CBLC cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CBLC
Entrez Gene ID	23624
Full Name	Cbl proto-oncogene C
Synonyms	CBL-3,CBL-SL,RNF57
General protein information	Preferred Names Cbl proto-oncogene C Names E3 ubiquitin-protein ligase CBL-C Cas-Br-M (murine) ecotropic retroviral transforming sequence c Cas-Br-M (murine) ectropic retroviral transforming sequence c Cbl proto-oncogene C, E3 ubiquitin protein ligase Cbl proto-oncogene, E3 ubiquitin protein ligase C RING finger protein 57 RING-type E3 ubiquitin transferase CBL-C SH3-binding protein CBL-3 SH3-binding protein CBL-C signal transduction protein CBL-C
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.32
Summary	This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].
Disorder MIM:	608453

mRNA and Protein(s)

mRNA	Protein	Name
XM_011526688.2	XP_011524990.1	E3 ubiquitin-protein ligase CBL-C isoform X1
NM_012116.4	NP_036248.3	E3 ubiquitin-protein ligase CBL-C isoform 1
NM_001130852.1	NP_001124324.1	E3 ubiquitin-protein ligase CBL-C isoform 2
XM_011526690.2	XP_011524992.1	E3 ubiquitin-protein ligase CBL-C isoform X4
NM_012116.3	NP_036248.3	E3 ubiquitin-protein ligase CBL-C isoform 1
XM_011526689.2	XP_011524991.1	E3 ubiquitin-protein ligase CBL-C isoform X2
XM_005258696.3	XP_005258753.1	E3 ubiquitin-protein ligase CBL-C isoform X3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CBLC	XP_005616520.1
Mus musculus (house mouse)	Cblc	NP_075713.3
Homo sapiens (human)	CBLC	NP_036248.3
Rattus norvegicus (Norway rat)	Cblc	NP_001030092.1
Pan troglodytes (chimpanzee)	CBLC	XP_003954528.1
	CBLC	XP_001109370.1
Bos taurus (cattle)	CBLC	NP_001094718.1

Gene Ontology
Bibliography

Related articles in PubMed

Optical coherence tomography morphology and evolution in cblC disease-related maculopathy in a case series of very young patients.
Bacci GM, Donati MA, Pasquini E, Munier F, Cavicchi C, Morrone A, Sodi A, Murro V, Garcia Segarra N, Defilippi C, Bussolin L, Caputo R
Acta ophthalmologica95(8)e776-e782(2017 Dec)

Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.
Gherasim C, Ruetz M, Li Z, Hudolin S, Banerjee R
The Journal of biological chemistry290(18)11393-402(2015 May)

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity.
Frankum J, Moudry P, Brough R, Hodny Z, Ashworth A, Bartek J, Lord CJ
Oncotarget6(13)10746-58(2015 May)

The Ubiquitin Ligase CBLC Maintains the Network Organization of the Golgi Apparatus.
Lee WY, Goh G, Chia J, Boey A, Gunko NV, Bard F
PloS one10(9)e0138789(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Methylmalonic aciduria with homocystinuria cblC is a multisystemic metabolic disease affecting cobalamin metabolism. The presence of retinal alterations in cblC is a common feature and it is reported to develop more frequently and into a more severe form in the early-onset phenotype, suggesting to some extent a correlation with the biochemical phenotype
Title: Optical coherence tomography morphology and evolution in cblC disease-related maculopathy in a case series of very young patients.

the effects of two pathogenic missense mutations on the the catalytic activities of the human B12-processing chaperone CblC
Title: Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.

Silencing of CBLC causes increased sensitivity to PARP1 inhibitor olaparib in breast cancer cell line models and that defective homologous recombination (HR) DNA repair is the likely cause.
Title: Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity.

Data suggest that ubiquitin ligase CBLC controls mostly network organization of the Golgi Apparatus.
Title: The Ubiquitin Ligase CBLC Maintains the Network Organization of the Golgi Apparatus.

This retrospective multicentre study evaluates clinical, biochemical and genetic findings in 88 cblC patients
Title: Clinical presentation and outcome in a series of 88 patients with the cblC defect.

The following CBLC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CBLC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06057	NM_012116.4 Latest version!	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu07090	NM_001130852.1 Latest version!	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$251.30 $359.00
OHu52144	XM_005258696.3 Latest version!	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu66364	XM_011526688.2 Latest version!	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu66365	XM_011526689.2 Latest version!	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu66366	XM_011526690.2 Latest version!	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu06057	NM_012116.3	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CBLC ( NM_012116.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036248.3 Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06057
Clone ID Related Accession (Same CDS sequence)	NM_012116.4 , NM_012116.3
Accession Version	NM_012116.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL-C isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF117646.1, BC028915.1 and AC092066.4. This sequence is a reference standard in the RefSeqGene project. On May 10, 2018 this sequence version replaced NM_012116.3. Transcript Variant: This variant (1) represents the longer transcript and encodes protein isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279844.3243.1, AF117646.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000647358.2/ ENSP00000494162.1 RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGGTGCCC CTTTCGGCTC CTCCATTGCC CCCACGGCCA 
GATCTGCCCC CCAGGAAGCC CAGAAATGCC CAGCCGAAAG TGAGACTCCT AAAGGGGAAC 
TCCCCTCCAG CTGCGCTGGG ACCCCAGGAC CCTGCCCCGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036248.3
CDS	43..1467
Translation	MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA

Target ORF information:

RefSeq Version	NM_012116.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012116.4

ORF Insert Sequence:

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGGTGCCC CTTTCGGCTC CTCCATTGCC CCCACGGCCA 
GATCTGCCCC CCAGGAAGCC CAGAAATGCC CAGCCGAAAG TGAGACTCCT AAAGGGGAAC 
TCCCCTCCAG CTGCGCTGGG ACCCCAGGAC CCTGCCCCGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBLC ( NM_012116.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036248.3 Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06057
Clone ID Related Accession (Same CDS sequence)	NM_012116.4 , NM_012116.3
Accession Version	NM_012116.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL-C isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF117646.1, BC028915.1 and BF835530.1. This sequence is a reference standard in the RefSeqGene project. On Aug 6, 2008 this sequence version replaced NM_012116.2. Transcript Variant: This variant (1) represents the longer transcript and encodes protein isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF117646.1, AB028645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGGTGCCC CTTTCGGCTC CTCCATTGCC CCCACGGCCA 
GATCTGCCCC CCAGGAAGCC CAGAAATGCC CAGCCGAAAG TGAGACTCCT AAAGGGGAAC 
TCCCCTCCAG CTGCGCTGGG ACCCCAGGAC CCTGCCCCGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036248.3
CDS	64..1488
Translation	MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA

Target ORF information:

RefSeq Version	NM_012116.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012116.3

ORF Insert Sequence:

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGGTGCCC CTTTCGGCTC CTCCATTGCC CCCACGGCCA 
GATCTGCCCC CCAGGAAGCC CAGAAATGCC CAGCCGAAAG TGAGACTCCT AAAGGGGAAC 
TCCCCTCCAG CTGCGCTGGG ACCCCAGGAC CCTGCCCCGG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBLC ( NM_001130852.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124324.1 Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07090
Clone ID Related Accession (Same CDS sequence)	NM_001130852.1
Accession Version	NM_001130852.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1287bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL-C isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF117647.1, BC028915.1 and BF835530.1. Transcript Variant: This variant (2) omits an in-frame coding exon compared to variant 1, resulting in a shorter protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF117647.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGC 
TACCTCTACC CAGATGGAAA GACCCACAAC CCAGACCTGA CTGAGCTCGG CCAGGCAGAA 
CCCCAGCAGC GCATCCACGT GTCAGAGGAG CAGCTGCAGC TCTACTGGGC CATGGACTCC 
ACATTTGAGC TCTGCAAGAT CTGTGCTGAG AGCAACAAGG ATGTGAAGAT TGAGCCGTGC 
GGGCACCTGC TCTGCAGCTG CTGCCTGGCT GCCTGGCAGC ACTCGGACAG CCAGACCTGC 
CCCTTCTGCC GCTGCGAGAT CAAGGGCTGG GAGGCCGTGA GTATCTACCA GTTCCACGGT 
CAGGCTACTG CTGAGGACTC AGGGAACAGC AGTGACCAGG AAGGCAGGGA GTTGGAGCTG 
GGGCAGGTGC CCCTTTCGGC TCCTCCATTG CCCCCACGGC CAGATCTGCC CCCCAGGAAG 
CCCAGAAATG CCCAGCCGAA AGTGAGACTC CTAAAGGGGA ACTCCCCTCC AGCTGCGCTG 
GGACCCCAGG ACCCTGCCCC GGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124324.1
CDS	64..1350
Translation	MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA

Target ORF information:

RefSeq Version	NM_001130852.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130852.1

ORF Insert Sequence:

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGC 
TACCTCTACC CAGATGGAAA GACCCACAAC CCAGACCTGA CTGAGCTCGG CCAGGCAGAA 
CCCCAGCAGC GCATCCACGT GTCAGAGGAG CAGCTGCAGC TCTACTGGGC CATGGACTCC 
ACATTTGAGC TCTGCAAGAT CTGTGCTGAG AGCAACAAGG ATGTGAAGAT TGAGCCGTGC 
GGGCACCTGC TCTGCAGCTG CTGCCTGGCT GCCTGGCAGC ACTCGGACAG CCAGACCTGC 
CCCTTCTGCC GCTGCGAGAT CAAGGGCTGG GAGGCCGTGA GTATCTACCA GTTCCACGGT 
CAGGCTACTG CTGAGGACTC AGGGAACAGC AGTGACCAGG AAGGCAGGGA GTTGGAGCTG 
GGGCAGGTGC CCCTTTCGGC TCCTCCATTG CCCCCACGGC CAGATCTGCC CCCCAGGAAG 
CCCAGAAATG CCCAGCCGAA AGTGAGACTC CTAAAGGGGA ACTCCCCTCC AGCTGCGCTG 
GGACCCCAGG ACCCTGCCCC GGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBLC ( XM_005258696.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005258753.1 Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X3, mRNA.

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CloneID	OHu52144
Clone ID Related Accession (Same CDS sequence)	XM_005258696.3
Accession Version	XM_005258696.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL-C isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005258696.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGAACAGT GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258753.1
CDS	71..1366
Translation	MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQNSA

Target ORF information:

RefSeq Version	XM_005258696.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258696.3

ORF Insert Sequence:

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGAACAGT GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBLC ( XM_011526688.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524990.1 Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X1, mRNA.

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CloneID	OHu66364
Clone ID Related Accession (Same CDS sequence)	XM_011526688.2
Accession Version	XM_011526688.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL-C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526688.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGGTGCCC CTTTCGGCTC CTCCATTGCC CCCACGGCCA 
GATCTGCCCC CCAGGAAGCC CAGAAATGCC CAGCCGAAAG TGGCACTTTT GGCCCTCCCC 
AGACTTCGGG CCCCTCTTCT CTTGCCAAGA ATTAAGGCTG TGGCCTCAGC CGCGCAGGAA 
GCCACCTCCA GCCCCCAGGT GGTCTGGGAC TCCCAGGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524990.1
CDS	72..1553
Translation	MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVALLALPRLRAPLLLPRIKAVASAAQEATSSPQVVWDSQV

Target ORF information:

RefSeq Version	XM_011526688.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526688.2

ORF Insert Sequence:

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGT 
TACATCTTCC GGCCCAGCTG TACTCGCCTG GGGCAGTGGG CCATCGGCTA TGTGAGCTCA 
GATGGCAGCA TCCTGCAGAC CATCCCTGCC AACAAACCCC TGTCCCAGGT GCTCCTGGAG 
GGACAGAAGG ACGGCTTCTA CCTCTACCCA GATGGAAAGA CCCACAACCC AGACCTGACT 
GAGCTCGGCC AGGCAGAACC CCAGCAGCGC ATCCACGTGT CAGAGGAGCA GCTGCAGCTC 
TACTGGGCCA TGGACTCCAC ATTTGAGCTC TGCAAGATCT GTGCTGAGAG CAACAAGGAT 
GTGAAGATTG AGCCGTGCGG GCACCTGCTC TGCAGCTGCT GCCTGGCTGC CTGGCAGCAC 
TCGGACAGCC AGACCTGCCC CTTCTGCCGC TGCGAGATCA AGGGCTGGGA GGCCGTGAGT 
ATCTACCAGT TCCACGGTCA GGCTACTGCT GAGGACTCAG GGAACAGCAG TGACCAGGAA 
GGCAGGGAGT TGGAGCTGGG GCAGGTGCCC CTTTCGGCTC CTCCATTGCC CCCACGGCCA 
GATCTGCCCC CCAGGAAGCC CAGAAATGCC CAGCCGAAAG TGGCACTTTT GGCCCTCCCC 
AGACTTCGGG CCCCTCTTCT CTTGCCAAGA ATTAAGGCTG TGGCCTCAGC CGCGCAGGAA 
GCCACCTCCA GCCCCCAGGT GGTCTGGGAC TCCCAGGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBLC ( XM_011526689.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524991.1 Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu66365
Clone ID Related Accession (Same CDS sequence)	XM_011526689.2
Accession Version	XM_011526689.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL-C isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526689.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGC 
TACCTCTACC CAGATGGAAA GACCCACAAC CCAGACCTGA CTGAGCTCGG CCAGGCAGAA 
CCCCAGCAGC GCATCCACGT GTCAGAGGAG CAGCTGCAGC TCTACTGGGC CATGGACTCC 
ACATTTGAGC TCTGCAAGAT CTGTGCTGAG AGCAACAAGG ATGTGAAGAT TGAGCCGTGC 
GGGCACCTGC TCTGCAGCTG CTGCCTGGCT GCCTGGCAGC ACTCGGACAG CCAGACCTGC 
CCCTTCTGCC GCTGCGAGAT CAAGGGCTGG GAGGCCGTGA GTATCTACCA GTTCCACGGT 
CAGGCTACTG CTGAGGACTC AGGGAACAGC AGTGACCAGG AAGGCAGGGA GTTGGAGCTG 
GGGCAGGTGC CCCTTTCGGC TCCTCCATTG CCCCCACGGC CAGATCTGCC CCCCAGGAAG 
CCCAGAAATG CCCAGCCGAA AGTGGCACTT TTGGCCCTCC CCAGACTTCG GGCCCCTCTT 
CTCTTGCCAA GAATTAAGGC TGTGGCCTCA GCCGCGCAGG AAGCCACCTC CAGCCCCCAG 
GTGGTCTGGG ACTCCCAGGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524991.1
CDS	74..1417
Translation	MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVALLALPRLRAPLLLPRIKAVASAAQEATSSPQVVWDSQV

Target ORF information:

RefSeq Version	XM_011526689.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526689.2

ORF Insert Sequence:

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGCCA 
TGGCCAACAC TCCTCAAGAA CTGGCAGCTC CTGGCAGTCA ACCACCCAGG CTACATGGCC 
TTCCTCACCT ATGATGAGGT CCAAGAGCGT CTGCAGGCCT GCAGGGACAA GCCAGGCAGC 
TACCTCTACC CAGATGGAAA GACCCACAAC CCAGACCTGA CTGAGCTCGG CCAGGCAGAA 
CCCCAGCAGC GCATCCACGT GTCAGAGGAG CAGCTGCAGC TCTACTGGGC CATGGACTCC 
ACATTTGAGC TCTGCAAGAT CTGTGCTGAG AGCAACAAGG ATGTGAAGAT TGAGCCGTGC 
GGGCACCTGC TCTGCAGCTG CTGCCTGGCT GCCTGGCAGC ACTCGGACAG CCAGACCTGC 
CCCTTCTGCC GCTGCGAGAT CAAGGGCTGG GAGGCCGTGA GTATCTACCA GTTCCACGGT 
CAGGCTACTG CTGAGGACTC AGGGAACAGC AGTGACCAGG AAGGCAGGGA GTTGGAGCTG 
GGGCAGGTGC CCCTTTCGGC TCCTCCATTG CCCCCACGGC CAGATCTGCC CCCCAGGAAG 
CCCAGAAATG CCCAGCCGAA AGTGGCACTT TTGGCCCTCC CCAGACTTCG GGCCCCTCTT 
CTCTTGCCAA GAATTAAGGC TGTGGCCTCA GCCGCGCAGG AAGCCACCTC CAGCCCCCAG 
GTGGTCTGGG ACTCCCAGGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CBLC ( XM_011526690.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524992.1 Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X5, mRNA.

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CloneID	OHu66366
Clone ID Related Accession (Same CDS sequence)	XM_011526690.2
Accession Version	XM_011526690.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase CBL-C isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526690.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGTTA 
CATCTTCCGG CCCAGCTGTA CTCGCCTGGG GCAGTGGGCC ATCGGCTATG TGAGCTCAGA 
TGGCAGCATC CTGCAGACCA TCCCTGCCAA CAAACCCCTG TCCCAGGTGC TCCTGGAGGG 
ACAGAAGGAC GGCTTGTGAG TCTCCATTCT GCTACCTCTA CCCAGATGGA AAGACCCACA 
ACCCAGACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524992.1
CDS	78..929
Translation	MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQLHLPAQLYSPGAVGHRLCELRWQHPADHPCQQTPVPGAPGGTEGRLVSLHSATSTQMERPTTQT

Target ORF information:

RefSeq Version	XM_011526690.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526690.2

ORF Insert Sequence:

ATGGCTCTGG CGGTGGCCCC GTGGGGGCGA CAGTGGGAAG AGGCCCGCGC CCTGGGCCGG 
GCAGTCAGGA TGCTGCAGCG CCTAGAAGAG CAATGCGTCG ACCCCCGGCT GTCCGTGAGT 
CCCCCTTCGC TGCGGGACCT GCTGCCCCGC ACAGCGCAGC TGCTTCGAGA GGTGGCCCAT 
TCTCGGCGGG CGGCCGGCGG AGGCGGCCCC GGGGGTCCCG GCGGCTCTGG GGACTTTCTA 
CTCATCTACC TGGCCAATCT GGAGGCCAAG AGCAGGCAGG TGGCCGCGCT GCTGCCTCCC 
CGGGGCCGAA GGAGTGCCAA CGACGAGCTC TTCCGGGCGG GCTCCAGACT CAGGCGACAG 
CTGGCCAAGC TGGCCATCAT CTTCAGCCAC ATGCACGCAG AGCTGCACGC ACTCTTCCCC 
GGGGGAAAGT ACTGTGGACA CATGTACCAG CTCACCAAGG CCCCCGCCCA CACCTTCTGG 
AGGGAAAGTT GCGGAGCCCG GTGTGTGCTG CCCTGGGCTG AGTTTGAGTC CCTCCTGGGC 
ACCTGCCACC CTGTGGAACC AGGCTGCACA GCCCTGGCCT TGCGCACCAC CATTGACCTC 
ACCTGCAGCG GGCACGTGTC CATCTTCGAG TTCGACGTCT TCACCAGGCT CTTTCAGTTA 
CATCTTCCGG CCCAGCTGTA CTCGCCTGGG GCAGTGGGCC ATCGGCTATG TGAGCTCAGA 
TGGCAGCATC CTGCAGACCA TCCCTGCCAA CAAACCCCTG TCCCAGGTGC TCCTGGAGGG 
ACAGAAGGAC GGCTTGTGAG TCTCCATTCT GCTACCTCTA CCCAGATGGA AAGACCCACA 
ACCCAGACCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Optical coherence tomography morphology and evolution in cblC disease-related maculopathy in a case series of very young patients.
Acta ophthalmologica95(8)e776-e782(2017 Dec)
Bacci GM,Donati MA,Pasquini E,Munier F,Cavicchi C,Morrone A,Sodi A,Murro V,Garcia Segarra N,Defilippi C,Bussolin L,Caputo R

Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.
The Journal of biological chemistry290(18)11393-402(2015 May)
Gherasim C,Ruetz M,Li Z,Hudolin S,Banerjee R

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity.
Oncotarget6(13)10746-58(2015 May)
Frankum J,Moudry P,Brough R,Hodny Z,Ashworth A,Bartek J,Lord CJ

The Ubiquitin Ligase CBLC Maintains the Network Organization of the Golgi Apparatus.
PloS one10(9)e0138789(2015)
Lee WY,Goh G,Chia J,Boey A,Gunko NV,Bard F

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CBLC cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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