PIK3R5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PIK3R5
Entrez Gene ID	23533
Full Name	phosphoinositide-3-kinase regulatory subunit 5
Synonyms	F730038I15Rik,FOAP-2,P101-PI3K,p101
General protein information	Preferred Names phosphoinositide-3-kinase regulatory subunit 5 Names phosphoinositide 3-kinase regulatory subunit 5 PI3-kinase p101 subunit phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit protein FOAP-2 ptdIns-3-kinase p101
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.1
Summary	Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011].
Disorder MIM:	611317
Disorder Html:	Ataxia-oculomotor apraxia 3, 615217 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001251851.1	NP_001238780.1	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
NM_001142633.2	NP_001136105.1	phosphoinositide 3-kinase regulatory subunit 5 isoform 1
NM_014308.3	NP_055123.2	phosphoinositide 3-kinase regulatory subunit 5 isoform 1
NM_001251855.1	NP_001238784.1	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
NM_001251852.1	NP_001238781.1	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
NM_001251851.2	NP_001238780.1	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
XM_005256580.3	XP_005256637.1	phosphoinositide 3-kinase regulatory subunit 5 isoform X1
NM_001251853.1	NP_001238782.1	phosphoinositide 3-kinase regulatory subunit 5 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PIK3R5	XP_002707807.1
Mus musculus (house mouse)	Pik3r5	NP_796294.2
Danio rerio (zebrafish)	pik3r5	XP_002662391.2
Canis lupus familiaris (dog)	PIK3R5	XP_850196.1
Gallus gallus (chicken)	PIK3R5	NP_001025868.1
Pan troglodytes (chimpanzee)	PIK3R5	XP_001165933.3
	PIK3R5	XP_001118227.2
Rattus norvegicus (Norway rat)	Pik3r5	NP_001178852.1
Xenopus tropicalis (tropical clawed frog)	pik3r5	NP_001039143.1
Homo sapiens (human)	PIK3R5	NP_055123.2

Gene Ontology
Bibliography

Related articles in PubMed

Different inhibition of G??-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a G??-dependent regulator of PI3K? enzymatic activity.
Shymanets A, Prajwal, Vadas O, Czupalla C, LoPiccolo J, Brenowitz M, Ghigo A, Hirsch E, Krause E, Wetzker R, Williams RL, Harteneck C, N?rnberg B
The Biochemical journal469(1)59-69(2015 Jul)

Screening of differential promoter hypermethylated genes in primary oral squamous cell carcinoma.
Khor GH, Froemming GR, Zain RB, Abraham MT, Thong KL
Asian Pacific journal of cancer prevention : APJCP15(20)8957-61(2014)

p87 and p101 subunits are distinct regulators determining class IB phosphoinositide 3-kinase (PI3K) specificity.
Shymanets A, Prajwal, Bucher K, Beer-Hammer S, Harteneck C, N?rnberg B
The Journal of biological chemistry288(43)31059-68(2013 Oct)

A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia.
Al Tassan N, Khalil D, Shinwari J, Al Sharif L, Bavi P, Abduljaleel Z, Abu Dhaim N, Magrashi A, Bobis S, Ahmed H, Alahmed S, Bohlega S
Human mutation33(2)351-4(2012 Feb)

Phosphatidylinositol 3-kinase: the oncoprotein.
Vogt PK, Hart JR, Gymnopoulos M, Jiang H, Kang S, Bader AG, Zhao L, Denley A
Current topics in microbiology and immunology34779-104(2010)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data argue for differential regulatory functions of the non-catalytic subunits and a specific Gbetagamma-dependent regulation of p101 in PI3Kgamma activation.
Title: Different inhibition of G??-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a G??-dependent regulator of PI3K? enzymatic activity.

PIK3R5 promoter hypermethylation is associated with oral squamous cell carcinoma.
Title: Screening of differential promoter hypermethylated genes in primary oral squamous cell carcinoma.

expression and activities of PI3Kgamma are modified differently by p87 and p101 in vitro and in living cells, arguing for specific regulatory roles of the non-catalytic subunits in the differentiation of PI3Kgamma signaling pathways.
Title: p87 and p101 subunits are distinct regulators determining class IB phosphoinositide 3-kinase (PI3K) specificity.

Our characterization of the PIK3R5 protein and findings suggest that it may play a role in the development of the cerebellum and vermis.
Title: A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following PIK3R5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PIK3R5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02430	NM_001251851.2 Latest version!	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02430	NM_001251855.1 Latest version!	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02430	NM_001251853.1 Latest version!	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02430	NM_001251852.1 Latest version!	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu06304	NM_014308.3 Latest version!	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu06304	NM_001142633.2 Latest version!	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu49794	XM_005256580.3 Latest version!	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu02430	NM_001251851.1	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PIK3R5 ( NM_001251851.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238780.1 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu02430
Clone ID Related Accession (Same CDS sequence)	NM_001251851.1 , NM_001251855.1 , NM_001251852.1 , NM_001251851.2 , NM_001251853.1
Accession Version	NM_001251851.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309074.1, AY725851.1, AF128881.1 and BC028212.1. On Aug 31, 2013 this sequence version replaced XM_005256581.1. Transcript Variant: This variant (3) has an additional segment in an internal region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 3-6 encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC028212.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238780.1
CDS	1351..2835
Translation	MDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	NM_001251851.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251851.1

ORF Insert Sequence:

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIK3R5 ( NM_001251855.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238784.1 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu02430
Clone ID Related Accession (Same CDS sequence)	NM_001251851.1 , NM_001251855.1 , NM_001251852.1 , NM_001251851.2 , NM_001251853.1
Accession Version	NM_001251855.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309074.1, BC028212.1 and AF128881.1. Transcript Variant: This variant (6) lacks an exon in an internal region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 3-6 encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC028212.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238784.1
CDS	1114..2598
Translation	MDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	NM_001251855.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251855.1

ORF Insert Sequence:

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIK3R5 ( NM_001251852.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238781.1 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu02430
Clone ID Related Accession (Same CDS sequence)	NM_001251851.1 , NM_001251855.1 , NM_001251852.1 , NM_001251851.2 , NM_001251853.1
Accession Version	NM_001251852.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309074.1, AF128881.1 and BC028212.1. Transcript Variant: This variant (4) lacks an exon in the 5' region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 3-6 encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC028212.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238781.1
CDS	1173..2657
Translation	MDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	NM_001251852.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251852.1

ORF Insert Sequence:

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIK3R5 ( NM_001251851.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238780.1 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 3, mRNA.

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CloneID	OHu02430
Clone ID Related Accession (Same CDS sequence)	NM_001251851.1 , NM_001251855.1 , NM_001251852.1 , NM_001251851.2 , NM_001251853.1
Accession Version	NM_001251851.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309074.1, AY725851.1, AF128881.1 and BC028212.1. On Jun 2, 2019 this sequence version replaced NM_001251851.1. Transcript Variant: This variant (3) has an additional segment in an internal region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 3-6 encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238780.1
CDS	1346..2830
Translation	MDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	NM_001251851.2
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251851.2

ORF Insert Sequence:

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIK3R5 ( NM_001251853.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001238782.1 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 5, mRNA.

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CloneID	OHu02430
Clone ID Related Accession (Same CDS sequence)	NM_001251851.1 , NM_001251855.1 , NM_001251852.1 , NM_001251851.2 , NM_001251853.1
Accession Version	NM_001251853.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309074.1, AY725852.1, BC028212.1, AB028925.1 and AF128881.1. Transcript Variant: This variant (5) lacks an exon in an internal region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 3-6 encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC028212.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001238782.1
CDS	1135..2619
Translation	MDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	NM_001251853.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001251853.1

ORF Insert Sequence:

ATGGACAGCG GCTACGTGGA GGACAGCGAG GAGAGCTCCT CCGAGTGGCC TTGGAGGCGT 
GGCAGCCAGG AACGCCGAGG CCACCGCAGG CCTGGGCAGA AGTTCATCAG GATCTATAAA 
CTCTTCAAGA GCACCAGCCA GCTGGTACTG CGGAGGGACT CTCGGAGCCT GGAGGGCAGC 
TCGGACACGG CCCTGCCCCT GAGGCGGGCA GGGAGCCTCT GCAGCCCCCT GGACGAACCA 
GTATCACCCC CTTCCCGGGC CCAGCGCTCC CGCTCCCTGC CCCAGCCCAA ACTCGGTACC 
CAGCTGCCCA GCTGGCTTCT GGCCCCTGCT TCACGCCCCC AGCGCCGCCG CCCCTTCCTG 
AGTGGAGATG AGGATCCCAA GGCTTCCACG CTACGTGTTG TGGTCTTTGG CTCCGATCGG 
ATTTCAGGGA AGGTGGCTCG GGCGTACAGC AACCTTCGGC GGCTGGAGAA CAATCGCCCA 
CTCCTCACAC GGTTCTTCAA ACTTCAGTTC TTCTACGTGC CTGTGAAGCG AAGTCATGGG 
ACCAGCCCTG GTGCCTGTCC ACCCCCTCGG AGCCAGACGC CCTCACCCCC GACAGACTCC 
CCTAGGCACG CCAGCCCTGG AGAGCTGGGC ACCACCCCAT GGGAGGAGAG CACCAATGAC 
ATCTCCCACT ACCTCGGCAT GCTGGACCCC TGGTATGAGC GCAATGTACT GGGCCTCATG 
CACCTGCCCC CTGAAGTCCT GTGCCAGCAG TCCCTGAAGG CTGAAGCCCA GGCCCTGGAG 
GGCTCCCCAA CCCAGCTGCC CATCCTGGCT GACATGCTAC TCTACTACTG CCGCTTTGCC 
GCCAGACCGG TGCTGCTGCA AGTCTATCAG ACCGAGCTGA CCTTCATCAC TGGGGAGAAG 
ACGACAGAGA TCTTCATCCA CTCCTTGGAG CTGGGTCACT CCGCTGCCAC ACGTGCCATC 
AAGGCGTCAG GTCCTGGCAG CAAGCGGCTG GGCATCGATG GCGACCGGGA GGCTGTTCCT 
CTAACACTAC AGATTATTTA CAGCAAGGGG GCCATCAGTG GACGAAGTCG CTGGAGCAAC 
CTGGAGAAGG TCTGTACCTC CGTGAACCTC AACAAGGCCT GCCGGAAGCA GGAGGAGCTG 
GATTCCAGCA TGGAGGCCCT GACGCTAAAC CTGACAGAAG TGGTGAAAAG GCAGAACTCC 
AAATCCAAGA AGGGCTTTAA CCAGATTAGC ACATCGCAGA TCAAAGTGGA CAAGGTGCAG 
ATCATCGGCT CCAACAGCTG CCCCTTTGCT GTGTGCCTGG ACCAGGATGA GAGAAAGATC 
CTGCAGAGTG TAGTCAGATG TGAGGTCTCA CCGTGCTACA AGCCAGAGAA GAGCGACCTC 
TCCTCACCAC CCCAGACGCC TCCTGACCTG CCGGCCCAGG CCGCACCTGA TCTCTGCTCC 
CTTCTCTGCC TGCCCATCAT GACTTTCAGT GGAGCTCTGC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIK3R5 ( NM_001142633.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001136105.1 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06304
Clone ID Related Accession (Same CDS sequence)	NM_001142633.2 , NM_014308.3
Accession Version	NM_001142633.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2643bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309074.1, AY725854.1, AB028925.1 and BC028212.1. This sequence is a reference standard in the RefSeqGene project. On Oct 21, 2011 this sequence version replaced NM_001142633.1. Transcript Variant: This variant (1) and variant 2 encode the same protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF128881.1, AB028925.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGCAGCCAG GGGCCACGAC ATGCACGGAG GACCGCATCC AGCATGCCCT GGAACGCTGC 
CTGCATGGAC TCAGCCTCAG CCGCCGCTCC ACCTCCTGGT CAGCTGGGCT GTGTCTGAAC 
TGCTGGAGCC TGCAGGAGCT GGTCAGCAGG GACCCGGGCC ACTTCCTTAT CCTCCTTGAG 
CAGATCCTGC AGAAGACCCG AGAGGTCCAG GAGAAGGGCA CCTACGACCT GCTCACCCCG 
CTGGCCCTGC TCTTCTATTC CACTGTTCTT TGTACACCAC ACTTCCCACC AGACTCGGAT 
CTCCTTCTGA AGGCAGCCAG CACCTACCAC CGGTTCCTGA CCTGGCCTGT TCCTTACTGC 
AGCATCTGCC AGGAGCTGCT CACCTTCATT GATGCTGAAC TCAAGGCCCC AGGGATCTCC 
TACCAGAGAC TGGTGAGGGC TGAGCAGGGC CTGCCCATCA GGAGTCACCG CAGCTCCACC 
GTCACCGTGC TGCTGCTGAA CCCAGTGGAA GTGCAGGCCG AGTTCCTTGC TGTAGCCAAT 
AAGCTGAGTA CGCCCGGACA CTCGCCTCAC AGTGCCTACA CCACCCTGCT CCTGCACGCC 
TTCCAGGCCA CCTTTGGGGC CCACTGTGAC GTCCCGGGCC TGCACTGCAG GCTACAGGCC 
AAGACCCTGG CAGAGCTTGA GGACATCTTC ACGGAGACCG CAGAGGCACA GGAGCTGGCA 
TCTGGCATCG GGGATGCTGC AGAGGCCCGG CGGTGGCTCA GGACCAAGCT GCAGGCGGTG 
GGAGAAAAAG CTGGCTTCCC TGGGGTGTTA GACACTGCAA AACCAGGGAA GCTCCACACC 
ATCCCCATCC CTGTCGCCAG GTGCTACACC TACAGCTGGA GCCAGGACAG CTTTGACATC 
CTGCAGGAAA TCCTGCTCAA GGAACAGGAG CTACTCCAGC CAGGGATCCT GGGAGATGAT 
GAAGAGGAGG AAGAGGAGGA GGAGGAGGTG GAGGAGGACT TGGAAACTGA CGGGCACTGT 
GCCGAGAGAG ATTCCCTGCT CTCCACCAGC TCTTTGGCGT CCCATGACTC CACCTTGTCC 
CTTGCATCCT CCCAGGCCTC GGGGCCGGCC CTCTCGCGCC ATCTGCTGAC TTCCTTTGTC 
TCAGGCCTCT CTGATGGCAT GGACAGCGGC TACGTGGAGG ACAGCGAGGA GAGCTCCTCC 
GAGTGGCCTT GGAGGCGTGG CAGCCAGGAA CGCCGAGGCC ACCGCAGGCC TGGGCAGAAG 
TTCATCAGGA TCTATAAACT CTTCAAGAGC ACCAGCCAGC TGGTACTGCG GAGGGACTCT 
CGGAGCCTGG AGGGCAGCTC GGACACGGCC CTGCCCCTGA GGCGGGCAGG GAGCCTCTGC 
AGCCCCCTGG ACGAACCAGT ATCACCCCCT TCCCGGGCCC AGCGCTCCCG CTCCCTGCCC 
CAGCCCAAAC TCGGTACCCA GCTGCCCAGC TGGCTTCTGG CCCCTGCTTC ACGCCCCCAG 
CGCCGCCGCC CCTTCCTGAG TGGAGATGAG GATCCCAAGG CTTCCACGCT ACGTGTTGTG 
GTCTTTGGCT CCGATCGGAT TTCAGGGAAG GTGGCTCGGG CGTACAGCAA CCTTCGGCGG 
CTGGAGAACA ATCGCCCACT CCTCACACGG TTCTTCAAAC TTCAGTTCTT CTACGTGCCT 
GTGAAGCGAA GTCATGGGAC CAGCCCTGGT GCCTGTCCAC CCCCTCGGAG CCAGACGCCC 
TCACCCCCGA CAGACTCCCC TAGGCACGCC AGCCCTGGAG AGCTGGGCAC CACCCCATGG 
GAGGAGAGCA CCAATGACAT CTCCCACTAC CTCGGCATGC TGGACCCCTG GTATGAGCGC 
AATGTACTGG GCCTCATGCA CCTGCCCCCT GAAGTCCTGT GCCAGCAGTC CCTGAAGGCT 
GAAGCCCAGG CCCTGGAGGG CTCCCCAACC CAGCTGCCCA TCCTGGCTGA CATGCTACTC 
TACTACTGCC GCTTTGCCGC CAGACCGGTG CTGCTGCAAG TCTATCAGAC CGAGCTGACC 
TTCATCACTG GGGAGAAGAC GACAGAGATC TTCATCCACT CCTTGGAGCT GGGTCACTCC 
GCTGCCACAC GTGCCATCAA GGCGTCAGGT CCTGGCAGCA AGCGGCTGGG CATCGATGGC 
GACCGGGAGG CTGTTCCTCT AACACTACAG ATTATTTACA GCAAGGGGGC CATCAGTGGA 
CGAAGTCGCT GGAGCAACCT GGAGAAGGTC TGTACCTCCG TGAACCTCAA CAAGGCCTGC 
CGGAAGCAGG AGGAGCTGGA TTCCAGCATG GAGGCCCTGA CGCTAAACCT GACAGAAGTG 
GTGAAAAGGC AGAACTCCAA ATCCAAGAAG GGCTTTAACC AGATTAGCAC ATCGCAGATC 
AAAGTGGACA AGGTGCAGAT CATCGGCTCC AACAGCTGCC CCTTTGCTGT GTGCCTGGAC 
CAGGATGAGA GAAAGATCCT GCAGAGTGTA GTCAGATGTG AGGTCTCACC GTGCTACAAG 
CCAGAGAAGA GCGACCTCTC CTCACCACCC CAGACGCCTC CTGACCTGCC GGCCCAGGCC 
GCACCTGATC TCTGCTCCCT TCTCTGCCTG CCCATCATGA CTTTCAGTGG AGCTCTGCCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136105.1
CDS	131..2773
Translation	MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVANKLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELASGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDILQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	NM_001142633.2
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142633.2

ORF Insert Sequence:

ATGCAGCCAG GGGCCACGAC ATGCACGGAG GACCGCATCC AGCATGCCCT GGAACGCTGC 
CTGCATGGAC TCAGCCTCAG CCGCCGCTCC ACCTCCTGGT CAGCTGGGCT GTGTCTGAAC 
TGCTGGAGCC TGCAGGAGCT GGTCAGCAGG GACCCGGGCC ACTTCCTTAT CCTCCTTGAG 
CAGATCCTGC AGAAGACCCG AGAGGTCCAG GAGAAGGGCA CCTACGACCT GCTCACCCCG 
CTGGCCCTGC TCTTCTATTC CACTGTTCTT TGTACACCAC ACTTCCCACC AGACTCGGAT 
CTCCTTCTGA AGGCAGCCAG CACCTACCAC CGGTTCCTGA CCTGGCCTGT TCCTTACTGC 
AGCATCTGCC AGGAGCTGCT CACCTTCATT GATGCTGAAC TCAAGGCCCC AGGGATCTCC 
TACCAGAGAC TGGTGAGGGC TGAGCAGGGC CTGCCCATCA GGAGTCACCG CAGCTCCACC 
GTCACCGTGC TGCTGCTGAA CCCAGTGGAA GTGCAGGCCG AGTTCCTTGC TGTAGCCAAT 
AAGCTGAGTA CGCCCGGACA CTCGCCTCAC AGTGCCTACA CCACCCTGCT CCTGCACGCC 
TTCCAGGCCA CCTTTGGGGC CCACTGTGAC GTCCCGGGCC TGCACTGCAG GCTACAGGCC 
AAGACCCTGG CAGAGCTTGA GGACATCTTC ACGGAGACCG CAGAGGCACA GGAGCTGGCA 
TCTGGCATCG GGGATGCTGC AGAGGCCCGG CGGTGGCTCA GGACCAAGCT GCAGGCGGTG 
GGAGAAAAAG CTGGCTTCCC TGGGGTGTTA GACACTGCAA AACCAGGGAA GCTCCACACC 
ATCCCCATCC CTGTCGCCAG GTGCTACACC TACAGCTGGA GCCAGGACAG CTTTGACATC 
CTGCAGGAAA TCCTGCTCAA GGAACAGGAG CTACTCCAGC CAGGGATCCT GGGAGATGAT 
GAAGAGGAGG AAGAGGAGGA GGAGGAGGTG GAGGAGGACT TGGAAACTGA CGGGCACTGT 
GCCGAGAGAG ATTCCCTGCT CTCCACCAGC TCTTTGGCGT CCCATGACTC CACCTTGTCC 
CTTGCATCCT CCCAGGCCTC GGGGCCGGCC CTCTCGCGCC ATCTGCTGAC TTCCTTTGTC 
TCAGGCCTCT CTGATGGCAT GGACAGCGGC TACGTGGAGG ACAGCGAGGA GAGCTCCTCC 
GAGTGGCCTT GGAGGCGTGG CAGCCAGGAA CGCCGAGGCC ACCGCAGGCC TGGGCAGAAG 
TTCATCAGGA TCTATAAACT CTTCAAGAGC ACCAGCCAGC TGGTACTGCG GAGGGACTCT 
CGGAGCCTGG AGGGCAGCTC GGACACGGCC CTGCCCCTGA GGCGGGCAGG GAGCCTCTGC 
AGCCCCCTGG ACGAACCAGT ATCACCCCCT TCCCGGGCCC AGCGCTCCCG CTCCCTGCCC 
CAGCCCAAAC TCGGTACCCA GCTGCCCAGC TGGCTTCTGG CCCCTGCTTC ACGCCCCCAG 
CGCCGCCGCC CCTTCCTGAG TGGAGATGAG GATCCCAAGG CTTCCACGCT ACGTGTTGTG 
GTCTTTGGCT CCGATCGGAT TTCAGGGAAG GTGGCTCGGG CGTACAGCAA CCTTCGGCGG 
CTGGAGAACA ATCGCCCACT CCTCACACGG TTCTTCAAAC TTCAGTTCTT CTACGTGCCT 
GTGAAGCGAA GTCATGGGAC CAGCCCTGGT GCCTGTCCAC CCCCTCGGAG CCAGACGCCC 
TCACCCCCGA CAGACTCCCC TAGGCACGCC AGCCCTGGAG AGCTGGGCAC CACCCCATGG 
GAGGAGAGCA CCAATGACAT CTCCCACTAC CTCGGCATGC TGGACCCCTG GTATGAGCGC 
AATGTACTGG GCCTCATGCA CCTGCCCCCT GAAGTCCTGT GCCAGCAGTC CCTGAAGGCT 
GAAGCCCAGG CCCTGGAGGG CTCCCCAACC CAGCTGCCCA TCCTGGCTGA CATGCTACTC 
TACTACTGCC GCTTTGCCGC CAGACCGGTG CTGCTGCAAG TCTATCAGAC CGAGCTGACC 
TTCATCACTG GGGAGAAGAC GACAGAGATC TTCATCCACT CCTTGGAGCT GGGTCACTCC 
GCTGCCACAC GTGCCATCAA GGCGTCAGGT CCTGGCAGCA AGCGGCTGGG CATCGATGGC 
GACCGGGAGG CTGTTCCTCT AACACTACAG ATTATTTACA GCAAGGGGGC CATCAGTGGA 
CGAAGTCGCT GGAGCAACCT GGAGAAGGTC TGTACCTCCG TGAACCTCAA CAAGGCCTGC 
CGGAAGCAGG AGGAGCTGGA TTCCAGCATG GAGGCCCTGA CGCTAAACCT GACAGAAGTG 
GTGAAAAGGC AGAACTCCAA ATCCAAGAAG GGCTTTAACC AGATTAGCAC ATCGCAGATC 
AAAGTGGACA AGGTGCAGAT CATCGGCTCC AACAGCTGCC CCTTTGCTGT GTGCCTGGAC 
CAGGATGAGA GAAAGATCCT GCAGAGTGTA GTCAGATGTG AGGTCTCACC GTGCTACAAG 
CCAGAGAAGA GCGACCTCTC CTCACCACCC CAGACGCCTC CTGACCTGCC GGCCCAGGCC 
GCACCTGATC TCTGCTCCCT TCTCTGCCTG CCCATCATGA CTTTCAGTGG AGCTCTGCCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIK3R5 ( NM_014308.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055123.2 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 2, mRNA.

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CloneID	OHu06304
Clone ID Related Accession (Same CDS sequence)	NM_001142633.2 , NM_014308.3
Accession Version	NM_014308.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2643bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF128881.1 and BC028212.1. On Dec 12, 2008 this sequence version replaced NM_014308.2. Transcript Variant: This variant (2) differs in the 5' UTR exon, compared to variant 1. Both variants 1 and 2 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF128881.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGCAGCCAG GGGCCACGAC ATGCACGGAG GACCGCATCC AGCATGCCCT GGAACGCTGC 
CTGCATGGAC TCAGCCTCAG CCGCCGCTCC ACCTCCTGGT CAGCTGGGCT GTGTCTGAAC 
TGCTGGAGCC TGCAGGAGCT GGTCAGCAGG GACCCGGGCC ACTTCCTTAT CCTCCTTGAG 
CAGATCCTGC AGAAGACCCG AGAGGTCCAG GAGAAGGGCA CCTACGACCT GCTCACCCCG 
CTGGCCCTGC TCTTCTATTC CACTGTTCTT TGTACACCAC ACTTCCCACC AGACTCGGAT 
CTCCTTCTGA AGGCAGCCAG CACCTACCAC CGGTTCCTGA CCTGGCCTGT TCCTTACTGC 
AGCATCTGCC AGGAGCTGCT CACCTTCATT GATGCTGAAC TCAAGGCCCC AGGGATCTCC 
TACCAGAGAC TGGTGAGGGC TGAGCAGGGC CTGCCCATCA GGAGTCACCG CAGCTCCACC 
GTCACCGTGC TGCTGCTGAA CCCAGTGGAA GTGCAGGCCG AGTTCCTTGC TGTAGCCAAT 
AAGCTGAGTA CGCCCGGACA CTCGCCTCAC AGTGCCTACA CCACCCTGCT CCTGCACGCC 
TTCCAGGCCA CCTTTGGGGC CCACTGTGAC GTCCCGGGCC TGCACTGCAG GCTACAGGCC 
AAGACCCTGG CAGAGCTTGA GGACATCTTC ACGGAGACCG CAGAGGCACA GGAGCTGGCA 
TCTGGCATCG GGGATGCTGC AGAGGCCCGG CGGTGGCTCA GGACCAAGCT GCAGGCGGTG 
GGAGAAAAAG CTGGCTTCCC TGGGGTGTTA GACACTGCAA AACCAGGGAA GCTCCACACC 
ATCCCCATCC CTGTCGCCAG GTGCTACACC TACAGCTGGA GCCAGGACAG CTTTGACATC 
CTGCAGGAAA TCCTGCTCAA GGAACAGGAG CTACTCCAGC CAGGGATCCT GGGAGATGAT 
GAAGAGGAGG AAGAGGAGGA GGAGGAGGTG GAGGAGGACT TGGAAACTGA CGGGCACTGT 
GCCGAGAGAG ATTCCCTGCT CTCCACCAGC TCTTTGGCGT CCCATGACTC CACCTTGTCC 
CTTGCATCCT CCCAGGCCTC GGGGCCGGCC CTCTCGCGCC ATCTGCTGAC TTCCTTTGTC 
TCAGGCCTCT CTGATGGCAT GGACAGCGGC TACGTGGAGG ACAGCGAGGA GAGCTCCTCC 
GAGTGGCCTT GGAGGCGTGG CAGCCAGGAA CGCCGAGGCC ACCGCAGGCC TGGGCAGAAG 
TTCATCAGGA TCTATAAACT CTTCAAGAGC ACCAGCCAGC TGGTACTGCG GAGGGACTCT 
CGGAGCCTGG AGGGCAGCTC GGACACGGCC CTGCCCCTGA GGCGGGCAGG GAGCCTCTGC 
AGCCCCCTGG ACGAACCAGT ATCACCCCCT TCCCGGGCCC AGCGCTCCCG CTCCCTGCCC 
CAGCCCAAAC TCGGTACCCA GCTGCCCAGC TGGCTTCTGG CCCCTGCTTC ACGCCCCCAG 
CGCCGCCGCC CCTTCCTGAG TGGAGATGAG GATCCCAAGG CTTCCACGCT ACGTGTTGTG 
GTCTTTGGCT CCGATCGGAT TTCAGGGAAG GTGGCTCGGG CGTACAGCAA CCTTCGGCGG 
CTGGAGAACA ATCGCCCACT CCTCACACGG TTCTTCAAAC TTCAGTTCTT CTACGTGCCT 
GTGAAGCGAA GTCATGGGAC CAGCCCTGGT GCCTGTCCAC CCCCTCGGAG CCAGACGCCC 
TCACCCCCGA CAGACTCCCC TAGGCACGCC AGCCCTGGAG AGCTGGGCAC CACCCCATGG 
GAGGAGAGCA CCAATGACAT CTCCCACTAC CTCGGCATGC TGGACCCCTG GTATGAGCGC 
AATGTACTGG GCCTCATGCA CCTGCCCCCT GAAGTCCTGT GCCAGCAGTC CCTGAAGGCT 
GAAGCCCAGG CCCTGGAGGG CTCCCCAACC CAGCTGCCCA TCCTGGCTGA CATGCTACTC 
TACTACTGCC GCTTTGCCGC CAGACCGGTG CTGCTGCAAG TCTATCAGAC CGAGCTGACC 
TTCATCACTG GGGAGAAGAC GACAGAGATC TTCATCCACT CCTTGGAGCT GGGTCACTCC 
GCTGCCACAC GTGCCATCAA GGCGTCAGGT CCTGGCAGCA AGCGGCTGGG CATCGATGGC 
GACCGGGAGG CTGTTCCTCT AACACTACAG ATTATTTACA GCAAGGGGGC CATCAGTGGA 
CGAAGTCGCT GGAGCAACCT GGAGAAGGTC TGTACCTCCG TGAACCTCAA CAAGGCCTGC 
CGGAAGCAGG AGGAGCTGGA TTCCAGCATG GAGGCCCTGA CGCTAAACCT GACAGAAGTG 
GTGAAAAGGC AGAACTCCAA ATCCAAGAAG GGCTTTAACC AGATTAGCAC ATCGCAGATC 
AAAGTGGACA AGGTGCAGAT CATCGGCTCC AACAGCTGCC CCTTTGCTGT GTGCCTGGAC 
CAGGATGAGA GAAAGATCCT GCAGAGTGTA GTCAGATGTG AGGTCTCACC GTGCTACAAG 
CCAGAGAAGA GCGACCTCTC CTCACCACCC CAGACGCCTC CTGACCTGCC GGCCCAGGCC 
GCACCTGATC TCTGCTCCCT TCTCTGCCTG CCCATCATGA CTTTCAGTGG AGCTCTGCCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055123.2
CDS	68..2710
Translation	MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVANKLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELASGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDILQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	NM_014308.3
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014308.3

ORF Insert Sequence:

ATGCAGCCAG GGGCCACGAC ATGCACGGAG GACCGCATCC AGCATGCCCT GGAACGCTGC 
CTGCATGGAC TCAGCCTCAG CCGCCGCTCC ACCTCCTGGT CAGCTGGGCT GTGTCTGAAC 
TGCTGGAGCC TGCAGGAGCT GGTCAGCAGG GACCCGGGCC ACTTCCTTAT CCTCCTTGAG 
CAGATCCTGC AGAAGACCCG AGAGGTCCAG GAGAAGGGCA CCTACGACCT GCTCACCCCG 
CTGGCCCTGC TCTTCTATTC CACTGTTCTT TGTACACCAC ACTTCCCACC AGACTCGGAT 
CTCCTTCTGA AGGCAGCCAG CACCTACCAC CGGTTCCTGA CCTGGCCTGT TCCTTACTGC 
AGCATCTGCC AGGAGCTGCT CACCTTCATT GATGCTGAAC TCAAGGCCCC AGGGATCTCC 
TACCAGAGAC TGGTGAGGGC TGAGCAGGGC CTGCCCATCA GGAGTCACCG CAGCTCCACC 
GTCACCGTGC TGCTGCTGAA CCCAGTGGAA GTGCAGGCCG AGTTCCTTGC TGTAGCCAAT 
AAGCTGAGTA CGCCCGGACA CTCGCCTCAC AGTGCCTACA CCACCCTGCT CCTGCACGCC 
TTCCAGGCCA CCTTTGGGGC CCACTGTGAC GTCCCGGGCC TGCACTGCAG GCTACAGGCC 
AAGACCCTGG CAGAGCTTGA GGACATCTTC ACGGAGACCG CAGAGGCACA GGAGCTGGCA 
TCTGGCATCG GGGATGCTGC AGAGGCCCGG CGGTGGCTCA GGACCAAGCT GCAGGCGGTG 
GGAGAAAAAG CTGGCTTCCC TGGGGTGTTA GACACTGCAA AACCAGGGAA GCTCCACACC 
ATCCCCATCC CTGTCGCCAG GTGCTACACC TACAGCTGGA GCCAGGACAG CTTTGACATC 
CTGCAGGAAA TCCTGCTCAA GGAACAGGAG CTACTCCAGC CAGGGATCCT GGGAGATGAT 
GAAGAGGAGG AAGAGGAGGA GGAGGAGGTG GAGGAGGACT TGGAAACTGA CGGGCACTGT 
GCCGAGAGAG ATTCCCTGCT CTCCACCAGC TCTTTGGCGT CCCATGACTC CACCTTGTCC 
CTTGCATCCT CCCAGGCCTC GGGGCCGGCC CTCTCGCGCC ATCTGCTGAC TTCCTTTGTC 
TCAGGCCTCT CTGATGGCAT GGACAGCGGC TACGTGGAGG ACAGCGAGGA GAGCTCCTCC 
GAGTGGCCTT GGAGGCGTGG CAGCCAGGAA CGCCGAGGCC ACCGCAGGCC TGGGCAGAAG 
TTCATCAGGA TCTATAAACT CTTCAAGAGC ACCAGCCAGC TGGTACTGCG GAGGGACTCT 
CGGAGCCTGG AGGGCAGCTC GGACACGGCC CTGCCCCTGA GGCGGGCAGG GAGCCTCTGC 
AGCCCCCTGG ACGAACCAGT ATCACCCCCT TCCCGGGCCC AGCGCTCCCG CTCCCTGCCC 
CAGCCCAAAC TCGGTACCCA GCTGCCCAGC TGGCTTCTGG CCCCTGCTTC ACGCCCCCAG 
CGCCGCCGCC CCTTCCTGAG TGGAGATGAG GATCCCAAGG CTTCCACGCT ACGTGTTGTG 
GTCTTTGGCT CCGATCGGAT TTCAGGGAAG GTGGCTCGGG CGTACAGCAA CCTTCGGCGG 
CTGGAGAACA ATCGCCCACT CCTCACACGG TTCTTCAAAC TTCAGTTCTT CTACGTGCCT 
GTGAAGCGAA GTCATGGGAC CAGCCCTGGT GCCTGTCCAC CCCCTCGGAG CCAGACGCCC 
TCACCCCCGA CAGACTCCCC TAGGCACGCC AGCCCTGGAG AGCTGGGCAC CACCCCATGG 
GAGGAGAGCA CCAATGACAT CTCCCACTAC CTCGGCATGC TGGACCCCTG GTATGAGCGC 
AATGTACTGG GCCTCATGCA CCTGCCCCCT GAAGTCCTGT GCCAGCAGTC CCTGAAGGCT 
GAAGCCCAGG CCCTGGAGGG CTCCCCAACC CAGCTGCCCA TCCTGGCTGA CATGCTACTC 
TACTACTGCC GCTTTGCCGC CAGACCGGTG CTGCTGCAAG TCTATCAGAC CGAGCTGACC 
TTCATCACTG GGGAGAAGAC GACAGAGATC TTCATCCACT CCTTGGAGCT GGGTCACTCC 
GCTGCCACAC GTGCCATCAA GGCGTCAGGT CCTGGCAGCA AGCGGCTGGG CATCGATGGC 
GACCGGGAGG CTGTTCCTCT AACACTACAG ATTATTTACA GCAAGGGGGC CATCAGTGGA 
CGAAGTCGCT GGAGCAACCT GGAGAAGGTC TGTACCTCCG TGAACCTCAA CAAGGCCTGC 
CGGAAGCAGG AGGAGCTGGA TTCCAGCATG GAGGCCCTGA CGCTAAACCT GACAGAAGTG 
GTGAAAAGGC AGAACTCCAA ATCCAAGAAG GGCTTTAACC AGATTAGCAC ATCGCAGATC 
AAAGTGGACA AGGTGCAGAT CATCGGCTCC AACAGCTGCC CCTTTGCTGT GTGCCTGGAC 
CAGGATGAGA GAAAGATCCT GCAGAGTGTA GTCAGATGTG AGGTCTCACC GTGCTACAAG 
CCAGAGAAGA GCGACCTCTC CTCACCACCC CAGACGCCTC CTGACCTGCC GGCCCAGGCC 
GCACCTGATC TCTGCTCCCT TCTCTGCCTG CCCATCATGA CTTTCAGTGG AGCTCTGCCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIK3R5 ( XM_005256580.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256637.1 Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant X1, mRNA.

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CloneID	OHu49794
Clone ID Related Accession (Same CDS sequence)	XM_005256580.3
Accession Version	XM_005256580.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2640bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphoinositide 3-kinase regulatory subunit 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005256580.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCCAG GGGCCACGAC ATGCACGGAG GACCGCATCC AGCATGCCCT GGAACGCTGC 
CTGCATGGAC TCAGCCTCAG CCGCCGCTCC ACCTCCTGGT CAGCTGGGCT GTGTCTGAAC 
TGCTGGAGCC TGCAGGAGCT GGTCAGCAGG GACCCGGGCC ACTTCCTTAT CCTCCTTGAG 
CAGATCCTGC AGAAGACCCG AGAGGTCCAG GAGAAGGGCA CCTACGACCT GCTCACCCCG 
CTGGCCCTGC TCTTCTATTC CACTGTTCTT TGTACACCAC ACTTCCCACC AGACTCGGAT 
CTCCTTCTGA AGGCAGCCAG CACCTACCAC CGGTTCCTGA CCTGGCCTGT TCCTTACTGC 
AGCATCTGCC AGGAGCTGCT CACCTTCATT GATGCTGAAC TCAAGGCCCC AGGGATCTCC 
TACCAGAGAC TGGTGAGGGC TGAGCAGGGC CTGCCCATCA GGAGTCACCG CAGCTCCACC 
GTCACCGTGC TGCTGCTGAA CCCAGTGGAA GTGCAGGCCG AGTTCCTTGC TGTAGCCAAT 
AAGCTGAGTA CGCCCGGACA CTCGCCTCAC AGTGCCTACA CCACCCTGCT CCTGCACGCC 
TTCCAGGCCA CCTTTGGGGC CCACTGTGAC GTCCCGGGCC TGCACTGCAG GCTACAGGCC 
AAGACCCTGG CAGAGCTTGA GGACATCTTC ACGGAGACCG CAGAGGCACA GGAGCTGGCA 
TCTGGCATCG GGGATGCTGC AGAGGCCCGG CGGTGGCTCA GGACCAAGCT GCAGGCGGTG 
GGAGAAAAAG CTGGCTTCCC TGGGGTGTTA GACACTGCAA AACCAGGGAA GCTCCACACC 
ATCCCCATCC CTGTCGCCAG GTGCTACACC TACAGCTGGA GCCAGGACAG CTTTGACATC 
CTGCAGGAAA TCCTGCTCAA GGAACAGGAG CTACTCCAGC CAGGGATCCT GGGAGATGAT 
GAAGAGGAGG AAGAGGAGGA GGAGGAGGTG GAGGAGGACT TGGAAACTGA CGGGCACTGT 
GCCGAGAGAG ATTCCCTGCT CTCCACCAGC TCTTTGGCGT CCCATGACTC CACCTTGTCC 
CTTGCATCCT CCCAGGCCTC GGGGCCGGCC CTCTCGCGCC ATCTGCTGAC TTCCTTTGTC 
TCAGGCCTCT CTGATGGCAT GGACAGCGGC TACGTGGAGG ACAGCGAGGA GAGCTCCTCC 
GAGTGGCCTT GGAGGCGTGG CAGCCAGGAA CGCCGAGGCC ACCGCAGGCC TGGGCAGAAG 
TTCATCAGGA TCTATAAACT CTTCAAGAGC ACCAGCCAGC TGGTACTGCG GAGGGACTCT 
CGGAGCCTGG AGGGCAGCTC GGACACGGCC CTGCCCCTGA GGCGGGCAGG GAGCCTCTGC 
AGCCCCCTGG ACGAACCAGT ATCACCCCCT TCCCGGGCCC AGCGCTCCCG CTCCCTGCCC 
CAGCCCAAAC TCGGTACCCA GCTGCCCAGC TGGCTTCTGG CCCCTGCTTC ACGCCCCCAG 
CGCCGCCGCC CCTTCCTGAG TGGAGATGAG GATCCCAAGG CTTCCACGCT ACGTGTTGTG 
GTCTTTGGCT CCGATCGGAT TTCAGGGAAG GTGGCTCGGG CGTACAGCAA CCTTCGGCGG 
CTGGAGAACA ATCGCCCACT CCTCACACGG TTCTTCAAAC TTCAGTTCTT CTACGTGCCT 
GTGAAGCGAA GTCATGGGAC CAGCCCTGGT GCCTGTCCAC CCCCTCGGAG CCAGACGCCC 
TCACCCCCGA CAGACTCCCC TAGGCACGCC AGCCCTGGAG AGCTGGGCAC CACCCCATGG 
GAGGAGAGCA CCAATGACAT CTCCCACTAC CTCGGCATGC TGGACCCCTG GTATGAGCGC 
AATGTACTGG GCCTCATGCA CCTGCCCCCT GAAGTCCTGT GCCAGTCCCT GAAGGCTGAA 
GCCCAGGCCC TGGAGGGCTC CCCAACCCAG CTGCCCATCC TGGCTGACAT GCTACTCTAC 
TACTGCCGCT TTGCCGCCAG ACCGGTGCTG CTGCAAGTCT ATCAGACCGA GCTGACCTTC 
ATCACTGGGG AGAAGACGAC AGAGATCTTC ATCCACTCCT TGGAGCTGGG TCACTCCGCT 
GCCACACGTG CCATCAAGGC GTCAGGTCCT GGCAGCAAGC GGCTGGGCAT CGATGGCGAC 
CGGGAGGCTG TTCCTCTAAC ACTACAGATT ATTTACAGCA AGGGGGCCAT CAGTGGACGA 
AGTCGCTGGA GCAACCTGGA GAAGGTCTGT ACCTCCGTGA ACCTCAACAA GGCCTGCCGG 
AAGCAGGAGG AGCTGGATTC CAGCATGGAG GCCCTGACGC TAAACCTGAC AGAAGTGGTG 
AAAAGGCAGA ACTCCAAATC CAAGAAGGGC TTTAACCAGA TTAGCACATC GCAGATCAAA 
GTGGACAAGG TGCAGATCAT CGGCTCCAAC AGCTGCCCCT TTGCTGTGTG CCTGGACCAG 
GATGAGAGAA AGATCCTGCA GAGTGTAGTC AGATGTGAGG TCTCACCGTG CTACAAGCCA 
GAGAAGAGCG ACCTCTCCTC ACCACCCCAG ACGCCTCCTG ACCTGCCGGC CCAGGCCGCA 
CCTGATCTCT GCTCCCTTCT CTGCCTGCCC ATCATGACTT TCAGTGGAGC TCTGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256637.1
CDS	126..2765
Translation	MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVANKLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELASGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDILQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP

Target ORF information:

RefSeq Version	XM_005256580.3
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256580.3

ORF Insert Sequence:

ATGCAGCCAG GGGCCACGAC ATGCACGGAG GACCGCATCC AGCATGCCCT GGAACGCTGC 
CTGCATGGAC TCAGCCTCAG CCGCCGCTCC ACCTCCTGGT CAGCTGGGCT GTGTCTGAAC 
TGCTGGAGCC TGCAGGAGCT GGTCAGCAGG GACCCGGGCC ACTTCCTTAT CCTCCTTGAG 
CAGATCCTGC AGAAGACCCG AGAGGTCCAG GAGAAGGGCA CCTACGACCT GCTCACCCCG 
CTGGCCCTGC TCTTCTATTC CACTGTTCTT TGTACACCAC ACTTCCCACC AGACTCGGAT 
CTCCTTCTGA AGGCAGCCAG CACCTACCAC CGGTTCCTGA CCTGGCCTGT TCCTTACTGC 
AGCATCTGCC AGGAGCTGCT CACCTTCATT GATGCTGAAC TCAAGGCCCC AGGGATCTCC 
TACCAGAGAC TGGTGAGGGC TGAGCAGGGC CTGCCCATCA GGAGTCACCG CAGCTCCACC 
GTCACCGTGC TGCTGCTGAA CCCAGTGGAA GTGCAGGCCG AGTTCCTTGC TGTAGCCAAT 
AAGCTGAGTA CGCCCGGACA CTCGCCTCAC AGTGCCTACA CCACCCTGCT CCTGCACGCC 
TTCCAGGCCA CCTTTGGGGC CCACTGTGAC GTCCCGGGCC TGCACTGCAG GCTACAGGCC 
AAGACCCTGG CAGAGCTTGA GGACATCTTC ACGGAGACCG CAGAGGCACA GGAGCTGGCA 
TCTGGCATCG GGGATGCTGC AGAGGCCCGG CGGTGGCTCA GGACCAAGCT GCAGGCGGTG 
GGAGAAAAAG CTGGCTTCCC TGGGGTGTTA GACACTGCAA AACCAGGGAA GCTCCACACC 
ATCCCCATCC CTGTCGCCAG GTGCTACACC TACAGCTGGA GCCAGGACAG CTTTGACATC 
CTGCAGGAAA TCCTGCTCAA GGAACAGGAG CTACTCCAGC CAGGGATCCT GGGAGATGAT 
GAAGAGGAGG AAGAGGAGGA GGAGGAGGTG GAGGAGGACT TGGAAACTGA CGGGCACTGT 
GCCGAGAGAG ATTCCCTGCT CTCCACCAGC TCTTTGGCGT CCCATGACTC CACCTTGTCC 
CTTGCATCCT CCCAGGCCTC GGGGCCGGCC CTCTCGCGCC ATCTGCTGAC TTCCTTTGTC 
TCAGGCCTCT CTGATGGCAT GGACAGCGGC TACGTGGAGG ACAGCGAGGA GAGCTCCTCC 
GAGTGGCCTT GGAGGCGTGG CAGCCAGGAA CGCCGAGGCC ACCGCAGGCC TGGGCAGAAG 
TTCATCAGGA TCTATAAACT CTTCAAGAGC ACCAGCCAGC TGGTACTGCG GAGGGACTCT 
CGGAGCCTGG AGGGCAGCTC GGACACGGCC CTGCCCCTGA GGCGGGCAGG GAGCCTCTGC 
AGCCCCCTGG ACGAACCAGT ATCACCCCCT TCCCGGGCCC AGCGCTCCCG CTCCCTGCCC 
CAGCCCAAAC TCGGTACCCA GCTGCCCAGC TGGCTTCTGG CCCCTGCTTC ACGCCCCCAG 
CGCCGCCGCC CCTTCCTGAG TGGAGATGAG GATCCCAAGG CTTCCACGCT ACGTGTTGTG 
GTCTTTGGCT CCGATCGGAT TTCAGGGAAG GTGGCTCGGG CGTACAGCAA CCTTCGGCGG 
CTGGAGAACA ATCGCCCACT CCTCACACGG TTCTTCAAAC TTCAGTTCTT CTACGTGCCT 
GTGAAGCGAA GTCATGGGAC CAGCCCTGGT GCCTGTCCAC CCCCTCGGAG CCAGACGCCC 
TCACCCCCGA CAGACTCCCC TAGGCACGCC AGCCCTGGAG AGCTGGGCAC CACCCCATGG 
GAGGAGAGCA CCAATGACAT CTCCCACTAC CTCGGCATGC TGGACCCCTG GTATGAGCGC 
AATGTACTGG GCCTCATGCA CCTGCCCCCT GAAGTCCTGT GCCAGTCCCT GAAGGCTGAA 
GCCCAGGCCC TGGAGGGCTC CCCAACCCAG CTGCCCATCC TGGCTGACAT GCTACTCTAC 
TACTGCCGCT TTGCCGCCAG ACCGGTGCTG CTGCAAGTCT ATCAGACCGA GCTGACCTTC 
ATCACTGGGG AGAAGACGAC AGAGATCTTC ATCCACTCCT TGGAGCTGGG TCACTCCGCT 
GCCACACGTG CCATCAAGGC GTCAGGTCCT GGCAGCAAGC GGCTGGGCAT CGATGGCGAC 
CGGGAGGCTG TTCCTCTAAC ACTACAGATT ATTTACAGCA AGGGGGCCAT CAGTGGACGA 
AGTCGCTGGA GCAACCTGGA GAAGGTCTGT ACCTCCGTGA ACCTCAACAA GGCCTGCCGG 
AAGCAGGAGG AGCTGGATTC CAGCATGGAG GCCCTGACGC TAAACCTGAC AGAAGTGGTG 
AAAAGGCAGA ACTCCAAATC CAAGAAGGGC TTTAACCAGA TTAGCACATC GCAGATCAAA 
GTGGACAAGG TGCAGATCAT CGGCTCCAAC AGCTGCCCCT TTGCTGTGTG CCTGGACCAG 
GATGAGAGAA AGATCCTGCA GAGTGTAGTC AGATGTGAGG TCTCACCGTG CTACAAGCCA 
GAGAAGAGCG ACCTCTCCTC ACCACCCCAG ACGCCTCCTG ACCTGCCGGC CCAGGCCGCA 
CCTGATCTCT GCTCCCTTCT CTGCCTGCCC ATCATGACTT TCAGTGGAGC TCTGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Different inhibition of G??-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a G??-dependent regulator of PI3K? enzymatic activity.
The Biochemical journal469(1)59-69(2015 Jul)
Shymanets A,Prajwal,Vadas O,Czupalla C,LoPiccolo J,Brenowitz M,Ghigo A,Hirsch E,Krause E,Wetzker R,Williams RL,Harteneck C,N?rnberg B

Screening of differential promoter hypermethylated genes in primary oral squamous cell carcinoma.
Asian Pacific journal of cancer prevention : APJCP15(20)8957-61(2014)
Khor GH,Froemming GR,Zain RB,Abraham MT,Thong KL

p87 and p101 subunits are distinct regulators determining class IB phosphoinositide 3-kinase (PI3K) specificity.
The Journal of biological chemistry288(43)31059-68(2013 Oct)
Shymanets A,Prajwal,Bucher K,Beer-Hammer S,Harteneck C,N?rnberg B

A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia.
Human mutation33(2)351-4(2012 Feb)
Al Tassan N,Khalil D,Shinwari J,Al Sharif L,Bavi P,Abduljaleel Z,Abu Dhaim N,Magrashi A,Bobis S,Ahmed H,Alahmed S,Bohlega S

Phosphatidylinositol 3-kinase: the oncoprotein.
Current topics in microbiology and immunology34779-104(2010)
Vogt PK,Hart JR,Gymnopoulos M,Jiang H,Kang S,Bader AG,Zhao L,Denley A

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PIK3R5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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