GABARAPL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GABARAPL1
Entrez Gene ID	23710
Full Name	GABA type A receptor associated protein like 1
Synonyms	APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GEC1
General protein information	Preferred Names GABA type A receptor associated protein like 1 Names gamma-aminobutyric acid receptor-associated protein-like 1 GABA(A) receptor-associated protein-like 1 GABARAPL1-a GEC-1 early estrogen-regulated protein glandular epithelial cell protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.2
Disorder MIM:	607420

mRNA and Protein(s)

mRNA	Protein	Name
NM_001363598.1	NP_001350527.1	gamma-aminobutyric acid receptor-associated protein-like 1 isoform 1
XM_005253344.4	XP_005253401.1	gamma-aminobutyric acid receptor-associated protein-like 1 isoform X1
NM_031412.4	NP_113600.1	gamma-aminobutyric acid receptor-associated protein-like 1 isoform 2
NM_001363598.2	NP_001350527.1	gamma-aminobutyric acid receptor-associated protein-like 1 isoform 1
NM_031412.2	NP_113600.1	gamma-aminobutyric acid receptor-associated protein-like 1

Pathways from BioSystems

Homologies

	GABARAPL1	XP_001115102.1
Canis lupus familiaris (dog)	GABARAPL1	XP_005637218.1
Caenorhabditis elegans (roundworm)	lgg-1	NP_495277.1
Eremothecium gossypii	AGOS_AER396W	NP_985251.1
Homo sapiens (human)	GABARAPL1	NP_113600.1
Drosophila melanogaster (fruit fly)	Atg8a	NP_727447.1
Kluyveromyces lactis	KLLA0E20593g	XP_454881.1
Bos taurus (cattle)	GABARAPL1	NP_001028788.1
Mus musculus (house mouse)	Gabarapl1	NP_065615.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002685	XP_312238.3
Saccharomyces cerevisiae (baker's yeast)	ATG8	NP_009475.1
Schizosaccharomyces pombe (fission yeast)	atg8	NP_596531.1
Neurospora crassa	NCU01545	XP_956248.1
Arabidopsis thaliana (thale cress)	ATG8D	NP_178631.1
Pan troglodytes (chimpanzee)	GABARAPL1	XP_001146214.1
Rattus norvegicus (Norway rat)	Gabarapl1	NP_001037759.1
Gallus gallus (chicken)	GABARAPL1	XP_001231888.1
Danio rerio (zebrafish)	LOC793200	XP_003199067.2
Magnaporthe oryzae (rice blast fungus)	MGG_01062	XP_003717877.1
Xenopus tropicalis (tropical clawed frog)	gabarapl1	NP_001025652.1

Gene Ontology
Bibliography

Related articles in PubMed

Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.
Boeske A, Schwarten M, Ma P, Tusche M, M?tter J, M?ller C, Neudecker P, Hoffmann S, Willbold D
Scientific reports7(1)5979(2017 Jul)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1.
Mo J, Zhang D, Yang R
Bioscience reports36(5)(2016 Oct)

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.
Hervouet E, Claude-Taupin A, Gauthier T, Perez V, Fraichard A, Adami P, Despouy G, Monnien F, Algros MP, Jouvenot M, Delage-Mourroux R, Boyer-Guittaut M
BMC cancer15729(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results indicate that miR-195 regulates cell proliferation, migration, angiogenesis and autophagy of hEPCs by targeting GABARAPL1
Title: MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1.

Androgen deprivation downregulates Gabarapl1 in an AR dependent manner, resulting in the increase of autophagy flux
Title: Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.

Our data demonstrated that a specific decrease of GABARAPL1 expression in breast cancers was associated with both DNA methylation and histone deacetylation and that CREB-1 recruitment on GABARAPL1
Title: The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.

GABARAPL1 plays an important role in cell proliferation, invasion, and autophagic flux, as well as in mitochondrial homeostasis and cellular metabolic programs in a breast cancer cell line.
Title: The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells.

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.
Title: Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.

The following GABARAPL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GABARAPL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30044	NM_031412.4 Latest version!	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu46086	NM_001363598.2 Latest version!	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu46086	XM_005253344.4 Latest version!	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu46086	NM_001363598.1	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu30044	NM_031412.2	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GABARAPL1 ( NM_031412.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_113600.1 Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30044
Clone ID Related Accession (Same CDS sequence)	NM_031412.4 , NM_031412.2
Accession Version	NM_031412.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 354bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	gamma-aminobutyric acid receptor-associated protein-like 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115676.1 and BC028315.1. On Nov 22, 2018 this sequence version replaced NM_031412.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF087847.1, SRR3476690.521070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000266458.10/ ENSP00000266458.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGA CAATCATGAG 
GAAGACTATT TTCTGTATGT GGCCTACAGT GATGAGAGTG TCTATGGGAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113600.1
CDS	254..607
Translation	MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK

Target ORF information:

RefSeq Version	NM_031412.4
Organism	Homo sapiens(human)
Definition	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031412.4

ORF Insert Sequence:

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGA CAATCATGAG 
GAAGACTATT TTCTGTATGT GGCCTACAGT GATGAGAGTG TCTATGGGAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GABARAPL1 ( NM_031412.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_113600.1 Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), mRNA.

Price & Availability↑

CloneID	OHu30044
Clone ID Related Accession (Same CDS sequence)	NM_031412.4 , NM_031412.2
Accession Version	NM_031412.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 354bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	gamma-aminobutyric acid receptor-associated protein-like 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC028315.1. On Dec 16, 2004 this sequence version replaced NM_031412.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC028315.1, SRR1163658.451373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGA CAATCATGAG 
GAAGACTATT TTCTGTATGT GGCCTACAGT GATGAGAGTG TCTATGGGAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113600.1
CDS	241..594
Translation	MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK

Target ORF information:

RefSeq Version	NM_031412.2
Organism	Homo sapiens(human)
Definition	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031412.2

ORF Insert Sequence:

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGA CAATCATGAG 
GAAGACTATT TTCTGTATGT GGCCTACAGT GATGAGAGTG TCTATGGGAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GABARAPL1 ( NM_001363598.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350527.1 Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu46086
Clone ID Related Accession (Same CDS sequence)	NM_001363598.1 , XM_005253344.4 , NM_001363598.2
Accession Version	NM_001363598.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	gamma-aminobutyric acid receptor-associated protein-like 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115676.1 and DC365706.1. On May 24, 2018 this sequence version replaced XM_005253344.5. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL702909.1, SRR1660803.4448.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGT AATGGTTCTG 
GTTGCACAAT ACTGGATGCC GTCCAGTGCA GTCTGGCATC CTCTAGCCCT TGTTCTAGAT 
GCGTTGATAA CACATCTGAG AAGTGGGGCA GAAGGTGTTA TTTATCCGGA TCCTCTTACA 
TATGGCAGTG TAAGGCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350527.1
CDS	295..735
Translation	MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEVMVLVAQYWMPSSAVWHPLALVLDALITHLRSGAEGVIYPDPLTYGSVRL

Target ORF information:

RefSeq Version	NM_001363598.1
Organism	Homo sapiens(human)
Definition	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363598.1

ORF Insert Sequence:

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGT AATGGTTCTG 
GTTGCACAAT ACTGGATGCC GTCCAGTGCA GTCTGGCATC CTCTAGCCCT TGTTCTAGAT 
GCGTTGATAA CACATCTGAG AAGTGGGGCA GAAGGTGTTA TTTATCCGGA TCCTCTTACA 
TATGGCAGTG TAAGGCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GABARAPL1 ( NM_001363598.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350527.1 Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu46086
Clone ID Related Accession (Same CDS sequence)	NM_001363598.1 , XM_005253344.4 , NM_001363598.2
Accession Version	NM_001363598.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	gamma-aminobutyric acid receptor-associated protein-like 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC365706.1 and AC115676.1. On May 31, 2019 this sequence version replaced NM_001363598.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DC410338.1, DC332074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGT AATGGTTCTG 
GTTGCACAAT ACTGGATGCC GTCCAGTGCA GTCTGGCATC CTCTAGCCCT TGTTCTAGAT 
GCGTTGATAA CACATCTGAG AAGTGGGGCA GAAGGTGTTA TTTATCCGGA TCCTCTTACA 
TATGGCAGTG TAAGGCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350527.1
CDS	254..694
Translation	MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEVMVLVAQYWMPSSAVWHPLALVLDALITHLRSGAEGVIYPDPLTYGSVRL

Target ORF information:

RefSeq Version	NM_001363598.2
Organism	Homo sapiens(human)
Definition	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363598.2

ORF Insert Sequence:

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGT AATGGTTCTG 
GTTGCACAAT ACTGGATGCC GTCCAGTGCA GTCTGGCATC CTCTAGCCCT TGTTCTAGAT 
GCGTTGATAA CACATCTGAG AAGTGGGGCA GAAGGTGTTA TTTATCCGGA TCCTCTTACA 
TATGGCAGTG TAAGGCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GABARAPL1 ( XM_005253344.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005253401.1 Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46086
Clone ID Related Accession (Same CDS sequence)	NM_001363598.1 , XM_005253344.4 , NM_001363598.2
Accession Version	XM_005253344.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	gamma-aminobutyric acid receptor-associated protein-like 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005253344.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGT AATGGTTCTG 
GTTGCACAAT ACTGGATGCC GTCCAGTGCA GTCTGGCATC CTCTAGCCCT TGTTCTAGAT 
GCGTTGATAA CACATCTGAG AAGTGGGGCA GAAGGTGTTA TTTATCCGGA TCCTCTTACA 
TATGGCAGTG TAAGGCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005253401.1
CDS	290..730
Translation	MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEVMVLVAQYWMPSSAVWHPLALVLDALITHLRSGAEGVIYPDPLTYGSVRL

Target ORF information:

RefSeq Version	XM_005253344.4
Organism	Homo sapiens(human)
Definition	Homo sapiens GABA type A receptor associated protein like 1 (GABARAPL1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005253344.4

ORF Insert Sequence:

ATGAAGTTCC AGTACAAGGA GGACCATCCC TTTGAGTATC GGAAAAAGGA AGGAGAAAAG 
ATCCGGAAGA AATATCCGGA CAGGGTCCCC GTGATTGTAG AGAAGGCTCC AAAAGCCAGG 
GTGCCTGATC TGGACAAGAG GAAGTACCTA GTGCCCTCTG ACCTTACTGT TGGCCAGTTC 
TACTTCTTAA TCCGGAAGAG AATCCACCTG AGACCTGAGG ACGCCTTATT CTTCTTTGTC 
AACAACACCA TCCCTCCCAC CAGTGCTACC ATGGGCCAAC TGTATGAGGT AATGGTTCTG 
GTTGCACAAT ACTGGATGCC GTCCAGTGCA GTCTGGCATC CTCTAGCCCT TGTTCTAGAT 
GCGTTGATAA CACATCTGAG AAGTGGGGCA GAAGGTGTTA TTTATCCGGA TCCTCTTACA 
TATGGCAGTG TAAGGCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.
Scientific reports7(1)5979(2017 Jul)
Boeske A,Schwarten M,Ma P,Tusche M,M?tter J,M?ller C,Neudecker P,Hoffmann S,Willbold D

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1.
Bioscience reports36(5)(2016 Oct)
Mo J,Zhang D,Yang R

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.
BMC cancer15729(2015 Oct)
Hervouet E,Claude-Taupin A,Gauthier T,Perez V,Fraichard A,Adami P,Despouy G,Monnien F,Algros MP,Jouvenot M,Delage-Mourroux R,Boyer-Guittaut M

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GABARAPL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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