGAAGACGC TGCCTGAAGT GTGCTCTGAA CAGGACGAAC TGGATTTCCT CATGGAAGCC 
CTGATCATCA GCAAATTCAA CCACCAGAAC ATTGTTCGCT GCATTGGGGT GAGCCTGCAA 
TCCCTGCCCC GGTTCATCCT GCTGGAGCTC ATGGCGGGGG GAGACCTCAA GTCCTTCCTC 
CGAGAGACCC GCCCTCGCCC GAGCCAGCCC TCCTCCCTGG CCATGCTGGA CCTTCTGCAC 
GTGGCTCGGG ACATTGCCTG TGGCTGTCAG TATTTGGAGG AAAACCACTT CATCCACCGA 
GACATTGCTG CCAGAAACTG CCTCTTGACC TGTCCAGGCC CTGGAAGAGT GGCCAAGATT 
GGAGACTTCG GGATGGCCCG AGACATCTAC AGGGCGAGCT ACTATAGAAA GGGAGGCTGT 
GCCATGCTGC CAGTTAAGTG GATGCCCCCA GAGGCCTTCA TGGAAGGAAT ATTCACTTCT 
AAAACAGACA CATGGTCCTT TGGAGTGCTG CTATGGGAAA TCTTTTCTCT TGGATATATG 
CCATACCCCA GCAAAAGCAA CCAGGAAGTT CTGGAGTTTG TCACCAGTGG AGGCCGGATG 
GACCCACCCA AGAACTGCCC TGGGCCTGTA TACCGGATAA TGACTCAGTG CTGGCAACAT 
CAGCCTGAAG ACAGGCCCAA CTTTGCCATC ATTTTGGAGA GGATTGAATA CTGCACCCAG 
GACCCGGATG TAATCAACAC CGCTTTGCCG ATAGAATATG GTCCACTTGT GGAAGAGGAA 
GAGAAAGTGC CTGTGAGGCC CAAGGACCCT GAGGGGGTTC CTCCTCTCCT GGTCTCTCAA 
CAGGCAAAAC GGGAGGAGGA GCGCAGCCCA GCTGCCCCAC CACCTCTGCC TACCACCTCC 
TCTGGCAAGG CTGCAAAGAA ACCCACAGCT GCAGAGATCT CTGTTCGAGT CCCTAGAGGG 
CCGGCCGTGG AAGGGGGACA CGTGAATATG GCATTCTCTC AGTCCAACCC TCCTTCGGAG 
TTGCACAAGG TCCACGGATC CAGAAACAAG CCCACCAGCT TGTGGAACCC AACGTACGGC 
TCCTGGTTTA CAGAGAAACC CACCAAAAAG AATAATCCTA TAGCAAAGAA GGAGCCACAC 
GACAGGGGTA ACCTGGGGCT GGAGGGAAGC TGTACTGTCC CACCTAACGT TGCAACTGGG 
AGACTTCCGG GGGCCTCACT GCTCCTAGAG CCCTCTTCGC TGACTGCCAA TATGAAGGAG 
GTACCTCTGT TCAGGCTACG TCACTTCCCT TGTGGGAATG TCAATTACGG CTACCAGCAA 
CAGGGCTTGC CCTTAGAAGC CGCTACTGCC CCTGGAGCTG GTCATTACGA GGATACCATT 
CTGAAAAGCA AGAATAGCAT GAACCAGCCT GGGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALK ( XM_024452778.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308546.1 Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant X2, mRNA.

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CloneID	OHu104838
Clone ID Related Accession (Same CDS sequence)	XM_024452778.1
Accession Version	XM_024452778.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2016bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ALK tyrosine kinase receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGGGG AAGATGGGGT TTCCTTCATC AGTCCACTGG GCATCCTGTA CACCCCAGCT 
TTAAAAGTGA TGGAAGGCCA CGGGGAAGTG AATATTAAGC ATTATCTAAA CTGCAGTCAC 
TGTGAGGTAG ACGAATGTCA CATGGACCCT GAAAGCCACA AGGTCATCTG CTTCTGTGAC 
CACGGGACGG TGCTGGCTGA GGATGGCGTC TCCTGCATTG TGTCACCCAC CCCGGAGCCA 
CACCTGCCAC TCTCGCTGAT CCTCTCTGTG GTGACCTCTG CCCTCGTGGC CGCCCTGGTC 
CTGGCTTTCT CCGGCATCAT GATTGTGTAC CGCCGGAAGC ACCAGGAGCT GCAAGCCATG 
CAGATGGAGC TGCAGAGCCC TGAGTACAAG CTGAGCAAGC TCCGCACCTC GACCATCATG 
ACCGACTACA ACCCCAACTA CTGCTTTGCT GGCAAGACCT CCTCCATCAG TGACCTGAAG 
GAGGTGCCGC GGAAAAACAT CACCCTCATT CGGGGTCTGG GCCATGGCGC CTTTGGGGAG 
GTGTATGAAG GCCAGGTGTC CGGAATGCCC AACGACCCAA GCCCCCTGCA AGTGGCTGTG 
AAGACGCTGC CTGAAGTGTG CTCTGAACAG GACGAACTGG ATTTCCTCAT GGAAGCCCTG 
ATCATCAGCA AATTCAACCA CCAGAACATT GTTCGCTGCA TTGGGGTGAG CCTGCAATCC 
CTGCCCCGGT TCATCCTGCT GGAGCTCATG GCGGGGGGAG ACCTCAAGTC CTTCCTCCGA 
GAGACCCGCC CTCGCCCGAG CCAGCCCTCC TCCCTGGCCA TGCTGGACCT TCTGCACGTG 
GCTCGGGACA TTGCCTGTGG CTGTCAGTAT TTGGAGGAAA ACCACTTCAT CCACCGAGAC 
ATTGCTGCCA GAAACTGCCT CTTGACCTGT CCAGGCCCTG GAAGAGTGGC CAAGATTGGA 
GACTTCGGGA TGGCCCGAGA CATCTACAGG GCGAGCTACT ATAGAAAGGG AGGCTGTGCC 
ATGCTGCCAG TTAAGTGGAT GCCCCCAGAG GCCTTCATGG AAGGAATATT CACTTCTAAA 
ACAGACACAT GGTCCTTTGG AGTGCTGCTA TGGGAAATCT TTTCTCTTGG ATATATGCCA 
TACCCCAGCA AAAGCAACCA GGAAGTTCTG GAGTTTGTCA CCAGTGGAGG CCGGATGGAC 
CCACCCAAGA ACTGCCCTGG GCCTGTATAC CGGATAATGA CTCAGTGCTG GCAACATCAG 
CCTGAAGACA GGCCCAACTT TGCCATCATT TTGGAGAGGA TTGAATACTG CACCCAGGAC 
CCGGATGTAA TCAACACCGC TTTGCCGATA GAATATGGTC CACTTGTGGA AGAGGAAGAG 
AAAGTGCCTG TGAGGCCCAA GGACCCTGAG GGGGTTCCTC CTCTCCTGGT CTCTCAACAG 
GCAAAACGGG AGGAGGAGCG CAGCCCAGCT GCCCCACCAC CTCTGCCTAC CACCTCCTCT 
GGCAAGGCTG CAAAGAAACC CACAGCTGCA GAGATCTCTG TTCGAGTCCC TAGAGGGCCG 
GCCGTGGAAG GGGGACACGT GAATATGGCA TTCTCTCAGT CCAACCCTCC TTCGGAGTTG 
CACAAGGTCC ACGGATCCAG AAACAAGCCC ACCAGCTTGT GGAACCCAAC GTACGGCTCC 
TGGTTTACAG AGAAACCCAC CAAAAAGAAT AATCCTATAG CAAAGAAGGA GCCACACGAC 
AGGGGTAACC TGGGGCTGGA GGGAAGCTGT ACTGTCCCAC CTAACGTTGC AACTGGGAGA 
CTTCCGGGGG CCTCACTGCT CCTAGAGCCC TCTTCGCTGA CTGCCAATAT GAAGGAGGTA 
CCTCTGTTCA GGCTACGTCA CTTCCCTTGT GGGAATGTCA ATTACGGCTA CCAGCAACAG 
GGCTTGCCCT TAGAAGCCGC TACTGCCCCT GGAGCTGGTC ATTACGAGGA TACCATTCTG 
AAAAGCAAGA ATAGCATGAA CCAGCCTGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308546.1
CDS	170..2185
Translation	MDGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP

Target ORF information:

RefSeq Version	XM_024452778.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ALK receptor tyrosine kinase (ALK), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452778.1

ORF Insert Sequence:

ATGGATGGGG AAGATGGGGT TTCCTTCATC AGTCCACTGG GCATCCTGTA CACCCCAGCT 
TTAAAAGTGA TGGAAGGCCA CGGGGAAGTG AATATTAAGC ATTATCTAAA CTGCAGTCAC 
TGTGAGGTAG ACGAATGTCA CATGGACCCT GAAAGCCACA AGGTCATCTG CTTCTGTGAC 
CACGGGACGG TGCTGGCTGA GGATGGCGTC TCCTGCATTG TGTCACCCAC CCCGGAGCCA 
CACCTGCCAC TCTCGCTGAT CCTCTCTGTG GTGACCTCTG CCCTCGTGGC CGCCCTGGTC 
CTGGCTTTCT CCGGCATCAT GATTGTGTAC CGCCGGAAGC ACCAGGAGCT GCAAGCCATG 
CAGATGGAGC TGCAGAGCCC TGAGTACAAG CTGAGCAAGC TCCGCACCTC GACCATCATG 
ACCGACTACA ACCCCAACTA CTGCTTTGCT GGCAAGACCT CCTCCATCAG TGACCTGAAG 
GAGGTGCCGC GGAAAAACAT CACCCTCATT CGGGGTCTGG GCCATGGCGC CTTTGGGGAG 
GTGTATGAAG GCCAGGTGTC CGGAATGCCC AACGACCCAA GCCCCCTGCA AGTGGCTGTG 
AAGACGCTGC CTGAAGTGTG CTCTGAACAG GACGAACTGG ATTTCCTCAT GGAAGCCCTG 
ATCATCAGCA AATTCAACCA CCAGAACATT GTTCGCTGCA TTGGGGTGAG CCTGCAATCC 
CTGCCCCGGT TCATCCTGCT GGAGCTCATG GCGGGGGGAG ACCTCAAGTC CTTCCTCCGA 
GAGACCCGCC CTCGCCCGAG CCAGCCCTCC TCCCTGGCCA TGCTGGACCT TCTGCACGTG 
GCTCGGGACA TTGCCTGTGG CTGTCAGTAT TTGGAGGAAA ACCACTTCAT CCACCGAGAC 
ATTGCTGCCA GAAACTGCCT CTTGACCTGT CCAGGCCCTG GAAGAGTGGC CAAGATTGGA 
GACTTCGGGA TGGCCCGAGA CATCTACAGG GCGAGCTACT ATAGAAAGGG AGGCTGTGCC 
ATGCTGCCAG TTAAGTGGAT GCCCCCAGAG GCCTTCATGG AAGGAATATT CACTTCTAAA 
ACAGACACAT GGTCCTTTGG AGTGCTGCTA TGGGAAATCT TTTCTCTTGG ATATATGCCA 
TACCCCAGCA AAAGCAACCA GGAAGTTCTG GAGTTTGTCA CCAGTGGAGG CCGGATGGAC 
CCACCCAAGA ACTGCCCTGG GCCTGTATAC CGGATAATGA CTCAGTGCTG GCAACATCAG 
CCTGAAGACA GGCCCAACTT TGCCATCATT TTGGAGAGGA TTGAATACTG CACCCAGGAC 
CCGGATGTAA TCAACACCGC TTTGCCGATA GAATATGGTC CACTTGTGGA AGAGGAAGAG 
AAAGTGCCTG TGAGGCCCAA GGACCCTGAG GGGGTTCCTC CTCTCCTGGT CTCTCAACAG 
GCAAAACGGG AGGAGGAGCG CAGCCCAGCT GCCCCACCAC CTCTGCCTAC CACCTCCTCT 
GGCAAGGCTG CAAAGAAACC CACAGCTGCA GAGATCTCTG TTCGAGTCCC TAGAGGGCCG 
GCCGTGGAAG GGGGACACGT GAATATGGCA TTCTCTCAGT CCAACCCTCC TTCGGAGTTG 
CACAAGGTCC ACGGATCCAG AAACAAGCCC ACCAGCTTGT GGAACCCAAC GTACGGCTCC 
TGGTTTACAG AGAAACCCAC CAAAAAGAAT AATCCTATAG CAAAGAAGGA GCCACACGAC 
AGGGGTAACC TGGGGCTGGA GGGAAGCTGT ACTGTCCCAC CTAACGTTGC AACTGGGAGA 
CTTCCGGGGG CCTCACTGCT CCTAGAGCCC TCTTCGCTGA CTGCCAATAT GAAGGAGGTA 
CCTCTGTTCA GGCTACGTCA CTTCCCTTGT GGGAATGTCA ATTACGGCTA CCAGCAACAG 
GGCTTGCCCT TAGAAGCCGC TACTGCCCCT GGAGCTGGTC ATTACGAGGA TACCATTCTG 
AAAAGCAAGA ATAGCATGAA CCAGCCTGGG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Environmental tobacco smoke exposure and EGFR and ALK alterations in never smokers' lung cancer. Results from the LCRINS study.
Cancer letters411130-135(2017 Dec)
Torres-Dur?n M,Ruano-Ravina A,Kelsey KT,Parente-Lamelas I,Leiro-Fern?ndez V,Abdulkader I,Provencio M,Abal-Arca J,Castro-A??n O,Montero-Mart?nez C,Vidal-Garc?a I,Amenedo M,Golpe-G?mez A,Mart?nez C,Guzm?n-Taveras R,Mejuto-Mart? MJ,Fern?ndez-Villar A,Barros-Dios JM

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ALK cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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