Gene Symbol | WBP2 |
Entrez Gene ID | 23558 |
Full Name | WW domain binding protein 2 |
Synonyms | DFNB107,GRAMD6,WBP-2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. [provided by RefSeq, Jan 2017]. |
Disorder MIM: | |
Disorder Html: | Deafness, autosomal recessive 107, 617639 (3) |