SPO11 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_005260379.3	XP_005260436.1	meiotic recombination protein SPO11 isoform X1
XM_005260381.3	XP_005260438.1	meiotic recombination protein SPO11 isoform X3
XM_005260382.4	XP_005260439.1	meiotic recombination protein SPO11 isoform X6
NM_198265.1	NP_937998.1	meiotic recombination protein SPO11 isoform b
NM_012444.2	NP_036576.1	meiotic recombination protein SPO11 isoform a
XM_011528756.2	XP_011527058.1	meiotic recombination protein SPO11 isoform X4
NM_012444.3	NP_036576.1	meiotic recombination protein SPO11 isoform a
NM_198265.2	NP_937998.1	meiotic recombination protein SPO11 isoform b
XM_005260380.3	XP_005260437.1	meiotic recombination protein SPO11 isoform X2
XM_011528757.2	XP_011527059.1	meiotic recombination protein SPO11 isoform X5

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30280	NM_198265.2 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu30195	NM_012444.3 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52976	XM_005260379.3 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52977	XM_005260380.3 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52978	XM_005260381.3 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52979	XM_005260382.4 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu66367	XM_011528756.2 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu66368	XM_011528757.2 Latest version!	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu30195	NM_012444.2	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu30280	NM_198265.1	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

SPO11 ( NM_198265.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_937998.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30280
Clone ID Related Accession (Same CDS sequence)	NM_198265.1 , NM_198265.2
Accession Version	NM_198265.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-24
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF169385.1 and BC033591.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) lacks an internal segment compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC033591.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GGTTTGAAGA TTCTGTGGGT CTTCAGATGG TATCCCATTG CACCACCAGA 
AAGATCAAAA GTGATTCACC AAAATCAGCT CAAAAATTTT CTCTAATCCT TAAAATATTG 
TCCATGATTT ATAAATTAGT ACAGAGCAAC ACTTATGCAA CCAAAAGGGA CATATATTAC 
ACTGACAGTC AACTCTTTGG TAACCAGACT GTCGTCGACA ATATTATCAA TGACATTTCT 
TGCATGTTAA AAGTGTCAAG GAGGAGTCTA CATATATTAT CTACATCAAA AGGTTTAATT 
GCTGGCAACT TAAGATACAT CGAGGAAGAT GGCACCAAAG TGAATTGTAC CTGTGGTGCA 
ACGGCTGTTG CTGTGCCATC GAATATTCAA GGAATTCGGA ATTTAGTTAC AGATGCAAAG 
TTTGTATTAA TTGTAGAAAA AGATGCAACA TTTCAGCGGC TCCTAGATGA CAACTTTTGC 
AACAAATTGT CTCCTTGCAT CATGATTACG GGAAAGGGAG TTCCTGATCT AAACACAAGA 
CTTTTAGTCA AGAAACTGTG GGATACATTT CATGTTCCTG TTTTCACTCT TGTAGATGCT 
GATCCACATG GCATAGAAAT AATGTGCATC TATAAGTATG GATCTATGTC TATGTCTTTT 
GAAGCTCATC ATCTCACAGT TCCAGCTATT AGATGGCTTG GTCTTCTCCC TTCTGATCTT 
AAAAGATTAA ATGTACCTAA AGATAGTTTG ATTCCACTGA CAAAAAGGGA CCAAATGAAA 
CTTGACAGTA TCCTGAGGAG ACCTTATGTT ACCTGCCAAC CATTTTGGAG AAAAGAAATG 
GAAATAATGG CAGACTCTAA AATGAAGGCA GAAATTCAAG CTTTGACTTT CCTATCATCA 
GATTATCTTT CCAGAGTGTA CTTACCTAAC AAATTAAAAT TTGGAGGATG GATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937998.1
CDS	94..1170
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASRFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	NM_198265.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198265.1

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GGTTTGAAGA TTCTGTGGGT CTTCAGATGG TATCCCATTG CACCACCAGA 
AAGATCAAAA GTGATTCACC AAAATCAGCT CAAAAATTTT CTCTAATCCT TAAAATATTG 
TCCATGATTT ATAAATTAGT ACAGAGCAAC ACTTATGCAA CCAAAAGGGA CATATATTAC 
ACTGACAGTC AACTCTTTGG TAACCAGACT GTCGTCGACA ATATTATCAA TGACATTTCT 
TGCATGTTAA AAGTGTCAAG GAGGAGTCTA CATATATTAT CTACATCAAA AGGTTTAATT 
GCTGGCAACT TAAGATACAT CGAGGAAGAT GGCACCAAAG TGAATTGTAC CTGTGGTGCA 
ACGGCTGTTG CTGTGCCATC GAATATTCAA GGAATTCGGA ATTTAGTTAC AGATGCAAAG 
TTTGTATTAA TTGTAGAAAA AGATGCAACA TTTCAGCGGC TCCTAGATGA CAACTTTTGC 
AACAAATTGT CTCCTTGCAT CATGATTACG GGAAAGGGAG TTCCTGATCT AAACACAAGA 
CTTTTAGTCA AGAAACTGTG GGATACATTT CATGTTCCTG TTTTCACTCT TGTAGATGCT 
GATCCACATG GCATAGAAAT AATGTGCATC TATAAGTATG GATCTATGTC TATGTCTTTT 
GAAGCTCATC ATCTCACAGT TCCAGCTATT AGATGGCTTG GTCTTCTCCC TTCTGATCTT 
AAAAGATTAA ATGTACCTAA AGATAGTTTG ATTCCACTGA CAAAAAGGGA CCAAATGAAA 
CTTGACAGTA TCCTGAGGAG ACCTTATGTT ACCTGCCAAC CATTTTGGAG AAAAGAAATG 
GAAATAATGG CAGACTCTAA AATGAAGGCA GAAATTCAAG CTTTGACTTT CCTATCATCA 
GATTATCTTT CCAGAGTGTA CTTACCTAAC AAATTAAAAT TTGGAGGATG GATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( NM_198265.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_937998.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30280
Clone ID Related Accession (Same CDS sequence)	NM_198265.1 , NM_198265.2
Accession Version	NM_198265.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF169385.1 and BC033591.1. On May 31, 2019 this sequence version replaced NM_198265.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) lacks an internal segment compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC033591.1, SRR5189667.230131.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GGTTTGAAGA TTCTGTGGGT CTTCAGATGG TATCCCATTG CACCACCAGA 
AAGATCAAAA GTGATTCACC AAAATCAGCT CAAAAATTTT CTCTAATCCT TAAAATATTG 
TCCATGATTT ATAAATTAGT ACAGAGCAAC ACTTATGCAA CCAAAAGGGA CATATATTAC 
ACTGACAGTC AACTCTTTGG TAACCAGACT GTCGTCGACA ATATTATCAA TGACATTTCT 
TGCATGTTAA AAGTGTCAAG GAGGAGTCTA CATATATTAT CTACATCAAA AGGTTTAATT 
GCTGGCAACT TAAGATACAT CGAGGAAGAT GGCACCAAAG TGAATTGTAC CTGTGGTGCA 
ACGGCTGTTG CTGTGCCATC GAATATTCAA GGAATTCGGA ATTTAGTTAC AGATGCAAAG 
TTTGTATTAA TTGTAGAAAA AGATGCAACA TTTCAGCGGC TCCTAGATGA CAACTTTTGC 
AACAAATTGT CTCCTTGCAT CATGATTACG GGAAAGGGAG TTCCTGATCT AAACACAAGA 
CTTTTAGTCA AGAAACTGTG GGATACATTT CATGTTCCTG TTTTCACTCT TGTAGATGCT 
GATCCACATG GCATAGAAAT AATGTGCATC TATAAGTATG GATCTATGTC TATGTCTTTT 
GAAGCTCATC ATCTCACAGT TCCAGCTATT AGATGGCTTG GTCTTCTCCC TTCTGATCTT 
AAAAGATTAA ATGTACCTAA AGATAGTTTG ATTCCACTGA CAAAAAGGGA CCAAATGAAA 
CTTGACAGTA TCCTGAGGAG ACCTTATGTT ACCTGCCAAC CATTTTGGAG AAAAGAAATG 
GAAATAATGG CAGACTCTAA AATGAAGGCA GAAATTCAAG CTTTGACTTT CCTATCATCA 
GATTATCTTT CCAGAGTGTA CTTACCTAAC AAATTAAAAT TTGGAGGATG GATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937998.1
CDS	66..1142
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASRFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	NM_198265.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198265.2

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GGTTTGAAGA TTCTGTGGGT CTTCAGATGG TATCCCATTG CACCACCAGA 
AAGATCAAAA GTGATTCACC AAAATCAGCT CAAAAATTTT CTCTAATCCT TAAAATATTG 
TCCATGATTT ATAAATTAGT ACAGAGCAAC ACTTATGCAA CCAAAAGGGA CATATATTAC 
ACTGACAGTC AACTCTTTGG TAACCAGACT GTCGTCGACA ATATTATCAA TGACATTTCT 
TGCATGTTAA AAGTGTCAAG GAGGAGTCTA CATATATTAT CTACATCAAA AGGTTTAATT 
GCTGGCAACT TAAGATACAT CGAGGAAGAT GGCACCAAAG TGAATTGTAC CTGTGGTGCA 
ACGGCTGTTG CTGTGCCATC GAATATTCAA GGAATTCGGA ATTTAGTTAC AGATGCAAAG 
TTTGTATTAA TTGTAGAAAA AGATGCAACA TTTCAGCGGC TCCTAGATGA CAACTTTTGC 
AACAAATTGT CTCCTTGCAT CATGATTACG GGAAAGGGAG TTCCTGATCT AAACACAAGA 
CTTTTAGTCA AGAAACTGTG GGATACATTT CATGTTCCTG TTTTCACTCT TGTAGATGCT 
GATCCACATG GCATAGAAAT AATGTGCATC TATAAGTATG GATCTATGTC TATGTCTTTT 
GAAGCTCATC ATCTCACAGT TCCAGCTATT AGATGGCTTG GTCTTCTCCC TTCTGATCTT 
AAAAGATTAA ATGTACCTAA AGATAGTTTG ATTCCACTGA CAAAAAGGGA CCAAATGAAA 
CTTGACAGTA TCCTGAGGAG ACCTTATGTT ACCTGCCAAC CATTTTGGAG AAAAGAAATG 
GAAATAATGG CAGACTCTAA AATGAAGGCA GAAATTCAAG CTTTGACTTT CCTATCATCA 
GATTATCTTT CCAGAGTGTA CTTACCTAAC AAATTAAAAT TTGGAGGATG GATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( NM_012444.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_036576.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30195
Clone ID Related Accession (Same CDS sequence)	NM_012444.2 , NM_012444.3
Accession Version	NM_012444.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-24
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF169385.1, AF149310.1 and BC033591.1. On Nov 7, 2003 this sequence version replaced NM_012444.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF169385.1, AF149310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGGGAAAG GGAGTTCCTG ATCTAAACAC AAGACTTTTA 
GTCAAGAAAC TGTGGGATAC ATTTCATGTT CCTGTTTTCA CTCTTGTAGA TGCTGATCCA 
CATGGCATAG AAATAATGTG CATCTATAAG TATGGATCTA TGTCTATGTC TTTTGAAGCT 
CATCATCTCA CAGTTCCAGC TATTAGATGG CTTGGTCTTC TCCCTTCTGA TCTTAAAAGA 
TTAAATGTAC CTAAAGATAG TTTGATTCCA CTGACAAAAA GGGACCAAAT GAAACTTGAC 
AGTATCCTGA GGAGACCTTA TGTTACCTGC CAACCATTTT GGAGAAAAGA AATGGAAATA 
ATGGCAGACT CTAAAATGAA GGCAGAAATT CAAGCTTTGA CTTTCCTATC ATCAGATTAT 
CTTTCCAGAG TGTACTTACC TAACAAATTA AAATTTGGAG GATGGATATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036576.1
CDS	94..1284
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	NM_012444.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012444.2

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGGGAAAG GGAGTTCCTG ATCTAAACAC AAGACTTTTA 
GTCAAGAAAC TGTGGGATAC ATTTCATGTT CCTGTTTTCA CTCTTGTAGA TGCTGATCCA 
CATGGCATAG AAATAATGTG CATCTATAAG TATGGATCTA TGTCTATGTC TTTTGAAGCT 
CATCATCTCA CAGTTCCAGC TATTAGATGG CTTGGTCTTC TCCCTTCTGA TCTTAAAAGA 
TTAAATGTAC CTAAAGATAG TTTGATTCCA CTGACAAAAA GGGACCAAAT GAAACTTGAC 
AGTATCCTGA GGAGACCTTA TGTTACCTGC CAACCATTTT GGAGAAAAGA AATGGAAATA 
ATGGCAGACT CTAAAATGAA GGCAGAAATT CAAGCTTTGA CTTTCCTATC ATCAGATTAT 
CTTTCCAGAG TGTACTTACC TAACAAATTA AAATTTGGAG GATGGATATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( NM_012444.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036576.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30195
Clone ID Related Accession (Same CDS sequence)	NM_012444.2 , NM_012444.3
Accession Version	NM_012444.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF169385.1, AF149310.1 and BC033591.1. On May 17, 2019 this sequence version replaced NM_012444.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF149310.1, AF169385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371263.8/ ENSP00000360310.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGGGAAAG GGAGTTCCTG ATCTAAACAC AAGACTTTTA 
GTCAAGAAAC TGTGGGATAC ATTTCATGTT CCTGTTTTCA CTCTTGTAGA TGCTGATCCA 
CATGGCATAG AAATAATGTG CATCTATAAG TATGGATCTA TGTCTATGTC TTTTGAAGCT 
CATCATCTCA CAGTTCCAGC TATTAGATGG CTTGGTCTTC TCCCTTCTGA TCTTAAAAGA 
TTAAATGTAC CTAAAGATAG TTTGATTCCA CTGACAAAAA GGGACCAAAT GAAACTTGAC 
AGTATCCTGA GGAGACCTTA TGTTACCTGC CAACCATTTT GGAGAAAAGA AATGGAAATA 
ATGGCAGACT CTAAAATGAA GGCAGAAATT CAAGCTTTGA CTTTCCTATC ATCAGATTAT 
CTTTCCAGAG TGTACTTACC TAACAAATTA AAATTTGGAG GATGGATATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036576.1
CDS	66..1256
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	NM_012444.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012444.3

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGGGAAAG GGAGTTCCTG ATCTAAACAC AAGACTTTTA 
GTCAAGAAAC TGTGGGATAC ATTTCATGTT CCTGTTTTCA CTCTTGTAGA TGCTGATCCA 
CATGGCATAG AAATAATGTG CATCTATAAG TATGGATCTA TGTCTATGTC TTTTGAAGCT 
CATCATCTCA CAGTTCCAGC TATTAGATGG CTTGGTCTTC TCCCTTCTGA TCTTAAAAGA 
TTAAATGTAC CTAAAGATAG TTTGATTCCA CTGACAAAAA GGGACCAAAT GAAACTTGAC 
AGTATCCTGA GGAGACCTTA TGTTACCTGC CAACCATTTT GGAGAAAAGA AATGGAAATA 
ATGGCAGACT CTAAAATGAA GGCAGAAATT CAAGCTTTGA CTTTCCTATC ATCAGATTAT 
CTTTCCAGAG TGTACTTACC TAACAAATTA AAATTTGGAG GATGGATATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( XM_005260379.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260436.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu52976
Clone ID Related Accession (Same CDS sequence)	XM_005260379.3
Accession Version	XM_005260379.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005260379.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGTCAACA CCAGTCTTTC AGCACCTGAA ATCCAAGGGA 
AAGGGAGTTC CTGATCTAAA CACAAGACTT TTAGTCAAGA AACTGTGGGA TACATTTCAT 
GTTCCTGTTT TCACTCTTGT AGATGCTGAT CCACATGGCA TAGAAATAAT GTGCATCTAT 
AAGTATGGAT CTATGTCTAT GTCTTTTGAA GCTCATCATC TCACAGTTCC AGCTATTAGA 
TGGCTTGGTC TTCTCCCTTC TGATCTTAAA AGATTAAATG TACCTAAAGA TAGTTTGATT 
CCACTGACAA AAAGGGACCA AATGAAACTT GACAGTATCC TGAGGAGACC TTATGTTACC 
TGCCAACCAT TTTGGAGAAA AGAAATGGAA ATAATGGCAG ACTCTAAAAT GAAGGCAGAA 
ATTCAAGCTT TGACTTTCCT ATCATCAGAT TATCTTTCCA GAGTGTACTT ACCTAACAAA 
TTAAAATTTG GAGGATGGAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260436.1
CDS	112..1335
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITSTPVFQHLKSKGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	XM_005260379.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260379.3

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGTCAACA CCAGTCTTTC AGCACCTGAA ATCCAAGGGA 
AAGGGAGTTC CTGATCTAAA CACAAGACTT TTAGTCAAGA AACTGTGGGA TACATTTCAT 
GTTCCTGTTT TCACTCTTGT AGATGCTGAT CCACATGGCA TAGAAATAAT GTGCATCTAT 
AAGTATGGAT CTATGTCTAT GTCTTTTGAA GCTCATCATC TCACAGTTCC AGCTATTAGA 
TGGCTTGGTC TTCTCCCTTC TGATCTTAAA AGATTAAATG TACCTAAAGA TAGTTTGATT 
CCACTGACAA AAAGGGACCA AATGAAACTT GACAGTATCC TGAGGAGACC TTATGTTACC 
TGCCAACCAT TTTGGAGAAA AGAAATGGAA ATAATGGCAG ACTCTAAAAT GAAGGCAGAA 
ATTCAAGCTT TGACTTTCCT ATCATCAGAT TATCTTTCCA GAGTGTACTT ACCTAACAAA 
TTAAAATTTG GAGGATGGAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( XM_005260380.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260437.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu52977
Clone ID Related Accession (Same CDS sequence)	XM_005260380.3
Accession Version	XM_005260380.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005260380.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGATTACAG ATGCAAAGTT TGTATTAATT 
GTAGAAAAAG ATGCAACATT TCAGCGGCTC CTAGATGACA ACTTTTGCAA CAAATTGTCT 
CCTTGCATCA TGATTACGTC AACACCAGTC TTTCAGCACC TGAAATCCAA GGGAAAGGGA 
GTTCCTGATC TAAACACAAG ACTTTTAGTC AAGAAACTGT GGGATACATT TCATGTTCCT 
GTTTTCACTC TTGTAGATGC TGATCCACAT GGCATAGAAA TAATGTGCAT CTATAAGTAT 
GGATCTATGT CTATGTCTTT TGAAGCTCAT CATCTCACAG TTCCAGCTAT TAGATGGCTT 
GGTCTTCTCC CTTCTGATCT TAAAAGATTA AATGTACCTA AAGATAGTTT GATTCCACTG 
ACAAAAAGGG ACCAAATGAA ACTTGACAGT ATCCTGAGGA GACCTTATGT TACCTGCCAA 
CCATTTTGGA GAAAAGAAAT GGAAATAATG GCAGACTCTA AAATGAAGGC AGAAATTCAA 
GCTTTGACTT TCCTATCATC AGATTATCTT TCCAGAGTGT ACTTACCTAA CAAATTAAAA 
TTTGGAGGAT GGATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260437.1
CDS	112..1329
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRITDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITSTPVFQHLKSKGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	XM_005260380.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260380.3

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGATTACAG ATGCAAAGTT TGTATTAATT 
GTAGAAAAAG ATGCAACATT TCAGCGGCTC CTAGATGACA ACTTTTGCAA CAAATTGTCT 
CCTTGCATCA TGATTACGTC AACACCAGTC TTTCAGCACC TGAAATCCAA GGGAAAGGGA 
GTTCCTGATC TAAACACAAG ACTTTTAGTC AAGAAACTGT GGGATACATT TCATGTTCCT 
GTTTTCACTC TTGTAGATGC TGATCCACAT GGCATAGAAA TAATGTGCAT CTATAAGTAT 
GGATCTATGT CTATGTCTTT TGAAGCTCAT CATCTCACAG TTCCAGCTAT TAGATGGCTT 
GGTCTTCTCC CTTCTGATCT TAAAAGATTA AATGTACCTA AAGATAGTTT GATTCCACTG 
ACAAAAAGGG ACCAAATGAA ACTTGACAGT ATCCTGAGGA GACCTTATGT TACCTGCCAA 
CCATTTTGGA GAAAAGAAAT GGAAATAATG GCAGACTCTA AAATGAAGGC AGAAATTCAA 
GCTTTGACTT TCCTATCATC AGATTATCTT TCCAGAGTGT ACTTACCTAA CAAATTAAAA 
TTTGGAGGAT GGATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( XM_005260381.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260438.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu52978
Clone ID Related Accession (Same CDS sequence)	XM_005260381.3
Accession Version	XM_005260381.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005260381.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGATTACAG ATGCAAAGTT TGTATTAATT 
GTAGAAAAAG ATGCAACATT TCAGCGGCTC CTAGATGACA ACTTTTGCAA CAAATTGTCT 
CCTTGCATCA TGATTACGGG AAAGGGAGTT CCTGATCTAA ACACAAGACT TTTAGTCAAG 
AAACTGTGGG ATACATTTCA TGTTCCTGTT TTCACTCTTG TAGATGCTGA TCCACATGGC 
ATAGAAATAA TGTGCATCTA TAAGTATGGA TCTATGTCTA TGTCTTTTGA AGCTCATCAT 
CTCACAGTTC CAGCTATTAG ATGGCTTGGT CTTCTCCCTT CTGATCTTAA AAGATTAAAT 
GTACCTAAAG ATAGTTTGAT TCCACTGACA AAAAGGGACC AAATGAAACT TGACAGTATC 
CTGAGGAGAC CTTATGTTAC CTGCCAACCA TTTTGGAGAA AAGAAATGGA AATAATGGCA 
GACTCTAAAA TGAAGGCAGA AATTCAAGCT TTGACTTTCC TATCATCAGA TTATCTTTCC 
AGAGTGTACT TACCTAACAA ATTAAAATTT GGAGGATGGA TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260438.1
CDS	112..1296
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRITDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	XM_005260381.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260381.3

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGATTACAG ATGCAAAGTT TGTATTAATT 
GTAGAAAAAG ATGCAACATT TCAGCGGCTC CTAGATGACA ACTTTTGCAA CAAATTGTCT 
CCTTGCATCA TGATTACGGG AAAGGGAGTT CCTGATCTAA ACACAAGACT TTTAGTCAAG 
AAACTGTGGG ATACATTTCA TGTTCCTGTT TTCACTCTTG TAGATGCTGA TCCACATGGC 
ATAGAAATAA TGTGCATCTA TAAGTATGGA TCTATGTCTA TGTCTTTTGA AGCTCATCAT 
CTCACAGTTC CAGCTATTAG ATGGCTTGGT CTTCTCCCTT CTGATCTTAA AAGATTAAAT 
GTACCTAAAG ATAGTTTGAT TCCACTGACA AAAAGGGACC AAATGAAACT TGACAGTATC 
CTGAGGAGAC CTTATGTTAC CTGCCAACCA TTTTGGAGAA AAGAAATGGA AATAATGGCA 
GACTCTAAAA TGAAGGCAGA AATTCAAGCT TTGACTTTCC TATCATCAGA TTATCTTTCC 
AGAGTGTACT TACCTAACAA ATTAAAATTT GGAGGATGGA TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( XM_005260382.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260439.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu52979
Clone ID Related Accession (Same CDS sequence)	XM_005260382.4
Accession Version	XM_005260382.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005260382.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGTCAACA CCAGTCTTTC AGCACCTGAA ATCCAAGGGA 
AAGGGAGTTC CTGATCTAAA CACAAGACTT TTAGTCAAGA AACTGTGGGA TACATTTCAT 
GTTCCTGTTT TCACTCTTGT AGATGCTGAT CCACATGGCA TAGAAATAAT GTGCATCTAT 
AAGTATGGAT CTATGATTAA ATGTACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260439.1
CDS	112..1041
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASSSEVLASIENIIQDIITSLARNEAPAFTIDNRSSWENIKFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITSTPVFQHLKSKGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMIKCT

Target ORF information:

RefSeq Version	XM_005260382.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260382.4

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GTTCTGAGGT TCTTGCATCT ATAGAAAATA TTATCCAAGA CATAATCACA 
AGCTTGGCAA GAAATGAAGC ACCTGCATTC ACGATAGACA ACAGATCAAG CTGGGAAAAC 
ATAAAGTTTG AAGATTCTGT GGGTCTTCAG ATGGTATCCC ATTGCACCAC CAGAAAGATC 
AAAAGTGATT CACCAAAATC AGCTCAAAAA TTTTCTCTAA TCCTTAAAAT ATTGTCCATG 
ATTTATAAAT TAGTACAGAG CAACACTTAT GCAACCAAAA GGGACATATA TTACACTGAC 
AGTCAACTCT TTGGTAACCA GACTGTCGTC GACAATATTA TCAATGACAT TTCTTGCATG 
TTAAAAGTGT CAAGGAGGAG TCTACATATA TTATCTACAT CAAAAGGTTT AATTGCTGGC 
AACTTAAGAT ACATCGAGGA AGATGGCACC AAAGTGAATT GTACCTGTGG TGCAACGGCT 
GTTGCTGTGC CATCGAATAT TCAAGGAATT CGGAATTTAG TTACAGATGC AAAGTTTGTA 
TTAATTGTAG AAAAAGATGC AACATTTCAG CGGCTCCTAG ATGACAACTT TTGCAACAAA 
TTGTCTCCTT GCATCATGAT TACGTCAACA CCAGTCTTTC AGCACCTGAA ATCCAAGGGA 
AAGGGAGTTC CTGATCTAAA CACAAGACTT TTAGTCAAGA AACTGTGGGA TACATTTCAT 
GTTCCTGTTT TCACTCTTGT AGATGCTGAT CCACATGGCA TAGAAATAAT GTGCATCTAT 
AAGTATGGAT CTATGATTAA ATGTACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( XM_011528756.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527058.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu66367
Clone ID Related Accession (Same CDS sequence)	XM_011528756.2
Accession Version	XM_011528756.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011528756.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GGTTTGAAGA TTCTGTGGGT CTTCAGATGG TATCCCATTG CACCACCAGA 
AAGATCAAAA GTGATTCACC AAAATCAGCT CAAAAATTTT CTCTAATCCT TAAAATATTG 
TCCATGATTT ATAAATTAGT ACAGAGCAAC ACTTATGCAA CCAAAAGGGA CATATATTAC 
ACTGACAGTC AACTCTTTGG TAACCAGACT GTCGTCGACA ATATTATCAA TGACATTTCT 
TGCATGTTAA AAGTGTCAAG GAGGAGTCTA CATATATTAT CTACATCAAA AGGTTTAATT 
GCTGGCAACT TAAGATACAT CGAGGAAGAT GGCACCAAAG TGAATTGTAC CTGTGGTGCA 
ACGGCTGTTG CTGTGCCATC GAATATTCAA GGAATTCGGA ATTTAGTTAC AGATGCAAAG 
TTTGTATTAA TTGTAGAAAA AGATGCAACA TTTCAGCGGC TCCTAGATGA CAACTTTTGC 
AACAAATTGT CTCCTTGCAT CATGATTACG TCAACACCAG TCTTTCAGCA CCTGAAATCC 
AAGGGAAAGG GAGTTCCTGA TCTAAACACA AGACTTTTAG TCAAGAAACT GTGGGATACA 
TTTCATGTTC CTGTTTTCAC TCTTGTAGAT GCTGATCCAC ATGGCATAGA AATAATGTGC 
ATCTATAAGT ATGGATCTAT GTCTATGTCT TTTGAAGCTC ATCATCTCAC AGTTCCAGCT 
ATTAGATGGC TTGGTCTTCT CCCTTCTGAT CTTAAAAGAT TAAATGTACC TAAAGATAGT 
TTGATTCCAC TGACAAAAAG GGACCAAATG AAACTTGACA GTATCCTGAG GAGACCTTAT 
GTTACCTGCC AACCATTTTG GAGAAAAGAA ATGGAAATAA TGGCAGACTC TAAAATGAAG 
GCAGAAATTC AAGCTTTGAC TTTCCTATCA TCAGATTATC TTTCCAGAGT GTACTTACCT 
AACAAATTAA AATTTGGAGG ATGGATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527058.1
CDS	112..1221
Translation	MAFAPMGPEASFFDVLDRHRESLLAALRRGGREPPTGGSRLASRFEDSVGLQMVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITSTPVFQHLKSKGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	XM_011528756.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528756.2

ORF Insert Sequence:

ATGGCCTTTG CACCTATGGG GCCCGAGGCC TCGTTCTTCG ACGTTTTGGA CCGACACAGG 
GAGTCCCTGC TGGCTGCCCT GAGGAGAGGT GGCAGGGAGC CCCCAACTGG GGGAAGCCGC 
CTGGCCTCCA GGTTTGAAGA TTCTGTGGGT CTTCAGATGG TATCCCATTG CACCACCAGA 
AAGATCAAAA GTGATTCACC AAAATCAGCT CAAAAATTTT CTCTAATCCT TAAAATATTG 
TCCATGATTT ATAAATTAGT ACAGAGCAAC ACTTATGCAA CCAAAAGGGA CATATATTAC 
ACTGACAGTC AACTCTTTGG TAACCAGACT GTCGTCGACA ATATTATCAA TGACATTTCT 
TGCATGTTAA AAGTGTCAAG GAGGAGTCTA CATATATTAT CTACATCAAA AGGTTTAATT 
GCTGGCAACT TAAGATACAT CGAGGAAGAT GGCACCAAAG TGAATTGTAC CTGTGGTGCA 
ACGGCTGTTG CTGTGCCATC GAATATTCAA GGAATTCGGA ATTTAGTTAC AGATGCAAAG 
TTTGTATTAA TTGTAGAAAA AGATGCAACA TTTCAGCGGC TCCTAGATGA CAACTTTTGC 
AACAAATTGT CTCCTTGCAT CATGATTACG TCAACACCAG TCTTTCAGCA CCTGAAATCC 
AAGGGAAAGG GAGTTCCTGA TCTAAACACA AGACTTTTAG TCAAGAAACT GTGGGATACA 
TTTCATGTTC CTGTTTTCAC TCTTGTAGAT GCTGATCCAC ATGGCATAGA AATAATGTGC 
ATCTATAAGT ATGGATCTAT GTCTATGTCT TTTGAAGCTC ATCATCTCAC AGTTCCAGCT 
ATTAGATGGC TTGGTCTTCT CCCTTCTGAT CTTAAAAGAT TAAATGTACC TAAAGATAGT 
TTGATTCCAC TGACAAAAAG GGACCAAATG AAACTTGACA GTATCCTGAG GAGACCTTAT 
GTTACCTGCC AACCATTTTG GAGAAAAGAA ATGGAAATAA TGGCAGACTC TAAAATGAAG 
GCAGAAATTC AAGCTTTGAC TTTCCTATCA TCAGATTATC TTTCCAGAGT GTACTTACCT 
AACAAATTAA AATTTGGAGG ATGGATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPO11 ( XM_011528757.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527059.1 Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu66368
Clone ID Related Accession (Same CDS sequence)	XM_011528757.2
Accession Version	XM_011528757.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	meiotic recombination protein SPO11 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011528757.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTATCCC ATTGCACCAC CAGAAAGATC AAAAGTGATT CACCAAAATC AGCTCAAAAA 
TTTTCTCTAA TCCTTAAAAT ATTGTCCATG ATTTATAAAT TAGTACAGAG CAACACTTAT 
GCAACCAAAA GGGACATATA TTACACTGAC AGTCAACTCT TTGGTAACCA GACTGTCGTC 
GACAATATTA TCAATGACAT TTCTTGCATG TTAAAAGTGT CAAGGAGGAG TCTACATATA 
TTATCTACAT CAAAAGGTTT AATTGCTGGC AACTTAAGAT ACATCGAGGA AGATGGCACC 
AAAGTGAATT GTACCTGTGG TGCAACGGCT GTTGCTGTGC CATCGAATAT TCAAGGAATT 
CGGAATTTAG TTACAGATGC AAAGTTTGTA TTAATTGTAG AAAAAGATGC AACATTTCAG 
CGGCTCCTAG ATGACAACTT TTGCAACAAA TTGTCTCCTT GCATCATGAT TACGTCAACA 
CCAGTCTTTC AGCACCTGAA ATCCAAGGGA AAGGGAGTTC CTGATCTAAA CACAAGACTT 
TTAGTCAAGA AACTGTGGGA TACATTTCAT GTTCCTGTTT TCACTCTTGT AGATGCTGAT 
CCACATGGCA TAGAAATAAT GTGCATCTAT AAGTATGGAT CTATGTCTAT GTCTTTTGAA 
GCTCATCATC TCACAGTTCC AGCTATTAGA TGGCTTGGTC TTCTCCCTTC TGATCTTAAA 
AGATTAAATG TACCTAAAGA TAGTTTGATT CCACTGACAA AAAGGGACCA AATGAAACTT 
GACAGTATCC TGAGGAGACC TTATGTTACC TGCCAACCAT TTTGGAGAAA AGAAATGGAA 
ATAATGGCAG ACTCTAAAAT GAAGGCAGAA ATTCAAGCTT TGACTTTCCT ATCATCAGAT 
TATCTTTCCA GAGTGTACTT ACCTAACAAA TTAAAATTTG GAGGATGGAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527059.1
CDS	216..1169
Translation	MVSHCTTRKIKSDSPKSAQKFSLILKILSMIYKLVQSNTYATKRDIYYTDSQLFGNQTVVDNIINDISCMLKVSRRSLHILSTSKGLIAGNLRYIEEDGTKVNCTCGATAVAVPSNIQGIRNLVTDAKFVLIVEKDATFQRLLDDNFCNKLSPCIMITSTPVFQHLKSKGKGVPDLNTRLLVKKLWDTFHVPVFTLVDADPHGIEIMCIYKYGSMSMSFEAHHLTVPAIRWLGLLPSDLKRLNVPKDSLIPLTKRDQMKLDSILRRPYVTCQPFWRKEMEIMADSKMKAEIQALTFLSSDYLSRVYLPNKLKFGGWI

Target ORF information:

RefSeq Version	XM_011528757.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SPO11 initiator of meiotic double stranded breaks (SPO11), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528757.2

ORF Insert Sequence:

ATGGTATCCC ATTGCACCAC CAGAAAGATC AAAAGTGATT CACCAAAATC AGCTCAAAAA 
TTTTCTCTAA TCCTTAAAAT ATTGTCCATG ATTTATAAAT TAGTACAGAG CAACACTTAT 
GCAACCAAAA GGGACATATA TTACACTGAC AGTCAACTCT TTGGTAACCA GACTGTCGTC 
GACAATATTA TCAATGACAT TTCTTGCATG TTAAAAGTGT CAAGGAGGAG TCTACATATA 
TTATCTACAT CAAAAGGTTT AATTGCTGGC AACTTAAGAT ACATCGAGGA AGATGGCACC 
AAAGTGAATT GTACCTGTGG TGCAACGGCT GTTGCTGTGC CATCGAATAT TCAAGGAATT 
CGGAATTTAG TTACAGATGC AAAGTTTGTA TTAATTGTAG AAAAAGATGC AACATTTCAG 
CGGCTCCTAG ATGACAACTT TTGCAACAAA TTGTCTCCTT GCATCATGAT TACGTCAACA 
CCAGTCTTTC AGCACCTGAA ATCCAAGGGA AAGGGAGTTC CTGATCTAAA CACAAGACTT 
TTAGTCAAGA AACTGTGGGA TACATTTCAT GTTCCTGTTT TCACTCTTGT AGATGCTGAT 
CCACATGGCA TAGAAATAAT GTGCATCTAT AAGTATGGAT CTATGTCTAT GTCTTTTGAA 
GCTCATCATC TCACAGTTCC AGCTATTAGA TGGCTTGGTC TTCTCCCTTC TGATCTTAAA 
AGATTAAATG TACCTAAAGA TAGTTTGATT CCACTGACAA AAAGGGACCA AATGAAACTT 
GACAGTATCC TGAGGAGACC TTATGTTACC TGCCAACCAT TTTGGAGAAA AGAAATGGAA 
ATAATGGCAG ACTCTAAAAT GAAGGCAGAA ATTCAAGCTT TGACTTTCCT ATCATCAGAT 
TATCTTTCCA GAGTGTACTT ACCTAACAAA TTAAAATTTG GAGGATGGAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	SPO11
Entrez Gene ID	23626
Full Name	SPO11, initiator of meiotic double stranded breaks
Synonyms	CT35,SPATA43,TOPVIA
General protein information	Preferred Names SPO11, initiator of meiotic double stranded breaks Names meiotic recombination protein SPO11 SPO11 meiotic protein covalently bound to DSB homolog cancer/testis antigen 35 spermatogenesis associated 43
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.31
Summary	Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008].
Disorder MIM:	605114

Pan troglodytes (chimpanzee)	SPO11	XP_514741.2
Bos taurus (cattle)	SPO11	NP_001180019.1
Rattus norvegicus (Norway rat)	Spo11	NP_001102434.1
Gallus gallus (chicken)	SPO11	XP_001232076.2
Drosophila melanogaster (fruit fly)	mei-W68	NP_995901.1
Arabidopsis thaliana (thale cress)	RHL2	NP_195902.1
Oryza sativa (rice)	Os03g0284800	NP_001049765.2
Canis lupus familiaris (dog)	SPO11	XP_853487.1
Mus musculus (house mouse)	Spo11	NP_036176.1
Danio rerio (zebrafish)	spo11	NP_991245.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010898	XP_309793.4
Homo sapiens (human)	SPO11	NP_036576.1
	SPO11	XP_001088572.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

SPO11 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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